| Dredd | hello LjL 👋 | 00:00 |
|---|---|---|
| LjL-Matrix | hi Dredd | 00:00 |
| Brainstorm | Updates for Argentina: +1440 cases (now 5.3 million), +26 deaths (now 116055), +99006 tests (now 25.3 million) since a day ago | 00:06 |
| Brainstorm | New from COVID tweets: Michael Lin, PhD-MD 🧬 (@michaelzlin): I know there are people who think MG is just trying the way she sees best to earn people's sympathies for minimal things like vaccination, but appeasing anti-preventionists is not the way to do it. → https://twitter.com/michaelzlin/status/1456395791359111168 | 00:06 |
| Brainstorm | Updates for Faroe Is.: +111 cases (now 2484), +1 deaths (now 5), +8000 tests (now 499000) since 23 hours ago — Bulgaria: +4662 cases (now 623946), +166 deaths (now 24755), +79276 tests (now 5.7 million) since 23 hours ago | 00:30 |
| Brainstorm | New from The Lancet (Online): [Comment] Financing sustainable health systems for the next decade: In The Lancet, Gloria Ikilezi and colleagues1 estimated annual spending on immunisation by governments, households, and donors for 135 low-income and middle-income countries (LMICs) between [... want %more?] → https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(21)01828-6/fulltext | 00:38 |
| pure{blood}conju | https://odysee.com/@EfektSetnejMaply:4/zelenko_pl:5?fbclid=IwAR1R3a2AF2SCIV2vcx1B-3lzAzQnLAWjLiiJrL1Oz3nbBmmHwaikvW_tHLg | 00:45 |
| pure{blood}conju | Watch & Share 👊😎👍 | 00:45 |
| Dredd | What is this? | 00:48 |
| de-facto | pure{blood}conju, whats the message of that video? | 00:55 |
| pure{blood}conju | de-facto: You'll find out. Watch. He was a private doctor of Trump for example. He says out loud what is happening with covid and vaccines | 00:59 |
| Brainstorm | New from r/WorldNews: worldnews: Covid has caused 28m years of life to be lost, study finds → https://old.reddit.com/r/worldnews/comments/qmxvuq/covid_has_caused_28m_years_of_life_to_be_lost/ | 00:59 |
| de-facto | i dont care what he claims to be, i only care about his intention | 00:59 |
| de-facto | if he already begins with underlining his credibility i suspect he will say things that undermine that | 01:00 |
| de-facto | what is his claim? | 01:00 |
| de-facto | pure{blood}conju, do you want to discuss content? | 01:04 |
| de-facto | pure{blood}conju, what is your opinion about that video there | 01:09 |
| Brainstorm | New from COVID tweets: Brian Hjelle, virologist (@hjelle_brian): To 5 to 11 year olds newly going out for vaccine.Will never know hardly any of you, but you are heroes.Thank you for caring about our world. → https://twitter.com/hjelle_brian/status/1456411820214816787 | 01:09 |
| pure{blood}conju | He's just saying out loud what's happening in a world. You don't need to watch it if you don't want to or you get paid to decline current genocide. | 01:10 |
| de-facto | what genocide are you talking about? | 01:10 |
| pure{blood}conju | ...watch... | 01:12 |
| de-facto | how do you explain that when comparing the attack rates (number of cases) in two groups, vaccinated with non-vaccinated, that infections and severe progressions as well as deaths are significantly lowered in the vaccinated groups? | 01:13 |
| pure{blood}conju | de-facto: 🤣 you made my day 😁 | 01:14 |
| de-facto | have you looked at the statistics? | 01:15 |
| Dredd | This isn't really a room for the more fringe opinions on vaccinations and such | 01:17 |
| de-facto | pure{blood}conju, to be clear we do not welcome antivax-propaganda, although we openly discuss based on *data* | 01:17 |
| pure{blood}conju | de-facto: Yeas I have. | 01:17 |
| pure{blood}conju | On your shares as well | 01:18 |
| Dredd | You will have to actually discuss what you're claiming / the video is claiming here. You can't just say "watch" | 01:18 |
| Dredd | de-facto is being very patient 😀 | 01:19 |
| dTal | "genocide" lolwhut | 01:20 |
| specing | these antivaxxers always start by linking some video and call us to watch it, while providing no input whatsoever | 01:21 |
| dTal | here let me eagerly click on a video linked by someone who is clearly hysterical, and thinks "Trump's personal doctor" is some kind of acclaimation | 01:21 |
| dTal | NOT | 01:21 |
| pure{blood}conju | This video will also explain why "your" statistics say what they say and what doctors say about their covid deaths reports magically getting rejected or deleted by the system. You can easily contact dr. Zelenco by email. | 01:21 |
| dTal | you can easily go jump in a lake | 01:22 |
| Dredd | dTal be nice 😛 | 01:22 |
| dTal | awwww do I have to | 01:22 |
| dTal | I've lost patience with this shit | 01:22 |
| Dredd | pure{blood}conjure: is that reason something along the lines of "they're lying"? | 01:22 |
| dTal | they don't put in any effort, why should I | 01:22 |
| Dredd | And again you call us to watch the video | 01:22 |
