libera/##covid-19/ Friday, 2021-12-10

LjLArsanerit, 3G, even in hotspot areas00:00
LjL(although that's not the terms we use)00:00
Arsaneritwhat terms do you use?00:00
ArsaneritI'm aware of green pass, but that's not so specific.00:00
LjL"normal green pass" and "reinforced/super green pass"00:00
LjLwe only have two things, and only had one until 3 days ago00:00
BrainstormUpdates for Barbados: +132 cases (now 26565), +2 deaths (now 246), +2367 tests (now 447564) since a day ago00:00
Arsaneritthat's not very clear00:00
LjLsuper green pass is 2G00:00
LjLbecause your G's are clear? :P00:00
Arsaneritno00:00
summonnersuper green pass? OMG South Park called it again00:01
Arsaneritin a language where almost all partizips are with a G, it's not great either00:01
LjL:P00:01
ArsaneritGeimpft, Genesen, Gestorben, Gesund, Getestet, Genervt00:01
LjLanyway, i think it was kinda better to have just one thing instead of making things incredibly confusing00:01
LjLand i thought our normal vs super was already confusing enough, but you have *more*00:01
Arsaneritafaik Germany has 1G, 2G, 2G+, 3G, 3G+00:01
LjLi think this is all being ridiculous theater and it's time for vaccines to be mandatory00:01
LjLwhy should i, as someone who got vaccinated "like a good boy", be scared of getting fined if i forget the correct version of my pass when i take a bus? when people who are not vaccinated CAN take a bus anyway as long as they do remember to get their test-based pass?00:02
Arsaneritunvaccinated people in Germany can visit bookstores but not flowershops00:02
LjLthey think they are "nudging" people to vaccinate but at the same time they are also dragging vaccinated people down and making them feel "meh"00:03
LjLArsanerit, that's pretty much a "lockdown of the unvaccinated" except without (i guess) an actual ban on leaving your home... but with a ban on getting into non-essential places. i don't think we're even remotely close to *suggesting* such an idea here, although obviously we will once we also hit 60k+00:03
DreddLjL: Clearly I am more important *stands up straight* 🎩 🧐00:03
LjL-MatrixDredd: that's funny of you to say *in italics*00:05
LjL-Matrixthey're pretty bendy!00:05
Dreddsummonner: Lol, they didn't get delta plus right though 😉. It should be Omicron Plus 😛00:05
summonnerDelta Plus Super Max00:05
LjL-MatrixI think all the media and politics people, and also regular people, not seeing that even the term is ridiculous, speaks to how fucked up things are being00:05
DreddArsanerit: The relationship between 3G and 3G+ seems invested compared to the other tiers00:05
Dreddsummonner: https://www.youtube.com/watch?v=qnqbOMWlFKs00:07
ArsaneritLjL: Yes, Germany has a semi-lockdown of unvaccinated now, as much as they had a lockdown for all a year ago (which never included a daytime ban on leaving the home)00:07
Arsaneritit's mildly interesting what places are and aren't essential00:08
Arsaneritin the first wave bookshops were not essential, in later waves they were and apparently still are.  To be honest I don't think lot's of people get infected at bookshops...00:08
ArsaneritThat has not a lot to do with epidemiologoy.00:08
summonnerDredd, I can't believe Randy was responsible for covid00:08
DreddDredd: Continuation of awesome scene 😛 : https://youtu.be/qzEoBrr9gRA?t=9300:08
Dreddsummonner: And Disney / Micky Mouse00:09
Arsaneritgoodnight00:09
DreddAH HA00:09
* summonner LOLs00:09
DreddThe panicked remote learning makes me seriously chuckle00:10
ArsaneritLjL: my workplace still has a "stop 3G" sign where it means to avoid "Geschlossene Räume, Gedränge, und Gruppe" (closed rooms, crowds, and groups), from an earlier wave in which they advertised AHA+L+A-3G https://praxistipps.chip.de/aha-regel-a-l-und-3g-was-formel-und-zusaetze-bedeuten_12575200:11
Arsaneritgoodnight00:11
LjLand then we wonder why people act insane00:12
LjLAHA+L+A-3G pls00:12
DreddSo they're using AHA to advertise now00:13
LjLaha!00:15
MerlinMp[m]<Arsanerit> "Geimpft, Genesen, Gestorben..." <- This is funny as you cannot prove youre Gesund ( nor Genervt)00:19
LjLhe left00:19
