| de-facto | genera, https://pbs.twimg.com/media/EYgO5i-WsAEl7Yt?format=jpg&name=large | 00:02 |
|---|---|---|
| genera | boah da weiß ich jetzt schon wovon ich heut nacht schlecht träumen werde | 00:09 |
| de-facto | at least now you know where all the structural proteins are located in the virion :D | 00:10 |
| nixonix | this site had some good images | 00:12 |
| nixonix | https://www.medicalimages.com/imageSearcher.do?keywords=sars-cov-2&isMedical=1&logKeywords=1 | 00:12 |
| nixonix | i once saw a great simulated animation of vibrating s protein, but lost it and never found again. when searching those i found were all inferior to that, but it was around year ago | 00:13 |
| nixonix | it was something like 15ns or so, i think | 00:14 |
| Brainstorm | New from Francois Balloux: @BallouxFrancois: R to @BallouxFrancois: The SARSCoV2 T-cell X-immunity saga has been an interesting journey for me. I initially thought it made sense (and got massive abuse for it). I then changed my views to it being probably anecdotal, and now, I'm essentially back to square one. Science is interesting at times.6/ → https://is.gd/Qt5CqU | 00:20 |
| Brainstorm | Updates for Tunisia: +6776 cases (now 426879), +106 deaths (now 15065) since a day ago — Zimbabwe: +1357 cases (now 51221), +19 deaths (now 1808) since a day ago | 00:37 |
| Brainstorm | New from The Lancet (Online): [Seminar] Acute respiratory distress syndrome: Acute respiratory distress syndrome (ARDS) is an acute respiratory illness characterised by bilateral chest radiographical opacities with severe hypoxaemia due to non-cardiogenic pulmonary oedema. The COVID-19 pandemic has caused an increase in ARDS and highlighted challenges [... want %more?] → https://is.gd/CemQSN | 00:41 |
| nixonix | interesting subject, that balloux's tweet. heres something: | 00:48 |
| nixonix | .title https://www.medrxiv.org/content/10.1101/2020.12.07.20245241v2.full | 00:48 |
| Brainstorm | nixonix: From www.medrxiv.org: Lack of antibodies against seasonal coronavirus OC43 nucleocapsid protein identifies patients at risk of critical COVID-19 | medRxiv | 00:48 |
| Krey[m] | does anyone know how pottery works | 00:50 |
| Krey[m] | x.x | 00:50 |
| pwr22 | Magic | 00:53 |
| pwr22 | 🪄 | 00:54 |
| pwr22 | 🫖 | 00:55 |
| nixonix | some of you may remember those strange t-cell reacivities for 50% of people in singapore, never having sars2 or sars1, and not t-cells associated to hcov's | 00:55 |
| nixonix | originating possibly from exposure to some animal coronaviruses, without actually getting infection | 00:56 |
| nixonix | the same could happen with sars2, exposure without infection, giving perhaps protection too, perhaps not. reactivity doesnt necessrily mean protection, whatever the source for it | 00:57 |
| nixonix | .title https://pubmed.ncbi.nlm.nih.gov/33582369/ | 00:59 |
| Brainstorm | nixonix: From pubmed.ncbi.nlm.nih.gov: Pre-existing T-cell immunity to SARS-CoV-2 in unexposed healthy controls in Ecuador, as detected with a COVID-19 Interferon-Gamma Release Assay - PubMed | 00:59 |
| Krey[m] | <pwr22 "Magic"> ah thanks it all makes sense now, i need a transmutation circle and sacrifice a human to it | 01:11 |
| * Krey[m] uploaded an image: (284KiB) < https://libera.ems.host/_matrix/media/r0/download/matrix.org/CSRtTAKSINeneWIXCMIZKMXu/image.png > | 01:18 | |
| Krey[m] | holySh@%! that scared me | 01:18 |
| pwr22 | Golem? | 01:25 |
| Krey[m] | The final form of campbell when goverment is not listening to him | 01:30 |
| Krey[m] | :p | 01:30 |
| Brainstorm | New from Reddit (test): CoronaVirus_2019_nCoV: Antivax antimask Covid deniers blocked the road at a vaccine center and harass the people waiting in line → https://is.gd/vgGpt1 | 01:33 |
| Brainstorm | Updates for Togo: +45 cases (now 13962), +1 deaths (now 130) since 19 hours ago | 01:39 |
| nixonix | that reddit video - how is it a scam? | 01:44 |
| nixonix | ppl are faking their symptoms and deaths, like those moon visits, that was it spielger who made those in studio? | 01:45 |
| nixonix | https://twitter.com/ashwil13/status/1407509728083779592 | 01:45 |
| nixonix | spielberg | 01:46 |
| nixonix | at least this guy puts out some effort: | 01:47 |
| nixonix | .title https://dryburgh.com/byram-bridle-coronavirus-vaccine-concerns/ | 01:47 |
| Brainstorm | nixonix: From dryburgh.com: "I would probably prefer to have natural immunity" — Viral Immunologist | 01:47 |
| Brainstorm | New from r/WorldNews: worldnews: Bangladesh, the most densely populated country in the world, reports highest ever Covid deaths on first day of strict lockdown with a 26% positivity rate → https://is.gd/GvbYfs | 01:54 |
| lavadonut | what % of viral immunologists would prefer to have natural immunity | 01:57 |
| lavadonut | "natural immunity" to viruses can have consequences way down the line | 02:01 |
| lavadonut | like chickenpox/shingles | 02:01 |
| nixonix | very low %. he is an anti mrna vaccine guy, whose arguments are used by anti-vaxers | 02:02 |
| nixonix | he has his own whole virus vaccine in development, which is possibly coming out in 2-4 years. just got over 200k for it | 02:03 |
| Brainstorm | Updates for India: +330 deaths (now 399459) since 17 hours ago | 02:04 |
| lavadonut | breaking news: non-mrna vaccine developer says mrna vaccines are bad | 02:05 |
| LjL | lavadonut, that's more than immunity (or less than immunity) though, that's the virus staying in the body forever | 02:10 |
| LjL | which... to be fair, is not quite ruled out for COVID, either | 02:10 |
| lavadonut | but it's a prerequisite for natural immunity | 02:10 |
| lavadonut | you don't get to say "i would rather have natural immunity, minus the inherent drawbacks of course" | 02:10 |
| LjL | yes, for those viruses | 02:11 |
| LjL | but there are also fortunately plenty of viruses that don't stay in the body forever | 02:11 |
| lavadonut | what about epstein-barr | 02:11 |
| LjL | yes, and herpes | 02:11 |
| LjL | without going to HIV which takes it to the next level | 02:12 |
| nixonix | heres some debunking for some of byram bridles claims: | 02:12 |
| nixonix | .title https://healthfeedback.org/claimreview/byram-bridles-claim-that-covid-19-vaccines-are-toxic-fails-to-account-for-key-differences-between-the-spike-protein-produced-during-infection-and-vaccination-misrepresents-studies/ | 02:12 |
| LjL | still doesn't mean all viruses do it, or even a majority | 02:12 |
| Brainstorm | nixonix: From healthfeedback.org: Byram Bridle’s claim that COVID-19 vaccines are toxic fails to account for key differences between the spike protein produced during infection and vaccination, misrepresents studies - Health Feedback | 02:12 |
| lavadonut | well i'll be taking my moderna vaccine all the way to the bank | 02:12 |
| nixonix | .title https://factcheck.afp.com/posts-misrepresent-us-study-dangers-coronavirus-spike-protein | 02:17 |
| Brainstorm | nixonix: From factcheck.afp.com: Posts misrepresent US study on dangers of coronavirus spike protein | Fact Check | 02:17 |
| nixonix | also i think he has claimed spike protein of mrna vaccines (but not his own vaccine???) would cross the blood-brain barrier, which happened in a mouse study | 02:19 |
| nixonix | it did happen, but not when they used mice with humanized blood-brain barrier | 02:19 |
| nixonix | higher s1 concentrations than whole spikes in SIMOA assay, after vaccination, are likely from cells that immune cells destroyed, which then release broken or partial s proteins to plasma | 02:22 |
| nixonix | and apparently s1 can also come from cells surface when enzymes recycle cells surface proteins like they normally do | 02:25 |
| joerg | are there any published calculations for Delta, similar to those about B1.1.7 https://www.sueddeutsche.de/wissen/coronavirus-mutante-b117-daten-1.5197700 back in january/february? | 02:27 |
| nixonix | what kind of calculations? | 02:29 |
| Brainstorm | Updates for Guatemala: +2855 cases (now 296438), +67 deaths (now 9282) since 22 hours ago — France: +17 deaths (now 111145) since 23 hours ago — Netherlands: +529 cases (now 1.7 million) since 23 hours ago — Canada: +460 cases (now 1.4 million) since 23 hours ago | 02:29 |
| joerg | the kind that generates diagrams/plots/forecasts like those in that article | 02:32 |