| Dredd | I don't have a good answer 😛 | 01:23 |
| Dredd | I strongly suspect no one is going to watch the video | 01:23 |
| dTal | I suspect the reason they always want us to watch their videos is because they are memetic cognitohazards | 01:25 |
| dTal | they can't explain their opinions because they don't understand why they have them | 01:26 |
| Dredd | Maybe only if you are susceptible? 😀 | 01:26 |
| dTal | all they know is that they watched a video, and after they watched the video the were convinced | 01:26 |
| Dredd | Honestly I think SCP stuff sounds more real than some of what I hear from anti-vaxxers at times | 01:26 |
| Dredd | I like the one with the infinite ikea | 01:27 |
| specing | I'm not going to watch any videos | 01:27 |
| specing | "memetic cognitohazards" hahahahah! | 01:27 |
| dTal | I'm serious. After they watch the video, they have an overwhelming desire to convince other people to watch that video | 01:27 |
| dTal | it's a memetic virus | 01:27 |
| dTal | the video will say absolutely anything to achieve that effect | 01:28 |
| specing | LIKE AND SHARE!!! | 01:28 |
| * specing greatly prefers "question and understand!!!" | 01:29 | |
| Brainstorm | New from COVID tweets: Eric Topol (@EricTopol): Addressing #CovidisAirborne with sciencepnas.org/content/118/45…proceedings of a workshop with the experts @PNASNews w/ @Smogdr @linseymarr @kprather88 @Lakdawala_Lab @Prof_Lowe pic.twitter.com/xdjjFZ8Uto → https://twitter.com/EricTopol/status/1456416187370278915 | 01:30 |
| Brainstorm | New from COVID tweets: Eric Topol (@EricTopol): As #SARSCoV2 evolves, there are thousands of sequence changes and variants. A huge unmet challenge is for a rapid assessment of whether there are functional changes indicative of increased fitness.Until today. @ScienceMagazine @doudna_lab @TheOttLab [... want %more?] → https://twitter.com/EricTopol/status/1456419311069794305 | 01:41 |
| Brainstorm | Updates for Barbados: +336 cases (now 19188), +3 deaths (now 167), +2096 tests (now 396380) since a day ago | 02:17 |
| Brainstorm | New from r/WorldNews: worldnews: Gene Found In South Asians Double The Risk Of COVID-19 Death: Study → https://old.reddit.com/r/worldnews/comments/qmzquf/gene_found_in_south_asians_double_the_risk_of/ | 02:23 |
| Brainstorm | Updates for Uruguay: +236 cases (now 394679), +2 deaths (now 6082), +12520 tests (now 3.9 million) since 23 hours ago — Zimbabwe: +21 cases (now 133112), +1 deaths (now 4685), +3104 tests (now 1.5 million) since 23 hours ago | 02:30 |
| Brainstorm | Updates for Guadeloupe: +200 cases (now 54737), +28023 tests (now 523309) since 8 days ago | 03:07 |
| Brainstorm | New from COVID tweets: Eric Topol (@EricTopol): Sad to see that @NFL leading QB, @AaronRodgers12, had homeopathic treatment and claimed he was "immunized," never got vaccinated, now has Covid. Puts his team in jeopardy and is a negative role model for Americans. → https://twitter.com/EricTopol/status/1456445536328830982 | 03:28 |
| Brainstorm | Updates for Curacao: +12 cases (now 17123), +1273 tests (now 317067) since 22 hours ago — Guinea-Bissau: +5 cases (now 6149), +1 deaths (now 143), +519 tests (now 103298) since 5 hours ago | 03:32 |
| Brainstorm | New from The Indian Express: World: WHO: Europe is the epicenter of pandemic despite vaccines → https://indianexpress.com/article/world/who-europe-is-the-epicenter-of-pandemic-despite-vaccines-7607843/ | 03:38 |
| lastshell | cases and hospitalizations are rising in my county, currently in NV state | 03:50 |
| lastshell | people don't care anymore in the store they put signs of wear a mask, but you can see some people indoor without mask our using as a chin diapper | 03:50 |
| specing | the pandemic effectively ended for the vast majority of vaccinated | 03:51 |
| lastshell | also big holidays are a head, thanksgiving, xmas and new year | 03:51 |
| specing | so, why would they follow any rules? | 03:51 |
| lastshell | but specing I recall inmunity fall after 6 months | 03:51 |
| specing | so what, you can easily get boosters now | 03:52 |
| lastshell | I'm kind of thinking if I need or not need a booster | 03:53 |
| lastshell | I been exercising since last year almost daily | 03:54 |
| specing | long covid can still ruin your life | 03:54 |
| lastshell | I know that, but worry we ended with vaccines every 6 months | 03:55 |
| lastshell | that will not cause to build antibody resistance ? | 03:58 |
| Brainstorm | New from COVID tweets: The New York Times (@nytimes): Breaking News: The U.S. government canceled its contract with Emergent, a troubled Covid vaccine manufacturer that ruined millions of doses earlier this year. nyti.ms/2ZQM8kf → https://twitter.com/nytimes/status/1456452059310575618 | 04:00 |
