| Arsanerit | misstep? | 00:01 |
|---|---|---|
| nixonix | "tweet not found", that derek lowes. what was it about, that i wrote above about? israel and 64%, breakthroughs and 3rd dose need? | 00:01 |
| nixonix | https://twitter.com/Dereklowe/status/1413613557057572874 | 00:02 |
| nixonix | ab response from the 3rd dose is said to be 5 times or more higher than after 2nd. cant remember the source, tho... | 00:05 |
| nixonix | but we really want new version for indian VOC | 00:05 |
| nixonix | quotes above from these links: | 00:10 |
| nixonix | .title https://www.fiercepharma.com/pharma/gsk-and-vir-tune-their-sotrovimab-pitch-heels-delta-busting-variant-data | 00:10 |
| Brainstorm | nixonix: From www.fiercepharma.com: GSK and Vir, navigating early antibody pitfalls, tout delta variant-busting data for latecomer sotrovimab | FiercePharma | 00:10 |
| nixonix | .title https://www.biorxiv.org/content/10.1101/2021.05.09.442808v1 | 00:11 |
| Brainstorm | nixonix: From www.biorxiv.org: A human antibody that broadly neutralizes betacoronaviruses protects against SARS-CoV-2 by blocking the fusion machinery | bioRxiv | 00:11 |
| dTal | yo I gotta question | 00:14 |
| dTal | so The Virus evolves, yah, and starts to evade the antibodies we've developed for it, which is why variants are more threatening even to the vaccinated | 00:15 |
| dTal | lateral flow tests are keyed to specific proteins in the virus, basically antibodies themselves | 00:16 |
| dTal | so won't the the tests also become less reliable at detecting the presence of variants? | 00:16 |
| dTal | yours truly, Concerned In UK | 00:17 |
| nixonix | depends on regions they use. probably they try to use conserved regions, so they wouldnt be affected, but there arent nearly as reliable as it says in the box | 00:17 |
| de-facto | afaik some rapid tests use proteins that may have less selection pressure, so for example clamp their antibodies onto the N-protein | 00:18 |
| dTal | I mean I assume vaccines also try to use conserved regions | 00:18 |
| nixonix | and then self-sampling, increases a lot false negatives | 00:18 |
| nixonix | vaccines have whole s-proteins, slightly modified. immune response then does what it wants | 00:18 |
| dTal | ah by "regions" you mean of the s-proteins | 00:19 |
| dTal | not of the whole virus | 00:19 |
| nixonix | but they could use another modified protein that has multiple times some conserved regions, like that one in the study above. as another protein besides S | 00:19 |
| dTal | de-facto: hehe but the tests create selection pressure | 00:20 |
| nixonix | no, just some epitopes, those lateral flow tests (and other tests too) | 00:20 |
| dTal | epitope? | 00:20 |
| nixonix | region that antibodies target | 00:20 |
| dTal | is that pronounced like epitome | 00:20 |
| nixonix | how is epitome pronounced? im a foreigner... | 00:20 |
| dTal | not like epitome, I'd lay money | 00:21 |
| de-facto | dTal, that is true indeed | 00:21 |
| dTal | er, epitope | 00:21 |
| dTal | eh-pit-oh-mee | 00:21 |
| dTal | it is NOT eh-pee-tome | 00:22 |
| de-facto | dTal, diversity in tests is a good thing in guess | 00:22 |
| nixonix | could you spell both with IPA? | 00:22 |
| de-facto | indeed using all the same tests would create selection pressure, as soon as a mutation could slip through the tests (false negative) it would have an reprodution advantage | 00:22 |
| dTal | I'd struggle even with a light seltzer water | 00:23 |
| de-facto | btw thats also the reason they use multiple primers in PCR | 00:24 |
| de-facto | the famout s-gene dropout for some variants | 00:24 |
| dTal | (that was a joke, and I don't really know enough IPA, sorry) | 00:24 |
| de-facto | e.g. if they use 3 primers and 1 drops out, they know its there due to the other two amplifying, but they also know that it evaded one primer by a specific mutation on that location | 00:25 |
| de-facto | so primers can be designed to quickly test for a specific VoC | 00:28 |
| nixonix | ˈɛpɪtəʊp | 00:33 |
| nixonix | some finnish soccer hooligans that got tested in russia, said they took the sample inside the cheek | 00:39 |
| LjL | dTal, the test becoming less reliable is the reason the UK fortuitously found itself with a test that can detect whether or not you have the UK variant. but that was a PCR tests that tested, i think, three locations. rapid tests that test just one, well... did we ever really thought they were *considerably* better than tossing a coin? | 00:39 |
| de-facto | how much of the variation space defined by a certain distance to the theoretical optimum binding on ACE2 do the variants already fill out yet? | 00:39 |
| nixonix | and one of them said, they took it from top of tongue. then said: go! | 00:39 |
| LjL | <dTal> I mean I assume vaccines also try to use conserved regions ← not necessarily (and certainly not the N-protein so far) because they specifically want to induce *neutralizing* antibodies | 00:40 |
| LjL | antibodies to the S-protein are likely to be that; antibodies to the N-protein are unlikely to be that, even if maybe it's more likely they will stick to a different variant | 00:40 |
| LjL | also | 00:42 |
| LjL | %pr epitome | 00:42 |
| LjL | %pr epitope | 00:42 |
| Brainstorm | LjL, English pronunciation: /ˈɛpɪtˌoʊp/ (CMU, American) — [ˈɛpɪtˌəʊp] (eSpeak, British) — [ˈɛpɪtˌoʊp] (eSpeak, American) → Audio unavailable. | 00:42 |
| Brainstorm | LjL, English pronunciation: /ɪpˈɪtəmi/ (CMU, American) — /ɪˈpɪtəmiː/ (Moby, American) — [ɪpˈɪtəmˌɪ] (eSpeak, British) — [ᵻpˈɪɾəmi] (eSpeak, American) → Audio unavailable. | 00:42 |
| LjL | you're all welcome | 00:42 |
| nixonix | then somebody told a finnish nurse what they did, and she said no wonder russians have been complaining it as a battery | 00:43 |
| nixonix | there are conserved regions on s protein too, especially S2 (like they used in that paper i linked above, for mAb) | 00:44 |
| de-facto | but arent the conserved regions like the RBM hiden when those parts of the S1 are not extended? | 00:46 |
| nixonix | i read about those a little while ago, in some other context, i cant remember exactly what it was about, hmm. but rbd mutates a lot | 00:49 |
| nixonix | btw the latest assumption on 614g, why it was around 20-25% more infective, was because the monomeres spend more time in open confirmation. which i said here already in may 2020 or so, that it should also make it more deadly | 00:52 |
| nixonix | unless there was something else at the same time, that would make it less deadly. and apparently there was, because that open conformation also made it more susceptible to nAbs | 00:53 |
| de-facto | btw nixonix if most of the more evasive mutants are less reproductive in a naive population, would that mean that those fit variants are already close to optimum in the mutation space? | 00:54 |
| nixonix | topol and that other fellow think 617.2 would be | 00:54 |
| nixonix | in the link i pasted earlier | 00:55 |
| de-facto | delta close to optimum? | 00:56 |
| nixonix | https://www.nature.com/articles/s41591-021-01421-7 | 00:56 |
| de-facto | if so vaccination with a delta spike would make evasion of such immunity come with the price of being less fit always | 00:57 |
| nixonix | like supposedly happened with "delta plus" | 00:57 |
| nixonix | among not-immune, that is | 00:57 |
| de-facto | its less fit in naive? | 00:57 |