DreddWho?00:20
LjLarsanerit00:20
DreddAh right yeah sorry I forget that matters in IRC at times 😛00:20
DreddAnd since Merlin / Młp is a matrixer they likely did too 😀00:21
LjLthat's why i pointed it out00:21
de-facto.title https://covid19.sanger.ac.uk/lineages/raw?show=B.1.1.529&lineage=B.1.1.529&colorBy=lambda <-- something to watch closely00:22
Brainstormde-facto: From covid19.sanger.ac.uk: COVID-19 Genomic Surveillance – Wellcome Sanger Institute00:22
LjLcolorBy=lambda?00:23
Dreddde-facto: That shows 0 cases for my area but I know we have had at least one confirmed case the otherday00:23
DreddSo to confirm it then it must have been sequenced ?00:24
BrainstormNew from r/COVID19: COVID19: Breakthrough infections with SARS-CoV-2 Omicron variant despite booster dose of mRNA vaccine → https://www.reddit.com/r/COVID19/comments/rctpxl/breakthrough_infections_with_sarscov2_omicron/00:24
de-factonot sure they use PANGO lineages, hence its some function for number of sequences i guess00:24
DreddAh it's in the past quite a bit00:24
de-factoDredd, yeah it takes some time for reporting to end up in their dataset00:24
Dredd27th november00:24
de-factohttps://cov-lineages.org/lineage.html?lineage=B.1.1.52900:26
de-factohttps://outbreak.info/situation-reports/omicron?loc=ZAF&loc=GBR&loc=USA&selected=ZAF00:27
de-factohttps://covariants.org/variants/21K.Omicron00:27
BrainstormUpdates for Zimbabwe: +5189 cases (now 155817), +3 deaths (now 4723), +27065 tests (now 1.7 million) since a day ago — Canada: +4097 cases (now 1.8 million) since 23 hours ago — Botswana: +538 cases (now 196090), +1 deaths (now 2421), +23308 tests (now 1.9 million) since 2 days ago [... want %more?]00:38
LjLDredd, but also yes that's only going to be sequenced cases01:05
BrainstormNew from COVID on Twitter: David Elfstrom (@DavidElfstrom): Swiss study finds SIX TIMES the cases in poorly ventilated classrooms (those with over 2000 ppm CO₂) compared to better-ventilated ones. #COVIDCO2#Ventilate2Educate #COVIDisAirborneH/T @SamJCaustonswissinfo.ch/eng/society/st… → https://twitter.com/DavidElfstrom/status/146908218258504499801:20
BrainstormUpdates for Australia: +1715 cases (now 225629), +2 deaths (now 2084) since 23 hours ago — Syria: +107 cases (now 49008), +5 deaths (now 2798) since a day ago01:40
BrainstormNew from Virology.ws: A controlled trial of face masks for COVID-19: It will be some time before a substantial fraction of the human population is immunized to prevent COVID-19. In the meantime, widespread use of face masks can have an impact on disease, a conclusion suggested by results of a [... want %more?] → https://www.virology.ws/2021/12/09/a-controlled-trial-of-face-masks-for-covid-19/01:49
BrainstormUpdates for Switzerland: +17 deaths (now 11753) since 11 hours ago02:05
LjLthey showed on TV here the "no green pass people" have their own map site listing a ton of venues in Italy that let people in without checking the pass02:05
LjLthis is all a travesty, make it mandatory02:05
Dreddha ha02:12
LjL%title https://twitter.com/EricTopol/status/146911157641839001802:15
BrainstormLjL: From twitter.com: Eric Topol (@EricTopol): "Prior common colds with coronaviruses were supposed to have some protective effect for Covid. That turns out to be just the opposite https://www.cell.com/cell-host- [...]02:15
Dreddlol02:15
LjLthis looks like prior "cold coronavirus" infection makes the immune system initially think "well, this is just another of those little things, who cares", then when it realizes it'd bad, it overreacts02:15
* LjL publishes on ##covid-19 as an oversimplifier of pre-simplified graphs02:16
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): Prior common colds with coronaviruses were supposed to have some protective effect for Covid. That turns out to be just the oppositecell.com/cell-host-micr… @cellhostmicrobe pic.twitter.com/EW9WndBLaC → https://twitter.com/EricTopol/status/146911157641839001802:17
LjLyes i know02:17
