| Brainstorm | Updates for Rwanda: +298 cases (now 28912) since 23 hours ago | 00:34 |
|---|---|---|
| Brainstorm | Updates for Zimbabwe: +241 cases (now 40318), +2 deaths (now 1637) since 22 hours ago | 00:59 |
| Brainstorm | New from FDA Press Releases: FDA: Coronavirus (COVID-19) Update: June 15, 2021 → https://is.gd/sxU5T0 | 01:05 |
| Brainstorm | New from r/WorldNews: worldnews: New NIH study says the coronavirus was present in five states in December 2019 → https://is.gd/jWfg5o | 01:56 |
| Brainstorm | Updates for Ghana: +206 cases (now 94699), +1 deaths (now 790) since 2 days ago | 02:01 |
| Brainstorm | New from Shane Crotty: @RolandBakerIII: RT by @profshanecrotty: Derek Lowe's blog updates his opinion on Ivermectin trials indicating lack of evidence of effectivenessScience: Ivermectin As a COVID-19 Therapyhttps://blogs.sciencemag.org/pipeline/archives/2021/06/07/ivermectin-as-a-covid-19-therapy → https://is.gd/3D5idL | 02:37 |
| Brainstorm | Updates for Reunion: +1206 cases (now 28441), +8 deaths (now 220) since 6 days ago — United Kingdom: +5681 cases (now 4.6 million), +6 deaths (now 128044) since 21 hours ago — Netherlands: +477 cases (now 1.7 million), +2 deaths (now 17852) since 21 hours ago | 02:38 |
| LjL | <CarlSagan_> [Ars Technica - Science] Experts “extremely worried” about Delta variant as US death toll hits 600,000 https://arstechnica.com/?p=1773877 2021-06-15T23:55:09 | 03:07 |
| Brainstorm | New from r/WorldNews: worldnews: N.Korea's Kim says food situation 'tense' due to pandemic, typhoons → https://is.gd/Ba6lZs | 03:29 |
| Brainstorm | Updates for Ivory Coast: +149 cases (now 47909) since a day ago | 03:40 |
| Brainstorm | New from Reddit (test): CoronaVirus_2019_nCoV: Florida nursing homes report COVID-19 infection rates nearly double the national average - The Florida AARP says that 19% of Florida nursing homes are reporting new COVID-19 cases in the last four weeks. → https://is.gd/rKon5Z | 04:00 |
| Brainstorm | Updates for Cayman Is.: +6 cases (now 599) since a day ago | 04:30 |
| Brainstorm | New from Virology.ws: Trial By Error: #MEAction’s Chronic Illness Survey; Patients’ Research Informs CDC’s Long-COVID Advice: By David Tuller, DrPH New survey to assess links between chronic conditions Jaime Seltzer, #MEAction’s Director of Scientific & Medical Outreach, has been pretty busy lately. This week, she appeared on a panel at the [... want %more?] → https://is.gd/bKw1Za | 04:32 |
| Brainstorm | New from The Indian Express: World: UK ministers to be advised against mass vaccination for children – The Telegraph → https://is.gd/so4FKz | 04:42 |
| Brainstorm | Updates for United Kingdom: +5694 cases (now 4.6 million), +8 deaths (now 128047) since 21 hours ago — France: +38 deaths (now 110561) since 21 hours ago — Netherlands: +519 cases (now 1.7 million) since 21 hours ago — Canada: +1289 cases (now 1.4 million) since 21 hours ago | 05:07 |
| Brainstorm | New from The Indian Express: World: Ecuador authorizes use of China’s CanSino vaccine against COVID-19 → https://is.gd/1V6TUI | 05:23 |
| Brainstorm | Updates for Mexico: +4250 cases (now 2.5 million), +172 deaths (now 230346) since 23 hours ago — Benin: +31 cases (now 8140), +1 deaths (now 103) since 6 days ago | 05:32 |
| Brainstorm | New from The Indian Express: World: North Korea’s Kim says food situation ‘tense’ due to pandemic, typhoons → https://is.gd/QS6bzm | 06:05 |
| Brainstorm | Updates for Belgium: +508 cases (now 1.1 million), +6 deaths (now 25099) since a day ago | 06:10 |
| Brainstorm | New from The Indian Express (Health): Health: Covid-19 and oral health: Here’s what you can do for dental hygiene → https://is.gd/8llO2D | 06:37 |
| Brainstorm | New from StatNews: Regeneron antibody saves lives in some hospitalized Covid patients, study finds: A monoclonal antibody treatment for Covid-19 developed by Regeneron saved lives among hospitalized patients who had not mounted their own immune response, researchers said in an important new finding. → https://is.gd/voM1rp | 07:07 |