| nixonix | but among those that have immunity, but partially waned antibodies, it would be more fit. and now majority of westerners belong to at least partially immunized population | 00:58 |
| nixonix | yeah, they think so | 00:58 |
| nixonix | tell me why theres only 3 or so distincnt serotypers of influenza, and 5 for deng, but couple hundred rhinoviruses | 01:02 |
| nixonix | for humans | 01:02 |
| Brainstorm | Updates for Channel Islands: +304 cases (now 5205) since 20 hours ago | 01:03 |
| nixonix | and only one (left) for measles, that is in dead end "single-stranded, negative-sense, enveloped RNA virus of the genus Morbillivirus within the family Paramyxoviridae | 01:04 |
| nixonix | do our vaccines push sars2 in dead end too? or will it be something like deng, possibility for ADE when reinfected from another serotype | 01:05 |
| nixonix | i think most virologists think the former would happen. but it may take a lot of time, and before that, maybe some very distinct serotypes will follow | 01:07 |
| nixonix | the mutation rate should be around half of flu, which has around half of HIV | 01:07 |
| nixonix | but genome of flu (for whole virus? not sure) changes around 1% per year, and SARS2 has changed around 0.2% during the whole epidemic. comparing that way the effective change is even less than 1/2 of flu | 01:09 |
| nixonix | possible that mutation rate includes synonymous mutations, where the rate could be different between those two | 01:10 |
| nixonix | btw, unlike british news about their self-reporting system has said, that sniffles would be common symptom now with indian variant, those finnish soccer hooligans didnt mention sniffles often. and they had over 90% indian variant | 01:13 |
| de-facto | i see like encircling it with all the vaccination induced immunity around the optimal fitness spot to leave it in its nieche? | 01:15 |
| de-facto | so evading from there would not only make it less fit in a naive population but even more so in the vaccinated population ? | 01:16 |
| LjL | ii'm confused about this Pfizer thing, are they requesting (and being denied) EUA for a 3rd shot of the same old vaccine, or a variant-specific booster? i assume the former, since the latter isn't even being trialled yet (unlike Modeerna)? | 01:17 |
| nixonix | oh yeah, 3 for flu, as influenza D hasnt infected humans yet. and 5 for dengue, the fifth was announced 2013 (some articles may say theres four) | 01:17 |
| nixonix | has pfizer - or moderna - talked about indian variant targetting version yet? | 01:18 |
| LjL | doubt it | 01:19 |
| nixonix | they have candidates for it, for sure | 01:19 |
| Brainstorm | New from BBC Health: Covid to get worse before it gets better, doctors warn: Medical leaders urge people to act with care including continuing to wear face masks in indoor areas. → https://is.gd/ylVSld | 01:19 |
| LjL | but Moderna has talked about a "one-shot" yearly vaccine, i think | 01:19 |
| nixonix | they just dont want to talk about it. maybe planning to make more money selling old model first... | 01:19 |
| LjL | i mentioned it yesterday as i remembered it was tied to the discussion about the "original", recovered Wuhan sequences, i remember Moderna said they would add those to their "one-shot" vaccine if needed | 01:19 |
| LjL | but i don't remember *where* i read that | 01:20 |
| LjL | de-facto found the relevant paper, and one of its authors works for Moderna, but that's not where it mentions that | 01:20 |
| nixonix | was it that moderna was testing half and half combo, wuhan type and some SA/P.1 optimized version. forgettabout the old variants already, i want the new model, i want it now | 01:21 |
| nixonix | who knows, it could work for years without boosters.. bad for business | 01:25 |
| nixonix | so they are selling the old model as long as theres market. then they will update to SA variant optimized, and when we ask, how about the indian, they say its not ready yet. next year perhaps | 01:26 |
| de-facto | how about gain of function research to get the most optimized version of fitness, then variate that to get a multiplicity of less fit mutants and use those for multivalent vaccinations | 01:28 |
| de-facto | that way the most fit variant, if ever achieved by the pathogen in nature, may be encircled in that tight spot by a gradient of rising neutralization for any evasion try out of that nieche | 01:29 |
| nixonix | they simulate stuff like that in substitution models. idk if cell cultures would offer any benefit. multivalent vaccines for possible emerging variants - i think there could be so many of them, it wouldnt work | 01:33 |
| nixonix | just try to find better universal betacoronavirus vaccines, and either use the knowledge about them to improve the s protein used in vaccine, or do another protein that has multiple times certain conserved epitopes that there are protective response against, for strong ab response against them | 01:36 |
| LjL | today i read that most people born in or after the 80s are safe from shingles because they didn't go through the chickenpox ritual, because they had a vaccine | 01:37 |
| LjL | and i wonder, why didn't i have a vaccine | 01:37 |
| LjL | i have (small) chickenpox scars on my head even | 01:37 |
| pwr22 | We didn't do a chickenpox vaccine here in the uk | 01:37 |
| LjL | maybe italy wasn't privileged enough yet | 01:37 |
| LjL | pwr22, well that's nice | 01:37 |
| pwr22 | At least I didn't have one before I got chicken pox as a kid | 01:38 |
| LjL | i already forgot where i read this though | 01:38 |
| LjL | it was certainly in some discussion about how vaccines are helpful, wrt COVID | 01:38 |
| pwr22 | My dad has never had chickenpox and has never had a chickenpox vaccine so I believe he has to be careful around people with it | 01:38 |
| LjL | maybe twitter thread, will never find again | 01:38 |
| LjL | pwr22, ouch... or, he could get a vaccine? | 01:39 |
| LjL | shingles vaccines are offered to older people here | 01:39 |
| LjL | a shingle vaccine, afaik, is more or less a turbo version of a chickenpox vaccine | 01:39 |
| pwr22 | Yeah it's the same virus right? | 01:40 |
| pwr22 | Maybe my dad has had one now but I don't think we are very proactive at vaccinating anyone but kids | 01:40 |
| pwr22 | I'm pretty sure I missed one or more rounds of vaccines as I was off sick | 01:40 |
| pwr22 | I don't believe I was ever contacted to get it separately | 01:41 |
| pwr22 | They were given in our school | 01:41 |
| LjL | pwr22, it depends on the GP here, they may offer it or not, but one can always ask | 01:41 |
| LjL | and yes it's the same virus | 01:41 |
| LjL | unfortunately it's one of those nasty ones that stay in your body | 01:41 |
| LjL | and shingles is a *bitch* | 01:41 |
| LjL | (although i suppose chickenpox as an adult may be even worse) | 01:41 |
| dTal | wikipedia says it's not the same virus | 01:42 |
| nixonix | Brazzoli et al. evaluated a self-amplifying mRNA that expressed H1 HA from the 2009 pandemic formulated with a cationic nanoemulsion in ferrets | 01:42 |
| dTal | albeit, very closely related | 01:42 |
| nixonix | they have tried to design mrna flu vaccine for many years | 01:42 |
| LjL | dTal, where and what does it say? | 01:42 |
| LjL | %wik varicella | 01:42 |
| Brainstorm | LjL, from English Wikipedia: Chickenpox, also known as varicella, is a highly contagious disease caused by the initial infection with varicella zoster virus (VZV). The disease results in a characteristic skin rash that forms small, itchy blisters, which eventually scab over. It usually starts on the chest, back, and face. It then [... want %more?] → https://en.wikipedia.org/wiki/Chickenpox | 01:42 |
