libera/##covid-19/ Sunday, 2020-11-01

DocScrutinizer05>>how many<< I'm  sure you _could_ calculate that from inital_dose, time window observed, and concentration of virus in snot, given you know the exact amount of snot produced per minute;; or from initial dose applied, time window and ratio of damaged vs healthy cells times the total amount of cells available. 00:06
DocScrutinizer05afaik nobody bothered to do that calculation yet since it's worth nothing except for calculating the parameters you already needed to know to calculate the R value you asked for00:07
DocScrutinizer05ipw if you actually knew R, and you know initial dose and concentration of virus in snot after 24h, you could actually calculate the amount of snot per minute for that individuum00:11
DocScrutinizer05IOW*00:11
DocScrutinizer05>>thats interesting<< you completely lost me on that one00:12
ryoumawas just thinking that hcw are possibly already getting exposed to their patients and are well protected at work00:12
ryoumaor something like that00:13
ryoumaidk nm00:14
BrainstormNew from r/WorldNews: worldnews: WHO welcomes a contribution of US$ 90 million from The Kingdom of Saudi Arabia to support its COVID-19 global response. → https://is.gd/FyeU3A00:16
de-factoDocScrutinizer05, yes i guess that would be possible if such numbers would be available00:21
BrainstormNew from The Indian Express: World: Mob on street vs Covid deaths in hospital, US divide deepens in final countdown to Nov 3 → https://is.gd/v9lqwe00:34
CoronaBot04/r/coronavirus: UK Prime Minister Boris Johnson announces nationwide lockdown in England (10039 votes) | https://twitter.com/bnodesk/status/1322616352260169729?s=21 | https://redd.it/jlo59o00:50
rpifanyay00:52
de-facto%title https://www.bbc.com/news/uk-5476395601:04
Brainstormde-facto: From www.bbc.com: Covid-19: PM announces four-week England lockdown - BBC News01:04
DocScrutinizer05de-facto: my point being there's absolutely nothing *new* you could calculate now that you know the true "R" of virus in a particular individual's mucous membrane. All you can do is like a simple algebraic transformation of a formula with 3 known and no unknown variables01:06
de-factoyes indeed01:09
BrainstormNew from r/WorldNews: worldnews: Prime Minister Boris Johnson imposes stay-at-home order in England as coronavirus cases surge → https://is.gd/r7xNR701:11
de-factointeresting there also seems to be a cascade of lockdowns in EU now01:15
de-factosince this week01:15
metreoI wonder why?01:15
de-factoits good though, it hat to be hammered down aggressively01:15
de-facto*had01:16
de-factoidk maybe a threshold effect?01:16
LjLwait, there was actually a stay-at-home order? i displayed an impressive inability to follow and understand what Johnson said today. my understanding was that non-essential shops would close and some other stuff, but not that people would have to have a valid reason to leave their homes01:16
metreotip of the spear really01:17
metreoa lockdown by any other name01:17
LjLwell the term lockdown has been used to mean a number of different things by now01:17
metreoyes 01:18
LjLbut from the speech and what people said i had not realized there was a must-stay-at-home part01:18
metreothey're getting around to that I'm sure01:18
metreobetter not to slam on the brakes I think01:18
metreootherwise people will hoard plastic utensils01:19
LjLbut i mean that's what https://www.cnbc.com/2020/10/31/prime-minister-boris-johnson-imposes-stay-at-home-order-in-england-as-coronavirus-cases-surge.html claims01:19
LjL"People will be ordered to stay at home unless it’s for essential purposes, including education, medical reasons, or to shop for groceries, Johnson said during a press conference in London."01:19
LjLdid he?01:19
metreono I didn01:19
metreodidn't hear it like that*01:19
BrainstormNew from r/WorldNews: worldnews: 'Stay at home': UK PM Johnson imposes new national lockdown as Covid-19 cases top 1 million → https://is.gd/Hv4UPP01:20
LjLme neither, but i was distracted/confused01:20
metreohe did call it a lockdown01:20
metreoonce everybody is mostly settled in their homes they can start welding the doors shut01:21
LjLbut he also said it wasn't as tough as the one in Spring iirc01:21
LjL"the message is the same though"01:21
LjLpfft come on01:21
metreoit's that a lockdown like the spring is impossible01:21
metreothere will be escalating restrictions I mean01:21
metreoat least that's my prediction01:21
metreoBrits are freedom loving people 01:22
metreoyou can't order them all home in one go01:22
LjLthere are certainly being escalating restrictions here. but i am of the opposite opinion about slamming on the brakes. "chasing" the virus by enacting insufficient measures every time will only make it longer and worse01:22
LjLmetreo, you really like spouting back the bollocks you hear from politicians, don't you?01:22
LjL<metreo> Brits are freedom loving people01:22
metreoThere will be riots01:22
LjLour government expressed formal complaints about this very thing being stated by Johnson when he compared it to the Italian lockdown01:23
metreoReally? lol01:23