LjL<Brainstorm> New from r/WorldNews: worldnews: Capital injection: Slovakia offers cash to over-60s to get COVID shots → https://www.reddit.com/r/worldnews/comments/rcw7td/capital_injection_slovakia_offers_cash_to_over60s/02:19
DreddLjL: But why wouldn't our vaccines end up doing that as the covies drift?02:19
LjLDredd, sssht ;(02:20
Dredd<sdfgsdfg> "it seems its true, 25 times more..." <- I'm in02:20
Dredd😉02:20
LjLi think we've gone from having zero studies about vaccine neutralization of Omicron to having too many of them02:26
LjLat least too many to keep in my head, but i don't feel like they are very concordant, except for "it's many times less effective"02:26
LjL(with governments somehow interpreting that as "oh, no problem then")02:26
LjLbut the nuances of which vaccine combinations help and which don't seem... i don't know02:27
Dredd<LjL> "at least too many to keep in..." <- Gov: Call up Pfizer! Cancel those new jabs! Moderna too!02:39
DreddSomeone: I'd just like to interject for a moment. What you're referring to Pfizer is actually a BioNTech designed vaccine......02:40
DreddOn a personal note, I do trust the NHS to do what the science on the whole shows is best within the power they have02:42
ublxeven when they used remdesivir?02:48
BrainstormNew from BBC Health: Covid-19: Face masks required in more indoor venues in England: The updated rules are among new measures to tackle the spread of the Omicron coronavirus variant. → https://www.bbc.co.uk/news/uk-5960266402:55
ublxhmm. apparently they still do. at least according to the guidelines i just saw they don't use it for people presenting more than 10 days after symptom onset02:56
LjLublx, what was wrong with using remdesivir? it seemed more helpful than water03:15
ublxit seemed over-hyped. as in less turned out to be less effective than the partial data release marketing-tease led us to believe03:19
ublxa seemingly harsh drug (side effects requiring careful consideration before use)03:21
ublxlong time now since i read about it but it seemed not at all obvious it should have been used03:21
* LjL shrugs03:21
LjLi think it was used widely, yes maybe it was over-hyped and the regulatory agencies bought into the hype03:21
LjLbut i wouldn't say it seemed absurd to use it, lacking any real alternative03:22
LjLi don't *know* whether it was a good idea to use it, i can't know, but i guess i'm just saying the NHS wasn't an outlier03:22
BrainstormNew from r/WorldNews: worldnews: Nearly 60 Million Latin Americans Starve as Pandemic Pushes Hunger to 20-Year High → https://old.reddit.com/r/worldnews/comments/rcxfvs/nearly_60_million_latin_americans_starve_as/03:24
sdfgsdfgso for those who are unvaccinated, are we supposed to get 3 doses to be safe now ?03:26
ublx£1900 for five days, according to The Times, about a year ago03:27
LjLsdfgsdfg, no, you're safe with just 2 because the vaccine works in a different way when injected into idiots03:27
sdfgsdfglol03:27
spokojni[m]Did you guys get your booster jab yet?03:27
sdfgsdfgnuh03:27
spokojni[m]Think of the grandmas03:27
sdfgsdfgwe dont even have the boosters here yet03:28
spokojni[m]LOL03:28
spokojni[m]I am unjabbed and untested03:28
spokojni[m]First this pandemic was fun and exciting03:28
spokojni[m]Now it's starting to piss me off, can't wait to get back to traveling03:28
LjLspeaking of being pissed off...03:29
* LjL taps fingers03:29
spokojni[m]What happened?03:30
ublx"Covid-19: Remdesivir has little or no impact on survival, WHO trial shows" - BMJ, Oct 202003:31
ublx"The ‘very, very bad look' of remdesivir, the first FDA-approved COVID-19 drug" - science.org, Oct 202003:31
BrainstormUpdates for United Kingdom: +50540 cases (now 10.7 million) since 23 hours ago03:32
ublxwhy are you unjabbed and untested, spokojni[m]?03:34
Malvoliouh. what's a good place to ask kind of a weird question03:34
ublxdid you stumble into this channel by accident?03:34
ublxMalvolio: get it over with03:34
Malvoliodon't think so. like what's the mildest strain of covid, and is it possible for an non-deadly version to exist that would spread natural immunity03:35
