libera/##covid-19/ Friday, 2021-10-29

BrainstormUpdates for Barbados: +358 cases (now 16782), +2 deaths (now 151), +4353 tests (now 382688) since 22 hours ago — Bahrain: +33 cases (now 276718), +16368 tests (now 6.9 million) since 23 hours ago00:05
BrainstormNew from r/WorldNews: worldnews: Brazil's greenhouse gas emissions rose by 9.5 percent last year, mostly because of deforestation, a report said Thursday, making it one of the only major economies not to cut pollution as the pandemic hit → https://old.reddit.com/r/worldnews/comments/qhxlia/brazils_greenhouse_gas_emissions_rose_by_95/00:11
BrainstormNew from The Lancet (Online): [Correspondence] Characteristics and risk of COVID-19-related death in fully vaccinated people in Scotland: Vaccines are highly effective in preventing COVID-19 hospitalisations and deaths.1,2 COVID-19-related deaths in fully vaccinated individuals have, [... want %more?] → https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(21)02316-3/fulltext00:33
de-facto.title https://covid19scenariomodelinghub.org/viz.html00:49
Brainstormde-facto: From covid19scenariomodelinghub.org: Home - COVID 19 scenario model hub00:49
BrainstormUpdates for Bulgaria: +5178 cases (now 592943), +124 deaths (now 23718), +49288 tests (now 5.5 million) since a day ago — Argentina: +1589 cases (now 5.3 million), +27 deaths (now 115916), +51065 tests (now 25.0 million) since 23 hours ago01:08
BrainstormNew from COVID tweets: Eric Topol (@EricTopol): Breakthrough Covid deaths from fully vaccinated status are very rare, 0.007% for Scotland country-wide; most of the 236 deaths occurred in people older than 75 years who had multiple comorbiditiesthelancet.com/journals/lance… @TheLancet pic.twitter.com/SBBdJjhrb0 → https://twitter.com/EricTopol/status/145386104731659879601:14
BrainstormUpdates for Germany: +8079 cases (now 4.6 million) since 18 hours ago01:33
BrainstormNew from COVID tweets: Michael Lin, PhD-MD 🧬 (@michaelzlin): Empirical confirmation that vaccines only block at getting sick, and not at transmitting onwards.Predicted in the thread above.twitter.com/jeremyfaust/st… → https://twitter.com/michaelzlin/status/145386743339190272201:35
BrainstormNew from COVID tweets: Eric Topol (@EricTopol): "Patients with multiple myeloma frequently present with substantial immune impairment and an increased risk for [Covid] infections and infection-related mortality."thelancet.com/journals/lanha… @TheLancetHaem A review by 36 experts. Of relevance to the recent passing [... want %more?] → https://twitter.com/EricTopol/status/145386873834054861201:45
BrainstormUpdates for Uruguay: +260 cases (now 393139), +21513 tests (now 3.8 million) since a day ago — Paraguay: +50 cases (now 460944), +5 deaths (now 16243), +1813 tests (now 1.9 million) since a day ago — Mali: +22 cases (now 15947), +1 deaths (now 562), +2202 tests (now 451027) since 5 hours ago02:10
BrainstormNew from Reddit (test): China_Flu: Effect of early treatment with fluvoxamine on risk of emergency care and hospitalisation among patients with COVID-19: the TOGETHER randomised, platform clinical trial → https://old.reddit.com/r/China_Flu/comments/qi09sx/effect_of_early_treatment_with_fluvoxamine_on/02:27
sdfgsdfgis anyone here not vaccinated02:28
JuerdI'm vaccinated02:29
sdfgsdfgthat's a relief02:30
JuerdActually, it is :)02:30
sdfgsdfgI think it's time we start banning the unvaccinated from here too02:30
`St0ner+v for vaccinated02:31
Juerdsdfgsdfg: It's not a computer virus :)02:32
sdfgsdfgyou need to actually be verified for this new voice privilege though02:32
BrainstormUpdates for Zimbabwe: +72 cases (now 132880), +3966 tests (now 1.5 million) since a day ago02:35
BrainstormNew from Virology.ws: Wuhan spiny eel influenza virus: Influenza B viruses, unlike influenza A viruses, do not cause pandemics. There are many non-human animal reservoirs of influenza A viruses which provide gene segments that go towards making reassortant viruses that can infect humans. Influenza B [... want %more?] → https://www.virology.ws/2021/10/28/wuhan-spiny-eel-influenza-virus/02:58
BrainstormUpdates for Netherlands: +7706 cases (now 2.1 million) since 23 hours ago03:37
BrainstormNew from r/WorldNews: worldnews: India tests nuclear-capable missile amid tensions with China → https://old.reddit.com/r/worldnews/comments/qi1uvl/india_tests_nuclearcapable_missile_amid_tensions/04:01