LjLas if Italians somehow didn't love freedom and it's a British (and obviously American) exclusive01:23
LjLyou know, most people who live in democracies "love freedom"01:23
LjL(and probably a few of those who don't)01:23
metreoIt's a nice way of saying there will be trouble in the streets01:23
metreoItalians are freedom loving people as well01:24
LjLwell, there is being trouble in the streets now in Italy, even though the restrictions have been escalating and not sudden01:24
LjLi actually think there would have been less protesting if there had been one sudden hard lockdown01:24
metreocatch everyone by surprise, hmm maybe yeah01:25
LjLas opposed to01:25
LjLevery single sunday01:25
LjLhear the PM's speech01:25
LjLadd more and more things you can't do01:25
LjLthat you can't even keep a list01:25
LjLevery single sunday a new law that will make people who can't do some things angry - and people who think it's not enough, also angry01:25
metreothey'll slap those angry people will shock value statistics01:26
metreolike today forecasting 1k dead/day01:26
metreonot a nice thought01:27
LjLa very realistic thought01:28
LjLit's what we had in spring01:28
LjLan optimistic thought maybe01:28
LjLto be fair - we didn't have it, we reached 919, on March 2701:29
LjLit's like a pretty large earthquake every day01:29
metreojesus01:30
LjLwithout people remaining homeless maybe, but still with a lot of people who are badly sick (and some who may stay sick for a very long time afterwards) aside from the ones who die01:30
LjLso putting "the economy first" would be a wee bit suicidal imo01:30
metreoit's a real conundrum01:33
LjLpostit: https://www.biorxiv.org/content/10.1101/2020.09.11.293951v2 hard evidence apparently found of virus presence in the CNS / brain01:34
metreoF01:35
LjLit's in one infant, who died (since an autopsy the easiest, or only, way to know for sure...)01:35
LjLmaybe it's not typical of other patients. maybe.01:36
metreothere has been work on that up until now01:36
metreoit has been suspected to cross the blood-brain barrier 01:36
DocScrutinizer05what still puzzles me is the synchronicity of run-away curves in virtually all countries01:37
BrainstormNew from BBC Health: Covid: What will the England lockdown achieve?: Lockdown is the measure nobody "wanted" but now many European countries have decided they "need". → https://is.gd/sfLIwR01:37
DocScrutinizer05as if weather in spain was same like in belgium or germany01:38
DocScrutinizer05I didn't look into this in any detail, it's just a gut feeling of sirts by now01:38
DocScrutinizer05sorts*01:39
metreolow temps high humidity 01:40
metreoprobably ideal for spread01:40
LjLmetreo, it has been suspected, yes, but an alternative explanation has often been that the virus didn't enter the CNS but instead other more indirect factors caused CNS inflammation. yuriwho, i think you thought it was the latter, maybe have a look at what you think of https://www.biorxiv.org/content/10.1101/2020.09.11.293951v2 ?01:40
ghost_rider[m]First person that I knew that passed away, was old > 80 ... everything I know it seems the lungs yada01:41
DocScrutinizer05~weather Algeciras01:41
DocScrutinizer05~weather hamburg01:41
LjLbot has no weather command, but if you're lucky you can get it from wolfram alpha...01:41
LjL%wa weather in Algerica, Hamburg01:41
LjLbut i am not lucky01:42
LjL%wa weather in Milan01:42
BrainstormLjL, failed to get any hits! 01:42
BrainstormLjL, failed to get any hits! 01:42
LjLDocScrutinizer05, if you want to spend time in spreadsheets, NOAA does have daily weather (temperature and humidity at least, you may want to look at windspeed too) data for all major airports01:42
LjLget it, correlate it with the infection curve, tada01:43
metreo.title https://www.sciencedirect.com/science/article/pii/S120197122030195801:45
Brainstormmetreo: From www.sciencedirect.com: A first case of meningitis/encephalitis associated with SARS-Coronavirus-2 - ScienceDirect01:45
DocScrutinizer05sounds like a plan, though I'm absolutely sure somebody alse must have done exactly that already, no?01:45
DocScrutinizer05else*01:46
DocScrutinizer05I always hear >>it's the weather<< but if officials had some charts supporting this claim they would already have shown them every full hour in the breaking news, no?01:48
metreolike a pollen forecast for covid spread01:48
metreoI don't think this is supported01:49
metreothere was speculation about low temps and high humidity after early out breaks in meat processing plants01:49
metreolooks like they're still struggling.. coincidence?01:50
metreo.title https://www.thestar.com/politics/2020/10/30/covid-19-a-second-olymel-meat-plant-in-quebec-dealing-with-outbreak.html01:50
Brainstormmetreo: From www.thestar.com: COVID-19: A second Olymel meat plant in Quebec dealing with outbreak | The Star01:50
DocScrutinizer05well, it should be damn easy to prove or falsify this, there is detailed meteorological data and history for each single city in the western world, just like per-city covid data01:58
DocScrutinizer05it's not even a master thesis level to calculate correlation01:59
metreoofc correlation is not causation02:00
metreomight as well correlate stock market to the weather as well02:01
