| LjL | teaches me not to use random nitter instances ;( it's in the site title here https://twitter.censors.us/ | 00:00 |
|---|---|---|
| LjL | time to remove that one | 00:00 |
| LjL | sigh | 00:00 |
| LjL | %title https://twitter.com/jburnmurdoch/status/1466136354308476939 | 00:01 |
| LjL | %title https://twitter.com/jburnmurdoch/status/1466136354308476939 | 00:02 |
| Brainstorm | LjL: From twitter.com: John Burn-Murdoch (@jburnmurdoch): "NEW: updated chart showing today’s numbers from Gauteng in South Africa: • Now with test positivity, for those who have asked whether this is driven by increased testing • And stating in the title that hospital admissions are a lagging indicator, as many have requested" | nitter | 00:02 |
| LjL | that's better | 00:02 |
| LjL | anyway, that's not good news, although the hospitalization part might be... but as he notes, it's a lagging indicator | 00:03 |
| xx | that's just the bot adding the title of the page after the | separator | 00:03 |
| LjL | xx, yeah, but i don't want a title like that, and the actual website is twitter.com, the bot just turns it into a nitter instance because twitter.com isn't kind enough to actually provide a <title>, which is all well and good until the actual title starts being hella weird | 00:09 |
| Brainstorm | New from COVID on Twitter: Michael Lin, PhD-MD 🧬 (@michaelzlin): People are still asking questions that are answered in the chart, so I added more explicit labels to each cell in the chart.A "Pfizer vaccine" is two doses. So if you're wondering what happens after 3 doses for example, look up Pfizer primary and [... want %more?] → https://twitter.com/michaelzlin/status/1466543929935818761 | 00:10 |
| LjL | eh but they're neutralization titers to the D614G spike | 00:13 |
| LjL | can we like, get them for variants that are actually somewhat relevant *now*? ;( | 00:13 |
| LjL | well it says in the thread that 400 of the circled unit is what's expected to be necessary for 90% efficacy against Delta | 00:18 |
| LjL | and that Omicron will possibly need more | 00:18 |
| LjL | so with 3 Pfizers (what i'm going to get), i'll barely be good for Delta | 00:19 |
| LjL | </negative> | 00:19 |
| LjL | too bad all these american data don't include AZ | 00:20 |
| dTal | s/these/this | 00:24 |
| dTal | (and also I suppose s/don't/doesn't) | 00:24 |
| LjL | Sorry, can't comment, am busy sticking pins in a dTal-shaped voodoo doll | 00:32 |
| Brainstorm | Updates for Netherlands: +23125 cases (now 2.7 million) since 23 hours ago | 00:33 |
| Brainstorm | New from Contagion Live: Six Different COVID-19 Boosters Effective for AstraZeneca or Pfizer-BioNTech Recipients: A study released tonight found 6 COVID-19 booster shots increased immunity for individuals who received a full 2 doses of the AstraZeneca [... want %more?] → https://www.contagionlive.com/view/six-different-covid-19-boosters-effective-for-astrazeneca-or-pfizer-biontech-recipients | 00:38 |
| joerg | >>pressure on hospitals is lower at this time compared to same time last year<< I can't confirm this for Germany, not at all | 00:43 |
| joerg | >>Pfizer's line is that the current vaccine will probably work<< nevertheless they stated they already are about to develop an adapted vaccine version just in case it's needed, and it takes a 100 days. No? | 00:47 |
| joerg | and indeed, Paxlovid is very good news | 00:48 |
| Brainstorm | New from COVID on Twitter: Michael Lin, PhD-MD 🧬 (@michaelzlin): Kind of related, today the CoV-Boost trial results from the UK were finally released. Seems like ages ago when this was announced, but it was only May 19 (gov.uk/government/new…). In SARSCoV2 speed, that is eons, I guess.thelancet.com/journals/lance… → https://twitter.com/michaelzlin/status/1466567576746483713 | 01:44 |
| Brainstorm | New from COVID on Twitter: Michael Lin, PhD-MD 🧬 (@michaelzlin): Pleasantly surprised Novavax has as good T cell responses as Ad26 and Pfizer. Data on its T cell responses had been lacking.But T cell function is very age-dependent. This should give caution to those who claim T cell responses will save [... want %more?] → https://twitter.com/michaelzlin/status/1466569878060429315 | 01:54 |
| LjL | joerg, yes, "just in case", but Moderna has stated it with a different nuance. and Moderna has a track record of starting a variant vaccine ealier (they have a Beta vaccine whereas Pfizer only started a Delta vaccine) | 01:59 |
| Brainstorm | New from COVID on Twitter: Michael Lin, PhD-MD 🧬 (@michaelzlin): And here are the same boosters tested after PF+PF primary vaccination. The antibody differences are smaller but still RNA > JJ ~ AZ (ChAd) ~ NVX. T cell stimulation goes Moderna > Pfizer (BNT) ~ JJ ~ AZ > NVX pic.twitter.com/uqzSG9bTKH → https://twitter.com/michaelzlin/status/1466571339829952514 | 02:03 |
| Brainstorm | New from COVID on Twitter: Michael Lin, PhD-MD 🧬 (@michaelzlin): Also the T cell boost NVX shows here suggests those with NVX primaries should have good T cell function too. And we already know 2x NVX gives high antibodies between 2x Pfizer and 2x Moderna. That's convenient because of its stability in the fridge. → https://twitter.com/michaelzlin/status/1466575589779783682 | 02:13 |
| Brainstorm | New from COVID on Twitter: Michael Lin, PhD-MD 🧬 (@michaelzlin): Why NVX didn't boost T cells in RNA-vaxxed as well as in Ad-vaxxed is a mystery. In cellular immunology speak, that means T cells expanded by Ad vaccination are restimulated by cytokines or cell-cell interactions activated by NVX, more so than T [... want %more?] → https://twitter.com/michaelzlin/status/1466577759073759233 | 02:22 |
| LjL | ublx, https://en.wikipedia.org/wiki/PF-07321332#Misleading_comparison_with_ivermectin | 02:24 |
| LjL | people don't look very interested anyway https://trends.google.com/trends/explore?q=paxlovid | 02:25 |
| -RSSBot[LjLmatrix- Zotero / COVID links Group / Top-Level Items: Safety and immunogenicity of seven COVID-19 vaccines as a third dose (booster) following two doses of ChAdOx1 nCov-19 or BNT162b2 in the UK (COV-BOOST): a blinded, multicentre, randomised, controlled, phase 2 trial ( https://www.zotero.org/groups/covid_links/items/E77B4CSU ) | 02:25 | |
| LjL | and https://trends.google.com/trends/explore?q=paxlovid,Pfizer%20pill doesn't make it look better | 02:26 |
| LjL | we just don't thrive on good news | 02:26 |
| ublx | the conspiracy people said the same thing about Molnupiravir | 02:27 |
| LjL | well, in particular Campbell made the Pfizer-ivermectin comparison though | 02:28 |
| LjL | based on other anecdotes of which people are now following Campbell... i believe he's fully boarded the nutter train | 02:29 |
| ublx | ... | 02:29 |
| ublx | maybe campbell should take a month off | 02:29 |
| LjL | someone who definitely doesn't "believe in covid" very much linked me to a video of his about vitamin D | 02:30 |
| LjL | i didn't watch the video but he's already screaming in the description that the government isn't acting to give it to people | 02:30 |
