libera/##covid-19/ Monday, 2021-05-17

BrainstormUpdates for Germany: +48 deaths (now 86109) since 23 hours ago00:29
BrainstormNew from BBC Health: (news): Covid-19: Lockdowns ease for millions in England, Wales and most of Scotland → https://is.gd/RWHLAO01:06
BrainstormNew from Bloom Lab: @DanLikeProteins: RT by @jbloom_lab: Excited to share a preprint for stabilization of the SARS-CoV-2 receptor-binding domain (RBD) to assist translatability of RBD-based vaccines. Stabilized RBDs = higher yield, more thermostable, more resistant to aggregation, equally immunogenic.https://www.biorxiv.org/content/10.1101/2021.05.15.444222v11/7https://is.gd/ZqrMKD01:28
BrainstormNew from BBC Health: 'My exhausting smear test battle': Transgender men, such as Laurie, are not automatically contacted for potentially life-saving smear tests. → https://is.gd/t5gshW01:38
BrainstormNew from Bloom Lab: @jbloom_lab: Super interesting study about the 1918 flu pandemic that sequences viruses from archived formalin-fixed samples from first (milder) wave. Some indication virus may have adaptively evolved from first to second (more deadly) wave, i.e. mutations to NP that increased MxA resistance. → https://is.gd/7TnfGG01:49
BrainstormUpdates for France: +11330 cases (now 5.9 million), +69 deaths (now 107572) since 23 hours ago — Netherlands: +5563 cases (now 1.6 million), +16 deaths (now 17576) since 23 hours ago — China: +20 cases (now 96780) since 23 hours ago — United Kingdom: +1511 cases (now 4.5 million), +4 deaths (now 127807) since 23 hours ago02:33
BrainstormNew from Reddit (test): China_Flu: The C.D.C. director offers a stark reassurance: Only unvaccinated people are at risk by unmasking. → https://is.gd/hdyAPy02:42
BrainstormNew from Virological.org: Latest posts: Early appearance of two distinct genomic lineages of SARS-CoV-2 in different Wuhan wildlife markets suggests SARS-CoV-2 has a natural origin: Response on the Origin of SARS-CoV-2 Those who know of the longtime proximity and collaboration between Bob Garry and myself will not find it surprising that I concur with [... want %more?] → https://is.gd/hCysVy02:53
BrainstormNew from Politico: For the next pandemic, we need plans not heroes: The coronavirus crisis demanded creativity, quick thinking and sacrifice. Next time, let's just make sure thing are ready beforehand. → https://is.gd/268nLP04:08
BrainstormUpdates for France: +6974 cases (now 5.9 million), +40 deaths (now 107592) since 21 hours ago — Netherlands: +4443 cases (now 1.6 million), +13 deaths (now 17579) since 21 hours ago — United Kingdom: +970 cases (now 4.5 million), +2 deaths (now 127808) since 21 hours ago04:38
LjL%cases france04:38
BrainstormLjL: In France, there have been 5.9 million confirmed cases (8.8% of the population) and 107592 deaths (1.8% of cases) as of 23 seconds ago. 81.2 million tests were performed (7.3% positive). See https://offloop.net/covid19/?default=France for time series data.04:38
LjL%cases italy04:38
BrainstormLjL: In Italy, there have been 4.2 million confirmed cases (6.9% of the population) and 124156 deaths (3.0% of cases) as of 10 hours ago. 62.9 million tests were performed (6.6% positive). Fatality can be broadly expected to lie between 3.1% (assuming prevalence as in tests) and less than 3.2% (considering only deaths and recoveries). See https://offloop.net/covid19/?default=Italy for time series data.04:38
LjLwe still have so many more deaths than comparable countries :\04:38
LjL%cases spain04:39
BrainstormLjL: In Spain, there have been 3.6 million confirmed cases (7.7% of the population) and 79339 deaths (2.2% of cases) as of 2 days ago. 48.1 million tests were performed (7.5% positive). See https://offloop.net/covid19/?default=Spain for time series data.04:39
* bluesclues waves to MetaNova 05:02
BrainstormNew from Politico: Boris Johnson banks on British caution as restrictions lift: The UK prime minister presses ahead with lifting the next round of COVID restrictions from Monday. → https://is.gd/ZqxsY405:12
BrainstormUpdates for Belgium: +1852 cases (now 1.0 million), +23 deaths (now 24709) since 23 hours ago05:40
