libera/##covid-19/ Saturday, 2021-05-15

LjLwaitingformagic, let's just keep it in the channel, it's basically what it's there for!00:00
LjLi just think that most European governments have consistently done things that have made the virus situation worse00:00
LjLeither in the name of economy or with arguments like "we're being careful and doing things slowly" (except not really, or the wrong things)00:00
LjLone recent example has been the Indian variants being imported00:01
LjLit might have been inevitable, but one should at least *try* to avoid it... instead, it took weeks or months before countries decided to actually stop flights from India00:01
waitingformagicIt's difficult to shut the border of the entire EU00:01
LjLit might be difficult to completely seal it, but it's definitely possible to at least *try* to stop entry00:02
LjLthat is, to say, okay, from now on, sorry but people from India cannot enter the EU (or the UK)00:02
LjLwhich has been done, now, so it *is* possible00:02
LjLbut it should have been done... a lot sooner00:02
LjLnow the Indian variant is already rising exponentially and doubling every week in the UK00:03
LjLjust as Boris Johnson announces that it may put the plans to reopen in jeopardy, other countries like Italy reopen to people from the UK (which previously required a quarantine to enter). again, self-defeating, in the name of tourism or whatever00:03
LjLand while the UK has a lot of its population vaccinated, so hopefully the Indian variant won't cause *too* much of a problem, that's not true of Italy00:04
LjLit's not true of any part of the EU, so it's suicidal to open things up just when vaccine uptake is still too low and a new, likely much more infectious, variant is coming in00:04
waitingformagicIt was always my understanding that the vaccine was to prevent you the individual from becoming sick to the point you'd choke out the health system00:05
waitingformagicnot the it would stop the transmission of the virus00:05
waitingformagicis that a correct assumption ?00:05
waitingformagicif it is then your point is valid00:06
LjLno, it's not a correct assumption00:08
waitingformagicthen I require enlightenment my friend00:09
LjLauthorities and experts repeatedly warned that the vaccine *may not* stop the transmission, or not fully, because we didn't have clear evidence that it would, and because that was the safe default00:09
LjLbut at the same time, due to how vaccines work, it was extremely likely that the vaccines *would* have stopped or at least severely hindered transmission00:09
LjLthe details are hazy, and for example AZ may behave differently from Pfizer in this respect, but there is enough tentative evidence now to say that vaccine do stop the transmission, for the most part00:10
LjLbut also such statements need to always be qualified: do they stop it for all the variants in circulation, or just the prevailing one?00:10
waitingformagicmy point exactly00:10
LjLright now, we know that AZ doesn't stop the South African variant, for example (B.1.351)00:10
LjLwe "seem to be hopeful" that the the vaccine works well against the Indian variant (B.1.617.x), but we don't have studies making that certain00:11
waitingformagicbetter to say , keep the distancing and masks on everyone , this fights not over00:11
LjLand the variant does seem to have an infection advantage over the "old" B.1.1.7 variant, so clearly it's an important unknown00:11
LjLwell, they do say that00:11
LjLi just don't think it's enough00:11
LjLpeople will do what people will do, but the big difference, if any, will be made by bigger policy decisions00:12
waitingformagicpeople are class A1 fucking idiots00:12
waitingformagicthat's a given00:12
LjLand as i said, the UK has a lot of its population vaccinated, but the EU doesn't, so the EU should be extremely careful about importing any variant that may be more infectious or more dangerous or more anything than what we already have00:12
waitingformagicI agree00:12
LjLi will keep washing my hands and wearing my mask and mostly staying home in the meanwhile, sure00:13
waitingformagicWelsh First Minister today said to paraphrase - While its not illegal for you to take a foreign holiday, of ALL the years to NOT do it , this is the one00:13
waitingformagiccommon sense00:14
LjLit does seem like common sense, doesn't it? but as they say, it's not so common00:14
waitingformagicsense wasn't dished out evenly it would appear00:14
LjLpeople are eager to have holidays and stuff and many don't really see the danger, still (or even think "there was little danger before, now we're vaccinated, there's virtually none")00:14
waitingformagicI see no rush to foreign shores THIS year00:14
waitingformagicnext year maybe00:15
waitingformagicMAYBE00:15
LjLhave you listened to Boris Johnson's press conference?00:15
waitingformagicNo00:15
LjLi'm not usually too eager to make people listen to Boris Johnson00:15
waitingformagicwas it like being hit with a public school rugby tackle00:16
LjLbut i am baffled by the disconnect between the severity of what he's saying, and the fact the EU is reopening00:16
LjL%title https://www.youtube.com/watch?v=GI3PTH_GiAc00:16
BrainstormLjL: From www.youtube.com: Prima di continuare su YouTube00:16
waitingformagicthe UK spends a fuck ton of money in the sun every year00:16
waitingformagicglobal warming will fuck that00:17
waitingformagicbut thats a different channel :)00:17
waitingformagicback in 200:17
BrainstormNew from Reddit (test): Covid2019: United States announces $7 Billion to Hire and Train Public Health Workers in Response to COVID-19, $400 million invested to Launch Public Health AmeriCorps, $3 billion to 'Create a New Program to Modernize the Public Health Workforce'. → https://is.gd/auGrSo00:18
waitingformagicback00:21
dTalLjL: I reckon Boris had an epiphany when he said that opening up was gonna cause deaths but they were gonna do it anyway00:22
waitingformagicI read in passing a US state was going to offer a $1million to  5 people at random for having the vaccine00:22
dTalhe's realized he can *do* whatever, as long as he makes soft clucking noises of warning00:22
dTaland people will ignore him, and then he can say "told you so"00:23
LjLand he's got antibodies!00:23
LjLoh yes that is a thing00:23
LjLcovering ass by being like "hey the people didn't listen to out words of caution"00:23
LjLthat's why i'm annoyed by these policy actions more than by people behaving in silly ways00:23
dTal(but also encouraging people to ignore the words caution)00:23
LjLbecause people *will* behave in the ways they can be *predicted*, as groups, to behave00:23
LjLbut the policy actions cannot take that as an excuse to be sloppy00:24
LjLwell, they can, but it gets on my nerves00:24
waitingformagicthats not a covid discussion though is it00:24
waitingformagicits a freedom discussion00:24
waitingformagicdo you think government should compel you by force to comply00:25
waitingformagicor00:25
waitingformagicyou're an individual who gets to act within guidelines00:25
waitingformagicor00:25
LjLi think that boat has sailed, governments including the UK one have already compelled people to observe lockdowns, which are sets of rules that would normally be judged unconstitutional just about anywhere sane00:25
LjLanyway that's not even what i'm talking about00:25
waitingformagicpfff you could break lockdown in the UK easily00:26
LjLwhat i'm talking about is you can't keep flights from India going, while later blaming people for not observing your guidelines00:26
waitingformagicAustralia there were cops at the end of the road stopping you00:26
LjLif you're Italy you can't keep flights from Britain going, just because you know you can later blame people for not being "cautious" as you told them to be00:26
dTalTo be fair, as fun as it is to rag on Boris, he's shooting pretty straight in that breifing00:26
dTal*briefing00:26
waitingformagicI concede my point to rest to yours being the discussion00:27
LjLdoes that make a "philosophical" difference waitingformagic? it sure makes a practical difference in how effective the lockdowns are, but in both cases, you are legally compelled to comply00:27
waitingformagicsee above00:27
waitingformagicopen borders don't work00:27
waitingformagicto return to the point of your discussion00:27
LjLdTal, yeah that's why i say it's sobering, or rather, befuddling, to listen to the gravity of what he says while seeing the contrast of my country reopening in many ways including to UK tourism00:27
waitingformagicremember the early days00:27
