nixonix | 2 hours earlier times. when actually our in our health care institute the party that wants to let it rip now has won, and politicians think thats prob a good idea, we just dont tell it to people and let it rip anyway | 00:00 |
---|---|---|
Brainstorm | New from Ars Technica: Science: Record-setting COVID surge in Florida spurs pro-mask uprising against DeSantis → https://is.gd/pIeP0D | 00:01 |
nixonix | did i link whats happening in florida, who have similar vacc coverage than eu average? and lots more immunity from infections than our 5% or so. i think i did | 00:02 |
nixonix | brainstorm is a mind reader | 00:02 |
nixonix | heres some more, florida https://twitter.com/DrEricDing/status/1422569185050251268 | 00:04 |
de-facto | hmm looks bad, but if the cites from DeSantis are correct i am not surprised | 00:06 |
himesama | are any of the let it rippers aware of lc? | 00:07 |
himesama | urgent question: the outside of masks was said to be where virions have been found in large numbers. i put a used half faceplate with its p100 cartridges in a ziploc bag (which means, maybe, it gets all around to the face part also?). how many days to let it sit to decontaminate? 2-3 days enough? cannot always clean it. | 00:09 |
de-facto | it can stay infectious for weeks on certain surfaces | 00:11 |
de-facto | it decays exponentially though, decay constants depending on circumstances | 00:11 |
de-facto | btw such masks should be cleaned with the proper liquid on regular basis anyhow, i think for my silicon half mask they would sell me Isopropanol, but it depends on the type of plastic in use, some may loose their softness by the wrong sanitizing agent | 00:13 |
de-facto | i think i know some people that used isoprop on thermoplastic and it became less soft | 00:14 |
de-facto | there are many studies about properly sanitizing masks, also with ozone, UV-C, etc | 00:15 |
de-facto | all depends on the materials and assumed contamination amounts | 00:15 |
de-facto | i would say 2-3 days are not a guarantee that it is decontaminated | 00:16 |
nixonix | and half-"life" is increased a lot if there are 1000x viable virions now? | 00:18 |
de-facto | but it depends on the dose: assuming a certain (fixed) dose is required to start an infection it depends on the contamination dose of the mask how long the exponential decay needs to come below that infectious threshold | 00:18 |
de-facto | 1000.-fold ~ 10 half lifes | 00:19 |
nixonix | "wish we had 2 virologists, 2 public health whatevers, and 2 epidemiologists here" | 00:19 |
himesama | the face part is silicone. the harness is softish plastic and various materials. the cartridges are hard plastic. the valves are soft floppy material. | 00:19 |
nixonix | and we dont? in two armchairs. immunologists too... | 00:19 |
LjL | 1000x in a swab probably doesn't automatically mean there will be 1000x in a square meter of air | 00:19 |
nixonix | yeah, we can hope. and viable virions maybe only 10-100x perhas | 00:20 |
nixonix | ps | 00:20 |
nixonix | i like to read about australia, just dm articles mostly. its strangely fascinating, kind of the sci-fi sub-genre alternate history | 00:22 |
himesama | i assume silicone is not affected by iso (if i am able to do that which might nmot) but hte other parts idk | 00:22 |
de-facto | LjL, hmm why not? just not that its 1000-fold as infectious (if possibly less percentage of them are intact) | 00:22 |
himesama | the bag has been in high heat every day above 90f | 00:23 |
de-facto | most manufacturers got cleaning instructions for their product | 00:23 |
de-facto | also maintenance and control | 00:24 |
himesama | it has a proprietary cleaning solution that it recommends | 00:25 |
himesama | and was likely many years ago decided on | 00:26 |
de-facto | so try to find out the ingredients of that, in order to see material compatibility | 00:26 |
de-facto | then if it contains some alcohol, bingo | 00:26 |
nixonix | i wonder if ct bought that 300 dollar mask he was considering | 00:27 |
himesama | well i guess whatever i do i try removing cartridges and then cleaning and then putting new cartridges in | 00:28 |
de-facto | otherwise using some hot water with soap also should inactivate quite some of the virions (and wash them away) | 00:28 |
de-facto | should be quite compatible with most plastic materials, without weakening its structural integrity | 00:28 |
de-facto | hmm maybe thats what i would do, twice | 00:29 |
de-facto | but of course not too hot, since thermoplasts got their name for a reason | 00:31 |
nixonix | https://twitter.com/itosettiMD_MBA/status/1423407722452619266 | 00:31 |
Brainstorm | Updates for Bulgaria: +500 cases (now 426932), +14 deaths (now 18243) since 23 hours ago — Fr. Polynesia: +489 cases (now 21805), +1 deaths (now 155) since 21 hours ago | 00:32 |
Brainstorm | New from The Lancet (Online): [Viewpoint] What are the obligations of pharmaceutical companies in a global health emergency?: During a global health emergency, everyone is morally required to help to combat the disease. With approximately 8000–10 000 people dying every day from COVID-19, as of writing, only rapid and globally distributed [... want %more?] → https://is.gd/SSbAt8 | 00:33 |
de-facto | would also try to decontaminate the different assumed contamination levels separately | 00:33 |
de-facto | e.g. the parts of the mask with low assumed contamination level not together with the parts that may have been highly contaminated | 00:34 |
nixonix | howcome so many partly vaccinated, with their 3 week dose interval? | 00:35 |
-RSSBot[LjLmatrix- Feed: Nota della Presidenza del Consiglio ( https://www.governo.it/it/articolo/nota-della-presidenza-del-consiglio/17594 ) | 00:37 | |
nixonix | kids https://twitter.com/deborahblum/status/1423397424375140354 | 00:38 |
nixonix | waning https://twitter.com/RanIsraeli/status/1423322271503028228 | 00:41 |
Brainstorm | New from r/WorldNews: worldnews: Japan's population drops by record number to 126.65 million amid pandemic → https://is.gd/y46hE9 | 00:43 |