| LjL | in fact, the NHS is the only health authority i'm aware of that *does* recommend vitamin D supplementation for all adults (regardless of COVID) | 02:31 |
| Brainstorm | New from COVID on Twitter: Michael Lin, PhD-MD 🧬 (@michaelzlin): Perhaps the Ad-expanded T cells tend to live in places that are stimulated well by subsequent NVX, better than RNA-expanded T cells. Since case and hospitalization protection seem to correlate with antibody levels, doesn't seem to matter where your [... want %more?] → https://twitter.com/michaelzlin/status/1466577760281788416 | 02:31 |
| ublx | and that advocacy seems to have worked since covid, since the shelves are often empty of vit d | 02:34 |
| LjL | ublx, i'm not necessarily against that, i think the evidence for vitamin D helping against COVID may be inconclusive, but also strongly suggestive, and since most people are lacking vitamin D *anyway* to the point the NHS recommends supplementation for everyone... i think people should take it | 02:35 |
| LjL | but you see https://www.youtube.com/watch?v=fbGug3rczx4 and the title immediately has a bad ring to it | 02:35 |
| LjL | %title | 02:35 |
| Brainstorm | LjL: From www.youtube.com: Vitamin D, government inaction - YouTube | 02:35 |
| ublx | funny. a year or so ago for a while it was almost impossible to find paracetamol in the shops. but now there's any amount of it while aspirin is hard to find | 02:37 |
| Brainstorm | New from COVID on Twitter: Eric Topol (@EricTopol): If you say all adults should get a booster, as CDC finally did, that means mRNA vaccines (and all others except J&J) = a 3-dose vaccineThe exception to 3-doses other than J&J are people w/ prior Covid—1 or 2 shots establishes potent hybrid immunity pic.twitter.com/7WE6YASyq3 → https://twitter.com/EricTopol/status/1466582253652168706 | 02:41 |
| minthos | I don't know what the official recommendations are but in Norway it's very common to take cod liver oil in the winter for vit D and omega-3 | 02:42 |
| minthos | probably officially reccommended | 02:43 |
| minthos | sunlight is great for vit D but there isn't enough of it in the winter | 02:43 |
| LjL | he talks about correlation in a kindergarten way but skips over the p > 0.05 values that he does have printed on the slide ;( | 02:44 |
| LjL | oh nevermind he does note it later | 02:44 |
| LjL | the "conclusions" he cite say the vit D level is a *predictor* of COVID mortality | 02:47 |
| LjL | but he jumps to say that paper suggests causality | 02:47 |
| LjL | because they measured vit D pre-hospital admission and, for patients who later died, it was already low | 02:48 |
| LjL | but that doesn't show causality... it just shows that causality *is not the other way around* (i.e. it's not COVID itself that lowers vit D levels) | 02:48 |
| LjL | showing causality means that you show that if you give people more vitamin D, they actually recover better, or get less sick | 02:48 |
| LjL | because the other possibility is that people who just don't get enough vit D from the sun are *also* people who don't exercise enough, etc | 02:49 |
| LjL | which means vit D may well be a predictor, but even if you pump it to over 9000 artificially with supplements, it won't make a difference to COVID death | 02:49 |
| xx | is there some final word on the ivermectin thing yet? Last I heard (maybe fake news) is that india is successfully using it and is suing the guy who claimed that it does nothing | 02:49 |
| Brainstorm | New from COVID on Twitter: Tomás Aragón, MD, DrPH (@DrTomasAragon): L.A. County Reports First Case of the Omicron Variant1 Get vaccinated or boosted2 Upgrade mask for indoors (fit/filtration matter)3 Improve ventilation (home, work, school, ...)4 Test based on risk (pre/post) or symptoms (do early)5 Stay [... want %more?] → https://twitter.com/DrTomasAragon/status/1466585594247585792 | 03:00 |
| Brainstorm | New from COVID on Twitter: Michael Lin, PhD-MD 🧬 (@michaelzlin): Thus, vs other refrigeration-compatible vaccines (AZ, J&J, Valneva, Curevac), Novavax had better Ab responses as a primary vaccine, and similar or better Ab boosting. It also boosted T cells better than Valneva and Curevac. Thus it could be the [... want %more?] → https://twitter.com/michaelzlin/status/1466589800777928710 | 03:09 |
| Brainstorm | New from The Indian Express: World: Armed man outside UN arrested after standoff, lockdown → https://indianexpress.com/article/world/united-nations-new-york-gunman-7653540/ | 03:18 |
| Brainstorm | Updates for United Kingdom: +53589 cases (now 10.4 million) since 23 hours ago | 03:33 |
| sdfgsdfg | whoa | 03:34 |
| sdfgsdfg | 55k and going up in uk ! nice | 03:34 |
| sdfgsdfg | I mean not good * | 03:34 |
| sdfgsdfg | also in south africa cases have been doubling they're around 11k and going up | 03:34 |
| xx | number of cases is hardly relevant in my opinion, that's just an aspect of number of testing. What matters is number of deaths and hospitalizations | 03:35 |
| sdfgsdfg | that was when we thought we wouldn't need boosters | 03:38 |
| sdfgsdfg | and everything would be alright | 03:39 |
| xx | someone seriously thought that? | 03:39 |
| sdfgsdfg | there was no mention of boosters | 03:40 |
| sdfgsdfg | so it's my assumption hah | 03:40 |
| sdfgsdfg | more and more vaccinated people die every day | 03:41 |
| sdfgsdfg | numbers are increasing :P | 03:41 |
| xx | well, yeah, the vaccine does not make you immortal | 03:41 |
| xx | you can still get hit by a bus even if you had 3 doses of the vaccine | 03:42 |
| xx | (or die of stroke, heart attack, ...) | 03:43 |
| Brainstorm | New from r/WorldNews: worldnews: New Covid drug that cuts death by 80% approved in UK amid fight against Omicron → https://old.reddit.com/r/worldnews/comments/r7o98s/new_covid_drug_that_cuts_death_by_80_approved_in/ | 03:56 |
| LjL | uh that's a new one | 04:22 |
| LjL | from The Sun, nonetheless | 04:22 |
| LjL | %wik sotrovimab | 04:22 |
| Brainstorm | LjL, from English Wikipedia: Sotrovimab, sold under the brand name Xevudy, is an investigational human neutralizing dual-action monoclonal antibody with activity against severe acute respiratory syndrome coronavirus 2, known as SARS-CoV-2. It is under development by GlaxoSmithKline and Vir Biotechnology, Inc. Sotrovimab is designed to [... want %more?] → https://en.wikipedia.org/wiki/Sotrovimab | 04:23 |
| LjL | it looks like it has similar efficacy to the "Pfizer pill", but it's a monoclonal antibody, not an antiviral | 04:23 |
| Brainstorm | Updates for Germany: +73185 cases (now 6.0 million) since 23 hours ago — Netherlands: +23141 cases (now 2.7 million) since 23 hours ago | 04:30 |
| -RSSBot[LjLmatrix- Zotero / COVID links Group / Top-Level Items: Coronavirus (COVID-19) Update: FDA Authorizes Additional Monoclonal Antibody for Treatment of COVID-19 ( https://www.zotero.org/groups/covid_links/items/AZEFPHU4 ) | 04:30 | |
| -RSSBot[LjLmatrix- Zotero / COVID links Group / Top-Level Items: Some experts believe Omicron variant may have evolved in an animal host ( https://www.zotero.org/groups/covid_links/items/7BJZ9M9U ) | 04:30 | |
