| joerg | actually both are the same authors (and study), as preprint and later in The Lancet which should give it _some_ credibility | 00:17 |
|---|---|---|
| joerg | >>Budesonide dry powder was delivered using a turbohaler at a dose of 400 μg per actuation. Participants were asked to take two inhalations twice a day until symptom resolution<< | 00:28 |
| joerg | my Budecort 200 inhaler I got ... argh so long ago it's not usable anymore since 5 years unsurprisingly has 200μg per dose. Thanks for making me look at it | 00:38 |
| Brainstorm | New from r/WorldNews: worldnews: Covid vaccine: Speech comparing NHS medics to Nazis condemned → https://is.gd/lobqNW | 01:01 |
| Brainstorm | New from r/WorldNews: worldnews: Pfizer Covid-19 Vaccine 39% Effective Against Delta → https://is.gd/UT9vXQ | 01:31 |
| * joerg just wonders how they evaluated those 39%. I guess they didn't run a double-blinded study of vaccine against placebo? | 01:45 | |
| Brainstorm | New from r/WorldNews: worldnews: Two doses of Pfizer, AstraZeneca shots effective against Delta variant → https://is.gd/jdx6BD | 01:52 |
| Brainstorm | Updates for Germany: +929 cases (now 3.8 million) since 21 hours ago | 02:09 |
| Brainstorm | Updates for France: +21885 cases (now 6.0 million), +24 deaths (now 111715) since 21 hours ago — Netherlands: +6304 cases (now 1.9 million), +5 deaths (now 17941) since 23 hours ago — Canada: +301 cases (now 1.4 million) since 23 hours ago — United Kingdom: +91 deaths (now 129288) since 21 hours ago | 02:34 |
| LjL | joerg, well see this reply to me https://old.reddit.com/r/worldnews/comments/orjjhh/covid_fauci_says_us_heading_in_wrong_direction_as/h6iwjdc/?context=3 so maybe the Israeli data are simply bad, that doesn't seem impossible | 03:21 |
| LjL | however the UK is also producing this sort of numbers, and they are not doing double-blinded studies to get them | 03:21 |
| LjL | (i mean the same type of numbers, not the same numbers) | 03:21 |
| LjL | they are getting them by comparing vaccinated people against unvaccinated people after adjusting for cohorts and other potential confounders | 03:21 |
| LjL | but then i must say about this reply | 03:22 |
| LjL | > In my opinion, there isn't enough of a difference between the normal strain and the delta strain to cause that big of a drop off in effectiveness. The two strains are relatively similar and the differences wouldn't be enough to support Israel's numbers. | 03:22 |
| LjL | if someone can brush concerns off with their "opinion" that there isn't "enough of a difference" and Delta is "similar" enough that we shouldn't have a big difference in vaccine efficacy... well, i call that wishful thinking | 03:22 |
| LjL | they said "several studies" contradicted what i provided, while providing none (could have easily linked to some UK data at least) | 03:22 |
| LjL | all that trying to respond to things is giving me is anger and tinnitus, so i'll probably be (or try to be) away from this channel for the next few days | 03:23 |
| LjL | if anyone wants someone banned, like specing and joerg yesterday, you may ask another operator, because i don't want to trade *more* of my mental health | 03:24 |
| Brainstorm | New from r/WorldNews: worldnews: Malaysia's junior doctors to go on strike over unfair policies, most deployed at Covid-19 treatment centres and hospitals → https://is.gd/b4v6V1 | 04:59 |
| joerg | just a formal note: I mused about a bot to ban certain obvious trolls. I didn't ask you or anybody else to ban anybody, I once incorrectly suggested "ban the hostmask" to specing when I actually meant "ignore" | 05:09 |
| Brainstorm | New from The Indian Express: World: Australia’s Victoria eyes Covid-19 lockdown exit as cases fall → https://is.gd/tHU1Xk | 05:09 |
| Brainstorm | New from The Indian Express: World: Germany considers restrictions for unvaccinated → https://is.gd/rLonar | 05:20 |
| -Bridgestorm- 🌏 Gempa bumi! Lindu! Earthquake! 5.9 M tremor, registered by infoBMKG, occurred 5 minutes ago (03:52:03 UTC), during daytime, Ampana, Indonesia (-0.73, 121.87), ↓10 km likely felt 250 km away (in Ampana…) by 40300 people → https://twitter.com/infoBMKG/status/1419506917785759748 (Twitter) | 05:57 | |