spokojni[m]ublx too much birocracy and I've been taught in elementary school that drug dealers give you first dose for free, before they hook you up. How about yourself, why did you took the experimental mRNA jab?03:35
ublxbirocracy?03:35
LjLmaybe you should've been taught spelling instead, that's one thing i was taught in elementary school03:36
spokojni[m]Yeah, I don't want anything from my country. I don't give anything to them and I don't expect anything from government.03:36
Malvolioif a variant emerges that basically does not kill people but is kind of like a common cold, would it not be best to allow that one to spread?03:36
spokojni[m]LjL English is not my native language, feel free to correct my grammar.03:36
LjLMalvolio, probably the original one, and, yes, but not particularly likely, despite the myth03:36
Malvoliohm03:37
LjLspokojni[m], okay: it's "bureaucracy" and "why did you take"03:37
LjLbut i'm being cheap with the jabs at you03:37
LjLi should charge more03:37
spokojni[m]LjL also I am under the influence of multiple psychoactive compounds right now, my grmmar might be affected by it. Probably not though, just not having enough practice.03:37
spokojni[m]LjL why did you took the experimental mRNA jab that doesn't work. Fear, job related, why?03:39
LjLspokojni[m], loaded question. this is not an anti-vax channel.03:40
Malvolio:-/ there exist people who were tempted to catch the original strain early...03:43
BrainstormNew from r/COVID19: COVID19: Epidemiological update: Omicron variant of concern (VOC) – data as of 8 December 2021 (12.00) → https://www.reddit.com/r/COVID19/comments/rcxtxk/epidemiological_update_omicron_variant_of_concern/03:43
LjLMalvolio, there still are people making "COVID parties" with the current strains03:43
Malvolioand we're seeing how their immunity holds against the later variants? the ones who survived...03:44
LjLMalvolio, it holds up decently when (if) you add a vaccine to it, it would appear. which makes sense, since also mixing different types of vaccines seems to help03:44
Malvoliohmm03:45
LjLwe urgently need multivalent vaccines, and honestly the point i personally feel like i would have to grant to the two fancy anti-vaxers above is that it would be nice if Pfizer didn't just keep trying to shove more of the *same* vaccine into... well, from their point of view it's shoving money into their pockets, and hustled up with the variant-specific vaccines instead03:46
LjLyes, at *this* point we didn't have any other real choice than just getting a booster of the same. but we shouldn't have reached that point.03:47
BrainstormNew from r/COVID19: COVID19: Emerging spectrum of post-COVID-19 syndrome → https://www.reddit.com/r/COVID19/comments/rcxvm7/emerging_spectrum_of_postcovid19_syndrome/03:52
Dredd<ublx> "even when they used remdesivir?" <- It works but not very well afaik?04:04
ublxhow could it possibly not, the NHS still uses it! haha04:07
sdfgsdfgcould we actually predict all the future mutations and make a multivalent vaccine ?04:08
Dredd<Malvolio> "if a variant emerges that..." <- Yes, and largely that would happen because we would stop caring about it and trying restrictions etc04:09
Dreddsdfgsdfg: No, it's a combinatorial problem04:10
sdfgsdfgexactly my thoughts, but the hype will definitely be profitable if Pfizer can partially prove they came up with a multivalent vaccine04:10
sdfgsdfgas long as they are partially useful, after 6th booster against a future variant we can call it multivalent anyways04:11
Dreddublx: Before these new drugs coming soon I think steroids was one of the best treatments were had at treating severe covid04:12
DreddMaking a vaccine that targets multiple variants effectively would also be possible but it's probably not worth the increased time and effort04:13
ublxyep. steroids seemed to get established as a standard treatment fairly quickly04:13
DreddThough I'm sure they're always trying to look for targets that are generally useful against many variants04:13
ublxamong a basket of therapeutics04:14
sdfgsdfgeucalyptus essential oil04:14
DreddBut people have been trying to work out a universal flu vaccine for a while now and we're still not there yet04:14