| Brainstorm | New from BBC Health: Another life-saving Covid treatment found: Monoclonal antibody therapy, given by drip, can save some of the sickest hospital patients. → https://is.gd/gndnTH | 07:28 |
| Brainstorm | Updates for Unknown, Colombia: +24452 cases (now 77347), +369 deaths (now 892) since a day ago — Sao Paulo, Brazil: +23227 cases (now 3.5 million), +897 deaths (now 119110) since a day ago — Mongolia: +2395 cases (now 83128), +9 deaths (now 389) since 23 hours ago — India: +62224 cases (now 29.6 million), +2603 deaths (now 378735) since 23 hours ago | 07:37 |
| Brainstorm | New from r/WorldNews: worldnews: Taiwanese flying to US, China for vaccines as island's Covid-19 situation worsens → https://is.gd/EZolIm | 08:09 |
| Brainstorm | Updates for El Salvador: +946 cases (now 76297) since 23 hours ago | 08:39 |
| Brainstorm | New from The Indian Express: World: China ramps up vaccinations, but uneven rollout leaves borders closed → https://is.gd/UPzya5 | 08:51 |
| Brainstorm | New from r/Coronavirus: Daily Discussion Thread | June 16, 2021: Please refer to our Wiki for more information on COVID-19 and our sub. You can find answers to frequently asked questions in our FAQ , where there is valuable information such as our: → https://is.gd/EEKsLl | 09:11 |
| Brainstorm | Updates for Kyrgyzstan: +647 cases (now 111990), +7 deaths (now 1912) since a day ago — Uzbekistan: +350 cases (now 104463), +2 deaths (now 711) since a day ago | 09:41 |
| Brainstorm | New from Politico: Coronavirus: Coronavirus vaccines to be mandatory for England’s care workers → https://is.gd/1t1GV7 | 09:43 |
| Brainstorm | Updates for St. Kitts and Nevis: +35 cases (now 244) since a day ago — British Virgin Islands: +3 cases (now 295) since 13 days ago — St. Pierre and Miq.: +1 cases (now 26) since 13 days ago | 10:30 |
| Brainstorm | New from StatNews: Sewage sleuths helped an Arizona town beat back Covid-19. For wastewater epidemiology, that’s just the start: As the pandemic spread, hundreds of cities, states, prisons, universities, and private businesses leaped into wastewater surveillance. The question now is, what will they do with all that surveillance infrastructure? → https://is.gd/HQCgJQ | 10:35 |
| Brainstorm | New from The Indian Express: World: California celebrates reopening as many pandemic rules end → https://is.gd/ZmwQjD | 11:07 |
| Brainstorm | New from BMJ: David Oliver: Deaths from hospital acquired covid are everyone’s problem: Last month the Guardian reported that, since March 2020, “Up to 8700 patients died after catching covid-19 in English hospitals.”1 The question is whether any of these cases could have been avoided... → https://is.gd/RxB9hq | 11:39 |
| Brainstorm | New from WHO Euro: Breakthrough WHO initiative launched in Europe to engage and empower civil society organizations in health emergency responses: Throughout the pandemic, civil society organizations (CSOs) have been crucial partners in reducing the impacts of COVID-19 on individuals and communities, particularly those in hard-to-reach vulnerable [... want %more?] → https://is.gd/7qSmcA | 11:59 |
| Brainstorm | New from ScienceNews: Moral judgments about an activity’s COVID-19 risk can lead people astray: People use values and beliefs as a shortcut to determine how risky an activity is during the pandemic. Those biases can lead people astray. → https://is.gd/u8Yz3h | 12:10 |
| Brainstorm | New from The Indian Express: World: Many post-Covid patients are experiencing new medical problems, study finds → https://is.gd/khdWH6 | 12:31 |
| Brainstorm | Updates for Indonesia: +9944 cases (now 1.9 million), +196 deaths (now 53476) since 23 hours ago | 12:35 |
| Brainstorm | New from Scientific American: COVAX Effort to Vaccinate the World is Faltering: Idlib Health Directorate workers in Syria receive 53,800 doses of COVID-19 vaccines sent via the COVAX program for global equitable access. → https://is.gd/vZZ1PH | 12:51 |
| Brainstorm | New from The Indian Express (Health): Destination of the week: Tourists delighted after Taj Mahal reopens after two months → https://is.gd/Zxnfgn | 13:02 |