waitingformagicNZ wow00:28
waitingformagiceasy though as they are the arse end of the world00:28
waitingformagicI have people in Western Australia - borders to the rest of AU shut - cases in the handful and traced00:29
waitingformagiceconomy, who knows what the cost is00:29
LjLyes, and sure, those are islands, that does make things easier, but uh, the UK is also an island, and the EU/Schengen, if it acted together, could be not quite an island but less messy than it is now00:30
waitingformagicEU isn't an Island00:30
waitingformagicUK is00:30
dTalI'm not really sure how relevant the island thing is00:30
waitingformagicbut so massively interconnected to the rest of the world that the water is irrelevant00:31
waitingformagicyes to your point00:31
dTalthere's tons of unstoppable travel, in this globalized world00:31
dTalya00:31
dTalthere's literally an underwater land bridge to France00:31
waitingformagiceurotunnel00:32
dTal*chunnel00:32
waitingformagicstar00:32
waitingformagic:)00:32
LjLde-facto, https://youtu.be/GI3PTH_GiAc?t=55900:32
waitingformagicthat thing00:32
waitingformagicfunny story00:32
dTalI took the Eurostar once00:33
waitingformagicgoogle - Wellington fear of French invading through tunnels00:33
waitingformagic:)00:33
LjLthe tunnel was planned to be built like one century before it actually ended up being00:34
dTalbusiness class, even. So weird to think that London->Paris is so damn quick in reality, if you've got the cash00:34
LjLwhen they started building it, they actually found the assay tunnels that had been excavated a century prior00:34
waitingformagicyes00:34
LjLbut ultimately the project was abandoned mainly due to war-related fears, indeed00:34
dTalI thought it was beyond the engineering of the time00:34
waitingformagictunnelling was a proper art00:34
waitingformagicnoo00:34
LjLdTal, maybe it would have turned out to be, but i don't think that's why it was dropped00:35
waitingformagicthey knew how to build stuff00:35
dTalthey figured out how to do underwater tunneling, but at that scale?00:35
waitingformagicThames00:35
dTalyeah I watched a history channel thing on it back when it was good :D00:35
waitingformagicSiene00:35
rpifani love the eurostar00:35
rpifani too took the business class00:35
dTalsomething about being inspired by the shield worm00:35
rpifanwas so lovely00:35
rpifani wish the ride was longer00:36
dTalrpifan: it's good innit00:36
waitingformagicThe Spice00:36
rpifanthose free breads00:36
rpifanand tea00:36
dTalthe food was fantastic00:36
rpifanlol00:36
dTali got fed salmon00:36
rpifanclearly dTal and i are of the same opinion00:36
rpifanthe only issue was the tea cups were tiny00:36
rpifancouldnt get a proper cup of tea00:36
dTalyou got the sense that the french were in charge of catering00:36
waitingformagiccheck dTal the Champaign Charlie with his salmon00:36
waitingformagic:D00:36
dTalexcellent food, lame tea00:36
LjLbut really, i'm scared again. that sharp rise of cases in Bolton, only in unvaccinated-age people... https://www.youtube.com/watch?v=GI3PTH_GiAc   YIKES for any country that doesn't have the UK levels of vaccine deployment. can i like call the president or something? they never listen to me on twitter :(00:36
rpifandTal, where do you live00:37
rpifanwell the eurostar does use tgv train sets00:37
dTalengland00:37
waitingformagicEngland00:37
rpifanand the eurostar is partially owned by the french00:37
waitingformagichad your jab yet dTal ?00:37
waitingformagicAZ here00:37
dTalnope, too young and sprightly for .gov to give a crap00:38
rpifandTal, i wanan go back ot the uk00:38
rpifani havent been since i moved to europe00:38
rpifando you know when they will ope tnehborder00:38
waitingformagicI got the AZ00:38
rpifani got friends i wanna visit in manchester00:38
waitingformagicsore arm , dizzy lethargy for meh 12hrs - less than a proper hangover00:39
waitingformagicright as rain00:39
dTalI know someone who works in a factory than makes AZ00:39
BrainstormNew from The Lancet (Online): [Comment] Convalescent plasma in patients hospitalised with COVID-19: As the COVID-19 pandemic continues, researchers continue to search for effective treatments. The often unpredictable disease course of COVID-19 creates a substantial challenge for clinical researchers when identifying ideal patient populations who might [... want %more?] → https://is.gd/yzkvnl00:39
waitingformagicdo they piss in it ?00:39
waitingformagic:)00:39
dTalno her job is to make sure no one pisses in it00:39
dTalas I understand it, anyway, it's all terribly abstract00:40
waitingformagichehe00:40
rpifanlol00:40
waitingformagicI had it at 1100hrs day1, fine until 4am weird fever dreams and then dogshit hangover day - 1800hrs meh could drive a car00:41
rpifani really want tehc hina one00:42
rpifanive set my sights on that00:42
waitingformagicget the AZ one00:42
rpifannah00:42
rpifantoo risky00:42
waitingformagictoo young ?00:42
waitingformagicI mean the odds are weirdly massive00:43
waitingformagicBUT00:43
rpifanive got a lot of medical complicatiosn00:43
waitingformagicfair go mate00:43
dTalpfizer for me plz00:44
waitingformagicmy motherinlaw got that00:44
rpifani really just want the traditional inactivated kind00:44
waitingformagicright as rain00:44
rpifanlike every other vaccine ever made00:44
waitingformagicmy Sister in Austria got AZ00:44
waitingformagicspinning head puking weirdo00:44
waitingformagicwhen she had the vaccine though00:45
dTalbut when the Bill Gates digital rapture comes you won't have a microchip rpifan00:45
dTalyou'll get left behind00:45
waitingformagicsorted her right out :)00:45
rpifandTal, its ok ill get the chinese 5g00:45
waitingformagicpmsl00:45
rpifanwaitingformagic, sister in austria and brother in the uk?00:45
waitingformagicI'm the Brother00:45
waitingformagicshes' a teacher00:46
rpifanyea i know i was asking00:46
rpifanah00:46
rpifani knew a girl from manchester who taught english in austria00:46
waitingformagicshe's in her 50's00:46
rpifanshe was taking german classes with me00:46
rpifanonline00:46
waitingformagicand was worried about the fact she had to go teach with people who gave zero fucks about the virus00:46
waitingformagicearly on00:47
rpifanwell at least she is osterreich my sister is a teacher in the US00:47
rpifanand boy did they get fucked00:47
rpifanand she teachs the younger ones00:47
waitingformagiceventually the politicians realized the teachers were about to riot00:47
waitingformagicso within days - get in for vaccine00:48
waitingformagicjab00:48
waitingformagicdone00:48
waitingformagicAZ00:48
waitingformagicthing is this00:48
waitingformagicthey told them there would be side effects :)00:48
waitingformagicof course the fucking teachers take a day off sick :D00:48
waitingformagicwork shy fuckers00:48
LjLi don't think the world is ending because someone takes a day off from vaccine side effects00:49
LjLalso not everybody has the same reactions to it and among the 6.5 people i know, i know someone who's had a day of much worse effects than what you described00:49
waitingformagicI don't think levity is taking a hit for me making a joke at teachers swinging the lead LjL00:50
waitingformagicits a piss take00:50
* LjL shrugs00:50
rpifanwell in the us teachers got 0 protection00:50
rpifanand they have no union00:50
waitingformagicUK the teachers Unions went mad - demanding it00:51
waitingformagicbut the govt plan was - most vulnerable first00:51
rpifanyea i think some states in the us do have a union but my sister does not00:51
waitingformagicso if you were a vulnerable teacher BOOM done00:51
waitingformagicyoung teacher - you can take your spot after grandma and diabetic Brad00:52
waitingformagicseems to have worked00:52
waitingformagicwe'll see though00:52
rpifani hope the border opens i really wanna go back00:52
rpifaneat some greasy fast food00:52
waitingformagicwhere you from from rpifan ?00:53
waitingformagicand are you a raspberry pi fan ?00:53
rpifanim from your former colony00:53
rpifanthe big one00:53
waitingformagicThe United States of America00:54
Win7ineIndia00:54
rpifanhis royal majesties colonies00:54
rpifanthe 13 of them00:54
waitingformagicnot my colony my friend my family is Irish00:54
waitingformagic:)00:54
rpifanno problem we are still related00:55
waitingformagicwe're both sons of empire00:55
rpifanthe person who liberated my fathers country from the spain was an irish man00:55
waitingformagicjesus wept we're related00:55
waitingformagicI feel a tune coming on and a bottle opening00:56
waitingformagic:)00:56
waitingformagichow are things where you are ?00:56