spokojni[m]Take NAC, there are some papers that support its use against Covid.04:16
spokojni[m]I take it as I am heavy smoker, makes it easier to cough tar out04:16
LjLplease don't just take people to "take things" if possible. the room can't provide medical advice. you can say what you're taking and your rationale04:17
sdfgsdfgthere are so many things we don't know about. We've never been able to solve aids or cancer either, not just a universal flu vaccine04:18
LjL<sdfgsdfg> could we actually predict all the future mutations and make a multivalent vaccine ? <Dredd> sdfgsdfg: No, it's a combinatorial problem  ←  not *all*, but i think this line of thought should be the road forward, personally. one promising thing is that we may know (or have readily available knowledge of) antibodies that would work on *all* current variants, and, what's more, on a bunch of *other* coronaviruses. so we can possibly predict what sort o04:19
LjLf places in the virus can hinder it a lot04:19
spokojni[m]LjL okay, well NAC increases natural production of glutathion, which I've read is good for the covid04:19
LjLsdfgsdfg, "cancer" is not one thing, but a large number of things, and we've made strides forward in some cases, and less so in others. AIDS is not "solved" but HIV is nowadays very treatable and we are able to stop the progression to AIDS04:19
LjLDredd, flu is a complicated beast, but i'd like to point out that two studies found that patients who had had SARS and then a COVID vaccine (in one case), and certain variants of COVID and a vaccine to the wild strain (if i'm not mistaken, i should check what this one actually said) developed antibodies that were active against *all* sarbecovirus, a large category of coronaviruses04:22
LjLso there is a reason to hope a universal vaccine *may* be at reach04:22
BrainstormNew from COVID on Twitter: Future Dr. Chris (@1andOnlyChrisN): “What? You want US to give at home covid tests for FREE to our citizens?”*proceeds to make the defense budget a literally psychologically incomprehensible amount of money* → https://twitter.com/1andOnlyChrisN/status/146914377878731162004:30
BrainstormUpdates for Netherlands: +19846 cases (now 2.9 million) since 21 hours ago04:34
BrainstormNew from r/COVID19: COVID19: Reinfection with new variants of SARS-CoV-2 after natural infection: a prospective observational cohort in 13 care homes in England → https://www.reddit.com/r/COVID19/comments/rcyzlx/reinfection_with_new_variants_of_sarscov2_after/04:50
BrainstormUpdates for Belgium: +16029 cases (now 1.9 million), +47 deaths (now 27463), +111755 tests (now 25.7 million) since 23 hours ago — Honduras: +124 cases (now 378547), +3 deaths (now 10419), +1785 tests (now 1.1 million) since 23 hours ago04:59
BrainstormNew from r/COVID19: COVID19: Heme oxygenase agonists—fluvoxamine, melatonin—are efficacious therapy for Covid-19 - Cell Stress and Chaperones → https://www.reddit.com/r/COVID19/comments/rcz925/heme_oxygenase_agonistsfluvoxamine_melatoninare/05:00
BrainstormNew from COVID on Twitter: Trevor Bedford (@trvrb): Based on available data, I don't feel comfortable yet speculating quantitatively about severity in the UK, US, etc..., but whatever level of severity it comes in at will determine how bad the inevitable Omicron wave will be. 21/21 → https://twitter.com/trvrb/status/146915781470252236905:18
BrainstormUpdates for Japan: +173 cases (now 1.7 million), +2 deaths (now 18371), +52677 tests (now 28.4 million) since a day ago05:42
BrainstormNew from The Indian Express: World: UK’s Omicron Covid variant cases nearly double in a day → https://indianexpress.com/article/world/britain-omicron-cases-london-uk-daily-covid-data-7665257/05:46
BrainstormUpdates for Bavaria, Germany: +21259 cases (now 1.2 million), +249 deaths (now 18425) since a day ago — North Rhine-Westphalia, Germany: +18850 cases (now 1.3 million), +101 deaths (now 19438) since 2 days ago — New York, United States: +11719 cases (now 2.8 million), +58 deaths (now 57992) since a day ago [... want %more?]06:38