nixonix | maybe because they were normalized for size of the group of 1 dosers... | 00:51 |
nixonix | and age | 00:51 |
nixonix | As of Tuesday, Tennessee reported six deaths among children 10 and younger and five deaths among people 11 to 20. | 00:54 |
nixonix | idk if from the same day or from longer period, though | 00:54 |
nixonix | https://twitter.com/Cleavon_MD/status/1423365729206902784 | 00:56 |
LjL | Italy decided for mandatory green pass (aside from in bars, restaurants, events) also for school personnel, university students, and long-hault transport (anything except local and regional transport) | 01:02 |
LjL | i wonder if there's enough people to do the checks | 01:03 |
himesama | so wht is a good amount of time? does that include plastic? (or do we know)--- 15:11 <de-facto> it can stay infectious for weeks on certain surfaces | 01:04 |
nixonix | how about international transport? | 01:05 |
nixonix | trucks from cross the border. and why not ship crews | 01:06 |
nixonix | on pastic virions stayed longer than on paper or cardbord. metal was shortest, esp copper (from memory, over year ago, hope im right... | 01:07 |
nixonix | board | 01:07 |
nixonix | and plastic. damn | 01:07 |
nixonix | but you should try to find studies on indian variants virions | 01:08 |
LjL | i'm taking international transport for granted, that's coordinated across the EU | 01:10 |
LjL | rapid tests will cost €15 by the way (€8 for kids up to some age), seems like a lot, but i guess they can't be compared to the "supermarket ones", since they're done by pharmacies and you get a green pass for them | 01:11 |
specing | LjL: no need to do checks, just make monstrous fines for that once-in-a-decade when they actually find you | 01:11 |
LjL | but don't Germany and Greece give one or two of this type of tests for free per week? | 01:11 |
LjL | specing, yeah that's our public transport has always worked, see how well it has managed to make people actually buy tickets | 01:12 |
specing | afain in germany the tests are free for all | 01:12 |
LjL | my high school friends' standard procedure was just to run faster than ticket collectors | 01:12 |
specing | here they are free for everyone with gov insurance and will cease being free at end of this month | 01:12 |
LjL | the fact the tests aren't free basically makes vaccination mandatory for school workers. who will decide to take a test every 48 hours instead? | 01:13 |
nixonix | havent read much about this, but just read a finnish woman telling everything takes 3 times longer, started to forget names etc | 01:13 |
nixonix | .title https://www.nature.com/articles/s41380-021-01148-4 | 01:13 |
Brainstorm | nixonix: From www.nature.com: Chronic post-COVID-19 syndrome and chronic fatigue syndrome: Is there a role for extracorporeal apheresis? | Molecular Psychiatry | 01:13 |
specing | LjL: here the ticket collectors have no right to ID nor apprehend you, so you can just wave them goodbye as you exist at the next stations | 01:14 |
LjL | for... what | 01:14 |
specing | -s | 01:14 |
specing | LjL: yes | 01:14 |
specing | governments are taking the slow-boiled-frog approach | 01:14 |
nixonix | aka ME/CFS aka post-infectious myalgic encephalomyelitis/chronic fatigue syndrome | 01:14 |
specing | since as you said, mandatory vaccinations would cause riots | 01:14 |
dTal | why are tests for kids cheaper? surely it costs the same to test them. Is it a subsidy? Why not subsidize the lot? | 01:14 |
LjL | certainly subsidized | 01:15 |
LjL | i dunno "why". transport tickets are also cheaper for kids, why? | 01:15 |
dTal | but they're not subsidized, they're ridiculously overpriced | 01:15 |
dTal | my government literally hands them out free | 01:16 |
dTal | I can get 7 a day in the mail | 01:16 |
LjL | if it were my decision, i'd retrospectively justify it as "vaccinating kids is more controversial given the skewed risk/benefit ratio and discoveries of cardiac side effects on younger, so it's more reasonable to just have them tested, so it should cost less" | 01:16 |
dTal | maybe I should sell them to you guys on ebay! | 01:16 |
LjL | dTal, in the mail? those are self-administered test though... can't get a green pass from those | 01:16 |
dTal | oh so what you're paying for is the wages of test administrators | 01:17 |
LjL | maybe | 01:17 |
LjL | not sure the tests are quite the same either | 01:17 |
dTal | these are lateral flow tests? | 01:17 |
dTal | because "green pass" for lateral flow is stupid | 01:17 |
LjL | they are not PCR so... presumably yes? | 01:17 |
LjL | well green pass from PCR is not logistically possible | 01:18 |
dTal | no indeed | 01:18 |
LjL | green pass from a test is valid for 48 hours, it takes more than 48 hours to get a test result | 01:18 |
dTal | thus throwing the "green pass" concept into question | 01:18 |
LjL | well it's been into question from the start | 01:18 |
LjL | but, here, we don't tolerate even the slightest hint of green pass skepticism | 01:18 |
dTal | a lateral flow "green pass", if valid at all, should only be valid for a few hours | 01:19 |
LjL | *cough* | 01:19 |
dTal | 48 hours is ridiculous | 01:19 |
LjL | i'm not sure why you make it a matter of hours... they're bad because they have false negatives, not because they have a lower predictive time | 01:19 |
dTal | you can pass a lateral flow and 48 hours later be coughing like mad | 01:20 |
dTal | they're bad because they cannot detect low viral load | 01:20 |
dTal | so they do not catch early stage infections | 01:21 |
dTal | so a negatuve lateral flow, at best, means you have a low viral load | 01:21 |
dTal | which does offer some safety to those around you | 01:21 |
nixonix | arent there riots in france anyway, whatever they decide | 01:22 |
dTal | but not for 48 hours! exponential viral growth means that a "low" viral load at t=0 tells you almost nothing about the range of viral loads possible at t=48h | 01:22 |
LjL | nixonix, i think it's safe to say that, no matter hwat happens, there are riots in france | 01:25 |