BrainstormNew from r/WorldNews: worldnews: UK ends direct funding of Palestinian teachers amid covid cost-cutting → https://old.reddit.com/r/worldnews/comments/qi21ip/uk_ends_direct_funding_of_palestinian_teachers/04:11
BrainstormUpdates for South Korea: +2124 cases (now 360536), +9 deaths (now 2817), +52599 tests (now 15.7 million) since a day ago — New Zealand: +128 cases (now 6124), +32235 tests (now 4.0 million) since 23 hours ago — United Kingdom: +39224 cases (now 9.0 million) since 11 hours ago04:39
BrainstormNew from COVID tweets: Eric Topol (@EricTopol): Not once in 2021 for the pandemic has @WhiteHouse @POTUS @WHCOVIDResponse @HHSGov @SecBecerra announced intent to address/fix the serious data deficiency issues. We've had 1 incomplete (30% of population) Sept 4th shot. 100% can be mandated. But obviously this is not a priority. → https://twitter.com/EricTopol/status/145391263545645056004:42
BrainstormUpdates for Belgium: +9195 cases (now 1.4 million), +30 deaths (now 25976) since 23 hours ago — Peru: +998 cases (now 2.2 million), +30 deaths (now 200179), +44385 tests (now 19.0 million) since 22 hours ago — Canada: +2640 cases (now 1.7 million) since 23 hours ago05:29
BrainstormNew from Reddit (test): CoronaVirus_2019_nCoV: gdd → https://old.reddit.com/r/CoronaVirus_2019_nCoV/comments/qi3w6p/gdd/05:45
Guest5526hi05:58
BrainstormNew from r/WorldNews: worldnews: Fully vaccinated Ontario man dies after COVID-19 sweeps through his hockey league → https://old.reddit.com/r/worldnews/comments/qi3z1q/fully_vaccinated_ontario_man_dies_after_covid19/06:05
BrainstormUpdates for Panama: +140 cases (now 472197), +7051 tests (now 4.1 million) since a day ago06:06
BrainstormNew from r/Science: science: New research provides evidence that internet memes can help people cope with the stress of a global pandemic by boosting positive emotions. The findings indicate that viewing memes can have psychologically beneficial effects. → https://old.reddit.com/r/science/comments/qi4eoa/new_research_provides_evidence_that_internet/06:26
BrainstormUpdates for India: +14348 cases (now 34.2 million) since 23 hours ago06:31
BrainstormNew from r/Science: science: Cheap antidepressant commonly used to treat obsessive-compulsive disorder significantly decreased the risk of Covid-19 patients becoming hospitalized in a large trial. A 10-day course of the antidepressant fluvoxamine cut hospitalizations by two-thirds [... want %more?] → https://old.reddit.com/r/science/comments/qi4tq5/cheap_antidepressant_commonly_used_to_treat/06:47
BrainstormUpdates for Negeri Sembilan, Malaysia: +249 cases (now 102319) since a day ago — Cayman Islands, United Kingdom: +217 cases (now 1496) since 2 days ago — Unknown, Netherlands: +57 cases (now 7040) since a day ago — Lombardy, Italy: +570 cases (now 893025), +3 deaths (now 34148) since a day ago07:40
BrainstormUpdates for Kyrgyzstan: +116 cases (now 181105), +2 deaths (now 2666), +3250 tests (now 1.8 million) since 23 hours ago — United Kingdom: +39225 cases (now 9.0 million) since 14 hours ago08:29
BrainstormNew from r/WorldNews: worldnews: Delta mutation is no reason to panic — but Covid vaccination remains crucial, scientists say → https://old.reddit.com/r/worldnews/comments/qi6inn/delta_mutation_is_no_reason_to_panic_but_covid/08:52
BrainstormNew from r/Coronavirus: Daily Discussion Thread | October 29, 2021: Please refer to our Wiki for more information on COVID-19 and our sub. You can find answers to frequently asked questions in our FAQ , where there is valuable information such as our: → https://old.reddit.com/r/Coronavirus/comments/qi6xcg/daily_discussion_thread_october_29_2021/09:03
BrainstormUpdates for Georgia: +3965 cases (now 711255), +43 deaths (now 9961), +48513 tests (now 10.1 million) since 23 hours ago09:32
BrainstormNew from WHO Euro: WHO/Europe: Keep schools open this winter – but with precautions in place: WHO/Europe calls for schools to stay open – with appropriate prevention and response measures in place – as the WHO European Region reports 4 [... want %more?] → http://feedproxy.google.com/~r/who/euro/rss/en/~3/VbC_LYF1EOs/whoeurope-keep-schools-open-this-winter-but-with-precautions-in-place09:34