| specing | yes, and if something more dangerous than delta comes up, boosters more frequently | 04:00 |
| lastshell | :( | 04:00 |
| de-facto | the shorter the serial time (between two hosts in infection chains) the faster antigenic drift (e.g. with more fit variants more virions are produced per unit time, such as delta) | 04:05 |
| de-facto | yet the fewer hosts are infected, the less parallel bruteforcing on optimizing fitness under currently most wide spread selection pressure | 04:06 |
| lastshell | de-facto you guys are not worries about antibody resistance ? | 04:08 |
| Brainstorm | Updates for New Zealand: +165 cases (now 7138), +1 deaths (now 29), +28890 tests (now 4.2 million) since 22 hours ago | 04:09 |
| de-facto | hence we should end as many infection chains as possible, hence whatever was optimized during the breed cycle in that host gets lost by not being able to carry on to the next susceptible | 04:10 |
| de-facto | also repeating vaccinations not only kicks up antibody levels again, to the immune system that looks like a breakthrough infection (large amounts of the antigen being presented by the vaccination) so it will try to broaden the variety of antibody spectrum to rise the probability to bind to more variants of the antigen | 04:13 |
| de-facto | i am not quite sure to what degree that takes place, but in many of the booster papers testing the antibody neutralization titers against a spectrum of variants (e.g. D614G, B.1.1.7, B.1.351, B.1.617.2, etc) reaches more equal values than before, hence is "less specific" to variants (i think because of broader variety in affinity) | 04:18 |
| specing | According to news, we might be the only country in the EU to go into lockdown in the next days :D | 04:20 |
| de-facto | i would guess the best would be to stimulate the immune system with a wider variety of antigen, e.g. having multivalent vaccines containing signatures of the spike protein for all current VoCs, iirc those induced higher neutralization to every single variant | 04:20 |
| de-facto | so there probably are some synergetic effects at play, maybe binding to more conserved regions of the antigen (the similarities in all of the stimulating spectrum presented)? | 04:21 |
| de-facto | .title https://www.pnas.org/content/118/29/e2102775118 | 04:29 |
| Brainstorm | de-facto: From www.pnas.org: Scalable live-attenuated SARS-CoV-2 vaccine candidate demonstrates preclinical safety and efficacy | PNAS | 04:29 |
| de-facto | this is quite interesting, there is some freedom of choice in encoding the same protein in RNA, hence also to deoptimize it (make it less efficient), together with deleting or inactivating some parts this could make SARS-CoV-2 much less virulent, hence potentially a live attenuated vaccine candidate for intranasal application | 04:31 |
| de-facto | .title https://clinicaltrials.gov/ct2/show/NCT04619628 | 04:32 |
| Brainstorm | de-facto: From clinicaltrials.gov: Safety and Immunogenicity of COVI-VAC, a Live Attenuated Vaccine Against COVID-19 - Full Text View - ClinicalTrials.gov | 04:32 |
| Brainstorm | Updates for Peru: +1114 cases (now 2.2 million), +24 deaths (now 200350), +43508 tests (now 19.2 million) since 23 hours ago — Netherlands: +10242 cases (now 2.2 million) since 21 hours ago | 04:40 |
| Brainstorm | New from The Indian Express: World: Novavax completes process for WHO emergency use approval of Covid-19 vaccine → https://indianexpress.com/article/world/novavax-completes-process-for-who-emergency-use-approval-of-covid-19-vaccine-7607916/ | 04:52 |
| Brainstorm | New from Science-Based Medicine: Children, Underlying Conditions, and COVID-19: That we can identify children who have a higher risk for severe outcomes shouldn't be used to minimize the virus and argue against vaccination in healthy children. Rather, we should recognize there are populations of [... want %more?] → https://sciencebasedmedicine.org/children-underlying-conditions-and-covid-19/ | 05:13 |
| Brainstorm | New from Reddit (test): CoronaVirus_2019_nCoV: U.K. becomes first country to approve Merck's Covid-19 antiviral pill → https://old.reddit.com/r/CoronaVirus_2019_nCoV/comments/qn3095/uk_becomes_first_country_to_approve_mercks/ | 05:24 |
| Brainstorm | Updates for Germany: +37640 cases (now 4.7 million) since 23 hours ago — Belgium: +10190 cases (now 1.4 million), +22 deaths (now 26105) since 23 hours ago | 05:30 |
| Brainstorm | New from The Indian Express: World: France’s average daily new Covid infections at a 6-week high → https://indianexpress.com/article/world/frances-average-daily-new-covid-infections-at-a-6-week-high-7607985/ | 05:55 |
| Brainstorm | Updates for Somalia: +695 cases (now 22693), +86 deaths (now 1294), +22846 tests (now 262138) since 10 days ago | 06:07 |