LjL | meanwhile Punto Informatico is an idiot again | 01:25 |
LjL | this time they announced a "bug" in the italian green pass verification app | 01:25 |
LjL | someone filed a bug saying if you change the device's time/date, you can make invalid passes look valid | 01:26 |
LjL | DUH | 01:26 |
LjL | except that's absolutely irrelevant, because the validity is only shown to the owner of the device making the check | 01:26 |
LjL | and Punto Informatico has yelled at people who "didn't understand" how the green pass worked enough that they should not publish crap like this | 01:26 |
LjL | if i'm e.g. a restaurant manager and want to cheat by considering your invalid green pass valid, the easiest way to do that is to scan your pass, see the red "INVALID" result on my screen, and yet say "that's fine, please enter!" | 01:27 |
LjL | the app works offline, the result of the scan isn't shown to anybody else, so it's not very hard to understand this "bug" is bugless | 01:27 |
nixonix | well, they are planning vax or negative test results (which some politicians are requiring to be free) in finland, for bars and events, that could be ready in october... and now you are telling negative results from rapid tests arent worth a shit after couple of hours | 01:30 |
nixonix | so basically there will be a farce here later in the fall | 01:30 |
nixonix | but if you want to make a lot of money, sell them those tests before they notice | 01:33 |
Brainstorm | New from r/WorldNews: worldnews: Russian Disinformation Targets Vaccines and the Biden Administration → https://is.gd/znDlVo | 01:36 |
nixonix | https://twitter.com/K_Sheldrick/status/1423120691541340168 | 01:38 |
LjL | is it ethical to make fun of the idiotic covid-related shit someone is saying on a different channel? | 01:39 |
LjL | i guess the answer is maybe | 01:39 |
nixonix | im bad in ethics. quote? | 01:40 |
LjL | <Joanna> I have asthma and don’t enjoy suffocating <Joanna> If I go into a store and someone starts yapping about masks I do a quick about face and take my money elsewhere. <Joanna> jeaye: you know what’s really funny is on the train when a masker starts coughing and a nearby masker jumps up and runs away in terror to another part of train :) <Joanna> But they are both wearing masks so they should feel safe... <izak> lts wear our mask because | 01:42 |
LjL | it is safer than nothing. <Joanna> izak: it’s about as safe as using a chain link fence as a mosquito net :) | 01:42 |
LjL | and i interjected with | 01:42 |
LjL | <LjL> no, because masks are not full protection by any means | 01:42 |
LjL | <LjL> if you think they fully protect you, you're a moron | 01:42 |
LjL | <LjL> if you think they don't protect you at all, you're a moron | 01:42 |
nixonix | i was thinking, those russian disinformation campaigns might have hurt their own vaccinations. not sure if they have, since very low percentage of russians knows english (according to wikipedia) | 01:45 |
nixonix | well, maybe they know more german, italy, french etc and follow their medias instead of anglo (but i doubt) | 01:47 |
nixonix | italian | 01:48 |
nixonix | lingua italiana | 01:48 |
LjL | i was about to mock you in finnish about it | 01:48 |
nixonix | those are hard for me | 01:48 |
LjL | but too bad, you preempted me before i could figure out how to say "isn't" | 01:48 |
LjL | suomi on maa ja kieli | 01:48 |
LjL | italy ei | 01:49 |
nixonix | k later | 01:50 |
LjL | note to self: don't mock nixonix in finnish | 01:53 |
Brainstorm | Updates for Ivory Coast: +243 cases (now 50893), +4 deaths (now 338) since 22 hours ago — Canada: +508 cases (now 1.4 million) since 23 hours ago | 01:59 |
Brainstorm | Updates for France: +20962 cases (now 6.3 million), +41 deaths (now 112173) since 21 hours ago — Netherlands: +2450 cases (now 1.9 million), +8 deaths (now 17991) since 21 hours ago — United Kingdom: +74 deaths (now 130193) since 21 hours ago | 02:36 |
himesama | "The Alliance for Securing Democracy is a bipartisan transatlantic national security advocacy group formed in July 2017 with the stated aim of countering efforts by Russia to undermine democratic institutions in the United States and Europe. As of 2021, it had expanded to combating China's United Front Work Department. The organization is chaired and run primarily by former senior United States intelligence and Stat | 02:37 |
himesama | e Department officials." | 02:37 |
Brainstorm | New from NPR: CNN Fires Three Employees For Coming To Work Unvaccinated: The memo was obtained by The Associated Press after its contents were first tweeted by CNN media reporter Oliver Darcy. CNN offered no details on the firings, or where the employees were based. → https://is.gd/VSkCjD | 02:39 |
Brainstorm | Updates for Vietnam: +7047 cases (now 185057), +393 deaths (now 2720) since 21 hours ago | 03:01 |
himesama | i can't make sense of this but https://www.dhs.gov/science-and-technology/sars-calculator | 03:17 |
himesama | and also they have a master question list which has lots of facts but i can't seem to find the most recent version again | 03:17 |
himesama | i have it in my evince but my evince is behaving strangely not allowing me to go to top of page | 03:18 |
Brainstorm | New from r/WorldNews: worldnews: New COVID-19 outbreaks in China raise doubts about 2022 Winter Olympics in Beijing → https://is.gd/83U10x | 03:21 |
himesama | https://www.dhs.gov/sites/default/files/publications/mql_sars-cov-2_-_cleared_for_public_release_20210713.pdf | 03:21 |
himesama | which is safer nose breathing or mouth breathing/ | 03:27 |
himesama | is this true? "Transmission occurs primarily through respiratory droplets produced by talking, coughing and sneezing." | 03:29 |
Brainstorm | Updates for Guadeloupe: +2696 cases (now 23821) since 2 days ago | 03:38 |
Brainstorm | New from r/WorldNews: worldnews: Vaccine monopolies make cost of vaccinating the world against COVID at least 5 times more expensive than it could be → https://is.gd/4PrJcb | 03:42 |