BrainstormNew from The Indian Express (Health): Fitness: ‘Won’t let the pandemic get the best of me’: Sameera Reddy shares motivational post on fitness → https://is.gd/7DwnKw05:44
CoronaBot/r/covid19: Durability of mRNA-1273-induced antibodies against SARS-CoV-2 variants (80 votes) | https://www.biorxiv.org/content/10.1101/2021.05.13.444010v1 | https://redd.it/ne0wx805:54
BrainstormNew from The Indian Express: World: Covid is airborne, scientists say; Now authorities think so, too → https://is.gd/fp87BR06:16
BrainstormNew from The Indian Express: World: Brazil city offers Covid shots to all 18-60 as part of test → https://is.gd/iXSHQa07:20
BrainstormUpdates for Saint Petersburg, Russia: +767 cases (now 427382), +36 deaths (now 13762) since 23 hours ago — Moscow Oblast, Russia: +672 cases (now 260103), +12 deaths (now 5997) since 23 hours ago — France: +10461 cases (now 5.9 million), +60 deaths (now 107612) since 23 hours ago — Kaliningrad, Russia: +67 cases (now 32704) since 23 hours ago07:32
BrainstormNew from StatNews: Sanofi, GSK announce positive early results for their Covid-19 vaccine candidate: Sanofi and GSK announced positive results from a Phase 2 clinical trial of their Covid-19 vaccine today. They plan to start a Phase 3 trial in the coming weeks. → https://is.gd/wg3OJT07:42
pwr22Oh it's Monday, we are allowed to meet people indoors in the UK!07:52
pwr22Feels weird07:53
BrainstormNew from The Indian Express: World: From India, Brazil and beyond: Pandemic refugees at the border → https://is.gd/QRA2Kk08:15
BlankspaceCan you have covid without cough08:28
darsieyes08:28
BlankspaceHow do you know08:28
darsiesome, especially children can have no symptoms.08:28
BlankspaceI have fever08:29
BrainstormUpdates for India: +281386 cases (now 25.0 million), +4091 deaths (now 273028) since 23 hours ago08:34
BrainstormNew from Politico: Business and competition: ‘Way too soon’ for second coronavirus recovery plan, Vestager says → https://is.gd/U73vop08:57
BrainstormNew from Science-Based Medicine: How antimaskers weaponize techniques of scientific analysis to attack mask mandates: There's a new paper out analyzing how antimask activists weaponize the tools of data visualization and scientific argumentation to produce convincing antimask propagands. Antimaskers are claiming that it shows that they are more [... want %more?] → https://is.gd/mT1uXx09:08
BrainstormUpdates for Taiwan: +335 cases (now 2017) since a day ago09:11
BrainstormUpdates for Thailand: +9635 cases (now 111082), +25 deaths (now 614) since a day ago09:36
BrainstormUpdates for Andhra Pradesh, India: +24171 cases (now 1.4 million), +101 deaths (now 9372) since a day ago — Sikkim, India: +340 cases (now 11410), +2 deaths (now 205) since a day ago10:38
BrainstormNew from The Indian Express: World: Free at last to hug and party: UK reopens for business → https://is.gd/CWNhjS10:44
BrainstormNew from StatNews: At Illumina, the ‘era of the genome’ has arrived. But what role will the company play?: Just as the pandemic gave drug makers a chance to show what they could do, it has also demonstrated the potential of large-scale study of genetics. → https://is.gd/Vzx2Rm10:55
BrainstormNew from Reddit (test): CoronaVirus_2019_nCoV: Even when the vaccine travels to them, many Mainers won't take it → https://is.gd/rKZbKN11:16
BrainstormNew from BMJ: Antivirals against SARS-CoV-2 by autumn?: The UK government has launched a covid-19 antivirals taskforce with the aim of deploying drugs for home treatment by autumn this year.1 The description suggests that the government wants direct... → https://is.gd/Wm9NLa11:48
BrainstormNew from Retraction Watch: ‘Preprints are works in progress’: The tale of a disappearing COVID-19 paper: When a Twitter user tipped us off last week to the mysterious disappearance of a preprint of a paper on a potential new therapy to treat Covid-19, we were curious. Was it a hidden retraction, or something else?  The article, titled [... want %more?] → https://is.gd/9jjGed12:09