| Brainstorm | Updates for Poltava Oblast, Ukraine: +1197 cases (now 102945), +34 deaths (now 2435) since 23 hours ago — Unknown, Netherlands: +120 cases (now 7430) since 23 hours ago — W.P. Labuan, Malaysia: +19 cases (now 10096) since 23 hours ago — Lombardy, Italy: +745 cases (now 896409), +15 deaths (now 34187) since 23 hours ago | 06:32 |
| Brainstorm | New from The Indian Express: World: Center of Italy’s anti-vaccine protests is now a Covid hot spot → https://indianexpress.com/article/world/italy-anti-covid-19-vaccine-protest-now-hot-spot-7608090/ | 07:08 |
| Brainstorm | Updates for Kyrgyzstan: +78 cases (now 181668), +2 deaths (now 2681), +2894 tests (now 1.8 million) since a day ago | 07:09 |
| Brainstorm | Updates for India: +12729 cases (now 34.3 million) since 15 hours ago | 07:34 |
| Brainstorm | New from r/Coronavirus: Daily Discussion Thread | November 05, 2021: Please refer to our Wiki for more information on COVID-19 and our sub. You can find answers to frequently asked questions in our FAQ , where there is valuable information such as our: → https://old.reddit.com/r/Coronavirus/comments/qn5er2/daily_discussion_thread_november_05_2021/ | 08:01 |
| sKep | %cases | 08:21 |
| Brainstorm | sKep: Sorry, not found. Either there aren't cases, or it's under a different name. | 08:21 |
| sKep | %cases India | 08:21 |
| Brainstorm | sKep: India has had 34.3 million confirmed cases (2.5% of all people) and 459875 deaths (1.3% of cases) as of 47 minutes ago. 611.3 million tests were done (5.6% positive). 738.5 million were vaccinated (54.3%). +12729 cases since 15 hours ago. See https://www.mygov.in/covid-19 or https://www.covid19india.org/ | 08:22 |
| sKep | %cases russia | 08:22 |
| Brainstorm | sKep: Russia has had 8.7 million confirmed cases (5.9% of all people) and 243255 deaths (2.8% of cases) as of 22 hours ago. 216.0 million tests were done (4.0% positive). 56.7 million were vaccinated (38.6%). +40217 cases, +1195 deaths since 23 hours ago. See https://offloop.net/covid19/?default=Russia | 08:22 |
| Brainstorm | sKep: If you know of an official or otherwise good site for data about Russia, with a reasonably short URL, please %tell LjL about it. | 08:22 |
| Brainstorm | New from The Indian Express: Climate Change: A nuclear-powered shower? Russia tests a climate innovation → https://indianexpress.com/article/world/climate-change/a-nuclear-powered-shower-russia-tests-a-climate-innovation-7608185/ | 08:42 |
| Brainstorm | New from r/WorldNews: worldnews: Chinese journalist jailed over Covid reporting is ‘close to death’, family say → https://old.reddit.com/r/worldnews/comments/qn5vzu/chinese_journalist_jailed_over_covid_reporting_is/ | 08:54 |
| Brainstorm | Updates for Georgia: +5340 cases (now 743511), +62 deaths (now 10300), +55301 tests (now 10.5 million) since a day ago | 09:08 |
| Brainstorm | Updates for Czechia: +8447 cases (now 1.8 million), +60 deaths (now 30938), +85618 tests (now 41.0 million) since a day ago — Armenia: +1835 cases (now 316839), +50 deaths (now 6582), +11533 tests (now 2.2 million) since a day ago | 09:32 |
| Brainstorm | New from StatNews: Opinion: Is the debate over the origin of Covid-19 still worth having?: However Covid-19 originated, enough knowledge has already been accumulated that can reduce the risks of further pandemics. Applying those insights should be the priority moving forward. → https://www.statnews.com/2021/11/05/is-debate-about-origin-of-covid-19-still-worth-having/ | 09:49 |
| Brainstorm | New from The Indian Express: World: Pacific islanders struggle at COP26 climate summit as pandemic keeps leaders away → https://indianexpress.com/article/world/pacific-islanders-struggle-at-cop26-climate-summit-as-pandemic-keeps-leaders-away-7608296/ | 09:59 |
| Brainstorm | Updates for Hungary: +6804 cases (now 892164), +83 deaths (now 31184), +32685 tests (now 7.5 million) since a day ago — Lithuania: +3282 cases (now 421360), +37 deaths (now 6047), +22268 tests (now 5.7 million) since a day ago — Taiwan: +7 cases (now 16437), +14518 vaccines (now 17.4 million), +87211 tests (now 7.7 million) since a day ago | 10:10 |
| Brainstorm | New from COVID tweets: Marc Veldhoen (@Marc_Veld): Safety and Efficacy of the BNT162b2 mRNA Covid-19 Vaccine through 6 MonthsThrough 6 months of follow-up and despite a gradual decline in vaccine efficacy, BNT162b2 had a favorable safety profile and was highly efficacious in preventing Covid-19.nejm.org/doi/full/10.10… → https://twitter.com/Marc_Veld/status/1456548407342997542 | 10:10 |
| Brainstorm | New from The Indian Express: World: US cancels vaccine maker’s multimillion dollar deal, says report → https://indianexpress.com/article/world/us-johnson-johnson-covid-vaccine-maker-emergent-biosolutions-7608402/ | 10:21 |