| Brainstorm | Updates for Thailand: +15376 cases (now 512678), +87 deaths (now 4146) since a day ago — United Kingdom: +36177 cases (now 5.7 million), +86 deaths (now 129295) since 23 hours ago — France: +18106 cases (now 6.0 million), +20 deaths (now 111717) since 22 hours ago — Netherlands: +4785 cases (now 1.9 million), +4 deaths (now 17942) since 22 hours ago | 06:06 |
| Brainstorm | New from EurekAlert!: Anticipate a resurgence of respiratory viruses in young children: Canada should anticipate a resurgence of a childhood respiratory virus as COVID-19 physical distancing measures are relaxed, authors warn in CMAJ (Canadian Medical Association Journal) https://www.cmaj.ca/lookup/doi/10.1503/cmaj.210919. → https://is.gd/eeeSYe | 06:22 |
| Brainstorm | New from r/WorldNews: worldnews: Coronavirus infections continue to fall in UK → https://is.gd/C2BMAL | 06:32 |
| Brainstorm | New from The Indian Express: World: French parliament OKs restaurant COVID pass, vaccine rules → https://is.gd/FsLI1a | 07:04 |
| Brainstorm | Updates for Pakistan: +3752 cases (now 1.0 million), +32 deaths (now 23048) since 22 hours ago — Sindh, Pakistan: +2308 cases (now 367092), +19 deaths (now 5833) since 21 hours ago — Puerto Rico, United States: +1781 cases (now 144140), +2 deaths (now 2568) since 3 days ago — Emilia-Romagna, Italy: +565 cases (now 391422), +1 deaths (now 13273) since a day ago | 07:33 |
| Brainstorm | New from The Indian Express: World: The Delta variant is the symptom of a bigger threat: Vaccine refusal → https://is.gd/qTmBED | 07:35 |
| Brainstorm | New from r/WorldNews: worldnews: France mandates vaccination passes for dining and travel → https://is.gd/rlYvmR | 08:27 |
| Brainstorm | Updates for India: +39361 cases (now 31.4 million) since 15 hours ago | 08:35 |
| foo | Anyone here strongly anti-vax? What's your logic? I'm mostly curious, haven't been jabbed, still on the fence (but have felt heavy shame from a few folks). I'm mostly just slow and live alone and for as much as I love people, I don't need to rush to get anything... I still mask up. | 08:53 |
| Brainstorm | New from Science-Based Medicine: Joe Mercola: An antivaccine quack tycoon pivots effortlessly to profit from spreading COVID-19 misinformation: Joe Mercola is a physician whose nearly quarter century of promoting quackery and antivaccine misinformation has garnered him a net worth north of $100 million. It is therefore not surprising that in the age of [... want %more?] → https://is.gd/fwIg7Q | 09:08 |
| mrdata | 'mercola takedown' would be nice | 09:21 |
| foo | mrdata: not sure what your comment is in response to, but I'd be curious to hear you unapck that more. I'm aware of dr mercola and am baffled by some of the stuff I read there. | 09:23 |
| mrdata | foo, it's re above link, https://is.gd/fwIg7Q | 09:25 |
| foo | mrdata: oh. | 09:26 |
| foo | mrdata: I know some people who love his stuff. thanks for sharing. | 09:26 |
| foo | (and I've warned them against him | 09:26 |
| mrdata | good | 09:27 |
| Brainstorm | New from The Indian Express: World: Anthony Fauci wants to make vaccines for the next pandemic before it hits → https://is.gd/METaiu | 09:28 |
| mrdata | lives are at stake; while america is caught up in this free speech movement, free speech rights do not confer the immunity people believ it does | 09:29 |
| mrdata | accusing misinfo spreaders of causing deaths seems like a good move | 09:29 |
| dTal | Free speech is one of those things that makes less sense the closer you look | 09:50 |
| dTal | the flaw in the concept is that speech is action | 09:52 |
| dTal | https://en.wikipedia.org/wiki/Speech_act | 09:52 |
| dTal | so, the unmitigated right to *say* whatever you want translates into the right to *do* whatever you want, provided you don't use your actual hands to do it | 09:53 |
| dTal | we generally agree that sentences like "There's a bitcoin wallet worth 10 thousand dollars that I'll tell you the password to if you murder my neighbor" are not protected | 09:57 |
| dTal | so in practice you have a list of speech-acts which are illegal, just like any other category of behavior | 09:58 |