| pwr22 | Ah, I thought it was the same virus becoming active again in your nerves? | 01:42 |
| LjL | The most common late complication of chickenpox is shingles (herpes zoster), caused by reactivation of the varicella zoster virus decades after the initial, often childhood, chickenpox infection.[citation needed] | 01:43 |
| dTal | oh | 01:43 |
| dTal | shingles and chickenpox | 01:43 |
| LjL | Shingles is due to a reactivation of varicella zoster virus (VZV) in a person's body.[1] The disease chickenpox is caused by the initial infection with VZV.[1] Once chickenpox has resolved, the virus may remain inactive in nerve cells.[1] When it reactivates, it travels from the nerve body to the endings in the skin, producing blisters.[7] Risk factors for reactivation include old age, poor immune function, and having had chickenpox before 18 months of age.[1] | 01:43 |
| LjL | https://en.wikipedia.org/wiki/Shingles | 01:43 |
| ketas | but wikipedia has no voice on it's own, how can it say | 01:43 |
| dTal | sorry I jumped in, I assumed you were talking about EBV | 01:43 |
| LjL | EBV is definitely a different virus, not sure it's even closely related | 01:44 |
| LjL | chickenpox is a herpesvirus | 01:44 |
| LjL | EBV is... well, it stays in your body too, they have that in common | 01:44 |
| dTal | okay I've confused myself | 01:44 |
| nixonix | "Coinfection of a cell culture with a human and avian influenza A virus had yielded a recombinant virus with high neurovirulence for mice | 01:44 |
| LjL | but sure, i'd *also* like not to have EBV | 01:46 |
| LjL | but i don't think there's a vaccine for that | 01:46 |
| LjL | i'd also like not to have HSV-1 which is not nearly as bad as shingles but still pretty damn annoying, and i think soon there will be a vaccine for it, for all those lucky kids who unlike me won't get any cold sores all the time ;( | 01:46 |
| pwr22 | > Death occurs in about 1 per 60,000 cases. | 01:47 |
| pwr22 | For chicken pox | 01:47 |
| pwr22 | crazy | 01:47 |
| ketas | how about herpes simplex or several hpv's? | 01:47 |
| ketas | :) | 01:47 |
| pwr22 | How can you die from it? | 01:47 |
| LjL | ketas, i just mentioned HSV-1 | 01:47 |
| LjL | pwr22, well... you can | 01:48 |
| ketas | so you don't have it? :P | 01:48 |
| LjL | if you want to know how, it's by retrograde infection from the trigeminal nerves into the central nervous system, resulting in encephalitis and widespread destruction of brain tissue | 01:48 |
| LjL | don't thank me | 01:48 |
| ketas | most apparently do :/ | 01:48 |
| pwr22 | Oh man that sucks | 01:49 |
| LjL | i do have it | 01:49 |
| LjL | like most people indeed | 01:49 |
| pwr22 | Can shingles also fuck up your brain? | 01:49 |
| LjL | pwr22, not sure | 01:49 |
| ketas | or caries | 01:49 |
| LjL | %wik Clive Wearing | 01:49 |
| Brainstorm | LjL, from English Wikipedia: Clive Wearing (born 11 May 1938) is a British former musicologist, conductor, tenor and keyboardist who suffers from chronic anterograde and retrograde amnesia. He lacks the ability to form new memories, and also cannot recall aspects of his past memories, frequently believing that he has only recently [... want %more?] → https://en.wikipedia.org/wiki/Clive_Wearing | 01:49 |
| pwr22 | So chickenpox kills more people than covid vaccine side effects | 01:49 |
| pwr22 | By several orders of magnitude? | 01:49 |
| LjL | this guy survived a retrograde brain infection from herpes simplex | 01:49 |
| LjL | pwr22, a nasty disease kills more people than a vaccine? i'm not sure if you're surprised, or just saying :P | 01:50 |
| ketas | i have some hpv now | 01:50 |
| ketas | warts are nasty | 01:50 |
| LjL | hmm, most people have that one too, but most are pretty asymptomatic | 01:50 |
| LjL | but i've had graphic descriptions of someone's warts from HPV | 01:51 |
| LjL | wouldn't recommend | 01:51 |
| LjL | also, there's a vaccine for it, but you kinda need to give it to people before they have a sex life | 01:51 |
| ketas | never had any, then 3 on hands, 4 on feet | 01:51 |
| LjL | ugh | 01:51 |
| ketas | i hate them! | 01:51 |
| LjL | i believe you | 01:51 |
| ketas | girl is to be blamed for both | 01:52 |
| ketas | :( | 01:52 |
| ketas | never have sex! | 01:52 |
| ketas | though there are other means to transfer | 01:52 |
| nixonix | it looks like there could be neurotropic influenzas some day, and but humans blood brain barrier is harder to cross than mices | 01:53 |
| ketas | hpv variants aren't good really | 01:53 |
| ketas | it's not just warts | 01:53 |
| pwr22 | In the UK people get verucas a lot as kids. That's the same virus? | 01:54 |
| pwr22 | As warts I mean | 01:54 |
| ketas | which one? | 01:54 |
| ketas | some hpvs cause warts indeed | 01:54 |
| ketas | and it's common | 01:55 |
| ketas | fuck there's one under foot | 01:55 |
| ketas | and one on thumb | 01:55 |
| ketas | there's one on one finger, one on another, on side of foot, side of toe, 3 on other toe | 01:56 |
| ketas | goddamnit sudden outbreak :'( | 01:57 |
| de-facto | interesting, so why dont go go to a MD with a big laser and kill all of them? | 01:57 |
| ketas | i want to | 01:57 |
| ketas | well there's also heat, cold and acid | 01:57 |
| ketas | i have to ask | 01:57 |
| de-facto | just do it, as soon as possible | 01:58 |
| nixonix | when was it ecdc said indian variant will become dominant, august? its already dominant. by august it will be superdominant | 01:58 |
| ketas | i'll just tru to cut some above blood line after some time | 01:58 |
| ketas | that will not really work | 01:58 |
| de-facto | you know they are contagious | 01:58 |
| de-facto | so why dont you let an expert deal with killing them? | 01:59 |
| nixonix | .title https://ca.news.yahoo.com/over-60-russians-dont-want-160018340.html | 01:59 |
| Brainstorm | nixonix: From ca.news.yahoo.com: Over 60% of Russians don't want Sputnik V vaccine, see coronavirus as biological weapon: Reuters poll | 01:59 |
| pwr22 | There's also the duct tape method | 01:59 |
| ketas | we'll i have to get them removed | 01:59 |
| ketas | but they come back | 01:59 |
| nixonix | The Levada Center said a poll it conducted last month showed that 62% of people did not want to get Russia's domestically produced vaccine, and that the highest level of reluctance was identified among 18 to 24-year-olds. | 02:00 |
| nixonix | The poll, which sampled 1,601 people in 50 regions, also found that 64% of people thought the new coronavirus was created as a biological weapon. | 02:00 |
| ketas | could take long time i hearf | 02:00 |
| ketas | well doctors are baf | 02:00 |
| ketas | it's why i have half of my teeth broken too | 02:01 |
| pwr22 | > A 12-week daily treatment with salicylic acid has been shown to lead to a complete clearance of warts in 10–15% of the cases. | 02:01 |
| pwr22 | Doesn't sound very effective ha ha | 02:01 |
| ketas | cold then? | 02:02 |
| ketas | cold sucks i guess | 02:02 |
| ketas | we'll i'll see what gp says | 02:02 |
| pwr22 | I honestly had most luck myself with putting a plaster or duct tape over one I had on my elbow | 02:03 |
| pwr22 | Try some stuff and see what works I guess | 02:03 |
| ketas | fuck i didn't want to have this sex now i have damn warts!!! | 02:03 |