| Brainstorm | New from New Scientist: Antiviral drug shown to save lives of covid-19 patients in hospital: In patients with severe covid-19 who had no natural antibody response, a therapy containing two antibodies reduced mortality by a fifth → https://is.gd/OxexWf | 13:33 |
| Brainstorm | Updates for Senegal: +68 cases (now 42118) since a day ago — Switzerland: +3 deaths (now 10867) since 23 hours ago | 14:39 |
| Brainstorm | New from Reddit (test): nCoV: Exposure To Common Cold Virus May Protect From COVID-19: Study | Link to study in comments | 16JUN21 → https://is.gd/p9x7RS | 14:46 |
| Brainstorm | New from The Indian Express (Health): Health: DiabetesIndia shares advisory for treatment of Covid patients on steroids → https://is.gd/yneSPJ | 14:56 |
| Brainstorm | Updates for Fiji: +121 cases (now 1443) since a day ago — Nepal: +2014 cases (now 614216), +52 deaths (now 8558) since 23 hours ago | 15:04 |
| Brainstorm | New from Reddit (test): China_Flu: Former CDC Head: WHO ‘Too Compromised’ to Conduct COVID-Origin Probe → https://is.gd/tsULY2 | 15:17 |
| Brainstorm | New from StatNews: Pharma: STAT+: Pharmalittle: Regeneron Covid-19 drug cuts risk of death in some patients; bills reintroduced to help develop new antibiotics → https://is.gd/cWytIS | 15:27 |
| Brainstorm | New from BBC Health: Covid: Children aged 12-17 unlikely to be offered vaccine in UK: Some groups of children may be vaccinated - but not all, the UK's vaccine experts are expected to say. → https://is.gd/iphxoL | 15:48 |
| Brainstorm | New from NPR: Royal Caribbean's Launch Of Its New Megaship Just Got Sidelined By COVID Cases: The Odyssey of the Seas had been slated to carry passengers for the first time on July 3. Instead, all 1,400 crew members are being quarantined. → https://is.gd/0GrTFb | 16:09 |
| Brainstorm | Updates for Bangladesh: +3956 cases (now 837247), +60 deaths (now 13282) since a day ago | 16:31 |
| Brainstorm | New from r/WorldNews: worldnews: [Euronews] France lifts requirement to wear a face mask outdoors in public and stops nighttime curfew early → https://is.gd/BUKZbm | 16:41 |
| de-facto | .title https://www.medrxiv.org/content/10.1101/2021.06.11.21258690v1 | 16:53 |
| Brainstorm | de-facto: From www.medrxiv.org: Brain imaging before and after COVID-19 in UK Biobank | medRxiv | 16:53 |
| de-facto | ugh thats scary :( | 16:53 |
| LjL | yikes | 16:55 |
| Mikaela | I am too scared of clicking and probably happy to have gotten the first doze of Pfizer today | 16:55 |
| LjL | they should do it with people who've taken the vaccine though, to quench "it crosses the blood-brain barrier" fears ;( | 16:55 |
| LjL | bad timing | 16:56 |
| Mikaela | ? | 16:56 |
| LjL | for my remark | 16:57 |
| Mikaela | oh | 16:58 |
| de-facto | maybe related could be another preprint | 17:01 |
| de-facto | .title https://www.medrxiv.org/content/10.1101/2020.10.20.20215863v1 | 17:01 |
| Brainstorm | de-facto: From www.medrxiv.org: Cognitive deficits in people who have recovered from COVID-19 relative to controls: An N=84,285 online study | medRxiv | 17:01 |
| Brainstorm | New from WebMD: Fewer Dangerous COPD Flare-Ups During COVID: A new study finds the health precautions used to combat spreading COVID may also have helped those with COPD. → https://is.gd/Emazam | 17:02 |
| LjL | de-facto, one comment says "Drawing any conclusions from a paper in which of 84,000 + people less than .5% actually had evidence ( 361 reported having had a positive biological test) of covid infection seems optimistic." and that's consistent with the abstract saying "We analysed cognitive test data from 84,285 Great British Intelligence Test participants who completed a questionnaire regarding suspected and biologically confirmed COVID-19 infection." | 17:04 |
| LjL | if really the amount of confirmed cases is so small, i'd feel no qualm saying the study is trash | 17:04 |
| LjL | the other one on the other hand... | 17:05 |
| LjL | especially because the findings are consistent with loss of smell and taste | 17:05 |
