libera/##covid-19/ Sunday, 2021-03-28

CoronaBot/r/coronavirus: "No evidence" to support former CDC director's theory that coronavirus escaped from lab, scientists say (10001 votes) | https://www.cbsnews.com/news/coronavirus-origins-lab-theory-robert-redfield-controversy/ | https://redd.it/mebavc01:29
LjLde-facto, https:/old.reddit.com/r/Coronavirus/comments/mebavc/no_evidence_to_support_former_cdc_directors/gshe7c3/01:35
LjL"With the implementation of enhanced community quarantine in the Greater Manila area starting Monday, Presidential spokesman Harry Roque said authorities will be do a house-to-house search for possible COVID-19 patients. In a briefing on Saturday, Roque assured the public this will not violate human rights since this is part and parcel of the quarantine."01:47
LjLlol, that sure sounds like a convincing explanation of why it's not a violation01:47
BrainstormNew from r/WorldNews: worldnews: Brazil’s COVID-19 Crisis Spirals Out Of Control: ‘An Open-Sky Laboratory For Viral Mutations’ - More than 300,000 Brazilians have died from the coronavirus, and far-right President Jair Bolsonaro’s denial of the crisis is putting the whole world at risk. → https://is.gd/hVIsG403:57
LjL:\03:58
derpadmin:(04:05
derpadminpeople in power like Bolsonaro and trump that spread falsehood should be held accountable04:06
derpadminlike hard jail time04:06
derpadminwe are talking hundred thousands of human lives here04:06
derpadmin(be hold)04:06
BrainstormNew from Reddit (test): China_Flu: Bill 6721 "COVID–19 Hate Crimes Act" (Section 2.C(2) could be problematic for the title of this subred) → https://is.gd/TynFHv05:40
BrainstormNew from The Indian Express: World: 5,000 attend rock concert in Barcelona after COVID-19 screen → https://is.gd/AjvEoN06:01
BrainstormNew from This Week In Virology: TWiV 736: Rhapsody in T with Alessandro Sette: Alessandro Sette joins TWiV to discuss the role of T cells in COVID-19, the finding that amino acid changes in SARS-CoV-2 variants of concern have a negligible impact on T cell reactivity in convalescent patients and vaccinees, and whether a next generation vaccine should [... want %more?] → https://is.gd/PMcGyF06:12
BrainstormNew from The Indian Express: World: Hong Kong says initial investigation of BioNTech vaccines shows no ‘obvious systemic factors’ → https://is.gd/p28Qlf06:43
BrainstormNew from The Indian Express: World: A collapse foretold: How Brazil’s Covid-19 outbreak overwhelmed hospitals → https://is.gd/8obGLt07:14
gigasu_shidahttps://www.dw.com/en/coronavirus-barcelona-holds-music-concert-with-5000-to-test-hygiene-measures/a-5702878607:18
gigasu_shidawhat the heck....why is Spain doing this07:18
BrainstormNew from The Indian Express: World: Suicide and Self-Harm: Bereaved Families Count the Costs of Lockdowns → https://is.gd/aHXVnk07:35
BrainstormNew from r/WorldNews: worldnews: Foreigners flock to Serbia to get free coronavirus vaccine → https://is.gd/IKfb2l07:55
darsieAstraZeneca08:20
BrainstormNew from r/Coronavirus: Daily Discussion Thread | March 28, 2021: Please refer to our Wiki for more information on COVID-19 and our sub. You can find answers to frequently asked questions in our FAQ , where there is valuable information such as our: → https://is.gd/nX3s5i09:08
BrainstormNew from BBC Health: Covid: Boris Johnson urged to share vaccines with poorer nations: A group of charities is calling on Boris Johnson to begin donating vaccines through the Covax scheme. → https://is.gd/vixD8s10:31
BrainstormNew from The Indian Express: World: UK variant hunters lead global race to stay ahead of COVID → https://is.gd/dqJHNC11:33
BrainstormNew from r/WorldNews: worldnews: Mexicans Travel To U.S. For COVID Vaccines As Mexico's Rollout Stumbles : NPR → https://is.gd/j7Egve11:43
BrainstormNew from Ars Technica: Science: The ionizer in your kid’s school may not do much to fight COVID → https://is.gd/ap8JWL13:16
BrainstormNew from BBC Health: (news): Covid: Another lockdown 'last thing in world' that government wants → https://is.gd/LRclwG14:39
