libera/##covid-19/ Wednesday, 2021-02-03

DocScrutinizer05LjL: tobypus joined for logging17:54
BrainstormUpdates for United Kingdom: +26739 cases (now 3.9 million), +2218 deaths (now 109335) since 23 hours ago17:56
ArsaneritDocScrutinizer05: isn't "desperately" and "hope" somewhat in contradiction?18:12
ArsaneritAre they by now monitoring the prevalence of the variants systematically with large enough sample sizes?18:13
DocScrutinizer05yes, and the results are about to emerge / get published any day now by $official-entity (no idea if it was RKI, PEI, whomever does the aggregation). Drosten yesterday spoilered >>some one digit percentage<< and Lauterbach at Lanz said >>10 to 15%<<18:21
DocScrutinizer05Drosten warned about taking the first emerging numbers with a grain of salt as they will adjust some more towards the final value18:23
DocScrutinizer05wow, 303 users18:24
DocScrutinizer05RaDVaC – Rapid Deployment Vaccine Collaborative (opensource) https://radvac.org/18:47
DocScrutinizer05^^^ interesting18:47
DocScrutinizer05.tell LjL RaDVaC – Rapid Deployment Vaccine Collaborative https://radvac.org/18:52
BrainstormDocScrutinizer05, I'll pass LjL your message when they are around.18:52
DocScrutinizer05nasal application18:53
DocScrutinizer05CC BY 4.018:53
CoronaBot/r/covid19: Oxford AstraZeneca Data, Again (82 votes) | https://blogs.sciencemag.org/pipeline/archives/2021/02/03/oxford-astrazeneca-data-again | https://redd.it/lbrb9m18:55
BrainstormUpdates for Italy: +13182 cases (now 2.6 million), +476 deaths (now 89820) since 23 hours ago — Switzerland: +43 deaths (now 9530) since 21 hours ago19:04
BrainstormUpdates for Spain: +30194 cases (now 2.9 million) since 23 hours ago — British Virgin Islands: +17 cases (now 114) since 28 days ago — Netherlands: +52 deaths (now 14169) since 20 hours ago19:54
BrainstormNew from Medical Xpress: Spain virus death toll surges past 60,000: govt: Spain's coronavirus death toll surged passed the 60,000 mark on Wednesday as another 565 people died in the previous 24 hours, health ministry figures showed. → https://is.gd/wubwUA19:59
CoronaBot/r/coronavirus: The AstraZeneca vaccine is shown to drastically cut transmission of the virus. (10160 votes) | https://www.nytimes.com/2021/02/02/us/astrazeneca-coronavirus-vaccine.html | https://redd.it/lbjzik20:01
BrainstormNew from Medical Xpress: Most vulnerable often overlooked in clinical trials of new treatments for COVID-19: Studies examining the effectiveness of treatments for COVID-19 often do not include the very populations hardest hit by the disease, according to a new review by University of Chicago Medicine researchers. → https://is.gd/atLLww20:46
LjLDocScrutinizer05, uhm... i don't really like some of the things it claims on that RadVac page tbh. for instance "The result is that commercial vaccines that were designed and produced in a few weeks are taking at least a year to reach most people" is directly contrary to what Derek Lower published yesterday here https://blogs.sciencemag.org/pipeline/archives/2021/02/02/myths-of-vaccine-manufacturing where he complains: I’ve seen a number of people sa20:51
LjLy something like “We had the vaccine back in February! It only took until the end of the year to roll it out because of the FDA!”20:51
LjLand encouraging people to just test vaccines on themselves rather than having clinical trial, just because "it's faster" O.o no please20:52
de-facto.title https://www.youtube.com/watch?v=ccxt-ByJ53Q20:57
Brainstormde-facto: From www.youtube.com: COVID cases in Portugal rise rapidly, Germany sends support - YouTube20:57
de-factoportugal is one of the countries with *lowest* capacity in ICU beds per capita https://en.wikipedia.org/wiki/List_of_countries_by_hospital_beds20:59
de-factothere are reports that people wait for a *day* in the emergency transports because there are queues and triage at the hospital entries20:59
gigasu_shidai'm worried that many nurses will quit and go do something else21:00
de-factohttps://coronavirus-portugal-esriportugal.hub.arcgis.com/ https://www.arcgis.com/apps/opsdashboard/index.html#/acf023da9a0b4f9dbb2332c13f63582921:01
de-factohttps://virological.org/t/tracking-sars-cov-2-voc-202012-01-lineage-b-1-1-7-dissemination-in-portugal-insights-from-nationwide-rt-pcr-spike-gene-drop-out-data/60021:03
de-factohopefully that is not like a preview into what we might see in the other EU countries incubating B.1.1.7 aswell21:11
LjLde-facto, it also pointed out somewhere that Portugal's physical position at the edge of Europe just doesn't help with transferring patients elsewhere21:11
de-factoindeed21:13
IndoAnonLjL: sorry, need to switch chan21:15
IndoAnonWe're vaccinating mostly the public servant(including nurses and doctors)21:17
LjLsame here... at least until recently, since now we're kinda out of vaccines21:18
IndoAnonDamn21:18
LjLwell no, we're vaccinating *mainly* nurses and doctors, not public servants in general21:18
IndoAnonAnd still running out? that must be the reason why EU accept the israeli-russian stuff21:19
