libera/##covid-19/ Wednesday, 2021-04-21

pwr22LjL: Hi, how's it going? I just heard that the UK variants have now started having the same immune escape change as in the Brazil and South African ones. That seems at least mildly concering 😧00:24
LjLpwr22, i haven't heard that, but i guess i had vague indications that E484K had started being around in the UK too, probably independent of SA... so yeah, that's meaningful although i'm not sure it automatically means the same immune escape (but i'm not sure what you're referring to either)00:25
BrainstormNew from r/WorldNews: worldnews: Also roaring back from pandemic: earth-warming emissions → https://is.gd/NukOAx00:26
LjLpwr22, what seems the most worrying to me at the moment is how India is spiking *real* bad (and probably much worse than the numbers are telling), how that is most likely due to a bad variant, and how we're reacting to that slowly or not at all... until a couple of days ago India was still not on the UK's flying "red list", and not on Germany's list of "countries with variants" either, meaning that at least the UK and Germany have cases from Indian00:26
LjLvariants now00:26
LjLi mean, i suppose technically we don't yet KNOW that the variant is very bad00:26
LjLwe only know that there is a variant, where the mutations are, and that at the same time, cases in India are spiking00:27
LjL"coincidence? i think not!"00:27
pwr22LjL: yeah E484K00:27
LjLor rather, i think that we shouldn't wait to *make sure* that it's not a coincidence. we should stop the flights!00:27
LjLwe should have stopped them weeks ago really00:27
pwr22Yeah00:27
LjLi don't understand how we are calmly affording to make the whole vaccination campaign go to waste just by letting people with potentially escaping variants fly here00:27
pwr22I actually thought that due to the successful vaccination campaign, that this winter the SA / Brazil variants would out compete the Kent ones here00:28
pwr22The Kent strain converging to the same increased resistance is surprising to me00:28
pwr22And even worse since it is still the most contagious one afaik?00:29
pwr22Boris was actually due to visit India I think, until recently00:29
pwr22LjL:  https://www.bbc.co.uk/news/health-5590062500:30
pwr22That's my source00:30
pwr22It's from ages ago though00:31
pwr22I have work colleagues who were part of the surge testing here in Bristol for that00:31
LjLpwr22, the thing is E484K has emerged independently multiple times, so at this point we should probably just take it as an inevitable act of convergent evolution, everywhere the virus is (unless we manage to STOP it almost completely with vaccinations, but that isn't happening at the required speed anywhere)00:35
BrainstormNew from The Lancet (Online): [Comment] Children in All Policies 2030: a new initiative to implement the recommendations of the WHO–UNICEF–Lancet Commission: In February, 2020, we published the WHO–UNICEF–Lancet Commission report A future for the world's children?1 The Commission called for a new global movement to put the health and wellbeing [... want %more?] → https://is.gd/pEHh0M00:36
LjLpwr22, on the potentially-plus side, if the same mutations are "inevitably" going to arise, that means that we could potentially predict them, and tweak vaccines even before they actually emerge00:37
LjLalthough predicting it would probably require performing gain-of-function research on the virus, in a lab, which is very much like what the Wuhan lab may or may not have been doing when the virus did or did not emerge from it :P00:37
LjLiow: it's risky00:37
LjLbut i'm not looking forward to lockdowns every bunch of months every time a new variant arise and we must rush to make vaccines for it, either00:38
BrainstormNew from StatNews: Pharma: STAT+: Congress probes Emergent’s ties to a key Trump official in wake of Covid-19 vaccine scandal → https://is.gd/7UWOrx00:47