| Brainstorm | New from Reddit (test): Covid2019: Remarks by US President on COVID-19 Winter Plan: 'we have safe, effective vaccines for children age five and older, with 20 mln children and counting now vaccinated.. pledging 200 mln more doses within next 100 days to world for 1.2 bln [... want %more?] → https://old.reddit.com/r/Covid2019/comments/r7pbhn/remarks_by_us_president_on_covid19_winter_plan_we/ | 04:43 |
| Dredd | I somehow ended up on this veiled antivaxx article: https://thinkscotland.org/2021/12/were-not-even-waiting-on-the-science-never-mind-following-it/ | 05:03 |
| Dredd | It started off trying to sound neutral then leaps into a bunch of stuff that is totally wrong | 05:04 |
| Dredd | Like objectively wrong | 05:04 |
| Dredd | But I could imagine it convincing some people who don't have the context to interpret it in | 05:04 |
| Dredd | And the author is complaining about being banned from Twitter 😂 | 05:05 |
| Dredd | <LjL> "uh that's a new one" <- Seems like everything is approved in the UK these days | 05:06 |
| Dredd | <ublx> "maybe campbell should take a..." <- I think he's cashing in on conspiracies to get those sweet YouTube bux | 05:11 |
| sdfgsdfg | an antivaxx article ! | 05:22 |
| sdfgsdfg | hahaha | 05:22 |
| sdfgsdfg | let me read that | 05:22 |
| sdfgsdfg | hmmm | 05:22 |
| sdfgsdfg | quite a lot of governments around the world do not recognize natural immunity, they ban even their naturally immune citizens from everything and force them to be vaccinated | 05:25 |
| sdfgsdfg | there are these halfassed publications comparing antibodies generated from really, really mild cases to a hardcore vaccine enthusiasts 2 shots.+ booster | 05:26 |
| sdfgsdfg | antibodies | 05:26 |
| sdfgsdfg | which makes no sense at all, science became politics | 05:26 |
| Dredd | <joerg> "Peter: we have no lockdown (..." <- Ah I see. So shops are supposed to check you for proof of vaccines and stop you coming in otherwise? | 05:27 |
| Brainstorm | Updates for Belgium: +23113 cases (now 1.8 million), +48 deaths (now 27120), +148651 tests (now 25.0 million) since 23 hours ago — India: +9216 cases (now 34.6 million), +391 deaths (now 470115) since 23 hours ago | 05:38 |
| sdfgsdfg | xx : The only person I know who was hospitalized from covid was triple vaccinated by 2 different brands | 06:05 |
| sdfgsdfg | she died | 06:05 |
| sdfgsdfg | age between 60-65 | 06:06 |
| sdfgsdfg | non-smoker | 06:06 |
| sdfgsdfg | ¯\_(ツ)_/¯ | 06:06 |
| Brainstorm | New from r/WorldNews: worldnews: Philippine Largest Public Hospital: No new COVID-19 admission in last 2 days → https://old.reddit.com/r/worldnews/comments/r7q4ki/philippine_largest_public_hospital_no_new_covid19/ | 06:17 |
| Brainstorm | New from r/WorldNews: worldnews: Covid - 19 Vaccine Now Mandatory to get Euthanized in Germany → https://old.reddit.com/r/worldnews/comments/r7rcfn/covid_19_vaccine_now_mandatory_to_get_euthanized/ | 06:36 |
| Brainstorm | Updates for Brandenburg, Germany: +4241 cases (now 186828), +21 deaths (now 4183) since a day ago — Saxony-Anhalt, Germany: +3811 cases (now 166266), +11 deaths (now 3835) since a day ago — Mecklenburg-Vorpommern, Germany: +1633 cases (now 75321), +4 deaths (now 1341) since a day ago — Germany: +73277 cases (now 6.1 million) since 20 hours ago | 06:40 |
| Brainstorm | New from r/WorldNews: worldnews: Marathon lockdown ends in Auckland, New Zealand with reopening of nightclubs, cafes and casinos → https://old.reddit.com/r/worldnews/comments/r7ryco/marathon_lockdown_ends_in_auckland_new_zealand/ | 07:13 |
| Brainstorm | Updates for United Kingdom: +53605 cases (now 10.4 million), +143 deaths (now 145729) since 14 hours ago | 07:30 |
| Brainstorm | New from The Indian Express: World: Covid-19: New York confirms at least 5 omicron cases → https://indianexpress.com/article/world/new-york-covid-19-omicron-variant-cases-7653761/ | 07:32 |
| Brainstorm | New from Reddit (test): CoronaVirus_2019_nCoV: SARS-CoV-2 evolution in animals could provide insights on the mutability of COVID-19: When animals catch COVID-19 from humans, new SARS-CoV-2 variants can arise. → https://old.reddit.com/r/CoronaVirus_2019_nCoV/comments/r7ssz6/sarscov2_evolution_in_animals_could_provide/ | 07:51 |
| Brainstorm | New from MedicineNet: (news): Survivors of Severe COVID Face Doubled Risk for Death a Year Later → http://www.medicinenet.com/script/main/art.asp | 08:00 |
| Brainstorm | New from COVID on Twitter: Covid Fact Check UK (@fact_covid): “Overall, the mRNA vaccines gave the best boost to antibodies and T-cells, which are known to be important factors in how well vaccines work, particularly after two initial doses of AZ.“The vaccines were equally effective in the over-70s and [... want %more?] → https://twitter.com/fact_covid/status/1466669010225881091 | 08:28 |
| Brainstorm | New from COVID on Twitter: Covid Fact Check UK (@fact_covid): Hopefully this will translate into protection against Omicron too, at least from hospitalisation and death. Only time will tell but one thing is clear - a third dose gives a *huge* boost to your immunity, whatever vaccine you had first, so please get one [... want %more?] → https://twitter.com/fact_covid/status/1466669012545413124 | 08:38 |
| Brainstorm | New from r/Coronavirus: Daily Discussion Thread | December 03, 2021: Please refer to our Wiki for more information on COVID-19 and our sub. You can find answers to frequently asked questions in our FAQ , where there is valuable information such as our: → https://old.reddit.com/r/Coronavirus/comments/r7tzxr/daily_discussion_thread_december_03_2021/ | 09:06 |
| Dredd | <sdfgsdfg> "xx : The only person I know..." <- Are you implying the vaccines didn't help or worse, that they caused her death? | 09:09 |
| xx | let me check backlog to see what I meant there | 09:09 |
| xx | where was that? | 09:11 |
| xx | I don't know where that was, but I can definitely answer that I don't know anyone who'd die as a result of the vaccine, though I'm sure someone somewhere probably did just due to statistics | 09:11 |
| Dredd | I'm responding to sdfgsdfg who responded to you, sorry for the confusion | 09:12 |
| xx | ah | 09:12 |
| Brainstorm | Updates for Germany: +73279 cases (now 6.1 million) since 23 hours ago | 09:34 |
| Brainstorm | New from COVID on Twitter: Marc Veldhoen (@Marc_Veld): Safety and immunogenicity of seven COVID-19 vaccines as a third dose (booster) following two doses of ChAdOx1 nCov-19 or BNT162b2 in the UK (COV-BOOST): a blinded, multicentre, randomised, controlled, phase 2 trial thelancet.com/journals/lance… → https://twitter.com/Marc_Veld/status/1466689293972385795 | 09:44 |
| Dredd | I'm in a Starbucks and like 90% of people have masks on again | 10:21 |
| Dredd | A while back it dropped to 0 | 10:21 |
| CoJaBo | Dredd: I saw one mask (other than the pharmacist) when I went to get my booster last weekend | 10:29 |
| Brainstorm | Updates for France: +2 deaths (now 120313) since 12 hours ago | 10:37 |