| nixonix | another, more recent poll result was, that 35% didnt want to get vaccinated, though | 02:04 |
| nixonix | Recently the Kremlin admitted that its original goal to vaccinate 60 percent of the population by September will be unachievable, according to a report by TV Rain. Instead, the government has settled for a more realistic 30 percent | 02:04 |
| nixonix | i had a wart in finger | 02:06 |
| nixonix | as a kid | 02:06 |
| ketas | maybe i'll just kill myself, i'm too ruined | 02:06 |
| nixonix | i think it was in thumb, but not sure | 02:06 |
| ketas | how long frozen wounds heal? | 02:07 |
| ketas | i wonder | 02:07 |
| nixonix | wait until there are some nanobots, they will fix it | 02:07 |
| ketas | seems scary | 02:07 |
| ketas | can they connect irc? | 02:08 |
| nixonix | .title https://www.labroots.com/trending/immunology/11919/synthetic-cells-immunotherapy | 02:08 |
| Brainstorm | nixonix: From www.labroots.com: Synthetic T Cells the Next Big Thing in Immunotherapy | Immunology | 02:08 |
| ketas | fuck somebody is ddossing my leg fell off again | 02:09 |
| de-facto | ketas, wtf relax, go do a MD and let them deal with that | 02:09 |
| ketas | wtf | 02:09 |
| ketas | i asked how long wounds heal | 02:09 |
| de-facto | i had some at my foot sole as a kid, went to a MD and they killed them with a CO2 laser, it was 100% success | 02:10 |
| de-facto | no big deal | 02:10 |
| ketas | laser seems cute idea | 02:10 |
| ketas | have wart ash | 02:10 |
| ketas | but doctors suck | 02:11 |
| Brainstorm | New from Shane Crotty: @ashishkjha: RT by @profshanecrotty: A lot of talk today about whether the 159 million fully vaccinated folks need a third shotYou know what would really help?Ensuring the 25M who have 1 shot get their 2ndAnd Ensuring the 100M eligible who have zero shots get their firstThat would help keep everyone safe → https://is.gd/4gIFpW | 02:11 |
| nixonix | now you remember, no premarital sex anymore | 02:11 |
| de-facto | its an established method, go to a MD and get it fixed if it bugs you, its really no big deal, it probably is one of the most common treatments for such skin specialized MDs | 02:11 |
| ketas | girl told it's required for keeping her | 02:12 |
| ketas | so yeah people suck, i have to explain to gp why my pulse is 115 when i visit them, from <70 resting | 02:14 |
| Win7ine | ketas I know the feeling, for me it is elevated BP with the white coat syndrome | 02:18 |
| nixonix | poor aussies. they used to be so happy, media reporting "now 17th donut day in victoria" and stuff like that | 02:19 |
| LjL | pwr22, verucas are caused by HPV, but the kind i think you have in mind are caused by localized HPV, while having HPV in your *system* can also cause warts sometimes, but mostly it's silent, yet correlated with increased odds of various cancers | 02:19 |
| nixonix | or is it doughnut in aus? | 02:19 |
| LjL | the good news: when you get HPV from walking on a pool floor barefoot, though, annoying as the resulting wart will be, you're not getting HPV in your entire system | 02:19 |
| LjL | the bad news: most adults have HPV in their system anyway | 02:19 |
| ketas | it sucks | 02:20 |
| ketas | all the cancers they could give | 02:20 |
| ketas | but can't do anything | 02:20 |
| ketas | btw, thinking of giving psa test | 02:21 |
| LjL | chill | 02:22 |
| LjL | you don't suddenly have prostate cancer because you got a few wards | 02:23 |
| LjL | warts also | 02:23 |
| ketas | ? | 02:23 |
| ketas | oh fuck you, i know it all | 02:23 |
| LjL | okay, then no need to discuss it here in that case | 02:23 |
| ketas | i might as well kill myself right now over "chill" annoyances | 02:24 |
| LjL | are you just telling me that you may kill yourself because i've told you to chill? | 02:24 |
| LjL | you know i have an easy way of ensuring that doesn't happen again | 02:24 |
| ketas | take this rope and attach to this tree i stand next to | 02:25 |
| LjL | because people going around with threats of killing themselves if you do this or that do not impress me | 02:25 |
| LjL | ketas, let me know when you feel comfortable with being unmuted | 02:25 |
| nixonix | "Bizarre moment NSW's chief medical officer uses her mask to wipe her eye bringing the daily Covid press conference to a halt" | 02:25 |
| LjL | ew | 02:26 |
| pwr22 | Oh dear | 02:26 |
| Brainstorm | Updates for Netherlands: +6186 cases (now 1.7 million), +2 deaths (now 17905) since 23 hours ago — Vietnam: +2625 cases (now 26010), +6 deaths (now 110) since 23 hours ago — France: +22 deaths (now 111395) since 23 hours ago — Canada: +647 cases (now 1.4 million), +14 deaths (now 26419) since 23 hours ago | 02:30 |
| LjL | ketas, if you are actually thinking of committing suicide, consider talking to a qualified psychologist or psychiatrist before you go ahead and do it. but in any case, don't be on IRC saying that you will commit suicide *if* someone on IRC doesn't act the way you want them to. that's not okay. | 02:31 |
| nixonix | The Spanish flu ravaged Australia in 1919, leaving 15,000 Aussies dead within a year of the first case arising in January, and killing 50 to 100million people worldwide. Australia's population stood at about five million at the time, and more than a third of all Australians were infected. | 02:31 |
| nixonix | i read quite a bit about spanish flu recently, when we were arguing the IFR of it, and how comparable it was to sars2 | 02:32 |
| nixonix | those death and infection rate estimates were often very off, and varied a lot depending on study | 02:32 |
| nixonix | that would give IFR 0.9%. plausible imo | 02:33 |
| de-facto | .title https://github.com/mbevand/covid19-age-stratified-ifr | 02:33 |
| Brainstorm | de-facto: From github.com: GitHub - mbevand/covid19-age-stratified-ifr: Calculates the age-stratified infection fatality ratio (IFR) of COVID-19 | 02:33 |
| de-facto | thats seasonal influenza though | 02:34 |
| LjL | ketas, anyway my point was just going to be that while we now know, roughly speaking, that certain cancers don't happen if you don't have HPV, still, most people *have* HPV and still mosst of them don't get those cancers. so it will be great if everyone is vaccinated against HPV, but as a presumably young man, i think you're overreacting if you scramble to get a PSA test just because you know you have contracted HPV. | 02:34 |
| LjL | that said, i'm sorry that just repeating to "chill" appeared to brush off your concerns | 02:35 |
| nixonix | those mortalities in github, did they use official covid death figures, not excess mortalities? | 02:37 |
| nixonix | also the total of the epidemic, if its not by age group, in the spring it was more evenly distributed between age groups, and in the fall way more young people, so IFR dropped a lot just from that | 02:38 |
| de-facto | they provide all of their sources and even the script to process them | 02:38 |
| nixonix | then this year there were vaccines | 02:38 |
| de-facto | yes vaccines change this a lot | 02:38 |
| de-facto | i wonder if its only a factor or if it also deforms the exponential curve for IFR | 02:39 |
| nixonix | for finland using excess mortality (median age 42.7 or so), in the spring using excess mortality i got something like 1.6%. but because the death number was low, it isnt that accurate (variance in background noise) | 02:39 |
| nixonix | for NYC until end of april, median age around 38, i got around 1.4%. excess mortality used | 02:40 |