rpifanv00:56
rpifanhttps://en.wikipedia.org/wiki/Bernardo_O%27Higgins00:56
rpifanhere you can see him in his full irish glory00:57
waitingformagiche's far too much hair to be one of my tribe00:57
rpifanmany irish ppl dont een know about him00:57
rpifanyet he was one of the most important ppl in the whole history of latin america00:57
rpifancounty sligo apparently00:57
waitingformagicha Cork00:58
waitingformagicthose Sligo cunts00:58
waitingformagicnot to be trusted00:58
waitingformagicwhen I say Cork00:58
rpifani assume u r from the south00:58
Win7inethis channel was COVID related?00:58
waitingformagicI was born in London00:58
waitingformagicWine700:58
waitingformagicyou raise a valid point00:58
rpifanfair enough00:59
BrainstormNew from NPR: What The New Mask Guidance Means For Unvaccinated Kids — And Their Parents: I'm fully vaccinated, but my kids aren't. Can I safely take off my mask? Do my unvaccinated kids have to keep masking in public? → https://is.gd/BGUxk101:00
Win7ine@rpifan latin america was taken from its inhabitants by brute force just the same as north america, what importace does your ancestor have in this?01:02
rpifanim latin american01:02
rpifanmy ppl were taken by the europeans01:02
rpifaneven genetically im about half native half white01:02
waitingformagicWOAH DUDES01:03
waitingformagicCOVID01:03
waitingformagic!01:03
waitingformagic:D01:03
LjLyes, this channel is COVID-related; yes, i'm fine with occasional offtopic discussion; but if you have to make it into a race argument and who-colonized-whom, then my god back to COVID01:03
Win7ine@rpifan i read soemthing about ireland and irish in your corner ...01:04
Win7ineThe Empire01:05
waitingformagicLjL called it01:06
waitingformagicback on topic chaps01:06
Win7ineReminds me of the "EXPATS" ... everyone lese is an immigrant or emmigrant01:06
Win7ineWhatever suits whenever right?01:07
Win7ineShame is the ONLY hope!01:08
de-factoso Boris saying Bolton and Blackborn are B.1.617.2 hotspots, why on earth does he not restrict all traveling and establish a perimeter around it without informing people in advance about such intentions01:08
de-factoand then just redirect enough vaccines to get everyone there vaccinated and isolate the infected ones out of their homes in separate hospitals?01:08
BrainstormUpdates for Argentina: +18221 cases (now 3.3 million), +599 deaths (now 69853) since 23 hours ago — India: +1437 deaths (now 262317) since 16 hours ago01:09
LjLde-facto, because that would be cruel and hypocritical after he still allowed travel from India despite knowing about the variants there for a long time...?01:09
de-factoi dont care if it would be considered cruel, i only care that it is contained01:09
LjLwell i care01:09
LjLi don't agree with the fallout being on the people when the mistakes are at the government and policy level01:09
Win7ine@de-facto because Boris has not got your number nor have you got his01:09
LjLas i was saying01:09
rpifanbolton?01:10
de-factoi consider it cruel to put the success of the UK people into jeopardy just by allowing it to spread again01:10
de-factoits the job of the government to prevent such things, even if it made mistakes in the past01:10
de-factoand it seems they do know where it is located, hence its their job to use that knowledge to contain it01:11
rpifani really doubt the uk will backtrack01:11
LjLwe also know at the Europe level that it's located in the UK and yet we're opening up01:11
rpifanunless there is a new catastrophe01:11
Win7ine@de-facto how do you measure success, by deathrate per total inhibitants? That is a disaster compared to others01:11
rpifanfrench has also started to open01:11
LjLthe UK won't have a catastrophe with this because they have nearly enough vaccines deployed01:12
rpifanthey plan to allow americans in01:12
de-factothe fallout would be on far more people than those localized hotspots if not acted accordingly to the information available to them01:12
LjLthe EU doesn't, so how about we tell our governments that01:12
LjLde-facto, so maybe we should kill the people in those places because otherwise they might escape if they discover the plan to isolate them01:12
LjLby which i mean, there are compromises always, including on drastic sudden and surprise quarantines01:13
de-factoenforce them to stay until its under control, and yes with weapons if necessary01:13
LjLoh god01:13
de-factoevery compromise works in favor of the pathogen reproduction, we have seen that again and again01:14
de-factoand as long as its spreading with R>1 its not under control01:15
de-factoi bet most people would behave sane and participate in collaboration with a lockdown, but if some think they should behave selfish and quickly leave the area before its shut down (as seen before London went into lockdown), they should be prevented from doing so01:16
de-factohence it should not be announced in advance but they just should go ahead with it in secret over night or such01:16
de-factothen concentrate all resources on exploiting its still localized there, increase tracing and tracking capacities, isolate identified cases outside their social circles until they are not infectious anymore, of course help the people as much as possible and also progress with vaccinations in such areas as fast as possible01:18
de-factothat would make it as difficult as possible for that variant to spread, hence possibly gain enough time with their national vaccination campaign to progress far enough to also prevent the national spread of it01:19
de-factoits all a question of probabilities, a race against time, the while exponential pyramid is based on those few initial cases of that VoC, hence every control imposed in it now has exponentially amplified effects on the future01:19
de-factothe time to act is not, the window closes with numbers increaseing and people traveling around in the whole country01:20
de-factodo you think many people want to stay in those cities Boris announces during his speeches there?01:20
Win7ineInternational spread can only be countered by achieving timed inocculations all over the world at once, putting aside greed and all political nonsense01:22
de-factoif they got relatives in another city, well maybe they just decide to leave that place to stay with their friends or relatives in another place: exporting the VoC into many more places and then the advantage of it being localized in smaller clusters is lost01:22
de-facto100% ack, and also preventing traveling as much as possible01:22
Win7inefor once the world need to collaborate in the name of humanity and not politically incetivated economic greed01:23
de-factothat is very true, we need much more solidarity especially with those countries not producing their own vaccines and not having a healthcare system that can deal with their load of covid cases01:25
de-factoand we have to do it now, all countries worldwide need to rise immunity against it simultaneously and as quickly as possible01:26
Win7ineWhat do you know about vaccine production ... most of the "Oxford" is produced in India yet they were exporting most of the produce to the UK!01:28
Win7ineThe production is a greedy setup, controlled by corporations and paid for by tax payers01:28
Win7ineGovermnets are mere puppets in the game01:29
de-factoState Serum Institute (India) is (was?) worlds largest vaccine manufacturer01:29
de-factoat least for the viral vector ones and similar technology01:29
de-factoafaik not for mRNA01:29
Win7ineTHer are only two mRNA, the BionTech and the MOderna, all else is Vector and second class01:30
de-factohttps://www.unicef.org/supply/covid-19-vaccine-market-dashboard01:31
de-factoand soon also CureVac would be the third mRNA01:31
Win7ineway behind that CureVac, BionTech are setting up manufacturing in Germany to gain in dependence from  Pfizer as a mass producer01:33
BrainstormUpdates for Brazil: +85536 cases (now 15.5 million), +2706 deaths (now 432628) since 18 hours ago — Dominican Rep.: +1059 cases (now 275378), +5 deaths (now 3565) since a day ago01:33
de-factoBioNTech was the developer of BNT162b2 and producing from begin on, they gained more production capacity now, but of course do produce together with Pfizer and many others in international collaboration01:35
de-factoafaik CureVac tries to build up upon an all European supply chain, while still working on achieving their approval, so hopefully they are ready in a month or so? afaik their production facilities are already running01:36