Brainstorm | New from r/WorldNews: worldnews: St. Vincent Prime Minister reportedly hospitalized after being attacked and “struck in the head” by anti-vaccine protesters → https://is.gd/ertU1Y | 03:53 |
Brainstorm | Updates for Sint Maarten: +43 cases (now 2891) since a day ago | 04:40 |
Brainstorm | Updates for France: +20267 cases (now 6.3 million), +42 deaths (now 112186) since 20 hours ago — United Kingdom: +22425 cases (now 6.0 million), +65 deaths (now 130215) since 20 hours ago — Netherlands: +2542 cases (now 1.9 million), +8 deaths (now 17993) since 20 hours ago — Canada: +1241 cases (now 1.4 million) since 20 hours ago | 05:05 |
Brainstorm | New from r/WorldNews: worldnews: News-Medical.Net: Two monoclonal antibodies broadly neutralize SARS-CoV-2 variants of concern. → https://is.gd/34J0Y1 | 05:07 |
Brainstorm | New from r/WorldNews: worldnews: Fauci: New, Resistant Variants Will Happen If Vaccinations Don’t Rise → https://is.gd/cQQ1Ma | 05:17 |
Brainstorm | Updates for Thailand: +21379 cases (now 714684), +191 deaths (now 5854) since 21 hours ago | 05:30 |
Brainstorm | New from The Indian Express: World: US Covid-19 cases reach six-month high, Florida grapples with surge → https://is.gd/B8Ln1U | 06:31 |
Brainstorm | New from The Indian Express: World: CNN fires three employees for coming to work unvaccinated → https://is.gd/iI8Pgn | 06:53 |
Brainstorm | Updates for Antigua and Barb.: +9 cases (now 1320) since a day ago | 07:10 |
Brainstorm | New from The Indian Express: World: China seeks to control COVID-19 flare-up → https://is.gd/sb33IE | 07:24 |
Brainstorm | Updates for Mexico: +21569 cases (now 2.9 million), +618 deaths (now 243165) since 23 hours ago — Tokyo, Japan: +5042 cases (now 236206), +1 deaths (now 2302) since 23 hours ago — Kansas, United States: +4187 cases (now 338312) since 23 hours ago — New York, United States: +3536 cases (now 2.2 million) since 23 hours ago | 07:34 |
alibabaii[m] | hi | 07:35 |
Brainstorm | Updates for Uzbekistan: +974 cases (now 134826) since 22 hours ago — Belgium: +1973 cases (now 1.1 million), +6 deaths (now 25264) since a day ago | 07:59 |
Brainstorm | Updates for India: +44643 cases (now 31.9 million), +450 deaths (now 426610) since 15 hours ago | 08:37 |
Brainstorm | New from The Indian Express: World: China sees highest daily coronavirus cases in current outbreak → https://is.gd/HlFfnt | 08:38 |
Brainstorm | New from r/Coronavirus: Daily Discussion Thread | August 06, 2021: Please refer to our Wiki for more information on COVID-19 and our sub. You can find answers to frequently asked questions in our FAQ , where there is valuable information such as our: → https://is.gd/O02iui | 09:09 |
Brainstorm | New from The Indian Express: World: S.African study shows J&J vaccine protects against death, co-lead investigator says → https://is.gd/iFX1Jh | 09:30 |
Brainstorm | New from Virological.org: Latest topics: The molecular clock of variants of concern: The emergence of SARS-CoV-2 variants of concern is driven by episodic acceleration of the genomic rate of molecular evolution John Tay, Ashleigh F. Porter, Wytamma Wirth, and Sebastian Duchene*. Peter Doherty Institute for Infection and Immunity, University of [... want %more?] → https://is.gd/qTGtuo | 10:13 |
Brainstorm | New from The Indian Express: World: China pledges 2 billion vaccines globally through year’s end → https://is.gd/3JWxuE | 10:24 |
Brainstorm | Updates for Lithuania: +777 cases (now 285209) since a day ago | 10:41 |
Brainstorm | New from EMA: Human medicine assessment reports: (news): Human medicines European public assessment report (EPAR): Comirnaty, COVID-19 mRNA vaccine (nucleoside-modified), COVID-19 virus infection, Date of authorisation: 21/12/2020, Revision: 10, Status: Authorised → https://is.gd/golaYG | 10:45 |
Brainstorm | Updates for Philippines: +10529 cases (now 1.6 million), +246 deaths (now 28673) since a day ago — Germany: +3637 cases (now 3.8 million) since 23 hours ago | 11:06 |
Brainstorm | New from r/WorldNews: worldnews: Top court rules France's Covid-19 'health pass' complies with constitution → https://is.gd/C2OQbv | 11:58 |
Brainstorm | Updates for Guinea: +289 cases (now 26477), +5 deaths (now 243) since a day ago | 12:08 |
Brainstorm | New from ScienceNews: What science tells us about reducing coronavirus spread from wind instruments: Performers struggled to find evidence that would free them from musical lockdown, so they partnered with researchers to get some answers. → https://is.gd/mFISY9 | 12:09 |
Brainstorm | New from The Indian Express: World: Japan COVID cases hit 1 million as infections spread beyond Tokyo → https://is.gd/7DDqUh | 12:41 |
-RSSBot[LjLmatrix- Feed: Il saluto del Presidente del Consiglio Mario Draghi prima della pausa estiva ( https://www.governo.it/it/articolo/il-saluto-del-presidente-del-consiglio-mario-draghi-prima-della-pausa-estiva/17597 ) | 12:52 | |
Brainstorm | New from Politico: Aid and development: UK’s COP26 president criticized for traveling without quarantine → https://is.gd/lQxTKt | 13:23 |
Brainstorm | Updates for Malaysia: +20889 cases (now 1.2 million), +160 deaths (now 10179) since a day ago | 13:35 |
Brainstorm | Updates for Nepal: +2430 cases (now 710509), +25 deaths (now 10019) since a day ago — Switzerland: +1167 cases (now 723968) since 23 hours ago | 14:37 |
Brainstorm | New from r/Coronavirus: Coronavirus: United Airlines will require employees to be vaccinated against the coronavirus. → https://is.gd/6eGTfy | 14:58 |
Brainstorm | Updates for Azerbaijan: +1242 cases (now 349316), +8 deaths (now 5051) since 18 hours ago | 15:02 |
Brainstorm | New from Contagion Live: This Week in COVID-19 News: Is a Booster Dose Coming?: With the US federal government health agencies discussing plans for a booster dose for Americans and WHO’s call for a moratorium on these shots, a tale of two vaccine strategies is emerging. → https://is.gd/y0OyGy | 15:08 |
Brainstorm | New from Contagion Live: Recommendations for HIV Screening: Recommendations for primary care physicians to help properly identify patients who should be tested for HIV, and an overview of available screening tests. → https://is.gd/loeOmU | 15:19 |
