| nixonix | .title https://www.medrxiv.org/content/10.1101/2021.10.01.21264349v1?rss=1 | 00:01 |
|---|---|---|
| Brainstorm | nixonix: From www.medrxiv.org: Humoral cross-reactivity towards SARS-CoV-2 in young children with acute respiratory infection with low-pathogenicity coronaviruses | medRxiv | 00:01 |
| nixonix | "Convalescent sera from these samples had antibodies against the respective seasonal CoVs .. Forty serum samples showed no significant neutralization of SARS-CoV-2, while 2 samples showed inconclusive results. These findings suggest that the antibodies generated in low-pathogenicity coronavirus infections offer no protection from SARS-CoV-2 | 00:02 |
| nixonix | infection in young children | 00:02 |
| nixonix | but instead you can get some nasty interference, like OAS or ADE even... | 00:03 |
| nixonix | or, you can get it other way, with that awesome natural infection (as a primary immunization, or instead of booster, after some vax doses), when you encounter some hcovs later | 00:06 |
| nixonix | or some novel zoonosis ronas in the future | 00:06 |
| Brainstorm | Updates for Rwanda: +89 cases (now 97870), +2 deaths (now 1283), +30863 tests (now 2.9 million) since 21 hours ago — Bahrain: +62 cases (now 275237), +16923 tests (now 6.5 million) since a day ago — Mali: +9 cases (now 15287), +2598 tests (now 423361) since a day ago | 00:09 |
| nixonix | you saying, it was just kids? "In another study, none of the 37 pre-pandemic sera with prior low-pathogenicity coronavirus infection showed cross-neutralization of SARS-CoV-2 [3]" | 00:11 |
| nixonix | .title https://academic.oup.com/cid/article/73/5/e1208/6017810 | 00:21 |
| Brainstorm | nixonix: From academic.oup.com: Absence of Severe Acute Respiratory Syndrome Coronavirus 2 Neutralizing Activity in Prepandemic Sera From Individuals With Recent Seasonal Coronavirus Infection | Clinical Infectious Diseases | Oxford [...] | 00:21 |
| nixonix | One mechanism by which pre-existing cross-reactive antibodies might influence the course of SARS-CoV-2 infection is ADE. Therefore, we investigated the potential ADE of the three cross-reactive Abs using a SARS-CoV-2 live virus assay (Fig. 4c). Of the three cross-reactive antibodies, | 00:29 |
| nixonix | CC9.3 mAb showed a marginal increase (twofold) in infection of SARS-CoV-2 virus in the FcγRIIa (K562) and FcγRIIb (Daudi) expressing target cells that can mediate ADE. Further in vivo assessment would be needed to determine whether this activity is associated with any meaningful physiological effects | 00:30 |
| nixonix | .title https://www.nature.com/articles/s41467-021-23074-3 | 00:31 |
| Brainstorm | nixonix: From www.nature.com: Cross-reactive serum and memory B-cell responses to spike protein in SARS-CoV-2 and endemic coronavirus infection | Nature Communications | 00:31 |
| Brainstorm | New from r/WorldNews: worldnews: NSW reports ‘dramatic drop’ in new Covid cases as Melbourne edges closer to World’s Longest Lockdown → https://is.gd/MJfjpi | 00:33 |
| Brainstorm | Updates for Namibia: +48 cases (now 127804), +1 deaths (now 3516), +1493 tests (now 708982) since a day ago | 00:34 |
| nixonix | singapore dorm areas have had way longer lockdown | 00:39 |
| nixonix | .title https://twitter.com/DrEricDing/status/1444793275374788613 includes article link | 00:43 |
| Brainstorm | nixonix: From twitter.com: Eric Feigl-Ding (@DrEricDing): "📍Pregnancy & #COVID19—“The #DeltaVariant in unvaccinated pregnant patients is one of the most horrifying disease processes I’ve ever seen. My heart is broken. Families [...] | 00:43 |
| nixonix | "In anticipation of the results from MOVe-OUT, Merck has been producing molnupiravir at risk. Merck expects to produce 10 million courses of treatment by the end of 2021, with more doses expected to be produced in 2022." | 00:47 |
| nixonix | about mutagenicity, yanks bought 1.7M doses for 1.2B in june. they likely knew by then that mutagenicity is not a big problem, or then the deal was conditional that they can show it later. you would think so, anyway... | 00:51 |
| nixonix | .title https://www.medrxiv.org/content/10.1101/2021.10.01.21264371v1?rss=1 in this study, neut titers waned faster for moderna, but they had a bit lesser share of "negative responders" who fade below the cut-off | 01:03 |
| Brainstorm | nixonix: From www.medrxiv.org: COVID-19 Neutralizing Antibody Surveillance Testing for Fully Vaccinated Individuals During Delta Variant Spread | medRxiv | 01:03 |