BrainstormNew from Medical Xpress: Simple oral hygiene could help reduce COVID-19 severity, says study: COVID-19 could pass into people's lungs from saliva with the virus moving directly from mouth to bloodstream—particularly if individuals are suffering from gum disease, according to new research. → https://is.gd/eXLjzK01:07
LjLeek01:32
BrainstormNew from r/Coronavirus: Coronavirus: U.S. administers 213.4 mln doses of COVID-19 vaccines - CDC → https://is.gd/UL1cbQ02:58
finely[m]<de-facto "but there is no consensus to hav"> Cities that locked down fastest during the Spanish flu did better in terms of health AND economic outcomes. This may apply to our pandemic too.04:06
de-factoyes of course04:10
de-factoeconomy only works efficiently when it can allocate all resources in the most efficient way, yet the more citizens have to deal with the impact of the pandemic instead the fewer time and resources are available for economic growth04:15
de-factohence its not ( health OR economy ) its actually rather ( health AND economy ) obviously politicians too corrupted by dumb lobbyists still assume the mutually exclusive relationship04:18
finely[m]Today, Australia's federal government has finally pulled their head out of their arse and funded local manufacture of mRNA vaccines. At least a year too late. It will take at least a year to get up and running.04:19
finely[m]The same government who didn't want to pursue an elimination strategy (it was the state governments that achieved that), and still hasn't changed advice to reflect the fact airborne transmission is occuring.04:19
de-facto.title https://www.imf.org/external/datamapper/NGDP_RPCH@WEO/OEMDC/ADVEC/WEOWORLD/04:19
Brainstormde-facto: From www.imf.org: error parsing title ('NoneType' object has no attribute 'string')04:19
finely[m]<de-facto "hence its not ( health OR econom"> I guess its a question of whose health and whose money?04:19
de-facto"Real GDP growth" hint: pull the timeslider to 202004:20
de-facto.title https://atlas.cid.harvard.edu/countries/43/export-basket04:20
Brainstormde-facto: From atlas.cid.harvard.edu: The Atlas of Economic Complexity04:20
de-factocorrection: not ( health XOR economy ) but rather ( health AND economy )04:24
BrainstormNew from r/WorldNews: worldnews: EU regulator finds J&J vaccine has ‘possible link’ to blood clots → https://is.gd/sEnF8e04:32
BrainstormNew from r/WorldNews: worldnews: Carbon emissions to soar in 2021 by second highest rate in history: Global economies forecast to pour stimulus money into fossil fuels as part of Covid recovery → https://is.gd/c8fLpo05:03
-RSSBot[LjLmatrix- Recent Commits to links:master: Add EMA statements about blood clots with J&amp;J ( https://github.com/ljl-covid/links/commit/68e3a99ff607e74220de02487502c1830ed309ab )05:47
BrainstormNew from https://covid19.specops.network : ljl-covid: Add EMA statements about blood clots with J&J → https://is.gd/GIEMAg05:53
BrainstormNew from EurekAlert!: New insights on inflammation in COVID-19: Severe cases of COVID-19 can involve extensive inflammation in the body, and clinicians have wondered if this state is similar to what are called cytokine storm syndromes, in which the immune system produces too many inflammatory signals that can sometimes lead to organ failure and death. [... want %more?] → https://is.gd/ZT2OIK06:24
BrainstormNew from The Indian Express (Health): Feelings: ‘Hope for the best, prepare for the worst’: Gul Panag shares ‘cardinal rule’ amid pandemic → https://is.gd/QFZ9Ye06:34
BrainstormNew from r/WorldNews: worldnews: Covid wreaking havoc in India: 300,000 new cases and over 2000 deaths in past 24 hours → https://is.gd/8cCPVp07:15