BrainstormNew from The Indian Express: World: Omicron wave heads for UK, but It’s not clear how bad it’ll be → https://indianexpress.com/article/world/omicron-covid-wave-heads-for-uk-but-its-not-clear-how-bad-itll-be-7665447/06:43
BrainstormNew from MedicineNet: (news): 200 Million Americans Are Now Fully Vaccinated as COVID Cases Spike → http://www.medicinenet.com/script/main/art.asp07:59
BrainstormNew from COVID on Twitter: Florian Krammer (@florian_krammer): Die grosse Frage: Werd ich schon Omicron Daten zeigen koennen? Das wird spannend. twitter.com/junge_oeghmp/s… → https://twitter.com/florian_krammer/status/146921561072272998809:04
BrainstormNew from r/COVID19: COVID19: SARS-CoV-2 Omicron Spike Glycoprotein Receptor Binding Domain Exhibits Super-Binder Ability with ACE2 but not Convalescent Monoclonal Antibody → https://www.reddit.com/r/COVID19/comments/rd3qp7/sarscov2_omicron_spike_glycoprotein_receptor/09:23
BrainstormUpdates for Andhra Pradesh, India: +193 cases (now 2.1 million), +3 deaths (now 14460) since a day ago — Gujarat, India: +70 cases (now 827943) since a day ago — Punjab, India: +60 cases (now 603638), +2 deaths (now 16616) since a day ago — Haryana, India: +35 cases (now 771939) since a day ago09:33
BrainstormNew from Reddit (test): China_Flu: KAN News: researches from the Hebrew University gave a report to the the Prime minister, which state that the fifth wave had began, infection spread in all age groups, recommend to add limitations on people who enter the country from abroad [... want %more?] → https://old.reddit.com/r/China_Flu/comments/rd48bf/kan_news_researches_from_the_hebrew_university/09:42
BrainstormNew from Reddit (test): China_Flu: Researchers at the Hebrew University to Bennet: The Fifth Wave Began → https://old.reddit.com/r/China_Flu/comments/rd4bgj/researchers_at_the_hebrew_university_to_bennet/09:52
BrainstormUpdates for Grenada: +3 cases (now 5913), +175 tests (now 88750) since a day ago10:04
BrainstormNew from r/WorldNews: worldnews: UK PM Johnson loses poll lead after lockdown party revelations → https://old.reddit.com/r/worldnews/comments/rd4i0o/uk_pm_johnson_loses_poll_lead_after_lockdown/10:11
BrainstormNew from r/COVID19: COVID19: More infections in poorly ventilated classrooms → https://www.reddit.com/r/COVID19/comments/rd4qd9/more_infections_in_poorly_ventilated_classrooms/10:30
BrainstormNew from StatNews: The Omicron variant can likely outcompete Delta — and that could worsen the U.S. Covid-19 epidemic: Omicron is picking up speed in Europe, which has often served as a preview of what's headed the U.S.’s way. It’s an [... want %more?] → https://www.statnews.com/2021/12/10/the-omicron-variant-can-likely-outcompete-delta-and-that-could-worsen-the-u-s-covid-19-epidemic/10:39
BrainstormUpdates for Estonia: +588 cases (now 227446), +7 deaths (now 1845), +6716 tests (now 2.4 million) since 23 hours ago10:41
BrainstormNew from StatNews: Opinion: Vaccine skepticism is healthy. Cynicism is not: Only 17% of U.S. children ages 5 to 11 have received the Covid-19 vaccine. Parents should teach their children to weigh scientific evidence and shun the misinformation that cynics embrace. → https://www.statnews.com/2021/12/10/parents-vaccine-skepticism-healthy-not-cynicism/10:49
BrainstormUpdates for Nigeria: +754 cases (now 215918), +1 deaths (now 2981) since a day ago — Libya: +577 cases (now 377450), +11 deaths (now 5540), +3968 tests (now 1.9 million) since 21 hours ago — Namibia: +446 cases (now 130676), +2697 tests (now 807729) since a day ago11:06
BrainstormNew from The Indian Express: World: Safety, side effects, allergies and doses. Pfizer vaccine for 5-11 year olds explained → https://indianexpress.com/article/world/australia-pfizer-vaccine-children-safety-side-effects-allergies-7666018/11:27
Dredd<sdfgsdfg> "there are so many things we don..." <- Sure but what i mean is universal flu vaccines are a similar problem space but also an easier problem but we haven't managed it yet11:42