| LjL | joerg, for the UK, https://covid19.sanger.ac.uk/lineages/raw is good, they try to normalize things to resemble an unbiased sample | 02:32 |
| nixonix | oh, i had a look without js on, so i didnt see pics | 02:32 |
| LjL | for other countries, you may want to get the de-facto grapher going :P | 02:32 |
| joerg | answering the question if we are on a good path still or already on the beginning of next wave | 02:33 |
| LjL | de-facto said by his calculations, Delta should become prevalent in Germany by July 4 | 02:33 |
| nixonix | they have estimated the share of indian variant to double in every 2 weeks or so, when the dominating variant is 1.1.7 | 02:33 |
| LjL | so, just about now | 02:33 |
| joerg | >>Delta should become prevalent in Germany by July 4<< sounds about right, however aiui what really matters is not when it becomes prevalent but if the total number of Delta-cases is rising or going down | 02:35 |
| LjL | i think another wave is unavoidable. but whether it will have a considerable amount of deaths, so far the UK seems to indicate maybe not | 02:35 |
| LjL | well, it's definitely rising for now! | 02:35 |
| nixonix | until its close to 50%. as its roughly a sigmoid curve limited to 100%... | 02:35 |
| LjL | although Sanger seems to indicate it's been declining for a bit now in the UK | 02:35 |
| nixonix | but there were differencies in spreading of b.1.1.7 between countries. maybe some countries succeeded to limit importing it and then tracked down the clusters more efficiently. so it can be slowed down | 02:37 |
| nixonix | like denmark and norway are trying hard to do | 02:37 |
| LjL | we still have more deaths than the UK despite having had far fewer cases for quite a while now http://offloop.net/covid19/?default=United%20Kingdom;Italy&byPopulation=yes&cumulative=no&smooth=yes | 02:38 |
| nixonix | maybe in some groups other less fit variants can gain. then are those with more immune evasion abilities vs vaccinated etc | 02:38 |
| LjL | not sure if that tells you that Delta in the UK isn't able to cause many deaths, or just that Italians keep dying more easily because we kinda always did during COVID ;( | 02:38 |
| joerg | for B1.1.7 iirc the "goal" was to reach R_t<0.7 to compensate for later impact of the new variant. We reached R_t=9.6 4 weeks and a little bit less that 2 weeks ago, we are at ~ 0.85 now. I just wonder if that might suffice or not | 02:38 |
| nixonix | uk official death numbers miss a lot, even ONS had a lot higher numbers, and they missed too compared to excess deaths. spring 2020, not sure how it is now | 02:39 |
| joerg | R_t=0.6 even | 02:39 |
| LjL | joerg, well, for that it may still be useful to know that after July 4 it will be prevalent. because that means after that time, if the R goes up, Delta is going up, if the R goes down, Delta is going down | 02:39 |
| LjL | i mean, once it's the prevalent variant in a given country, it's dominating the R | 02:40 |
| joerg | sort of, yes | 02:40 |
| joerg | so us being at 0.85 now ( http://reisenweber.net/et_al/covid/covid19_statistics.htm ) isn't all too bad | 02:41 |
| nixonix | EU curve has started to go up a bit. too bad theres no combined EU curves for shares of positive tests | 02:43 |
| LjL | i don't know, maybe not, but it looks like a noisy graph. maybe it would be wise to wait like a week, at least, after july 4 (supposing that is the correct day) to see what's happening | 02:43 |
| nixonix | because it seems they are testing less. and that information owid gets isnt very recent | 02:43 |
| LjL | nixonix, not even sure if that would be useful given the varying testing strategies. we have separate curves in Italy for PCR and rapid tests, and they look very different | 02:44 |
| nixonix | you need to check both share of positive test, and tests made per 1000 | 02:44 |
| nixonix | rapid tests there, i assume they are confirmed with PCR? | 02:45 |
| nixonix | so you could just use those PCR numbers, both share of positives and tests made | 02:45 |
| LjL | nixonix, what about Covidly? it doesn't have a *graph* unifying the tests and cases for the EU, but it does have testing data | 02:45 |
| Brainstorm | New from Science Daily: COVID-19 test offers solution for population-wide testing, scientists say: Researchers report real-world results on SwabSeq, a high-throughput testing platform that uses sequencing to test thousands of samples at a time to detect COVID-19. They were able to perform more than 80,000 tests in less than two months, with the test [... want %more?] → https://is.gd/k5doWF | 02:45 |
| LjL | nixonix, i suppose positive ones are confirmed by PCR, but i'm just saying that different testing scenarios look different | 02:47 |
| joerg | if our politicians *again* just watch the numbers going up without immediately adapting measures to compensate early, I promise I convert to a militant corona-measures-fighter | 02:48 |
| nixonix | yeah, but if you want to see, like if spain is really stable or not, if their cases curve is stable, checking those test curves might tell the truth. unless they havent sent data recently... | 02:48 |
| nixonix | or released | 02:49 |
| nixonix | i dont find that type of information from covidly. theres cases to test ratio, but i think its total for the whole epidemic | 02:51 |
| LjL | hmm bummer, the Covidly JSON doesn't seem to have testing, even though they have testing in the graphs | 02:51 |
| LjL | nixonix, well there's tests, and there's cases, for each country | 02:51 |
| nixonix | with dates? so you could get that info by day and do your own curves? | 02:52 |
| nixonix | by date | 02:52 |
| LjL | nixonix, by date yes, on the graph, go to like https://covidly.com/graph?country=Finland&state= and click the "Tests" checkbox | 02:53 |
| LjL | but again if it's not in the JSON it would have to be tediously gotten manually | 02:53 |
| LjL | the JSON is at https://covidly.com/history if you can look better than me | 02:53 |
| LjL | that's not a public API so try not to do anything too boldly noticeable :P | 02:54 |
| LjL | in the totals in the json, i see vaccinations, which they added "recently" (obviously it wasn't there in 2020...) but i don't see any number corresponding to the tests | 02:54 |
| LjL | and "history" has the same 0 1 2 3 4 numbers | 02:55 |
| nixonix | ah, i was clicking tab for tests. but not positives, just for tests made? | 02:56 |
| LjL | nixonix, well "positives" is cases...? | 02:57 |
| LjL | but i'm surprised it's not in the json because i thought the json is what the site itself was using to get data from (it gets loaded when you load a page) | 02:57 |
| nixonix | yeah.. not necessarily, but roughly. so it could be sued | 02:57 |
| nixonix | used | 02:57 |
| joerg | thanks! | 02:59 |
| joerg | o/ | 02:59 |
| LjL | joerg won't stay joined 'cause i "threatened" him by opping up once | 03:01 |
| LjL | bit of a low bar for leaving a channel i'd say | 03:01 |
| LjL | in fact i'm opped up right now! hope i'm not threatening anyone :P | 03:02 |
| jacklsw | intimidating :D | 03:03 |
| jacklsw | woops no more | 03:03 |
| nixonix | bye | 03:06 |
| Brainstorm | Updates for Cyprus: +473 cases (now 76333) since 22 hours ago | 03:06 |
| Krey[m] | <LjL "joerg won't stay joined 'cause i"> fufufu stop bullying people | 03:08 |
| Brainstorm | Updates for Germany: +1501 cases (now 3.7 million), +227 deaths (now 91530) since 14 hours ago | 03:31 |
| Brainstorm | New from NPR: Johnson & Johnson's COVID Vaccine Is Effective Against The Delta Variant, Studies Find: The results follow similar announcements about the Pfizer and Moderna vaccines, in the fight against the fast-spreading delta strain. → https://is.gd/Zz7PQ1 | 03:47 |
| LjL | is it very weird I'm almost looking forward to the probable side effects of my second Pfizer dose? | 04:04 |
| LjL | i usually get very bummed when i'm feeling even mildly ill | 04:04 |
| lavadonut | that is weird | 04:05 |
| lavadonut | 2nd dose moderna side effects were awful | 04:05 |
| lavadonut | felt like the actual flu | 04:06 |
| LjL | well, maybe i'll change my mind once i actually feel them | 04:07 |
| LjL | i felt nothing with the first dose except sore arm | 04:07 |
| lavadonut | my first dose was also barely anything | 04:08 |
| lavadonut | i had the joint pain... hope that isn't a sign of arthritis in my future :') | 04:09 |