| nixonix | nyc later published another mortality number, that included likely cases | 02:41 |
| nixonix | the original missed all or most those died in home or senior homes. as they did in uk too, or england and wales. idk how it was after the spring | 02:41 |
| LjL | nnixwhich mortalities in github? | 02:42 |
| LjL | oh | 02:42 |
| * LjL whacks himself with a read-the-scrollback bat | 02:42 | |
| nixonix | but then in the fall IFR's generally dropped a lot, if was something like 0.1 or 0.2% in finland too. not many old ppl got infected | 02:42 |
| nixonix | might have been lower than 0.1% even, not sure. flu-like | 02:43 |
| nixonix | then what was left, was still old ppl mostly, and then theres uncertainty for those low numbers, how many of them died because of covid, and how many for other reasons. its hard to find out for sure | 02:44 |
| nixonix | .title https://www.dailymail.co.uk/news/article-9773155/1919-Spanish-Flu-lockdown-current-Sydney-coronavirus-lockdown-bear-striking-similarities.html | 02:45 |
| Brainstorm | nixonix: From www.dailymail.co.uk: 1919 Spanish Flu lockdown and current Sydney coronavirus lockdown bear striking similarities | Daily Mail Online | 02:45 |
| nixonix | .title https://ourworldindata.org/spanish-flu-largest-influenza-pandemic-in-history | 02:46 |
| Brainstorm | nixonix: From ourworldindata.org: The Spanish flu (1918-20): The global impact of the largest influenza pandemic in history - Our World in Data | 02:46 |
| nixonix | .title https://www.thehistorypress.co.uk/articles/the-spanish-flu-pandemic-of-1918/ | 02:47 |
| Brainstorm | nixonix: From www.thehistorypress.co.uk: The History Press | The Spanish Flu pandemic of 1918 | 02:47 |
| Brainstorm | nixonix: From www.thehistorypress.co.uk: The History Press | The Spanish Flu pandemic of 1918 | 02:47 |
| nixonix | uk had much lower death toll, than was estimated for most of europe. but those european numbers were prob way too high, and malnutrition caused most of mortality after the war | 02:48 |
| nixonix | sure there was some effect on both at the same time | 02:48 |
| nixonix | often those ridiculously high mortality estimates come from way too low estimates of prevalence. like for finland. four waves and prevalence would be just 10-15%, not likely | 02:50 |
| nixonix | i mean IFR estimates | 02:50 |
| nixonix | so it wasnt as bad as many articles say | 02:50 |
| nixonix | "coronavirus called OC43 may have caused the 'Russian flu' | 02:52 |
| nixonix | which was 1889-90. a bit later to give immunity for those, that were less affected from spanish flu, as those born at russian flu time werent all protected, so it wasnt the same type flu in russian flu | 02:55 |
| nixonix | but something before russian flu gave those over 40 or so immunity for spanish flu | 02:55 |
| nixonix | and it was very long lasting partial immunity | 02:56 |
| nixonix | apparently plasma cells in bone marrow | 02:56 |
| nixonix | do we get those for sars2, from current vaccines? | 02:57 |
| nixonix | if we do, are the abs high enough titers, and are they protective type? | 02:59 |
| nixonix | do they protect also from cns and chromosome damage? | 03:01 |
| Brainstorm | New from BBC Health: Covid: Fully jabbed NHS staff may not have to isolate: Health leaders urge the government to change quarantine rules to avoid severe staff shortages. → https://is.gd/SKlKKd | 03:04 |
| nixonix | they were wondering why those later (than the one pre russian flu) flus didnt give protection for spanish flu, with adaptive cell mediated immunity that should be well conserved | 03:07 |
| nixonix | It is possible that the recall of pre-existing influenza virus-specific CD8+ T cell responses was not rapid enough for the extremely virulent 1918 pandemic virus, causing rapid appearance of clinical disease and death within 3 days (Ahmed et al., 2007). Alternatively, pandemic H1N1 influenza viruses (1918 and 2009) may have suppressed immunogenic | 03:08 |
| nixonix | RIPK3-driven dendritic cell death needed for the induction of an effective CD8+ T cell response | 03:08 |
| nixonix | ref the news link above: | 03:10 |
| nixonix | "Of the 42 infected staff members, 17 had received both vaccine doses and two the first dose. The other staff members were unvaccinated because they were either not part of the regular staff or not involved in patient care | 03:10 |
| nixonix | matrix protein of the 1918 virus already contained extra-epitopic amino acid residues that were associated with evasion from the pre-existing influenza virus CD8+ T cells (van de Sandt et al., 2015b), a phenomenon not observed in the comparatively mild 2009 pandemic influenza virus | 03:13 |
| Win7ine | nixonix what is it you are trying to say? | 03:19 |
| nixonix | about what, spanish flu, lasting of vaccine protection, those double vaccinated hcw protection or something else? | 03:20 |
| Win7ine | seems you are grabbing info left and right and repost here. what is your point or understanding? | 03:20 |
| nixonix | why are you asking? | 03:21 |
| Win7ine | because I am reading your lines | 03:21 |
| nixonix | ok. about which of those topics i mentioned, you want to know the point? | 03:22 |
| Win7ine | All | 03:22 |
| nixonix | well, read again, and if something isnt clear, just ask | 03:23 |
| Win7ine | Your monologue needs a purpose in your own understanding | 03:23 |
| Win7ine | THe question is what is your pouint | 03:24 |
| nixonix | i was reading about spanish flu, and saw some connections to understanding this epidemic | 03:24 |
| Win7ine | There is no connection except the one you suppose | 03:25 |
| nixonix | so what you really want to say, i shouldnt paste quotes or my thought about them here? | 03:25 |
| nixonix | it annoys you? | 03:25 |
| nixonix | thoughtS | 03:25 |
| Win7ine | Quotes are a means of to your own understading, if you have soemthing to say do it in clear words, stop quoting and diffusing | 03:27 |
| nixonix | so it annoys you and you are asking me to stop? | 03:27 |
| Win7ine | I still do not know what you want to say | 03:27 |
| Win7ine | If you want discussion you need to open one and stop being static with other peoples quotes on 50 topics | 03:28 |
| nixonix | i hoped they might induce some discussion, but i suppose its too late | 03:29 |
| nixonix | anyway, they interest me and are close to this sars2 epidemic | 03:29 |
| nixonix | if they annoy you, just stop reading | 03:30 |
| nixonix | or ignore me | 03:30 |
| Win7ine | Bombardement seldom leads to speech | 03:30 |
| Win7ine | Do you have anybody else communicating with you? | 03:30 |
| nixonix | you really try hard to make me write like you want, do you | 03:30 |
| nixonix | how about taking care of your own business instead of others? | 03:31 |
| Win7ine | Ok, for the last time, what is your business and what are you trying to say? | 03:32 |
| nixonix | i said it above :) | 03:32 |
| Brainstorm | Updates for Zimbabwe: +2683 cases (now 65066), +55 deaths (now 2084) since a day ago | 03:32 |
| Win7ine | You said nothing, only quoted others | 03:32 |
| nixonix | the quotes were related to protectivity of long lasting immunity, with spanish flu, and also if the same would happen with sars2, natural immunization or with vaccines | 03:34 |
| Win7ine | And you said nothing | 03:34 |
| Win7ine | What is your business | 03:35 |
| Win7ine | Quotes are easy for BOTs, what is *YOUR* business? | 03:36 |