de-factoi guess its quite difficult when relying on supply chains that source parts of their products in USA and them having wartime export bans on some of such products01:37
Win7ineBionTech had a massproduction agreement with Pfizer since their own capacity is/was mediocre as they are a reserach facility and not a production setup.01:37
de-factothen it probably is of great advantage to work together in a collaboration with an American company such as Pfizer01:38
Win7ineSame of Oxford, they are a University Research branch, AstraZeneca is the production partner.01:39
LjLexcept i understand Oxford was originally going to be a "free for all" (i.e. patent waiver for any company that wanted to produce it), but then somehow AstraZeneca got the exclusive01:40
LjLand... i would say that hasn't turned out to be a very good thing, at least not for the EU01:40
waitingformagicHello All01:40
waitingformagiccan I ask01:40
Win7ineBionTech wil eventually with their planned setup detach from Pfizer in near future and produce in Germany.01:40
waitingformagicwhat's the point of this discussion ?01:40
waitingformagicsorry01:40
de-factoyes its always like that 1) Publicly funded research (Universities etc) 2) Startup also getting publicly funded developing a product 3) Big Pharma going for the most profitable products while scaling up01:40
waitingformagicweary traveller01:41
LjLde-facto, but like it or not, production at scale (at a scale of 8 billion ideally!) is the major road obstacle to this whole thing01:41
Win7ine@LjL how do you think any of the jab are mad, free for all, some manufacturer need to make it in the tens of million doses, Oxofrd University is not the place for that01:42
LjLthere have been many vaccines ideas, a few worked, and there are probably many still in research that *will* work. but production at scale?01:42
de-factoLjL, yes scaling is the most important thing right now01:42
LjLWin7ine, what i'm saying is that my understanding was that Oxford would not get into an exclusive agreement with AstraZeneca, but instead, they would waive the patent, and any company with the capacity to produce the Oxford vaccine at scale would have been legally entitled to do so01:43
de-factowe need production rates to go up massively, they are not producing nearly enough to satisfy the demand of of the most rich countries, let alone all the others (the majority)01:43
Win7ine@waitingofrmagic Oh sorry , fogot the old muble about the Irish saving Latin America01:43
waitingformagicI wouldn't know about that01:45
Win7ine@LjL dream on ... even the creators of the vaccines BionTech and Oxford are too weak to dictate how things go as corporations throw big monies at them to shut them out of such decisions01:45
waitingformagicSon of empire here01:45
waitingformagicwasn't my term old fruit01:46
Win7ine@waitingformagic the Empire is Down, you merely have a little island left called the Great B, soon split as the Scots will depart from said empire too01:46
LjLWin7ine, well i'm not dreaming, i'm just saying it's my understanding that it was originally announced this way, then indeed "big money" somehow changed the plans01:48
LjLcan we stop with these jabs about empire and so?01:48
de-factobtw those numbers in UK, showing that in places with B.1.617.2 the increase mainly happened in the young, that MAY be an effect of vaccine protecting the elderly, but with such small and localized numbers, it also MAY just be because of founders effect, the young and the elderly not mixing enough and the new mutant arriving in the young01:48
LjLwe were talking about COVID, i'm not sure i can convincingly tell waitingformagic what the "point" of the conversation was, but it was very much a COVID-specific conversation01:49
Win7ineAnnounced because of public monies being poored into said opeartions, some scrutiniy is not existent01:49
waitingformagic@LjL loud and clear01:50
LjL(also guys, this is not twitter, nicknames will be highlighted just as easily - or more easily - without prepending @ to them)01:51
Win7ineWho in this round had a jab yet?01:53
BrainstormNew from r/WorldNews: worldnews: Military head of Canada’s vaccine rollout steps aside amid investigation → https://is.gd/M5fTdS01:53
* Win7ine slaps waitingformagic around a bit with a large trout01:53
waitingformagicI've had a Jab01:54
waitingformagicwho else01:54
Win7ineThat explains it all01:54
LjLno jab here, my parents have had one01:55
de-factoBoris was just asked about increasing vaccinations in hotspots and replied with bla bla, hence its not his intention to contain this while its still in hotspots01:56
waitingformagicjesus wept you're going to worry yourselves into an early grave01:56
waitingformagicget the jab01:56
LjL?01:56
LjLi cannot "get the jab"01:56
LjLthere is a queue to be respected01:56
de-factoi wish i could get one too, yet i cant01:56
waitingformagicgood lads thats the spirit01:57
de-factomy parents got 1st dose of BioNTech01:57
de-factothere is just not produced enough to satisfy the demand yet01:57
LjLi will be able to book my jab after 27 May01:57
LjL(no idea when the jab will be *given*, though)01:57
waitingformagicUK ?01:58
LjLno01:58
waitingformagicgood luck01:58
LjLthanks01:58
waitingformagicno I mean it01:58
waitingformagicIrish wish luck01:58
Win7ineHad the jab, AstraZ, it took me out, 4 days of agony - dread the second due.01:59
LjLi think we'll have better luck if i somehow convince my health minister to ditch their plans to allow unrestricted flights from the UK01:59
LjLWin7ine, if it helps the anecdotal evidence (well, and some of the trial evidence) is that with AZ, the second shot tends to be less bad (unlike with BNT)02:00
waitingformagicWin7ine I had the AZ jab and it took me out for like 12hrs 8 of which were sleep02:00
waitingformagicI'll give you - theres some epic shit in there02:01
LjLmostly there's a ton of engineered adenoviruses02:01
waitingformagicIt's like a robust night on the drinks followed by meeting someone coming the other way who gives you a happy dead arm02:01
LjL(adenovirions?)02:01
waitingformagicand a kebab02:01
Win7ineI never have headaches, but I was up in bed at night aching the size of my small brain reaching down my spine ... apart from muscles all over ... not much temp tho.02:03
waitingformagicOK have you ever done a bottle of scotch in a one-er ?02:03
LjLWin7ine, did you take a paracetamol? it's often suggested, there's no evidence it interacts badly with the vaccine02:03
waitingformagicor been on what we call a Leo-Sayer ?02:03
waitingformagicwhich is an "ALL DAYER" drinking session ?02:04
LjL(of course i'm not a doctor and if you don't typically take paracetamol you shouldn't just take my word that it's okay to take it)02:04
waitingformagicin London02:04
LjLthat sounds like a recipe for a dead liver, waitingformagic02:04
LjLnot what i call a good idea02:04
waitingformagicjesus wept lads - most of the worst best things start out as bad ideas02:05
waitingformagic...stony ground02:05
* LjL rolls his eyes02:05
waitingformagicanyroad02:05
Win7ineOfficially it states: replication-deficient chimpanzee adenovirus vector encoding COVID spike glycoprotein. Produced in gentically modified HUMAN embryonic kidney cells.02:05
waitingformagicAZ or whatever vaccine is less than a hangover02:06
waitingformagicWin7ine02:06
waitingformagic...02:06
LjLside effects are not the same for everyone02:06
LjLi said it before, what's hard to understand about this?02:06
waitingformagicoh right02:06
Win7ineLjL yes, 1gramm of paracetamol on the 3 day to be bale to get to my office ...02:07
waitingformagicnot hard02:07
de-factothough those adenovirus vectors are replication deficient in normal human cells, they stole something from it that enabled it to replicate and implanted it into special cell cultures that are only used to grow those adenovirus vectors (with the implanted s-protein recipe) in 2000 liter bottles in factories02:07
waitingformagicpmsl Win7ine is a Dr02:07
waitingformagic:D02:07
waitingformagicomg I love the internet02:07
LjLde-facto, so it's the same virus, but in regular human cell it's unable to replicate, while it can replicate in whatever cell cultures they're using?02:08
Win7ineThis is a Chimp adeno02:08
LjLi actually never looked into the details of this02:08
de-factoyep LjL02:08
Win7ineQUestion is wher do they get and how many of the Human ebryonic kidney cells for this purpose?02:09
LjLWin7ine, the reason for that is mainly that, presumably, humans mostly haven't been exposed to it, so we don't have prior immunity, so we won't attack the vector instead of the S-protein... but i think with the unmodified virus, it would probably still replicate02:09