| dTal | so the idea of "free speech" as some vaunted ideal contributes as little as some hypothetical "freedom to punch whatever you want (*excepting this list of items including but not limited to people, property, pets, wildlife, cadavers...)" | 10:04 |
| * earthlife[m] < https://libera.ems.host/_matrix/media/r0/download/libera.chat/33deb46ea033f3a1ce9e9dfeb94cf9f56d38fa40/message.txt > | 10:33 | |
| Brainstorm | Updates for Mizoram, India: +2307 cases (now 33452), +2 deaths (now 137) since a day ago | 10:39 |
| Brainstorm | New from WHO Euro: Tajikistan completes second round of immunization campaign against circulating poliovirus: Over 1.2 million children in Tajikistan received oral polio vaccine in the second round of the supplemental immunization campaign completed on 5 July 2021. The immunization campaign was conducted in response to the identification of circulating [... want %more?] → https://is.gd/KFKwtH | 10:50 |
| Brainstorm | Updates for N. Cyprus: +744 cases (now 10724), +3 deaths (now 39) since 6 days ago | 11:04 |
| Brainstorm | New from ProPublica: How Unemployment Insurance Fraud Exploded During the Pandemic: by Cezary Podkul ] ProPublica is a nonprofit newsroom that investigates abuses of power. Sign up to receive our biggest stories as soon as they’re published. A Bronx man allegedly received $1.5 million in just ten months. A California real estate broker raked in more [... want %more?] → https://is.gd/wPt2hk | 11:21 |
| Brainstorm | New from BMJ: Long covid—mechanisms, risk factors, and management: AbstractSince its emergence in Wuhan, China, covid-19 has spread and had a profound effect on the lives and health of people around the globe. As of 4 July 2021, more than 183 million confirmed cases... → https://is.gd/Px6pOy | 11:42 |
| Brainstorm | Updates for Germany: +923 cases (now 3.8 million) since 23 hours ago | 12:31 |
| Brainstorm | New from r/WorldNews: worldnews: Hundreds of junior doctors at state-run Malaysian hospitals staged walkouts Monday demanding better conditions as the country faces its worst coronavirus outbreak yet → https://is.gd/KwrKCd | 12:34 |
| Brainstorm | New from ECDC: Data on the daily number of new reported COVID-19 cases and deaths by EU/EEA country: The downloadable data file is updated daily and contains the latest available public data on COVID-19. Each row/entry contains the number of new cases and deaths reported per day and per country in the EU/EEA. → https://is.gd/tBASDi | 13:07 |
| Brainstorm | Updates for Nepal: +2391 cases (now 682947), +25 deaths (now 9738) since 23 hours ago | 14:00 |
| -Bridgestorm- ⭕ Gempa bumi! Lindu! Earthquake! 6.5 M tremor, registered by infoBMKG, occurred 8 minutes ago (12:09:07 UTC), with a gibbous moon, Ampana, Indonesia (-0.73, 121.92), ↓10 km likely felt 380 km away (in Ampana…) by 40300 people → https://twitter.com/infoBMKG/status/1419632106020294668 (Twitter) | 14:18 | |
| Brainstorm | Updates for Iran: +31814 cases (now 3.7 million), +322 deaths (now 89122) since a day ago — Ghana: +933 cases (now 102103), +2 deaths (now 823) since a day ago | 14:37 |
| -Bridgestorm- ⭕ Gempa bumi! Lindu! Earthquake! 6.2 M tremor, registered by AT,quakenotices, occurred 29 minutes ago (12:09:06 UTC), with a gibbous moon, Minahassa Peninsula, Sulawesi (-0.72, 121.92) ± 3 km, ↓10 km likely felt 310 km away (in Ampana…) by 40300 people → https://t.co/NgGwV01XyH (Twitter) | 14:38 | |
| Brainstorm | New from r/WorldNews: worldnews: Europe tried to boost vaccine takeup with carrots. Now some leaders are breaking out the sticks → https://is.gd/oD5F6c | 14:39 |
| Brainstorm | New from r/WorldNews: worldnews: Antivaccine videos slip through YouTube’s advertising policies, new study finds → https://is.gd/4510eh | 15:01 |
| Brainstorm | New from NPR: France Passes Law That Makes A Coronavirus Health Pass Required For Dining And Travel: The law requires a special pass to enter restaurants, trains, planes and other public venues. To get the pass, people must have proof they are vaccinated, tested negative or recovered from the virus. → https://is.gd/ObLNFR | 15:11 |