| Brainstorm | New from The Indian Express: World: Joe Biden sets Covid-19 vaccine rules for businesses, prompting Republican backlash → https://indianexpress.com/article/world/united-states-covid-vaccine-rules-businesses-7608418/ | 10:31 |
| Brainstorm | Updates for Austria: +9799 cases (now 865390), +32 deaths (now 11451), +473302 tests (now 99.4 million) since 23 hours ago — Estonia: +1435 cases (now 202629), +7 deaths (now 1581), +7818 tests (now 2.2 million) since a day ago — Germany: +37072 cases (now 4.7 million) since 20 hours ago | 10:41 |
| Brainstorm | New from EMA: What's new: Medicine: Human medicines European public assessment report (EPAR): Comirnaty, COVID-19 mRNA vaccine (nucleoside-modified), COVID-19 virus infection, Date of authorisation: 21/12/2020, Revision: 14, Status: Authorised → https://www.ema.europa.eu/en/medicines/human/EPAR/comirnaty | 11:04 |
| Brainstorm | Updates for Slovakia: +6805 cases (now 506795), +20 deaths (now 13166), +20519 tests (now 4.0 million) since a day ago | 11:12 |
| Brainstorm | New from Politico: Coronavirus: Belgian health minister urges people to work from home amid COVID surge → https://www.politico.eu/article/belgium-coronavirus-cases-work-from-home/ | 11:15 |
| Brainstorm | New from EMA: What's new: Medicine: Veterinary medicines European public assessment report (EPAR): Vepured, E. coli verotoxoid vaccine (inactivated recombinant), Date of authorisation: 17/08/2017, Revision: 3, Status: Authorised → https://www.ema.europa.eu/en/medicines/veterinary/EPAR/vepured | 11:26 |
| Brainstorm | New from StatNews: Experimental Pfizer pill prevents Covid hospitalizations and deaths: An experimental antiviral pill from Pfizer reduced Covid patients' risk of death and hospitalization by 89% in a large study, the company said Friday. → https://www.statnews.com/2021/11/05/experimental-pfizer-pill-prevents-covid-hospitalizations-and-deaths/ | 11:58 |
| Brainstorm | Updates for Poland: +15905 cases (now 3.1 million), +152 deaths (now 77547), +157440 tests (now 22.5 million) since a day ago — Finland: +788 cases (now 162476), +9982 tests (now 7.5 million) since 22 hours ago | 12:02 |
| Brainstorm | New from r/WorldNews: worldnews: New COVID-19 pill cut hospital, death risk by 90% → https://old.reddit.com/r/worldnews/comments/qn8o9a/new_covid19_pill_cut_hospital_death_risk_by_90/ | 12:21 |
| Brainstorm | New from COVID tweets: Anthony J Leonardi, PhD, MS (@fitterhappierAJ): The Pfizer news is probably some of the best news in the last 8 months1) Good efficacy2) not mutagenic3) Potential for ProphylaxisBUT...There is a manufacturing bottleneck.bloomberg.com/news/articles/… twitter.com/T66367354/stat… → https://twitter.com/fitterhappierAJ/status/1456587110304129031 | 12:43 |
| Brainstorm | Updates for Croatia: +6932 cases (now 490074), +36 deaths (now 9400), +15079 tests (now 3.2 million) since 23 hours ago — Netherlands: +45 cases (now 2.2 million) since 19 hours ago | 12:45 |
| Brainstorm | New from NPR: Pfizer says its COVID-19 pill cuts disease's worst risks by 89%: Based on the strength of the trial's results, Pfizer says it will ask the FDA for emergency use authorization rather than enroll more people for clinical trials. → https://www.npr.org/sections/coronavirus-live-updates/2021/11/05/1052679112/pfizer-covid-pill-treatment | 13:05 |
| Brainstorm | Updates for Laos: +959 cases (now 45020), +1 deaths (now 77), +8394 tests (now 674003) since a day ago — Indonesia: +518 cases (now 4.2 million), +19 deaths (now 143519), +195598 tests (now 47.9 million) since a day ago — Nepal: +174 cases (now 814289), +2 deaths (now 11438), +2307 tests (now 4.4 million) since 23 hours ago [... want %more?] | 13:16 |
| Brainstorm | New from COVID tweets: John Burn-Murdoch (@jburnmurdoch): Of course one difference here is that vaccine coverage in western Europe is now at similar levels in all age-groups, and we would expect that alone to reduce the youth-skewed case distribution.Nonetheless, seeing strong rises across all age-groups is a problem. → https://twitter.com/jburnmurdoch/status/1456593868468674566 | 13:17 |
| Brainstorm | New from COVID tweets: Eric Topol (@EricTopol): Big and very positive news today on Pfizer's anti-Covid pill --Paxlovid --that reduced hospitalization and death by 89%, taken within 3 days of diagnosis👍wsj.com/articles/pfize… @JaredSHopkins This week's @ScienceMagazine paper below on the 2nd such pill [... want %more?] → https://twitter.com/EricTopol/status/1456597579169361923 | 13:28 |
| Brainstorm | Updates for Belarus: +1991 cases (now 610022), +16 deaths (now 4712), +34885 tests (now 9.8 million) since a day ago — United Kingdom: +36940 cases (now 9.3 million) since 21 hours ago | 13:35 |
| Brainstorm | New from COVID tweets: Marc Veldhoen (@Marc_Veld): A potential very important medicine against CPVOD-19Pfizer's anti-Covid pill - Paxlovid - can reduce hospitalization and death by 89%, when taken within 3 days of COVID-19 diagnosiswsj.com/articles/pfize… → https://twitter.com/Marc_Veld/status/1456599802674913285 | 13:39 |