LjLisn't it a decades-old cell lineage?02:10
Win7ineLjL makes only helf sense as the Johnson-Johnson uses human known HNx flu virus vector02:11
LjLWin7ine, well, yes, but each adenovirus vaccine maker has chosen different strategies to deal with this potential issue02:11
Win7ineLjL Johnson appertly only one shot ...02:12
LjLWin7ine, for example Sputnik V uses human adenoviruses, but two different ones (one per shot), so 1) hopefully the second shot will be more effective as you haven't gained immunity to the adenovirus from the first, and 2) if you happen to already have immunity to one of them, at least it's unlikely you'll *also* have it to the other one02:12
waitingformagicSputnik V is therefore superior02:13
LjLWin7ine, yeah, as far as i can guess, J&J's strategy has been, keep it simple, make a trial with just one shot, and make that the "sales pitch": easier logistically, and more attractive to people who want to go on holidays this summer instead of having to deal with a second shot02:13
de-factonope Johnson and Johnson (Janssen) uses Adenovirus.26 (a human Adenovirus) as vector02:13
LjLwaitingformagic, i would not jump to that conclusion immediately02:13
LjLoh yes it's definitely an adenovirus too02:13
BrainstormNew from COVID19 Vaccine Tracker: Shannon McKearnan: Altimmune Inc: AdCOVID → https://is.gd/bnKPpU02:14
de-factoSputnik Adenovirus.26 for primer and Adenovirus.5 for booster (both human Adenoviruses)02:14
Win7ineAll vector is inferior as the human immune systems need one extra step to learn02:14
LjLone extra step to produce the protein02:15
de-factoall of them as replication-deficient vectors injecting the spike-glycoprotein DNA plasmid into humans cells02:15
Win7inemRNA is the way forward, also cen easily be reprogrammed for derivates02:15
waitingformagicdelivery ?02:16
waitingformagicproduction and delivery ?02:16
de-factothe translation of DNA into mRNA is not relevant for the immune system it happens inside the cells02:16
waitingformagicsorry went a bit early there02:16
waitingformagicwe've got to get this stuff to the whole bloody world for no money02:16
Win7ineLjL that extra step can lead to error and is consuming02:17
waitingformagicIt's not going to be the nice one02:17
LjLde-facto, but it does mean that any obstacle in that process will hinder efficacy. so if the immune system attacks the adenovirus, that's an obstacle02:17
waitingformagicits going to be the AK4702:17
de-factothe stimulation of the immune system may also happen because of the viral vector itself, but the desired provocation happens by exposing the s-protein on the cells surface02:17
waitingformagicstamped metal and just fucking works one02:17
waitingformagicsorry02:17
Win7inewaitingformagic Who is WE?02:17
waitingformagicHumanity02:17
waitingformagicyou're a member fuckstick02:18
LjLwaitingformagic, what are you on about?02:18
LjLdo not call people names please02:18
LjLyou're getting a bit annoying in all honesty02:18
waitingformagicapologies02:18
waitingformagicbanning people for being annoying ?02:19
LjLuh02:19
* Win7ine slaps waitingformagic around a bit with a large trout02:19
LjLi did not ban you02:19
LjLi see you're kind of anticipating my moves02:19
LjLif your intention is to end up being banned, i'm sure we can arrange that02:19
de-factoLjL, yes of course if immunity against that particular Adenovirus exists prior to it being injected as vector the immune system will just prevent it from infecting enough cells to produce enough s-protein to reach the desired effect, that pre-existing immunity can either be due to already a first dose with the same Adenovirus (AZ) or possibly due to it being a human Adenovirus that was already wide spread before (e.g. like Ad.5 as02:19
de-factoSputnik booster)02:19
waitingformagicugh ypu didintn o oo large TROUT in my face02:19
LjLwhat02:19
waitingformagicI got hit with a large Trout02:20
waitingformagicWin702:20
LjLthat wasn't me, and also that's obviously not a ban02:20
waitingformagicno it was not a ban02:20
waitingformagicenough of ME02:20
waitingformagiconward02:20
LjLright, onward. don't we all love being bossed around by the random newcomer who's mostly being disruptive.02:21
Win7ineIf I am not mistaken, Sputnik-V was ready just after the Chinese last year already?02:22
LjLWin7ine, i'm not sure what you mean by "ready"... they pulled a bit of a publicity stunt in being the "first" to be "ready", but really they weren't demonstrably any more ready than other vaccines, they didn't have an actual authorization yet02:22
de-factoquite an interesting read, here they describe how they developed it for MERS-CoV (basically they just modified it to work against SARS-CoV-2 later by switching the s-protein)02:22
de-factohttps://www.sciencedirect.com/science/article/pii/S0264410X1730656402:22
de-facto.title02:22
Brainstormde-facto: From www.sciencedirect.com: ChAdOx1 and MVA based vaccine candidates against MERS-CoV elicit neutralising antibodies and cellular immune responses in mice - ScienceDirect02:22
LjLthey were registered with Russia's medicine authority, that's all02:23
de-factonote: published 27 June 201702:23
Win7ineYes, had the ipression that they started jabbing the population earlier than the "WEst", obviously the chinese were first inocculating02:24
LjLWin7ine, but then the Chinese don't seem to be doing a tremendous job. they certainly kept the virus at bay better than the west, but their vaccines seem somewhat mediocre so far, and uptake isn't high, although they started early02:25
de-factothe Chinese gained a lot of speed with vaccinations now02:25
Win7ineWhere do you get this info from?02:25
LjLWin7ine, the Seychelles is the most vaccinated country in the world, with about 60% of the population vaccinated, mostly with SinoVac (60%) and the rest with AstraZeneca... unfortunately they're just having another big spike that made them lock down again02:25
LjLde-facto, oh yeah?02:26
de-facto366M doses https://ourworldindata.org/covid-vaccinations02:26
waitingformagicthe Chinese have a proven track record of social control02:26
LjLWin7ine, the news that a Chinese official actually admitted that their vaccines weren't all that effective made rounds of headlines. then they stated that he had been misinterpreted, but that doesn't surprise me. their vaccines are mostly inactivated virus, and they seem to have an efficacy of little more than 50%, at least iirc in the Brazil trial02:27
waitingformagicwestern world - civil rights ?! .... pooof gone in China02:27
LjLsometimes it's hard to remember where exactly i got the information, but i try to put the important things in the link that's in the topic02:27
de-factobasically meaning one dose per 4 Chinese people02:28
LjLde-facto, did they just add that "Our work belongs to everyone" box or did i just fail to notice it before?02:28
waitingformagicand all stats coming out of China have been known to be bullshit for ages02:28
waitingformagicRussia too02:28
LjLwaitingformagic, sure, in reality the virus is RAVAGING china even though we have footage of cities going on and about with their lives largely unaffected02:29
Win7ineLjL the big spike on the Seychelles is as big as it gets when reading the shoddy news ... I saw that too, only the info ended with the fact that even tho people are positive they are very mildly ill if at all. Same as everywhere else wher the vaccine flattens the re-infection outcome.02:29
LjLenough with this assumption that China isn't doing well but just doctoring the numbers, it's gotten old02:29
de-factoLjL, they advertised downloading the full dataset before too02:29
de-factoi think we even went through it on github02:29
waitingformagicChina is - the truth of the deal isn't02:30
LjLWin7ine, well, that's good, but i'd prefer a vaccine that's a bit more effective, also in preventing transmission. i think we agree since you said mRNA is "the way forward" after all02:30
LjLde-facto, i might just be blind sometimes02:30
de-factoits a huge dataset though, not loadable in to libre office or such02:30
de-factoneeds extraction first02:31
Win7ineNo vaccine will prevent transmission of a new varaiant that will trick02:31
waitingformagicso you chat her forever ?02:31
LjLWin7ine, a new variant is another pair of shoes, but i think the surge in the Seychells is not (known to be) due to a variant02:31
LjLwaitingformagic, what's YOUR point in asking a question such as that?02:31
waitingformagicforever-war02:31
Win7ineONly a new Vaccine quickly deployed agains the new varaiant will help, mRNA is capable of this02:31