| nixonix | another study has found the waning rate being similar, though (meaning moderna would stay higher) | 01:04 |
| Brainstorm | New from r/WorldNews: worldnews: PwC diversity executives mocked Chinese accents, dressed as 'bat from Wuhan' during company trivia event → https://is.gd/XmhTYl | 01:04 |
| Brainstorm | Updates for Colombia: +1413 cases (now 5.0 million), +29 deaths (now 126401), +31132 tests (now 25.7 million) since 23 hours ago — Sint Maarten: +14 cases (now 4321), +11596 tests (now 53105) since a day ago — Faroe Is.: +7 cases (now 1217), +1028 tests (now 435000) since a day ago — Gibraltar: +7 cases (now 5573), +400 tests (now 363591) since a day ago | 01:11 |
| Brainstorm | New from r/Science: science: New Blood Tests Detect Cancer Easier and Earlier → https://is.gd/QCOK6v | 01:25 |
| Brainstorm | New from COVID tweets: Eric Topol (@EricTopol): Vaccination vs shingles was associated with a 32% reduced risk of Covid hospitalization in ~150,000 people age >50 compared with ~300,000 matched controls medrxiv.org/content/10.110… @KPSCALnews @KPSCalResearch pic.twitter.com/4STB5gsMjR → https://is.gd/9zvpxT | 01:36 |
| Brainstorm | Updates for Ecuador: +1381 cases (now 510619), +29 deaths (now 32791), +13928 tests (now 1.9 million) since 3 days ago — Uruguay: +61 cases (now 389185), +5204 tests (now 3.6 million) since a day ago | 01:36 |
| nixonix | .title https://www.medrxiv.org/content/10.1101/2021.10.01.21264412v1?rss=1 initial lead in race condition seems to matter | 01:58 |
| Brainstorm | nixonix: From www.medrxiv.org: Initial SARS-CoV-2 viral load is associated with disease severity: a retrospective cohort study | medRxiv | 01:58 |
| Brainstorm | Updates for Uganda: +119 cases (now 123976), +1 deaths (now 3160), +4055 tests (now 1.7 million) since a day ago — Zimbabwe: +35 cases (now 131129), +2 deaths (now 4627), +5832 tests (now 1.4 million) since a day ago | 02:01 |
| Brainstorm | Updates for Somalia: +597 cases (now 20577), +26 deaths (now 1137), +6801 tests (now 231183) since 5 days ago — Netherlands: +1632 cases (now 2.0 million) since 23 hours ago — Curacao: +17 cases (now 16609), +1 deaths (now 164), +3608 tests (now 283639) since a day ago — United Kingdom: +29682 cases (now 7.9 million) since 21 hours ago | 02:38 |
| Brainstorm | New from COVID tweets: Josiah Grindrod (@JT_Grindrod): @fitterhappierAJ So something I've been thinking about.. Feline coronavirus can infect macrophages and become FIP (but only after a mutation in the host)Is this something that SARS-COV-2 could do? Reading about long term intestine infections and macrophage infection has me midly concerned. → https://is.gd/q9ndDS | 03:00 |
| LjL | "mildly" | 03:02 |
| Brainstorm | Updates for Djibouti: +41 cases (now 12922), +2 deaths (now 171), +796 tests (now 223107) since a day ago | 03:03 |
| Brainstorm | New from COVID tweets: Eric Topol (@EricTopol): Why was Israel's 4th, Delta wave such an outlier?Contributing factors—Vaccine waning, 1st mover disadvantage—Delta's hyper-contagiousness— ~37% of total population unvaccinated —Short dose spacing (3 wks) -> less memory B & T cells— Lower dose mRNA (30 µg vs Moderna 100 µg) pic.twitter.com/HJYHM3O4Em → https://is.gd/kuaOzW | 03:22 |
| Brainstorm | Updates for Peru: +864 cases (now 2.2 million), +11 deaths (now 199457), +40778 tests (now 18.0 million) since a day ago — Paraguay: +19 cases (now 460041), +1 deaths (now 16201), +1823 tests (now 1.8 million) since a day ago | 03:40 |
| Brainstorm | Updates for Australia: +642 cases (now 113411), +8 deaths (now 1346), +162333 tests (now 38.6 million) since 2 hours ago — New Zealand: +29 cases (now 4382), +13693 tests (now 3.5 million) since 23 hours ago | 04:05 |
| Brainstorm | New from r/WorldNews: worldnews: Blood thinners can reduce COVID-19 deaths by nearly half, study finds → https://is.gd/WOgeKP | 04:15 |
| Brainstorm | New from Virology.ws: Trial By Error: BBC’s Problematic Coverage of New Long COVID Study: By David Tuller, DrPH Since the start of the coronavirus pandemic, suggesting an equivalence between COVID-19 and influenza has been a consistent approach among those seeking to downplay the current situation. So it’s not surprising to see something similar [... want %more?] → https://is.gd/5McjGB | 04:37 |