Brainstorm | Updates for Belarus: +1295 cases (now 451740), +10 deaths (now 3513) since a day ago | 15:39 |
Brainstorm | New from StatNews: Pharma: STAT+: Pharmalittle: FDA expects to have Covid booster plan by early September; feds halt Novavax vaccine funding → https://is.gd/M07Xoy | 15:51 |
Brainstorm | Updates for Bangladesh: +12606 cases (now 1.3 million), +248 deaths (now 22150) since a day ago | 16:04 |
Brainstorm | New from r/WorldNews: worldnews: Intel agencies scour reams of genetic data from Wuhan lab in Covid origins hunt → https://is.gd/P3HjBr | 16:23 |
Brainstorm | New from r/WorldNews: worldnews: United Airlines will require all U.S. employees to get Covid vaccines, a first for domestic carriers → https://is.gd/kM4cko | 16:33 |
Brainstorm | New from NPR: California Will Require Vaccines For Workers In Health Care Facilities: Workers in health care facilities will be required to provide proof that they have been fully vaccinated against COVID-19, with exemptions only for religious or valid medical reasons. → https://is.gd/ayiCkc | 16:55 |
Brainstorm | New from StatNews: As HIMSS approaches, plans for health tech’s biggest gathering are clashing with a need for caution: HIMSS was supposed to be a celebration of digital health's banner year. It's instead shaping up to be a microcosm of another distressing moment in the pandemic. → https://is.gd/lExrHY | 17:05 |
Brainstorm | Updates for Germany: +2917 cases (now 3.8 million), +12 deaths (now 92257) since 23 hours ago | 17:06 |
Brainstorm | New from Reddit (test): Friday 06 August 2021 Update: submitted by /u/HippolasCage to r/CoronavirusUK → https://is.gd/gB01rX | 17:16 |
Brainstorm | New from Contagion Live: us: Double Vaccinated Three Times Less Likely to Test Positive for COVID-19 → https://is.gd/j8AxGG | 17:26 |
Brainstorm | Updates for Kosovo: +271 cases (now 109310) since 23 hours ago | 17:31 |
Brainstorm | New from NPR: United Becomes First Major U.S. Airline To Require Employees Be Vaccinated: Citing "incredibly compelling" evidence that COVID-19 vaccines are safe and effective, United CEO Scott Kirby announced the policy change on Friday. It will affect the carrier's 67,000 U.S. employees. → https://is.gd/cyi80M | 17:48 |
Brainstorm | Updates for United Kingdom: +31442 cases (now 6.0 million) since 15 hours ago — Italy: +6599 cases (now 4.4 million), +24 deaths (now 128187) since 23 hours ago | 18:08 |
Brainstorm | New from Ars Technica: Science: GOP congressman gets COVID-19 after suing Pelosi over mask rule → https://is.gd/MFzpmm | 18:09 |
LjL | looks like the UK and Italy have both stopped... stopping growing | 18:10 |
de-facto | so we have R-value plots? | 18:17 |
de-facto | hmm whats with UK? does it go up again? | 18:18 |
de-facto | http://offloop.net/covid19/?default=United%20Kingdom;Italy&byPopulation=yes&cumulative=no&miscType=Reff&leftTrim=400 | 18:20 |
de-facto | looks like in UK reproduction raised again since 2021-07-28 R ~ 0.73 and 2021-08-05 R ~ 1.0 hence dR/dt ~ (1.0 - 0.73)/8d ~ 0.03375/d ~ 1/30d | 18:22 |
Brainstorm | New from Reddit (test): CoronaVirus_2019_nCoV: Lambda COVID variant "a potential threat to human society," researchers say → https://is.gd/Zqkb6m | 18:41 |
Brainstorm | New from In The Pipeline: Viral Knots: The current pandemic has made everyone think a lot more about viruses than they ever had any desire to, but they’re a constant background to our lives – and to the lives of pretty much every living creature. Humans have their viruses, other mammals have theirs (with occasional catastrophic overlaps), and [... want %more?] → https://is.gd/Fih5b8 | 19:02 |
Brainstorm | Updates for Sri Lanka: +2794 cases (now 324223) since 22 hours ago — North Macedonia: +325 cases (now 157251), +1 deaths (now 5502) since a day ago — Yemen: +27 cases (now 7131), +1 deaths (now 1384) since a day ago — Mali: +18 cases (now 14633) since 21 hours ago | 19:11 |
Brainstorm | New from Contagion Live: The Delta Variant: What it Means for the Vaccinated and Unvaccinated: Recent breakthrough infections have experts looking closely at the true risks of the COVID-19 delta variant and how we can protect ourselves. → https://is.gd/WkyoJI | 19:13 |
Brainstorm | Updates for Spain: +21561 cases (now 4.6 million), +75 deaths (now 82006) since a day ago — Canada: +24 deaths (now 26656) since 17 hours ago | 19:36 |
Brainstorm | New from r/WorldNews: worldnews: Russia records about 463,000 excess deaths in pandemic -Reuters calculations → https://is.gd/h47oxf | 19:55 |
Brainstorm | New from COVID19 Vaccine Tracker: Andy Becker: Bagheiat-allah University of Medical Sciences: COVID-19 Recombinant RBD Protein Vaccine → https://is.gd/7u1GtD | 20:06 |
rpifan | i dont see novavax | 20:07 |
nixonix | old but big (feb): placebo group for Novavax’s vaccine in South Africa🇿🇦: people with prior #COVID19 infections appeared just as likely to get sick as people without prior infections | 20:19 |
nixonix | https://twitter.com/drericding/status/1358065355785134083 | 20:19 |
nixonix | The good thing is that the Novavax vaccine was roughly equally ~50% effective (in South Africa 🇿🇦, higher elsewhere) against the virus regardless of past infection (denoted as serostatus positive or negative in the figure) | 20:20 |
nixonix | .title https://www.theatlantic.com/science/archive/2020/10/single-tree-species-may-hold-key-coronavirus-vaccine/616792/ | 20:22 |
Brainstorm | nixonix: From www.theatlantic.com: A COVID-19 Vaccine Could Rely on Rare Trees in Chile - The Atlantic | 20:22 |
rpifan | not a good thing | 20:24 |
rpifan | to destroy rare trees | 20:25 |
nixonix | they are growing those, if i recall. it was a while back i read the article, i thought you guys might be interested | 20:25 |
nixonix | cultivating | 20:26 |
rpifan | hm | 20:27 |