| Brainstorm | New from COVID tweets: Brian Hjelle, virologist (@hjelle_brian): Another Brian wish about to be granted. A protease inhibitor! 🎁 Pfizer says its experimental pill reduces risk of hospitalization, death from Covid-19cnn.com/2021/11/05/hea… → https://twitter.com/hjelle_brian/status/1456603453149515782 | 13:51 |
| Brainstorm | Updates for Qatar: +119 cases (now 239871), +5292 tests (now 2.9 million) since a day ago — Zambia: +37 cases (now 209852), +5875 tests (now 2.6 million) since a day ago | 14:06 |
| Brainstorm | New from COVID tweets: Brian Hjelle, virologist (@hjelle_brian): We now have or soon will:Replicase inhibitor remdesivirRNA mutagen molnupiravirEntry inhibitor MAbsAnd, a protease inhibitor pending.The potential to squelch virus in its tracks is emerging but few will be positioned to do so. → https://twitter.com/hjelle_brian/status/1456609958506610692 | 14:23 |
| Brainstorm | Updates for Switzerland: +2851 cases (now 887446) since 23 hours ago — Germany: +37615 cases (now 4.7 million) since 23 hours ago | 14:31 |
| Brainstorm | New from StatNews: Pharma: STAT+: Pharmalittle: Pfizer pill reduced deaths in newly diagnosed Covid patients; U.S. cancels contract with Emergent → https://www.statnews.com/pharmalot/2021/11/05/pfizer-covid19-pill-reduced-deaths-emergent-novavax/ | 14:35 |
| Brainstorm | New from BBC Health: (news): Covid: Pfizer says antiviral pill 89% effective in high risk cases → https://www.bbc.co.uk/news/health-59178291 | 14:46 |
| Dredd | I'm a little sad to see so many anti-vax and pro-ivermectin people on hacker news 😟 | 15:05 |
| Brainstorm | New from COVID tweets: Eric Topol (@EricTopol): My summary table comparing the new and highly effective anti-Covid pills, a vital step forward for prevailing over the pandemicNo head-to-head trial to know about true comparative efficacy, but key differences in mechanism and other features pic.twitter.com/9Bu8F4Q0FK → https://twitter.com/EricTopol/status/1456622941647478796 | 15:08 |
| Dredd | Good news about both the Merck and Pfizer drugs though | 15:16 |
| Dredd | Definitely something we need in the toolbox, though I hope they don't become a crutch to avoid iterating on the vaccines though | 15:17 |
| Dredd | Seems Pfizer one is better than the Merck one, hopefully the UK picks it up soon too | 15:18 |
| Brainstorm | Updates for Latvia: +1821 cases (now 228681), +43 deaths (now 3444), +25814 tests (now 5.1 million) since a day ago — UAE: +80 cases (now 740289), +1 deaths (now 2138), +203988 tests (now 94.6 million) since a day ago — Kenya: +76 cases (now 253737), +11767 tests (now 2.7 million) since 23 hours ago — Gibraltar: +24 cases (now 6115), +918 tests (now 390256) since a day ago | 15:33 |
| Brainstorm | New from The Atlantic: COVID-Vaccine Mandates for Kids Are Coming: COVID-19 vaccination for 5-to-11-year-olds is finally a go . But even as the emergency-use-authorization process unfolded, so too did arguments over whether kids should (or would soon) be forced into getting shots. [... want %more?] → https://www.theatlantic.com/health/archive/2021/11/kids-school-covid-vaccine-mandate/620622/ | 15:43 |
| Brainstorm | New from WebMD: For Kids Afraid of Needles, These Tips May Help Ease COVID Shots: Most kids fear needles, but a few simple steps can help your young one get their COVID-19 shots with the fewest tears. → https://www.webmd.com/vaccines/covid-19-vaccine/news/20211105/for-kids-afraid-of-needles-these-tips-may-help-ease-covid-shots | 15:54 |
| Brainstorm | New from WebMD: Breastfeeding by Moms Who've Had COVID May Help Protect Newborn: This "passive" immune protection via breastfeeding may help protect baby from COVID with antibodies from mom. → https://www.webmd.com/lung/news/20211104/breastfeeding-by-moms-whove-had-covid-may-help-protect-newborn | 16:05 |
| Brainstorm | Updates for Chile: +2510 cases (now 1.7 million), +19 deaths (now 37814), +80027 tests (now 23.8 million) since 22 hours ago — India: +195 deaths (now 459880) since 23 hours ago | 16:10 |
| Brainstorm | Updates for Canada: +2995 cases (now 1.7 million), +53 deaths (now 29173) since 17 hours ago — United Kingdom: +405 cases (now 9.3 million) since 21 hours ago | 16:35 |
| lastshell | question what is hhe diff of pfizer vs merck vmmmm | 16:55 |
| lastshell | ivermectin | 16:55 |
| lastshell | ahh sorry phone typing | 16:55 |
| Brainstorm | Updates for Jordan: +2080 cases (now 872585), +14 deaths (now 11102), +34526 tests (now 11.1 million) since 21 hours ago | 17:00 |
| Brainstorm | New from LitCovid: (news): Prevalence of Thanatophobia and Necrophobia in India during the COVID-19 Pandemic Due to Black Fungus Infections. → https://www.ncbi.nlm.nih.gov/research/coronavirus/publication/34734539 | 17:01 |