| de-facto | i havent looked into the details of the second study, i just remembered that it was linked here before | 17:06 |
| de-facto | i am still reading the first preprint that shows shrinking of brain regions for COVID+ compared to COVID- | 17:06 |
| LjL | <Brainstorm> New from Reddit (test): Covid2019: India: Another lion dies at Chennai zoo due to Covid-19 → https://is.gd/OCG25P | 17:15 |
| LjL | but somehow they can't pass it back to humans... i still don't believe it | 17:15 |
| Brainstorm | Updates for Iraq: +5139 cases (now 1.3 million), +19 deaths (now 16781) since 23 hours ago — Switzerland: +282 cases (now 701260) since 2 hours ago — Canada: +18 deaths (now 25959) since 23 hours ago | 17:33 |
| Brainstorm | New from The Indian Express (Health): Life-style: Giant Buddhist goddess in Japan gets face mask to pray for end of Covid-19 → https://is.gd/P6AwY5 | 17:55 |
| Brainstorm | Updates for United Kingdom: +4089 cases (now 4.6 million) since 15 hours ago | 18:10 |
| Brainstorm | Updates for Portugal: +1350 cases (now 860395), +6 deaths (now 17055) since 23 hours ago — Gibraltar: +3 cases (now 4315) since 3 days ago | 18:35 |
| Brainstorm | New from r/WorldNews: worldnews: Covid vaccine to be compulsory for England care home staff → https://is.gd/NFg0F0 | 18:46 |
| Brainstorm | New from In The Pipeline: Chose Your Controls Wisely: I’ve been meaning to write about this paper (open access) on some problems with chemical probes, and now’s a good time. There was a well-known article a few years ago about “The Promise and Peril of Chemical Probes”, and this is a deliberate follow-up, starting with its title. Even if you [... want %more?] → https://is.gd/NSc7hy | 18:57 |
| Brainstorm | Updates for Mozambique: +113 cases (now 71764), +2 deaths (now 844) since 22 hours ago | 19:00 |
| Brainstorm | New from r/WorldNews: worldnews: Extreme poverty jumps in Italy on back of COVID woes → https://is.gd/3b5yiD | 19:28 |
| LjL | :( | 19:31 |
| Brainstorm | Updates for Italy: +1400 cases (now 4.2 million), +52 deaths (now 127153) since 21 hours ago | 19:37 |
| Brainstorm | New from EuroNews: (news): Portugal's COVID recovery plan is first to receive Brussels' approval → https://is.gd/6loQQN | 19:49 |
| Brainstorm | Updates for Switzerland: +1 deaths (now 10868) since 5 hours ago | 20:02 |
| Brainstorm | New from ScienceMag: [Research Articles] Plasma from patients with bacterial sepsis or severe COVID-19 induces suppressive myeloid cell production from hematopoietic progenitors in vitro: Bacterial sepsis and severe COVID-19 share similar clinical manifestations and are both associated with dysregulation of the myeloid cell compartment. We previously [... want %more?] → https://is.gd/bl2d7e | 20:20 |
| Brainstorm | Updates for Morocco: +500 cases (now 524975), +4 deaths (now 9221) since a day ago — Spain: +3832 cases (now 3.7 million), +36 deaths (now 80615) since 22 hours ago — Canada: +11 deaths (now 25965) since 21 hours ago | 20:39 |
| Brainstorm | New from r/WorldNews: worldnews: Couple who snuck into Yukon community for vaccine pleads guilty to breaking pandemic rules → https://is.gd/wrbu7U | 20:42 |
| Brainstorm | Updates for South Africa: +13246 cases (now 1.8 million), +136 deaths (now 58223) since 22 hours ago — N. Cyprus: +62 cases (now 7622) since a day ago | 21:04 |
| Brainstorm | New from r/WorldNews: worldnews: Jon Stewart tells Colbert it's obvious COVID-19 came from Wuhan lab → https://is.gd/v4lwJr | 21:24 |
| Brainstorm | Updates for India: +63569 cases (now 29.6 million) since 23 hours ago | 21:29 |
| Brainstorm | New from CIDRAP: News Scan for Jun 16, 2021: Nursing home COVID disparities COVID-19 and work-life balance Avian flu in 2 countries → https://is.gd/I6Iv84 | 21:34 |
| FSR[m] | hello, anyone knows about something I heard before about: | 22:01 |
| FSR[m] | a update to the vaccine found in german lab | 22:01 |
| FSR[m] | which makes the vaccine get released to the body slowly? | 22:01 |
| shayan_doust | Sounds interesting. I haven't heard of it | 22:03 |