BrainstormNew from Reddit (test): CoronaVirus_2019_nCoV: Moscow begins new restrictions as Russia's COVID-19 deaths hit a record high : NPR → https://old.reddit.com/r/CoronaVirus_2019_nCoV/comments/qi7r4a/moscow_begins_new_restrictions_as_russias_covid19/10:05
BrainstormUpdates for Hungary: +4041 cases (now 863419), +37 deaths (now 30729), +23069 tests (now 7.4 million) since a day ago — Lithuania: +3519 cases (now 403051), +34 deaths (now 5800), +25859 tests (now 5.6 million) since a day ago — Papua New Guinea: +285 cases (now 29108), +22 deaths (now 367), +5243 tests (now 212450) since 22 hours ago10:09
BrainstormNew from Reddit (test): CoronaVirus_2019_nCoV: If You Have A Mood Disorder, You May Now Be Eligible For A COVID Booster: studies have found that people with mood disorders such as depression have a similar risk of hospitalization and death from COVID when compared to [... want %more?] → https://old.reddit.com/r/CoronaVirus_2019_nCoV/comments/qi82c3/if_you_have_a_mood_disorder_you_may_now_be/10:26
BrainstormNew from Reddit (test): CoronaVirus_2019_nCoV: Third dose of Covid-19 vaccine benefits dialysis patients: In some patients, the immune system responds poorly to the second vaccination dose. This changes with the third shot. → https://old.reddit.com/r/CoronaVirus_2019_nCoV/comments/qi86wk/third_dose_of_covid19_vaccine_benefits_dialysis/10:37
BrainstormNew from Reddit (test): CoronaVirus_2019_nCoV: DHR Health involved in new COVID treatment study: polyclonal antibody treatment will be used to treat non-hospitalized patients who are older than 18-years-old. SAB-185 → https://old.reddit.com/r/CoronaVirus_2019_nCoV/comments/qi8ctg/dhr_health_involved_in_new_covid_treatment_study/10:47
BrainstormNew from EMA: What's new: Document: Rabies vaccine : List of nationally authorised medicinal products - PSUSA/00009277/202103 → https://www.ema.europa.eu/documents/psusa/rabies-vaccine-list-nationally-authorised-medicinal-products-psusa/00009277/202103_en.pdf11:08
BrainstormUpdates for Slovakia: +4587 cases (now 474595), +23 deaths (now 13000), +17338 tests (now 3.9 million) since 23 hours ago — Armenia: +2096 cases (now 304546), +43 deaths (now 6232), +18141 tests (now 2.1 million) since a day ago11:11
BrainstormUpdates for Poland: +9403 cases (now 3.0 million), +102 deaths (now 76875) since a day ago — Germany: +23228 cases (now 4.6 million) since 20 hours ago — Estonia: +1679 cases (now 190201), +11 deaths (now 1502), +7626 tests (now 2.1 million) since a day ago11:36
BrainstormNew from The Indian Express (Health): Life-style: Ahead of Diwali, artisans of Bengal’s pottery village battle Covid curbs, rising fuel prices → https://indianexpress.com/article/lifestyle/life-style/ahead-of-diwali-artisans-of-bengals-pottery-village-battle-covid-curbs-rising-fuel-prices-7596815/11:40
BrainstormUpdates for Austria: +5861 cases (now 819195), +17 deaths (now 11333), +312927 tests (now 96.6 million) since a day ago — Finland: +572 cases (now 157531), +8 deaths (now 1158), +11212 tests (now 7.5 million) since 23 hours ago — Brunei: +132 cases (now 12955), +3 deaths (now 86), +3935 tests (now 497082) since 23 hours ago12:01
BrainstormNew from EMA: What's new: General: COVID-19: latest updates → https://www.ema.europa.eu/en/human-regulatory/overview/public-health-threats/coronavirus-disease-covid-19/covid-19-latest-updates12:23
darsieAustria12:29
BrainstormUpdates for Laos: +447 cases (now 38728), +2 deaths (now 61), +5588 tests (now 627852) since 23 hours ago — Gambia: +2 cases (now 9965), +13656 tests (now 117604) since a day ago12:38
BrainstormNew from COVID tweets: Prof Francois Balloux (@BallouxFrancois): More transmissible SARSCoV2 lineages tend to be more virulent - contrary to what many people think - likely because faster replication of the virus is more damaging to the host's tissues (virus kills cells when they replicate).18/ → https://twitter.com/BallouxFrancois/status/145403838967472537912:55
BrainstormUpdates for Belarus: +1988 cases (now 596191), +16 deaths (now 4596), +40232 tests (now 9.6 million) since 21 hours ago — Indonesia: +683 cases (now 4.2 million), +28 deaths (now 143361), +244392 tests (now 46.3 million) since a day ago — Nepal: +490 cases (now 811897), +6 deaths (now 11388), +7145 tests (now 4.4 million) since 23 hours ago [... want %more?]13:03