DocScrutinizer05yes, they expected winter to get tough, but actually everybody was surprised to see the explosion *now* already, particularly since we don't exactly have an early autumn and winter this year02:01
de-factoDocScrutinizer05, that threshold effect puzzles me too, seems to go off in Scandinavian countries too now02:02
DocScrutinizer05not even a cold and wet summer02:02
de-factoit does not really seem to be weather related02:02
de-factoif i did not knew better i would think its almost like a pathogen with higher transmission ability arriving02:03
DocScrutinizer05exactly my thought, that's why 'I looked into  mutations and new strains, but nope02:05
de-factolook at Norway for example http://metrics.covid19-analysis.org/02:05
de-factonot so high incidence but same pattern like many other EU countries, first a little raise, kinda plateau and then at some point boOM02:06
de-factoits the same pattern in every country, very weird02:06
DocScrutinizer05weird02:06
metreoIreland is always cold and damp and they're doing fine02:06
de-factodo they have travel restrictions?02:07
metreonot sure tbh I haven't heard much from them02:07
de-factoireland also hat a peak though, but they seem to are beyond their peak02:07
de-factoneat02:07
metreopretty sure Mexico is not doing well and they are hot and dry02:07
de-factoits very weird, that threshold like effect, not really depending on weather or prevalence02:08
de-factogoing off in one EU country after the other02:08
metreomore of a seasonal influence like South Africa now entering summer02:09
metreoI don't understand how that works with viruses02:09
de-factobut there also were peaks in very hot weather, Arizona or Israel02:10
metreoit may defy logic02:10
metreoeven India is declining into Summer02:10
de-factoand the peak already started before it was getting cold in many places02:10
de-factosomehow i dont think its a purely seasonal effect02:10
metreoweird..02:10
de-factoit at all02:11
metreothe effect seems more real than the weather hypothesis02:11
metreowell India is actually equatorial02:11
metreowhat the heck is going on!!02:12
DocScrutinizer05when the moooon is in the seventh house, and jupiter aligns with mars... 02:12
metreo^exactly02:12
metreo:D02:12
de-factook correction: since testing is not really comparable we cant say if it is not a prevalence threshold 02:15
de-factoloool02:18
metreo:p02:18
DocScrutinizer05de-facto: has to be sth that immanently syncs vera large and distant reagions02:19
DocScrutinizer05very*02:19
de-factoyes02:19
metreoyeah it could be a population level biological change02:20
DocScrutinizer05unless it's a very precise timer in the DNA of virus itself, it's either some physical effect or information domain effect02:21
DocScrutinizer05RNA whatever02:21
metreoI meant changes in the host.., us02:21
DocScrutinizer05that would be the latter then02:21
metreoan information domain effect?02:22
DocScrutinizer05unless we *all* eaten same "catalytic" new fastfood last month02:22
BrainstormNew from r/WorldNews: worldnews: Obama praises Canada's COVID-19 response as he blames Trump for 'screw up' → https://is.gd/vgsq2802:23
LjL<DocScrutinizer05> sounds like a plan, though I'm absolutely sure somebody alse must have done exactly that already, no?  ←  it has been done, i can show you a study, but it was done long ago after the first wave. i don't know if they did it again after the second02:23
LjLwell, during the second02:23
DocScrutinizer05metreo: an effect triggered by spreading of information and causing us to change our behavior02:23
LjLDocScrutinizer05, here's the study https://www.medrxiv.org/content/10.1101/2020.03.18.20036731v1 plus i think this one is only about temperatures but i would look at humidity and wind too02:23
LjLunfortunately my understanding of probability and statistics is scarce02:24
DocScrutinizer05LjL: thanks a lot02:25
metreoooof Sean Connery passed02:26
metreo.title https://www.bbc.com/news/uk-scotland-5476210002:28
Brainstormmetreo: From www.bbc.com: First Minister leads tributes to 'global legend' Sean Connery - BBC News02:28
BrainstormNew from r/WorldNews: worldnews: Wuhan's streets are packed with Halloween revellers ten months after the coronavirus pandemic started there - while the rest of the world is crippled by pandemic → https://is.gd/1JejuH02:31
ghost_rider[m]Reddit and BBC, WoW02:35
de-factowell but on southern hemisphere there are many countries with R<102:52
de-factohmm maybe its really something seasonal after all02:52
de-factocombines with some sort of threshold effect, like exceeding of some resource and or prevalence "soaking through"02:53
de-facto*combined02:53
de-factolike South America, South Africa, Saudi Arabia, India, Indonesia, Phillipines, Australia02:54
de-factoall with R<102:55
rpifanhm02:58
de-factoI wonder about Ireland, they seem to have managed to reverse their incidence03:00
de-factotheir peak was around 18th Oct03:01
de-factoso it must be something around 4th Oct showing there03:01
de-factotwo weeks earlier03:01
metreowhat's the population density of Ireland?03:01
de-facto77.8/km^203:02
de-facto6-5M per 84421 km^203:02
de-facto6.5M per 84421 km^203:02