Dredd<LjL> "Peter, flu is a complicated..." <- Sure, but how well did they work and was that on earlier strains that were less virulent and evasive than delta and omicron? I mean I wouldn't get my hopes up too much is my thinking11:45
BrainstormNew from ECDC: Data on COVID-19 vaccination in the EU/EEA: The downloadable data files contain information on COVID-19 vaccination in the EU/EEA. The data are presented in the Vaccine Tracker and collected through The European Surveillance System (TESSy). → https://www.ecdc.europa.eu/en/publications-data/data-covid-19-vaccination-eu-eea12:23
BrainstormUpdates for Nepal: +232 cases (now 823786), +3 deaths (now 11552), +6472 tests (now 4.7 million) since a day ago — El Salvador: +1 deaths (now 3792) since a day ago12:45
xxanyone have a link to any data showing it is safe to regularly wash hands with 99% isopropylalcohol (IPA) and that it doesn't eventually lead to cancer?12:52
xxI am wasting my time arguing online with someone (a great use of my time) that claims it does cause cancer.12:52
BrainstormUpdates for Belarus: +1801 cases (now 671432), +18 deaths (now 5245), +25388 tests (now 10.6 million) since 22 hours ago — Laos: +1645 cases (now 86148), +7 deaths (now 231), +6734 tests (now 848756) since a day ago — Zambia: +162 cases (now 210724), +6578 tests (now 2.8 million) since 22 hours ago [... want %more?]13:16
Guest47Ok, so isolation day 4. Fever is gone. Still positive.13:19
genera...13:21
humpelstilzchen[thats good, always be positive13:22
generaeh13:22
Guest47I mean test positive. I see what you did there.13:24
Guest47Always look at the bright side, said the arsonist13:28
Guest47He was on fire13:28
BrainstormUpdates for Malta: +88 cases (now 40357), +2 deaths (now 470) since 23 hours ago13:29
BrainstormNew from r/COVID19: COVID19: Minimal cross-over between mutations associated with Omicron variant of SARS-CoV-2 and CD8+ T cell epitopes identified in COVID-19 convalescent individuals → https://www.reddit.com/r/COVID19/comments/rd7d1o/minimal_crossover_between_mutations_associated/13:40
squirrelis there any good data so far on how well current vaccines prevent you from being infected with omicron? as opposed to from being seriously ill14:10
BrainstormNew from EMA: Human medicine assessment reports: (news): Human medicines European public assessment report (EPAR): RoActemra, tocilizumab, Arthritis, Rheumatoid;Arthritis, Juvenile Rheumatoid;Cytokine Release Syndrome;Giant Cell Arteritis;COVID-19 virus infection, Date of authorisation: 15/01/2009, Revision: 36, [... want %more?] → https://www.ema.europa.eu/en/medicines/human/EPAR/roactemra14:18
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): Omicron's formidable immune evasiveness:First report of a cluster of 7 cases in young people all with 3rd shots 1-2 months previously, high anti-spike antibody levels. Symptoms mild to moderate papers.ssrn.com/sol3/papers.cf… pic.twitter.com/3lubDdy1SA → https://twitter.com/EricTopol/status/146929596701903667214:28
BrainstormUpdates for Switzerland: +15447 cases (now 1.1 million), +40 deaths (now 11776), +68726 tests (now 13.0 million) since 23 hours ago — Saudi Arabia: +48 cases (now 550136), +1 deaths (now 8851), +41369 tests (now 31.9 million) since 23 hours ago14:31
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): It's the immunity, stupid. 2 great explainers for why Omicron's apparent mild case profile is not necessarily about the virus and, unfortunately, not likely to be truenytimes.com/2021/12/10/opi… by @andrewpekosz twitter.com/nataliexdean/s… by @nataliexdean [... want %more?] → https://twitter.com/EricTopol/status/146929939197436723214:38
summonnerxx, just use soap, it's as effective at dissolving the lipid shell as high-alcohol hand sanitizer14:47
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): Considerably less Omicron wave hospitalizations and deaths in South Africa is more than welcome news, no matter how it occursft.com/content/87c0f3… twitter.com/EricTopol/stat… pic.twitter.com/SbkBZPMcFc → https://twitter.com/EricTopol/status/146930515768701337915:07