BrainstormNew from COVID tweets: Prof Francois Balloux (@BallouxFrancois): Thus, there is a possibility thatSARSCoV2 may evolve towards lower virulence in the future, not to spare its host as is often assumed, but because of a likely tradeoff between immune escape and transmissibility / infectivity.19/ → https://twitter.com/BallouxFrancois/status/145403839165019340813:06
BrainstormNew from Novavax: Novavax Files for Provisional Approval of its COVID-19 Vaccine in Australia: -- Application marks the first protein-based COVID-19 vaccine submitted to regulatory authorities for provisional approval in Australia → https://ir.novavax.com/2021-10-29-Novavax-Files-for-Provisional-Approval-of-its-COVID-19-Vaccine-in-Australia13:16
BrainstormUpdates for Latvia: +2758 cases (now 214460), +25 deaths (now 3198), +10585 vaccines (now 1.1 million), +29633 tests (now 4.9 million) since a day ago — Uganda: +80 cases (now 126000), +1 deaths (now 3210), +279061 vaccines (now 2.9 million), +3847 tests (now 1.8 million) since a day ago13:40
BrainstormUpdates for Romania: +12474 cases (now 1.6 million), +481 deaths (now 46911), +66679 tests (now 14.7 million) since a day ago — Iceland: +79 cases (now 13492), +3087 tests (now 1.1 million) since 21 hours ago — Eq. Guinea: +68 cases (now 13304), +3 deaths (now 166), +3854 tests (now 242340) since 2 days ago — Senegal: +5 cases (now 73909), +1261 tests (now 837154) since a day ago14:05
BrainstormNew from New Scientist: Covid-19 news: Fully vaccinated can still get covid-19 from household: The latest coronavirus news updated every day including coronavirus cases, the latest news, features and interviews from New Scientist and essential information [... want %more?] → https://www.newscientist.com/article/2237475-covid-19-news-fully-vaccinated-can-still-get-covid-19-from-household/14:09
BrainstormNew from ProPublica: America’s Food Safety System Failed to Stop a Salmonella Epidemic. It’s Still Making People Sick.: by Bernice Yeung , Michael Grabell , Irena Hwang and Mollie Simon ] ProPublica is a nonprofit newsroom that investigates abuses of power. Sign up to receive our biggest [... want %more?] → https://www.propublica.org/article/salmonella-chicken-usda-food-safety#115064314:30
BrainstormUpdates for Switzerland: +1722 cases (now 872556) since 23 hours ago — Germany: +23611 cases (now 4.6 million) since 23 hours ago — Zambia: +30 cases (now 209702), +4681 tests (now 2.6 million) since 23 hours ago — United Kingdom: +39241 cases (now 9.0 million) since 20 hours ago14:30
sKep%cases India14:32
BrainstormsKep: India has had 34.2 million confirmed cases (2.5% of all people) and 457221 deaths (1.3% of cases) as of 8 hours ago. 605.9 million tests were done (5.7% positive). 725.6 million were vaccinated (53.3%). +14348 cases since 23 hours ago. See https://www.mygov.in/covid-19 or https://www.covid19india.org/14:32
BrainstormNew from Contagion Live: us: Early Treatment with Fluvoxamine Reduces COVID-19 Hospitalizations → https://www.contagionlive.com/view/early-treatment-with-fluvoxamine-reduces-covid-19-hospitalizations15:03
BrainstormUpdates for UAE: +82 cases (now 739736), +1 deaths (now 2136), +297148 tests (now 92.8 million) since a day ago15:07
BrainstormNew from COVID tweets: Boback Ziaeian 🤦🏻‍♂️ (@boback): Children Drive Britain’s Longest-Running Covid Surge ⁦@nytimes⁩  nytimes.com/interactive/20… → https://twitter.com/boback/status/145407342588703949415:24
BrainstormUpdates for Bangladesh: +305 cases (now 1.6 million), +7 deaths (now 27854), +17811 tests (now 10.3 million) since a day ago15:32
BrainstormNew from StatNews: STAT+: Pharmalittle: Pelosi tries last-ditch drug pricing proposal; Merck sees up to $7B in Covid pill sales in 2022: Merck forecast between $5 billion and $7 billion in sales of its Covid-19 pill through the end of 2022, assuming emergency use authorization is [... want %more?] → https://www.statnews.com/pharmalot/2021/10/29/covid19-vaccine-merck-jnj-medicare-pelosi/15:35
de-facto.title https://www.medrxiv.org/content/10.1101/2021.09.28.21264260v215:40
Brainstormde-facto: From www.medrxiv.org: The impact of SARS-CoV-2 vaccination on Alpha & Delta variant transmission | medRxiv15:40
de-facto"We performed a retrospective observational cohort study of adult contacts of SARS-CoV-2-infected adult index cases using English contact testing data. "15:40
de-facto"54,667/146,243(37.4%) PCR-tested contacts of 108,498 index cases were PCR-positive."15:41