metreolondon is 5177 inhabitants per square kilometre03:02
metreoso about 67x more dense03:03
metreoItaly overall is 201 inhabitants per square kilometre03:03
de-facto"On 5 October, the Government rejected NPHET's recommendation to place the entire country under Level 5 restrictions, and instead moved every county in Ireland to Level 3 COVID-19 restrictions with improved enforcement and indoor dining in pubs and restaurants banned, which will come into effect from the midnight of 6 October until 27 October at the earliest."03:03
de-factocite from https://en.wikipedia.org/wiki/COVID-19_pandemic_in_the_Republic_of_Ireland03:04
metreo^that doesn't hurt :)03:04
metreoI live in a low population density area, and I've lived in big cities before03:04
metreoit makes a big difference in terms of the number of people you contact just stepping out03:04
metreolow population density with some restrictions seems like an ideal situation03:05
metreothat's what we have with 6 active cases out of 1M people03:06
de-factoso their level 3 lockdown is: gatherings: Maximum 6 from 1 other household, weddings max 25, no indoor events, outdoor events max 15 ppl, sports only alone indoors, outdoors max 15, restaurants, cafees, pubs Range of restrictions up to and including no indoor dining, hotels Services limited to residents only03:07
de-factoschoos open with protective measures03:07
de-factoso pretty much the "lockdown light" for Germany03:07
de-factothat may be good news03:08
de-factoDocScrutinizer05, look at ireland they reversed their peak after two weeks03:08
de-factohttp://offloop.net/covid19/?default=Germany;Ireland&byPopulation=yes&cumulative=no&smooth=yes03:09
de-factobut they moved into level 5 lockdown at 19th of Oct03:10
de-factothat cant have reversed the peak at 18th of Oct though, so it must have been the effect from that earlier measures03:11
de-factomaybe its really those party people's fault03:11
de-factoi think all events, restaurants, bars and clubs and party or other entertainment places should be closed permanently until vaccination03:22
BrainstormNew from r/WorldNews: worldnews: Australia records zero new locally acquired daily cases of coronavirus for first time since June → https://is.gd/PP8CL503:26
BrainstormNew from r/WorldNews: worldnews: Australia records first day without locally acquired COVID case since June → https://is.gd/uqXGtQ03:43
DocScrutinizer05hmmm >> This study provides preliminary evidence that there may be seasonal variability in transmission of SARS- CoV-2, but this analysis does not imply that temperature alone is a primary driver of COVID-19 transmission. The observed association may not be due directly to temperature, but to correlated factors such as relative humidity, or human behaviours during cold weather.<<03:45
DocScrutinizer05also this is for a really short observation window, so rather than watching at changes in incidences at a particular location driven by change of weather it simply seems to check for differences between warmer and colder countries / regions at one moment in time basically03:49
DocScrutinizer05very weak study03:50
de-factowhat is wrong with the cell.com servers? they never are able to deliver a full pdf to chrome03:52
de-facto%title https://www.sciencedaily.com/releases/2020/10/201029141938.htm03:55
Brainstormde-facto: From www.sciencedaily.com: More infections than reported: New study demonstrates importance of large-scale SARS-CoV-2 antibody screenings -- ScienceDaily03:55
de-facto"A new study indicates a six-fold higher SARS-CoV-2 exposure rate among children in Bavaria, Germany, than reported cases. This highlights the value of population-based antibody screenings for pandemic monitoring. The study also describes a novel approach to measuring antibodies against SARS-CoV-2 with high accuracy."03:55
de-facto%title http://dx.doi.org/10.1016/j.medj.2020.10.003 "Public health antibody screening indicates a six-fold higher SARS-CoV-2 exposure rate than reported cases in children"03:57
Brainstormde-facto: From dx.doi.org: Redirecting03:57
de-facto%title https://www.cell.com/med/pdf/S2666-6340(20)30020-9.pdf03:57
Brainstormde-facto, the URL could not be loaded 03:57
de-factowell it can be loaded with wget03:58
de-factoyou know cell.com servers are "special"03:58
BrainstormNew from Reddit (test): I voted today: Felt weird. I used my absentee ballot because I wasn't going to have time to stand in line for early voting, and I'm going to be out of town on voting day (bosses request (bs right?)) And it felt weird using my tongue to seal the envelopes.. seems not so sanitary, u know? → https://is.gd/Iwy68t04:02
DocScrutinizer05>>six-fold higher SARS-CoV-2 exposure rate among children<< I always wondered how reliable the research leading to the conclusion that schools may stay open. It seems to me they as well could be hidden drivers, maybe due to children being particularly non-susceptible to developing severe symptomatic ?04:16
DocScrutinizer05so maybe not temperature/season but schools?04:19