| -Bridgestorm- 🏠 زلزله! Zəlzələ! Earthquake! 5.6 M tremor, registered by GFZ,alomax, with 46 reports, 11 early, occurred 7 minutes ago (02:39:28 UTC), during twilight, Haftkel, Iran, Islamic Republic of (31.61, 49.39) ± 121 km likely felt 440 km away (in ویس, اهواز…) by 1.6 million people (www.seismicportal.eu) | 04:47 | |
| Brainstorm | New from COVID tweets: Eric Topol (@EricTopol): An extraordinary 90 second video of the hotspots and spread throughout the American pandemic, by @BioTurboNick youtube.com/watch?v=bVqMQS… → https://is.gd/Kur2Tu | 04:58 |
| Brainstorm | New from The Indian Express: World: Two Koreas reopen hotlines as North urges South to mend ties → https://is.gd/vTMZdH | 05:08 |
| Brainstorm | New from Reddit (test): COVID19: Nonpharmaceutical Interventions Remain Essential to Reducing Coronavirus Disease 2019 Burden Even in a Well-Vaccinated Society: A Modeling Study → https://is.gd/Fzi8BX | 06:01 |
| Brainstorm | Updates for Pakistan: +1490 cases (now 1.3 million), +27 deaths (now 27893), +52415 tests (now 19.6 million) since 22 hours ago | 06:10 |
| Brainstorm | New from r/WorldNews: worldnews: North Korea reopens hotline with South in bid to mend ties - BBC News → https://is.gd/0JKDOn | 06:22 |
| sdfgsdfg | north korea in ##covid-19 :S | 06:46 |
| Brainstorm | Updates for India: +20799 cases (now 33.8 million), +2257410 tests (now 574.3 million) since 23 hours ago | 06:59 |
| jbwncster | There is no covid in North Korea lol | 07:13 |
| Brainstorm | Updates for Terengganu, Malaysia: +827 cases (now 57989) since a day ago — Lombardy, Italy: +328 cases (now 884814), +4 deaths (now 34054) since a day ago — Hebei, China: +1 cases (now 1318) since 16 days ago | 07:37 |
| Brainstorm | New from COVID tweets: Eric Topol (@EricTopol): The >30-fold impact of vaccination for reducing hospitalization for age 60+ vs <18 years pic.twitter.com/Gtlq9zvS7V → https://is.gd/kLb0Hz | 07:45 |
| Bridgestorm | ❗ 地震预警 / EARTHQUAKE WARNING for Taiwan (just felt near Hsinchu?) — Follow for updates (www.kmoni.bosai.go.jp) | 08:08 |
| -Bridgestorm- 🏠 地震! Earthquake! 5.9 M tremor, registered by yurekuru, occurred 2 minutes ago (06:07:30 UTC), during daytime, Hsinchu, Taiwan (24.9, 120.8), ↓10 km likely felt 250 km away (in 新竹市, 桃園市, 新北市, 東區, 竹北市…) by 16.1 million people → https://twitter.com/yurekuru/status/1444907207867256839 — Webcams: https://www.windy.com/webcams/1605081055 https://www.windy.com/webcams/1601022329 | 08:09 | |
| -Bridgestorm- https://www.windy.com/webcams/1628710704 (Twitter) | 08:09 | |
| Brainstorm | New from Reddit (test): CoronaVirus_2019_nCoV: Man suffers heart attack, dies after failing to find an ICU bed in 5 different states → https://is.gd/inRSgU | 08:17 |
| Brainstorm | New from r/Coronavirus: Daily Discussion Thread | October 04, 2021: Please refer to our Wiki for more information on COVID-19 and our sub. You can find answers to frequently asked questions in our FAQ , where there is valuable information such as our: → https://is.gd/ZMyVBS | 09:10 |
| Brainstorm | Updates for Czechia: +317 cases (now 1.7 million), +32470 tests (now 38.4 million) since 23 hours ago — Taiwan: +5 cases (now 16255), +1 deaths (now 844), +93656 tests (now 6.5 million) since 23 hours ago | 09:35 |
| Brainstorm | Updates for Hungary: +1492 cases (now 824876), +31 deaths (now 30230), +32255 tests (now 7.0 million) since 3 days ago — Macau: +1 cases (now 72), +10 tests (now 4906) since 5 days ago | 10:00 |
| Brainstorm | Updates for Barbados: +218 cases (now 9010), +2176 tests (now 324652) since a day ago | 10:37 |
| Brainstorm | New from r/WorldNews: worldnews: 'Return to zero incredibly difficult': New Zealand abandons COVID-19 elimination strategy → https://is.gd/h3c22t | 11:07 |
| Brainstorm | Updates for Russia: +25781 cases (now 7.6 million), +883 deaths (now 210801), +500000 tests (now 193.7 million) since a day ago — Austria: +1404 cases (now 750229), +8 deaths (now 11034), +287120 tests (now 88.4 million) since 23 hours ago — Poland: +683 cases (now 2.9 million), +51758 tests (now 21.0 million) since 23 hours ago | 11:39 |
| Brainstorm | New from Reddit (test): CoronavirusUK: New Zealand drops COVID-19 elimination strategy under pressure from Delta → https://is.gd/ZX7QSO | 11:49 |
| Brainstorm | Updates for Indonesia: +922 cases (now 4.2 million), +88 deaths (now 142261), +713952 vaccines (now 93.8 million), +232517 tests (now 40.1 million) since 23 hours ago — Japan: +550 cases (now 1.7 million), +24 deaths (now 17756), +1132688 vaccines (now 90.3 million) since 22 hours ago [... want %more?] | 12:29 |