CoronaBot/r/coronavirus: Unvaccinated People Are Most at Risk by Unmasking, C.D.C. Director Says (10019 votes) | https://www.nytimes.com/2021/05/16/world/cdc-director-unvaccinated-masks.html | https://redd.it/ndv45k12:27
BrainstormNew from PubMed: The Impact of COVID-19 on National Clinical Trials Network Breast Cancer Trials: PURPOSE OF REVIEW: The COVID-19 pandemic has had a devastating impact on virtually all aspects of the healthcare system, including oncology clinical trials. The purpose of this review is to describe the impact of the pandemic on national breast cancer [... want %more?] → https://is.gd/S8oqAQ13:14
BrainstormNew from r/WorldNews: worldnews: "I Drink Cow Urine Every Day, So Don't Have Covid": BJP MP Pragya Thakur==‘And you wonder why we have a brutal second wave here in India’ → https://is.gd/3ulTzj13:25
BrainstormUpdates for Macau: +1 cases (now 50) since 14 days ago13:32
BrainstormNew from EMA: What's new: Medicine: Human medicines European public assessment report (EPAR): COVID-19 Vaccine Moderna, COVID-19 mRNA Vaccine (nucleoside modified), COVID-19 virus infection, Date of authorisation: 06/01/2021, Revision: 3, Status: Authorised → https://is.gd/ApJcx913:47
guriyaMorning people14:23
BrainstormUpdates for Iceland: +125 cases (now 6662) since 2 days ago14:34
BrainstormNew from The Indian Express (Health): Health: COVID 19: Is plasma therapy effective? A doctor explains → https://is.gd/h9EjF714:52
BrainstormNew from StatNews: Pharma: STAT+: Pharmalittle: Sanofi and Glaxo tout positive Covid-19 vaccine results; Pfizer exec warns IP waiver will cause materials shortage → https://is.gd/8GfRkp15:26
BrainstormUpdates for Nepal: +9198 cases (now 464218), +214 deaths (now 5215) since 23 hours ago — Switzerland: +2650 cases (now 682160), +5 deaths (now 10736) since 23 hours ago — Bangladesh: +698 cases (now 780857), +32 deaths (now 12181) since a day ago15:37
BrainstormNew from EMA: News and press releases: More flexible storage conditions for BioNTech/Pfizer’s COVID-19 vaccine, CHMP, 17/05/2021: EMA’s human medicines committee (CHMP) has recommended a change to the approved storage conditions of Comirnaty, the COVID-19 vaccine developed by... → https://is.gd/4iFlpF15:37
BrainstormNew from FDA Press Releases: FDA In Brief: FDA Provides Guidance on Master Protocols for Evaluating Prevention, Treatment Options for COVID-19: The FDA issued a final guidance that describes the agency’s current recommendations to sponsors of master protocols evaluating drugs for the treatment or prevention of COVID-19. → https://is.gd/gGOMz616:32
-RSSBot[LjLmatrix- Feed: Telefonata del Presidente Draghi con il Primo Ministro della Repubblica Popolare Cinese, Li Keqiang ( https://www.governo.it/it/articolo/telefonata-del-presidente-draghi-con-il-primo-ministro-della-repubblica-popolare-cinese-li )17:03
BrainstormUpdates for Germany: +8540 cases (now 3.6 million) since 23 hours ago17:03
de-facto.title https://impfdashboard.de/17:03
Brainstormde-facto: From impfdashboard.de: COVID-19 Impfdashboard17:03
de-factoGermany: Vaccination rate up to 75% at least one dose: (84019461−30790970−(1−0.75)×84019461)÷((30790970−11101336)÷40) ~  65 days from now hence 2021-07-2117:04
de-factoGermany: Vaccination rate up to 75% at fully two dose: (84019461− 9332160−(1−0.75)×84019461)÷(( 9332160− 4688392)÷40) ~ 462 days from now hence 2022-08-2217:04
de-factoOf course when all the parameters stay as they are.17:04
de-factoMeaning immunity of now fully vaccinated already will be expired (over 6 months old) 2.5-fold when we reach 75% for all of population in Germany.17:04
de-factoConclusion: WAY too slow, 0.5M first dosers and 116k second dosers per day are just not enough by a long shot17:05
CoronaBot/r/covid19: Sanofi and GSK COVID-19 vaccine candidate demonstrates strong immune responses across all adult age groups in Phase 2 trial (82 votes) | https://www.sanofi.com/en/media-room/press-releases/2021/2021-05-17-07-30-00-2230312 | https://redd.it/nebeyb17:05
finely[m]https://www.abc.net.au/news/2021-05-17/queensland-coronavirus-antiviral-treatment-covid-19/10014437017:06