de-facto"Two doses of BNT162b2 or ChAdOx1 vaccines in Alpha index cases were independently associated with reduced PCR-positivity in contacts (aRR, adjusted rate ratio vs. unvaccinated=0.32[95%CI 0.21-0.48] and 0.48[0.30-0.78] respectively)."15:41
de-facto"The Delta variant attenuated vaccine-associated reductions in transmission: two BNT162b2 doses reduced Delta transmission (aRR=0.50[0.39-0.65]), more than ChAdOx1 (aRR=0.76[0.70-0.82]). Variation in Ct values (indicative of viral load) explained 7-23% of vaccine-associated transmission reductions."15:42
de-facto"Transmission reductions declined over time post-second vaccination, for Delta reaching similar levels to unvaccinated individuals by 12 weeks for ChAdOx1 and attenuating substantially for BNT162b2. Protection in contacts also declined in the 3 months post-second vaccination."15:42
de-facto"Vaccination reduces transmission of Delta, but by less than the Alpha variant. The impact of vaccination decreased over time."15:42
BrainstormUpdates for Saudi Arabia: +56 cases (now 548530), +2 deaths (now 8790), +45650 tests (now 30.3 million) since a day ago16:10
de-facto.title https://www.healthsystemtracker.org/brief/covid19-and-other-leading-causes-of-death-in-the-us/16:18
Brainstormde-facto: From www.healthsystemtracker.org: COVID-19 continues to be a leading cause of death in the U.S. in September 2021 - Peterson-KFF Health System Tracker16:19
de-factohttps://pbs.twimg.com/media/FBxuvq4WYAQ_59W?format=jpg&name=large "Over 90,000 COVID-19 deaths since June 2021 likely would have been prevented with vaccinations"16:21
BrainstormNew from ScienceNews: Health & Medicine: What parents need to know about Pfizer’s COVID-19 vaccine for kids ages 5 to 11 → https://www.sciencenews.org/article/covid-coronavirus-vaccine-kids-5-11-pfizer-parents-questions16:29
BrainstormUpdates for Germany: +24477 cases (now 4.6 million) since 23 hours ago — Canada: +2676 cases (now 1.7 million) since 23 hours ago — Switzerland: +2 cases (now 872558) since 2 hours ago16:35
BrainstormNew from COVID tweets: Eric Topol (@EricTopol): The opposite of “flatten the curve” when a low rate of teens are vaccinated, compared with 80+ receiving booster shots twitter.com/paulmainwood/s… → https://twitter.com/EricTopol/status/145409284765786112616:41
de-facto.title https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/1029715/technical-briefing-27.pdf16:47
Brainstormde-facto: From assets.publishing.service.gov.uk: SARS-CoV-2 variants of concern and variants under investigation in England: Technical briefing 27, 29 October 2021 (UKHSA)16:47
de-facto"SARS-CoV-2 variants of concern and variants under investigation in England" Technical briefing 27 29 October 202116:50
de-facto"This report has been published to continue to share the detailed variant surveillance analyses which contribute to the variant risk assessments and designation of new VOCs and VUIs."16:50
de-facto"The Delta sublineage AY.4.2 (VUI-21OCT-01) accounts for a slowly increasing proportion of cases in the UK. It accounts for 8.5% of Delta cases in the most recent complete week of sequencing (4 October 2021 to 10 October 2021). In more recent weeks, sequencing data are incomplete, however AY.4.2 accounts for 10.3% of Delta cases in the week 11 October 2021 to 17 October 2021 and 11.3% in the week 18 October 2021 to 24 October 2021."16:51
de-facto"The growth rate and secondary attack rates have been refreshed with new data and the findings remain the same as last week. Estimated growth rates remain slightly higher for AY.4.2 than for Delta, and the household secondary attack rate is higher for AY.4.2 cases than for other Delta cases."16:52
de-facto"A preliminary rapid vaccine effectiveness analysis does not suggest a significant reduction in vaccine effectiveness for AY.4.2 compared to Delta. However, a further analysis more comprehensive analysis using the standard test negative case control study design is being undertaken."16:52
BrainstormUpdates for India: +6534 cases (now 34.2 million), +81 deaths (now 457246) since 23 hours ago16:59
BrainstormNew from ClinicalTrials.gov: (news): Supporting Audit and Feedback to Encourage Vaccine Uptake → https://clinicaltrials.gov/ct2/show/NCT0509949717:02
de-factoInterestingly the increased hospitalization rates as well as fatality rates for AY.4.2 compared to Delta are balanced in this report 27 in contrast to report 26 (where those were increased)17:04