| Brainstorm | New from The Indian Express: World: New Zealand admits it can no longer get rid of coronavirus → https://is.gd/BzybXd | 12:33 |
| Brainstorm | New from r/Science: science: Depression rates tripled and symptoms intensified during first year of COVID-19. Researchers found 32.8% of US adults experienced elevated depressive symptoms in 2021, compared to 27.8% of adults in the early months of the pandemic in 2020, and 8.5% before the pandemic. → https://is.gd/fM49hJ | 12:44 |
| Brainstorm | Updates for Laos: +307 cases (now 25524), +4951 tests (now 518530) since 22 hours ago — UAE: +189 cases (now 736897), +1 deaths (now 2103), +261502 tests (now 85.1 million) since 23 hours ago — Senegal: +2 cases (now 73802), +1411 tests (now 805895) since 23 hours ago | 13:06 |
| Brainstorm | New from COVID tweets: Anthony J Leonardi, PhD, MS (@fitterhappierAJ): Delta has thrust us into a world of forevercovid (temporarily)apnews.com/article/corona… twitter.com/fitterhappierA… pic.twitter.com/Yp66KaSEbc → https://is.gd/fL5IQG | 13:49 |
| Brainstorm | Updates for Uganda: +63 cases (now 124039), +2 deaths (now 3162), +3878 tests (now 1.7 million) since 12 hours ago | 14:08 |
| lastshell | https://www.nytimes.com/2021/10/04/briefing/covid-caseload-retreat-us-cases.html 2 months cycle Dr. Eric Topol | 14:23 |
| Brainstorm | New from COVID tweets: WesElyMD (@WesElyMD): True: We’ve delivered “#COVID babies” in moms’ ICU beds throughout the #Pandemic. Why there? Because moms are in shock on life support & it’s the only way. Days later they point to their stomach asking…? It’s SO SAD. A few more days later, they ALL SAY, “I wish I’d #VAXXED. 😭 [... want %more?] → https://is.gd/UWOssP | 14:32 |
| Brainstorm | Updates for Switzerland: +2636 cases (now 844209), +3 deaths (now 11108), +103386 tests (now 11.0 million) since 2 days ago — Nepal: +812 cases (now 798004), +10 deaths (now 11174), +5893 tests (now 4.2 million) since a day ago — Bangladesh: +794 cases (now 1.6 million), +18 deaths (now 27591), +24928 tests (now 9.8 million) since 22 hours ago | 14:33 |
| Brainstorm | New from WHO Euro: Physical activity promoting policies in the era of COVID-19: is Europe on the right track?: European Union (EU) countries have been making gains in the development of policy on physical activity promotion since 2015, but during the COVID-19 pandemic progress has slowed down, shows a recent WHO publication. The new report, “2021 [... want %more?] → https://is.gd/UTvONM | 15:27 |
| Brainstorm | New from EMA: News and press releases: Comirnaty and Spikevax: EMA recommendations on extra doses and boosters, , 04/10/2021: EMA’s human medicines committee (CHMP) has concluded that an extra dose of the COVID-19 vaccines Comirnaty (BioNTech/Pfizer) and Spikevax (Moderna) may... → https://is.gd/EdYLNI | 16:00 |
| Brainstorm | Updates for Qatar: +77 cases (now 236990), +5394 tests (now 2.7 million) since a day ago — Saudi Arabia: +53 cases (now 547315), +3 deaths (now 8727), +47386 tests (now 29.1 million) since a day ago — Zambia: +9 cases (now 209172), +3073 tests (now 2.5 million) since a day ago — Gibraltar: +6 cases (now 5579), +396 tests (now 363987) since 14 hours ago | 16:00 |
| Brainstorm | New from COVID tweets: Eric Topol (@EricTopol): The importance of age can't be emphasized enoughnymag.com/intelligencer/… by @dwallacewells @NYMag "To put it more bluntly: in assessing an individual’s risk of dying from COVID, age appears still as important — and maybe even more important — than vaccination status." → https://is.gd/mNt0tQ | 16:22 |
| Brainstorm | New from COVID tweets: Eric Topol (@EricTopol): A universal sarbecovirus vaccine. We should be all over this, but we're not. It needs to get top priority and for there to be a global collaborative effort. wsj.com/articles/to-pr… by @betswrites pic.twitter.com/NtflyRwdZM → https://is.gd/yVQDIC | 16:32 |
| Brainstorm | Updates for San Marino: +4 cases (now 5444), +771 tests (now 79868) since 3 days ago | 16:38 |
| Brainstorm | New from COVID tweets: Marc Veldhoen (@Marc_Veld): EMA’s human medicines committee (CHMP) has concluded that an extra dose of the COVID-19 vaccines Comirnaty (BioNTech/Pfizer) and Spikevax (Moderna) may be given to people with severely weakened immune systems, at least 28 days after their second dose.ema.europa.eu/en/news/comirn… → https://is.gd/7QTahp | 16:43 |
| de-facto | .title https://www.wsj.com/articles/to-prevent-the-next-pandemic-scientists-seek-one-vaccine-for-many-coronaviruses-11633339802?st=rympt75tje1xzoh | 16:45 |