de-facto.title https://www.cell.com/molecular-therapy-family/molecular-therapy/fulltext/S1525-0016(21)00256-217:09
Brainstormde-facto: From www.cell.com: A SARS-CoV-2 targeted siRNA-nanoparticle therapy for COVID-19: Molecular Therapy17:10
ketasoh, i managed to get appointment next week for nice biontech shot17:18
BrainstormNew from The Indian Express (Health): Health: Plasma therapy: Milind Soman shares he ‘didn’t have enough antibodies’ for donation → https://is.gd/4d5Ija17:27
BrainstormNew from BBC Health: (news): Covid-19: Variant fears could delay England's 21 June easing review → https://is.gd/Xn3Biy17:37
-RSSBot[LjLmatrix- Feed: Consiglio dei Ministri n. 19 ( https://www.governo.it/it/articolo/consiglio-dei-ministri-n-19/16867 )17:58
-RSSBot[LjLmatrix- Feed: Convocazione del Consiglio dei Ministri n. 19 ( https://www.governo.it/it/articolo/convocazione-del-consiglio-dei-ministri-n-19/16869 )17:58
BrainstormNew from Derek Lowe: @RLCscienceboss: RT by @Dereklowe: So maybe all the fuss about mRNA vaccines being incredibly fragile and unstable wasn't really worth the fuss? After more testing, Pfizer and BioNTech determine that their COVID-19 shot is stable at 2-8°C (fridge temp) for a month (up from 5 days). [... want %more?] → https://is.gd/12Wckv18:10
BrainstormNew from r/Coronavirus: Coronavirus: I am Dr. Alex Spyropoulos, a blood clot expert at Northwell Health in NYC. I have been working in one of the epicenters of the COVID-19 pandemic and even recovered from it myself. I specialize in thromboembolic disorders and involved in several research studies on COVID-19 and blood clotting. AMA! → https://is.gd/lxgzls18:21
BrainstormNew from The Lancet (Online): [Comment] Targeting IL-6 in patients at high cardiovascular risk: The understanding that atherosclerosis is a chronic inflammatory disorder mediated through both adaptive and innate immunity has led to the hypothesis that anti-cytokine therapies targeting interleukin signalling pathways could serve as adjuncts to lipid [... want %more?] → https://is.gd/jOVGXQ18:31
LjLOh lord, Sanofi and GSK claiming their vaccine does work, bad viiibes18:33
ArsaneritWhy is it bad if their vaccine works?18:34
LjLWell it's not if it does work, but early tests were underwhelmingly bad, to the point that I thought their offers to help produce Pfizer were because they had given up on their own vaccine18:35
LjLI feel a bit burned from AZ's shenanigans so I'm wary of other companies overselling a meh vaccine18:36
ArsaneritI got my first Comirnaty jab yesterday.18:38
LjLAlso I really wish we stuck with the things that have a 95% or so efficacy level especially given it goes down with variants, so I hope it's not a "barely above 50%" thing they managed to pull to pass approval minimum18:38
LjLCongratulations18:39
ArsaneritMy shoulder hurts.  Otherwise all is fine.18:39
de-factohttps://www.youtube.com/watch?v=o1s6Kucd2_c  Spahn für Ende der Impfpriorisierung | Pressekonferenz18:42
BrainstormNew from BBC Health: How many cases in your area?: Explore the data on coronavirus in the UK and find out how many cases there are in your area. → https://is.gd/8rLBbe18:42
de-facto"According to plans by Federal Health Minister Jens Spahn (CDU), from June 7th, there will no longer be any prioritization with a fixed sequence for corona vaccinations in Germany"18:42
de-factoQuestion for Spahn: if production rates are the limiting factor because they cant saturate the demand, what will be the effect of dropping prioritizing?18:43
de-factoHint: later vaccinations for the risk groups lead to more fatal progressions...18:44
LjLde-facto: well what will the latest age group have been by June 7?18:51
LjLAnd maybe they expect so many Pfizer deliveries that there won't be a supply problem, I dunni18:52
CoronaBot/r/covid19: Neutralizing antibody levels are highly predictive of immune protection from symptomatic SARS-CoV-2 infection (80 votes) | https://www.nature.com/articles/s41591-021-01377-8 | https://redd.it/nefpli18:53
BrainstormUpdates for Andorra: +45 cases (now 13555) since 2 days ago — Canada: +2687 cases (now 1.3 million) since 22 hours ago19:01
