| nixonix | now in situation like this, its possible that delta or something similar variant (very high transmission, but medium evasion) will take over again from that SA-type variant. depending how fast 3rd doses are administered | 00:00 |
|---|---|---|
| dTal | /join #nixonix | 00:01 |
| nixonix | with one #? | 00:01 |
| dTal | good point, is your source code free? :p | 00:01 |
| nixonix | im afraid not | 00:02 |
| nixonix | lets see if im right. should start to show in countries with slow 3rd dose rate maybe 6-7 months after theyve got some level of herd immunity without much restrictions (depending how much and fast they will get SA variant in the country) | 00:05 |
| lastshell | how is the end of the world going ? | 00:28 |
| dTal | everything is proceeding as I have forseen it | 00:31 |
| lastshell | dTal care to expand a little bit I lose track this last days I know that we have now a "mu" variant | 00:32 |
| de-facto | greek letters are a finite set... WHO would have thought THAT :D | 00:32 |
| lastshell | is been bck and fwd the 3rd booster approval here in usa | 00:32 |
| nixonix | .title https://scitechdaily.com/ultra-low-doses-of-inhaled-nanobodies-prevents-and-treats-severe-covid-19-in-hamsters/ this idea seems to be still alive, somewhat | 00:33 |
| Brainstorm | nixonix: From scitechdaily.com: Ultra-Low Doses of Inhaled Nanobodies Prevents and Treats Severe COVID-19 in Hamsters | 00:33 |
| lastshell | they should use semver.org | 00:33 |
| nixonix | they already chose to use constellation names | 00:33 |
| specing | inhaled nanobodies? oh my, antivaxxers will have a field day with that one | 00:33 |
| de-facto | nixonix, i never understoof why it did not progress faster, what is the problem with those? | 00:34 |
| de-facto | *understood | 00:34 |
| lastshell | why use something that has also finite options ? | 00:34 |
| Brainstorm | New from The Lancet (Online): [Comment] The Lancet Commission on water, sanitation and hygiene, and health: In 2010, access to water and sanitation was recognised as a human right and, in 2015, an ambitious Sustainable Development Goal (SDG) of achieving universal access to safely managed water, sanitation, and hygiene (WASH) services by 2030 was [... want %more?] → https://is.gd/K88Mfa | 00:36 |
| nixonix | something easi to remember, but almost unlimited combinations... like passwords! combinations of random words. or hexadecimals | 00:36 |
| specing | the horse battery staple variant | 00:37 |
| nixonix | rea!s3cretVar1ant | 00:38 |
| lastshell | I wish there was a test to see how good or bad you can resist covid | 00:40 |
| de-facto | the PANGO Lineage allows to include ancestors, imho a valuable feature | 00:41 |
| de-facto | there is lastshell :D | 00:41 |
| nixonix | not approved by CDC | 00:41 |
| de-facto | it just, well it can go wrong, its called challenge with the real pathogen | 00:41 |
| lastshell | lmao | 00:41 |
| lastshell | yeah I'm not joe rogan to get quick treatmeants | 00:42 |
| nixonix | fauci said a few months ago, that there are not commercially available way to find out if the protection is still good or not, so he are just waiting for news if breakthroughs start to get common | 00:42 |
| nixonix | he is | 00:43 |
| de-facto | but yeah it would be neat if we had a harmless test, such as a prick-test etc that could test for risk from COVID without posing a real problem to the individual | 00:43 |
| nixonix | el cheapo surrogate neutralization test from ali express | 00:44 |
| lastshell | sounds like el chapo not sure if the brand name give me confidence :P | 00:45 |
| lastshell | the news fear mongering or is true young and healthy indivuals also die ? | 00:47 |
| Brainstorm | New from Eric Topol: @EricTopol: Delta in Denmark, new @TheLancetInfDis https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(21)00580-6/fulltext2.8 X fold risk of hospitalization compared with Alpha, replicating a recent report from England (2.3 X)That heightened risk was not significant with vaccination (1.25 X, [95% CI 0.34,4.6]) → https://is.gd/8B6prZ | 00:47 |
| de-facto | but seriously cant we provoke the immune system with some antigen test and observe a spectrum of markers to try to correlate its reaction somehow with later severity in case that individual is unlucky enough to catch it in real life? | 00:47 |
| lastshell | I guess so | 00:48 |
| de-facto | its much more complex than allergies or such, but still, can we exclude that something like that could possibly work? | 00:48 |
| lastshell | I'm still microdosing (using kn95 masks in the stores) but not staying long just for the stuff I need and go | 00:50 |
| lastshell | and continue to do exercise this last 2 weeks more than 250 minutes | 00:51 |
| lastshell | the recommended is 150 minutes | 00:51 |
| lastshell | https://www.mayoclinic.org/healthy-lifestyle/fitness/expert-answers/exercise/faq-20057916 | 00:52 |
| nixonix | " Expect brittle immune systems in those without thymus function to replenish aged t cells" i wonder how likely are those damaged t-cell repair functions, or if there is some information nowdays | 00:52 |
| Brainstorm | New from COVID19 Vaccine Tracker: Andy Becker: Bagheiat-allah University of Medical Sciences: COVID-19 Recombinant RBD Protein Vaccine → https://is.gd/7u1GtD | 00:57 |
| nixonix | "We found a similarly increased risk of hospitalisation associated with the delta variant (risk ratio 2·83 [95% CI 2·02–3·98] | 00:59 |
| nixonix | compared to alpha. aka kent | 00:59 |
| nixonix | innit | 00:59 |
| nixonix | ratios are higher for young, and a bit lower for over 60 yo | 01:01 |
| lastshell | well that is kind of good and bad for me | 01:01 |
| nixonix | shows in supplementary material. wide CIs in age groups, but looks like it | 01:02 |
| oft_gegong | testing | 01:06 |
| LjL | success | 01:07 |
| LjL | i think | 01:07 |
| oft_gegong | so I have two issues with covid vaccines: (1) why are the vaccine containers labelled "COVID vaccine" versus its real ingredients? (2) why are there two shots for one vaccine? sounds 900%unnatural. | 01:08 |
| dTal | does "testing" mean "testing people | 01:09 |
| dTal | 's patience" | 01:09 |
| Cashlin | among other things im sure | 01:09 |
| LjL | i take it back, the testing was unsuccessful | 01:10 |
| oft_gegong | I'm for real. I'm for real. | 01:10 |