| Brainstorm | de-facto: From www.wsj.com: To Prevent the Next Pandemic, Scientists Seek One Vaccine for Many Coronaviruses - WSJ | 16:45 |
| de-facto | .title https://www.pnas.org/content/118/38/e2106433118 | 16:45 |
| Brainstorm | de-facto: From www.pnas.org: Efficacy and breadth of adjuvanted SARS-CoV-2 receptor-binding domain nanoparticle vaccine in macaques | PNAS | 16:45 |
| de-facto | .title https://www.science.org/doi/full/10.1126/science.abi4506 | 16:45 |
| Brainstorm | de-facto: From www.science.org: Chimeric spike mRNA vaccines protect against Sarbecovirus challenge in mice | 16:46 |
| de-facto | .title https://www.sciencedirect.com/science/article/pii/S009286742101062X | 16:46 |
| Brainstorm | de-facto: From www.sciencedirect.com: Elicitation of broadly protective sarbecovirus immunity by receptor-binding domain nanoparticle vaccines - ScienceDirect | 16:46 |
| lastshell | is possible to have one magic vax against all coronavirus ? | 16:46 |
| de-facto | .title https://www.science.org/doi/10.1126/science.abj3321 | 16:46 |
| Brainstorm | de-facto: From www.science.org: Broad betacoronavirus neutralization by a stem helix–specific human antibody | 16:46 |
| Brainstorm | New from Politico: Clinical trials: EU regulator backs Pfizer vaccine booster for all adults after 6 months → https://is.gd/QFYD3O | 16:55 |
| Brainstorm | Updates for India: +11589 cases (now 33.8 million), +186 deaths (now 449214) since 20 hours ago | 17:02 |
| de-facto | .title https://www.timesofisrael.com/life-saver-boosters-cut-elderlys-risk-of-covid-death-to-50th-of-unvaxxed-rate/ | 17:05 |
| Brainstorm | de-facto: From www.timesofisrael.com: Israel data: Boosters cut elderlyâs risk of COVID death to 50th of unvaxxed rate | The Times of Israel | 17:05 |
| Brainstorm | New from StatNews: What we know — and don’t know — about Merck’s new Covid-19 pill: STAT looks at the unanswered questions about Merck's new Covid-19 drug, molnupiravir, and about other Covid-fighting pills in development. → https://is.gd/cEDxrO | 17:05 |
| Brainstorm | New from NPR: Get a fan and get vaccinated, the CDC says in its safety tips for the holidays: "When you have something spread by aerosol, you absolutely want more ventilation," Dr. Anthony Fauci, chief medical adviser to President Biden, said in an interview with CBS. → https://is.gd/UgLbP5 | 17:16 |
| Brainstorm | New from NPR: New Zealand acknowledges it can no longer completely get rid of the coronavirus: Since early in the pandemic, New Zealand had pursued a zero-tolerance approach through strict lockdowns and aggressive contact tracing. Until recently, the strategy had worked remarkably well. → https://is.gd/QjiQLB | 17:38 |
| Brainstorm | Updates for Netherlands: +1644 cases (now 2.0 million), +3 deaths (now 18600) since 15 hours ago — Germany: +5110 cases (now 4.3 million), +13 deaths (now 94302) since 21 hours ago — France: +757 cases (now 7.1 million) since 20 hours ago — Canada: +1353 cases (now 1.6 million), +8 deaths (now 28004) since 22 hours ago | 17:40 |
| Brainstorm | New from WebMD: Colon Cancer Diagnoses Fell 40% in Pandemic, and That's Not Good News: From a study in Spain, those who were diagnosed in the pandemic year were older than in the pre-pandemic year, had more frequent symptoms, greater complications and were seen at a more advanced disease stage. → https://is.gd/I4zMGF | 18:01 |
| Brainstorm | Updates for Greece: +2125 cases (now 663433), +36 deaths (now 14956), +74425 tests (now 20.8 million) since a day ago — Chile: +654 cases (now 1.7 million), +6 deaths (now 37500), +52355 tests (now 22.1 million) since a day ago | 18:05 |
| TurboTech | Hello. Seems Facebook is experiencing a major outage | 18:14 |
| lastshell | people still using FB ? | 18:18 |
| TurboTech | I use it for my business. | 18:19 |
| TurboTech | Older people use facebook. | 18:19 |
| TurboTech | It is easy for them and I sell my photos to the parents so it is a good deal | 18:19 |
| lastshell | I stopped using all social media platforms, because imho are just cancer | 18:22 |
| lastshell | I guess if i have a bussines maybe I will use fb | 18:22 |
| Brainstorm | Updates for Italy: +1612 cases (now 4.7 million), +37 deaths (now 131068), +122214 tests (now 93.5 million) since a day ago | 18:30 |
| TurboTech | It also allows me to keep tabs on people who choose to use a different service. Like people who use other photoggraphers to take their kids senior photos. | 18:30 |