| Dredd | lastshell: Pfizer very good. Merck pretty good. Ivermectin doesn't work according to reputable things. | 17:10 |
| Brainstorm | Updates for Netherlands: +10940 cases (now 2.2 million), +20 deaths (now 18957) since 17 hours ago — Greece: +6889 cases (now 774265), +49 deaths (now 16200), +263150 tests (now 27.2 million) since a day ago | 17:37 |
| Brainstorm | New from COVID tweets: Anthony J Leonardi, PhD, MS (@fitterhappierAJ): Your favorite Covid contrarian (in favor of variolization or exposure if not novel) → https://twitter.com/fitterhappierAJ/status/1456661916315701253 | 17:44 |
| Brainstorm | Updates for Dominican Rep.: +1104 cases (now 386285), +2 deaths (now 4148), +8642 tests (now 2.2 million) since 21 hours ago — Luxembourg: +219 cases (now 82842), +3133 tests (now 3.6 million) since 23 hours ago | 18:02 |
| Brainstorm | New from WebMD: COVID Variant Tied to Heart Inflammation in Cats, Dogs: An atypical increase of myocarditis in cats and dogs is being associated with a COVID variant. → https://www.webmd.com/lung/news/20211105/covid-variant-tied-to-heart-inflammation-in-cats-dogs | 18:06 |
| Brainstorm | New from WebMD: 'This Pandemic Still Has Legs': COVID-19 Expert Q&A: Osterholm, who runs the Center for Infectious Disease Research and Policy, says President Joe Biden's vaccine mandates are key to ending the pandemic. → https://www.webmd.com/lung/news/20211105/covid-expert-q-a | 18:28 |
| lastshell | can somebody explain me the diff between pfizer / merck and ivermectin pills ? | 18:29 |
| mrdata | a horse dewormer, by any other name, would smell as sweet | 18:34 |
| lastshell | mrdata no all ivermectin is for horse dewormer | 18:38 |
| lastshell | I'm asking a legitimate question | 18:38 |
| lastshell | and Im vaccinated before you prejudge | 18:38 |
| Brainstorm | Updates for Italy: +6761 cases (now 4.8 million), +51 deaths (now 132334), +543414 tests (now 106.4 million) since a day ago — Canada: +3095 cases (now 1.7 million), +54 deaths (now 29174) since 20 hours ago | 18:40 |
| mrdata | as far as i am aware, ivermectin is problematic because of a meta-analysis that included discredited studies comprising more than 50% of the effect | 18:40 |
| mrdata | i think it was said that if you remove those discredited studies, it doesnt meet statistical significance | 18:41 |
| mrdata | so last i heard, oxford was conducting randomized controlled trials | 18:42 |
| mrdata | i havent seen results tho | 18:42 |
| mrdata | but i think everyone agrees that effective early treatments are needed | 18:44 |
| mrdata | late stage covid is horrible | 18:44 |
| mrdata | once the damage is done, it's too late | 18:44 |
| mrdata | make sure not to be zinc or vitamin D deficient | 18:46 |
| mrdata | but megadoses of supplements cant help | 18:46 |
| mrdata | a quick google search leads me to, | 18:50 |
| mrdata | https://academic.oup.com/cid/advance-article/doi/10.1093/cid/ciab591/6310839 | 18:50 |
| mrdata | and https://academic.oup.com/ofid/advance-article/doi/10.1093/ofid/ofab358/6316214 | 18:53 |
| mrdata | more recently, https://www.businessinsider.com/ivermectin-studies-for-covid-19-see-the-flawed-evidence-2021-10 | 18:55 |
| mrdata | even people arguing in favor of ivermectin or hydroxychloroquine agree that the earlier the treatment, the better | 18:56 |
| lastshell | thank you mrdata | 18:57 |
| mrdata | as an aside about the latter, if a zinc ionophore is what you need then why not choose quercetin? | 18:57 |
| haxan | not sure Zinc makes much sense | 18:58 |
| haxan | maybe for lozenges for sore throat | 18:59 |
| lastshell | for vitamin D what is best cold liver oil or just vitamin d supplements ? | 18:59 |
| Brainstorm | Updates for Spain: +3093 cases (now 5.0 million), +27 deaths (now 87504) since 23 hours ago | 19:05 |
| mrdata | i take vitamin D3 tablets, 1000 IU/day | 19:07 |
| mrdata | i'm a bit more irregular with zinc | 19:07 |
| mrdata | got 50 mg tablets and then found out they gave me side effects | 19:07 |
| mrdata | so i try to cut them in half | 19:07 |
| mrdata | which doesnt work out well. they end up pulverized | 19:08 |
| mrdata | so couple of those per week | 19:09 |
| mrdata | zinc lozenge has turned out great for sore throat, for me | 19:10 |
| Raf[m] | <lastshell> "for vitamin D what is best..." <- I like cod liver oil | 19:21 |
| Raf[m] | Seems like a nice natural source and good oil for immersion | 19:22 |
| lastshell | Raf[m] is what I took last year in winter and currently taking for this winter as well :D | 19:22 |
| Brainstorm | Updates for United Kingdom: +34102 cases (now 9.3 million), +196 deaths (now 142019) since 23 hours ago | 19:29 |