nixonix | there are some interesting trees, pacific yew for chemotherapeutic drugs, arrow poison in that tree in asia, then those in americas to stun fish. and sassafras for root beer (banned in usa nowdays i think, use of sassafras in it) | 20:32 |
nixonix | and that tree they use for mdma, what was it again | 20:32 |
Brainstorm | Updates for Albania: +149 cases (now 133591), +1 deaths (now 2458) since a day ago | 20:38 |
Brainstorm | New from CIDRAP: COVID-19 Scan for Aug 06, 2021: COVID-19 antibodies after 7 months Long COVID in hospitalized patients → https://is.gd/S2FLoZ | 20:48 |
nixonix | https://twitter.com/DrEricDing/status/1423483720665747460 | 20:50 |
nixonix | https://twitter.com/DrEricDing/status/1423484326751084548 | 20:51 |
nixonix | .title https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7716952/ | 20:52 |
Brainstorm | nixonix: From www.ncbi.nlm.nih.gov: Possible modes of transmission of Novel Coronavirus SARS-CoV-2: a review | 20:52 |
nixonix | "some of the other possible modes of transmission are being explored by the researchers, with some studies suggesting the viral spread through fecal-oral, conjunctival secretions, flatulence (farts)" | 20:53 |
OrTh0DoX | Are there any studies being done on why a person still can get serious illness from COVID-19 even after 2 doeses of vaccine? 2nd dose was administered 5 months ago. | 20:54 |
LjL | why? mainly because the new variants aren't really covered by the original vaccines | 20:54 |
OrTh0DoX | No. From what I know the person contracted is the Delta variant | 20:55 |
LjL | what's "no" about that? | 20:55 |
LjL | Delta is not covered by the current vaccines | 20:55 |
LjL | the antibodies elicited are much less effective than against the original variants | 20:55 |
LjL | there are certainly studies on *that* | 20:55 |
OrTh0DoX | I see. even with 3rd booster shot is still futile? | 20:56 |
LjL | not necessarily, since the antibodies appear to skyrocket after a 3rd shot according to Pfizer. but the ideal thing would be a vaccine made specifically for Delta, which Pfizer is worked on | 20:56 |
LjL | working on* | 20:56 |
LjL | Moderna is working on a Beta vaccine, at least they have it on trial already, they're probably working on more too | 20:57 |
nixonix | waning antibodies and b-cell maturating stopping after the 2nd dose. for indian variant its evasiveness isnt close to SA variant, the efficacy drops only to around half if its recent vaccination (i use inverse ratio, the share that gets infection) | 20:57 |
LjL | but since the bad variants have similar mutations, it's possible the Beta vaccine will be effective against Delta too | 20:57 |
OrTh0DoX | great to know! And I hope these studies will include the Delta+ variant | 20:59 |
Brainstorm | Updates for Aruba: +262 cases (now 12262) since a day ago | 21:03 |
LjL | de-facto, hmm does https://cov2tree.org/ offer anything that the other friendly sites of ours don't? because then i'll add it, but otherwise its interface seems slow and clunky in comparison to the others | 21:04 |
Arsanerit | I read something about nasal vaccines, are those somehow special? | 21:04 |
LjL | Arsanerit, current vaccines probably don't protect the upper airways, which may drive continued transmission | 21:05 |
LjL | there is some sort of... not quite an immune barrier, but something like that between the main immune system and the mucosal system | 21:05 |
Arsanerit | That's why there's still asymptomatic infections with the current vaccines, in particular with delta? | 21:06 |
nixonix | what was known about pfizers and modernas vacc afficacy vs SA variant? | 21:06 |
Arsanerit | Can we expect those better (?) nasal vaccines any time soon? | 21:06 |
LjL | Arsanerit, i think it's a combination of that, and Delta simply evading the vaccines | 21:07 |
Arsanerit | apparently the Moderna vaccine is called Spikevax®. | 21:07 |
Arsanerit | enwiki says Comirnaty® is 79% effective against asymptomatic infection for Delta and 75% for Beta. | 21:09 |
LjL | nixonix, https://investors.modernatx.com/news-releases/news-release-details/moderna-covid-19-vaccine-retains-neutralizing-activity-against https://investors.modernatx.com/news-releases/news-release-details/moderna-covid-19-vaccine-retains-neutralizing-activity-against https://www.pfizer.com/news/press-release/press-release-detail/pfizer-and-biontech-confirm-high-efficacy-and-no-serious (CI 53% to 100%) https://www.medrxiv.org/content/10.1101/2021.04.06.21254882v | 21:09 |
LjL | 2 (odds ratio 8:1) https://www.nejm.org/doi/full/10.1056/NEJMc2104974 (75% efficacy) | 21:09 |
LjL | Arsanerit, they are not better, they are complementary | 21:09 |
Brainstorm | New from WebMD: Dangerous Price of COVID Rules for Women, Children in Africa: COVID-19 safety responses have had harmful, and life-threating, effects for women and children across the continent. → https://is.gd/ahYM7E | 21:09 |
Arsanerit | LjL: ah, ok. When can we expect those? | 21:10 |
LjL | Arsanerit, i don't know. India is already using one | 21:10 |
Arsanerit | Is it helping (in India)? | 21:13 |
LjL | i don't know | 21:13 |
de-facto | LjL, its pretty neat because of the zooming feature, otherwise it would be difficult to browse 1M+ sequences | 21:22 |
de-facto | https://twitter.com/firefoxx66/status/1416060059902255104 | 21:22 |
de-facto | https://twitter.com/theosanderson/status/1412078714557435904 | 21:22 |
de-facto | https://github.com/theosanderson/taxodium | 21:22 |
nixonix | if we knew with high confidence efficacy for symptomatic infection and for pcr positive, the difference would be asymptomatic infections (considering differencies in age groups, waning etc) | 21:23 |
de-facto | http://hgdownload.soe.ucsc.edu/goldenPath/wuhCor1/UShER_SARS-CoV-2/ | 21:23 |
nixonix | but theres also that presymptomatic shedding period, and with indian variant it's share seems to be bigger | 21:23 |
nixonix | https://twitter.com/jburnmurdoch/status/1413423095881347077 | 21:24 |
de-facto | LjL, also it got very powerful search functions, i kinda like https://cov2tree.org/ | 21:25 |
LjL | de-facto, ah it's specifically about public sequences | 21:25 |