| dTal | basically, they're trying to hide the real ingredients from you so you won't realize the terrible, harmful things in it. Fortunately there's Google | 01:10 |
| Cashlin | thanks LjL | 01:10 |
| Cashlin | when I took mine it listed them all on a paper they gave me | 01:10 |
| dTal | and the second shot is to top up the batteries of all the microchips from the first shot | 01:11 |
| nixonix | 39% of nonhospitalized patients exhibited no detectable neutralization against B.1.351. Moreover, monoclonal neutralizing antibodies show sharp reductions in their binding kinetics and neutralizing potential to B.1.351 and P.1 but not to B.1.1.7 | 01:11 |
| Cashlin | the human body contains formeldahyde even in small doses, holy shit everyone stop eating apples, the seeds have CYANIDE!! | 01:11 |
| Cashlin | hahahahaha dTal you had me going in the first half | 01:11 |
| nixonix | .title https://www.science.org/doi/10.1126/sciadv.abj5365 | 01:12 |
| Brainstorm | nixonix: From www.science.org: Emerging SARS-CoV-2 variants of concern evade humoral immune responses from infection and vaccination | 01:12 |
| dTal | no it's true, whoever heard of a "booster shot"?? it's sketchy as shit is what it is | 01:12 |
| LjL | nixonix, i think that kinda shows how inefficient peer review is in the COVID era... a paper on variants published *now*, NOT assessing Delta ;( | 01:13 |
| dTal | literally no vaccine ever has had booster shots | 01:13 |
| LjL | someone on Twitter just DM'd me "Boo!" | 01:13 |
| LjL | now i want to complete with "...stershot" | 01:13 |
| Cashlin | hahaha | 01:14 |
| Cashlin | yeah why would i need to sit in a higher chair for another shot? smh | 01:14 |
| dTal | Twitter is an ambitious medium in which to attempt a jump scare | 01:14 |
| Cashlin | just add ":P" | 01:15 |
| LjL | dTal, if you knew the person, you'd have long accepted the lack of sensicalness | 01:15 |
| specing | dTal: tetanus? | 01:15 |
| nixonix | its time to look at another variants now, when the share of immunized has increased, and the protection is waning fast. SA or similar | 01:15 |
| LjL | dTal, i think you forgot the /s emoji for specing | 01:16 |
| specing | dTal: tick-borne meningoencephalitis vaccine has boosters every 5 years | 01:16 |
| specing | lol | 01:16 |
| LjL | what do you mean Unicode has issued no /s emoji yet?! | 01:16 |
| dTal | specing: I think that was for the 4g microchips | 01:16 |
| LjL | yeah but 4G is still current, they're only decommissioning 3G | 01:16 |
| LjL | which was the smallpox vaccine i think? | 01:16 |
| LjL | so smallpox is coming back now | 01:16 |
| nixonix | but sure, delta should have been included. maybe next version | 01:16 |
| Cashlin | we should have more tick borne pathogen vaccines | 01:17 |
| specing | oft_gegong: (2) because it boosts efficacy .There's even a 3-shot one that recently got approved in India or something | 01:18 |
| oft_gegong | specing, sounds like BS (not BE) to me | 01:18 |
| dTal | can't we just engineer a bunch of mosquitos where getting bitten vaccinates you against covid | 01:18 |
| -RSSBot[LjLmatrix- Zotero / COVID links Group / Top-Level Items: Emerging SARS-CoV-2 variants of concern evade humoral immune responses from infection and vaccination ( https://www.zotero.org/groups/covid_links/items/44JBHMTU ) | 01:18 | |
| specing | and there's multiple 1-shot ones, like janssen and sputnik-lite | 01:18 |
| specing | oft_gegong: BS? | 01:19 |
| oft_gegong | specing, listen. Okay. There's no vaccine out there for anything else that has two vaccines for. | 01:19 |
| dTal | specing, feed not the troll | 01:19 |
| oft_gegong | dTal, I'm being a 17%troll. | 01:19 |
| oft_gegong | 83%non-troll | 01:20 |
| LjL | dTal, we've kinda been feeding it all long though, except specing is doing it for serious ;( | 01:20 |
| LjL | along | 01:20 |
| specing | I'ts all right, I'm falling asleep and can't do anything serious anyway | 01:20 |
| specing | oft_gegong: sorry, but I'm too tired to parse that sentence | 01:21 |
| LjL | oft_gegong, you're right in that i don't believe there is any vaccine for a vaccine | 01:21 |
| oft_gegong | specing, vaccines don't have a booster shot. Something is wrong withe the vaccine. | 01:21 |
| dTal | it's true. You caught them. well done | 01:22 |
| LjL | okay let's move on from the obvious untruth, it was like fun for a while but it's not now | 01:22 |
| oft_gegong | I've figured it out! I found the truth. *unleashing 100 balloons* | 01:23 |
| specing | oft_gegong: I just told you, tick-borne meningoencephalitis and tetanus have booster shots | 01:24 |
| specing | oft_gegong: *vaccines. The latter is even mandatory in my county | 01:24 |
| oft_gegong | specing, oh I missed that. sorry. Okay I get it now. | 01:25 |
| dTal | sounds suspicious to me | 01:25 |
| dTal | how can we even trust this "specing" | 01:25 |
| nixonix | there are lots of vaccines needing 3 doses. hpv, hepatitis, childrens 6-in-1, ... i saw longer list in some tweet i cant find rn | 01:25 |
| dTal | could be feeding us all kinds of misinfo | 01:26 |
| specing | ah yeah, HPV is 3 doses for >15 years old. But it's part of initial vaccination and thus not really a booster? | 01:26 |
| dTal | oh sure nixonix I bet you can't find that tweet, because it DOESNT EXIST right?? | 01:26 |
| specing | Or maybe we could call it a booster, since older people's immune systems need an additional boost, hehe | 01:27 |
| nixonix | you got me. all the other stuff ive said here, is not just made up | 01:27 |
| dTal | that's just what you'd like us to think huh | 01:27 |
| dTal | alright alright, I'm done :p | 01:28 |
| specing | Today I read that nearly all sexually active people catch HPV in the course of their lives | 01:28 |
| nixonix | no more beer for you today | 01:28 |
| specing | like wtf, why aren't vaccinations for HPV mandatory | 01:28 |
| dTal | guess we don't have to worry then eh specing ho ho ho | 01:28 |
| LjL | specing, we only semi-recently started figuring out that HPV causes nasty things | 01:28 |
| specing | I looked at a price list of a vaccination office and it's 200 eur to get vaccinated against HPV D: | 01:29 |
| LjL | HPV vaccination is now strongly recommended here for prepubescent children | 01:29 |
| specing | LjL: yeah, a whole bunch of cancers | 01:29 |
| dTal | wait what, you can get vaccinated for that? | 01:29 |
| LjL | yes | 01:29 |
| dTal | yeah that's a wtf | 01:29 |