| Brainstorm | Updates for Isle of Man: +7 cases (now 1620) since a day ago | 04:33 |
| nana | LjL: you never got the 2nd dose? | 04:44 |
| LjL | nana, "never" is a strong word, i'm due to get it in 6 days | 04:45 |
| LjL | which is lucky because if i had gotten AZ that'd have been a much longer wait | 04:46 |
| LjL | lavadonut, why do you think it could be a sign of arthritis? | 04:46 |
| LjL | i always have join pain when i'm feeling bleh :P | 04:46 |
| nana | seems like your 1st was a long time ago | 04:47 |
| LjL | nah | 04:47 |
| LjL | 5 June | 04:47 |
| nana | got mine @2 weeks | 04:47 |
| LjL | nana, that's a bit too close... | 04:48 |
| LjL | minimum should be 21 days apart | 04:48 |
| nana | actually maybe it was 3 nvm | 04:48 |
| LjL | well yeah it can be 3 here but up to 48 days is acceptable, so mine was around a month apart, which is fine | 04:48 |
| nana | vaccines are poorly understood by the general public it seems | 04:51 |
| LjL | the general public is a varied lot | 04:52 |
| LjL | what do you think is particularly misunderstood? | 04:52 |
| nana | instead of lotteries and free snacks, if there was some education | 04:52 |
| lavadonut | maybe you have arthritis | 04:57 |
| Brainstorm | New from The Indian Express: World: J&J’s says its single-shot Covid-19 vaccine shows strong activity against Delta variant → https://is.gd/Hp79l7 | 04:59 |
| Brainstorm | Updates for Liechtenstein: +3 cases (now 3039) since a day ago | 05:11 |
| Brainstorm | New from The Indian Express: World: Novavax says Taiwan has opted to get firm’s Covid vaccine via COVAX → https://is.gd/9jQE68 | 05:19 |
| Brainstorm | Updates for Thailand: +6087 cases (now 270921), +61 deaths (now 2141) since 23 hours ago — Mexico: +8016 cases (now 2.5 million), +201 deaths (now 233248) since 23 hours ago — Bahamas: +149 cases (now 12735) since a day ago — Australia: +42 cases (now 30684) since 23 hours ago | 05:36 |
| Kapten_Krayt0m_ | Does the vax really make people magnetic? | 05:47 |
| Brainstorm | Updates for South Korea: +826 cases (now 158549), +3 deaths (now 2024) since 23 hours ago | 06:00 |
| Brainstorm | New from The Indian Express (Health): Life-style: Sonam Kapoor recommends these DIY face masks for healthy, glowing skin → https://is.gd/GRsdjg | 06:33 |
| Brainstorm | Updates for Liberia: +211 cases (now 4304), +1 deaths (now 129) since a day ago — Belgium: +754 cases (now 1.1 million), +7 deaths (now 25180) since 22 hours ago | 06:38 |
| Brainstorm | New from The Indian Express: World: Sydney braces for rise in COVID-19 cases as Delta outbreak worsens → https://is.gd/FppWvc | 07:05 |
| Brainstorm | Updates for England, United Kingdom: +22515 cases (now 4.2 million), +16 deaths (now 112710) since a day ago — Unknown, Peru: +5489 cases (now 23948), +356 deaths (now 1781) since a day ago — Scotland, United Kingdom: +4234 cases (now 285456), +6 deaths (now 7722) since a day ago — Saint Petersburg, Russia: +1612 cases (now 471264), +115 deaths (now 16461) since a day ago | 07:40 |
| Brainstorm | New from The Indian Express: World: US Military and veterans struggle with vaccination rates in their ranks → https://is.gd/iJDHK4 | 08:07 |
| Brainstorm | Updates for India: +46617 cases (now 30.5 million), +1101 deaths (now 400312) since 15 hours ago | 08:36 |
| Brainstorm | New from Reddit (test): COVID19: Scientists quit journal board, protesting ‘grossly irresponsible’ study claiming COVID-19 vaccines kill → https://is.gd/39JDHc | 08:59 |
| Krey[m] | <LjL "is it very weird I'm almost look"> did you told them to aspirate? | 08:59 |
| Brainstorm | New from r/Coronavirus: Daily Discussion Thread | July 02, 2021: Please refer to our Wiki for more information on COVID-19 and our sub. You can find answers to frequently asked questions in our FAQ , where there is valuable information such as our: → https://is.gd/BDK9we | 09:10 |
| Brainstorm | Updates for British Virgin Islands: +42 cases (now 392) since 23 hours ago | 09:38 |
| Brainstorm | New from Reddit (test): Covid2019: WHO tells Cuba to publish its COVID-19 vaccine data and to seek approval for COVAX → https://is.gd/I1VMrk | 10:01 |
| Brainstorm | Updates for Fiji: +404 cases (now 5253), +1 deaths (now 25) since 23 hours ago | 10:09 |
| Brainstorm | New from WHO Euro: Largest disruption to schooling in history due to COVID-19 measures must not rob children of their education and development: Schools should remain open for as long as possible with adequate public health and social measures in place, and governments should use the summer months to implement measures that protect in-person schooling [... want %more?] → https://is.gd/QOwQCL | 10:21 |
| Brainstorm | Updates for Lesotho: +128 cases (now 11544) since 23 hours ago | 10:34 |
| Brainstorm | New from StatNews: Opinion: The health care workforce is understaffed for life after Covid-19: As the U.S. gradually unburies itself from the Covid-19 pandemic, some people have been sounding the alarm about looming shortages of physicians and nurses. They should be equally worried about… → https://is.gd/VZYRuA | 10:53 |
| Krey[m] | hmm | 11:06 |
| Krey[m] | poked myself 4 times my hands are bloody and that hugging SH!^@^ is still not measuring | 11:06 |
| Krey[m] | then i relized that the blood has to be from the bottom of the test strip | 11:06 |
| Krey[m] | got glucometer | 11:06 |
| Krey[m] | -.-" | 11:06 |
| Brainstorm | New from The Indian Express (Health): Health: How can you protect yourself from non-Covid illnesses in the monsoon? → https://is.gd/y8GaFR | 11:24 |
| Brainstorm | New from The Indian Express: World: Japan could face vaccine crunch as it nears Olympics start → https://indianexpress.com/article/world/tokyo-olympics-2020-covid-vaccine-crunch-7385916/ | 11:36 |
| Krey[m] | DW reports "Delta Plus" variant https://youtu.be/AFoFsLxhdi8 | 11:46 |
| Krey[m] | Epsilon Variant? | 11:47 |
| Krey[m] | LjL: ^ | 11:47 |
| * Krey[m] is getting more suspicious that someone in india is engineering these | 11:50 | |
| Krey[m] | %cases india | 11:51 |
| Brainstorm | Krey[m]: In India, there have been 30.5 million confirmed cases (2.2% of the population) and 400312 deaths (1.3% of cases) as of 3 hours ago. 414.3 million tests were performed (7.4% positive). Fatality can be broadly expected to lie between 0.4% (assuming prevalence as in tests) and less than 1.3% (considering only deaths and recoveries). See https://offloop.net/covid19/?default=India for time series data. | 11:51 |
| Krey[m] | smh did the bridge broke again | 11:51 |
| genera | i v been told its intentional. but arent you [m] ? | 12:01 |
| kreyren | LjL, i assume that your matrix bridge is hugged again | 12:02 |
| kreyren | DW reports "Delta Plus" variant https://youtu.be/AFoFsLxhdi8 | 12:02 |
| * kreyren goes back to his safe place on matrix | 12:03 | |
| Brainstorm | New from ScienceNews: What experts know so far about the delta variant: The variant, which first emerged in India, is outcompeting other highly transmissible forms of the coronavirus as it spreads around the world. → https://is.gd/hqHv8c | 12:08 |
| rpifan | dw produces more english content then german | 12:20 |
| rpifan | thats a bit shit | 12:20 |
| Brainstorm | New from BMJ: Covid-19: Millions could be offered booster vaccinations from September: Covid-19 booster vaccinations should be offered in England from September 2021, the Joint Committee on Vaccination and Immunisation has advised. But some experts have questioned the necessity and the... → https://is.gd/Niadbw | 12:29 |
| Brainstorm | Updates for Germany: +1504 cases (now 3.7 million) since 23 hours ago | 12:32 |
| Brainstorm | New from r/WorldNews: worldnews: Delta variant sweeps Asia, prompting curbs as vaccination remains tepid → https://is.gd/CMtFML | 12:50 |
| zutt | %cases finland | 12:54 |
| Brainstorm | zutt: In Finland, there have been 95964 confirmed cases (1.7% of the population) and 973 deaths (1.0% of cases) as of 21 hours ago. 5.4 million tests were performed (1.8% positive). Fatality can be broadly expected to lie between 1.0% (assuming prevalence as in tests) and less than 2.1% (considering only deaths and recoveries). See https://offloop.net/covid19/?default=Finland for time series data. | 12:54 |