LjLit's an IRC channel, yes, of course we chat here02:31
waitingformagicthe question whilst odd is this02:32
waitingformagicat what point will you all stop talking about THIS02:32
Win7ineLjL of course it is a new variant on the Seyshelles02:32
waitingformagicI'd tether my government to that point02:32
de-factowhen it became irrelevant, unfortunately not the case yet02:32
LjLWin7ine, i am disappointed to hear that Pfizer thinks they don't need a new booster for the variants. it's true that a study came out with their vaccine seemingly retaining 75% efficacy against B.1.351 (SA variant), but... i think they should be proactive here. are they only going to develop a "variant vaccine" once the variants are just uncontrollable with the original vaccine? Moderna is creating a booster on the other hand02:33
LjLwaitingformagic, "this" being COVID?02:33
LjLthis channel is about COVID, we won't stop talking about COVID02:33
waitingformagicwhen it becomes irrelevant02:33
LjLwhich will never happen02:33
waitingformagicha02:34
waitingformagicforever war02:34
LjLwe'll have to coexist with COVID. hopefully it won't be as bad as this, but it's not going away02:34
LjLmost scientists agree it's going to be endemic for a long long time02:34
waitingformagicjesus wept02:34
Win7ineLjL Pfizer produce, they want to sell what tyhey can do now in mass production, they are not interested in spending money to alter theri production line hence the blabla, BionTech are the innovators and they will output directly02:34
LjLsometimes pandora's jar can't just be closed back again, y'know02:35
waitingformagicgood luck02:35
yutaIs there ivermectin fan?02:35
LjLwell that's a relief02:35
de-factomy hope would be that humanity does not waste all of the opportunities and time windows available to get rid of the COVID pandemic, hence maybe it will be irrelevant at some point in the future, yet so far it always tends to go worse than my expectations and i am not exactly an optimist with this02:35
BrainstormUpdates for France: +16861 cases (now 5.9 million) since 21 hours ago — Netherlands: +4271 cases (now 1.6 million), +9 deaths (now 17551) since 21 hours ago — United Kingdom: +1763 cases (now 4.5 million), +11 deaths (now 127790) since 21 hours ago — Germany: +6512 cases (now 3.6 million) since 21 hours ago02:36
LjLWin7ine, yes, they want to make money, i wonder if BioNTech will be able to push them to... still make money, but with the best possible vaccine02:36
LjLor if they can be nudged by governments, or someone02:36
LjLi just don't think continuing with the current production without modification is going to be good in the long run02:36
LjLexcept for Pfizer's stocks, maybe02:36
de-factotbh i think its also about marketing, just imagine, Apple announcing the new Iphone and its cool new features half a year before it comes to market, how would that impact their sales of current Iphones?02:37
de-factodoesnt that even have a name? i dont remember it02:38
Win7ineLjL BionTech are also setting up manufacturing in Singapore02:38
de-factothat effect i mean02:38
de-facto"Osborne effect"02:40
de-factohttps://en.wikipedia.org/wiki/Osborne_effect02:40
Win7ineAlso their native Marburg site has been expanded to be able to output 750Million doses per year02:40
LjLde-facto, i never remember these names. yeah... i guess... i don't know, it depends on how the contracts are written also02:45
de-factoyeah indeed02:45
de-factoafaik EU bought 900M doses from them but probably against future variants02:45
Win7ineSo with these developments around the true innovators (BionTech)  Pfizer is merely holding on to what they are making right now and pushing more of it wether still efficient or not ...02:49
LjLde-facto, i *really hope* the put a clause about variants in that gigantic 900+900m doses contract02:50
LjLmaybe at some point we'll know from whoever likes to leak things :P02:50
Win7ineSame goes for all the others ... It is all about the profit. Not humans.02:50
de-factoLjL,  i do think so as it was the whole purpose of that contract to allocate doses for future VoCs in advance02:51
LjLi don't know de-facto, i'll believe it when i see the contract, i've witnessed more than enough politicians making stupid choices and bad contracts already to blindly believe in them now02:53
de-factoPfizer rised the costs from 12€ to 19.50€ per dose though02:53
LjLoh well02:54
LjLthat's still less than €15002:55
de-factoat least its good to make the impression of that in advance02:55
LjLde-facto, have you noticed the part of Johnson's announcement where they're changing the second dose schedule from 12 weeks to 8 weeks?02:58
LjLthat's sort of interesting02:58
LjLin theory, for AZ, 12 weeks was supposed to be "optimal"02:58
de-factoso thats 17.5B€ contract, peanuts?02:58
LjLbut then i think they were using 12 weeks also for Pfizer02:58
[Krakenjohnsons has a 2nd dose?02:59
de-factohuh? Janssen always was 1 dose afaik and AZ 2 dose, UK saying they want to sooner reach fully vaccinated for more people because of better protection against variants02:59
LjL[Kraken, no?02:59
LjLdid i say Johnson instead of Pfizer or something?03:00
[Kraken:)03:00
* de-facto opens his third beer :D03:00
Win7ineLjL Johnson is a ONE JAB vaccine, there is not second03:00
BrainstormUpdates for Fr. Polynesia: +18 cases (now 18815) since 3 days ago03:01
de-factooh lol Boris Johnson03:01
LjLWin7ine, i know...03:01
LjLi'm not the one saying it isn't03:01
de-factoyes LOL im am drunk LOL03:01
LjLoooooh03:02
LjLyes Boris Johnson03:02
de-factoBoris Johnson, Johnson and Johnson with Janssen and all those "J"s got me confused03:02
LjL:D03:02
Win7ineBoris, 12->8 weeks, yes ecause of the new India variant03:02
LjLlet's have a laugh03:02
de-facto:P03:02
Win7ineHaha03:02
Win7ineha03:03
LjLWin7ine, supposedly so, but it's an... interesting choice. i guess (although he didn't say it) that it will mean people under 40, who are not yet eligible, will take longer to be vaccinated. it would also mean that they *don't* expect just one dose to be effective against the Indian variant...?03:03
Win7ineNo single does is as effective as a double03:04
de-factoyes but Boris the J said it was due to reaching fully vaccination status earlier for those potentially vulnerable hence the elderly with only one dose, to give them better protection against VoCs03:04
Win7inefor any variant03:04
LjLWin7ine, sure, but "for any variant" is the key here... if they thought 12 weeks was fine *before* this variant, then what changed?03:04
LjLde-facto, but those are people who already had one dose and so, were unlikely to get severely sick anyway (from what we know). but the younger people are not protected at all yet03:05
de-factous talking about alcohol is unhealthy got me realizing i did not drink it since... new years, hence i bought beer today :D03:05
Win7ine12 weeks wa not fine, it was omnly because of limited supply, in fact 4 weeks is ideal03:05
LjLi'm not saying it's a wrong decision, just that it's an interesting small change of course03:05
de-factoLjL, yeah i am just repeating what he said in the speech you linked above03:06
LjLWin7ine, well, 4 weeks is more or less ideal with Pfizer, but AZ actually contended that the 12 week schedule is probably better (it's hard to tell from their largely botched trial, but it's possible)03:06
Win7ineAll trials used 4 weeks booster, only when supply issues and larger numbers started to play a role did they tweak what is good.03:06
LjLWin7ine, also you might enjoy this italian "study" that was posted here before you joined (i scarequote it because we have the article, but didn't find the actual study yet) https://www.italy24news.com/covid-19/52534.html03:07
LjLWin7ine, no, with AZ there was an additional complication03:07
Win7ineSuch as?03:07
LjLWin7ine, initially the Oxford trial gave people half the amount of vaccine than they later settled on. they realized that there didn't seem to be enough reactogenicity with that small dose, so they double it in the next participants. but at the same time, they weren't sure what to do with the participants who had gotten the half dose, so their second dose was delayed. later, surprisingly, it turned out that the half-dose arm actually seemed to have 90%03:09
LjLprotection, as opposed to 60% or so for the other arm. initially they said it was probably because of the smaller dose (bit of a paradox effect, but maybe due to the immune system's reaction to excess adenovirus), but later they said it was probably because those same people had waited longer to get their second dose (also theoretically plausible: if you wait until the antibodies *to the adenovirus* are less present, the booster might work better)03:09