| LjL | https://www.reddit.com/r/worldnews/comments/q183m2/israel_bans_anyone_without_booster_from_entering/ "not appropriate subreddit" wtf? | 19:13 |
| LjL | i mean yes it's daily mail, but there's even an automoderator post automatically saying that is okay per se | 19:13 |
| xrogaan | .title somebody shared this with me: https://ijvtpr.com/index.php/IJVTPR/article/view/23 | 19:22 |
| Brainstorm | xrogaan: From ijvtpr.com: Worse Than the Disease? Reviewing Some Possible Unintended Consequences of the mRNA Vaccines Against COVID-19 | International Journal of Vaccine Theory, Practice, and Research | 19:22 |
| Brainstorm | xrogaan: From ijvtpr.com: Worse Than the Disease? Reviewing Some Possible Unintended Consequences of the mRNA Vaccines Against COVID-19 | International Journal of Vaccine Theory, Practice, and Research | 19:22 |
| xrogaan | oops | 19:22 |
| xrogaan | is it worth paying attention to? Paper of 52 pages distributed on open access. | 19:22 |
| LjL | xrogaan, if i start googling the interesting journal name of "ijvtpr", that particular paper comes up as the first suggestion before i'm even done typing the acronym | 19:24 |
| LjL | that suggests to me the journal may be a little phony | 19:24 |
| Brainstorm | New from The Indian Express: World: Indonesia to reopen Bali to international flights on October 14 → https://is.gd/r2KBRb | 19:25 |
| LjL | https://www.quora.com/Is-The-International-Journal-of-Vaccine-Theory-Practice-and-Research-a-serious-science-based-publication-or-a-mouthpiece-for-anti-vaxxers | 19:26 |
| LjL | i wouldn't waste my time any further | 19:27 |
| xrogaan | I was kind of suspicious at the lack of citations. | 19:36 |
| xrogaan | Usually, there is a DOI linked with published papers for ease of citation and research. | 19:36 |
| nixonix | .title https://twitter.com/EricTopol/status/1445047888409608192 | 19:41 |
| Brainstorm | nixonix, the URL could not be loaded | 19:41 |
| nixonix | .title https://twitter.com/EricTopol/status/1445047888409608192 | 19:42 |
| Brainstorm | nixonix: From twitter.com: Eric Topol (@EricTopol): "New report on very rare acute myocarditis after mRNA vaccination in age 18+ 5.8 cases/million after 2nd dose, 0.8/million 1st dose, all cases fully resolved with conservative [...] | 19:42 |
| nixonix | "Symptoms resolved with conservative management in all cases; no patients required intensive care unit admission or readmission after discharge | 19:43 |
| nixonix | i was thinking, if its immune cell mediated, like killer t-cells, it may happen because unlike with natural infection which starts slowly whith increasing numbers of virions, the especially mrna vaccine induces S protein in cell surfaces fast | 19:46 |
| Brainstorm | New from r/Science: science: Clinical trial concluded that convalescent plasma is “futile” as a COVID-19 treatment for most critically ill patients. The trial concluded for futility when enough data was collected to say with greater than 99% certainty that convalescent plasma did not help critically ill COVID-19 patients. → https://is.gd/69dYol | 19:47 |
| nixonix | so sudden increase in immune cell activity towards those cells wont be regulated by Tregs, which would take around 6 days time | 19:47 |
| nixonix | and with viral vector vaccines myocarditis is rare, because its slower, Tregs have more time to interrupt | 19:48 |
| nixonix | and in "natural infection", where myocarditis is more common than with mrna vaxes: "CD4+CD25+CD39+ mTreg cells were decreased in mild and severe COVID-19 patients" | 19:53 |
| nixonix | but while it could be about some other immune cells infiltrating, rather than killer t-cells, it would need to happen fast after the 2nd vaccine dose, because its usually just few days after the 2nd dose, and later Tregs would suppress the activity anyway | 19:55 |
| nixonix | so that would happen because when the dose interval is just 3-4 weeks, theres still enough immune cell activity left from the 1st dose, for that to happen fast (unlike like eg killer t-cells, which usually peak around 8-14 days after viral infection) | 19:56 |
| xrogaan | and what are you going to do with this killer information? | 19:57 |
| nixonix | if that would be the case, then with longer dose intervals there should be less myocarditis from mrna vaccines, and it would be closer to 1st dose induced rate (or background noise) | 19:57 |