| LjL | i mean, *you* probably can't, usefully | 01:29 |
| dTal | why is every single person not vaccinated | 01:29 |
| LjL | that's because you've been naughty | 01:29 |
| dTal | why is it still a thing | 01:30 |
| nixonix | and varicella stays in brain, was it. all or just for some? | 01:30 |
| dTal | ...are you saying I probably have HPV already LjL? | 01:30 |
| LjL | dTal, i would imagine so | 01:30 |
| LjL | dTal, also https://en.wikipedia.org/wiki/HPV_vaccine#History may have some of the answers to your startled questions | 01:30 |
| dTal | I would imagine it does but it's more fun to be startled in here | 01:31 |
| oft_gegong | I have the disease you guys..I'm gonna die..I'm gonna DIE. YOU HEAR ME. I'M DEAD. *fake dies* | 01:31 |
| nixonix | whose buddy is this | 01:32 |
| LjL | you're doubtlessly gonna die | 01:32 |
| dTal | oft_gegong there isn't room for two loopy people in the channel at once, and I've got the conch right now | 01:32 |
| * oft_gegong resigns | 01:32 | |
| LjL | i want a retroactive tinnitus vaccine | 01:33 |
| specing | lol >retroactive | 01:33 |
| dTal | I think the word you're searching for is "cure" | 01:33 |
| oft_gegong | Or Heal 3 in RPG terms | 01:33 |
| nixonix | .title https://twitter.com/EricTopol/status/1433907516245569542 whats the newest plan in usa? | 01:35 |
| Brainstorm | nixonix: From twitter.com: Eric Topol (@EricTopol): "How to lose public confidence? 1. Announce a booster program on Sept 20 for all at 8 months post-vaccine 2. Change it to 6 months, then 5 months, then back to 8 3. Lack of [...] | 01:35 |
| LjL | dTal, no 'cause it has to be a cure that ensures it never comes back | 01:36 |
| nixonix | it could be psychosomatic. NLP... | 01:36 |
| LjL | nixonix, varicella is a herpesvirus, i think they stay in nerves, but not specifically in the brain (if HSV gets into the brain it's *trouble*) | 01:36 |
| LjL | nixonix, psychosomatic in only the left ear for 4 years, sure | 01:36 |
| nixonix | cns i think i read some day | 01:37 |
| LjL | maybe, hope not, that'd be scary | 01:37 |
| LjL | anyway it does stay around (somewhere) for everyone afaik but for most people the immune system keeps it at bay throughout adulthood | 01:37 |
| LjL | at some point it may resurface as shingles | 01:37 |
| LjL | which is not fun, but you can get vaccinated against *that*, which doesn't get rid of the virus, but gives your immune system a gentle reminder | 01:38 |
| nixonix | The primary infection causes chickenpox or varicella after which it becomes latent in the brain, dorsal nerve roots, and autonomic ganglia and may reactivate to cause herpes zoster | 01:39 |
| nixonix | but i really dont know much about non-rona viruses. educate me | 01:39 |
| specing | > In early 2013 the two companies who sell the most common vaccines announced a price cut to less than US$5 per dose to poor countries, as opposed to US$130 per dose in the U.S. | 01:39 |
| LjL | Shingrix for 5 bucks? | 01:40 |
| specing | Maybe I should plan a vaccination trip to albania or something | 01:40 |
| LjL | i'm not entirely sure Albania counts as a poor country | 01:41 |
| specing | LjL: the what | 01:41 |
| nixonix | %tr <fi vyöruusu | 01:41 |
| Brainstorm | nixonix, Finnish to English: shingles (Google) — Shingles (Wikipedia) | 01:41 |
| nixonix | shingrix the same? | 01:41 |
| LjL | nixonix, shingrix is one of the two vaccines available for it, the other is Zostavax | 01:41 |
| LjL | Shingrix is more efficacious although it also has more side effects | 01:42 |
| specing | 53 eur for one dose(?) of HPV vaccine (unknown which one) in my country | 01:42 |
| LjL | Zostavax is basically the Vaxzevria of shingles | 01:42 |
| specing | against HPV 6,11,16,18 | 01:42 |
| LjL | specing, are you sure you can even get it if you're not like <18? | 01:42 |
| specing | not sure, but it doesen't say that its for children only... | 01:43 |
| specing | ah, and in the news article some 23 year old student of medicine said that they recently got it | 01:43 |
| dTal | Shingrix sounds like a Chinese province | 01:44 |
| nixonix | shingavax, i like that | 01:44 |
| dTal | Zostovax, a Russian city | 01:44 |
| LjL | dTal, that totally doesn't work in chinese phonology, do you want an a/an lecture in chinese or? | 01:44 |
| nixonix | i think the Spikevax was a joke, then they after laughing started saying, yeah, why not | 01:45 |
| Cashlin | hahaha LjL keeps taking names | 01:45 |
| dTal | LjL: ...I'll be good... | 01:45 |
| Cashlin | the shing sounds chinese but the rix doesnt but you do somtimes see Xs in translations i think | 01:45 |
| LjL | Cashlin, but the x is at the start of the syllable, never at the end | 01:46 |
| LjL | dTal, (sorry you got it anyway) | 01:46 |
| Cashlin | ahhh I see, that pattern seems clear to me now | 01:46 |
| LjL | nixonix, i think there must actually be some legal intricacy behind these many names for vaccines. the latest FDA authorization covers "Pfizer COVID-19 vaccine" and "Comirnaty" separately, as separate products, with then a sidenote saying they don't differ in composition, safety or efficacy | 01:47 |
| LjL | https://www.fda.gov/media/150386/download | 01:48 |
| nixonix | it might be due to changed manufacturing process, which needs to be approved. novavax had problems with FDA when they changed it from ... possibly what they used for those in trials or something | 01:49 |
| LjL | nixonix, but in Europe it's been Comirnaty for a much longer time already | 01:50 |
| LjL | "Pfizer-BioNTech COVID‑19 Vaccine contains a nucleoside-modified messenger RNA (modRNA) encoding the viral spike (S) glycoprotein of SARS-CoV-2 formulated in lipid particles. COMIRNATY (COVID-19 Vaccine, mRNA) is the same formulation as the Pfizer- BioNTech COVID-19 Vaccine and can be used interchangeably with the Pfizer-BioNTech COVID-19 Vaccine to provide the COVID-19 vaccination series.8 | 01:50 |
| LjL | 8 The licensed vaccine has the same formulation as the EUA-authorized vaccine and the products can be used interchangeably to provide the vaccination series without presenting any safety or effectiveness concerns. The products are legally distinct with certain differences that do not impact safety or effectiveness. | 01:50 |
| LjL | "certain differences" | 01:51 |
| LjL | i'd have a youtube video to link about "certain differences" if they hadn't taken it down arbitrarily ;( | 01:51 |