de-factothis morning got a push notification via NINA app, stating the new regulations Merkel and her ministers agreed upon will become effective, there is the threshold of weekly 100 infections/100k citizens, but it will not change contact restrictions (e.g. people meeting in private places etc). Guess how they call this...14:45
de-facto...drumroll...14:46
de-facto..."emergency brake".14:46
de-factoEffectively before the last corona conference we had more strict rules than after it, but instead of calling it "lifting restrictions and opening" (summarizing their failure to appropriately react to exploding new infections) they rather call it "emergency break" in the hope they can hide behind that term despite all that is left from the properties of a break is nothing but the empty word itself.14:48
BrainstormNew from Ars Technica: Gaming & Culture: 20-sided smart dice over the rainbow: Ars tests $39 LED-filled Pixels Dice → https://is.gd/Jd4hAS14:50
de-factothat is how government gains trust in their, uhm, "leadership".14:52
de-facto.tell LjL https://nitter.cc/kakape/status/137581954301736550515:11
Brainstormde-facto, I'll pass LjL your message when they are around.15:11
BrainstormNew from Derek Lowe: @Dereklowe: I’m not happy about this, either. But my hope is that we’re seeing the damped-down version of what would have been a much larger wave.It’s a vaccination race, and folks need to hold things together a bit longer. . . → https://is.gd/oHtitn15:33
BrainstormNew from The Indian Express: World: Coronavirus digest: Mexico reports 120,000 ‘untested’ deaths → https://is.gd/d8VXZL16:47
CoronaBot/r/covid19: Monozygotic twins discordant for severe clinical recurrence of COVID-19 show drastically distinct T cell responses to SARS-Cov-2 (82 votes) | https://www.medrxiv.org/content/10.1101/2021.03.26.21253645v1 | https://redd.it/mexbby17:02
-RSSBot[LjLmatrix- Feed: "A sostegno di chi ha più bisogno", Draghi partecipa all'iniziativa di solidarietà alimentare ( http://www.governo.it/it/articolo/sostegno-di-chi-ha-pi-bisogno-draghi-partecipa-alliniziativa-di-solidariet-alimentare/16508 )17:17
BrainstormNew from Reddit (test): Sunday 28 March 2021 Update: submitted by /u/HippolasCage to r/CoronavirusUK → https://is.gd/tpPxUN17:18
BrainstormNew from r/WorldNews: worldnews: UK variant hunters lead global race to stay ahead of COVID → https://is.gd/v2omb317:50
BrainstormNew from r/WorldNews: worldnews: Foreigners flock to Serbia to get coronavirus vaccine shots → https://is.gd/QQcoGn18:11
BrainstormNew from r/WorldNews: worldnews: US breaks record for most COVID-19 vaccines administered in a day → https://is.gd/e1SvO218:32
BrainstormNew from r/WorldNews: worldnews: Trudeua promises ''Canada to receive 6.5 million Covid-19 vaccines by end of March''...where are they? → https://is.gd/6DZ5ie18:42
BrainstormNew from r/WorldNews: worldnews: Mexico says COVID-19 deaths likely 60% higher than confirmed toll → https://is.gd/yhWFwd19:03
BrainstormNew from r/WorldNews: worldnews: Former Clinton administration NSC official says China didn't allow international experts to do primary research into coronavirus origin → https://is.gd/OwVwwk19:23
BrainstormNew from NPR: U.S. Is In A Race Between Vaccines And Variants, Says Public Health Expert: Despite the progress in vaccinating Americans, there's concern about the threat posed by COVID-19 variants. The White House is urging not to "let down our guard." → https://is.gd/r7cg5b19:34
LjLde-facto, "The mechanism is still unclear but the researchers we talked to all agreed that the symptoms were so particular that it looked like something real caused by the vaccine."20:26
LjLthe researchers, but evidently not the WHO or EMA20:27
LjLand then you wonder why i distrust those agencies20:27
LjLand a comment from some "pro-vax" person that i now pretty much equate to "anti-vax" in terms of enormities they say:20:30