de-factosee page 5117:04
de-factoi wonder if that somehow is related to that lab in UK giving out loads of false negative PCR tests17:05
de-factolike a founders effect17:06
de-facto"Based on a logistic growth model, the country-wide analysis yields a17:07
de-factologistic growth rate of 19% per week for VUI-21OCT-01. Growth rate is context dependent and17:07
de-factocannot be interpreted as a change in biological transmissibility"17:07
de-factohmm but still they have an increased growth rate for AY.4.2 compared to other Delta variants17:08
de-facto"...secondary attack rates split by type of contact. Secondary attack rate for household contacts of cases with VUI-21OCT-01 was 12.2% (95% CI: 11.8% - 12.7%), higher than that observed for other Delta cases where it was 11.2% (95% CI: 11.1% - 11.3%). In nonhousehold settings, the secondary attack rate was higher for VUI-21OCT-01 than other Delta cases, but this difference was not significant."17:10
de-factoso that would mean for one generation (roughly 4.5 days on average): 12.2/11.2 ~ 1.089 hence +8.9% higher reproduction17:13
de-factosdfgsdfg, ^^17:19
de-factoprevious report under https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/1028113/Technical_Briefing_26.pdf17:20
de-facto.title https://www.medrxiv.org/content/10.1101/2021.10.27.21265563v117:29
Brainstormde-facto: From www.medrxiv.org: COVCOG 2: Cognitive and Memory Deficits in Long COVID: A Second Publication from the COVID and Cognition Study. | medRxiv17:29
de-facto.title https://www.medrxiv.org/content/10.1101/2021.10.26.21265525v217:31
Brainstormde-facto: From www.medrxiv.org: COVCOG 1: Factors predicting Cognitive Symptoms in Long COVID. A First Publication from the COVID and Cognition Study | medRxiv17:31
BrainstormNew from LitCovid: (news): Impact of the Coronavirus on Providing Oral Health Care in the Netherlands. → https://www.ncbi.nlm.nih.gov/research/coronavirus/publication/3470682617:34
BrainstormUpdates for Netherlands: +7412 cases (now 2.2 million), +13 deaths (now 18823) since 17 hours ago — Dominican Rep.: +879 cases (now 380215), +2 deaths (now 4126), +7456 tests (now 2.2 million) since 23 hours ago17:37
de-facto.title https://www.nejm.org/doi/full/10.1056/NEJMoa211422817:54
Brainstormde-facto: From www.nejm.org: Waning Immunity after the BNT162b2 Vaccine in Israel | NEJM17:54
de-facto.title https://www.medrxiv.org/content/10.1101/2021.10.25.21265500v117:56
Brainstormde-facto: From www.medrxiv.org: Third doses of COVID-19 vaccines reduce infection and transmission of SARS-CoV-2 and could prevent future surges in some populations | medRxiv17:56
BrainstormNew from EMA: Human medicine assessment reports: (news): Human medicines European public assessment report (EPAR): Spikevax (previously COVID-19 Vaccine Moderna), COVID-19 mRNA Vaccine (nucleoside modified), COVID-19 virus infection, Date of authorisation: 06/01/2021, Revision: 14, Status: Authorised → https://www.ema.europa.eu/en/medicines/human/EPAR/spikevax18:06
BrainstormNew from COVID tweets: Brian Hjelle, virologist (@hjelle_brian): Absolutely 💯 good idea to find those needle-in-haystack rare people who "can't get COVID". Those CCR5, resistant knockouts proved very helpful in HIV drug development.nature.com/articles/d4158… → https://twitter.com/hjelle_brian/status/145411866910192025718:17
BrainstormNew from COVID tweets: Brian Hjelle, virologist (@hjelle_brian): The trick, as Mary Claire King taught all when she found the BRCA gene, is to be RUTHLESSLY stringent. In this case look for those rare schmucks who walked into a beehive of COVID and repeatedly emerged unscathed. We're just here for your DNA, pal. → https://twitter.com/hjelle_brian/status/145412126922639769918:27
BrainstormUpdates for Italy: +5332 cases (now 4.8 million), +33 deaths (now 132037), +474778 tests (now 103.4 million) since a day ago — Greece: +3611 cases (now 734778), +55 deaths (now 15856), +254613 tests (now 25.6 million) since a day ago — United Kingdom: +40014 cases (now 9.0 million), +6206287 tests (now 331.7 million) since 22 hours ago [... want %more?]18:39
BrainstormNew from r/WorldNews: worldnews: Russia Suffers Deadliest September Since World War II With Covid Untamed → https://old.reddit.com/r/worldnews/comments/qigsc0/russia_suffers_deadliest_september_since_world/18:48