| Brainstorm | New from CIDRAP: VA must modernize supply chain after COVID-19, GAO says: Lianna Matt McLernon | News Writer | CIDRAP News Jun 16, 2021 GAO's latest report looks at the VA's three main supply chain, COVID-related adaptations. → https://is.gd/nFB7SM | 22:06 |
| Brainstorm | Updates for Zambia: +3026 cases (now 118850), +48 deaths (now 1492) since a day ago | 22:06 |
| LjL | FSR[m], CureVac? | 22:19 |
| nixonix | what was the link again about increased cell infectivity i said i will read the next day? | 22:25 |
| LjL | nixonix, <de-facto> .title https://science.sciencemag.org/content/early/2021/05/24/science.abi5273 <-- Fig 3 shows roughly 1 log10 difference between B.1.1.7 and non-B.1.1.7 viral loads | 22:26 |
| Brainstorm | New from CIDRAP: CDC: Delta variant now 10% of US COVID-19 cases: Stephanie Soucheray | News Reporter | CIDRAP News Jun 16, 2021 In other developments, the CDC added Delta as a variant of concern and issued its first guidance on 'long COVID'. → https://is.gd/GGuNXH | 22:27 |
| nixonix | ok, it was that one i just had a look. i thought it was about 614g compared to older variants, so i confused | 22:27 |
| LjL | nixonix, btw, palasso seems to be happily on the "new freenode" | 22:28 |
| nixonix | here or there? | 22:29 |
| LjL | there, meaning the freenode run by Lee, but no longer the one running ircd-seven (because it stopped existing yesterday, but he was there too while it lasted) | 22:29 |
| nixonix | i havent checked its pol channels yet after the change, but where theres more freedom of speech, those who like it will prob go there | 22:32 |
| nixonix | i remember some channels forced out | 22:32 |
| LjL | i understand feeling constrained on Libera, but the other place is utter madness right now, well, it has been for days. i can't understand how anybody reasonable and with a clue about what's happening would choose it. | 22:32 |
| LjL | just join and follow #freenode for a while, although it's not even as bad as when rasengan is around | 22:33 |
| nixonix | ill check some day when im more to ircing again | 22:33 |
| nixonix | into | 22:33 |
| nixonix | anyways, just not to leave wrong impression about that s-protein toxicity last time, it seems it has harmfull effect itself, but just that with mrna vaccines the concentrations are about 1M times lower than with acute infection | 22:35 |
| nixonix | and its not even confirmed, are they whole s-proteins or just fragments | 22:35 |
| nixonix | *if they are | 22:35 |
| nixonix | also: "This conclusion suggests that vaccination-generated antibody and/or exogenous antibody against S protein not only protects the host from SARS-CoV-2 infectivity but also inhibits S protein-imposed endothelial injury | 22:37 |
| LjL | nixonix, but there are reports of myocarditis now in a small number of younger people getting mRNA vaccines (well, Pfizer/BNT) at least, could S-proteins acting naughty with cardiac cells be a mechanism? | 22:38 |
| nixonix | it looks like binding of spike to cell's ace2 itself causes mitochondrial reactive oxygen species production. but its really a problem with infection | 22:39 |
| nixonix | i havent even thought about that mechanism, hmm | 22:39 |
| nixonix | prob not, its so minor with mrna vaccines | 22:40 |
| nixonix | so its prob due to immune reaction | 22:40 |
| nixonix | and possibly with exercise, like when exercising when in flu | 22:41 |
| LjL | nixonix, oh, that's a no-no? | 22:42 |
| nixonix | those vaccines will cause increased pro-inflammatory cytokine production, depending on vaccine | 22:42 |
| nixonix | i wouldnt do it during the following days, esp after the 2nd dose | 22:42 |
| LjL | good to know | 22:44 |
| LjL | i treadmilled a bit after the first dose, since i had no side effects at all | 22:45 |
| LjL | (Pfizer) | 22:45 |
| LjL | well, except for mild injection site pain which i take for granted | 22:45 |
| nixonix | https://ir.novavax.com/news-releases/news-release-details/novavax-covid-19-vaccine-demonstrates-90-overall-efficacy-and | 22:46 |