CoronaBot/r/covid19: Government launches COVID-19 Antivirals Taskforce to roll out innovative home treatments this autumn (80 votes) | https://www.gov.uk/government/news/government-launches-covid-19-antivirals-taskforce-to-roll-out-innovative-home-treatments-this-autumn | https://redd.it/muygm208:09
BrainstormNew from The Indian Express: World: ‘We Were Left With Nothing’: Argentina’s misery deepens in the pandemic → https://is.gd/L3bBBl08:28
finely[m]My mistake, its a state government setting up mRNA vaccine production.09:09
finely[m]https://www.abc.net.au/news/2021-04-21/victoria-to-develop-mrna-covid19-vaccine-facilities/10008337209:09
BrainstormNew from The Indian Express: World: Europe has finally turned a corner on its Covid-19 vaccinations → https://is.gd/bKdqZa09:10
BrainstormNew from Medical Xpress: Environmental DNA and RNA may be key in monitoring pathogens such as SARS-CoV-2: Real-world disease and parasite monitoring is often hampered by the inability of traditional approaches to easily sample broad geographical areas and large numbers of individuals. This can result in patchy data that fall short of what researchers [... want %more?] → https://is.gd/USBYt009:41
BrainstormNew from The Indian Express: World: Thailand: Third COVID wave threatens plans to reopen tourism → https://is.gd/iBSBye09:52
BrainstormNew from Emma Hodcroft: @firefoxx66: Heute Abend, 20 Uhr CET: @DBinswanger (@RepublikMagazin) und ich werden über #SARSCoV2 sprechen:Wie ist die Situation jetzt? Wie sieht es mit Varianten aus? Warum ist Sequenzierung immer noch wichtig? 🧬🤔🇨🇭https://www.youtube.com/watch?v=pSYLAcdrYW0&t=0shttps://is.gd/AyIJUT10:02
BrainstormNew from Medical Xpress: Vaccine maker Valneva less hopeful of Europe-wide deal: French-Austrian vaccine developer Valneva said Wednesday it would "deprioritise" centralised talks with the European Commission to supply its coronavirus shot across the 27-nation EU, switching instead to "a country by country basis". → https://is.gd/se1khk10:13
BrainstormNew from EMA: What's new: Medicine: Human medicines European public assessment report (EPAR): Flucelvax Tetra, influenza vaccine (surface antigen, inactivated, prepared in cell cultures), Influenza, Human, Date of authorisation: 12/12/2018, Revision: 7, Status: Authorised → https://is.gd/X67dla10:34
BrainstormNew from StatNews: Pharma: Most Americans say they should be vaccinated before the U.S. donates Covid-19 shots elsewhere → https://is.gd/dxXMsl10:44
-RSSBot[LjLmatrix- Feed: Convocazione del Consiglio dei Ministri n. 14 ( http://www.governo.it/it/articolo/convocazione-del-consiglio-dei-ministri-n-14/16669 )10:51
-RSSBot[LjLmatrix- Feed: Consiglio dei Ministri n. 14 ( http://www.governo.it/it/articolo/consiglio-dei-ministri-n-14/16670 )10:52
BrainstormNew from The Indian Express: World: Israel to buy Covid-19 variant specific vaccine from Moderna → https://is.gd/O8Gb3S10:55
BrainstormNew from Medical Xpress: India Covid surge hits new record as oxygen runs short: India's brutal new COVID outbreak set records on Wednesday with more than 2,000 deaths in 24 hours as hospitals in New Delhi ran perilously low on oxygen. → https://is.gd/5eGIHK11:15
BrainstormNew from The Indian Express (Health): Food & Wine: Chef Saransh Goila shares list of COVID meal providers across 12 states, 25 cities → https://is.gd/u8Vb5E11:35
-RSSBot[LjLmatrix- Feed: Modifiche graduatorie finali procedura di selezione per lo sviluppo economico all’interno della Categoria A per il personale dei ruoli della PCM – Attribuzione parametri retributivi: A-F9, A-F8, A-F7, A-F6, A-F5, A-F3 e A-F2 ( http://www.governo.it/it/articolo/modifiche-graduatorie-finali-procedura-di-selezione-lo-sviluppo-economico-all-interno-della )11:42
-RSSBot[LjLmatrix- Feed: Modifiche graduatorie finali procedura di selezione per lo sviluppo economico all’interno della Categoria B per il personale dei ruoli della PCM – Attribuzione parametri retributivi: B-F7 ( http://www.governo.it/it/articolo/modifiche-graduatorie-finali-procedura-di-selezione-lo-sviluppo-economico-all-interno-0 )11:51