BrainstormNew from COVID tweets: Pierre A Fournier (@pafournier): No efficacy against infection detected after 7 months in Sweden, but protection against severe COVID disease last longer (42% after 6 months).This is important data. I wish we had similar data for post-infection immunity. twitter.com/x2IndSpeculato… → https://twitter.com/pafournier/status/145413109006764851619:10
de-facto.title https://www.nature.com/articles/s41586-021-04142-619:15
Brainstormde-facto: From www.nature.com: Untimely TGFβ responses in COVID-19 limit antiviral functions of NK cells | Nature19:15
de-facto"NK cell function may be altered during COVID-19 despite increased representation of NK cells with an activated and ‘adaptive’ phenotype3,4. Here we show that viral load decline in COVID-19 correlates with NK cell status and that NK cells can control SARS-CoV-2 replication by recognizing infected target cells."19:16
de-facto"In severe COVID-19, NK cells show remarkable defects in virus control, cytokine production and cell-mediated cytotoxicity despite high expression of cytotoxic effector molecules. Single-cell RNA-sequencing (scRNA-seq) of NK cells along the time course of the entire COVID-19 disease spectrum reveals a unique gene expression signature."19:17
de-facto"Transcriptional networks of interferon-driven NK cell activation are superimposed by a dominant TGFβ response signature with reduced expression of genes related to cell-cell adhesion, granule exocytosis and cell-mediated cytotoxicity."19:17
de-facto"In severe COVID-19, serum levels of TGFβ peak during the first 2 weeks of infection, and serum obtained from these patients profoundly inhibits NK cell function in a TGFβ-dependent manner. "19:18
de-facto"Our data reveal that untimely production of TGFβ is a hallmark of severe COVID-19 and may inhibit NK cell function and early virus control."19:18
de-factothis potentially could be big19:19
BrainstormNew from Gazzetta Ufficiale italiana: MINISTERO DELLE INFRASTRUTTURE E DELLA MOBILITA' SOSTENIBILI - DECRETO 18 ottobre 2021: Cessazione degli effetti del decreto 12  febbraio  2020,  concernentel'imposizione di oneri di  servizio  pubblico  sui  collegamenti  tral'aeroporto di Comiso e gli scali aeroportuali [... want %more?] → http://www.gazzettaufficiale.it/eli/id/2021/10/29/21A06365/SG19:20
BrainstormUpdates for India: +14160 cases (now 34.3 million), +551 deaths (now 457772) since 19 hours ago — Spain: +2248 cases (now 5.0 million), +50 deaths (now 87372) since 23 hours ago — Jordan: +1454 cases (now 859796), +16 deaths (now 11016), +31398 tests (now 10.9 million) since a day ago — Canada: +2644 cases (now 1.7 million), +41 deaths (now 28982) since 23 hours ago19:29
BrainstormNew from COVID tweets: Eric Topol (@EricTopol): Disconcerting to see many countries in Europe starting to heat up again, possibly reflecting, at least in part, some waning of vaccine effectiveness pic.twitter.com/Pf3ZGcW0Qg → https://twitter.com/EricTopol/status/145413765187171123219:31
BrainstormNew from COVID tweets: Eric Topol (@EricTopol): Striking increase in risk of *Unvaccinated, Prior Covid* across the age groups, vaccines, variants, time of prior infection ranging from 2.5 to 19.5-fold pic.twitter.com/Hh2Khu58Bz → https://twitter.com/EricTopol/status/145414000058545766819:41
BrainstormNew from COVID tweets: Prof Francois Balloux (@BallouxFrancois): The best we can do, I believe, is to smoothen the transition of the virus into endemicity, try to reduce harm through primarily light-touch measures, and avoid adding to the pandemic's toll by implementing impetuous, poorly thought-out interventions.6/ → https://twitter.com/BallouxFrancois/status/145414228099516416719:52
BrainstormNew from Johnson&Johnson: (news): Statement on Data Published in PLOS Medicine on Tolerability and Immune Response of Johnson & Johnson Ebola Vaccine Regimen in Adults Living with HIV → https://www.jnj.com/statement-on-data-published-in-plos-medicine-on-tolerability-and-immune-response-of-johnson-johnson-ebola-vaccine-regimen-in-adults-living-with-hiv20:02
BrainstormUpdates for Mali: +53 cases (now 15978), +2 deaths (now 563), +3373 tests (now 452198) since 23 hours ago — Greenland: +12 cases (now 799), +423 tests (now 87340) since 22 hours ago20:06