| Win7ine | nixonix what is your buisness and if you have a thought what is it you want to say? | 03:38 |
| de-facto | .title https://www.nature.com/articles/s41586-021-03647-4 | 03:38 |
| Brainstorm | de-facto: From www.nature.com: SARS-CoV-2 infection induces long-lived bone marrow plasma cells in humans | Nature | 03:38 |
| Brainstorm | Updates for Aruba: +25 cases (now 11169) since 7 days ago | 04:09 |
| Brainstorm | Updates for Thailand: +9326 cases (now 326832), +91 deaths (now 2625) since 23 hours ago — South Korea: +1378 cases (now 166722), +2 deaths (now 2038) since 23 hours ago — Netherlands: +6561 cases (now 1.7 million), +2 deaths (now 17906) since 23 hours ago — France: +20 deaths (now 111400) since 23 hours ago | 04:59 |
| LjL | that was unpleasant | 05:27 |
| Brainstorm | New from The Indian Express: World: South Korea reports third consecutive record high new Covid-19 cases → https://is.gd/O8Zic7 | 05:58 |
| Brainstorm | New from r/WorldNews: worldnews: Amid the misery of a pandemic that has claimed at least four million lives, the scientific search for its origins has itself become toxic. → https://is.gd/w9e7F5 | 06:58 |
| Brainstorm | Updates for Belgium: +1223 cases (now 1.1 million), +2 deaths (now 25198) since a day ago | 07:03 |
| Brainstorm | New from The Indian Express: World: CDC issues new school guidance, with emphasis on full reopening → https://is.gd/Cbp9dO | 07:29 |
| Brainstorm | Updates for England, United Kingdom: +30724 cases (now 4.4 million), +22 deaths (now 112880) since a day ago — Florida, United States: +23747 cases (now 2.4 million), +172 deaths (now 38157) since 7 days ago — Missouri, United States: +2142 cases (now 636976), +7 deaths (now 9799) since a day ago [... want %more?] | 07:41 |
| joerg | what been the recommended analgetikum to treat vax reactions? | 07:49 |
| joerg | Parazetamol? Ibu? I guess no ASS, right? | 07:49 |
| joerg | hmm, nm | 07:57 |
| spybert | Ibuprofen seems to work fine | 08:01 |
| joerg | thanks | 08:09 |
| joerg | had a half one already | 08:09 |
| joerg | at least I know the jab works ;-) | 08:10 |
| joerg | meanwhile 5.8 in D | 08:14 |
| joerg | yesterday 5.5 | 08:14 |
| Brainstorm | Updates for India: +42766 cases (now 30.8 million), +1030 deaths (now 406752) since 15 hours ago — Laos: +93 cases (now 2630) since 23 hours ago | 08:43 |
| Brainstorm | New from r/Coronavirus: Daily Discussion Thread | July 10, 2021: Please refer to our Wiki for more information on COVID-19 and our sub. You can find answers to frequently asked questions in our FAQ , where there is valuable information such as our: → https://is.gd/G8i3F9 | 09:10 |
| Brainstorm | New from Reddit (test): CoronaVirus_2019_nCoV: ‘Literally killing people’: Jen Psaki unleashes truth bomb on GOP governor’s vaccination ‘disinformation’ → https://is.gd/XJuEy8 | 09:20 |
| Brainstorm | Updates for Japan: +2848 cases (now 816242), +36 deaths (now 14933) since 23 hours ago | 10:59 |
| Brainstorm | New from The Indian Express (Health): Health: Sickle cell anemia and Covid-19: All you need to know → https://is.gd/5keExm | 11:13 |
| Brainstorm | New from r/WorldNews: worldnews: Sri Lanka reopens many places after 2 months of Covid-19 lockdown → https://is.gd/56Zh0S | 11:33 |
| Brainstorm | Updates for Isle of Man: +12 cases (now 1671) since a day ago | 11:37 |
| indoanon[m] | test | 12:06 |
| Brainstorm | New from Gazzetta Ufficiale italiana: AGENZIA ITALIANA DEL FARMACO - DETERMINA 5 luglio 2021: Modifica della classificazione ai fini della fornitura dei vaccinianti influenzali. (Determina n. DG/792/2021). (21A04242) → https://is.gd/WX5od5 | 12:24 |
| Brainstorm | Updates for Malaysia: +9353 cases (now 827191), +87 deaths (now 6067) since 23 hours ago — N. Cyprus: +259 cases (now 8860) since 2 days ago — Germany: +857 cases (now 3.7 million) since 23 hours ago | 13:04 |
| * pwr22 uploaded an image: (46KiB) < https://libera.ems.host/_matrix/media/r0/download/shortestpath.dev/VqfdtpJkuzsbubVyWdwefbbf/Screenshot_20210710-121046~2.jpg > | 13:13 | |
| pwr22 | Oh no | 13:13 |
| pwr22 | First find I've ever got one of them | 13:13 |
| Brainstorm | New from This Week In Virology: TWiV 778: COVID-19 clinical update #70 with Dr. Daniel Griffin: In COVID-19 clinical update #70, Daniel Griffin discusses efficacy of portable air cleaners, vaccine induce serum neutralizing antibodies against variants, prevention and attenuation of disease with mRNA vaccines, ivermectin to prevent hospitalization, IL-6 [... want %more?] → https://is.gd/YLEuhe | 13:46 |
| de-facto | pwr22, oh contact tracing app got too many flagged beacons? | 14:02 |
| Brainstorm | Updates for Malta: +109 cases (now 30960) since a day ago — Nepal: +1353 cases (now 654212), +22 deaths (now 9362) since a day ago | 14:06 |
| de-facto | pwr22, do you know the exact point in time? | 14:08 |
| de-facto | or at least an approximation? | 14:08 |
| Brainstorm | New from r/WorldNews: worldnews: Covid-19 originated naturally and not in lab, virologists conclude → https://is.gd/lonLeO | 14:38 |
| Brainstorm | New from r/WorldNews: worldnews: EU reaches 70 percent vaccine delivery goal for adults → https://is.gd/Oa8MBL | 14:48 |
| Brainstorm | New from r/WorldNews: worldnews: Covid-19: Delta variant can evade antibodies that target certain parts of virus → https://is.gd/Z5Rsye | 14:59 |
| Brainstorm | Updates for Bangladesh: +12213 cases (now 1.0 million), +185 deaths (now 16189) since 22 hours ago | 15:08 |
| de-facto | .title https://imgur.com/a/PHEGJRr https://i.imgur.com/4GCe8fS.png "COVID Cases by origin of transmission settings in Germany" src: https://www.rki.de/DE/Content/InfAZ/N/Neuartiges_Coronavirus/Situationsberichte/Jul_2021/2021-07-06-de.pdf?__blob=publicationFile | 15:44 |
| Brainstorm | de-facto: From imgur.com: COVID Cases by origin of transmission settings in Germany - Album on Imgur | 15:44 |
| Brainstorm | New from r/WorldNews: worldnews: Russia reports record high daily COVID-19 deaths, over 25,000 new cases → https://is.gd/riPgMi | 15:49 |
| Brainstorm | New from Scientific American: Health: Let's Use the Lessons from COVID to End HIV → https://is.gd/okV13X | 16:20 |
| -RSSBot[LjLmatrix- Feed: Dichiarazione del Presidente del Consiglio Mario Draghi ( https://www.governo.it/it/articolo/dichiarazione-del-presidente-del-consiglio-mario-draghi/17427 ) | 16:25 | |
| Brainstorm | New from r/WorldNews: worldnews: G20: World must invest at least $75 billion to prevent COVID-19 repeat → https://is.gd/GnvB0p | 16:30 |
| Brainstorm | Updates for India: +1423 deaths (now 407145) since 23 hours ago | 16:35 |
| de-facto | .title https://imgur.com/a/Reml6GA https://i.imgur.com/cOZpHbm.png "COVID Germany: Cases and outbreaks in childrens daycare centers" src: https://www.rki.de/DE/Content/InfAZ/N/Neuartiges_Coronavirus/Situationsberichte/Jul_2021/2021-07-06-de.pdf?__blob=publicationFile | 16:48 |
| de-facto | .title https://imgur.com/a/11PM3kc https://i.imgur.com/jN5wRgQ.png "COVID Germany: Cases and outbreaks in schools src: https://www.rki.de/DE/Content/InfAZ/N/Neuartiges_Coronavirus/Situationsberichte/Jul_2021/2021-07-06-de.pdf?__blob=publicationFile" | 16:58 |
| Brainstorm | de-facto: From imgur.com: COVID Germany: Cases and outbreaks in schools - Album on Imgur | 16:59 |
| pwr22 | de-facto: no useful information provided to me but it says I need to self isolate for 4 days apparently | 17:20 |