de-facto"Antibody surveillance in children during 2020 resulted in frequencies of 0.08% in January to March, 0.61% in April, 0.74% in May, 1.13% in June and 0.91% in July. Antibody prevalence from April 2020 was six-fold higher than the incidence of authority-reported cases (156 per 100,000 children), showed marked variation between the seven Bavarian regions (P<0.0001), and was not associated with age or sex. Transmission in children with 04:20
de-factovirus-positive family members was 35%; 47% of positive children were asymptomatic. No association with type 1 diabetes autoimmunity was observed. Antibody frequency in newborns was 0.47%."04:20
de-factohttps://covid-dashboard.fr1da-studie.de/app_direct/covid-dashboard/04:21
de-factoi am not sure, Ireland had schools open afaik?04:25
de-factoso i guess the takeaway message is that children are "stealth carriers" half of them asymptomatic and 5 of 6 cases go under the testing radar04:29
de-factonot quite sure how that compares to similar studies for adults though04:30
de-factopossibly may be similar in adults?04:30
DocScrutinizer05iirc the study Laschet was the first to base his pushing to open schools as they're supposedly no problem was by Streek04:59
DocScrutinizer05I'm not exactly convinced of the reliability and significance of Streek studies, nor of the interpretations Laschet does05:02
ryoumaif it is tru isn't that a bombshell?05:03
BrainstormNew from r/WorldNews: worldnews: Australia marks first day of no community COVID-19 transmissions in almost five months → https://is.gd/NeLhZg05:03
CoronaBot04/r/covid19: Treatment with Zinc is Associated with Reduced In-Hospital Mortality Among COVID-19 Patients: A Multi-Center Cohort Study (81 votes) | https://www.researchsquare.com/article/rs-94509/v1 | https://redd.it/jlspff05:03
DocScrutinizer05ryouma: for sure05:04
BrainstormNew from This Week In Virology: TWiV 677: Does antibody really know what time it is?: Daniel Griffin provides a clinical report on COVID-19, then we discuss rapid deployment of SARS-CoV-2 testing by research laboratories in San Francisco, longitudinal observation of antibodies to SARS-CoV-2 in patients, and listener questions on vaccines, loss of [... want %more?] → https://is.gd/CTTqKq05:12
BrainstormNew from The Indian Express: World: Trump failed to take pandemic, presidency seriously: Barack Obama → https://is.gd/YLjDMy05:21
ryoumai was wondering when former presidents would start talking05:26
yuriwhoyea, it's a travesty that that is necessary05:28
ryoumai want all of them to issue a joint statement05:28
BrainstormUpdates for Belgium: +16915 cases (now 429229), +173 deaths (now 11625) since a day ago — France: +13702 cases (now 1.4 million) since 7 hours ago — US: +4729 cases (now 9.4 million), +15 deaths (now 236072) since 7 hours ago — Netherlands: +763 cases (now 351941), +19 deaths (now 7414) since 15 hours ago06:05
BrainstormUpdates for Lombardy, Italy: +8919 cases (now 195744), +73 deaths (now 17535) since a day ago — France: +8840 cases (now 1.4 million), +19 deaths (now 36807) since 15 minutes ago — Netherlands: +2459 cases (now 354400), +13 deaths (now 7427) since 15 minutes ago — United Kingdom: +1567 cases (now 1.0 million), +45 deaths (now 46600) since 13 hours ago06:21
BrainstormNew preprint: Features of C-reactive protein in COVID-19 patients with different ages, clinical types and outcomes: a cohort study by Gaojing Qu et al, published on 2020-10-31 at https://medrxiv.org/cgi/content/short/2020.10.26.20220160 [... want %more?]07:21
BrainstormNew from The Indian Express: World: Australia sees zero local Covid cases for first time since June → https://is.gd/UR2E3507:36
BrainstormNew from The Indian Express: World: Protesters against COVID-19 restrictions clash with police in Spanish cities → https://is.gd/RNPNPM09:06
Haley[m]%cases usa10:10
BrainstormHaley[m]: In US, there have been 9.4 million confirmed cases (2.9% of the population) and 236077 deaths (2.5% of cases) as of 11 minutes ago. 144.8 million tests were performed (6.5% positive). Fatality can be broadly expected to lie between 1.1% (assuming prevalence as in tests) and less than 3.7% (considering only deaths and recoveries). See https://offloop.net/covid19/?default=US for time series data.10:10
Haley[m]%cases france10:11
BrainstormHaley[m]: In France, there have been 1.4 million confirmed cases (2.1% of the population) and 36807 deaths (2.6% of cases) as of 3 hours ago. 16.1 million tests were performed (8.7% positive). See https://offloop.net/covid19/?default=France for time series data.10:11
BrainstormNew from BBC Health: Covid-19: England gets ready for new four-week lockdown: The lockdown is due to run from Thursday to 2 December - but Michael Gove says it could be extended. → https://is.gd/iMy3ki10:18
Arsanerit%cases netherlands10:44
BrainstormArsanerit: In Netherlands, there have been 354400 confirmed cases (2.0% of the population) and 7427 deaths (2.1% of cases) as of 4 hours ago. 3.3 million tests were performed (10.6% positive). See https://offloop.net/covid19/?default=Netherlands for time series data.10:44
Arsanerit%cases germany10:44