| specing | ingreedients contain more legalese | 01:51 |
| nixonix | besides manufacturing possibly, they changed the cold chain requirements. maybe nothing changed in the product and they just found that warmer was ok, or then they changed something | 01:52 |
| nixonix | eg mrna synthesis may have been swapped to something that is more effective | 01:53 |
| nixonix | they improved production on some european plants, and eu approved it. maybe they just added more production lines, or then improved the old ones | 01:55 |
| nixonix | .title https://twitter.com/fitterhappierAJ/status/1433510902259666948 | 01:56 |
| Brainstorm | nixonix: From twitter.com: Anthony J Leonardi, PhD, MS (@fitterhappierAJ): "2 months isnt even enough time for repeat animal challenge studies. it's too fast and the returns diminish like the titers" | nitter | 01:56 |
| nixonix | some things to consider when wondering why not delta spike yet | 01:57 |
| LjL | i'm not really wondering myself | 01:57 |
| LjL | 1) it takes time 2) Pfizer wants to make money | 01:57 |
| LjL | more* money | 01:57 |
| LjL | Moderna started working and trialling a Beta vaccine several months ago | 01:58 |
| LjL | are they being paid off? no, maybe they won't even end up using it, as now Beta seems inconsequential in the west | 01:58 |
| LjL | and in any case, the trial isn't done yet, even though unlike Pfizer, they started a while ago | 01:58 |
| nixonix | what if beta spike is pretty good vs delta, but delta spike isnt that good vs beta. then it beta, gamma or something new starts to take over, among those with partial immunity, like i envisioned earlier | 02:00 |
| nixonix | curse you net split! | 02:00 |
| LjL | in fact i think Moderna did try pointing out that their Beta vaccine elicits high titers for Delta | 02:01 |
| LjL | i'm sure they don't want to just have wasted the effort | 02:01 |
| LjL | and hey maybe they're right and it works fine, but i'm not sure how rationally vaccine decisions are going to be taken as the landscape gets more complex | 02:02 |
| LjL | the 3rd booster in the US already seems like a mess, if i am to listen to Topol | 02:02 |
| nixonix | but they have much more information than we. im sure they think their best whats the most profitable | 02:03 |
| LjL | quite | 02:05 |
| de-facto | do we have numbers for how many of the PCR positive do seroconversion? | 02:17 |
| de-facto | does it depend on age? | 02:17 |
| LjL | we don't really, given that study published by the CDC cited three different studies with *widely* different seroconversion rates (and it's itself only a small study) | 02:20 |
| de-facto | asking because of tested or vaccinated or recovered, and i guess recovered means from having had a positive PCR test | 02:21 |
| Brainstorm | New from r/WorldNews: worldnews: 'I wish we didn't have to do this': Alberta to offer $100 incentive to get vaccinated against COVID-19 → https://is.gd/0HMIEv | 02:22 |
| LjL | de-facto, well, on the other hand, you might not get meaningful seroconversion from a vaccine either, for various reasons... and yet they give you a certificate without testing your antibodies first | 02:22 |
| de-facto | so they not only equate those that once had a positive PCR test with those that were vaccinated, they also ignore reinfections and breakthrough infections in Germany right now | 02:22 |
| de-facto | so pretty much everything about that is wrong imho | 02:23 |
| de-facto | but i think the seroconversion rates from vaccines are much more reliable | 02:23 |
| nixonix | yeah | 02:23 |
| nixonix | it seems from mild or nonsymptomatic infection its not nearly 100% for IgG. at least more than minimal | 02:24 |
| nixonix | hard to say, because many mild or nonsymptomatic are never found | 02:24 |
| de-facto | and also very young, i heard they can just kill it without even seroconverting | 02:25 |
| nixonix | and do they produce IgA, IgM, cellular immunity, and if, how about is it infection + 1 dose still good protection, or do they need 2? | 02:25 |
| de-facto | but if they are found, lets say with routine testing PCR, then they are counted as cases, seroconversion is assumed and they are treated like they would have been vaccinated | 02:25 |
| de-facto | no testing anymore, and assuming they can not get reinfections | 02:26 |
| de-facto | that is just plain wrong imho | 02:26 |
| nixonix | topol just wrote that infection and one dose is the best protection there is. but how about if not seroconverting. those are the gray area cases, did they have some systemic infection, or just in mucosal | 02:26 |
| LjL | "recovered" as a valid certificate was probably a bad idea anyway since there are now "COVID chasers" who try hard to get it just so they can obtain the certificate without a vaccine | 02:27 |
| nixonix | if found in pcr, it doesnt mean they had systemic infection and much protection necessarily. they just had some viral load in upper respiratory | 02:27 |
| de-facto | they should get tested for seroconversion, e.g. if they carry antibodies and if low get an additional vaccine dose, then tested again if antibody levels are similar to two vaccine shots | 02:28 |
| de-facto | or: they should just get vaccinated as everyone else | 02:28 |
| de-facto | and everybody, regardless of any seroconversion status should get tested | 02:28 |
| LjL | and also we shouldn't go anywhere at any time for any reason whatsoever | 02:29 |
| nixonix | those hospitalized have a good seroconversion rate | 02:30 |
| nixonix | was it in that jap study or what was it. or danish | 02:31 |
| de-facto | yeah of course | 02:31 |
| de-facto | because symptomatic infections or even hospitalized have a very strong immune reaction | 02:31 |
| de-facto | but what about those that got tested positive but have super mild or even asymptomatic infection? | 02:32 |
| nixonix | https://www.science.org/doi/10.1126/sciadv.abj5365 | 02:32 |
| nixonix | page 4 | 02:32 |
| de-facto | so vaccinated have similar neutralization compared with hospitalized infections | 02:33 |
| nixonix | and imo you need around 150 neut id50 to (still) have a decent protection for infection | 02:34 |
| de-facto | non-hospitalized infecitons scatter over a very wide range | 02:34 |
| nixonix | better. hospitalized vs vacc | 02:35 |
| nixonix | yeah, its a crapshoot | 02:35 |