nixonix | over 200M identified cases, so it has 0.5% of them | 21:26 |
LjL | it takes a *long* time to load | 21:27 |
nixonix | half british and 5% danish? | 21:27 |
nixonix | https://twitter.com/imgrund/status/1419080609226428417 | 21:29 |
Brainstorm | New from StatNews: Biotech: STAT+: Adagio raises $300 million in IPO, looks to advance Covid-19 antibody therapy → https://is.gd/ofBmoQ | 21:30 |
de-facto | for me it loads in 8s | 21:31 |
de-facto | imho quite impressive for displaying 1,254,751 sequences from INSDC, COG-UK and CNCB | 21:31 |
-RSSBot[LjLmatrix- Recent Commits to links:master: Add Cov2Tree ( https://github.com/ljl-covid/links/commit/78b2ced6ac6eacb85887b5e072846b0dee2abc78 ) | 21:33 | |
de-facto | also note the Genbank links, easy to get the full sequence that way | 21:33 |
de-facto | i guess you noticed mousewheelzoom etc | 21:34 |
nixonix | doesnt show anything, possibly because disabled webgl - but i checked that around half are british indeed. only a few from denmark though (and finland or sweden) | 21:36 |
-RSSBot[LjLmatrix- Recent Commits to links:master: Add source of Cov2Tree data ( https://github.com/ljl-covid/links/commit/934a9f6f49736e8ef195167c426a85e9972a1b79 ) | 21:38 | |
Brainstorm | Updates for Burundi: +369 cases (now 8088) since 16 hours ago — France: +44 deaths (now 112214) since 23 hours ago | 21:40 |
Brainstorm | New from https://covid19.specops.network : ljl-covid: Add source of Cov2Tree data → https://is.gd/q546HE | 21:41 |
nixonix | that mAb above, targets conserved epitope of RBD which is good. this is sub-q so they can be used that way too (but these are affected by mutations of indian variant): | 21:45 |
nixonix | .title https://www.nejm.org/doi/full/10.1056/NEJMoa2109682?query=featured_home | 21:45 |
Brainstorm | nixonix: From www.nejm.org: Subcutaneous REGEN-COV Antibody Combination to Prevent Covid-19 | NEJM | 21:45 |
nixonix | around 3% of population apparently immunosuppressed in usa. those new variants seem to be emerging often from high HIV prevalence areas (not sure how it is in uk though), maybe from in-host evolution in immunocompromised | 21:51 |
nixonix | "The recent demonstration of the use of combination monoclonal antibodies for preventing SARS-CoV-2 acquisition in nursing homes and home settings suggests that passive antibody prophylaxis may be another approach for immunosuppressed patients who do not have an adequate immune response to vaccination or for patients and their family members with | 21:51 |
nixonix | high-risk exposure | 21:51 |
nixonix | although its like 500-2k per pop. third dose of vacc should help (if its allowed) | 21:52 |
nixonix | well according to wiki, india and brazil arent that high hiv prevalence countries. or even brazil | 21:54 |
-RSSBot[LjLmatrix- Recent Commits to links:master: Removing Google's tracker, which doesn't appear to exist as such anymore ( https://github.com/ljl-covid/links/commit/8e3e96e6028f93cd67a33e6d5052fc6c22188177 ) | 21:58 | |
de-facto | hmm would monoclonal antibodies not produce an absolutely static selection, e.g. unable to follow antigenic due to lack of any feedback, thereby possibly give rise to new variants if the pathogen can escape the host treated before its neutralized? | 21:58 |
de-facto | LjL, this https://news.google.com/covid19/map ? | 22:00 |
LjL | de-facto, no it was a different address, i'll add that one | 22:01 |
de-facto | i mean was it that functionality? i dont remember the previous one | 22:02 |
LjL | i guess | 22:02 |
Brainstorm | New from WebMD: New Biomaterial Vaccines Aim to Ward Off Future Pandemic Threats: Scientists are banking on the idea the structure of a future pathogen to threaten human health will be like the ones they already know about as they design next-generation vaccines. → https://is.gd/JzNqrF | 22:02 |
-RSSBot[LjLmatrix- Recent Commits to links:master: Removing CovidStat, as it redirects to an empty website ( https://github.com/ljl-covid/links/commit/8e6c8ad23cfddac03b8608d14a84db3b6d40517f ) | 22:03 | |
nixonix | moderna: Variant-specific booster candidates: mRNA-1273.351 & mRNA-1273.617 (new) III. Multi-valent platform: mRNA-1273.211 & mRNA-1273.213 (new) | 22:03 |
nixonix | We believe that increased force of infection resulting from Delta, non-pharmaceutical intervention (NPI) fatigue, and seasonal effects (moving indoors) will lead to an increase of breakthrough infections in vaccinated individuals | 22:03 |
nixonix | While we see durable Phase 3 efficacy through 6 months, we expect neutralizing titers will continue to wane and eventually impact vaccine efficacy Given this intersection, we believe dose 3 booster will likely be necessary prior to the winter season | 22:03 |
LjL | de-facto, this is also sourced mainly from Wikipedia, the old was too | 22:04 |
nixonix | .title https://investors.modernatx.com/static-files/c43de312-8273-4394-9a58-a7fc7d5ed098 | 22:04 |
Brainstorm | nixonix: From investors.modernatx.com: Moderna 2Q21 Earnings Call (Chasen Richter) | 22:04 |
de-facto | LjL, hmm weird their github still exists but seems somewhat abandoned, so maybe their domain expired? https://github.com/COVID19-SARS-CoV-2/web-covid-api | 22:07 |
LjL | updated very long ago | 22:07 |
de-facto | oh wow nixonix nice find | 22:07 |
-RSSBot[LjLmatrix- Recent Commits to links:master: Add new address for Google tracker ( https://github.com/ljl-covid/links/commit/0b851607e71d3f4407d3f0cd3c48ea8447a04f17 ) | 22:08 | |
nixonix | .title https://investors.modernatx.com/news-releases/news-release-details/moderna-reports-second-quarter-fiscal-year-2021-financial/ | 22:11 |
Brainstorm | nixonix: From investors.modernatx.com: Moderna Reports Second Quarter Fiscal Year 2021 Financial Results and Provides Business Updates | Moderna, Inc. | 22:11 |
nixonix | We are also in the process of developing a booster tailored to the Delta variant (mRNA-1273.617), and anticipate developing a multivalent booster—referred to as mRNA-1273.213—that combines mRNA-1273.617 with another COVID-19 candidate. | 22:11 |