BrainstormNew from r/WorldNews: worldnews: Covid-19 in India: Why second coronavirus wave is devastating → https://is.gd/Jf7rXh11:56
greymanquit12:02
BrainstormNew from Retraction Watch: ‘Unfair and unsubstantiated’: Journal retracts paper suggesting smoking is linked to lower COVID-19 risk: A paper suggesting that smokers were significantly less likely than nonsmokers to contract Covid-19 has been retracted because the authors failed to disclose financial ties to … the tobacco industry.  The article, [... want %more?] → https://is.gd/Ki3bmD12:07
CoronaBot/r/covid19: Production of Sputnik V launched in Argentina (81 votes) | https://sputnikvaccine.com/newsroom/pressreleases/production-of-sputnik-v-launched-in-argentina/ | https://redd.it/muwcll12:11
BrainstormNew from Emma Hodcroft: @firefoxx66: And if you can't wait until 8pm, tune in at 4pm CET to @mpiib_berlin where I'll be speaking about a /non/-variant-of-concern & what we can learn from it!#SARSCoV2 → https://is.gd/tL2LiZ12:18
BrainstormNew from r/WorldNews: worldnews: A triple mutant variant of coronavirus has been found in India. Two of the three mutations make the virus immune towards any vaccine. → https://is.gd/19M38P12:50
CoronaBot/r/covid19: Inactivation of SARS-CoV-2 in chlorinated swimming pool water (80 votes) | https://www.biorxiv.org/content/10.1101/2021.04.19.440446v1 | https://redd.it/mv9bj013:41
BrainstormNew from The Indian Express (Health): Health: Taking care of Covid patients at home: Some simple dos and don’ts → https://is.gd/2uTuPZ14:02
BrainstormNew from Derek Lowe: @jonathanrockoff: RT by @Dereklowe: Pfizer has confirmed fake versions of its vaccine in Mexico and Poland. Dozens of people got the counterfeit shots, ⁦@JaredSHopkins⁩ and @Jose_deCordoba report.  https://www.wsj.com/articles/pfizer-identifies-fake-covid-19-shots-abroad-as-criminals-exploit-vaccine-demand-11619006403https://is.gd/6lNvuk14:23
de-facto[m]Damn.14:43
BrainstormNew from r/WorldNews: worldnews: New, antibody-resistant coronavirus variant discovered in Texas → https://is.gd/Jen7Lm14:44
de-factoits no good idea to buy vaccines from some shady drugdealer, rather trusting the official controlled distribution channels is much more safe14:59
de-factobtw another reason to invest into local production capacities15:01
de-factoi dont understand why we would not see modern vaccine factories appearing everywhere like mushrooms in the forest15:02
de-factopretty sure there are laws to force request licenses for production or such15:02
BrainstormNew from The Indian Express: World: Sri Lanka reports six cases of blood clots among AstraZeneca vaccine recipients, 3 dead → https://is.gd/WVLbJ515:04
BrainstormNew from Medical Xpress: Racial inequalities and COVID-19: Addressing the long-term impacts: It didn't take long for the world to feel the pandemic's impact on existing inequalities. A year after the arrival of COVID-19, however, and many of those outcomes have proven to be far more wide-reaching and devastating than anticipated, especially where race [... want %more?] → https://is.gd/e7oAPM15:15
BrainstormNew from StatNews: Pharma: STAT+: Pharmalittle: Pfizer identifies first counterfeit versions of its Covid-19 vaccine; top house Democrats investigate Emergent BioSolutions → https://is.gd/p4GYk215:25
BrainstormNew from r/WorldNews: worldnews: Fake COVID-19 vaccines have been discovered by Pfizer in Mexico and Poland → https://is.gd/GOwU8P15:35
BrainstormNew from The Indian Express (Health): Health: Oxygen requirement, vaccine, hospitalisation: India’s leading doctors answers all your questions on COVID-19 → https://is.gd/HLrhLF15:46