| nixonix | so if i would have got infection before vax, id taken the 1st dose maybe 2-3 months after cured (depending on current risk), then the 2nd just 3 months later prob. or 2 if very mild symptoms | 02:36 |
| nixonix | given choice | 02:36 |
| de-facto | yeah would make sense | 02:37 |
| nixonix | anyways, these few recent papers, quatar, both danish, the one above, are the best we have for now, to estimate the protection, shares of those not seroconverting etc. worth saving | 02:39 |
| nixonix | and that on us hcw was it, while not representative sample which must be considered (36% something) | 02:40 |
| nixonix | that refd to the german study with 85% | 02:41 |
| nixonix | lots of interesting little papers have come out recently, with bits of information that can be combined | 02:43 |
| de-facto | yes indeed | 02:44 |
| nixonix | .title https://www.medrxiv.org/content/10.1101/2021.07.05.21260050v2.full - on lethality too, like this one | 02:46 |
| Brainstorm | nixonix: From www.medrxiv.org: Progressive Increase in Virulence of Novel SARS-CoV-2 Variants in Ontario, Canada | medRxiv | 02:46 |
| de-facto | uff so those numbers really say it becomes *more* aggressive not less (as many like to wishfully repeat without looking at data) | 02:49 |
| de-facto | "Results Compared to non-VOC SARS-CoV-2 strains, the adjusted elevation in risk associated with N501Y-positive variants was 59% (49-69%) for hospitalization; 105% (82-134%) for ICU admission; and 61% (40-87%) for death." | 02:49 |
| de-facto | "Increases with Delta variant were more pronounced: 120% (93-153%) for hospitalization; 287% (198-399%) for ICU admission; and 137% (50-230%) for death." | 02:49 |
| de-facto | "The progressive increase in transmissibility and virulence of SARS-CoV-2 VOCs will result in a significantly larger, and more deadly, pandemic than would have occurred in the absence of VOC emergence." | 02:50 |
| LjL | what do you think about this comment https://disqus.com/embed/comments/?base=default&f=medrxiv&t_i=node%2F380177&t_u=https%3A%2F%2Fwww.medrxiv.org%2Fcontent%2F10.1101%2F2021.07.05.21260050v2&t_e=Progressive%20Increase%20in%20Virulence%20of%20Novel%20SARS-CoV-2%20Variants%20in%20Ontario%2C%20Canada&t_d=Progressive%20Increase%20in%20Virulence%20of%20Novel%20SARS-CoV-2%20Variants%20in%20Ontario%2C%20Canada&t_t=Progressive%20Increase%20in%20Virulence%20of%20Novel%20SAR | 02:52 |
| LjL | S-CoV-2%20Variants%20in%20Ontario%2C%20Canada&s_o=default# | 02:52 |
| LjL | good lord | 02:52 |
| LjL | the second comment at https://www.medrxiv.org/content/10.1101/2021.07.05.21260050v2.full | 02:52 |
| LjL | and the paper it refers to, with an abstract that's not saying much https://www.medrxiv.org/content/10.1101/2021.07.29.21261317v1 | 02:52 |
| LjL | which is supposedly from israel's sort-of-unanalysed data | 02:52 |
| nixonix | yeah, they all lack adjustment for confounders. the danish: https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(21)00580-6/fulltext | 02:57 |
| de-facto | .title https://www.medrxiv.org/content/10.1101/2021.08.30.21262446v1 | 02:58 |
| Brainstorm | de-facto: From www.medrxiv.org: Effectiveness of COVID-19 Vaccines Against SARS-CoV-2 Infection During a Delta Variant Epidemic Surge in Multnomah County, Oregon, July 2021 | medRxiv | 02:58 |
| nixonix | how about comparing hospitalization rates among kids, not eligible for vaccines yet (vs previous variants): | 03:08 |
| nixonix | .title https://twitter.com/EricTopol/status/1433857194223493129 | 03:08 |
| Brainstorm | nixonix: From twitter.com: Eric Topol (@EricTopol): "The other @CDCgov report today in kids; impact of Delta and vaccinations in adolescents https://www.cdc.gov/mmwr/volumes/70/wr/mm7036e2.htm?s_cid=mm7036e2_w" | 42l - nitter | 03:08 |
| specing | Do kids get long covid? | 03:09 |
| LjL | i am perplexed on whether to add https://www.medrxiv.org/content/10.1101/2021.07.05.21260050v3 to Zotero as the comments are kind of critical | 03:09 |
| LjL | they apparently didn't even know which of the cases were vaccinated | 03:09 |
| LjL | how do you make a model without that | 03:10 |
| LjL | meanwhile over in ##virology the bot spits out more papers in the time it takes me to (not) roughly evaluate one, lol | 03:10 |
| LjL | and by "lol" i mean i feel overwhelmed and will drink alcohol | 03:12 |
| nixonix | what was the mean or median time from 2nd dose in that oregon study? | 03:14 |
| Brainstorm | New from r/WorldNews: worldnews: C.1.2 variant: New coronavirus strain has highest mutation rate yet, study says → https://is.gd/1sbIO9 | 03:15 |
| nixonix | around 100 days. a bit over 3 months. i told you, its a 4 months vax | 03:15 |
| nixonix | so it was significantly reduced only for minority | 03:16 |
| LjL | well i can't see how it would be sustainable to vaccinate the entire population every 4 months | 03:17 |
| nixonix | 5 months would be better than 6 | 03:17 |
| LjL | err, why? | 03:18 |
| nixonix | but if they want to burn it through unvaccinated kids, i think the adults doing that deserve some ICU time for that... | 03:18 |
| nixonix | less breakthroughs from 4->5 months than ->6 | 03:19 |
| nixonix | but it isnt sustainable solution, and maybe mrna manufacturers cant produce new doses for all every 4 or 5 months. so something more lasting is needed. and also, the more there are partly protected, those with waned protection, the more chances that something like SA variant or P.1 will take over | 03:21 |
| nixonix | theres supposedly a finnish paper coming out, that found 2*pfizer a bit better than az+pfizer. only a finnish press release out yet. but small samples idk if it will bring anything that matters | 03:25 |
| Brainstorm | New from r/WorldNews: worldnews: Oscar De La Hoya hospitalized with Covid-19 days before his return to the boxing ring → https://is.gd/6IV1uw | 03:26 |
| nixonix | .title https://www.theguardian.com/world/2021/aug/23/what-does-getting-covid-feel-like-for-the-fully-vaccinated | 03:27 |
| Brainstorm | nixonix: From www.theguardian.com: What does getting Covid feel like for the fully vaccinated? | Coronavirus | The Guardian | 03:27 |
| LjL | Simon Price, 54, a local government employee from Abingdon, Oxfordshire, thinks he caught the virus when he attended the Euros semi-final game between England and Denmark at Wembley stadium in July. | 03:29 |