LjLde-facto can confirm if i remember the story right, i think03:10
Win7ineLjL that contradicts intial sudies where Astra is less effective ... All greed.03:10
LjLWin7ine, i'm not saying i completely buy into this interpretation, i'm just saying it's what AZ eventually claimed as their interpretation of the study results03:11
LjLin fact if we're talking *personally*, i'm qute fed up with AZ's shenanigans, and at this point i'm happy the EU is just going with Pfizer03:11
Win7ineTime will tell03:11
LjL... i mean BNT :P03:12
de-factoi thought it was like they indended full dose -> full dose but messed up the production for one part of the trial (was it UK?) and ended up with half-dose -> full-dose then later realizing that it was more efficacious in that arm03:12
[Krakendoes brainstorm go idle, when folks chat in here?03:12
Win7ineFAct is that the BionTech/Pfizer shot is triple the price of the Oxford/AstraZ03:12
* de-facto pets Brainstorm03:13
* Brainstorm starts to coruscate de-facto with some pacific instrumentality 03:13
Win7ineand is not easily handled becaiuse of refrigeration need03:13
de-factoonly on the long term03:13
* Birrosso stabs Brainstorm.03:14
de-factodo it without the dot03:14
BirrossoW-Why is it ignoring me? Is it the dot?03:14
* Birrosso stabs Brainstorm03:14
* Brainstorm starts to reject Birrosso with some moneyless spite 03:14
BirrossoSeriously?03:14
* Birrosso sighs.03:14
de-factoBNT can be handled at fridge temps, was it for 5 days or such after it was taken out of deep freezer?03:15
de-factoand afaik CureVac will be able to last like 3 months at normal fridge temps, hence its possible to do such things with mRNA03:15
LjL[Kraken, no, Brainstorm just keeps doing its thng03:15
LjLyou just notice it more when folks aren't talking i suspect :P03:15
LjLWin7ine, CureVac is promising to be usable at fridge temperatures. Pfizer already went from -80°C to finding out that -20°C is acceptable. so this aspect might get better with mRNA vaccines over time.03:16
LjLAZ is cheaper, for sure03:17
LjLi know this reeks a bit of "third-world-tier-vaccines", but i think given the horrific situation in India right now, we (as in the EU) should just give our AZ doses to India, and use Pfizer which we have better means to handle (India may have trouble keeping -80°C in some remote village!)03:17
LjLand Pfizer/BNT is coming in reasonably large amounts for us now03:18
de-factointeresting, people under the age of 40 will get mRNA in UK too they just said03:18
Win7ineLjL exaclty, India manufactures the bulk of Az, cheaply, let the have it for their own03:18
de-facto(i am still trying to finish watching the Boris announcement you linked earlier)03:19
[Krakende-facto: that must be painful03:20
de-factolol yeah i am trying hard03:20
LjLWin7ine, well, they're definitely keeping the portion they manufacture themselves at this time03:21
LjLbut i say let's give them our stock too03:22
LjLbased on a recent report, it looks like in Gujarat they may have 15x as many deaths as officially reported03:22
de-factoisnt that what USA is trying to do?03:22
LjLwhich does not surprise me because the official numbers are small (relative to the population), but people who live there tell a different story03:22
LjLde-facto, i don't know03:22
LjLthey've barely been convinced to take their hands off those unused AZ doses! i don't know who they're going to give them to03:23
LjLi'd heard mainly Mexico and Canada03:23
LjLbut i'm not really sure03:23
de-factohmm yeah that also could make sense03:23
LjLde-facto, the announcement that <40 people will get mRNA is older, though03:23
LjLi hope that won't make it longer for them to get their vaccine03:24
de-factoafaik EU also begins to give doses to the eastern countries such as Ukraine etc03:24
LjLi have a friend there who's under 40 and he doesn't work remotely (as in, he works in presence) so i hope he can get vaccinated soon, especially now with this variant03:24
de-factoi think i read a headline about Lithuania contributing doses to them from brainstorm a few days ago03:24
Win7ineSadly if one watches social/religious events @ganges river etc it is obvious that the rage is hard03:24
LjLWin7ine, but also political rallies. Modi is a <censored>03:24
BirrossoNo one here is discouraging using AZ, just warning that you could die of deep vein thrombosis... or something like that.03:24
LjLWin7ine, but at the same time, the spike in India pre-dates those religious events. they'll certainly not make things better, but i don't think they are "the" origin of the spike03:25
LjLBirrosso, lol, i like the way you put it03:25
BirrossoThe details are a bit hazy.03:25
Win7ineBirrosso DVT by AZ is documented deeply but can occur with others just the same03:28
BrainstormUpdates for Panama: +588 cases (now 370043), +4 deaths (now 6292) since a day ago03:38
BrainstormUpdates for Saint Lucia: +63 cases (now 4788) since a day ago04:03
BrainstormUpdates for Egypt: +1197 cases (now 243317), +56 deaths (now 14206) since a day ago — Germany: +8553 cases (now 3.6 million) since 22 hours ago — France: +13753 cases (now 5.9 million) since 21 hours ago — Netherlands: +4139 cases (now 1.6 million), +8 deaths (now 17554) since 21 hours ago04:40
de-factolong covid ~ 10% of cases according to Lothar Wieler from RKI04:54
BrainstormUpdates for Sao Tome and Principe: +4 cases (now 2324) since 3 days ago05:30
BrainstormNew from r/WorldNews: worldnews: Taiwan raises COVID-19 alert level, reports 180 new cases → https://is.gd/NUyCNB05:46
BrainstormNew from EurekAlert!: (news): Rutgers reports first instance of COVID-19 triggering recurrent blood clots in arms → https://is.gd/GcgNpn06:29
CoronaBot/r/coronavirus: Kroger Reveals That It Paid CEO $22.4 Million Shortly After He Cut Workers’ COVID-19 Hazard Pay (10324 votes) | https://labor411.org/411-blog/kroger-reveals-that-it-paid-ceo-22-4-million-shortly-after-he-cut-workers-hazard-pay/ | https://redd.it/ncjvac06:43
BrainstormUpdates for Belgium: +1631 cases (now 1.0 million), +19 deaths (now 24664) since a day ago07:09
BrainstormUpdates for Rio Grande do Norte, Brazil: +11768 cases (now 1.3 million), +122 deaths (now 32335) since a day ago — Parana, Brazil: +9338 cases (now 1.0 million), +145 deaths (now 24330) since a day ago — Alabama, United States: +4918 cases (now 537813), +23 deaths (now 11024) since a day ago — Moscow, Russia: +3818 cases (now 1.1 million), +60 deaths (now 19128) since a day ago07:34
BrainstormUpdates for India: +326098 cases (now 24.4 million), +3923 deaths (now 264918) since 23 hours ago08:36
BrainstormNew from r/Coronavirus: Daily Discussion Thread | May 15, 2021: Please refer to our Wiki for more information on COVID-19 and our sub. You can find answers to frequently asked questions in our FAQ , where there is valuable information such as our: → https://is.gd/AQYOQD09:09
liptoner[m]Any reason someone under 60 should get the jab if they are not vulnerable?10:01
BrainstormNew from The Indian Express: World: China cancels Mt Everest climbs over fears of Covid-19 from Nepal → https://is.gd/vevFd110:02
BrainstormUpdates for Taiwan: +185 cases (now 1475) since a day ago10:03
BrainstormNew from BBC Health: Covid: Get the jab plea as Army deployed in hotspots: Eligible people in areas where the Indian virus variant is circulating are urged to get vaccinated. → https://is.gd/gxlM5310:13
finely[m]<Win7ine "@LjL how do you think any of the"> If it was made available patent free all the biotech manufacturing capability that is being utilised could be making vaccines. There is a single company in Bangladesh that could be making 600 000+ doses a year right now. It isn't because of patent law. There are other companies wanting to make vaccines that can't yet. Let's say that's a conservative estimate if 1 billion doses10:32
finely[m]of vaccine a year that we are not making, but could.10:32
BrainstormUpdates for Tamil Nadu, India: +31892 cases (now 1.5 million), +288 deaths (now 17056) since a day ago — West Bengal, India: +20846 cases (now 1.1 million), +136 deaths (now 12993) since a day ago — Odisha, India: +12390 cases (now 588687), +22 deaths (now 2273) since a day ago — Manipur, India: +726 cases (now 38322), +16 deaths (now 552) since a day ago10:40
BrainstormNew from Reddit (test): CoronavirusUK: Novavax offers 89.7% protection against B.1.1.7 strain; with 100% protection against severe cases → https://is.gd/MYoSGL10:55