| joerg | foo: I think everybody has a right to be skeptical about (particularly the new types of) vaccines. But meanwhile you got to carefuly consider what's of higher relevance to you - the concerns about mRNA and whatever maybe valid points you may have despite so many people got vaccinated with extremely little adverse effects, or the obvious and very real risk of long covid, severe injury and death by an infection. And I don't even want to start about everybody's | 15:25 |
| joerg | responsibility for the community they live in... unless you're a canadian lumberjack or a hermit | 15:25 |
| joerg | foo: if you got questions or want to discuss your concerns, you've found the right channel | 15:28 |
| joerg | I guess you won't find many strongly anti-vax here, they either didn't like all the info or most of them pwolly got convinced by it | 15:32 |
| Brainstorm | New from StatNews: Pharma: STAT+: Pharmalittle: A race to develop Covid-19 pills is underway; Russian trolls target Pfizer vaccine → https://is.gd/Tq9EMi | 15:33 |
| qkall | joerg: thanks for fighting the good fight lol i lurk here often and y'all doing god's work | 15:33 |
| joerg | we are all constantly searching if there's anything fishy in vaccines and covid-politics, however to fix/improve anything we find. And as a result of this my guess is you won't find many vax-refusers here | 15:35 |
| joerg | qkall: thanks | 15:37 |
| joerg | Rpifan: how are you? | 15:38 |
| Rpifan | A bit better thanks | 15:38 |
| joerg | ooh glad to hear | 15:40 |
| joerg | a little factoid to cheer you up: it seems long covid is pretty much unrelated to severety of initial illness | 15:42 |
| joerg | damn, STAT+ is "paywalled" | 16:04 |
| Brainstorm | Updates for Bangladesh: +15192 cases (now 1.2 million), +247 deaths (now 19521) since 23 hours ago — Iraq: +12180 cases (now 1.6 million), +60 deaths (now 18347) since a day ago — Switzerland: +1746 cases (now 714414) since 3 days ago | 16:04 |
| Brainstorm | New from EMA: What's new: Document: EMA initiatives for acceleration of development support and evaluation procedures for COVID-19 treatments and vaccines → https://is.gd/883Sya | 16:25 |
| Brainstorm | Updates for Germany: +813 cases (now 3.8 million) since 23 hours ago | 16:29 |
| nixonix | https://twitter.com/kallmemeg/status/1418567528322945031 | 16:36 |
| nixonix | in israel, theres a line between those vaccd in jan or feb, so with their 3 dose interval it seems about 6 months and breakthroughs are increasing rapidly | 16:38 |
| Brainstorm | New from WHO Euro: WHO/Europe releases report on mechanisms for improving transparency of markets for medicines, vaccines and health products: Two years after World Health Assembly Resolution 72.8 was agreed on improving the transparency of markets for medicines, vaccines and other health products, WHO/Europe has released a report identifying and [... want %more?] → https://is.gd/OiVCE0 | 16:46 |
| nixonix | couldnt find the source for that jan feb vaccinated difference. but it was somewhere... | 16:46 |
| nixonix | https://twitter.com/Birdyword/status/1418592323831750664 | 16:48 |
| nixonix | https://twitter.com/garywfuller/status/1418630244622168065 | 16:49 |
| nixonix | 45 yo. maybe common news for those with higher prevalence in the country, but it has been rare here https://twitter.com/IIHFHockey/status/1419631809428611073 | 17:10 |
| Brainstorm | New from r/WorldNews: worldnews: France Passes Law That Makes Coronavirus Health Pass Required For Dining, Travel → https://is.gd/yAGzp4 | 17:17 |
| LjL | nixonix, https://twitter.com/DrEricDing/status/1418670502734876677 https://twitter.com/DrEricDing/status/1418673579793727489 for immunity waning in israel | 17:29 |
| nixonix | ok, ty | 17:33 |
| Brainstorm | New from Reddit (test): CoronavirusUK: 26/07/2021: The Daily Figures are delayed again today - 24,950 new cases → https://is.gd/xXMjYl | 17:38 |
| nixonix | bloomberg, about israel. some nagging screen appeared, like he didnt have enough money already https://archive.is/uc5rN | 17:43 |
| Brainstorm | New from BMJ Open: Variation in SARS-CoV-2 seroprevalence across districts, schools and classes: baseline measurements from a cohort of primary and secondary school children in Switzerland: Objectives To determine the variation in SARS-CoV-2 seroprevalence in school children and the relationship with self-reported symptoms. Design Baseline measurements [... want %more?] → https://is.gd/svbBFC | 17:59 |