BrainstormNew from CIDRAP: COVID-19 Scan for Oct 29, 2021: Cancer patients and COVID-19 COVID relief recommendations → https://www.cidrap.umn.edu/news-perspective/2021/10/covid-19-scan-oct-29-202120:23
BrainstormNew from COVID tweets: Eric Topol (@EricTopol): Bottom line: "natural immunity" is unreliable, provides relatively protection on its own compared with vaccination.But Prior Covid + 1 dose ("hybrid immunity") vaccine provides better protection than any 2-dose vaccine combo, which a large body of data supports. → https://twitter.com/EricTopol/status/145415316363256627920:34
BrainstormNew from COVID tweets: Brian Hjelle, virologist (@hjelle_brian): Maybe there should be no-vax communities where unvaxed cops spew viruses upon unvaxed horse-pasties, and they can go to hospitals where unvaxed HCW can share variants with COVIDy RWNJ radio hosts and the like. All in isolation. → https://twitter.com/hjelle_brian/status/145415897114145177620:55
BrainstormNew from StatNews: Politics: Can a pro-Covid vaccine, anti-mandate position help a Republican win in a Democratic state? → https://www.statnews.com/2021/10/29/pro-vaccine-anti-mandate-republican-glenn-youngkin/21:05
BrainstormNew from FDA Press Releases: FDA: FDA Authorizes Pfizer-BioNTech COVID-19 Vaccine for Emergency Use in Children 5 through 11 Years of Age → http://www.fda.gov/news-events/press-announcements/fda-authorizes-pfizer-biontech-covid-19-vaccine-emergency-use-children-5-through-11-years-age21:16
BrainstormNew from StatNews: FDA authorizes Pfizer Covid-19 vaccine for children aged 5 to 11: The FDA granted emergency use authorization to the Covid-19 vaccine developed by Pfizer and its partner BioNTech for children ages 5 to 11. → https://www.statnews.com/2021/10/29/fda-pfizer-vaccine-covid19-children/21:37
BrainstormNew from WebMD: Deadline Looms for Unvaccinated Air Force Personnel: Air Force personnel face disciplinary action if they don't get vaccinated, while a judge in Washington, D.C., blocked the White House from enforcing some mandates and a judge in New York upheld the city's [... want %more?] → https://www.webmd.com/vaccines/covid-19-vaccine/news/20211029/vaccine-mandates-face-challenges21:47
BrainstormUpdates for Kuwait: +22 cases (now 412641), +17084 tests (now 4.8 million) since 23 hours ago22:11
BrainstormUpdates for Canada: +2795 cases (now 1.7 million), +38 deaths (now 28984) since 23 hours ago — United Kingdom: +186 deaths (now 140814) since 22 hours ago22:35
BrainstormNew from COVID tweets: Prof Francois Balloux (@BallouxFrancois): I find it frustrating that the massive UK COVID19 epidata released to the public seems to generate more confusion and conspiracies than insight. I feel bad about stating this as a believer in transparency, but maybe, most humans might not be [... want %more?] → https://twitter.com/BallouxFrancois/status/145418436479589172522:41
BrainstormNew from COVID tweets: Marc Veldhoen (@Marc_Veld): As per CDC report; vaccines remain working!nytimes.com/interactive/20… → https://twitter.com/Marc_Veld/status/145418701569670349322:51
BrainstormNew from BBC Health: Covid vaccines: FDA approves Pfizer jabs for children 5 and up: The decision means 28 million US children between the ages of five and 11 may soon be eligible for Covid jabs. → https://www.bbc.co.uk/news/world-us-canada-5904485323:02
BrainstormNew from COVID tweets: Brian Hjelle, virologist (@hjelle_brian): We're all influenced by our life experiences. Mine included seeing young people die of viral diseases like hemorrhagic fever.One reason I don't screw around with stuff like COVID. → https://twitter.com/hjelle_brian/status/145419354207139430623:12
BrainstormNew from COVID19 Vaccine Tracker: Mark Root-Wiley: Aivita Biomedical Inc: AV-COVID-19 → https://covid19.trackvaccines.org/vaccines/74/23:23
BrainstormNew from COVID19 Vaccine Tracker: Mark Root-Wiley: AnGes: AG0302-COVID19 → https://covid19.trackvaccines.org/vaccines/31/23:33
BrainstormNew from CIDRAP: COVID vaccines protect against Delta but don't fully stop disease spread: Mary Van Beusekom | News Writer | CIDRAP News Oct 29, 2021 The secondary attack rate was 25% in fully vaccinated people and 38% in the unvaccinated. → https://www.cidrap.umn.edu/news-perspective/2021/10/covid-vaccines-protect-against-delta-dont-fully-stop-disease-spread23:54

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