| joerg | Dredd: >>So shops are supposed to check you for proof of vaccines and stop you coming in otherwise?<< exactly | 10:40 |
| Dredd | Oh that reminds me, I need to go to a pharmacy some time to try and get a walk in flu jab appointment | 10:40 |
| CoJaBo | I'm still debating whether or not to get a flushot | 10:40 |
| Dredd | joerg: that wouldn't work in the UK. Even the idea of checking someones papers sets off UK people | 10:40 |
| Dredd | And shops are refusing to enforce the mask mandate here | 10:41 |
| joerg | Dredd: even the fines are already defined, and they are rather steep (iirc 2500€) | 10:41 |
| Dredd | Even though it's law | 10:41 |
| Dredd | So there's no way they would confront people for vaccines | 10:41 |
| Dredd | Who enforces the fine? The supermarkets would just not report anything here | 10:41 |
| joerg | the 2k5 fine is for shop owners not checking | 10:42 |
| Dredd | Lol, UK people have raged at the idea of vaccination being mandatory for frontline health workers even | 10:42 |
| Dredd | How will they know? | 10:42 |
| CoJaBo | Lol, around here it's more common to find shops that ban vaccinated people from entering | 10:42 |
| Dredd | Also 2.5k for a national supermarket might just be worth paying | 10:42 |
| spacehunter4[m] | Hi - new here. Where can i get a non real but working covid-cert? | 10:43 |
| joerg | there are thems of $authorities checking in civil if the rules are obeyed | 10:43 |
| joerg | teams | 10:43 |
| Dredd | spacehunter4[m]: A vaccination thing? | 10:43 |
| spacehunter4[m] | Dredd: Yes with QR-Code | 10:43 |
| Dredd | Go get vaccinated | 10:44 |
| Dredd | 😛 | 10:44 |
| spacehunter4[m] | Dredd: No | 10:44 |
| Dredd | Why not? | 10:44 |
| spacehunter4[m] | Dredd: Unsecure | 10:44 |
| Dredd | How so? | 10:44 |
| joerg | >>might just be worth paying<< I'm sure there are escalations for repetitive violations | 10:44 |
| CoJaBo | yours have QR codes? | 10:44 |
| Dredd | joerg: I still think it wouldn't work here 😀 | 10:45 |
| joerg | quite possible | 10:45 |
| spacehunter4[m] | Sorry my english is to bad to explain | 10:46 |
| Dredd | Given we have protests shutting down vaccination centers lol | 10:46 |
| joerg | spacehunter4[m]: vaccination is safe, get your info here and then get your jab. There's no fake QR for you or anybody | 10:46 |
| Dredd | spacehunter4: no worries, you have the right to not get vaccinated but if you choose that you are also choosing to live with the restrictions that come with it | 10:46 |
| Dredd | They are there for a reason | 10:46 |
| joerg | what Dredd said | 10:47 |
| Dredd | You won't find help getting false certs here as joerg said 🙂 | 10:47 |
| spacehunter4[m] | ok ack | 10:49 |
| Dredd | This room is largely pro-vaccine / trust in the science / covid is real | 10:50 |
| joerg | spacehunter4[m]: find a non-AfD medical doctor, get advice and education there about any concerns you have with vaccination. Please understand you're acting antisocial and criminal in several very real aspects when you try to pretend you were not vulnerable and infectious and you risk the health and life of others doing so | 10:50 |
| Dredd | AfD? | 10:51 |
| joerg | a far right political party | 10:51 |
| joerg | antivax, anti-covidmeasure | 10:51 |
| Brainstorm | New from BMJ: (news): Effectiveness of public health measures in reducing the incidence of covid-19, SARS-CoV-2 transmission, and covid-19 mortality: systematic review and meta-analysis → http://www.bmj.com/content/375/bmj.n2997.short | 10:51 |
| joerg | our beloved neonazis | 10:52 |
| Dredd | I see, the UK version was called the BNP (actually there were several other ones too 😟) and then somewhat more civilised but isolationist was UKIP | 10:53 |
| Dredd | BNP = British Nationalist Party iirc | 10:54 |
| Dredd | There was also the English Defence League I think | 10:54 |
| rpifan | https://www.youtube.com/watch?v=Lyy39zq3mHA | 11:07 |
| rpifan | hm thats really not good news | 11:07 |
| rpifan | apparently they will make us get boosters every year | 11:07 |
| joerg | 12 months (like flu) sounds reasonable, yes. I prefer that over lockdown and death from covid, heck even over long covid | 11:09 |
| joerg | and once we "are done vaccinating everybody" you are free to get your annual refresh by catching the rona as well | 11:10 |
| joerg | like we got with flu | 11:10 |
| joerg | right now we got the problem that even in "good" countries we have a nn% of completely corona-naive population and we know they ALL will catch the virus and out of 100, maybe 2 or 5 will get a severe course and end in hospital and ICU | 11:15 |
| joerg | once nobody is corona-naive anymore, that will end, no matter if you vaccinate everybody every year or not | 11:16 |
| joerg | compare for flu | 11:17 |
| joerg | *here* corona actually is just another flu | 11:17 |
| rpifan | yea | 11:21 |
| rpifan | but im already genesen | 11:21 |
| rpifan | why do i need to get a vaccine | 11:21 |
| joerg | and let me add: we got districts in germany with almost 2000/100k7d - plain math tells that those districts will be done with corina in 50 weeks the latest | 11:21 |
| rpifan | its really annoying | 11:21 |
| joerg | corona too | 11:21 |
| joerg | rpifan: because if you're not, you occupy the ICU bed I need for my cancer OP | 11:22 |
| joerg | and I have to pay for your idiocy | 11:22 |
| joerg | not only in money but also in lockdown I suffer, and in my own health and lifetime | 11:22 |
| joerg | no mercy | 11:23 |
| rpifan | thats not really true | 11:23 |
| joerg | that IS true | 11:23 |
| rpifan | ive already had covid | 11:23 |
| joerg | meh! | 11:23 |
| joerg | fool | 11:23 |
| joerg | then you are immunized already | 11:23 |
| joerg | just not very well | 11:24 |
| rpifan | but we cant just force ppl to get vaciinated year after year | 11:24 |
| joerg | strongly recommended to get a second and third immunization pass | 11:25 |
| joerg | rpifan: after 3 jabs, immunization is considered "finished" and - as I just elaborated - we are not short on ICU beds anymore when everybody is | 11:25 |
| joerg | I *strongly* oppose any live long recurring mandatory vaccination | 11:27 |
| joerg | not needed | 11:27 |
| joerg | rpifan: after 3rd pass (booster) you probably are protected from severe course for several years, and you will catch mild covid every other year and so refresh your immune protection without occupying an ICU bed | 11:29 |
| rpifan | im not convinced | 11:30 |
| rpifan | we had started out with 2 | 11:30 |
| rpifan | and now 3? | 11:30 |
| rpifan | and then 4 | 11:30 |
| joerg | *shrug* what can I say to convice you? Actually of _what_? | 11:30 |
| Brainstorm | New from The Indian Express (Health): Health: Omicron in India: How to deal with anxiety over the new Covid-19 variant → https://indianexpress.com/article/lifestyle/health/omicron-india-cases-covid-19-new-variant-anxiety-fear-mental-health-7653714/ | 11:30 |
| joerg | look buddy, this is a new vaccine, nobody knows how it performs long term. What we know though is how endemic infections work | 11:31 |