BrainstormNew from Politico: Airlines: France to lift coronavirus lockdown, quarantine travelers from India → https://is.gd/NxkSbN16:17
BrainstormNew from Politico: Commitments: Boris Johnson taps up vaccines boss for new Downing Street unit → https://is.gd/lQje0x16:27
BrainstormNew from Medical Xpress: US to hit 200 million vaccine doses target 'this week:' W.House: The United States will hit President Joe Biden's target of administering 200 million doses of coronavirus vaccines within his first 100 days in office by the end of this week, the White House said Wednesday. → https://is.gd/CTSzqO16:38
BrainstormNew from BMJ: Covid-19: Canada relaxes age limits on AstraZeneca vaccine as Ontario cases surge: Three weeks after restricting the AstraZeneca vaccine to people aged 55 and older, provinces across Canada have reversed course and expanded access to include anyone aged over 40, faced by surging... → https://is.gd/dJBrmW16:59
BrainstormNew from Medical Xpress: SARS-CoV-2: Infection induces antibodies capable of killing infected cells: Drawing on epidemiological field studies and the FrenchCOVID hospital cohort coordinated by Inserm, teams from the Institut Pasteur, the CNRS and the Vaccine Research Institute (VRI, Inserm/University Paris-Est Créteil) studied the antibodies induced [... want %more?] → https://is.gd/Mz1K1M17:09
BrainstormNew from ClinicalTrials.gov: (news): A Study to Evaluate the Efficacy, Safety and Immunogenicity of SARS-CoV-2 Vaccine (Vero Cells), Inactivated in Healthy Adults Aged 18 Years and Older (COVID-19) → https://is.gd/qZVze417:30
BrainstormNew from LitCovid: (news): Small but nimble: measures taken to face the COVID-19 pandemic in small French military hospitals. → https://is.gd/lMoWkE17:51
BrainstormNew from ClinicalTrials.gov: (news): A Clinical Observational Study of SARS-CoV-2 Specific CD8 T-Cell Responses to COVID-19 Vaccines in Humans → https://is.gd/NRtfrl18:01
-RSSBot[LjLmatrix- Feed: Colloquio telefonico tra il Presidente Draghi e il Presidente Macron ( http://www.governo.it/it/articolo/colloquio-telefonico-tra-il-presidente-draghi-e-il-presidente-macron/16675 )18:02
BrainstormNew from WebMD: Strides Against HIV/AIDS Falter During Pandemic: Public health resources have shifted from one pandemic to the other, and experts fear steep declines in testing and diagnoses mean more people will contract HIV and die of AIDS. → https://is.gd/fYEZRn18:22
BrainstormNew from Medical Xpress: FDA inspection found problems at factory making J&J vaccine: The Baltimore factory contracted to make Johnson & Johnson's COVID-19 vaccine was dirty, didn't follow proper manufacturing procedures and had poorly trained staff, resulting in contamination of material that was going to be put in the shots, U.S. regulators said Wednesday. → https://is.gd/s9NOIm18:42
BrainstormNew from BMJ: Covid-19: Is the UK heading towards mandatory vaccination of healthcare workers?: Why is mandatory vaccination in the news?Leaders at Chelsea and Westminster Hospital Foundation Trust have been discussing making covid-19 vaccination a contractual requirement for all staff, in a... → https://is.gd/yPZ35l18:53
BrainstormNew from StatNews: Pharma: STAT+: FDA issues scathing report of Emergent plant responsible for contaminated Covid-19 vaccines → https://is.gd/5vhVHJ19:03
BrainstormNew from Derek Lowe: @Dereklowe: This is an excellent, detailed look at Novavax and the difficulties they've been having producing their vaccine at scale. Everyone wondering "Why don't we just let everyone make all the vaccines?" should read it:https://endpts.com/as-fears-mount-over-jj-and-astrazeneca-novavax-enters-a-shaky-spotlight/https://is.gd/YV9bSt19:14
BrainstormNew from WebMD: J&J Pause Did Not Upend Vaccine Confidence: Poll: A nationwide poll of 1000 Americans also finds the gap in overall vaccine beliefs between Republicans and Democrats could be narrowing. → https://is.gd/P03is619:24