| LjL | “I’ve worked religiously from home and took a bit of personal pride in being very cautious to protect my family since the pandemic began. Wembley was the only place I’ve visited apart from shops and the office on a couple of occasions in June. I hadn’t been socialising otherwise. | 03:29 |
| LjL | groan | 03:29 |
| LjL | "religiously" "pride" "very cautious" | 03:30 |
| LjL | and goes to a stadium | 03:30 |
| LjL | people just don't get it do they | 03:30 |
| LjL | McGuire, a real estate project manager, is unsure about whether it was wise to socialise at a mass event at a time when the Delta variant was spreading rapidly. “I guess if you’ve got that many people together, even if outdoors, there’s always a risk that someone will get Covid. | 03:31 |
| LjL | damn this one is smart | 03:31 |
| LjL | anyway this article is rubbish, it almost doesn't say anything about the "question" in the headline | 03:32 |
| nixonix | it included 3.7M people, but hospitalization numbers werent that big, so idk. 7 days post 2nd dose results (end of apr to mid august): VE vs "infection" (identified), 78% for all az, pfizer and moderna, combination az+mrna it was 80% | 03:34 |
| nixonix | vs hospitalization: both mrna vaxes 97%, az 93%, az+mrna 91% | 03:35 |
| LjL | i figure we'll have to see the confidence intervals | 03:35 |
| LjL | if they're widely overlapping it might not mean much, we've already seen that with other studies | 03:36 |
| nixonix | mixed variants. strange result those hospitalizations might be variance due to low numbers | 03:36 |
| nixonix | az use was reduced in the spring more than in most of europe | 03:37 |
| nixonix | i dont know if they adjusted for age groups, time from 2nd dose or anything | 03:38 |
| twomoon | hello | 03:41 |
| LjL | this is an... interesting account (all tweets considered) that Balloux retweeted https://twitter.com/NahasNewman | 03:44 |
| LjL | and by interesting i mean perplexing | 03:44 |
| twomoon | what's curious about that twitter account? | 03:53 |
| twomoon | t.co/GXY38NRmaB?amp=1 <-- this ? | 03:53 |
| LjL | no | 04:00 |
| LjL | what's curious is it seems to be, almost in its entirety, an anti-mask and in particular anti-mask-in-schools account | 04:00 |
| LjL | then i also find https://twitter.com/MichaelPSenger/status/1432753095046356994 linked from there, which certainly makes one feel uneasy | 04:00 |
| LjL | but then i look at THAT account and its profile describes it as "Attorney, author of China’s Global Lockdown Propaganda Campaign" | 04:00 |
| dTal | hell of a resume | 04:01 |
| twomoon | what does that even mean | 04:02 |
| dTal | means he wrote this https://www.tabletmag.com/sections/news/articles/china-covid-lockdown-propaganda | 04:02 |
| LjL | scan through the (re)tweets and you should roughly find out, twomoon | 04:02 |
| LjL | all the replies are all about how this is an organized operation by worldwide government and/or China alone | 04:03 |
| LjL | but i got there by following (presumably supportive) retweets by Balloux, who considers himself a "militant corona-centrist", and who also is prominent | 04:03 |
| LjL | i don't know if he's a corona-centrist, but if he is, he certainly seems to be into the art of making moderation extreme | 04:04 |
| dTal | wow, according to the twitter sidebar, "Eating a Single Hot Dog May Take 36 Minutes Off Your Life, Study Says" | 04:04 |
| dTal | I guess, if it's an especially large or messy hot dog... | 04:04 |
| LjL | dTal, that's funny, people in... uh, ##biology i think were talking about how terrible hot dogs were just a bit ago | 04:04 |
| dTal | it's the invisible hand of the memesphere at work LjL | 04:05 |
| nixonix | social aspects are complex in this epidemic, but so are immunological and virological. i read some leonardi's old tweets. he seemed to support t-cells matter most (for severe i think), but changed his mind. not sure if it was that preprint i wrote on july 2020 on orf8 grapping antigen presenting mhc-I | 04:06 |
| nixonix | which has got more attention lately. not sure if its confirmed, but not forgotten obviously. meaning, killer t-cells cant find infected cells | 04:07 |
| nixonix | .title https://twitter.com/fitterhappierAJ/status/1323471775611670528 | 04:07 |
| Brainstorm | nixonix: From twitter.com: Anthony J Leonardi, PhD, MS (@fitterhappierAJ): "cov2 is different, it hides from t cells with orf8 while it loads a superantigen on spike. it's an impressive virus and also gets rid of t reg cells- [...] | 04:07 |
| rpifan | the current covid? | 04:10 |
| nixonix | i think it was in wuhan 1.0 already | 04:10 |
| nixonix | syncytia (which then can kill t-cells, according to leonardi, idk) is enhanced with - was it P681R i think. which also accelerates plasma mebrane fusion in normal cell entrance | 04:12 |
| nixonix | superantigen is around PRRAR motif, and supposedly is similar than some bacterial toxins and snake venoms, making killer t-cells crazy, so they can attack any adjacent cells, be responsible in different tissue intiltration like brain, heart etc | 04:14 |
| nixonix | if true, idk if it is | 04:14 |
| nixonix | that is the furin cleavage site | 04:15 |
| nixonix | modified in novavax and possibly jnj. so if it has something to do with heart inflammation (just my idea, that it could have), those wouldnt then cause that, via that mechanism | 04:16 |
| nixonix | that i wrote *about | 04:19 |
| nixonix | leonardis tweets have lots of information, but its pretty compressed | 04:21 |
| nixonix | watching what happens in australia, or used to happen in hard hit and hard lockdown countries, idk because i havent experienced anything like that. i feel like we are mostly by-standers watching and wondering, like the main character in camuses the stranger | 04:29 |
| nixonix | rogan got negative from rona test today. lets see if he reports some lc stuff later or not | 04:52 |
| nixonix | .title https://nypost.com/article/famous-anti-vaxxers-who-suffered-from-covid/ | 04:52 |
| Brainstorm | nixonix: From nypost.com: Famous anti-vax media personalities who got COVID | 04:52 |
| nixonix | in nz cases went down again, now 22. in aus, more up, around 1520 in nsw and 190 in victoria | 04:57 |
| nixonix | .title https://www.dailymail.co.uk/news/article-9956419/Shock-JCVI-experts-decide-NOT-recommend-Covid-jabs-healthy-children-aged-12-15.html in uk prob loud and rude arguing coming | 05:02 |