| rpifan | once you get me the novavax id be more willing to ge it | 11:32 |
| rpifan | get | 11:32 |
| darsie | Has there been herd immunity somewhere? | 11:33 |
| joerg | we didn't know 2 jabs were not a complete vaccination cycle. We learnd that recently, it's a 3 pass regimen obviously. After 3 passes you got a protection against severe course for several years since even with 2 you get a protection of more than one year. And if we had a 100% vaccinated with 2 jabs now, we wouldn't _need_ a booster. It would still be wise but not mandatory | 11:34 |
| joerg | re novavax: there **never** been a vaccine controlled, evaluated and tested more thoroughly than the ones already available and in use. NEVER, for ANY disease, not even same league | 11:40 |
| joerg | the age old flu vaccination never been same magnitude of safety | 11:40 |
| joerg | 9 months ago you could argue "I'm not convinced yet, I want to see how it pans out". Now there are BILLIONS of months of tight observation for any adverse effects and the vaccines *are* safe | 11:43 |
| joerg | we should mix the vaccine with Jaegermeister and hand it out at discount price on parties, I guess ;-P | 11:48 |
| joerg | you say you don't know what's in the vaccine? do you know what's in Jaegermeister? or in Coca Cola? For the vaccine you _could_ know if you only looked it up | 11:49 |
| Brainstorm | New from BMJ: Covid-19: Build on success of vaccination programme in reaching ethnic minority groups, report recommends: Lessons learnt in relation to increasing uptake of the covid-19 vaccine among ethnic minority groups should now be applied to the booster programme, a government progress report recommends.1This... → http://www.bmj.com/content/375/bmj.n3003.short | 11:58 |
| worldsaviorcyber | Master Money Using To Fully Control Your Life - This book will become legendary book that will save this civilization from total collapse and destruction. | 12:04 |
| worldsaviorcyber | Full info at https://eternalsacredbooks.wordpress.com/2021/12/03/master-money-using-to-fully-control-your-life/ | 12:04 |
| joerg | could somebody please goetrack that IP 2001:470:69fc:105::1:4549 and place an EMP bomb there? | 12:11 |
| joerg | geo* | 12:11 |
| joerg | LjL: sacredebooks, thelordonline, truesaviorcyber, worldsaviorcyber, messiahbooks, eternalbooks, I detect a pattern. >:-( maybe ban *lord*, *savior*, *books* ? | 12:16 |
| darsie | https://www.iplocation.net/ip-lookup | 12:17 |
| joerg | alas, changing IP frequently | 12:18 |
| darsie | Zapping computers of ppl who are part of botnets ... | 12:19 |
| joerg | *nod* | 12:20 |
| joerg | http://reisenweber.net/irclogs/libera/__covid-19/search?q=sacredebooks%7Cthelordonline%7Ctruesaviorcyber%7Cworldsaviorcyber%7Cmessiahbooks%7Ceternalbooks | 12:22 |
| Brainstorm | Updates for Nepal: +223 cases (now 822172), +6400 tests (now 4.6 million) since a day ago | 12:35 |
| Brainstorm | New from ECDC: Communicable disease threats report, 28 November-4 December 2021, week 48: This issue of the CDTR covers the period 28 November-4 December 2021 and includes updates on COVID-19, Ebola, and Influenza. → https://www.ecdc.europa.eu/en/publications-data/communicable-disease-threats-report-28-november-4-december-2021-week-48 | 12:55 |
| Brainstorm | New from ECDC: Data on the daily number of new reported COVID-19 cases and deaths by EU/EEA country: The downloadable data file is updated daily and contains the latest available public data on COVID-19. Each row/entry contains the number of new cases and deaths reported per day and [... want %more?] → https://www.ecdc.europa.eu/en/publications-data/data-daily-new-cases-covid-19-eueea-country | 13:05 |
| Brainstorm | New from The Indian Express: World: WHO says vaccination, not travel curbs, key to battling Omicron → https://indianexpress.com/article/world/who-says-vaccination-not-travel-curbs-key-to-battling-omicron-7654634/ | 13:23 |
| Brainstorm | New from Reddit (test): CoronaVirus_2019_nCoV: Rancho Cordova couple loses son to COVID-19, warns other parents → https://old.reddit.com/r/CoronaVirus_2019_nCoV/comments/r7y32p/rancho_cordova_couple_loses_son_to_covid19_warns/ | 14:19 |
| Brainstorm | Updates for Germany: +73095 cases (now 6.1 million), +1966027 tests (now 85.8 million) since 22 hours ago | 14:39 |
| Brainstorm | New from BBC Health: Covid: First data points to Omicron re-infection risk: Scientists in South Africa have identified a spike in the numbers catching Covid again. → https://www.bbc.co.uk/news/health-59520945 | 14:48 |
| Brainstorm | New from WHO Euro: Greece: civil society reduces barriers to health and education for young people with disabilities during the pandemic: Together for Children, a network of Greek civil society [... want %more?] → {"param":"apiKey","title":"Invalid authorization","type":"INVALID_AUTHORIZATION","status":401,"detail":"Expected authentication to be provided in \"apiKey\" query param"} | 14:57 |
| Brainstorm | Updates for Switzerland: +5055 cases (now 1.0 million) since 23 hours ago | 15:04 |
| Brainstorm | New from COVID on Twitter: Eric Topol (@EricTopol): Omicron's doubling time in Gauteng exceeds the prior variants of concern, but the question as to whether in can displace Delta as the dominant variant there and globally looms thelancet.com/journals/lance… @TheLancet pic.twitter.com/7Y4JQ2BFLh → https://twitter.com/EricTopol/status/1466770233952067584 | 15:07 |
| Brainstorm | New from COVID on Twitter: Eric Topol (@EricTopol): Review by @ECDC_EU suggests Omicron could become the dominant version in Europe in the next few months and calls for aggressive action, especially with vaccinationecdc.europa.eu/sites/default/… pic.twitter.com/BB9bCJcTjL → https://twitter.com/EricTopol/status/1466772463165927426 | 15:16 |
| Brainstorm | New from COVID on Twitter: Eric Topol (@EricTopol): Correction in 1st post: Omicron's doubling time is less than prior variants of concern (i.e. doubling rate exceeds). Thanks @paulg for noting → https://twitter.com/EricTopol/status/1466774104334209028 | 15:26 |
| Brainstorm | New from COVID on Twitter: Marc Veldhoen (@Marc_Veld): Interim evaluation ECDC for vaccinating 5-11-year-olds.ecdc.europa.eu/en/publication… → https://twitter.com/Marc_Veld/status/1466775941896622087 | 15:35 |
| de-facto[m] | .title https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(21)02758-6/fulltext | 15:36 |
| Brainstorm | de-facto[m]: From www.thelancet.com: Omicron SARS-CoV-2 variant: a new chapter in the COVID-19 pandemic - The Lancet | 15:36 |
| joerg | >>The study, which has not been formally reviewed by other scientists, estimates Omicron could be twice as likely to cause a re-infection than earlier variants.<< from "New from BBC Health: Covid: First data points..." ^^^ | 15:38 |
| joerg | that's not as terrible as I been concerned it might be | 15:39 |