| Brainstorm | New from COVID tweets: Brian Hjelle, virologist (@hjelle_brian): Protease inhibitors like Pfizer's nascent Paxlovid (for SARS2) were game-changers, albeit expensive ones, in the US's largely successful assault on the oft-lethal persistent RNA virus HCV. pic.twitter.com/Gbdu6ilZUG → https://twitter.com/hjelle_brian/status/1456688713459650562 | 19:33 |
| Brainstorm | New from COVID tweets: Prof Francois Balloux (@BallouxFrancois): An emerging narrative that drugs, rather than vaccines or NPIs vanquished COVID19 would be an interesting twist to the endless debates of the last 18 months. It would likely also have major implications for future pandemic planning, for better or worse.2/ → https://twitter.com/BallouxFrancois/status/1456692041635803145 | 19:44 |
| Brainstorm | New from Contagion Live: Pfizer COVID-19 Antiviral Pill Significantly Reduces Hospitalizations, Death: Interim, unpublished data show PAXLOVID is associated with 89% reductions in risk of COVID-19 hospitalization or death. Pfizer is now seeking FDA emergency authorization. → https://www.contagionlive.com/view/pfizer-covid-19-antiviral-pill-significantly-reduces-hospitalizations-death | 20:15 |
| MerlinMp[m] | Not sure if this one was already posted here | 20:28 |
| MerlinMp[m] | https://www.nature.com/articles/s41588-021-00955-3 | 20:28 |
| Brainstorm | Updates for Netherlands: +10947 cases (now 2.2 million) since 20 hours ago | 20:38 |
| Dredd | https://globalnews.ca/news/8351684/bc-covid-denier-mak-parhar-dies-coroner-investigating/ | 20:52 |
| Dredd | Huh, another one bites the dust | 20:53 |
| Brainstorm | New from FDA Press Releases: FDA: Coronavirus (COVID-19) Update: November 5, 2021 → http://www.fda.gov/news-events/press-announcements/coronavirus-covid-19-update-november-5-2021 | 20:57 |
| Brainstorm | New from COVID19 Vaccine Tracker: Andy Becker: Altimmune Inc: AdCOVID → https://covid19.trackvaccines.org/vaccines/75/ | 21:18 |
| Brainstorm | New from COVID tweets: Brian Hjelle, virologist (@hjelle_brian): Expect the white-tail deer SARS2 epizootic to extend thruout the range of the host, til proven otherwise. Expect mulies will also have it- and other ungulates, cervids? twitter.com/KidinaSandbox/… → https://twitter.com/hjelle_brian/status/1456720075533144067 | 21:39 |
| Brainstorm | Updates for Kuwait: +25 cases (now 412793), +16663 tests (now 4.9 million) since 23 hours ago | 21:40 |
| Brainstorm | New from COVID tweets: Brian Hjelle, virologist (@hjelle_brian): If one believes that preprint out of IA, (I do!) white tail deer are an extremely competent host for SARS2. Both viral RNA and antibodies are common as dirt in wild, captive animals. → https://twitter.com/hjelle_brian/status/1456723130697719810 | 21:50 |
| Brainstorm | New from COVID tweets: Brian Hjelle, virologist (@hjelle_brian): Unstated truth about each SARS2 antiviral: they're each a foot in the door toward ever more effective versions- and clever combinations thereof. Ask our old fiends HIV, HCV. → https://twitter.com/hjelle_brian/status/1456725695078416385 | 22:00 |
| Brainstorm | Updates for Germany: +28678 cases (now 4.7 million), +134 deaths (now 96897) since 22 hours ago — Maldives: +130 cases (now 88516), +2801 tests (now 1.6 million) since 6 hours ago | 22:05 |
| Brainstorm | New from COVID tweets: Marc Veldhoen (@Marc_Veld): Lipid nanoparticles enhance the efficacy of mRNA and protein subunit vaccines by inducing robust T follicular helper cell and humoral responsesLNPs are immunestimulatory, independent of MyD88 or MAVS, but depending on IL-6, to generate Tfh cells.cell.com/immunity/fullt… → https://twitter.com/Marc_Veld/status/1456730055837732865 | 22:11 |
| Brainstorm | New from COVID tweets: Michael Lin, PhD-MD 🧬 (@michaelzlin): But I can reveal a few things about how Paxlovid works and why it works so well. I can also tell you some info about how such drugs are designed, which it seems Pfizer will not reveal. But first, for reference, here's Pfizer's releasepfizer.com/news/press-rel… → https://twitter.com/michaelzlin/status/1456734281011634177 | 22:31 |
| Brainstorm | Updates for Mali: +61 cases (now 16294), +1 deaths (now 571), +1347 tests (now 460292) since 23 hours ago — Bahrain: +28 cases (now 277011), +16029 tests (now 7.0 million) since a day ago — Djibouti: +2 cases (now 13491), +899 tests (now 238396) since a day ago | 23:07 |
| Brainstorm | Updates for India: +10333 cases (now 34.3 million), +393 deaths (now 460268) since 15 hours ago — Greenland: +13 cases (now 859), +575 tests (now 90235) since a day ago | 23:32 |
| Brainstorm | New from r/WorldNews: worldnews: British Columbia to permanently close all mink farms over COVID-19 transmission risk → https://old.reddit.com/r/worldnews/comments/qnlyqs/british_columbia_to_permanently_close_all_mink/ | 23:34 |
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