| Brainstorm | nixonix: From www.dailymail.co.uk: Shock as JCVI experts decide NOT to recommend Covid jabs for healthy children aged 12 to 15 | Daily Mail Online | 05:02 |
| nixonix | Children 'will be jabbed from next week': Government expects Chris Whitty to green light vaccines despite JCVI experts' refusal to back mass immunisation for 12 to 15-year-olds | 05:03 |
| Brainstorm | New from Eric Topol: @EricTopol: On a US Delta wave day when there were more than 2,000 deaths and 190,000 new cases, the "only" positive thing was that hospitalizations didn't increase (actually when down a bit), sitting at a ~100,000 plateau → https://is.gd/CG0bRC | 05:34 |
| Brainstorm | New from The Indian Express (Health): Health: Effective ayurvedic tips to recover from long covid → https://is.gd/6eKbgN | 05:45 |
| Brainstorm | New from BBC Health: Covid-19: Final decision on jabs for children due in days: There is a "strong case" for vaccinating healthy 12 to 15-year-olds, the government believes. → https://is.gd/XkFrTH | 06:27 |
| Brainstorm | New from The Indian Express: World: New Zealand reports first death from Delta variant of COVID-19 → https://is.gd/8b7d8F | 06:59 |
| Brainstorm | New from The Indian Express: World: US administers 373.5 mln doses of COVID-19 vaccines: CDC → https://is.gd/vEkabi | 07:52 |
| Brainstorm | New from The Indian Express: World: US COVID-19 booster shot campaign to start with only Pfizer: source → https://is.gd/U9vYge | 08:13 |
| Brainstorm | New from The Indian Express: World: FDA pushes for Moderna booster shot data in weighing dose → https://is.gd/ZaxTc1 | 08:44 |
| Brainstorm | New from r/Coronavirus: Daily Discussion Thread | September 04, 2021: Please refer to our Wiki for more information on COVID-19 and our sub. You can find answers to frequently asked questions in our FAQ , where there is valuable information such as our: → https://is.gd/4kjfQ9 | 09:05 |
| Pepe[m]1 | Hello | 10:06 |
| Brainstorm | New from Reddit (test): China_Flu: I'm a local ICU doctor. Please take precautions, COVID-19 is going to hit our hospitals hard → https://is.gd/GalHwb | 10:08 |
| Brainstorm | New from The Indian Express: World: Moderna seeks EU authorization for COVID-19 vaccine booster dose → https://is.gd/uehyqc | 11:00 |
| Brainstorm | New from The Indian Express: World: White House seeks $65 billion for ‘Apollo’ plan to prepare for future pandemics → https://is.gd/0wQOmO | 11:11 |
| Brainstorm | New from Il Sole 24 Ore: Green pass, perché ora vale per 12 mesi e quanto dura la protezione del vaccino: Il Parlamento ha appena allungato di 3 mesi la vita dei certificati verdi. Ma al momento non esistono certezze sulla durata della protezione del vaccino → https://is.gd/86arRB | 12:04 |
| Brainstorm | New from Reddit (test): CoronaVirus_2019_nCoV: Moderna Wraps Up Covid Booster Filing, Setting Up FDA Review → https://is.gd/oQmFPk | 12:35 |
| Brainstorm | New from r/WorldNews: worldnews: Malaysia appoints former PM to lead coronavirus recovery council → https://is.gd/zcg04a | 12:57 |
| Brainstorm | New from NPR: Poison Control Centers Are Fielding A Surge Of Ivermectin Overdose Calls: The nation's poison control centers saw a 245% jump in reported exposure cases from July to August as more people take the anti-parasite drug that some falsely claim treats COVID-19. → https://is.gd/oWNTyK | 13:07 |
| specing | kek | 13:08 |
| Brainstorm | New from The Indian Express: World: New Zealand reports first death linked to Pfizer/BioNTech COVID-19 vaccine → https://is.gd/rwPmEJ | 13:39 |
| Brainstorm | New from Retraction Watch: Weekend reads: A deep dive into a problematic study of ivermectin; how journals respond to allegations; prison and now scrutiny: Before we present this week’s Weekend Reads, a question: Do you enjoy our weekly roundup? If so, we could really use your help. Would you consider a tax-deductible donation to support Weekend [... want %more?] → https://is.gd/4ZfJkE | 14:10 |
| Brainstorm | New from The Indian Express: World: Philippines lifts travel ban on India, 9 other countries amidst rise in Covid-19 → https://is.gd/VvhvWu | 14:53 |
| Brainstorm | New from Eric Topol: @EricTopol: R to @EricTopol: Links to the 2 studies reported this week on the difference in antibody response → https://is.gd/RXJOHE | 15:35 |
| Brainstorm | New from Eric Topol: @EricTopol: Pediatric covid hospitalizations by state fully vaccination per cent, past 30 dayshttps://time.com/6092446/pediatric-covid-19-surge/ by @Jamie_Ducharme @TIMEHealth Florida, an off-the-chart outlier → https://is.gd/FNbnxK | 16:07 |
| Lunita | Are there any articles about less sides effects of you wait longer in between doses? | 16:29 |
| Lunita | Of the vaccine that is | 16:29 |
| xrogaan | Lunita: why do you believe that a longer span of time between the two shots would lessen the side effects? | 16:56 |
| xrogaan | why would you believe* | 16:56 |
| xrogaan | that is, what information would lead you to believe that? | 16:57 |
| Lunita | I saw some articles and people speaking about it but didn't know for sure. There were also articles saying waiting longer can actually boost your immunity. | 17:03 |
| Xenguy | I saw the latter certainly | 17:04 |
| xrogaan | From what I understand, adverse effects are dependent on your own metabolism. That is, how you react to the foreign stuff injected into you. | 17:04 |
| foo | What is the probability of getting long-covid? Do we have a stat on that? | 17:05 |
| xrogaan | Some people experience no adverse effects, other are hammered. | 17:05 |
| Vall | Lunita: these two claims seem contradictory to me. I mean, stronger immunity (ie, stronger immune system reaction) would mean *more* side effects, not less. | 17:05 |
| Vall | foo: I saw an article stating something like 50%. | 17:05 |
| xrogaan | Lunita: what I know for sure is that heterogeneous vaccination raise your immunity. That means getting two shots of different vaccine. | 17:06 |
| Xenguy | (I keep wondering if blood type is a relevant factor in the context of COVID, but I've seen nothing written about that angle) | 17:06 |
| xrogaan | not at the same time, the two shots. | 17:07 |
| Lunita | Vall: I wouldn't mind the flu like symptoms I guess I'm more concerned about the crazy ones. I got the first shot and was just a little tired. Not sure how the 2nd will feel. | 17:07 |