| Brainstorm | New from EMA: What's new: Medicine: Veterinary medicines European public assessment report (EPAR): Suvaxyn CSF Marker, classical swine fever vaccine (live recombinant), Date of authorisation: 10/02/2015, Revision: 4, Status: Authorised → https://www.ema.europa.eu/en/medicines/veterinary/EPAR/suvaxyn-csf-marker | 15:45 |
| de-facto | joerg, unless the protection from reinfection was around 50% in first place | 15:48 |
| joerg | :nod: | 15:48 |
| joerg | de-facto: from the lancet article you linked: >>There is no reason to believe that current COVID-19 treatment protocols and therapeutics would no longer be effective, with the possible exception of monoclonal antibodies, for which data on the omicron variant's susceptibility are not yet available<< I disagree here, we seen reports that state MAB work on omicron, no? | 15:52 |
| de-facto | well since an advantage from mAbs treatments are that they are very specific, hence only affect and target the virus itself (with minimal side effects) its also a disadvantage in this case because being specific to some characteristic surface of the virus means if that surface changed it could avoid binding to a certain degree | 15:54 |
| de-facto | meaning it depends on the mAb in question: does it bind to a conserved or mutated surface? | 15:55 |
| joerg | >>New from COVID on Twitter: Eric Topol (@EricTopol): Good to see the @Vir_Biotech/ @GSK monoclonal antibody (Sotrovimab) retains activity vs Omicron mutations in lab testsbiorxiv.org/content/10.110… → https://twitter.com/EricTopol/status/1466417111740436490<< | 15:55 |
| Brainstorm | New from COVID on Twitter: Marc Veldhoen (@Marc_Veld): If Omicron can successfully compete (unknown as yet): "If this is the case, mathematical modeling indicates that the Omicron VOC is expected to cause over half of all SARS-CoV-2 infections in the EU/EEA within the next few months." → https://twitter.com/Marc_Veld/status/1466781749376167942 | 15:55 |
| de-facto | some will be evaded, others not, so it really depends on which particular mAb we would talk about | 15:55 |
| joerg | yeah, ok. Maybe I'm nitpicking | 15:56 |
| joerg | anyway >>...for which data on the omicron variant's susceptibility are not yet available<< seems incorrect | 15:57 |
| de-facto | if you are interested in details i would recommend to follow https://twitter.com/jbloom_lab/ | 15:57 |
| de-facto | they created a website about "Sites in SARS-CoV-2 RBD where mutations reduce binding by antibodies / sera" https://jbloomlab.github.io/SARS2_RBD_Ab_escape_maps/ | 15:58 |
| de-facto | .title | 15:58 |
| Brainstorm | de-facto: From jbloomlab.github.io: Overview | Sites in SARS-CoV-2 RBD where mutations reduce binding by antibodies / sera | 15:58 |
| joerg | nah, just noted this while reading the lancet article. Thanks anyway | 15:58 |
| joerg | well, http://reisenweber.net/irclogs/libera/__covid-19/__covid-19.2021-12-02.log.html#t2021-12-02T15:46:04 was just yesterday, while the lancet article "Published:December 03, 2021", so written probably also yesterday or even earlier | 16:01 |
| joerg | can't blame them for not yet taking the new publications into account | 16:03 |
| Brainstorm | New from COVID on Twitter: Eric Topol (@EricTopol): If there's 1 thing we know about Omicron, it's this: the capability of evading our immune response. People with prior Covid who have not been vaccinated will be quite vulnerable pic.twitter.com/MSYOHItnns → https://twitter.com/EricTopol/status/1466784818041999363 | 16:05 |
| de-facto | afaik the two mAb treatments in use in Germany and EU are https://www.ema.europa.eu/en/medicines/human/EPAR/ronapreve (casirivimab / imdevimab) and https://www.ema.europa.eu/en/medicines/human/EPAR/regkirona (regdanvimab) | 16:05 |
| de-facto | according to https://www.ema.europa.eu/en/human-regulatory/overview/public-health-threats/coronavirus-disease-covid-19/treatments-vaccines/covid-19-treatments | 16:06 |
| Brainstorm | New from EMA: What's new: Document: Lagevrio (also known as molnupiravir or MK 4482) - COVID-19 - Article-5(3) procedure: Assessment report → https://www.ema.europa.eu/documents/referral/lagevrio-also-known-molnupiravir-mk-4482-covid-19-article-53-procedure-assessment-report_en.pdf | 16:25 |
| Brainstorm | Updates for Canada: +3311 cases (now 1.8 million), +20 deaths (now 29793) since 23 hours ago | 16:31 |
| de-facto | .title https://www.bundesregierung.de/breg-de/themen/coronavirus/corona-diese-regeln-und-einschraenkung-gelten-1734724 | 16:33 |
| Brainstorm | de-facto: From www.bundesregierung.de: Corona: Das sind die geltenden Regeln und Einschränkungen - Bundesregierung | 16:33 |
| de-facto | .title https://www.bundesregierung.de/resource/blob/974430/1986142/5873aa09c3896444d247b356b5df4315/2021-12-02-mpk-bund-laender-data.pdf?download=1 | 16:35 |
| Brainstorm | de-facto: From www.bundesregierung.de: Videoschaltkonferenz der Bundeskanzlerin mit den Regierungschefinnen und Regierungschefs der Länder | 16:35 |
| joerg | thanks! :-) | 16:51 |
| joerg | let's hope they get implemented and enforced now | 16:52 |
| Brainstorm | New from EMA: News and press releases: (news): ICMRA and WHO map out flexibilities used by regulators to respond to the COVID-19 pandemic, , 03/12/2021 → https://www.ema.europa.eu/en/news/icmra-who-map-out-flexibilities-used-regulators-respond-covid-19-pandemic | 16:54 |
| de-facto | btw joerg it almost looks like we are about to pass Rt~1 in Germany | 16:55 |
| joerg | yes, since a few days | 16:55 |
| joerg | we'd need 0.7 though | 16:56 |
| de-facto | yet i am not sure if its real or due to labs not being able to process enough tests | 16:56 |
| joerg | I think it's real | 16:56 |
| de-facto | holy crap ~20% of tests are positive | 16:59 |
| de-facto | one of five | 16:59 |
| de-facto | .title https://www.rki.de/DE/Content/InfAZ/N/Neuartiges_Coronavirus/Testzahl.html | 16:59 |
| Brainstorm | de-facto: From www.rki.de: RKI - Coronavirus SARS-CoV-2 - Erfassung der SARS-CoV-2-Testzahlen in Deutschland | 16:59 |
| joerg | anyway no excuse for feeling fine now, we managed to stop the acceleration, we're still cruising along with a ~57k/d new cases, we need to brake now to decelerate | 16:59 |
| de-facto | i am really not sure if we managed to stop the acceleration since positivity rate of tests went up simultaneously | 17:01 |
| de-facto | maybe a little bit, but by far not enough to regain control | 17:02 |
| Brainstorm | New from COVID on Twitter: Eric Topol (@EricTopol): In a cohort of > 200 healthy people who got 2 doses of mRNA vaccines, 25% were poor responders for neutralizing antibodies (nAbs), but had an average 20-fold increase, potent nAb response to the 3rd dosemedrxiv.org/content/10.110… pic.twitter.com/gdA9oubMhL → https://twitter.com/EricTopol/status/1466799350990839810 | 17:03 |
| joerg | wow ^^^ | 17:09 |
| de-facto | .title https://www.medrxiv.org/content/10.1101/2021.11.30.21266716v1 | 17:10 |
| Brainstorm | de-facto: From www.medrxiv.org: Third COVID-19 Vaccine Dose Boosts Neutralising Antibodies in Poor Responders | medRxiv | 17:10 |
| Brainstorm | New from ClinicalTrials.gov: (news): A Phase I/II Clinical Trial in Healthy People Aged 18 Years and Above → https://clinicaltrials.gov/ct2/show/NCT05144139 | 17:13 |