| Brainstorm | New from ECDC: Data on COVID-19 vaccination in the EU/EEA: The downloadable data files contain information on COVID-19 vaccination in the EU/EEA. The data are presented in the Vaccine Tracker and collected through The European Surveillance System (TESSy). → https://is.gd/tmWhQm | 13:11 |
| de-facto | .title https://arxiv.org/abs/2106.11129 | 13:32 |
| Brainstorm | de-facto: From arxiv.org: [2106.11129] The Effectiveness of Strategies to Contain SARS-CoV-2: Testing, Vaccinations, and NPIs | 13:32 |
| Brainstorm | Updates for Indonesia: +25830 cases (now 2.2 million), +539 deaths (now 59534) since a day ago | 13:34 |
| pwr22 | Just read that apparently my astrazeneca vaccines don't count in the EU passport scheme | 13:38 |
| pwr22 | Not that I'm really planning to travel around but as far as I'm aware the data in the UK is indicating it works well enough to keep problems from even the delta variant at bay so the EU can **** right off with it's political bull**** | 13:39 |
| pwr22 | No offence meant to anyone in the EU, I mean the government | 13:40 |
| pwr22 | Seems like it is if it comes from India, not sure how to verify my batches are legit | 13:42 |
| de-facto | Interestingly rapid-ag-tests are as efficient as seasonality (~40%) in reducing reproduction | 13:46 |
| de-facto | thats a lot | 13:46 |
| de-facto | "The objective of this study is to explain the quantitative effects of these policies on determining the course of the pandemic, allowing for factors like seasonality or virus strains with different transmission profiles. To do so, the study develops an agent-based simulation model, which is estimated using data for the second and the third wave of the CoViD-19 pandemic in Germany." | 13:47 |
| de-facto | "The paper finds that during a period where vaccination rates rose from 5% to 40%, large-scale rapid testing had the largest effect on reducing infection numbers. Frequent large-scale rapid testing should remain part of strategies to contain CoViD-19; it can substitute for many non-pharmaceutical interventions that come at a much larger cost to individuals, society, and the economy." | 13:48 |
| Brainstorm | New from The Indian Express (Health): Art and Culture: Shillong Chamber Choir, Parikrama perform to raise funds for Covid-affected children → https://is.gd/Rspvmw | 14:04 |
| Brainstorm | New from BBC Health: (news): Covid: Britons reassured over India-made Covishield jabs and EU travel → https://is.gd/xkMpbd | 14:14 |
| de-facto | I think bi-weekly tests at both, schools and working places should be made mandatory by law. | 14:20 |
| de-facto | I am against making vaccinations mandatory, but i am for making tests on regular bi-weekly schedule mandatory without any exceptions, this would make a huge difference if enforced on large scale | 14:21 |
| de-facto | somehow also testing in households should be enforced, not sure how though | 14:23 |
| Brainstorm | Updates for Iran: +13836 cases (now 3.2 million), +127 deaths (now 84516) since 22 hours ago — Nepal: +1391 cases (now 642053), +34 deaths (now 9179) since 22 hours ago | 14:36 |
| dTal | de-facto, nothing has been enforced at all this pandemic | 14:55 |
| dTal | cept maybe in China | 14:56 |
| de-facto | NPIs, lockdowns, testing for participation, quarantine | 15:00 |
| de-facto | i think its extremely important to somehow achieve widespread and regular testing in all areas where citizens spend their time, be it school, work or household | 15:01 |
| de-facto | there is no health risk emerging from that at all, and now with tests available for under 1€ they should be used | 15:02 |
| de-facto | it really makes a big difference | 15:02 |
| de-facto | and since there will be some that oppose to that but still demand participation in society i think this should be made mandatory | 15:04 |
| de-facto | it literally takes a few minutes, i have done that many times already | 15:04 |
| de-facto | worst thing that happened to me from doing rapid tests was that it tickled my nose so i had to sneeze | 15:06 |
| de-facto | but there also are those tests where people just user their saliva (spit test), those are absolutely non-invasive and even smallest kids can easily do that without *any* possible harm | 15:07 |
| * martini_man[m] uploaded an image: (322KiB) < https://libera.ems.host/_matrix/media/r0/download/nerdsin.space/a3c2488c85e768b17cad4ca39199eafe03c4d8fb/image.png > | 15:16 | |
| Brainstorm | New from Francois Balloux: @BallouxFrancois: I would likely reach the same conclusion if my primary source of information about covid were @DrEricDing. → https://is.gd/gdLgD2 | 15:18 |
| Brainstorm | Updates for Switzerland: +158 cases (now 703334) since 23 hours ago — Germany: +1494 cases (now 3.7 million) since 23 hours ago | 15:38 |
| Brainstorm | Updates for Saudi Arabia: +2844 cases (now 490464), +29 deaths (now 7848) since 20 hours ago — Bangladesh: +8483 cases (now 930042), +132 deaths (now 14778) since a day ago — Canada: +8 deaths (now 26295) since 18 hours ago | 16:03 |
| Brainstorm | New from In The Pipeline: The Underside of the Aducanumab Approval: I would like to recommend this piece at Stat about the details of the Biogen aducanumab approval. It’s behind the paywall, but it’s a deeply reported piece from Adam Feuerstein, Matthew Herper, and Damian Garde about how in 2019 Biogen launched an effort to get their apparently [... want %more?] → https://is.gd/o2Qa3L | 16:43 |
| Brainstorm | New from Francois Balloux: @chrischirp: RT by @BallouxFrancois: Israel surely can't just let 1 million Pfizer vaccines go to waste... with a 3 week dose interval you could still vaccinate 500k people by end JulyIf the will was there, surely they could be donated to its neighbours or further afield. This is terrible. [... want %more?] → https://is.gd/UsK4g7 | 16:54 |
| Brainstorm | New from Retraction Watch: Journal retracts paper claiming two deaths from COVID-19 vaccination for every three prevented cases: Just days after adding an expression of concern to a paper published last week claiming that two people died from COVID-19 vaccinations for every three cases the vaccines prevented, the journal Vaccines has retracted the [... want %more?] → https://is.gd/keEfJZ | 17:15 |
| Brainstorm | New from EMA: What's new: News: Increased manufacturing capacity for COVID-19 Vaccine Janssen → https://is.gd/Z9XLWQ | 17:26 |
| Brainstorm | New from Medical Xpress: COVID pandemic on the rise again: The pandemic picked up speed again this week in all regions of the world except Latin America. → https://is.gd/Klf0CD | 17:36 |
| Brainstorm | New from LitCovid: (news): Infection control, prophylactic antibiotics, and testing for SARS-CoV-2 and PPE on German intensive care units: results from a national mixed methods survey. → https://is.gd/BxmD9Y | 17:47 |
| Brainstorm | Updates for United Kingdom: +30422 cases (now 4.9 million) since 22 hours ago | 18:07 |
| LjL | genera, it's not quite intentional, the Matrix bridge malfunctioning, what's intentional is a "privacy feature" that tends to break it more often than it otherwise would, but there are generalized problems with it anyway. Krey probably couldn't see what you were typing back to him | 18:10 |
| LjL | J%J did a serum neutralization study on the Indian variant, which they say did better than on the South African variant, and according to https://www.nejm.org/doi/full/10.1056/NEJMoa2101544 the South African variant has 81.7% efficacy against severe disease as opposed to 85.4% for the original variant so that would be pretty close. but still the one about the Indian variant is not a study on what happens to actual people | 18:18 |
| -RSSBot[LjLmatrix- Recent Commits to links:master: Give J&J vaccine its separate section ( https://github.com/ljl-covid/links/commit/e1ef65da9af9da89c8dafb387cd05dcf7fff718e ) | 18:23 | |
| Brainstorm | New from https://covid19.specops.network : ljl-covid: Give J&J vaccine its separate section → https://is.gd/hbT1Xe | 18:29 |
| genera | in other news, is the bridge your bridge or the general matrix-libera bridge? | 18:31 |
| LjL | general | 18:31 |
| LjL | i cannot provide a bridge that joins each user as a separate user, i'd get k-lined i no time | 18:32 |
| -RSSBot[LjLmatrix- Recent Commits to links:master: Add J&J/Janssen press release on Delta serum study and durability ( https://github.com/ljl-covid/links/commit/c1e73a1f046b9b32c0b4370f5c5d6b52fdc69ba8 ) | 18:33 | |