| nixonix | https://twitter.com/hjelle_brian/status/1415453276007407619 | 17:59 |
| nixonix | but how about memory b-cells and t-cells, and killer t-cells? how about them, when neut abs have waned? | 18:00 |
| nixonix | and which of those is better vs 617.2 or other immune evasion variants? the two first are better with longer dose intervals (mrna vaccines at least), and the latter when the interval is shorter | 18:01 |
| nixonix | they dont know | 18:02 |
| Brainstorm | New from Reddit (test): CoronaVirus_2019_nCoV: Watch: More Long Covid Cases Seen in Kids → https://is.gd/fYvdxd | 18:09 |
| nixonix | .title https://www.theatlantic.com/science/archive/2021/07/correlates-of-protection-vaccine-immunity/619508/ | 18:09 |
| Brainstorm | nixonix: From www.theatlantic.com: COVID-19 Vaccine Success Could Be Measured With One Number - The Atlantic | 18:09 |
| LjL | only thing i remember seeing about *types* of T-cells looked at helper vs others | 18:12 |
| nixonix | https://twitter.com/itosettiMD_MBA/status/1418918792801959939 | 18:16 |
| nixonix | We saw a marked skewing towards a CD4+ T cell response with the long dosing interval, but more balanced between CD4+ and CD8+ for the short interval (Figure 4A). | 18:22 |
| nixonix | These experiments revealed that, in those who made an IFNγ response on ELISpot, infection-naïve recipients of the long dosing interval generated a higher IL2 CD4+ response to spike compared with the short dosing interval, along with higher IFNγ and TNF CD4+ responses (Figure 4B), whilst the CD8+ response was reversed with lower IFNγ response | 18:22 |
| nixonix | for the long interval | 18:22 |
| nixonix | https://www.pitch-study.org/PITCH_Dosing_Interval_23072021.pdf | 18:25 |
| nixonix | https://www.pitch-study.org/Figures_Appendix_PITCH_Dosing_interval_23072021.pdf | 18:28 |
| Brainstorm | Updates for Bahamas: +471 cases (now 14252), +10 deaths (now 284) since 3 days ago — United Kingdom: +16820 cases (now 5.7 million) since 22 hours ago | 18:33 |
| nixonix | damn confusing all these different polyfunctional and effector t-cells, and their roles | 18:41 |
| nixonix | .title https://www.cell.com/cell-reports-medicine/fulltext/S2666-3791(21)00203-2 | 18:52 |
| Brainstorm | nixonix: From www.cell.com: Home: Cell Press | 18:52 |
| nixonix | Longitudinal analysis shows durable and broad immune memory after SARS-CoV-2 infection with persisting antibody responses and memory B and T cells | 18:52 |
| nixonix | Virus-specific CD4+ and CD8+ T cells are polyfunctional and maintained with an estimated half-life of 200 days. Interestingly, CD4+ T cell responses equally target several SARS-CoV-2 proteins, whereas the CD8+ T cell responses preferentially target the nucleoprotein, highlighting the potential importance of including the nucleoprotein in future | 18:54 |
| nixonix | vaccines | 18:54 |
| Rpifan | So yea I've partially lost my sense of taste | 18:56 |
| nixonix | sars2 infection? | 19:04 |
| Rpifan | Yea | 19:09 |
| Rpifan | I lost it today when the symptoms have been improving | 19:09 |
| nixonix | if you read that last cell link, wiki page for t-cells is helpful for different t-cell types (there are plenty of them, and i think their roles arent nearly perfectly understood yet) | 19:11 |
| nixonix | vaccinated? | 19:11 |
| Rpifan | No | 19:16 |
| Rpifan | So yea I've got fluticasone | 19:16 |
| Rpifan | And I have been seeing some Dr's do. Recommend steoroids to help with covid | 19:16 |
| Rpifan | But the front staff of my doctor don't give a fuck | 19:16 |
| Rpifan | And I can't speak to my doctor directly | 19:16 |
| Rpifan | Ans the local doctors don't answer my instant callsn | 19:16 |
| Rpifan | I'll. Just have to. Do without | 19:17 |
| nixonix | while it has been widely reported that age correlates with COVID-19 disease severity, we found that age and disease severity were independent co-variates associated with the magnitude of both SARS-CoV-2-specific CD4+ T cell and humoral SARS-CoV-2 immunity, but not with the magnitude of CD8+ T cell responses | 19:18 |
| nixonix | steroids too early isnt good. only helpful when theres need for extra oxygen or so (and still some doctors give them, when symptoms get worse) | 19:19 |