| joerg | >>25% were poor responders<< :-o | 17:15 |
| Brainstorm | New from ClinicalTrials.gov: (news): Insight Into the UAE Experience With Monoclonal Antibodies (Sotrovimab ) → https://clinicaltrials.gov/ct2/show/NCT05144178 | 17:23 |
| Brainstorm | New from ClinicalTrials.gov: (news): Cognitive, Emotional and Behavioural Impairments in Patients After Sars-Cov2 Infection → https://clinicaltrials.gov/ct2/show/NCT05143320 | 17:33 |
| Brainstorm | Updates for Netherlands: +21570 cases (now 2.7 million), +62 deaths (now 20036) since 17 hours ago — United Kingdom: +554 cases (now 10.4 million), +3 deaths (now 145730) since 22 hours ago | 17:40 |
| Brainstorm | New from ClinicalTrials.gov: (news): Cognitive Assessment in COVID Positive Patients Using the DANA App → https://clinicaltrials.gov/ct2/show/NCT05143333 | 17:42 |
| aann | BREAKING: U.S. reports 139,424 new coronavirus cases, the biggest one-day increase since September | 17:44 |
| de-facto | damn | 17:51 |
| Dredd | Have to see if it's a new trend | 18:04 |
| Brainstorm | New from Reddit (test): China_Flu: Where did ‘weird’ Omicron come from? | Science → https://old.reddit.com/r/China_Flu/comments/r83xuv/where_did_weird_omicron_come_from_science/ | 18:21 |
| Brainstorm | New from COVID on Twitter: Tulio de Oliveira (@Tuliodna): Two weeks ago we were in 200-300 cases a day, a week ago in the 1000s and now > 15,000. In addition 1 of 4 tests are positive in South Africa. Amazing increasing of #OmicronVarient twitter.com/nicd_sa/status… → https://twitter.com/Tuliodna/status/1466820922141298693 | 18:30 |
| de-facto | .title https://www.science.org/content/article/where-did-weird-omicron-come | 18:33 |
| Brainstorm | de-facto: From www.science.org: Where did ‘weird’ Omicron come from? | Science | AAAS | 18:33 |
| de-facto | .title https://www.youtube.com/watch?v=0tCRbV9mw-o | 18:36 |
| Brainstorm | de-facto: From www.youtube.com: PK zur Corona-Lage mit Spahn und Wieler | Bundespressekonferenz - YouTube | 18:36 |
| Brainstorm | New from Reddit (test): Covid2019: Large International Study Reveals Spectrum of COVID-19 Brain Complications → https://old.reddit.com/r/Covid2019/comments/r84c8a/large_international_study_reveals_spectrum_of/ | 18:40 |
| Brainstorm | New from COVID on Twitter: Eric Topol (@EricTopol): Instructive: How Delta affects macaques at 1 year after mRNA vaccinationnew @CellCellPress cell.com/cell/fulltext/… "These concerns highlight the importance of boosting for sustaining high level protection against severe disease and limiting mild infection and [... want %more?] → https://twitter.com/EricTopol/status/1466824073602691077 | 18:50 |
| Brainstorm | New from COVID on Twitter: Jeffrey Barrett (@jcbarret): So my main take-away is that growth looks fast in a country with immunity mostly from vaccines, rather than previous infection (and with a big ongoing Delta wave). We'll know a lot more soon, but this is not reassuring. → https://twitter.com/jcbarret/status/1466827276444704770 | 18:59 |
| Dredd | Tweets above unrolled: https://threadreaderapp.com/thread/1466827253824864263.html | 19:05 |
| Brainstorm | Updates for Italy: +17015 cases (now 5.1 million), +74 deaths (now 134077), +588445 tests (now 121.2 million) since a day ago | 19:07 |
| Brainstorm | New from COVID on Twitter: Eric Topol (@EricTopol): It took a year for #Omicron, the 5th variant of concern, to be detected after Gamma and Delta, picked up in late 2020 pic.twitter.com/FfWo0wZr1I → https://twitter.com/EricTopol/status/1466829397931950083 | 19:09 |
| Brainstorm | Updates for Bangladesh: +243 cases (now 1.6 million), +3 deaths (now 27989), +17387 tests (now 10.9 million) since 19 hours ago | 19:32 |
| Brainstorm | New from Contagion Live: Care Experiences and Infant Vaccination Hesitancy: A new study looked at COVID-19 related stressors and healthcare experiences, like facing discrimination, fear of perinatal infection, birth preparedness stress, telehealth prenatal care, disruptions to prenatal [... want %more?] → https://www.contagionlive.com/view/care-experiences-and-infant-vaccination-hesitancy | 19:47 |
| Brainstorm | New from CDC (old): Frequently Asked Questions about COVID-19 Vaccination: Answers to commonly asked questions about COVID-19 vaccines, including vaccine cost, availability, and types. → https://tools.cdc.gov/api/embed/downloader/download.asp | 19:57 |
| LjL | joerg, worldsaviorcyber was a Matrix user, geotracking the IP would just bring you to the Matrix gateway range | 19:58 |
| aann | https://newrepublic.com/article/162000/bill-gates-impeded-global-access-covid-vaccines | 19:59 |
| Brainstorm | Updates for United Kingdom: +703 cases (now 10.4 million), +4 deaths (now 145731) since 22 hours ago — Canada: +3269 cases (now 1.8 million) since 23 hours ago — France: +13 cases (now 7.9 million) since 22 hours ago | 20:34 |
| Brainstorm | New from FDA Press Releases: FDA Expands Authorization of Two Monoclonal Antibodies for Treatment and Post-Exposure Prevention of COVID-19 to Younger Pediatric Patients, Including Newborns: FDA revised the EUA of [... want %more?] → http://www.fda.gov/news-events/press-announcements/fda-expands-authorization-two-monoclonal-antibodies-treatment-and-post-exposure-prevention-covid-19 | 20:35 |
| LjL | you will be glad to know, if the code isn't buggy, i have finally made it so that Brainstorm's feed posts remove any emoji-type characters from the original :P | 21:16 |
| Dredd | <LjL> "joerg, worldsaviorcyber was a..." <- I banned them on matrix side for what it's worth | 21:22 |
| Dredd | But it seems they use new accounts all the time | 21:22 |
| Dredd | Nooooo not the mojis! | 21:22 |
| Brainstorm | Updates for Spain: +13738 cases (now 5.2 million), +37 deaths (now 88159) since a day ago — Netherlands: +21585 cases (now 2.7 million) since 21 hours ago | 21:38 |
| Timvde | So we decided here that people can get boosters 2 months after their J&J vaccine, 4 months after their AZ vaccine or 6 months after their mRNA vaccine, because they are "most effective" then. Is that actually grounded somewhere? I kinda suspect that it's more in function of waning immunity of those vaccines... | 21:47 |
| Brainstorm | New from COVID19 Vaccine Tracker: valerie: Altimmune Inc: AdCOVID → https://covid19.trackvaccines.org/vaccines/75/ | 21:52 |
| de-facto | id maybe studies like this one? | 21:58 |
| de-facto | .title https://www.medrxiv.org/content/10.1101/2021.10.13.21264966v1 | 21:58 |
| Brainstorm | de-facto: From www.medrxiv.org: Breakthrough SARS-CoV-2 infections in 620,000 U.S. Veterans, February 1, 2021 to August 13, 2021 | medRxiv | 21:58 |
| de-facto | thats not including AZ though | 21:58 |
| Dredd | Is it Moderna that is now called "Spidevax"? | 21:59 |
| Dredd | s/Spidevax/Spikevax/ | 21:59 |
| de-facto | yeah | 21:59 |
| de-facto | imho the best name so far, easy to remember | 21:59 |
| Dredd | Yeah | 22:00 |
| de-facto | mRNA-1273 referring to the sequence length btw | 22:00 |