| Brainstorm | New from WebMD: Fauci: ‘Too Soon to Tell’ on Major Holiday Gatherings: It’s too early to determine whether Americans should avoid large family gatherings for Christmas and other holidays due to COVID-19, Anthony Fauci, MD, director of the National Institute of Allergy and Infectious Diseases, said Sunday. → https://is.gd/TuuxrB | 19:58 |
| nixonix | so in uk with longer intevals, after the first few weeks, there should be less myocarditis, and the rate close to similar after 1st and 2nd dose. and the same in finland, so i checked it here... | 19:58 |
| nixonix | "Since the first dose of the vaccine, a total of 26 hospital-acquired myocarditis has been reported out of a total of about 3.8 million vaccinated. Of the cases, 22 have been reported in men and 4 in women. Since the second dose of the vaccine, a total of 21 cases requiring hospitalization have been identified out of approximately three million | 20:00 |
| nixonix | vaccinated. Of the cases, 13 have been reported in men and 8 in women | 20:00 |
| nixonix | and woah, seems to agree with my (yet another) hypothesis | 20:00 |
| nixonix | xrogaan do i know you? | 20:02 |
| xrogaan | dunno, I've been around for over a year. | 20:04 |
| nixonix | okay, what kind of answere are you expecting? | 20:05 |
| nixonix | -e | 20:05 |
| xrogaan | what's the point of all this? | 20:06 |
| * xrogaan waves hands at wall of text | 20:06 | |
| nixonix | so you are telling me i shouldnt write about things happening during this epidemic? why? | 20:07 |
| xrogaan | Seems like specific information. Which people in the field would care about, and subject to further research as it tells nothing by itself. | 20:08 |
| nixonix | so just because you dont care? | 20:08 |
| xrogaan | Why do you answer with questions? I simply asked what you are going to do with that knowledge. | 20:10 |
| nixonix | its not knowledge, just another idea of possible mechanism | 20:11 |
| xrogaan | Is it important enough to change policies? Because it doesn't seem like it would. | 20:11 |
| nixonix | sure it would, if that really was the mechanism. is it, hard to say | 20:11 |
| nixonix | but its consistent with finnish data, happens as often after 1st and 2nd, and its pretty rare here | 20:12 |
| nixonix | so are you going to keep telling me what i shouldnt write here? | 20:14 |
| xrogaan | It's so specific, very few people would be able to follow or care at all. | 20:15 |
| nixonix | if you cant, you can just skip it. lots of people on this channel can. like turbo who seems to be around, and has good understanding of immunology | 20:16 |
| xrogaan | I sure can't use that to make fun of my relatives relaxing their behaviors. | 20:16 |
| LjL | okay, so | 20:16 |
| LjL | xrogaan, this channel isn't just about policy, the science is definitely welcome | 20:17 |
| LjL | nixonix, i've got to say sometimes i feel like your walls of text *may* stifle other discussion. i don't know how else to put it: i think xrogaan's response here wasn't appropriate or "the right response", but i don't know what the right response is, while at the same time feeling *some* kind of feedback is warranted | 20:17 |
| nixonix | so less science talk` | 20:18 |
| nixonix | `? | 20:18 |
| LjL | it's not talk when you're the only one talking | 20:19 |
| nixonix | okay | 20:19 |
| LjL | i think at some point if you start getting into some detail and nobody responds, then i'm not really sure you're doing TurboTech or anyone else who *could* follow at least *some* of it any favor by going on and on and on until there's too much stuff to realistically catch up with | 20:19 |
| LjL | most people can't or won't spend all day reading this channel, and i do believe there is some kind of optimum that is in between "no one ever saying anything" and "one person always speaking" | 20:20 |
| LjL | you also seemingly get upset sometimes when people don't respond to your posts, but i'm not sure you realize they can be highly overwhelming | 20:21 |
| LjL | sure, i can just... not response, because i'm overwhelmed, so that's what i do. maybe many others are doing the same. is that working out very well for you, or for the channel in general? i'm not sure. | 20:21 |
| LjL | i have made some people here leave by my own ragey/primadonna attitude. but maybe that's something a few people who stick around here have in common... | 20:24 |