| nixonix | and they might even predispose for fungal infections | 19:20 |
| nixonix | like here (doc promised steroids if symptoms get worse): 'I will prescribe you a fire-fighting stash of steroids and antibiotics in the event of you deteriorating over the weekend. I hope you won't need them unless there is a worsening in your status.' | 19:21 |
| nixonix | .title https://www.dailymail.co.uk/news/article-9821615/The-vaccine-saved-life-PIERS-MORGAN-reveals-caught-Covid-Euros-final.html | 19:21 |
| Brainstorm | nixonix: From www.dailymail.co.uk: The vaccine may well have saved my life: PIERS MORGAN reveals he caught Covid at Euros final | Daily Mail Online | 19:21 |
| nixonix | why not vaccd? | 19:22 |
| Rpifan | My fault | 19:23 |
| nixonix | you thought vaxx would be more dangerous than infection? | 19:23 |
| Rpifan | No | 19:23 |
| Rpifan | I was just scared of the side efeccts | 19:23 |
| nixonix | its very rare with mrna, just those anaphylaxes that can be taken care of, and then some myo/pericarditises, that are mostly mild | 19:25 |
| nixonix | and theres never been long term side effects from any vaccine before, so very unlikely that there would be from these either | 19:26 |
| nixonix | when theres no mechanism for those | 19:26 |
| dzho | headache, chills/shakes | 19:26 |
| dzho | fatigue | 19:26 |
| nixonix | oh yeah, and sore shoulder, i forgot those | 19:26 |
| dzho | yup | 19:26 |
| nixonix | well, if you get the evil headache, maybe try to suffer without ibu (not sure about this, but some sources say its better without, so it wouldnt affect the immune response) | 19:27 |
| dzho | I think not talking about the common and treatable, but temporary, side effects leaves more room for people to jump in with their fear uncertainty and doubt. | 19:28 |
| dzho | yeah I took acetaminophen/paracetemol and it was fine | 19:28 |
| dzho | I took too little and suffered a little bit unnecessarily but whatever. | 19:28 |
| dzho | taking that was explicitly recommended instead of ibuprofen | 19:29 |
| nixonix | now if anybody knows about vaccine breakthroughs, if theres been symptoms linked to possible brain damage (like without vaccine), eg memory, foggy etc, link me the source | 19:31 |
| nixonix | im not sure if paracetamol is more recommended than ibu. or if either actually affects the hoped immune response, might be just advice for just in case | 19:32 |
| Brainstorm | New from Reddit (test): Monday 26 July 2021 Update: submitted by /u/HippolasCage to r/CoronavirusUK → https://is.gd/CKyyre | 19:32 |
| Brainstorm | Updates for Italy: +3115 cases (now 4.3 million), +22 deaths (now 127971) since 23 hours ago | 19:36 |
| nixonix | .title https://www.scientificamerican.com/article/to-beat-covid-we-may-need-a-good-shot-in-the-nose/ | 19:36 |
| Brainstorm | nixonix: From www.scientificamerican.com: To Beat COVID, We May Need a Good Shot in the Nose - Scientific American | 19:36 |
| nixonix | .title https://science.sciencemag.org/content/373/6553/397 | 19:36 |
| Brainstorm | nixonix: From science.sciencemag.org: Scent of a vaccine | Science | 19:37 |
| nixonix | i think we need some parts of n-protein used in vaccine. if these s only vaccines dont protect from severe symptoms long enough | 19:39 |
| nixonix | check how few reinfections in uk, and compare it to israels vaccine breakthrough numbers https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/1005517/Technical_Briefing_19.pdf | 19:45 |
| nixonix | page 36 | 19:46 |
| pwr22 | Anyone know why confirmed infections in the UK have seemingly come down? | 19:48 |
| nixonix | severe symptoms or different long term damage, like brains, telomeres, b-cell islets etc | 19:48 |
| nixonix | i linked couple of twitter threads above, about why uk cases came down. this is the best guess i found: https://twitter.com/garywfuller/status/1418630244622168065 | 19:49 |
| nixonix | but heres discussion and ideas: https://twitter.com/Birdyword/status/1418592323831750664 | 19:50 |
| Brainstorm | New from r/WorldNews: worldnews: India's excess deaths during pandemic up to 4.9 mln, study shows → https://is.gd/iPzIIr | 19:53 |
| nixonix | but uk has high vaccine prevalence among adults. and high prevalence of infections, and immunity from those | 19:53 |