LjL"This is the height of irresponsible journalism. Vaccine skeptics will most likely not get past the the title of the article. What should be highlighted are the risk of acquiring Covid, risk of hospitalisation, risk of death and risk of vaccine. <1in a millions far less than rest!"20:30
LjLso we shouldn't be able to read that information because "vaccine skeptics" will use it20:30
LjLoh noes, oh my god, information is dangerous20:31
BrainstormNew from Politico: Coronavirus: Slovak Prime Minister Igor Matovič steps down over vaccine crisis → https://is.gd/SPjcon20:36
LjL"Norway, which has administered the AstraZeneca vaccine to 130,000 people under 65, has reported five patients who had low platelets, hemorrhage, and widespread thromboses, three of whom died. That's about one case in 25,000 vaccinees, "a high number with a very critical outcome in previously healthy, young individuals,” says Watle."20:38
LjLif someone wants to ignore this, they are actively trying to endanger people.20:38
rpifanhow so?20:42
LjLby insisting they do something whose risks outweight the benefits.20:43
LjLit works both ways20:43
BrainstormNew from r/WorldNews: worldnews: Netherlands: Churchgoers breaking COVID rules attack journalists. Worshipers flouting pandemic measures in the Netherlands have responded to media attention with violence. Lawmakers have slammed the attacks on reporters → https://is.gd/iGFza720:46
rpifanwell one case in 25,000 really isnt that bad20:46
LjLif it's more than COVID causes, it's obviously bad20:47
rpifani thought looking at it globally covid was worse20:55
LjLyes, well, looking at it in Norway, the vaccine seems worse20:56
LjLdifferent situations may apply to different places20:56
LjLjust making a worldwide average and going from that doesn't seem ideal20:56
LjLde-facto, do you remember we saw some PDF or something with UK vaccinations divided by type of vaccine...?20:57
BrainstormNew from r/WorldNews: worldnews: Heroes to zeros: how German perfectionism wrecked its Covid vaccine drive → https://is.gd/xD1kzL20:57
LjLde-facto, https://www.gov.uk/government/publications/covid-19-variants-genomically-confirmed-case-numbers/variants-distribution-of-cases-data  UK-specific, but pretty specific21:10
BrainstormNew from r/WorldNews: worldnews: US gives $15m to Palestinians to fight against COVID-19 → https://is.gd/lP07Na21:17
de-factointeresting, wonder if they got time series for that21:54
BrainstormNew from r/WorldNews: worldnews: In country known for whale hunts, Covid has been good for the creatures → https://is.gd/SNciES22:09
de-facto.title https://www.sciencemag.org/news/2021/03/rare-clotting-disorder-may-cloud-worlds-hopes-astrazenecas-covid-19-vaccine22:10
Brainstormde-facto: From www.sciencemag.org: A rare clotting disorder may cloud the world's hopes for AstraZeneca's COVID-19 vaccine | Science | AAAS22:10
de-facto"...Greinacher, who calls the syndrome vaccine-induced prothrombotic immune thrombocytopenia, or VIPIT. Greinacher says he has submitted a manuscript to the preprint server Research Square." i cant find that paper, is there something like an internal preprint review or such?22:11
de-factoin particular i am curious about if they mention a cofactor22:23
pwr22I really hope this astrazeneca thing doesn't turn it to be too bad or target that all the vaccines cause it but just got noticed more in astrazeneca first22:24
pwr22If it's a kind of auto immune thing caused by the antibodies generated, couldn't that in theory be triggered by any immune response?22:24
de-factoit even could be asked: has it been investigated if such mechanisms also possibly could happen with severe/fatal COVID?22:25
de-factoit could have been "shadowed" by the patients being given Heparin hence the MDs assuming the Heparin as cause if they would find something like that in severe/fatal COVID22:26
de-factoafter all its assumed to be very rare22:26
de-factoi.e. how can it be excluded that the s-protein itself does something to the immune system that may cause such progressions when a severe inflammation reaction is going on?22:28
LjLde-facto: I would tend to exclude it due to the lack of similar reports about BNT and Moderna22:29