| LjL | right, Novavax looks nice, but i think they need to license production to someone | 22:48 |
| Brainstorm | New from StatNews: Pharma: STAT+: American Medical Association delegates vote to support controversial Covid-19 IP waiver → https://is.gd/FiSlrO | 22:48 |
| LjL | nixonix, press releases always tend to leave me perplexed though. how can it have 90.4% overall efficacy when it has *higher* efficacy against populations at risk and variants of interest/concern? | 22:50 |
| nixonix | they have a production problem. not sure if its all about bioreactor bags, but just read that eu plans that they should start to produce them in europe | 22:50 |
| LjL | Seventy-seven cases were observed: 63 in the placebo group and 14 in the vaccine group. ← small sample here unfortunately | 22:50 |
| nixonix | usa hasnt allowed to export those or PEG outside the country (exp possibly when they get part of the produced vaccine) | 22:50 |
| nixonix | derek lowe has a new article on both subjects above | 22:56 |
| nixonix | https://blogs.sciencemag.org/pipeline/archives/2021/06/15/the-novavax-vaccine-data-and-spike-proteins-in-general | 22:56 |
| nixonix | just noticed | 22:56 |
| nixonix | hi indo | 22:57 |
| nixonix | ah, connection going on and off.. | 22:57 |
| -RSSBot[LjLmatrix- Recent Commits to links:master: Add Novavax press release about PREVENT-19 phase 3 trial ( https://github.com/ljl-covid/links/commit/165dd0016fff18d3de88763227c4f7f9acf6bbca ) | 23:08 | |
| Brainstorm | Updates for Curacao: +8 cases (now 12304) since a day ago | 23:08 |
| Brainstorm | New from https://covid19.specops.network : ljl-covid: Add Novavax press release about PREVENT-19 phase 3 trial → https://is.gd/848ap5 | 23:09 |
| nixonix | it seems theres less often whole spikes in sars2 patients plasma than you would think, hmm, maybe due to cleavaging of S1 or just antibodies attaching to them | 23:11 |
| nixonix | that 1M times more when infection was an estimate of some expert, but maybe he didnt have updated info | 23:13 |
| -RSSBot[LjLmatrix- Recent Commits to links:master: Move Novavax to its own section ( https://github.com/ljl-covid/links/commit/258ae61383229cd964e745f15fc6df66c995f065 ) | 23:13 | |
| LjL | nixonix, here's something that makes me definitely want to get the vaccine even if it causes some myocarditis over COVID anyway https://www.medrxiv.org/content/10.1101/2021.06.11.21258690v1 | 23:15 |
| Brainstorm | New from https://covid19.specops.network : ljl-covid: Move Novavax to its own section → https://is.gd/1Bdzm3 | 23:19 |
| nixonix | well, smell seems to be less often affected with 617.2 - at least in uk self symptom reporting system | 23:21 |
| nixonix | the previous best guess seemed to be neurological damage was more likely to be caused by vascular damage than neuroinvasiveness | 23:22 |
| LjL | whichever it is, the scary thing for me is it can be observed even in "mild" non-hospitalized cases | 23:22 |
| nixonix | yeah, and thinking about leaving kids without vaccine, because usually their symptoms are minor | 23:24 |
| LjL | nixonix, in Italy kids 12-15 are being vaccinated after Pfizer trialled for them and was approved | 23:27 |
| LjL | younger than 12, not yet | 23:27 |
| lavadonut | i love being vaccinated | 23:28 |
| lavadonut | i love not getting permanent lung, heart, and brain damage | 23:29 |
| lavadonut | :D | 23:29 |
| nixonix | in france they started or are starting soon too, 12+ | 23:32 |
| LjL | ublx, hi welcome to freenode | 23:33 |
| Brainstorm | Updates for France: +20 deaths (now 110581) since 18 hours ago | 23:33 |
| ublx | wha- | 23:34 |
| ublx | stop confusing me | 23:34 |
| LjL | ublx, i knoooow sorry, this is Matrix | 23:34 |
| ublx | >.> | 23:34 |
| ublx | so freenode dropped the nickserv database. interesting move | 23:35 |
| LjL | ublx, we had a lot of fun (and then it degenerated into spam without any fun) on the last standing ircd-seven server which they couldn't figure out how to shut down for 12 hours or so | 23:36 |
| LjL | i connected to it from my Amiga | 23:36 |