| nixonix | and for younger folks theres larger share of those with 1st dose yet, but then those also have higher prevalence of infections. so they might be on the immunity threshold already, when you add other factors like summer, some people still careful and some existing control measures | 19:55 |
| nixonix | here's cdc's forecast for usa: https://twitter.com/ScottGottliebMD/status/1418938128786595840 | 19:58 |
| nixonix | NHS England said one-third of 18- to 29-year-olds had still not had at least one dose of the vaccine – a figure that falls to one in 10 for the whole adult population | 20:01 |
| nixonix | .title https://www.theguardian.com/world/2021/jul/25/seriously-ill-young-people-in-current-covid-admissions-expert-warns | 20:03 |
| Brainstorm | nixonix: From www.theguardian.com: Doctors warn over increasing number of young people with Covid in ICU | Coronavirus | The Guardian | 20:03 |
| Brainstorm | New from Gazzetta Ufficiale italiana: MINISTERO DELLA SALUTE - ORDINANZA 24 luglio 2021: Ulteriori misure urgenti in materia di contenimento e gestionedell'emergenza epidemiologica da COVID-19 in occasione delpre-vertice delle Nazioni Unite sui sistemi alimentari in programma aRoma dal 26 al 28 luglio 2021. (21A04615) → https://is.gd/mUMCUY | 20:03 |
| nixonix | .title https://www.bbc.com/news/blogs-trending-57928647 | 20:09 |
| Brainstorm | nixonix: From www.bbc.com: The YouTubers who blew the whistle on an anti-vax plot - BBC News | 20:09 |
| nixonix | An influencer marketing agency called Fazze offered to pay him to promote what it said was leaked information that suggested the death rate among people who had the Pfizer vaccine was almost three times that of the AstraZeneca jab. The information provided wasn't true. | 20:09 |
| nixonix | Fazze is a part of AdNow, which is a digital marketing company, registered in both Russia and the UK. The BBC has made multiple attempts to contact AdNow by phone, email and even a letter couriered to their Moscow headquarters, but they have not responded. | 20:09 |
| nixonix | russians spreaded that kind of stuff about AZ last fall, when it looked promising. but then changed their target to mrna vaccines | 20:11 |
| nixonix | .title https://www.reuters.com/world/europe/italys-draghi-dismisses-chinas-covid-vaccine-casts-doubt-sputnik-2021-06-25/ | 20:13 |
| Brainstorm | nixonix: From www.reuters.com: Italy's Draghi dismisses China's COVID vaccine, casts doubt on Sputnik | Reuters | 20:13 |
| nixonix | .title https://www.reuters.com/world/the-great-reboot/exclusive-european-efforts-assess-russias-sputnik-v-vaccine-stymied-by-data-gaps-2021-07-13/ | 20:13 |
| Brainstorm | nixonix: From www.reuters.com: EXCLUSIVE European efforts to assess Russia’s Sputnik V vaccine stymied by data gaps | Reuters | 20:13 |
| -RSSBot[LjLmatrix- Feed: Green Pass: come riconoscere facilmente quello autentico ( https://www.governo.it/it/articolo/green-pass-come-riconoscere-facilmente-quello-autentico/17527 ) | 20:13 | |
| Brainstorm | New from WebMD: Survey: Parents Split on COVID Vaccination for Kids Under 12: In this June survey of more than 2,000 parents with at least one child between 3 and 18 years of age, 49% parents with kids aged 3 to 11 said they would likely get their child vaccinated, while 51% said they were unlikely to do so. → https://is.gd/NOICSW | 20:24 |
| nixonix | .title https://www.nytimes.com/2021/06/26/health/covid-vaccine-teens-consent.html | 20:33 |
| Brainstorm | nixonix: From www.nytimes.com: As Parents Forbid Covid Shots, Defiant Teenagers Seek Ways to Get Them - The New York Times | 20:33 |
| Brainstorm | Updates for Spain: +61625 cases (now 4.3 million) since 3 days ago | 21:03 |
| Brainstorm | New from CIDRAP: News Scan for Jul 26, 2021: COVID-19 in college roommates COVID vaccine for kidney recipients Interspecies CWD spread Saudi MERS case More H5N6 avian flu cases in China → https://is.gd/2GPRI7 | 21:58 |
| Brainstorm | New from WebMD: Most Unvaccinated Americans Want to Stay That Way: Poll: A new survey reveals eight in 10 American adults who haven't received a COVID-19 shot say they are unlikely to get one. → https://is.gd/DfYtyL | 22:19 |
| imaginary | shocking | 22:25 |