BrainstormArsanerit: In Germany, there have been 531790 confirmed cases (0.6% of the population) and 10583 deaths (2.0% of cases) as of 4 hours ago. 21.9 million tests were performed (2.4% positive). Fatality can be broadly expected to lie between 0.5% (assuming prevalence as in tests) and less than 2.9% (considering only deaths and recoveries). See https://offloop.net/covid19/?default=Germany for time series data.10:44
BrainstormNew from ProPublica: Why Bush v. Gore Still Matters in 2020: by Ian MacDougall This article is part of Electionland , ProPublica’s collaborative reporting project covering problems that prevent eligible voters from casting their ballots during the 2020 elections. Sign up to receive our biggest stories as soon as they’re published. Twenty years [... want %more?] → https://is.gd/3sBNw011:20
BrainstormUpdates for US: +127 cases (now 9.4 million), +5 deaths (now 236077) since 5 hours ago11:22
BrainstormNew from Medical Xpress: Johnson announces month-long virus lockdown for England: Prime Minister Boris Johnson on Saturday announced a new four-week coronavirus lockdown across England, a dramatic shift in strategy following warnings hospitals would become overwhelmed within weeks under his current system of localised restrictions. → https://is.gd/HM4CdH11:29
BrainstormNew from Medical Xpress: England to lock down again as virus surges in Europe: Britain's Prime Minister Boris Johnson has announced a new four-week coronavirus lockdown in England, which will join several European countries in imposing the measure for a second time, as Slovakia took a different tack and began testing its entire population. → https://is.gd/fMhcc511:38
BrainstormUpdates for US: +2047 cases (now 9.4 million), +21 deaths (now 236098) since an hour ago — Switzerland: +4 deaths (now 2301) since 6 hours ago12:52
CoronaBot04/r/covid19: Influenza vaccination and hospitalizations among COVID-19 infected adults (83 votes) | https://www.jabfm.org/content/covid-19-ahead-print-subject-collection | https://redd.it/jlvnba13:36
BrainstormNew from r/WorldNews: worldnews: Israel begins human trials of domestically-produced Coronavirus vaccine → https://is.gd/JYeCmb13:42
BrainstormUpdates for Netherlands: +5461 cases (now 359861), +16 deaths (now 7434) since 8 hours ago — US: +59 cases (now 9.4 million), +3 deaths (now 236101) since 2 hours ago — Switzerland: +5 deaths (now 2306) since 2 hours ago14:53
BrainstormNew from r/Coronavirus: Coronavirus: Daily Discussion Post - November 01 | Questions, images, videos, comments, unconfirmed reports, theories, suggestions → https://is.gd/L6q4Kr14:54
aradeshis the offloop site down?15:19
BrainstormNew from Reddit (test): Covid2019: @GStephanopoulos : Counting the votes “might take some time in this election … and everyone watching at home should know that it is not a sign that anything has gone wrong.” Why voting in the coronavirus pandemic will be unlike any other year → https://is.gd/xcZWHj15:21
ghost_rider[m]Scientists discover ‘devastating’ NEW genetic disease that’s killed 40% of known patients by attacking lungs and immune system15:33
ghost_rider[m]At RT15:33
CoronaBot04/r/covid19: COVID-19 Artificial Intelligence Diagnosis using only Cough Recordings (83 votes) | https://www.embs.org/ojemb/articles/covid-19-artificial-intelligence-diagnosis-using-only-cough-recordings/ | https://redd.it/jlzerv15:55
aradeshseems back up again16:00
metreo.title https://j.mp/3mNDCsF16:30
Brainstormmetreo: From j.mp: Death rates among people with severe COVID-19 drop by a half in England. It’s possible that the higher death rates at the peak of the pandemic are in part because hospitals were so overcrowded at that [...]16:30
BrainstormNew from Reddit (test): CoronaVirus_2019_nCoV: U.S. Says Virus Can't be Controlled. China Aims to Prove It Wrong. → https://is.gd/t3HVdX16:33
BrainstormNew from Reddit (test): CoronaVirus_2019_nCoV: U.S. Hits Highest Single-Day Number of COVID-19 Cases for Any Country, England to Enter Lockdown → https://is.gd/qJFM4A16:41
BrainstormUpdates for Italy: +29905 cases (now 709335), +208 deaths (now 38826) since 23 hours ago — US: +11229 cases (now 9.4 million), +54 deaths (now 236155) since 2 hours ago17:24
JigsyHaircut day changed to Wed. \o/17:40
Jigsy%cases UK17:43
BrainstormJigsy: In United Kingdom, there have been 1.0 million confirmed cases (1.6% of the population) and 46717 deaths (4.5% of cases) as of 9 minutes ago. 33.5 million tests were performed (3.1% positive). See https://offloop.net/covid19/?default=United%20Kingdom for time series data.17:43
BrainstormNew from Reddit (test): Sunday 01 November Update: submitted by /u/HippolasCage to r/CoronavirusUK → https://is.gd/pbxE1A17:44
BrainstormNew from Reddit (test): China_Flu: Charlie Hebdo trial suspended as suspect catches Covid-19 → https://is.gd/Id3HTo18:02
ghost_rider[m]^^ lol, why not try new therapy.18:24
JigsyAre banks classified as non-essential?18:32
blkshpNo18:33
CoronaBot04/r/coronavirus: Slovakia tested 2 581 113 citizens in a single day with the antigen tests with positive rate about 1% (25 850); testing continues on Sunday across the nation (10036 votes) | https://www.aktuality.sk/clanok/836264/plosne-testovanie-takto-dopadol-prvy-den-v-cislach/ | https://redd.it/jlzmk118:44
JigsySure is warm outside...18:47