LjLyeah with all of Pfizer, Moderna and AstraZeneca (although only Pfizer is actually in use so far, but we must account for second doses) announcing cuts compared to their initial production forecast...21:19
LjLIndoAnon, yeah, we're really not receiving nearly enough vaccines. the russian vaccine came out with a phase 3 study that looks good. don't know what else to say about it.21:20
IndoAnondammit, they never learn, do they?21:20
LjLvaccines are not that easy to produce, apparently!21:20
IndoAnonwell21:20
LjLhttps://blogs.sciencemag.org/pipeline/archives/2021/02/02/myths-of-vaccine-manufacturing21:20
BrainstormUpdates for France: +23342 cases (now 3.3 million), +480 deaths (now 77283) since 22 hours ago21:21
LjLnot justifying it but when people (including sometimes me) say "damn they should just enlist every company to produce it", well it's not that easy21:21
LjLSanofi has offered to help produce Pfizer (since their own vaccine is being delayed), but they also say they won't be ready until August21:21
IndoAnonThere's enough time to retrofit other facilities across the globe.21:21
LjLit's being done, but "enough time" is measured in months21:21
IndoAnonBut, they didn't do it. Man21:21
IndoAnonYeah, from march last year to december...21:22
LjLyeah then thing is, these companies (especially Moderna) only announced that they wouldn't provide as much as promised abruptly21:22
LjLso we didn't *know* we'd have this shortage until quite recently21:22
IndoAnonsupposedly site "upgrade"21:23
LjLit's not just that21:23
LjLthere's also been the excuse that we can now officially use 6 doses instead of 5 out of each vial21:23
LjLand they're taking that to mean their obligations are fulfilled with that 6th dose21:23
LjLeven though it has to be extracted in ways that don't really always mean you can get it21:24
LjLanyway, time for me to treadmill a bit or i'll become glued to the chair21:24
de-factobtw i heard that there is a German company called BioNTech that developed an mRNA vaccine called BNT162b2 and collaborate with American company Pfizer, they expect to increase the production by 50% in 2021 (compared to their estimates before)21:28
de-facto.title https://investors.biontech.de/news-releases/news-release-details/statement-manufacturing21:28
Brainstormde-facto: From investors.biontech.de: Statement on Manufacturing | BioNTech21:28
DocScrutinizer05LjL: it's a vompletely open source project, I don't care what they encourage or claim, except for the mere medical/scientific rationale21:32
DocScrutinizer05it's a) a mere peptide which I for myself would consider safe enough to snort it  b) nasal application which basically wouldn't even need an approval  c) seems within reach to produce myself  d) an interesting (I can'T tell yet if any reasonable promising) approach regarding its operation principles21:37
BrainstormUpdates for Canada: +3581 cases (now 790052) since 23 hours ago22:04
BrainstormNew from Ars Technica: Science: GSK eyes next-gen COVID vaccine as it inks deal to help boost current supply → https://is.gd/vmhvAz22:16
pigzuujust got Pfizer shot #2 ..22:30
DocScrutinizer05ooh I forgot: I heard there are first results reagrding transmission protection from vaccination, aka "sterile immunity". Definitely no sterile immunity in >95%. Probably very good immunity in >70%22:30
DocScrutinizer05the whole "privileges for the vaccinated" is a moot fight22:31
pigzuuDocScrutinizer05, your saying neg testing may still be required for those post vax22:32
de-factoyes of course, how would you know in advance with 100% certainty how to react when exposed to a new variant of the pathogen? Probability is very much would support to assume "just fine" but not with 100% certainty23:05
de-factopigzuu, congratz btw i have to admit i envy you a bit for that :P23:07
de-factoprotection from symptomatic disease is very very good, probably beyond all expectations prior to the first trial stats being published23:09
de-factopigzuu, out of curiosity, how are the side effects on 1st shot compared to 2nd shot for the BioNTech/Pfizer BNT162b2 shots?23:10
pigzuude-facto, for me just the injection soreness, with shingles 2nd dose I had a week of the flu complex type symptoms23:13
pigzuuwe'll see on the 2nd BNT, just got it so23:13
de-factoits always interesting to hear first hand experience for it23:21
BrainstormNew from Ars Technica: Science: Russia’s Sputnik V vaccine looks good in early analysis → https://is.gd/XTI9Yc23:22
de-factowould be very nice if you can keep us updated23:23
pigzuuwill do23:23
de-factothanks23:23
BrainstormNew from Virological.org: Latest posts: Phylogenetic relationship of SARS-CoV-2 sequences from Amazonas with emerging Brazilian variants harboring mutations E484K and N501Y in the Spike protein: Update of the SARS-CoV-2 genomic surveillance in the Amazonas state, Brazil Here follows an update of our previous post showing lineage assignment of 114 [... want %more?] → https://is.gd/1XpJeh23:59

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