de-factoArsanerit, i am curious, how was are you feeling?19:02
de-factosore deltroid muscle and fatigue?19:03
BrainstormNew from r/WorldNews: worldnews: 50 Doctors Reported Dead In 1 Day From Covid Across India: Medical Body → https://is.gd/y9dt6k19:04
vaiooh shit19:05
de-facto:/19:05
de-factoLjL, maybe they want to generate a competitive fight over the limited supply of vaccinations to keep citizens motivated? that would be quite gross imho19:08
de-factotbh i dont want to be a medical doctor on 7th of june19:09
de-factothey will have to fight with their patients about who is going to get the doses that are available19:09
de-factohow about Spahn allowing medical doctors to bill "vacine dispute argument" as service for the patients registered with the office of a medical doctor?19:13
de-facto(sorry about the sarcasm)19:13
BrainstormNew from BBC Health: Covid: Indian variant cases in 86 council areas - Hancock: It's not just Bolton and Blackburn, says the health secretary, as he urges people to get vaccinated. → https://is.gd/IgRteu19:15
de-factolol how about *supplying* vaccines?19:15
de-factothose politicians all are beyond stupid.19:16
BrainstormNew from Politico: US will send 20M more vaccine doses overseas: The announcement followed a Biden administration decision last month to send 60 million Oxford/AstraZeneca doses across the world. → https://is.gd/0Xi1TF19:25
de-factofinally US is exporting19:35
int3restedde-facto: exporting as in?19:35
de-factothe headline from Brainstorm above19:37
de-factoNew from Politico: US will send 20M more vaccine doses overseas: The announcement followed a Biden administration decision last month to send 60 million Oxford/AstraZeneca doses across the world. → https://is.gd/0Xi1TF19:38
de-factojust a minute before you joined the channel19:38
-RSSBot[LjLmatrix- Feed: Il Presidente Draghi al vertice sulle economie africane a Parigi ( https://www.governo.it/it/articolo/il-presidente-draghi-al-vertice-sulle-economie-africane-parigi/16870 )19:38
BrainstormUpdates for Myanmar: +32 cases (now 143097), +1 deaths (now 3213) since a day ago19:39
int3restedde-facto: cool, thanks!19:39
BrainstormNew from Reddit (test): Covid2019: The U.S. will share an additional 20 million doses of domestically authorized coronavirus vaccines with the rest of the world by the end of June → https://is.gd/8VdtAb20:10
BrainstormUpdates for Isle of Man: +1 cases (now 1591) since 14 days ago — Eritrea: +24 cases (now 3868), +2 deaths (now 14) since a day ago20:41
ynhttps://www.wfmj.com/story/43901748/how-to-register-for-ohios-vaxamillion20:54
BrainstormNew from Gazzetta Ufficiale italiana: DELIBERA DEL CONSIGLIO DEI MINISTRI 29 aprile 2021: Dichiarazione dello stato di emergenza per intervento  all'estero  inconseguenza del rischio sanitario connesso all'incremento di  contagida Covid-19 nella Repubblica dell'India. (21A02947) → https://is.gd/CZs29c21:05
BrainstormUpdates for Haiti: +87 cases (now 13460) since 13 hours ago21:06
Arsaneritde-facto: At first I felt fatigue and a bit dizzy.  The fatigue lasted all day, but the dizziness went.  During the day I started to have pain in the shoulder, which remains (less so) the following day.21:16
de-factomakes sense, that is what i heard from most that i asked21:17
de-factowould you say its more or less compared to what you were used to by other vaccinations?21:17
ArsaneritI've not had many other vaccinations that I remember.21:26
ArsaneritI had one as a teenager and one other an as adult, and the side effects of this one were much stronger.21:27
BrainstormNew from CIDRAP: COVID-19 Scan for May 17, 2021: Homeless people with COVID-19 COVID reinfection in college → https://is.gd/CWgv9t21:27
ArsaneritI'm happy to have the privilege to get vaccinated 1-2 months before the majority of the adult population, though.21:27
de-factointeresting well the immune system gets annoyed by the s-protein production, thats kinda of the goal, i wish i also could get it already21:30
de-factobecause those side effects are much better known and controllable compared to COVID21:31