LjLde-facto, ↑ slovakia18:52
BrainstormNew from Reddit (test): China_Flu: Redditors en masse defend China's brutal lock-down strategy that involved welding families inside their homes and shooting anyone caught violating quarantine. → https://is.gd/cw2eGS18:56
tinwhiskersLol. That reddit title.19:07
LjLtinwhiskers, fwiw i just changed the sorting strategy for those subreddits to see if i can catch fewer cruft articles19:08
tinwhiskersAh. Cool.19:08
LjLit's currently https://old.reddit.com/user/LjLies/m/covid19ljl.rss?limit=519:10
LjLbut reddit rss is fiddly, there are many options but it's not immediately clear what sort of results they will... result in19:11
de-factoLjL, yeah Slovakia, they just do it, afaik with some light pressure, something like easing restrictions for participants in testing19:11
tinwhiskersI guess the anti lockdown people may be picking up their rhetoric with the need for lockdowns being so obvious now.19:11
LjLde-facto, it's antigen tests though so (didn't read the article) maybe they just do it themselves at home, making the only logistical hurdle obtaining the tests and mailing them19:12
de-factoi read something about testing centers19:12
LjLit's a lot of people to test in centers19:12
LjL%wa population of slovakia19:12
BrainstormLjL, Wolfram|Alpha (Slovakia | population): Result: 5.46 million people (world rank: 117th) (2019 estimate) → https://www.wolframalpha.com/input/?i=population+of+slovakia19:12
LjLde-facto, oh. the reddit thread makes me surmise they mostly haven't tested retired people, because basically the tests are required to go to work, so those without that incentive won't get tested :\19:14
LjLso forget about a good indication of real prevalence i guess19:14
LjLsample is very large but far from random19:14
LjL"However the only thing that absolutely confuses me is the fact that without a test they can't go to the doctors'."19:16
de-factoI wonder if it will be visible on their incidence, like ending a lot of infection chains at once19:18
LjLand someone says that many elderly people didn't go to get tested because the testing centers themselves may be a vehicle of contagion, while those elderly people may have not left their house in six months so they are unlikely to be positive19:18
LjLbut if it means you can't go to the doctor without a test, well, to me that seems like a bit of a shitty thing. i thought i remembered the EU recommending not to restrict people based on "immunity passports", nevermind passports that aren't even of immunity19:19
de-factomaybe the idea is not about immunity but rather about gathering sick people with the doctors and wanting to exclude SARS-CoV-2 contagion there?19:20
LjLwell, today we have just about as many cases in lombardy (and marginally fewer nationally) than yesterday despite less testing, like every sunday. which means a meaningfully higher percentage of positives.19:20
LjLde-facto, okay but again, what about gathering sick people together with non-sick people to take the test? and what about gathering almost-certainly-non-sick-but-vulnerable people (i.e. elderly who had been self-isolating all along) with sick people just so that they can go to their family doctor, which is particularly important for old people?19:21
LjLit seems like an ill-devised and not very humane thing to me, at least going by what these reddit comments say (the article doesn't like my ad blocker)19:22
de-factoyeah good points19:22
LjLanyway, pessimistic opinion piece of the day: https://www.thelancet.com/journals/lanmic/article/PIIS2666-5247(20)30151-8/fulltext19:22
de-factomaybe they should send the test (e.g. via postal service) to them in advance and have them do the test themselves19:23
LjLde-facto, might not work if the goal is keeping those sick from going to work, as people may lie if they do it themselves19:23
de-factoi still think the impact from such antigen tests only can really develop when they are used on LARGE scale and that means people have to do the tests themselves in my opinion19:23
LjLde-facto, well, aside from my ethical reservations on this, it was definitely done on a large scale, at least for the country involved... 50% or so of the population"19:24
LjLsomeone notes it's a very rural country and that makes it easier. i don't know if that's true, but i can imagine Milan would look like a mess if they decided to test EVERYONE in centers in a single day19:25
de-factoso if those detected positive normally would contribute to incidence (as in not knowing about their infectious status) i wonder how big the impact from telling them they have to isolate now is on incidence19:25
BrainstormNew from r/WorldNews: worldnews: Europe's COVID-19 cases double in five weeks, total infections surpass 10 million → https://is.gd/WaByda19:27
de-factoi guess we will see a peak from that massive testing, but hopefully after that incidence should reduce compared to a scenario without such large scale testing effort19:27
BrainstormNew from r/WorldNews: worldnews: Covid: New breath test could detect virus in seconds → https://is.gd/eGPD1U19:45
de-facto^^ interesting19:59
de-facto%title https://www.bbc.com/news/uk-wales-5471884819:59