| joerg | https://www.sueddeutsche.de/wissen/coronavirus-mutante-b117-daten-1.5197700 ooops this isn't about the today's situation, weird, it looks like it was | 17:29 |
| sKep | hi | 17:51 |
| sKep | any inferences regarding new wave in India | 17:51 |
| sKep | BTW I am listening to KIZ rossman | 17:52 |
| Brainstorm | Updates for United Kingdom: +31800 cases (now 5.1 million) since 15 hours ago | 18:02 |
| LjL | pwr22: is the UK app anonymous and does it use the Google framework? I don't remember anymore, I think it was one of the countries that wanted to do it their own way | 18:16 |
| Brainstorm | New from r/Coronavirus: Coronavirus: Netherlands reports 10,345 new coronavirus cases, an increase of 803% from last week → https://is.gd/2ceh29 | 18:34 |
| Brainstorm | Updates for Myanmar: +4377 cases (now 188752), +71 deaths (now 3756) since a day ago | 18:39 |
| Arsanerit | how is it even possible to do it without the google framework? | 18:46 |
| Brainstorm | New from Reddit (test): China_Flu: EU regulator: mRNA coronavirus vaccines possibly linked to heart swelling → https://is.gd/vnKM3h | 18:54 |
| LjL | Arsanerit: by keeping a foreground notification so the app never gets killed | 19:00 |
| LjL | Other than that, the various Bluetooth stuff is stuff that can be done unprivileged, on Android | 19:00 |
| LjL | On iOS that's different, so AFAIK some country's app actually uses nearby Android devices as "bridge" devices in case two iOS devices need to talk | 19:01 |
| Arsanerit | creative | 19:02 |
| Brainstorm | Updates for Greece: +2327 cases (now 437345), +2 deaths (now 12763) since a day ago — Italy: +1394 cases (now 4.3 million), +12 deaths (now 127768) since a day ago — Faroe Is.: +20 cases (now 845) since a day ago | 19:04 |
| Brainstorm | New from The Indian Express: World: Indonesia short on oxygen, seeks help as Covid cases soar → https://is.gd/O7Luf3 | 19:15 |
| Brainstorm | Updates for Morocco: +1566 cases (now 541405), +9 deaths (now 9360) since 22 hours ago — Malawi: +512 cases (now 38946), +8 deaths (now 1242) since a day ago | 20:06 |
| Brainstorm | New from r/WorldNews: worldnews: Ursula von der Leyen says EU has reached Covid vaccine target → https://is.gd/AyXw1Z | 20:17 |
| Brainstorm | New from r/WorldNews: worldnews: Seoul heads for lockdown as infections spiral in South Korea | Coronavirus → https://is.gd/jTxwyg | 20:27 |
| kreyren[m] | Is there any medical room full of people like de-facto that i can bother with medical questions~ | 20:33 |
| * kreyren[m] needs to upgrade his medkit and lacks info for it while wanting to avoid long research u.u | 20:36 | |
| ublx | yes kreyren[m] but it is a top secret room that admits only people who know how to stock a medkit | 20:43 |
| ublx | joking apart, what exactly are you going to do with this medkit if you don't know what to put in it? kinda seems like the knowledge/skill to use it is more or less equivalent to the knowledge needed to make use of it | 20:47 |
| ublx | *ahem* edit: hrm | 20:48 |
| LjL | ublx, hi | 20:54 |
| ublx | evening, LjL | 20:55 |
| ublx | kreyren's question makes me wonder whether popular first-aid training course providers now offer covid-specific training | 20:59 |
| ublx | i'm imagining that must be a thing already | 20:59 |
| kreyren[m] | ublx: i know what to put in it, but there are apparently better alternatives like the human glue for open wounds~ | 21:00 |
| kreyren[m] | and i need something better for burns bcs the thing i have now is useless u.u | 21:00 |
| kreyren[m] | well i had HA but dunno about it o.o | 21:00 |
| kreyren[m] | ublx: O.o What would you even do in covid-specific things | 21:01 |
| kreyren[m] | do you just get a vaccine and poke it in the people~ | 21:01 |
| kreyren[m] | or remdesivir i guess | 21:01 |
| kreyren[m] | O.o | 21:01 |
| ublx | oh, i thought that was the drift of your interest here, since this is ##covid-19 | 21:02 |
| kreyren[m] | at least that's what CZ doctors seems to be still using to treat covid-19 in ICU 🤔 | 21:02 |
| kreyren[m] | ow u.u | 21:02 |
| ublx | isn't there a prepper's channel that might help with general ideas? | 21:02 |
| kreyren[m] | i was thinking about getting the breathing mask but none does mouth to mouth resucitation anyway | 21:02 |
| kreyren[m] | ublx: prepper? O.o | 21:03 |
| kreyren[m] | that room full of people who think zombies are real and just want me to get lots of guns and axes in my medkit? | 21:03 |
| ublx | oh. there is #prepping, but there's only 20 in it. not promising | 21:04 |
| kreyren[m] | u.u | 21:04 |
| kreyren[m] | LjL: make #medicine or something u.u | 21:04 |
| kreyren[m] | i believe in you~ | 21:04 |
| LjL | no | 21:05 |
| kreyren[m] | whyyyy | 21:05 |
| LjL | also it already exists | 21:05 |
| kreyren[m] | o.o | 21:05 |
| LjL | and at least on freenode, it mostly sucked | 21:05 |
| kreyren[m] | oh i remember that now | 21:05 |
| kreyren[m] | never got answer there and people were really ackward x.x | 21:05 |
| LjL | but no channel that has people with some sense in their head will give you actual medical advice | 21:06 |
| kreyren[m] | and didn't smell doctor-y | 21:06 |
| kreyren[m] | i don't need advice i need info~ | 21:06 |
| LjL | de-facto isn't a "doctor" (at least not that kind of doctor) to the best of my knowledge, and neither am i, but you seem to have mentioned both of us as candidates | 21:06 |
| LjL | so i would double-check your requirements if i were you | 21:07 |
| kreyren[m] | bcs you are giving me useful info which is all i need thus why i suggested you making medicine-related thing like covid~ | 21:07 |
| de-facto | i dont have any medical background at all | 21:07 |
| ublx | i'd just put myself through a few first-aid courses if i were kreyren | 21:07 |
| kreyren[m] | i did that already it sucks | 21:07 |
| kreyren[m] | ... well it was long time ago but stilL! | 21:07 |
| Brainstorm | Updates for Cuba: +6750 cases (now 231568), +39 deaths (now 1490) since a day ago | 21:09 |
| kreyren[m] | so LjL making a medical room would be much better >.> | 21:10 |
| ublx | what country are you in, kreyren[m]? | 21:12 |
| kreyren[m] | morava~ | 21:12 |
| kreyren[m] | it's in czechia | 21:12 |
| ublx | hm | 21:12 |
| LjL | i have no overarching general interest in medicine, if you don't count bouts of hypochondriasis and morbid interest in neurological diseases | 21:12 |
| LjL | and i sometimes find it difficult enough to manage just this channel | 21:13 |
| ublx | is it possible to pay for paramedic training there, kreyren[m]? | 21:13 |
| LjL | i suggest you go into ##medicine and contribute to making it better if it seems to suck | 21:13 |
| ublx | i mean, if first-aid courses did nothing for you... | 21:13 |
| kreyren[m] | ublx: dunno i was forced through those when i was a kid though x.x | 21:13 |
| ublx | smh | 21:13 |
| ublx | you know course providers exist that give first basic first-aid course, and further courses, all the way up to paramedic? | 21:14 |
| ublx | *depending on the country, i guess. ymmv | 21:14 |
| * kreyren[m] is from family of doctors who constantly are constantly making him to learn things about medicine | 21:15 | |
| de-facto | we even have to do those at university, its mandatory | 21:15 |
| kreyren[m] | ublx: the issue is that only the university is useful as those trainings only teach generic things without any peer review and research | 21:16 |
| * kreyren[m] would also be in medschool in Q2 2020 if covid wasn't a thing | 21:17 | |