de-factoand its either vaccination or COVID, neither is not realistic unfortunately (hence no vaccination means some form of COVID is guaranteed at some time)21:32
BrainstormUpdates for Sri Lanka: +2456 cases (now 145202) since 15 hours ago — Spain: +11061 cases (now 3.6 million), +93 deaths (now 79432) since 3 days ago — France: +51 deaths (now 107623) since 19 hours ago21:37
gigasu_shidaif you feel chills and aches and pains after vaccination, just know that the real symptoms of a covid infection would've likely been 10x worse21:39
ArsaneritToday I got my first International Certificate of Vaccination or Prohphylaxis (the yellow booklet by WHO standard).  In The Netherlands, childhood vaccinations go in another booklet, and I didn't have adult vaccinations.  There is a column for "COVID-19" in each of the sections for infants, children, adolescents, and adults.21:39
Arsaneritgigasu_shida: That sounds plausible, but is it true?21:39
ArsaneritIn other words: would people who feel more side effects from the vaccine have had worse symptoms from a real infection, and would people who feel less side effects from the vaccine have less symptoms from a real infection?21:40
-RSSBot[LjLmatrix- Feed: Comunicato stampa del Consiglio dei Ministri n. 19 ( https://www.governo.it/it/articolo/comunicato-stampa-del-consiglio-dei-ministri-n-19/16872 )21:43
BrainstormNew from WebMD: Biden: U.S. to Send U.S.-Approved Vaccines Abroad: The White House will send 20 million doses of the Moderna, Pfizer, and Johnson & Johnson vaccines, in addition to the 60 million doses of the AstraZeneca vaccine already set for shipment to other countries. → https://is.gd/7LbhUH21:49
gigasu_shidayeah i don't know Arsanerit, i shouldn't have said that21:52
ArsaneritI certainly take the disease seriously.  More so than during the first wave; in particular the prospect of Long Covid scares me.21:54
gigasu_shidathe propensity for organ damage scares me21:56
gigasu_shidathe potential for*21:56
ArsaneritYes, me too.  I'm lucky to get the vaccine before many others.22:08
de-factohmm i think we cant draw a direct conclusion between reactogenicity and potential for more intense symptomatic covid22:09
de-facto*direct connection22:11
de-factoArsanerit, btw be extra careful now, some of your immune cells might be slightly depleted in the first week of vaccination the probability to catch it is *increased*22:14
de-factofirst protection only slowly starts to be visible like after 14 days primer shot22:14
de-facto.title https://www.medrxiv.org/content/10.1101/2020.12.09.20245175v1.full-text  https://www.nejm.org/doi/full/10.1056/NEJMoa2034577  https://www.nejm.org/doi/10.1056/NEJMoa210176522:22
BrainstormNew from CIDRAP: Retailers, states grapple with shifting COVID-19 mask mandates: Stephanie Soucheray | News Reporter | CIDRAP News May 17, 2021 For the first time since the pandemic started, all states are reporting declining cases. → https://is.gd/OYKLKZ22:22
Brainstormde-facto: From www.medrxiv.org: BNT162b2 induces SARS-CoV-2-neutralising antibodies and T cells in humans | medRxiv22:22
Arsaneritde-facto: increased, really?22:28
ArsaneritI wasn't told that.  I was just told full protection is not until two weeks after the second dose.22:29
ArsaneritI'm exactly as careful as I was before my first dose, which means rather careful.22:29
ArsaneritAlthough I did visit the doctor today, which involved sitting in a doctor's office waiting room; and the vaccination centre itself is the busiest place I've visited in the past year.  But all were keeping good distance (except the doctor) and wearing (mostly FFP2) masks.22:30
de-factoyeah then you will be just fine as everyone else that did the same thing22:32
de-factoits only a small effect anyhow, just continue to be careful, the past proved that you prevented exposing yourself22:33
BrainstormNew from StatNews: STAT+: FDA issues major rebuke to CytoDyn over claims on Covid-19 drug: The FDA took the extraordinary step of issuing a lengthy statement on an unapproved drug, rejecting claims made by the drug maker CytoDyn about its failed antibody treatment for Covid-19. → https://is.gd/qz8QJg22:33