| nixonix | did they ask them if they want sars2 infection? | 22:41 |
| Brainstorm | Updates for Turkey: +30423 cases (now 5.6 million), +118 deaths (now 50997) since 22 hours ago | 22:42 |
| nixonix | some people want infections. i think it was called pozzing or something | 22:43 |
| LjL | nixonix, i don't think that's the same phenomenon here... | 22:47 |
| LjL | but yes, i'm aware | 22:47 |
| nixonix | ima write only jokes here from now on. they get more response | 22:54 |
| nixonix | topol had a daily mail link in his tweet. he knows quality medias too. lemme see if i can find it | 22:56 |
| LjL | nixonix, you need more de-facto for more responses | 22:57 |
| LjL | <Brainstorm> New from r/WorldNews: worldnews: Vaccine maker BioNTech to use mRNA tech to target malaria → https://is.gd/7c2YNB | 22:58 |
| nixonix | https://twitter.com/EricTopol/status/1416047347641905153 | 22:58 |
| nixonix | .title https://www.wsj.com/articles/covid-19-immunity-wanes-but-third-shot-still-rarely-needed-biontech-ceo-says-11627211359 https://archive.is/Zf7ZX | 22:59 |
| Brainstorm | nixonix: From www.wsj.com: Covid-19 Immunity Wanes, but Third Shot Still Rarely Needed, BioNTech CEO Says - WSJ | 22:59 |
| LjL | biontech ceo contradicts pfizer?! | 23:07 |
| LjL | well he also does say "“The antibody titers are going down,” Dr. Sahin said, referring to the unit of measurement for antibodies against the virus. “The vaccine protection against the new variant is considerably lower.”" which doesn't sound great | 23:08 |
| LjL | i can't read the whole WSJ article though | 23:10 |
| bin | https://archive.is/Zf7ZX | 23:13 |
| bin | LjL: ^^ | 23:13 |
| LjL | ah right sorry | 23:14 |
| bin | np | 23:14 |
| bin | i didnt see it at first and went to go archive it | 23:14 |
| nixonix | .title https://www.nature.com/articles/s41586-021-03817-4 | 23:19 |
| Brainstorm | nixonix: From www.nature.com: Broad sarbecovirus neutralization by a human monoclonal antibody | Nature | 23:19 |
| nixonix | they suggest using RBD only for vaccines, instead of whole S, to promote that type of antibodies. why not two proteins then, RBD and (modified) S | 23:20 |
| foo | joerg: a bit delayed... | 23:21 |
| foo | joerg: but thank you. | 23:21 |
| foo | joerg: and FYI, I isolate fairly well - work remotely, camp and live out of my truck, sometimes weeks a month. If I am with people we're outdoors distanced or I'm indoors masked like 10ft from them | 23:21 |
| foo | joerg: I don't have a huge rush to get it. I do get the value of doing it for the community to minimize variants. | 23:21 |
| foo | I have had family members not let me into their homes because I'm not vaccinated (and whether or not I'm transparent about not seeing anyone for 2 weeks prior seems irrelevant... which is a bit irrational IMO) | 23:22 |
| Rpifan | Well now that I've had covid idk what else to do | 23:22 |
| Rpifan | First wait a bit to make sure I survivive | 23:22 |
| Rpifan | But then am I done | 23:23 |
| Rpifan | Is that it | 23:23 |
| foo | Rpifan: when did you get it? | 23:23 |
| Rpifan | Thursday | 23:23 |
| foo | Rpifan: ah, godspeed. | 23:23 |
| nixonix | or like with that anorther vaccine that used 6 peptides attached to another protein, but using only those few selected conserved regions of RBD like in that paper. interesting that they found region from RBD that doesnt mutate a lot | 23:23 |
| Rpifan | It's OK I've actually recovered quite a bit today | 23:23 |
| Rpifan | First day I've been able to move | 23:24 |
| foo | Is there any data on who gets long-covid? | 23:24 |
| Rpifan | My sense of taste went out today | 23:25 |
| bin | Rpifan: wait 90 days afteryouve fuully recovered and then get the vaccine | 23:33 |
| Rpifan | Are any none Mrna vaccine gonna be deployed soon? | 23:37 |
| nixonix | novavax, but prob not this year | 23:40 |
| nixonix | whats wrong with mrna? | 23:40 |
| Brainstorm | New from r/WorldNews: worldnews: Pfizer and Moderna to expand size of vaccine studies in 5- to 11-year-olds → https://is.gd/dAjWnZ | 23:42 |
| Brainstorm | New from r/WorldNews: worldnews: New 'medical freedom' law outlaws requiring COVID-19 vaccine to access public spaces → https://is.gd/e48H6x | 23:52 |
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