| Dredd | I mean wth is a "comirnaty" | 22:00 |
| Dredd | Silly Pfizer | 22:00 |
| de-facto | or "Vaxzevria" | 22:00 |
| Dredd | Is that the AZ one? | 22:01 |
| de-facto | see what i mean? | 22:01 |
| de-facto | or "Vidprevtyn" | 22:02 |
| Dredd | 😀 | 22:02 |
| de-facto | its like their tea mug slipped and fell on their keyboard including hitting enter | 22:03 |
| Brainstorm | Updates for Germany: +70681 cases (now 6.1 million), +399 deaths (now 103308) since 23 hours ago | 22:03 |
| de-facto | uff | 22:04 |
| Dredd | 😀 | 22:06 |
| Dredd | If there is a new moderna vaccine what will it be called? | 22:07 |
| Dredd | New SpikeVax? | 22:07 |
| Dredd | SpikeVax 2? | 22:07 |
| Dredd | SpikeVax Plus? | 22:07 |
| Dredd | SpikeVax Omicron? | 22:07 |
| Dredd | SpikeVax Delta Plus is what I'm partial to myself 😛 | 22:07 |
| de-facto | SpikeVac Professional Plus Business Edition? | 22:08 |
| de-facto | apparently they will call it "mRNA-1273.529" | 22:09 |
| de-facto | that makes sense: the sequence length still is 1273 while its structure targets B.1.1.529 | 22:10 |
| de-facto | https://investors.modernatx.com/news/news-details/2021/Moderna-Announces-Strategy-to-Address-Omicron-B.1.1.529-SARS-CoV-2-Variant/default.aspx | 22:10 |
| de-facto | not sure about their internal name though, but SpikeVax Omicron kinda would follow that scheme i guess | 22:11 |
| aann | Moderna 2000 | 22:19 |
| joerg | LjL: Dredd: ((worldsaliver)) IP bans are useless, I'm aware. I escalated this to libera staff, they got filters for this. No idea if anything wil result from it | 22:21 |
| Brainstorm | New from COVID on Twitter: Eric Topol (@EricTopol): Good graph to show the reinfection risk for Omicron in comparison with prior variants of concern (data from yesterday's report from South Africa) medrxiv.org/content/10.110…ft.com/content/e742a4… pic.twitter.com/R8Vt2heWEI → https://twitter.com/EricTopol/status/1466878267344883718 | 22:21 |
| joerg | ><<de-facto> its like their tea mug slipped << Sotrovimab, regdanvimab - breaks my tongue | 22:25 |
| Dredd | <joerg> "LjL: Peter: ((worldsaliver)) IP..." <- It should probably get handled on the matrix side too ideally | 22:28 |
| Dredd | aann: 😀 | 22:28 |
| joerg | wait, you got dredd autoreplaced by peter? | 22:29 |
| LjL-Matrix | Well it can be reported. Not sure what else to do | 22:29 |
| Dredd | I dunno what you saw, on the matrix side I always see the special "pill" that is my user | 22:30 |
| * Dredd uploaded an image: (116KiB) < https://libera.ems.host/_matrix/media/r0/download/shortestpath.dev/tPqTFpyTXoHWHcyRVICwjubq/image.png > | 22:30 | |
| Dredd | Like that | 22:30 |
| Dredd | What do I show up as on IRC atm? | 22:31 |
| Dredd | Ah, it seems when I sent the message back to you that it was translated as my global matrix username and not my IRC nick for some reason. Testing: @pwr22:shortestpath.dev | 22:38 |
| Dredd | Well it left that alone. I can't @mention myself so can't try to reproduce it 😀 | 22:39 |
| Brainstorm | New from COVID on Twitter: BNO Newsroom (@BNODesk): BREAKING: England reports 75 new cases of Omicron variant, raising UK total to 134 bnonews.com/index.php/2021… → https://twitter.com/BNODesk/status/1466882799433134087 | 22:40 |
| Dredd | Oh dear | 22:40 |
| bn_mobile | Anyone have thoughts about Omicron? | 22:49 |
| bn_mobile | Have studied shown the results really are that much more severe? | 22:50 |
| bn_mobile | s/studied/studies/ | 22:50 |
| de-facto | its very new, i would assume we need at least several weeks of data such datapoints | 22:55 |
| de-facto | we have the sequence of its genome and know that it got a lot (32 in the s-protein, 10 of which in the receptor binding domain) mutations, hence probably some of them come with some new properties (such as evasion of antibodies raised against previous variants that would not fit on the surface of omicron= | 22:57 |
| de-facto | we also see quite a fast increase in cases in South Africa, so that is worrying | 22:57 |
| bn_mobile | First new cases have supposedly landed in the US now 😬 | 22:58 |
| de-facto | their population is quite young, hence its hard to tell how the severeness of Omicron induced COVID compares to previous variants | 22:58 |
| de-facto | in south africa i mean | 22:58 |
| Brainstorm | New from COVID on Twitter: Marc Veldhoen (@Marc_Veld): Of interest; "Heterologous combinations of spike encountered during infection and vaccination shape subsequent cross-protection against VOC, with implications for future-proof next-generation vaccines." This is in line with twitter.com/Marc_Veld/stat… → https://twitter.com/Marc_Veld/status/1466888138400444420 | 22:59 |
| Dredd | It certainly seems to be spreading around though | 23:04 |
| de-facto | .title https://ibz-shiny.ethz.ch/covid-19-re-international/ <-- choose "South Africa" then "Provinces" and look at the cases for Gauteng (yellow) | 23:06 |
| Brainstorm | de-facto: From ibz-shiny.ethz.ch: COVID-19 Re | 23:06 |
| de-facto | Gauteng: 2021-11-29: 1909; 2021-11-30: 3131; 2021-12-1 6169, 2021-12-2 8280 | 23:08 |
| de-facto | that looks horrible | 23:08 |
| Brainstorm | New from COVID on Twitter: Marc Veldhoen (@Marc_Veld): This means:1. Vaccination is and remains important for everyone; irrespective of infection status.2. Combinations of vaccines are very powerful3. It seems good to boost with current vaccines which act against all VoCs. → https://twitter.com/Marc_Veld/status/1466888140921131013 | 23:09 |
| de-facto | fucking hell | 23:11 |
| de-facto | a nonlinear fit to those datapoints give Cases_Gauteng[t] = 1390 6.1^(t/4) meaning those datapoints are consitent with Rt(4d) ~ 6.1 | 23:13 |
| de-facto | in the summer while they are aware of the nasty outbreak :( | 23:13 |
| de-facto | .title https://imgur.com/a/mOtmusw https://i.imgur.com/AajAx5D.png | 23:21 |
| Brainstorm | de-facto: From imgur.com: COVID SA: Johannesburg Gauteng Infections - Album on Imgur | 23:21 |
| de-facto | ok too few datapoints, but the few we have there are not looking good at all | 23:24 |
| Brainstorm | New from Retraction Watch: AHA “regrets any confusion” and is reviewing meeting policies after outcry over Covid-19 vaccine abstract: Days after a leading heart journal issued an expression of concern for a meeting abstract [... want %more?] → https://retractionwatch.com/2021/12/03/aha-regrets-any-confusion-and-is-reviewing-meeting-policies-after-outcry-over-covid-19-vaccine-abstract/ | 23:28 |
| Brainstorm | Updates for India: +14324 cases (now 34.6 million), +530 deaths (now 470254) since 23 hours ago | 23:30 |
| Brainstorm | New from Ars Technica: Science: COVID vaccinations spike in US as delta rages and omicron looms → https://arstechnica.com/ | 23:48 |
| Brainstorm | New from COVID on Twitter: BNO Newsroom (@BNODesk): Zimbabwe, where new coronavirus cases have surged from 27 to 1,042 in just one week, confirms at least 50 Omicron cases bnonews.com/index.php/2021… → https://twitter.com/BNODesk/status/1466900223859601409 | 23:57 |
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