BrainstormNew from Reddit (test): China_Flu: "The odds that this virus is natural are very low" Wuhan Institute of Virology highly probably source → https://is.gd/hrCaih22:30
de-factohence: does it happen only in ChAdOx1 or also Ad5/Ad26 vectors? how about the mRNA vaccines? and how about severe COVID cases (treated with heparin and treated without heparin)?22:30
rpifando yall really believe the lab theory22:31
de-factoanother difference: the s-protein in AZD1222 does not have the two point mutations in the s-protein to stabilize it in its prefusion config22:31
de-factorpifan, no but i do believe the first sequence was not so close to the event where the virus first has seen human cells (because one would expect it to adjust with mutations to its new host)22:33
de-factoso maybe it evolved in human population "under the radar" and only when it became optimized enough that it really took off it was discovered and sequenced?22:34
rpifanidk what to believe22:34
rpifanim also in favor of the being natural22:34
de-factoat least that would be supported by the earlier sequences (e.g. in Italy etc)22:34
rpifanbut at this point the news is really pushing hard22:34
de-factounfortunately we dont have a s-protein sequence from those afaik22:35
de-factobecause those early sequences are incomplete (at least when i investigated them the last time)22:35
de-factowhat i am trying to say is that there is no clear evidence for lab origin, but also nothing that could exclude that22:37
LjLI think there was some impressive "pushing hard" towards the natural theory earlier... When the lab theory gets brought up there's screams of "no evidence!" but what's the strikingly decisive evidence for the natural theory?22:44
rpifanidk22:45
rpifanis there any22:45
rpifanhow do you prove its natural22:45
LjLthere is a paper from a good while ago that purports to prove it's natural22:46
LjLi'm far from convinced, but i guess they thought they had decent ways to show it22:46
LjLi guess the closest you get to "proving it's natural" is showing that it's perfectly plausible for all of its characteristics to have arisen naturally in a compatible timeframe22:47
LjLyou can't rule out it went "through" a lab, unless you find the exact "patient zero" and all of their chain, which at this point is pretty much impossible i guess22:48
de-factowell assuming the absence of certain characteristics (e.g. cut and paste RNA frames) can only rule out the most naive approaches i would assume (but probably not some like smart breeding), but how can we assume that this would cover *any* possible other origin than a zoonotic event?22:56
de-factomy assumption: there wont be a proof of either way ever22:57
de-factoit seens that SARS-CoV-2 can jump across species barrier pretty easily, as we noticed also back from humans into animals (and then do some slight convergent mutations such as Y453F etc)23:01
de-factoso if maybe it did some journey through more species than only bats before?23:02
de-factoe.g. mice etc?23:02
de-facto.title https://link.springer.com/article/10.1007/s10311-021-01211-023:16
Brainstormde-facto: From link.springer.com: Should we discount the laboratory origin of COVID-19? | SpringerLink23:16
de-factobut afaik that is somewhat controversial yet interesting to read23:18
de-factoi think an honest and open debate over that without any tabu is what may have best chances to come closer to a plausible theory of origin23:19
BrainstormNew from r/WorldNews: worldnews: 100 million more children fail basic reading skills because of COVID-19 → https://is.gd/wmYh4r23:21
rpifanyea23:28
CoronaBot/r/covid19: Emergence of a SARS-CoV-2 E484K variant of interest in Arizona (83 votes) | https://www.medrxiv.org/content/10.1101/2021.03.26.21254367v1 | https://redd.it/mf2h5t23:41
de-factoanother convergent E484K?23:48
LjLde-facto, but the geopolitics and interests involved are too big to get an honest debate23:51
de-factogood point23:53
de-factoLjL, can i write you a PM?23:54

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