finely[m]<liptoner[m] "Any reason someone under 60 shou"> Everyone is vulnerable. We don't have a way to predict which young, healthy person will die of COVID and which person will be fine. And long COVID is no joke. Potentially life altering disability for the rest of your life. And you may be OK, but you pass the infection onto someone you love and kill them (possibly without ever getting symptoms yourself).10:58
finely[m]If its the Astra Zenaca one though, there us a small chance of getting potentially fatal blood clots. Even then, for most people (especially older people) the risk of dying from COVID is higher. The other vaccines are safe from serious side effects.11:05
BrainstormUpdates for Bolivia: +2509 cases (now 329733), +42 deaths (now 13451) since 14 hours ago11:05
BrainstormNew from Medical Xpress: Did the coronavirus escape from a lab? The idea deserves a second look, scientists say: Eighteen scientists from some of the world's most prestigious research institutions are urging their colleagues to dig deeper into the origins of the coronavirus responsible for the global pandemic. → https://is.gd/xRvoA711:17
BrainstormNew from Politico: Borders: UK to stop detaining people without work visas in removal centers during pandemic → https://is.gd/Z2QYSy11:38
CoronaBot/r/covid19: Prospective Case-Control Study of Cardiovascular Abnormalities 6 Months Following Mild COVID-19 in Healthcare Workers (80 votes) | https://www.sciencedirect.com/science/article/pii/S1936878X21003569 | https://redd.it/ncdq8q11:38
BrainstormNew from The Indian Express: World: UK eager for a big reopening thanks to vaccine success → https://is.gd/BLgrTj11:49
BrainstormNew from Gazzetta Ufficiale italiana: MINISTERO DELLA SALUTE - ORDINANZA 14 maggio 2021: Ulteriori misure  urgenti  in  materia  di  contenimento  e  gestionedell'emergenza epidemiologica da COVID-19 nelle  Regioni  Sardegna  eSicilia. (21A03052) → https://is.gd/vnF51712:10
BrainstormNew from r/WorldNews: worldnews: Mysterious New ‘News’ Sites Can’t Stop Praising Modi Amid COVID Crisis → https://is.gd/8RAA1213:15
CoronaBot/r/covid19: Efficacy of the NVX-CoV2373 Covid-19 Vaccine Against the B.1.1.7 Variant (81 votes) | https://www.medrxiv.org/content/10.1101/2021.05.13.21256639v1 | https://redd.it/ncs69p14:09
BrainstormUpdates for Bangladesh: +261 cases (now 779796), +22 deaths (now 12124) since a day ago14:36
ketasmy age group can get shot now15:05
de-factowhat age is that?15:06
ketas3715:06
de-facto%ifr 3715:06
Brainstormde-facto, for every 2144 infections at that age, one would progress to a fatal outcome, on average.15:06
ketas%ifr 12015:06
Brainstormketas, for every 0 infections at that age, one would progress to a fatal outcome, on average.15:06
ketas%ifr 10015:07
Brainstormketas, for every 1 infections at that age, one would progress to a fatal outcome, on average.15:07
de-factomostly accurate for ranges where the majority of such data exists, hence probably like 50-90 or such15:08
de-factomy dad for example15:08
de-facto%ifr 7215:08
Brainstormde-facto, for every 31 infections at that age, one would progress to a fatal outcome, on average.15:08
ketas%ifr 7615:08
Brainstormketas, for every 19 infections at that age, one would progress to a fatal outcome, on average.15:08
ketasmy mother15:09
ketaswho has received first dose of biontech now15:09
de-factoyeah at that age the benefit from vaccination is enormous15:09
de-factomy parents too, 1st dose of BNT, i am very happy about that15:09
de-factome, i dont have any yet15:09
de-facto%ifr 3915:10
Brainstormde-facto, for every 1684 infections at that age, one would progress to a fatal outcome, on average.15:10
ketas%ifr 1315:10
Brainstormketas, for every 38797 infections at that age, one would progress to a fatal outcome, on average.15:10
ketas%ifr 115:10
Brainstormketas, for every 165044 infections at that age, one would progress to a fatal outcome, on average.15:10
ketas%ifr 015:10
Brainstormketas, for every 186209 infections at that age, one would progress to a fatal outcome, on average.15:10
de-factoyeah but for such young it also becomes less accurate, not enough data for that age15:10
ketashmm15:10
ketas%ifr -115:11
Brainstormketas, for every 210088 infections at that age, one would progress to a fatal outcome, on average.15:11
ketas:P15:11
de-factohaha :D15:11
ketashow come15:11
ketas%ifr -99999999915:11
BrainstormZeroDivisionError: float division by zero (file "/home/brainstorm/brainstorm/bot/modules/covid.py", line 484, in ifr)15:11
ketasops15:11
ketaswhere did the /0 come from15:12
ketas:)15:12
de-factoits an exponential interpolating the data that mostly was collected where the majority of fatal outcomes happened, hence in the elderly: 186209÷(2^(age÷5,75)) doubling with each increase of age by 5.75 years15:14
ketassadly many people have divided by zero due covid15:14
de-factoyeah its probabilities of course one never knows before15:15
de-factointerpolation comes from metastudy (summarizing other studies about IFR)15:18
de-facto.title https://www.springermedizin.de/covid-19/assessing-the-age-specificity-of-infection-fatality-rates-for-co/18667556?fulltextView=true15:18
Brainstormde-facto: From www.springermedizin.de: Springer Medizin – Mein Arztwissen | springermedizin.de15:18
de-factoactually it seems they use data from 5 to 95 years15:20
BrainstormNew from r/WorldNews: worldnews: Pfizer makes billions from COVID-19 vaccines, payed for with tax money. But the company has a different attitude when it comes to their own taxes: Pfizer tries to avoid taxes worldwide, through the Netherlands. → https://is.gd/Jr6rFj15:34
BrainstormNew from This Week In Virology: TWiV 755: COVID-19 clinical update #62 with Dr. Daniel Griffin: In COVID-19 clinical update #62, Daniel Griffin covers outdoor transmission of the virus, safe use of NSAIDS, expansion of Pfizer/BioNTech vaccine to include 12-15 year olds, post-disease Mucormycosis, and hydroxychloroquine treatment associated with [... want %more?] → https://is.gd/a12UML15:56
chile09[m]Where are the GoF articles?15:57
de-factoGoF?15:59
dTalGame of Frones15:59
de-factoGain of Function?15:59
de-factoSARS-CoV-2 gains its function itself, the variants become more infectious and gain some evasive capabilities in partly immune populations, all as result of the natural selection for randomly occurring mutations16:01
BrainstormUpdates for Nepal: +8046 cases (now 447704), +187 deaths (now 4856) since 23 hours ago16:04
de-facto.title https://en.wikipedia.org/wiki/Variant_of_concern16:04
Brainstormde-facto: From en.wikipedia.org: Variant of concern - Wikipedia16:04
CoronaBot/r/covid19: Serbia begins paying citizens to receive Covid19 vaccine. (81 votes) | https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(21)01097-7/fulltext?utm_campaign=WR&utm_content=166756176&utm_medium=social&utm_source=twitter&hss_channel=tw-27013292 | https://redd.it/nctpab16:34
BrainstormUpdates for Germany: +89 deaths (now 85999) since 23 hours ago16:41
BrainstormUpdates for Canada: +35 deaths (now 24863) since 23 hours ago17:30
BrainstormNew from Reddit (test): Saturday 15 May 2021 Update: submitted by /u/HippolasCage to r/CoronavirusUK → https://is.gd/HTIF5N17:33
finely[m]They are going all out now.   Trying lots of lies hoping one of them will stick.17:48
finely[m]https://theintercept.com/2021/05/14/covid-vaccine-waiver-generic-phrma-lobby/17:48
rpifanim not surprised17:50
BrainstormUpdates for Italy: +6652 cases (now 4.2 million), +136 deaths (now 124063) since 22 hours ago18:33
BrainstormNew from r/WorldNews: worldnews: Mysterious New ‘News’ Sites Can’t Stop Praising Modi Amid COVID Crisis. Modi officials are sharing articles from a site that tweets in all caps, and has a name that is eerily similar to the UK newspaper. → https://is.gd/Rk4JbF18:47
BrainstormNew from The Indian Express: World: US warns extremists may strike as COVID-19 restrictions ease → https://is.gd/hpX36X19:09
BrainstormUpdates for Sri Lanka: +3616 cases (now 140471) since 23 hours ago — Cuba: +1383 cases (now 123221), +11 deaths (now 796) since 22 hours ago19:35
BrainstormUpdates for Vietnam: +131 cases (now 3985) since 10 hours ago20:37
BrainstormUpdates for France: +74 deaths (now 107503) since 19 hours ago21:39
BrainstormUpdates for N. Mariana Is.: +2 cases (now 172) since 5 days ago22:04
BrainstormNew from Reddit (test): Covid2019: Pfizer and Moderna jabs may help guard against next coronavirus pandemic → https://is.gd/jWJnNQ22:41

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