| ublx | lol | 23:36 |
| LjL | there are currently at least two claimed "last messages ever sent" on freenode, one concerning the network with services, and one on this last split server | 23:36 |
| LjL | but i'll go with the former | 23:37 |
| LjL | <girst> fuck you rasengan for destroying freenode <3 | 23:37 |
| nixonix | https://www.rfi.fr/en/france/20210615-france-begins-vaccinating-teenagers-in-difficult-bid-to-reach-herd-immunity-coronavirus | 23:37 |
| LjL | they just said there is a cluster of Delta in Milan ;( | 23:38 |
| nixonix | rasengan seems to be some kind of manga or anime thing (still have to learn which one was comics, which one cartoons) | 23:40 |
| Brainstorm | New from Politico: CureVac’s vaccine only 47 percent effective at preventing COVID: German carried out study of 40,000 people in 10 countries in Europe and Latin America with at least 13 coronavirus variants. → https://is.gd/FhVmC8 | 23:40 |
| nixonix | what, mrna vaccine | 23:40 |
| nixonix | More than half (57 percent) were "variants of concern." | 23:41 |
| nixonix | so what could be the reason, other mrna vaccines actually as bad against the VOCs, or the differences curevac has to them | 23:42 |
| nixonix | less mrna (12 ug vs 30 and 100), different utrs and poly-a's, nanoparticles | 23:43 |
| LjL | wuuuuuuut CureVac | 23:44 |
| nixonix | all of them have proline substitutions, but curevac doesnt use pseudouridines, which shouldnt reduce its efficacy, but rather increase the immune response | 23:44 |
| LjL | nixonix, well if they're all THAT bad then Novavax is like... a miracle | 23:44 |
| LjL | a very small miracle with very small scale production ;( | 23:44 |
| LjL | de-facto, ↑ | 23:44 |
| nixonix | unless it has different type 1/2 helper t-cell response producing reduced humoral response or something | 23:45 |
| LjL | nixonix, i think other mRNA vaccines have proven much better than 47% even at VoCs, at least the UK one... 47% means they did not reach the specified endpoint and so it's a clear-cut failure unfortunately :( | 23:45 |
| LjL | Pfizer had 75% against the Indian variant iirc (or South Africa? i forget) | 23:46 |
| nixonix | i suppose curevacs results are against symptomatic infection | 23:47 |
| nixonix | vs severe it should be better. so what kind of variant shares | 23:48 |
| LjL | i would assume that, since that's the criterion everyone else used | 23:48 |
| LjL | nixonix, it doesn't really matter though if it isn't meeting the endpoint as it won't be approved | 23:48 |
| nixonix | outside uk, prob most were kent variant, and in latin america those variants they have there | 23:50 |
| Brainstorm | New from Gazzetta Ufficiale italiana: MINISTERO DELL'ECONOMIA E DELLE FINANZE - DECRETO 31 maggio 2021: Modalita' tecniche per il coinvolgimento del Sistema TessereSanitaria ai fini dell'estensione e verifica delle attivita' diprenotazione e somministrazione delle vaccinazioni per la prevenzionedelle infezioni da SARS-CoV2 nonche' [... want %more?] → https://is.gd/SNeDlj | 23:50 |
| nixonix | so it looks like its too weak. can still be better than az, but new approved drugs and vaccines are supposed to be at least as good harm/benefit as those already in use | 23:51 |
| LjL | yeah anyone would say "fuck you, i want pfizer", and i'm not sure i could blame them | 23:52 |
| nixonix | if compared variant vs variant its clearly inferior to the current mrna's they cant sacrify the production capacity for that | 23:52 |
| nixonix | sacrifice | 23:53 |
| nixonix | maybe its something like problem with nanoparticles or intact mrna, which could be a production or cold chain problem | 23:55 |
| nixonix | 12 μg vs 30 vs 100 | 23:58 |
| nixonix | damn code what was that | 23:58 |
| nixonix | µ | 23:58 |
| LjL | hmm well but if they used 12 i presume that was the dose that looked optimal from phase 1/2 stuff | 23:59 |
| LjL | but i guess they'll try to tweak the dose or something to at least get past 50% in the next interim or final | 23:59 |
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