| Brainstorm | New from https://covid19.specops.network : Add J&J/Janssen press release on Delta serum study and durability: Courtesy imaginary. I need to find the actual bioXriv preprints mentioned by not linked to → https://is.gd/T8siJt | 18:40 |
| -RSSBot[LjLmatrix- Recent Commits to links:master: Move misplaced J&J press release ( https://github.com/ljl-covid/links/commit/5fad8d29d352ecffec408b87b69d50dd030d73d4 ) | 18:43 | |
| -RSSBot[LjLmatrix- Recent Commits to links:master: Add "durability of response" part of J&J press release ( https://github.com/ljl-covid/links/commit/96d94cbd6ace20f752b8fefeb5f1a63353b418b7 ) | 18:48 | |
| -RSSBot[LjLmatrix- Recent Commits to links:master: Add J&J preprint about Delta neutralization ( https://github.com/ljl-covid/links/commit/d08490eaef206ce00bdb8e73fca2ae98b53d8e34 ) | 18:48 | |
| Brainstorm | New from https://covid19.specops.network : ljl-covid: Add J&J preprint about Delta neutralization → https://is.gd/iNx0aC | 18:51 |
| pwr22 | LjL: what's up with those funky permission changes? | 19:24 |
| LjL-Matrix | Peter: oh wow. I just restarted my bot a few times to solve an issue... but since it's voiced in the channel, every time it rejoins the bridge gives it the closest Matrix equivalent to voice, which is level 1 | 19:27 |
| LjL-Matrix | I've solved the issue so I likely won't be restarting it anymore for a while, if that helps ;P | 19:28 |
| Brainstorm | Updates for Italy: +794 cases (now 4.3 million), +28 deaths (now 127615) since a day ago | 19:37 |
| pwr22 | Sure, I don't mind it anyhow just confused by it | 19:38 |
| Brainstorm | New from CIDRAP: News Scan for Jul 02, 2021: COVID-19 in sickle cell disease COVID risk for emergency responders Cyclospora prevention Polio in Nigeria Maine Powassan virus case → https://is.gd/hzZti9 | 19:55 |
| de-facto | i put my bots behind ZNC, so i even can connect multiple bots under one nick :D | 20:17 |
| LjL | de-facto, mine is under ZNC too, the problem was with ZNC :P | 20:20 |
| LjL | and it's three bots :P | 20:20 |
| LjL | speaking of | 20:20 |
| LjL | %fdroid Covid Check | 20:20 |
| Brainstorm | LjL: no application with that name was found! | 20:20 |
| LjL | %fdroid Covid certificate | 20:21 |
| Brainstorm | LjL, COVID Certificate Check 1.2.0 (ch.admin.bag.covidcertificate.wallet) in https://f-droid.org/repo: Check COVID certificates - updated 2021-07-02, see https://github.com/admin-ch/CovidCertificate-App-Android/releases | 20:21 |
| LjL | this is a couple of Swiss apps, they tell me my certificate is invalid due to invalid signature, but maybe they just need to update the signatures tomorrow | 20:21 |
| LjL | anyway if you're using F-Droid it's a neat enough app to keep digital copies of your certificates, if you don't want to use other countries' apps from Play | 20:21 |
| LjL | (not the "Check" one but the other one that lets you store one or multiple certificates) | 20:22 |
| LjL | right now there is a bit of a mess with these apps in F-Droid, one is really the other one, there's a bug filed at https://gitlab.com/fdroid/fdroidserver/-/merge_requests/981 | 20:22 |
| LjL | but anyway they work, you just have to download the "Check" app if you want the other one :P | 20:23 |
| LjL | the only Swiss-specific thing it seems to do is check against the Swiss signature server (?) and tell you whether the certificate is valid for Switzerland (mine isn't, for example, because i got just one dose) | 20:23 |
| LjL | but it doesn't matter if you are just using it to show your certificate to someone *else* checking it with their own app | 20:23 |
| showmethewave | CDC does not recommend aspiration during intramuscular application of vaccines [18]. However, in the case of adenovirus-based vaccines, aspiration prior to injection could offer a simple preventive measure against TTS | 20:33 |
| de-facto | hey n :) | 20:34 |
| showmethewave | our data provide first experimental support for the potential sequence of events that could lead to TTS in some patients: Thrombocytopenia might be a result of accidental intravenous vaccine injection with ensuing platelet-adenovirus aggregation, which in turn triggers platelet activation and subsequent splenic clearance | 20:34 |
| showmethewave | luckily i just recommended asking ASS for a relative who just got her jab | 20:35 |
| showmethewave | pfizer though, but who knows maybe theres some risk too | 20:36 |
| showmethewave | https://www.biorxiv.org/content/10.1101/2021.06.29.450356v1.full | 20:36 |
| showmethewave | .title | 20:36 |
| Brainstorm | showmethewave: From www.biorxiv.org: Thrombocytopenia and splenic platelet directed immune responses after intravenous ChAdOx1 nCov-19 administration | bioRxiv | 20:36 |
| showmethewave | did EU just reached its low point for cases this summer? signs that its going up now | 20:38 |
| showmethewave | we had the low point around 15th june because early removing of bar, event and travelling restrictions | 20:38 |
| LjL | and also likely because Delta is now rising, and possibly because of that paper that says seasonally, July 1 is the low point anyway | 20:39 |
| showmethewave | btw, how was it the median time from infection to hospital admission? i remember around 9-10 days, but was it from infection or testing positive? | 20:39 |
| LjL | so yeah there are a few reasons why they may be going up now | 20:39 |
| showmethewave | might be different with indian variant, tho | 20:39 |
| Brainstorm | Updates for South Africa: +24270 cases (now 2.0 million), +303 deaths (now 61332) since 23 hours ago — Morocco: +844 cases (now 532994), +9 deaths (now 9307) since 23 hours ago — Spain: +12563 cases (now 3.8 million), +28 deaths (now 80911) since 23 hours ago — Germany: +1368 cases (now 3.7 million) since 22 hours ago | 20:39 |
| de-facto | R-value in Germany in the rise, soon to pass 1 i guess | 20:39 |
| LjL | yeah i remember the same, but i don't remember details | 20:39 |
| LjL | perhaps from symptoms | 20:40 |
| showmethewave | if R was clearly under 1 because of summer and all, if the restrictions, travelling and ppl behavior remains the same, it takes around 40-50% share to get it over 1 | 20:40 |
| showmethewave | then theres around week delay from infection to testing positive, and reporting it. so its already higher probably when cases start to go up | 20:41 |
| nixonix | those official R's use some formula which arent necessarily the same than whats really happening. like using hospital numbers etc - and young ppl dont show up in those usually | 20:42 |
| de-facto | .title https://www.epicentro.iss.it/en/coronavirus/sars-cov-2-analysis-of-deaths | 20:42 |
| Brainstorm | de-facto: From www.epicentro.iss.it: Characteristics of COVID-19 patients dying in Italy | 20:42 |
| nixonix | and it always starts with travelling, which is young dominant but older too (young go more bars etc), then community spreading is among 18-35 mostly at first | 20:43 |
| LjL | uhm the EU as a whole is going *sharply* up, much more than Germany | 20:43 |
| LjL | http://offloop.net/covid19/?default=EU;Germany&cumulative=no&smooth=yes | 20:43 |
| LjL | do you know which country(es) are responsible? | 20:43 |
| pwr22 | Cases and / or deaths? | 20:43 |
| de-facto | nixonix its the quotient of two rolling averages delayed by serial time defined at ts = 4d, other may use ts=5.2d | 20:43 |
| nixonix | like the last summer, it took 4-8 weeks in europe after cases started to rise fast, that to show up in deaths curve | 20:43 |
| nixonix | because those young first infect middle age parents and other older ppl, who then infect their old parents | 20:44 |
| de-facto | LjL, wait for it, in Germany R(B.1.617.2) ~ 1.3 too, hence doubling each 11d | 20:44 |
| pwr22 | Lol, the uk has more cases per day than the whole of the EU 🤦♂️ | 20:45 |
| de-facto | its just about to become visible | 20:45 |
| nixonix | anyways, it looks like reduced testing lately, so look closely the positive share rising for signs | 20:45 |
| de-facto | unfortunately we are no exception, just our stupid politicians did not realize yet | 20:45 |
| LjL | de-facto, it's already kinda visible in offloop although offloop is a bit affected by its averaging towards the end | 20:45 |
| nixonix | if they release them | 20:45 |
| LjL | pwr22, yeah... but low deaths... i don't know what to think of it | 20:45 |