| ublx | kreyren[m]: why not get a job as an ambulance paramedic in the meantime, as valuable work experience? | 21:19 |
| ublx | it's in the ballpark | 21:19 |
| kreyren[m] | too insane doing that during pandemic x.x | 21:20 |
| ublx | and being a doctor isn't? | 21:20 |
| kreyren[m] | i just want the experience i don't want to work as one >.> | 21:20 |
| LjL | ublx, from what i gather, kreyren[m] currently only leaves his home with a gas mask | 21:21 |
| ublx | how are you going to explain in your application for med school that you did nothing to acquire relevant experience while waiting for universities to open up, or whatever other reason you have for not currently moving forward? | 21:21 |
| kreyren[m] | that's for US medschool not how that works in czechia last time i checked | 21:23 |
| LjL | kreyren[m], are you seriously saying you're planning to go to medical school and technically become a doctor only for the experience while never actually intending to practice as a doctor? | 21:24 |
| Spec_ | i'll do it, too | 21:24 |
| kreyren[m] | LjL: I recognize that i need to practice to keep my experience up to day and confident, but i didn't decide yet how while leaning towards being a surgeon and being doctor for my subordinates | 21:26 |
| kreyren[m] | *up to date | 21:27 |
| LjL | Spec_, what, go to med school for kicks? | 21:28 |
| Spec_ | yes, so i can be Dr Spec | 21:28 |
| LjL | Spec_, that would solve the nickname issue | 21:28 |
| kreyren[m] | also drugs! drugs! drugs drugs drugs | 21:29 |
| Spec_ | and sewing human flesh, good skill for life savings and bookmakings | 21:30 |
| LjL | be sure to tell your medical school that access to drugs is an important goal of obtaining a medical degree for you | 21:30 |
| kreyren[m] | xDDD | 21:30 |
| kreyren[m] | my main motivation is being able to self-diagnose and care for my subordinates while having the knowledge to participate in scientific research tbh | 21:31 |
| kreyren[m] | <Spec_ "and sewing human flesh, good ski"> also yes~ great thing i learned that when i opened my leg up while being far from civilization and on a bike without a phone | 21:32 |
| ublx | is this a language barrier thing? what is subordinates intended to mean here? | 21:32 |
| Spec_ | you don't need to "study" to learn how to self diagnose, you just need to visit webmmd | 21:32 |
| Brainstorm | Updates for Germany: +861 cases (now 3.7 million) since 23 hours ago | 21:33 |
| kreyren[m] | ublx Rather friends with benefits while using socially acceptable term for slaves who serve me on their own free will~ | 21:33 |
| kreyren[m] | Spec_: meeh | 21:34 |
| ublx | kreyren wtf | 21:34 |
| kreyren[m] | whaaat | 21:34 |
| LjL | wtf indeed | 21:36 |
| kreyren[m] | u.u | 21:36 |
| ublx | are you trying very hard to say employees without using the word employees? | 21:36 |
| kreyren[m] | nah i treat employees differently | 21:36 |
| ublx | then wtf are you talking about | 21:37 |
| kreyren[m] | u r making this weird >.> | 21:37 |
| ublx | i'm just trying to understand the narrative in which YOU are NOT weird | 21:37 |
| kreyren[m] | u.u | 21:37 |
| kreyren[m] | why would i be weird! | 21:38 |
| LjL | kreyren[m], no, you're making it weird | 21:38 |
| kreyren[m] | \>.< | 21:39 |
| LjL | some degrees of weird are probably fine and you can decide to uphold your weirdness, but don't offload it on others | 21:39 |
| kreyren[m] | since when are friends with benefits weird they even made it a law in US now >.> | 21:39 |
| LjL | calling them subordinates or slaves is pretty damned weird | 21:40 |
| LjL | you can have your kinks in private without this tone about them in this channel | 21:41 |
| kreyren[m] | the slaves wasn't my idea >.> | 21:41 |
| ublx | oh well, lets move on | 21:41 |
| kreyren[m] | aaa u r making me look like some weird person with weird addictions in sex things >.> | 21:42 |
| kreyren[m] | <ublx "oh well, lets move on"> YES | 21:42 |
| kreyren[m] | i need medkit things~ | 21:42 |
| LjL | the topic of this channel is COVID, i usually don't mind broader discussion but given how this went, if you want to make a medkit inventory, please find a place that specializes in that sort of thing | 21:43 |
| kreyren[m] | u.u | 21:43 |
| kreyren[m] | bully | 21:43 |
| LjL | or whatever is appropriate, which is probably a qualified person, but i'm unqualified to say | 21:43 |
| LjL | yes this is totally bullying you | 21:43 |
| LjL | call the teacher | 21:43 |
| kreyren[m] | fufufu | 21:44 |
| LjL | waitaminute | 21:58 |
| Brainstorm | New from r/WorldNews: worldnews: Pundits Blame Government As Iranians With Cash Go To Armenia For Vaccines → https://is.gd/Hkq9cq | 22:30 |
| Brainstorm | Updates for Israel: +388 cases (now 845767), +1 deaths (now 6435) since a day ago | 22:36 |
| de-facto | .title https://imgur.com/a/2f8Wl9j https://i.imgur.com/iGLFXHD.png "COVID Germany: Cases and Reproduction" src: https://github.com/robert-koch-institut/SARS-CoV-2-Nowcasting_und_-R-Schaetzung/blob/main/Nowcast_R_aktuell.csv | 23:26 |
| Brainstorm | de-facto: From imgur.com: COVID Germany: Cases and Reproduction - Album on Imgur | 23:26 |
| de-facto | .title https://imgur.com/a/JKyUGq8 https://i.imgur.com/XQaDGce.png "COVID Germany: Cases and Reproduction (zoomed)" src: https://github.com/robert-koch-institut/SARS-CoV-2-Nowcasting_und_-R-Schaetzung/blob/main/Nowcast_R_aktuell.csv | 23:32 |
| Brainstorm | de-facto: From imgur.com: COVID Germany: Cases and Reproduction (zoomed) - Album on Imgur | 23:32 |
| de-facto | cases rise again, exactly as predicted a few weeks ago | 23:35 |
| Brainstorm | Updates for Canada: +8 deaths (now 26427) since 21 hours ago | 23:38 |
| LjL | yes, in italy too, i'm not very surprised | 23:38 |
| de-facto | tbh sometimes i am a bit surprised what mathematical precision the pandemic is following | 23:40 |
| de-facto | meaning there is not much influence acting against its evolution, its just doing its thing | 23:40 |
| de-facto | the wave is going over EU eastwards | 23:43 |
| de-facto | i even know people "surfing" it, e.g. leaving Spain and coming here | 23:43 |
| stipa | surfing my ass, they're carrying it around | 23:46 |
| de-facto | yeah unfortunately some of them do that | 23:47 |
| stipa | yeah, it will be very popular very soon | 23:48 |
| de-facto | its always happening, people leaving areas with lockdowns and spreading it to low incidence areas | 23:48 |
| de-facto | wasnt it going through the press what exactly that was happening in London? | 23:49 |
| de-facto | at some point in time we were not allowed to travel more than 15km from location of home iirc | 23:49 |
| stipa | i guess that first vaccines should be tested in practice and then go with covid passports if vaccines actually work | 23:50 |
| de-facto | i never did leave my area since begin of 2020 i was within a radius of 10km, only for vaccination i did drive to another town once | 23:50 |
| de-facto | stipa, yes but unfortunately they do it the other way around | 23:51 |
| stipa | yeah, big mistake | 23:51 |
| de-facto | i agree, its a big mistake | 23:51 |
| stipa | well, what can you expect from those idiots | 23:51 |
| de-facto | especially because it means mobility for selected breakthrough mutants | 23:51 |
| de-facto | but yeah, somehow we will have to deal with whatever comes, in the end we have to make the best out of it | 23:52 |
| stipa | sure | 23:53 |
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