| Vall | xrogaan: or 2 shots of one vaccine, followed by a 3rd from a different one (there was a govmt published in England about that, giving a 3rd dose of pfizer to people who had taken 2 of Astrazeneca) | 17:08 |
| Lunita | xrogaan: has there been anything written about how safe that is? And would you get the same side effects? | 17:08 |
| Xenguy | xrogaan, Interesting, that is what happened to me (totally an accident) | 17:08 |
| Vall | Lunita: crazy by its very definition, is hard to prevent/protect against. | 17:08 |
| foo | Xenguy: yes, blood type matters. | 17:09 |
| Vall | Lunita: the best thing, I think, is to work with probabilities. Crazy means very little probability, so I would not concern me with that. | 17:09 |
| foo | Xenguy: at least, I've seen various reports on O blood type handling it better than A blood type. | 17:10 |
| Xenguy | foo, I'd love to read more about this angle, if it is relevant at all | 17:10 |
| Lunita | Vall: I see. Wish I was a kid again. My kid is fully vaccinated and had zero symptoms with both doses lol | 17:10 |
| Xenguy | foo, Oh yes, that rings a bell now | 17:10 |
| Vall | foo: I've seen those too. But I think it was discussed in the context of COVID19 recovery prognosis, not long-COVID. | 17:10 |
| foo | I wonder if there's any chance of the vaccine negatively affecting the immune system's ability to naturally fight of infections in the long-term? | 17:11 |
| foo | Vall: oh, was the blood-type question related to long covid? I didn't consider that | 17:11 |
| Xenguy | Lunita, For me, the 2nd jab hit harder, but really I just felt a little week for a day or so, and then I was fine again. | 17:11 |
| Vall | Lunita: LOL don't we all? :-) But then I remember being woken up at 6AM to go to school, never having serious money, never getting laid, etc ;-) | 17:11 |
| Lunita | Xenguy: Which one did you have? | 17:11 |
| Lunita | Vall: lolol yeah there's that too | 17:12 |
| Xenguy | Lunita, Pfizer first, Moderna second | 17:12 |
| Lunita | And they will do they for you? | 17:13 |
| foo | Xenguy: did you ready that that was better than 2x Pfizer or 2x Moderna? | 17:13 |
| foo | s/ready/reda | 17:13 |
| foo | read | 17:13 |
| Vall | Xenguy, Lunita: I got 2 doses of Pfizer. After 1st one, just some pain in the injection site. After 2nd, I felt really strange (like, spaced out) for a day, and then nothing (except injection pain site for a day or 2). Wife was the same after 1st dosis, but stayed down for 2 days with fever and tiredness. | 17:13 |
| Xenguy | Lunita, It was random (just what was available at the time) | 17:13 |
| Lunita | I wonder if they would do that by request | 17:14 |
| Vall | PS: for what it's worth, my blood is type A and wife's is type O | 17:14 |
| foo | I'd be curious if anyone hasn't been vaccinated here and is skeptical (but not strong anti-vax) - feel free to PM me. | 17:15 |
| Xenguy | foo, There were a small number of articles that suggested 2 different vaccines might be more effective, but I don't know for sure | 17:15 |
| foo | Xenguy: yeah, I thought I saw that too | 17:15 |
| Vall | folks, gotta go (some errands to run here). Will be back later, ciao y'all | 17:15 |
| Xenguy | Ciao | 17:16 |
| LjL | foo, the blood type stuff is a bit dated, i don't have anything specific to show right now, but from hearsay, those studies have been discredited | 17:42 |
| Brainstorm | New from Reddit (test): CoronavirusUK: Saturday 04 September 2021 Update → https://is.gd/n8coCi | 17:42 |
| foo | LjL: oh, thank you. | 17:46 |
| xrogaan | Yes, there was something written about heterogeneous vaccination. | 18:01 |
| foo | Would you say that the vaccines of today address the underlying pathology of the virus or only the symptoms? | 18:36 |
| LjL | they create antibodies that actively stop the virus from entering cells and reproducing. they do it imperfectly with Delta, and maybe even with prior variants in the airways, but to the extent they do, they definitely go to the root of what the virus does | 18:37 |
| foo | LjL: thank you, that might be one of the simplest explanations I've seen | 18:40 |
| Brainstorm | New from Eric Topol: @EricTopol: The latest on mask efficacy from the randomized trial of policy in 350,000 people from 600 villages in Bangladeshhttps://www.theatlantic.com/ideas/archive/2021/09/masks-were-working-all-along/619989/ by @DKThomp @TheAtlantic https://www.economist.com/graphic-detail/2021/09/03/real-world-evidence-shows-face-masks-reduce-covid-19s-spread → https://is.gd/xJPsWY | 18:46 |
| LjL | funny, i read about that Bangladesh experiment yesterday, except from those Twitter accounts that Balloux's retweet led me to, and they were, of course, using the same results to conclude that masks *don't* work (and wondering how come if there is any effect, it's only in people older than 50) | 18:52 |
| Brainstorm | New from Eric Topol: @EricTopol: R to @EricTopol: The immune response for Prior Covid plus 1-dose vaccine (hybrid immunity) has not been beaten or matched by any 2-dose vaccine or mix/match combination to date. → https://is.gd/JVeZpG | 19:18 |
| Brainstorm | New from Reddit (test): COVID19: Simulated Sunlight Rapidly Inactivates SARS-CoV-2 on Surfaces → https://is.gd/IPxUW7 | 20:00 |
| -Bridgestorm- 🌒 انفجار? زلزال? Earthquake? Likely strong tremor, with 54 reports, possibly occurred 12 minutes ago (18:29:29 UTC), with a crescent moon, Dhahran, Saudi Arabia (26.36, 50.13) ± 6 km likely felt 30 km away by 100 people (Twitter) | 20:42 | |
| Brainstorm | New from Eric Topol: @EricTopol: R to @EricTopol: To date, there are limited clinical data for Moderna vaxx waning. The UCSD HCW study this week did not report their data split out by Pfizer (55%), Moderna (45%) vaccines, but the results for symptomatic infections were similar. If we had national US data we would know now. → https://is.gd/vhId8s | 21:25 |
| Brainstorm | New from r/WorldNews: worldnews: Covid: Call for clarity on vaccines for children → https://is.gd/JZvuln | 21:35 |
| Brainstorm | New from Eric Topol: @EricTopol: Having it 2-ways on boostersThe primary endpoint for the large, placebo-controlled covid vaccine trials was symptomatic infections (SI), a proxy for hospitalizations/deaths (H/D)With a Pfizer reduction of protection for SI at 6 months, many argue that H/D will not be affected → https://is.gd/8CaaPz | 21:57 |
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