| xrogaan | heh, I acknowledge that I gave a snide response. However I feel that it was relevant: « what are we to do with the knowledge » or « why should I care ». These are not cutting remarks, they're there to get to the point. Somebody obviously read the paper and as an opinion about it. | 20:25 |
| LjL | whatever, now there'll be largely silence, and if nixonix looks he'll feel vindicated that without him, mostly nobody will be talking. but he'll have been part of the process that led to that. | 20:25 |
| xrogaan | Personally, I really don't need an analysis of the thing. | 20:25 |
| xrogaan | nix left, huh. | 20:26 |
| LjL | yeah | 20:26 |
| LjL | i have an incredible ability to make people leave with a few words | 20:26 |
| LjL | i should use that to fight evil or something | 20:26 |
| Arsanerit | call Assad? | 20:27 |
| LjL | i'm not really sure who the evil ones are | 20:28 |
| TurboTech | Sorry guys, I was out of the room. | 20:28 |
| TurboTech | I had to go to the store and get stuff. | 20:29 |
| xrogaan | Feels like it was an exercise of self-importance, and not one about sharing knowledge. | 20:29 |
| LjL | i think he's stressed about covid in his own way, the annoying thing is a lot of these ways end up making people leave, one way or another | 20:29 |
| TurboTech | Seemed like I missed a few things. | 20:29 |
| Brainstorm | Updates for United Kingdom: +34299 cases (now 8.0 million), +33 deaths (now 137371) since 18 hours ago — Spain: +4271 cases (now 5.0 million), +64 deaths (now 86527) since 3 days ago | 20:40 |
| ublx | xrogaan: he's Finnish. this is just what they're like. kinda | 20:47 |
| ublx | i mean, more akin to aspergers than arrogance, but neither, really | 20:49 |
| Brainstorm | New from WebMD: Vaccine Holdouts Embrace COVID Antibody Treatment, Mystifying Doctors: Doctors and public health experts are surprised that so many of those embracing monoclonal antibody treatment are unvaccinated Americans who have refused the shot for reasons that could very well apply to the newly developed and experimental monoclonal antibody therapy. → https://is.gd/TB1G1C | 20:52 |
| lastshell | honestly for me I have to skip the news a couple of days | 21:07 |
| lastshell | doing this daily builds a toil | 21:07 |
| LjL | yeah | 21:10 |
| Brainstorm | New from COVID tweets: Eric Topol (@EricTopol): When the problem in the US is the N getting booster shots markedly exceeds the newly vaccinated, and the latter are very low and desperately need to increase in order to achieve containmentTotal/New/Boost (1000s)Saturday 933/273/379Sunday 1240/363/545Monday 985/269/424 → https://is.gd/CKcDDz | 21:35 |
| Brainstorm | Updates for France: +1138 cases (now 7.1 million) since 9 hours ago — Germany: +2518 cases (now 4.3 million) since 23 hours ago | 21:36 |
| Brainstorm | New from WebMD: Pfizer COVID Vaccine Antibodies May Disappear in 7 Months, Study Says: Antibody levels may wane after 7 months for people who got the Pfizer-BioNTech vaccine, according to a new study published on the bioRxiv preprint server. → https://is.gd/APqgaO | 21:57 |
| pwr22 | Good news in the myocarditis thing Eric Topol tweeted | 22:36 |
| Brainstorm | Updates for Kuwait: +52 cases (now 411855), +34825 tests (now 4.4 million) since a day ago | 22:38 |
| pwr22 | UK deaths and hospitalisations seem to be down as well as cases now which is very good news | 22:58 |
| Brainstorm | New from StatNews: Pharma: STAT+: The Merck Covid-19 pill may be a game changer, but questions are already being raised about cost → https://is.gd/ZSxoY7 | 23:02 |
| Brainstorm | Updates for India: +16303 cases (now 33.9 million), +254 deaths (now 449283) since 16 hours ago | 23:03 |
| Brainstorm | New from COVID tweets: Prof. Shane Crotty (@profshanecrotty): I had the opportunity to speak Friday at this excellent conference on COVID-19 hosted by the Pasteur Institute (Institut Pasteur). Full presentations are now available online. covid19.conferences-pasteur.org/replay-confere… → https://is.gd/jOt4kZ | 23:13 |
| LjL | <Brainstorm> New from r/WorldNews: worldnews: China PCR test orders soared before first reported COVID case → https://is.gd/pBrOIu | 23:38 |
| Brainstorm | New from COVID tweets: Eric Topol (@EricTopol): How often is Covid testing needed to help reduce Delta variant transmission?Not once per week. Not twice per week.At least every other day.With rapid turnaround time.medrxiv.org/content/10.110… → https://is.gd/xo4EZQ | 23:56 |
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