| nixonix | eu curve for deaths was rising a bit. might be just variance | 20:46 |
| de-facto | it will rise again, of course, vaccinations just change the ratio between cases and fatalities, but the factor is not zero | 20:46 |
| LjL | oh Spain is definitely going up | 20:47 |
| de-facto | dang why is EU curve rising *that* sharply | 20:47 |
| nixonix | im most worried about unvaccinated kids getting permanent damage, brain, telomeres and who knows what else | 20:47 |
| nixonix | those adults that dont want vaccine - their own fault | 20:47 |
| de-facto | its sharper than any country i have seen yet | 20:47 |
| LjL | de-facto, check Spain | 20:47 |
| LjL | although Spain looks much more dramatic with smoothing *on* than off | 20:47 |
| de-facto | yes dang Spain got a super steep rise there | 20:48 |
| de-facto | did they had some soccer matches superspreads or such? | 20:48 |
| nixonix | put them in half logaritmic scale. sure small rising could be just variance, we'll now in about a week | 20:48 |
| nixonix | +h | 20:49 |
| de-facto | dangit all the EU countries got that kink there, on logscale | 20:49 |
| de-facto | this is Delta | 20:49 |
| nixonix | i read also belgian soccer fans imported indian variant from russia | 20:49 |
| nixonix | but prob nobody else as much as us | 20:49 |
| de-facto | just exactly how i predicted, begin to mid of july delta will make incidence rise again | 20:50 |
| de-facto | germany just is a bit behind | 20:50 |
| de-facto | i think we need NPIs immediately right NOW | 20:51 |
| de-facto | because later they will be exponentially more expensive | 20:51 |
| de-facto | R~1.3 is not tolerable at all | 20:51 |
| nixonix | couple weeks earlier than last summer, when its mostly from mid july in western europe. faster in balkan, because they were efficient with hard measures on spring 2020, had not much cases, lifted restrictions and forgot about the epidemic | 20:51 |
| nixonix | when it *was | 20:51 |
| nixonix | here because of stricter travelling restrictions last summer, had the rise starting by the end of july. now it was mid june | 20:52 |
| Arsanerit | How many deaths are caused by Euro 2020? | 20:52 |
| nixonix | happy go lucky | 20:52 |
| de-facto | EU got R~1-3 Spain even R~1.8 | 20:52 |
| de-facto | EU got R~1.3 Spain even R~1.8 | 20:52 |
| nixonix | 90 million? | 20:52 |
| nixonix | .title https://www.nbcboston.com/news/coronavirus/biogen-conference-in-boston-now-tied-to-more-than-300000-coronavirus-cases/2254941/ | 20:52 |
| Brainstorm | nixonix: From www.nbcboston.com: Biogen Conference in Boston Linked to More Than 300,000 COVID-19 Cases, Science Journal Study Suggests – NBC Boston | 20:52 |
| Arsanerit | nixonix: how would they tell some of those people wouldn't have gotten covid via another path otherwise? | 20:53 |
| nixonix | dudes, where can i see restrictions for all the possible european countries easily? bars, nighclubs, events etc, the high risk businesses (not interested in closed barbershops and stuff...) | 20:54 |
| Arsanerit | I think reopen.europa.eu only has quite limited information | 20:54 |
| Arsanerit | I don't think you'll find that info nixonix... in Germany such restrictions are per county (Landkreis) | 20:55 |
| nixonix | or tell me about your countries and those that you know about. bars open, early closure times or something still? evens allowed, outdoors, indoors? | 20:55 |
| de-facto | .title https://www.ecdc.europa.eu/en/cases-2019-ncov-eueea | 20:55 |
| Brainstorm | de-facto: From www.ecdc.europa.eu: COVID-19 situation update for the EU/EEA, as of 2 July 2021 | 20:55 |
| de-facto | .title https://arxiv.org/abs/2106.11129 <-- Arsanerit this is a really good modeling for Germany, worth a look | 20:56 |
| Brainstorm | de-facto: From arxiv.org: [2106.11129] The Effectiveness of Strategies to Contain SARS-CoV-2: Testing, Vaccinations, and NPIs | 20:56 |
| nixonix | we have outdoor events mostly allowed, i think not in metropolian area yet, but elsewhere. still limited client numbers for indoor gatherings, movies etc, and slightly limited hours for bars for highest prevalence regions | 20:56 |
| de-facto | it shows that rapid testing was just about as effective as seasonality (both ~40% R reduction) | 20:56 |
| nixonix | the problem is, they miss a lot, and ppl think they are rona free. those rapid tests | 20:57 |
| nixonix | they should be used only when cases are high imo. cdc thought the same | 20:57 |
| Arsanerit | de-facto: ok, so that should continue in any case | 20:58 |
| Arsanerit | I don't like the nose-drilling though :( | 20:58 |
| nixonix | when we never had them high, we havent used them. some regions used some rapid tests that eu bought (using our money) and pushed to us | 20:58 |
| Arsanerit | We have rapid tests at work. | 20:58 |
| de-facto | it makes a big difference | 20:59 |
| de-facto | i think i just will do it regularly 2x a week, each of them costs 80 cent here | 21:00 |
| nixonix | the indian variant has flu like symptoms for some people, so they have been thinking they have some common cold or allergic symptoms, and didnt go to test before they were traced down or symptoms got worse | 21:01 |
| nixonix | and been moving around in bars etc | 21:01 |
| nixonix | also an infectious disease doc claimed - and similar anecdotal on soccer forum - that many ppl have got symptoms and still negative pcr tests | 21:02 |
| de-facto | we really need much more strict NPIs, otherwise we need months long lockdowns soon | 21:02 |
| nixonix | and the indian variant would often show in tests later than symptoms | 21:02 |
| de-facto | now its still low incidence, hence the chance to control it early, it will me astronomically more cheap this way | 21:02 |
| nixonix | not sure if i believe | 21:02 |
| nixonix | travelling and bars, and indoor events ofc, are the key | 21:03 |
| nixonix | not much else is needed if those are tight | 21:03 |
| de-facto | i think many are irritated by the data because they dont take into account that comparing Alpha with Delta also includes comparing a mostly non-vaccinated population with one where most risk group are vaccinated (at least once) and that Delta now spreads in the young rather than in the elderly | 21:04 |
| Brainstorm | Updates for Canada: +19 deaths (now 26306) since 23 hours ago | 21:04 |
| de-facto | so if people say things like Delta is 6x less fatal than Alpha it just shows they are not able to take all the circumstances into account | 21:04 |
| de-facto | i am pretty sure Delta is more severe than Alpha when comparing the exact same cohorts | 21:05 |
| de-facto | id think about 1.5-2x | 21:05 |
| nixonix | yeah, it looks less severe because its mostly among 18-30 yo now, here at least | 21:05 |
| de-facto | yes but Alpha would have been even less severe in those groups | 21:05 |
| nixonix | uk estimates were indian was 2x more severe than uk kent variant. not sure if they have more recent info now | 21:06 |
| de-facto | sounds about accurate though | 21:06 |
| de-facto | wow RKI is using GitHUB now | 21:08 |
| de-facto | https://github.com/robert-koch-institut | 21:08 |
| de-facto | thats new | 21:09 |
| nixonix | .title https://www.eurekalert.org/pub_releases/2021-06/acop-crt062221.php | 21:09 |
| Brainstorm | nixonix: From www.eurekalert.org: Case reports thrombocytopenia with thrombosis following COVID-19 mRNA vaccine | EurekAlert! Science News | 21:09 |
| nixonix | .title https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8103126/ | 21:10 |
| Brainstorm | nixonix: From www.ncbi.nlm.nih.gov: No evidence of TTS risk with Pfizer/BioNTech's COVID-19 vaccine | 21:10 |
| nixonix | uk has free lateral flow test from pharmacy, you get a pack of 20 or something free every 2 weeks | 21:12 |
| nixonix | yet they have cases going up rapidly | 21:12 |
| genera | vom Wiegen wird die Sau nicht fett | 21:13 |
| nixonix | its the restrictions that count. you dont know what effect rapid tests do, when other measures are being done at the same time. without large study where all the possible NPI's are taken into account at the same time | 21:14 |
| nixonix | so its just speculation which one had effect, without above | 21:14 |
| nixonix | hopefully that 41 country study team does another one using the fall and winter data | 21:15 |