nixonix | CMV vaccine (mRNA-1647): Our vaccine against cytomegalovirus, or CMV (mRNA-1647) is a vaccine combining six mRNAs in a single vial, which encode for two antigens located on the surface of CMV: five mRNAs encoding the subunits that form the membrane-bound pentamer complex and one mRNA encoding the full-length membrane-bound glycoprotein B (gB) | 22:11 |
nixonix | they have other vaccines coming too https://www.marketwatch.com/investing/stock/mrna/SecArticle?guid=15139868 | 22:12 |
-RSSBot[LjLmatrix- Recent Commits to links:master: Remove duplicate Bing tracker entry ( https://github.com/ljl-covid/links/commit/a7e483512469bb5e5001bf4a7120acaa9ae0ead9 ) | 22:13 | |
-RSSBot[LjLmatrix- Recent Commits to links:master: Remove Plague.com, which doesn't respond anymore ( https://github.com/ljl-covid/links/commit/c19f144e6d06edf03c296abf662f6258e5221081 ) | 22:18 | |
nixonix | theres a vaccine candidate called ufovax. i considered using it as a nick, but youdve thought its just silly idea | 22:24 |
nixonix | .title https://emedicine.medscape.com/article/2500139-overview | 22:24 |
Brainstorm | nixonix: From emedicine.medscape.com: COVID-19 Vaccines: Overview, mRNA Vaccines, Viral Vector Vaccines | 22:24 |
Brainstorm | New from CIDRAP: US reaches 50% fully vaccinated against COVID: Lisa Schnirring | News Editor | CIDRAP News Aug 06, 2021 In other developments, one new study found vaccination provides better protection than previous COVID-19 infection and another high protection against hospitalization in older age groups. → https://is.gd/oufMYo | 22:44 |
nixonix | moderna: ≥4 months after dose 2** 92.4% (84.3, 96.8) - ** To earliest of study discontinuation, PDV/unblinding, or data cutoff date of 3/26/2021, longest follow up to 241 days | 22:47 |
de-facto | i like their approach to put multiple s-protein signatures in one update shot | 22:53 |
LjL | Moderna? | 22:59 |
nixonix | i like their CMV vaccine | 23:03 |
nixonix | anyways, while those 4+ month results look strong, it was pre 617.2, and the problem with pfizer is especially over 60 yo, which are probably small share of modernas trial. hopefully uk releases more data on both soon | 23:05 |
Arsanerit | Spikevax® | 23:12 |
LjL | you know you don't really have to include the ® | 23:13 |
nixonix | have they compared ab titers between pfizer and moderna? when they are very similar but moderna has 100 Mcg and pfizer 30, does moderna produce higher titers on average? | 23:17 |
LjL | have you seen in their financial report that they kind of assume they can use 50 Mcg in the future? | 23:19 |
nixonix | moderna has tested half doses for 3rd dose - and if i recall also for 2nd or even 1st in the past. pfizer induced less myo/pericarditis than moderna, so it would be better for 11-15 yo | 23:19 |
nixonix | and younger kids have smaller doses anyway | 23:19 |
nixonix | yeah, its prob way to go, and enough | 23:19 |
LjL | interesting, the spotlight on myocarditis was basically just on Pfizer | 23:20 |
nixonix | https://twitter.com/itosettiMD_MBA/status/1423600429569564672 | 23:20 |
nixonix | i dont remember what they had in those tables, but i saw that tweet, i guess its true | 23:21 |
Brainstorm | New from COVID Zotero group: Excess Deaths Associated with COVID-19: Type Web Page URL https://www.cdc.gov/nchs/nvss/vsrr/covid19/excess_deaths.htm Date 2021-08-05T01:32:14Z Accessed 2021-08-06 21:21:17 Language en-us Abstract Figures present excess deaths associated with COVID-19 at the national and state levels. → https://is.gd/h8vtzP | 23:23 |
Arsanerit | I know I don't have to | 23:27 |
Brainstorm | New from COVID Zotero group: Modelling the COVID-19 epidemic and implementation of population-wide interventions in Italy: Type Journal Article Author Giulia Giordano Author Franco Blanchini Author Raffaele Bruno Author Patrizio Colaneri Author Alessandro Di Filippo Author Angela Di Matteo Author Marta Colaneri URL [... want %more?] → https://is.gd/i3mwhY | 23:34 |
LjL | Zotero has an issue when adding "things that aren't papers" that in theory it supports "web pages", but in practice 1) if those pages *link to* studies, apparently, you must select one of the linked study and you can't just add the page itself 2) sometimes it just doesn't like a given webpage, maybe it can't parse it, i dunno, and then you can't add it | 23:36 |
LjL | i think it can't replace the github page, although it may be better for a larger number of papers | 23:36 |
nixonix | according to ons survey, not all regions of uk or even england turned down at the same time (as was pretty much the case on daily cases). 6/9 regions of england | 23:47 |
nixonix | .title https://www.ons.gov.uk/peoplepopulationandcommunity/healthandsocialcare/conditionsanddiseases/bulletins/coronaviruscovid19infectionsurveypilot/6august2021 | 23:47 |
Brainstorm | nixonix: From www.ons.gov.uk: Coronavirus (COVID-19) Infection Survey, UK - Office for National Statistics | 23:47 |
nixonix | uk been on kinda plateau for awhile now, going up and down a bit | 23:48 |
nixonix | ah and there was age group graphs too, the peak was on 17 yo on most regions. northern ireland was 13-14 yo i think. ideas whys that? here the top spreaders have been 18-24 lately, in bar age | 23:51 |
nixonix | is it 18 in uk or 16 something, pub age? | 23:51 |
nixonix | .title https://www.medscape.com/viewarticle/954481 | 23:55 |
Brainstorm | nixonix: From www.medscape.com: Adjunctive Thiamine in Critically Ill COVID-19 Patients | 23:55 |
nixonix | There was significant association between thiamine use with in-hospital mortality (OR = 0.39; 95% CI 0.19–0.78; P value = 0.008) as well as the 30-day mortality (OR = 0.37; 95% CI 0.18–0.78; P value = 0.009). Moreover, patients who received thiamine as an adjunctive therapy were less likely to have thrombosis during ICU stay [OR (95% CI) 0.19 | 23:56 |
nixonix | (0.04–0.88), P value = 0.03] | 23:56 |
nixonix | maybe ill start typing with bold from now on... | 23:57 |
TurboTech | Afternoon | 23:58 |
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