Brainstormde-facto: From www.bbc.com: Covid: New breath test could detect virus in seconds - BBC News19:59
de-facto%title https://www.thelancet.com/journals/eclinm/article/PIIS2589-5370(20)30353-9/fulltext20:00
Brainstormde-facto: From www.thelancet.com: Diagnosis of COVID-19 by analysis of breath with gas chromatography-ion mobility spectrometry - a feasibility study - EClinicalMedicine20:00
metreodoes it detect bad breath as well :)20:03
BrainstormNew from Ars Technica: Gaming & Culture: NatGeo’s Virus Hunters showcases scientists racing to stop next pandemic → https://is.gd/08Fn5i20:03
LjLsee not all that gets posted from worldnews is crap20:03
LjL"In 80% of cases, they were able to accurately predict if the patient had Covid-19 - distinguishing the illness from other breathing problems such as asthma or bacterial pneumonia."20:04
LjLnot a great rate20:04
metreobut it reliable detected *an* illness20:05
metreodidn't read fwiw20:05
BrainstormNew from r/WorldNews: worldnews: Half of Slovakia's population tested for coronavirus in one day → https://is.gd/CexWyw20:57
BrainstormNew from r/WorldNews: worldnews: Mexicans celebrate restricted Day of the Dead amid coronavirus upheaval → https://is.gd/cEMadF21:33
BrainstormUpdates for Canada: +1565 cases (now 237477), +56 deaths (now 10192) since 15 hours ago — US: +40934 cases (now 9.5 million), +196 deaths (now 236351) since 4 hours ago — France: +23748 cases (now 1.4 million), +231 deaths (now 37019) since 15 hours ago — United Kingdom: +21687 cases (now 1.0 million), +162 deaths (now 46717) since 15 hours ago22:05
BrainstormNew from Medical Xpress: New English lockdown could last longer than month, govt says: A new four-week coronavirus lockdown in England will be extended if it fails to reduce infection rates, the government said Sunday, as it faced criticism over the abrupt decision to shut down again. → https://is.gd/DPO41622:09
CoronaBot04/r/covid19: SARS-CoV-2 viral load is associated with increased disease severity and mortality (88 votes) | https://www.nature.com/articles/s41467-020-19057-5 | https://redd.it/jm7h4y22:15
BrainstormNew from Medical Xpress: Israel begins coronavirus vaccine trials: Israel began clinical trials of a novel coronavirus vaccine on Sunday, authorities said, as the government loosens a second lockdown imposed to stem soaring infections. → https://is.gd/i5leCX22:27
CoronaBot04/r/covid19: Slight reduction in SARS-CoV-2 exposure viral load due to masking results in a significant reduction in transmission with widespread implementation (82 votes) | https://www.medrxiv.org/content/10.1101/2020.09.13.20193508v2 | https://redd.it/jm8omo22:39
prodormo[m]Are mathematical models trustworthy? The imperial college study was awfully inaccurate, and to make a model about masks and coronavirus we need to make assumptions about mask efficacy at blocking viral prticles. If somebody knows of such studies could they please cite them, i fail to find them in the Goyal study.23:03
BrainstormNew from r/WorldNews: worldnews: Coronavirus: Spain's funeral homes strike as cases rise → https://is.gd/SHoZNE23:03
tinwhiskersprodormo[m]: it's a very broad question. Mathematical models are pretty much never absolutely correct. The less-well you have parametrised the model, the less accurate it will be, therefore the less you understand what you are modelling the worse the outcome. We knew very little, and still know very little about many aspects of covid. Added to that, if you're modelling anything that involves human behaviour it's always going to be 23:19
tinwhiskerstricky.23:19
tinwhiskersHowever, they are still the best way to have to make predictions.23:19
tinwhiskersIn particular they are useful for sensitivity analysis; that is to see which parameters in your model results in the largest changes in model result, showing what things need more study to pin down better data, and those things that we most need to concentrate management efforts on.23:21
tinwhiskersSo you may well be able to say, if we do X then the results are likely to be better than if we do Y, however if you want precise values then most models will leave you disappointed. They are good for comparing scenarios though.23:22
prodormo[m]Cool, i just now found the mingming (2020) metaanalisis, in which i suppose they are basing their model on. Up to now i only knew about the 2009 metaanalisis by Xiao, so i guess i had obsolete info, thanks for the reply.23:28
tinwhiskersprodormo[m]: as for mask efficacy in the models, that's a small and relatively straight-forward component of the spread. How humans actually behave is going to a be a source of much more variation. Considering the political nature of mask and distancing behaviour you're making some pretty wild guesses.23:28
tinwhiskerss/variation/uncertainty/23:30
BrainstormNew from r/WorldNews: worldnews: Brazilians protest mandatory COVID-19 immunization, Chinese vaccine → https://is.gd/QyxamX23:47
JigsyThe lockdown could (read as will) be expended past December 2nd.23:55
Jigsyextended*23:55
tinwhiskersYeah, seems almost certain it will need to be.23:57

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