| genera | it still is a different time now that we have rapid tests for 89 cents | 21:15 |
| Krey[m] | Opinions on Delta plus variant ? | 21:17 |
| nixonix | also when people do it themself, they dont scrape behind the brain like it should be done. meaning way more false negatives | 21:17 |
| Brainstorm | New from r/WorldNews: worldnews: Brazil top prosecutor to investigate Bolsonaro over COVID-19 vaccine deal → https://is.gd/MJJNJz | 21:18 |
| nixonix | ppl have an exposure situtation or symptoms, so instead of going to proper PCR test they do that rapid test. it gives them a false negative, and they think its just a cold. ok, ill do another one in the evening, perhaps... | 21:21 |
| nixonix | so theres that same old efficiency vs effectiveness problem. it might be decent in a lab, but not among population and real life | 21:22 |
| de-facto | .title https://imgur.com/a/c9Vh3by https://i.imgur.com/wL2PzsA.png src: https://github.com/robert-koch-institut/SARS-CoV-2-Nowcasting_und_-R-Schaetzung/blob/main/Nowcast_R_aktuell.csv | 21:22 |
| Brainstorm | de-facto: From imgur.com: COVID Germany: Infections and Reproduction - Album on Imgur | 21:23 |
| de-facto | dangit look at the sharp rise in R-value at the tail | 21:23 |
| de-facto | pretty sure we are close to minimum (R~1) in Germany | 21:25 |
| de-facto | hence Delta peak just about to become visible | 21:25 |
| Brainstorm | New from FDA Press Releases: FDA: Coronavirus (COVID-19) Update: July 2, 2021 → https://is.gd/Crk4jf | 21:29 |
| Brainstorm | Updates for Algeria: +475 cases (now 140550), +9 deaths (now 3735) since 21 hours ago — France: +38 deaths (now 111183) since 18 hours ago | 21:29 |
| -RSSBot[LjLmatrix- Recent Commits to links:master: Add UK vaccine surveillance reports page ( https://github.com/ljl-covid/links/commit/cea302252a5586765ce451f477333d1dfacd8de6 ) | 21:33 | |
| de-facto | but what is it in Spain, Delta taking over from Portugal? | 21:36 |
| -RSSBot[LjLmatrix- Recent Commits to links:master: Add preprint on UK vaccine effectiveness with B.1.617.2 ( https://github.com/ljl-covid/links/commit/15afe6aa94da4b9294ae01b53eb3fab8b152b2e9 ) | 21:38 | |
| -RSSBot[LjLmatrix- Recent Commits to links:master: Add UK government variants surveillance page to Epidemiology ( https://github.com/ljl-covid/links/commit/279aee5b8b33ec577501508eb6ffd5b4568df8ef ) | 21:38 | |
| Brainstorm | New from https://covid19.specops.network : Add UK government variants surveillance page to Epidemiology: It may be out of place as it's the only link in Epidemiology that actually talks about variants, but it seems to me that's where it belongs. → https://is.gd/DARU7N | 21:39 |
| nixonix | el pais is a decent paper, google site:elpais.com for spanish info | 21:40 |
| nixonix | they had high cases in catalonia awhile back | 21:40 |
| nixonix | btw that scottish study showed a bit more reduced vacc effect on indian variant than the one from england | 21:43 |
| nixonix | .title https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(21)01358-1/fulltext | 21:43 |
| Brainstorm | nixonix: From www.thelancet.com: SARS-CoV-2 Delta VOC in Scotland: demographics, risk of hospital admission, and vaccine effectiveness - The Lancet | 21:43 |
| LjL | another country where Delta is definitely taking hold, although I didn't check it earlier since I assumed the EU spike came from bigger countries: http://offloop.net/covid19/?default=Greece&cumulative=no&smooth=yes | 21:44 |
| nixonix | i wonder whats its prevalence in ireland | 21:44 |
| de-facto | it looks the same in every EU country R~1.3 meaning October like peak | 21:45 |
| de-facto | just that its in the middle of the summer, so seasonality will accelerate it from now on while vaccinations slow it down | 21:46 |
| nixonix | could be variance partly. also the cases are lower in weekend and early week days, so they are higher around wed-sat or so | 21:46 |
| de-facto | hence as long as incidence still is low it can be controlled somewhat cheaply with NPIs compared to when politicians hesitate and tolerate incidence to grow up to a "critical" value where they have no choice but to react with a strict lockdown | 21:47 |
| nixonix | or they just decide that old ppl are protected now, so no more restrictions | 21:47 |
| de-facto | no variance there, its Delta, i did exponential fits on pure delta sequences, its got R~1.3 in Germany and in UK aswell | 21:48 |
| nixonix | let our kids get brain damage and short telomeres... well, only a few of them have ever heard about those studies, tho | 21:48 |
| de-facto | so i assume when we see R~1.3 we can be pretty sure its Delta | 21:48 |
| nixonix | "we just didnt know!" | 21:48 |
| de-facto | Vaccinations are too slow, we need NPIs immediately put in place | 21:49 |
| nixonix | i just searched finnish articles on that brain image study. i know there was one, but it was in a small web media of a political party. i found one more, it was behind paywall | 21:50 |
| nixonix | i think 0 about telomeres. i just checked with a media search that shows only the 2 last weeks, there was none | 21:50 |
| nixonix | i found a 2013 article in a paper inteneded for finnish md's, influenza associated to shortened telomeres | 21:52 |
| nixonix | nothing about telomeres in finnish media, related to rona | 21:54 |
| nixonix | and the "flu" article was about those with already shorter telomeres were more apt to get rhino 39 | 21:55 |
| nixonix | .title https://jamanetwork.com/journals/jama/fullarticle/1653523 | 21:56 |
| Brainstorm | nixonix: From jamanetwork.com: Association Between Telomere Length and Experimentally Induced Upper Respiratory Viral Infection in Healthy Adults | Hematology | JAMA | JAMA Network | 21:56 |
| nixonix | .title https://www.nejm.org/doi/10.1056/NEJMoa2102137 | 21:58 |
| Brainstorm | nixonix: From www.nejm.org: Comparative Effectiveness of Aspirin Dosing in Cardiovascular Disease | NEJM | 21:58 |
| Brainstorm | New from CIDRAP: COVID-19 surges accelerate in Southeast Asia: Lisa Schnirring | News Editor | CIDRAP News Jul 02, 2021 "In those countries whose hospitals are filling up, they need vaccines and other health tools right now." → https://is.gd/Jte5Ul | 22:00 |
| nixonix | remember electrolytes (some ppl need potassium and sink too) | 22:02 |
| nixonix | .title https://pubmed.ncbi.nlm.nih.gov/33551489/ | 22:02 |
| Brainstorm | nixonix: From pubmed.ncbi.nlm.nih.gov: Magnesium and Vitamin D Deficiency as a Potential Cause of Immune Dysfunction, Cytokine Storm and Disseminated Intravascular Coagulation in covid-19 patients - PubMed | 22:02 |
| nixonix | and reduce table salt | 22:02 |
| nixonix | Skwiersky said the odds of death also were increased twofold for patients who did not have diabetes and whose glucose values exceeded 140 mg/dL. Additionally, these patients had a 3.5-fold raised odds of ICU admission and a 2.3-fold higher odds of intubation and of experiencing acute kidney injury | 22:04 |
| nixonix | https://www.eurekalert.org/pub_releases/2021-03/tes-hcp_1031621.php | 22:04 |
| nixonix | .title | 22:04 |
| Brainstorm | nixonix: From www.eurekalert.org: Hospitalized COVID-19 patients fare worse when they have high blood sugar | EurekAlert! Science News | 22:04 |
| nixonix | sink=zinc | 22:05 |
| nixonix | "The American Journal of Clinical Nutrition warns that high amounts of refined sugars causes a release of inflammatory cytokines | 22:09 |
| nixonix | .title https://advances.sciencemag.org/content/6/16/eaaz7086.full | 22:10 |
| Brainstorm | nixonix: From advances.sciencemag.org: O-GlcNAc transferase promotes influenza A virus–induced cytokine storm by targeting interferon regulatory factor–5 | Science Advances | 22:10 |
| Brainstorm | New from COVID19 Vaccine Tracker: Andy Becker: Altimmune Inc: AdCOVID → https://is.gd/bnKPpU | 22:10 |
| nixonix | These results suggest that IRF5 is at least the major, if not the only, functional OGT target that promotes IAV-regulated cytokine storm | 22:12 |
| nixonix | studied for covid too? | 22:12 |
| nixonix | i wonder whats the correlation of sugar intake and severity of covid. filtered out things like BMI | 22:16 |
| nixonix | .title https://www.studyfinds.org/brown-fat-protects-from-chronic-illnesses/ | 22:19 |
| Brainstorm | nixonix: From www.studyfinds.org: Brown fat may actually protect you from chronic conditions, including diabetes and heart failure - Study Finds | 22:19 |