BrainstormNew from COVID19 Vaccine Tracker: Shannon McKearnan: Aivita Biomedical Inc: AV-COVID-19 → https://is.gd/qrWy9m22:55
BrainstormNew from WebMD: Questions Still Swirl Around New CDC Mask Guidance: CDC Director Rochelle Walensky, MD defends the policy after the agency announced that fully vaccinated people no longer need to wear masks for indoor and other activities. → https://is.gd/Q87hFr23:06
BrainstormUpdates for Switzerland: +8 deaths (now 10744) since 7 hours ago23:10
gigasu_shidadoes anyone know how the genose virus tests work?23:14
de-factohttps://en.wikipedia.org/wiki/Coronavirus_breathalyzer23:21
de-factohttps://www.ugm.ac.id/en/search/index/?s=genose23:25
de-facto.title https://www.sciencedirect.com/science/article/pii/S221418042030101X23:28
Brainstormde-facto: From www.sciencedirect.com: Deep learning in a sensor array system based on the distribution of volatile compounds from meat cuts using GC–MS analysis - ScienceDirect23:28
de-factois it that one there?23:28
de-factowould be interesting to know which sensors they would use for detecting COVID23:31
de-factoi guess in that paper there they only describe such type of technology bug for other purpose23:31
de-facto.title https://www.medrxiv.org/content/10.1101/2020.06.21.20136523v1.full-text <-- another paper about breath markers in COVID23:37
Brainstormde-facto: From www.medrxiv.org: Breath-borne VOC Biomarkers for COVID-19 | medRxiv23:37
de-factohence my guess would be that is how their system works: they probably have a sensor array detecting substances in exhale that change by ongoing COVID hence employ a neuronal network for pattern recognition in the output spectrum of all those sensors combined to recognize the characteristic pattern that would correlate with a COVID case confirmed by a second method (e.g. via PCR test)23:40
de-factoyet then that makes me wonder about their detection rates over time23:44
de-factoa very early infection, days before symptom onset, let alone affecting bigger surface areas (such as the lung itself), how much would it affect the spectrum of molecules contained in exhalation?23:46
de-factoyet at that stage, could a gargle or cotton swab sample not already collect enough RNA to go over the detection threshold in a PCR test below the maximum number of cycles?23:47
de-factobut then there is the advantage of direct result with a local device, so every case they find with such electronic noses, that probably will be confirmed then by PCR later is a win because it would end further potential infection chains in the future of that case23:48
CoronaBot/r/coronavirus: Target lifts face mask requirement, unless local rules state otherwise (10005 votes) | https://bringmethenews.com/minnesota-lifestyle/target-lifts-its-face-mask-requirement-unless-local-rules-state-otherwise | https://redd.it/nefjup23:49
de-factoyet i fear, as unfortunately reality teaches the optimist, humans might take a negative test result as confirmation for their wishes (not to be infected) and then happily drop distancing etc, a phenomena unfortunately already seen by the introduction of the (not so sensitive) rapid antigen quicktests23:51
de-factoso as long as a negative result from a technology that is not so sensitive is treated accordingly (as potential false negative of an early infection) i guess it can be quite helpful with testing and finding more positive results and thereby removing them from the pool of infectious in a population23:53
de-factoeven if specificity would be not super high, those always can be cross-checked by some highly specific tests such as PCR, as long as false positive rates are not high enough to undermine the trust in a testing technology23:55
de-factoyet instant testing can increase testing rates significantly, especially with smart technologies that would not produce much disposables (or none at all!)23:57
de-factoso if that electronic nose technology works it probably can be a great help if used appropriately to its capabilities and specs23:57

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