GonzaloCastilloi'm contraired corona20:49
-RSSBot[LjLmatrix- Feed: Comunicato stampa del Consiglio dei Ministri n. 14 ( http://www.governo.it/it/articolo/comunicato-stampa-del-consiglio-dei-ministri-n-14/16679 )21:02
de-facto.title https://www.bundesregierung.de/breg-en/news/nationwide-emergency-brake-188913621:06
Brainstormde-facto: From www.bundesregierung.de: Infection Protection Act - nationwide emergency brake21:06
BrainstormNew from Medical Xpress: Italy to begin easing Covid restrictions: The Italian government said Wednesday it plans to gradually lift COVID-19 restrictions from next week, with restaurants and movie theatres set to reopen. → https://is.gd/npSvlO21:08
LjLde-facto, ↑ look we're stupid too21:28
LjL%title https://www.yahoo.com/news/trump-admin-awarded-firm-1-083136627.html  :\21:30
BrainstormLjL: From www.yahoo.com: The Trump admin awarded a firm $1.3 billion to make Covid vaccine syringes. Where are the syringes?21:30
BrainstormNew from Scientific American: India's Massive COVID Surge Puzzles Scientists: Workers prepares to fill medical oxygen cylinders for hospital use on Covid-19 coronavirus patients on the outskirts of Jabalpur on April 18, 2021. → https://is.gd/ap5DD821:40
de-factoyay22:19
de-factoactually above "emergency brake" is an alibi actionism, for example curfew: from 22:00-05.00 and with lots of exceptions like, uhm going for a walk till 24:0022:20
de-factothats a compromise so far on the side of the pathogen that it probably will not make any difference22:21
BrainstormNew from Virological.org: Latest posts: Genomic Surveillance of SARS-CoV-2 in the State of Rio de Janeiro, Brazil: technical briefing: Genomic Surveillance of SARS-CoV-2 in the State of Rio de Janeiro, Brazil: a technical briefing Luiz G P de Almeida¹, Alessandra P Lamarca¹, Ronaldo da Silva F Jr¹, Liliane Cavalcante¹, Alexandra L Gerber¹, Ana [... want %more?] → https://is.gd/jl2gb222:21
BrainstormNew from r/WorldNews: worldnews: India's second Covid wave hits like a 'tsunami' as hospitals buckle under weight → https://is.gd/U6vK2x23:03
LjLthat Scientific American article about India has no steadfast conclusions but every possibility is pretty awful :(23:08
BrainstormNew from Medical Xpress: UAE warns of restrictions for unvaccinated as doses near landmark: The UAE announced Wednesday it had given nearly 10 million vaccine doses, equal to one for every resident, after warning that those who remained unvaccinated would face restrictions on their movement. → https://is.gd/xUzgRm23:13
de-facto.title https://www.ema.europa.eu/en/news/covid-19-vaccine-janssen-ema-finds-possible-link-very-rare-cases-unusual-blood-clots-low-blood23:30
Brainstormde-facto: From www.ema.europa.eu: COVID-19 Vaccine Janssen: EMA finds possible link to very rare cases of unusual blood clots with low blood platelets | European Medicines Agency23:30
de-facto"At its meeting of 20 April 2021, EMA’s safety committee (PRAC) concluded that a warning about unusual blood clots with low blood platelets should be added to the product information for COVID-19 Vaccine Janssen. PRAC also concluded that these events should be listed as very rare side effects of the vaccine."23:31
ArsaneritWhat is PRAC?23:42
ArsaneritOh, it says.  Sorry.23:43
ArsaneritI need to sleep.23:43
ArsaneritGoodnight.23:43
de-factogn823:44
CoronaBot/r/covid19: The Origin of COVID-19 and Why It Matters (83 votes) | https://www.ajtmh.org/downloadpdf/journals/tpmd/103/3/article-p955.pdf | https://redd.it/mvl85423:46
BrainstormNew from r/WorldNews: worldnews: India: Good news from India, Covid-19 Vaccine Developed by Bharat Biotech Neutralizes all the Coronavirus Mutations → https://is.gd/7DI7wc23:55

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