| nixonix | here there are other ideas, why elevated glucose levels would be a risk factor | 22:30 |
| nixonix | .title https://www.medrxiv.org/content/10.1101/2021.04.29.21256294v1.full | 22:30 |
| Brainstorm | nixonix: From www.medrxiv.org: Elevated Blood Glucose Levels as a Primary Risk Factor for the Severity of COVID-19 | medRxiv | 22:30 |
| de-facto | ofc sugar is pro-inflammatory, its know longtime | 22:30 |
| nixonix | yeah, but mechanisms are important too. they could be treated possibly. just telling ppl cut the sugar during the epidemic has only a limited effect | 22:34 |
| nixonix | many ppl just dont do that even when their feet are going to get amputated. go see those grannies in hospitals | 22:35 |
| nixonix | i dont know if you could increase your brown fat somehow, like cutting sugar, without gene therapy, but there are drugs that can activate it | 22:36 |
| nixonix | then those metabolic pathways like the one involving IRF5 could be targets perhaps | 22:40 |
| Brainstorm | New from Shane Crotty: @profshanecrotty: More robust evidence that breakthrough infections in vaccinated people are milder and less likely to transmit.A large and well done study. → https://is.gd/F3hTCA | 22:41 |
| nixonix | "From December 14, 2020, to April 10, 2021" - in usa, so mix of older 614g, uk kent, P.1, cali 452R etc | 22:46 |
| nixonix | but not 617.2 - there was lots of breakthroughs among double vaccd, mostly pfizer, healthcare personnel in a finnish hospital | 22:47 |
| nixonix | Of the 42 infected staff members, 17 had received both vaccine doses and two the first dose. The other staff members were unvaccinated because they were either not part of the regular staff or not involved in patient care | 22:49 |
| nixonix | so it looks like a lot depends on viral dose. even with double vacc, try to keep it minimal | 22:49 |
| nixonix | with 617.2 around, that is. or SA or braz variant etc | 22:50 |
| nixonix | In 14 cases (63.6%), occupational infections occurred while using a surgical mask, and all infections originating from patients occurred while using a surgical mask or no mask at all. No occupational infections were found while using an FFP2/3 respirator | 22:52 |
| nixonix | .title http://ijomeh.eu/Sources-of-healthcare-workers-COVID-19-infections-and-related-safety-guidelines,132898,0,2.html | 22:53 |
| Brainstorm | nixonix: From ijomeh.eu: Sources of healthcare workers’ COVID‑19 infections and related safety guidelines | 22:53 |
| nixonix | bad masks create wrong sense of security, while making hearing the speech harder, with no lip reading thats part of the process, and recuires to rise the voice, reducing distance etc | 22:54 |
| nixonix | .title https://www.bbc.com/news/health-57636360 | 22:55 |
| Brainstorm | nixonix: From www.bbc.com: Covid: Masks upgrade cuts infection risk, research finds - BBC News | 22:55 |
| nixonix | raise.. | 22:55 |
| LjL | I wonder if FFP3 there is just because "why not" since the article doesn't in any way compare FFP2 to FFP3 | 23:00 |
| nixonix | .title https://link.springer.com/article/10.1007/s40278-021-97804-1 | 23:04 |
| Brainstorm | nixonix: From link.springer.com: PRAC June 2021 meeting highlights: COVID-19 vaccine AEs | SpringerLink | 23:04 |
| nixonix | those certified FFP2 are prob pretty good, esp when professionals use them, getting the nose seal right. so not much bypass flow, like among common folks | 23:05 |
| nixonix | theres your JAK inhibitor (mentioned in that EMA review article, for possible signals for cardiovasc events and cancer): | 23:11 |
| nixonix | XELJANZ (tofacitinib) is the first and only pill of its kind (JAK inhibitor) that treats adults with moderate to severe rheumatoid arthritis, active psoriatic arthritis, and moderate to severe ulcerative colitis | 23:11 |
| nixonix | (if real, or even too common, doesnt mean other JAKi would have similar risks) | 23:12 |
| Brainstorm | New from r/WorldNews: worldnews: Saline water administered instead of vaccine in Mumbai, India → https://is.gd/u2ZxPv | 23:13 |
| nixonix | .title https://www.themoscowtimes.com/2021/06/25/russian-vaccine-skeptics-rush-to-buy-fake-covid-jab-certificates-a74348 | 23:16 |
| Brainstorm | nixonix: From www.themoscowtimes.com: Russian Vaccine Skeptics Rush to Buy Fake Covid Jab Certificates - The Moscow Times | 23:16 |
| nixonix | At the low end of the black market, Russians can get a paper booklet certifying they were vaccinated for 2,000 rubles ($28, 23 euros). At the top end, for 30,000 rubles ($400, 350 euros) middlemen say they can get a medical worker to pour out vaccine doses and upload falsified medical records to the government portal | 23:17 |
| nixonix | it looks like russia is now suffering from blacklash, after their anti-inovio, anti-az, and later anti-pfizer and mrna vacc campaigns. now russians dont trust in their own vaccines | 23:20 |
| nixonix | A troubled public relations campaign is to blame for Russians’ distrust of vaccines, said Pavel Volchkov, the head of the Genome Engineering Lab at the Moscow Institute of Physics and Technology. | 23:22 |
| nixonix | He pointed to Russian state television channels highlighting extremely rare adverse reactions for some individuals abroad who received AstraZeneca and Pfizer-BioNTech vaccines. Though those vaccines are not available in Russia, the news reporting contributed to a fear of all vaccines, he said | 23:22 |
| Brainstorm | New from Reddit (test): nCoV: Scientists quit journal board, protesting ‘grossly irresponsible’ study claiming COVID-19 vaccines kill | 01JUL21 → https://is.gd/2KO2KN | 23:23 |
| nixonix | .title https://www.themoscowtimes.com/2021/03/24/trial-subjects-for-russias-second-coronavirus-vaccine-urge-probe-into-effectiveness-a73351 | 23:24 |
| Brainstorm | nixonix: From www.themoscowtimes.com: Trial Subjects For Russia's Second Coronavirus Vaccine Urge Probe Into Effectiveness - The Moscow Times | 23:24 |
| nixonix | Their analysis of 116 members of the Phase 3 clinical trials, which were launched in mid-November, shows 52 failed to develop antibodies. Given that only 25% of the total 3,000 participants in the trial were given a placebo, the group calculated the likelihood that all 52 in their independent analysis were in the placebo group — and thus would | 23:25 |
| nixonix | not be expected to produce antibodies — at just one in 333,000 | 23:25 |
| dTal | UK vaccine acceptance is incredibly high, internationally speaking | 23:25 |
| dTal | I wonder why that is | 23:25 |
| nixonix | yeah, its higher than in spain for covid vacc. spain used to be among the top pre sars2 | 23:25 |
| nixonix | its because the uk press has been very... supportive for even the home made az. no critical words | 23:26 |
| nixonix | and maybe less antivaxers there, idk | 23:27 |
| nixonix | but in israel, for over 16 yo 2 dose is over 80% and 1st dose over 85% | 23:28 |
| nixonix | they just started to vacc 12-15, with less popularity when cases used to be very low and press writing about myocarditis | 23:28 |
| nixonix | and with large share of arabs and ultras in israel, who are less willing to take the jab, those percentages are superb | 23:30 |
| nixonix | .title https://www.usnews.com/news/health-news/articles/2021-06-25/99-of-new-us-covid-hospitalizations-deaths-occurring-among-the-unvaccinated | 23:33 |
| Brainstorm | nixonix: From www.usnews.com: 99% of New U.S. COVID Hospitalizations, Deaths Occurring Among the Unvaccinated | Health News | US News | 23:33 |
| nixonix | its the intermediate state when the vaccine coverage is still increasing. when its 100%, it will be the other way around - all of them died and in hospitals will be vaccinated! | 23:35 |
| nixonix | so antivaxers getting the last laugh? | 23:35 |
| Brainstorm | Updates for Zimbabwe: +1442 cases (now 52663), +33 deaths (now 1841) since 23 hours ago — Canada: +25 deaths (now 26312) since 21 hours ago | 23:39 |
| dTal | you know what I find really weird | 23:56 |
| dTal | when you plot "confirmed infections per capita per day" for different countries on a log scale, a lot of them have the same distinctive shape | 23:57 |
| dTal | but, highly displaced in time | 23:57 |
| dTal | i.e. some countries do it twice as fast as others | 23:58 |
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