BrainstormNew from COVID on Twitter: Jeremy Farrar (@JeremyFarrar): @EricTopol UK may have highest or close to highest level immunity of any country in the world result of very high vaccine acceptance & a lot of transmission (running a hot epidemic see below) & yet now omicron doubling every 2d.  Impact of omicron in less [... want %more?] → https://twitter.com/JeremyFarrar/status/146931011633172070515:26
xxsummonner: I'm aware, the question however is about a link between cancer and IPA15:29
xxor rather the lack of the link15:29
BrainstormUpdates for Bangladesh: +269 cases (now 1.6 million), +1 deaths (now 28017) since a day ago15:33
BrainstormNew from StatNews: Pharma: STAT+: Pharmalittle: Fauci unconvinced Omicron-specific vaccines are needed; J&J rebuffed warnings about a diabetes drug → https://www.statnews.com/pharmalot/2021/12/10/covid19-vaccine-omicron-fauci-jnj-opioids/15:36
BrainstormNew from COVID on Twitter: Marc Veldhoen (@Marc_Veld): +Moderna reports strong data for flu vaccine pic.twitter.com/1T3i6924R5 → https://twitter.com/Marc_Veld/status/146931448062251827915:46
BrainstormNew from Virological.org: Latest topics: A fool’s errand: predicting the evolutionary future of the Omicron SARS-CoV-2 lineage:  Sergei Kosakovsky Pond and Darren Martin As Omicron spreads worldwide and more sequence data become available, we can begin [... want %more?] → https://virological.org/t/a-fool-s-errand-predicting-the-evolutionary-future-of-the-omicron-sars-cov-2-lineage/77415:55
BrainstormNew from COVID on Twitter: Josiah Grindrod (@JT_Grindrod): Always with the stupid exceptions. Just wear a fucking mask, vaccinated or not, it's not that hard. twitter.com/BNODesk/status… → https://twitter.com/JT_Grindrod/status/146932296090105446816:15
BrainstormNew from WHO Euro: Social workers caring for the most vulnerable: Christina’s story: Although often unseen, social workers provide important care to the most vulnerable. During the pandemic, they have visited patients in their homes, been close to [... want %more?] → https://www.euro.who.int/en/countries/denmark/personal-stories/social-workers-caring-for-the-most-vulnerable-christinas-story16:25
BrainstormNew from COVID on Twitter: Florian Krammer (@florian_krammer): Yep, looks like regular seasonal vaccines, but probably more reactogenicity. mRNA is not a silver bullet. twitter.com/Reuters_Health… → https://twitter.com/florian_krammer/status/146932780531810714216:35
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): More supportive data for our T cells to hold up to Omicronbiorxiv.org/content/10.110… → https://twitter.com/EricTopol/status/146933029829064294616:44
LjLDredd, you mean how well did they work on new variants compared to the current vaccines on current variants that just barely work if you have just had a 3rd booster that hasn't started waning yet?16:53
LjLDredd, https://www.nejm.org/doi/full/10.1056/NEJMoa2108453 and not sure which one the other study was, anyway this one was the most exciting16:54
LjLit was this one https://www.cell.com/cell/fulltext/S0092-8674(21)01062-X16:55
ublxmorning LjL16:56
LjLyes it's a bit early16:56
LjLi need to make a phonecall16:56
ublxalso xx, you shouldn't be using 99% for that. it's far less effective that ~70% for disinfecting purposes16:56
ublx*than16:57
BrainstormNew from Contagion Live: COVID-19 Booster Reduces Delta Variant Mortality by 90%: An Israeli study found that a third “booster” shot of the Pfizer-BioNTech vaccine reduced the risk of COVID-19 death by 90%. → https://www.contagionlive.com/view/covid-19-booster-reduces-delta-variant-mortality-by-90-17:04
xxublx: you're right, however that still doesn't lead to the answer of cancer yes or no. (I use 99% IPA to mix it with distilled water from my distiller, a tiny bit of aloe vera, and hydrogen peroxide. Overall it produces something that is ~80% IPA)17:06
de-facto.title https://www.medrxiv.org/content/10.1101/2021.11.11.21266068v217:09
Brainstormde-facto: From www.medrxiv.org: Increased risk of SARS-CoV-2 reinfection associated with emergence of the Omicron variant in South Africa | medRxiv17:09
de-facto.title https://www.samrc.ac.za/news/tshwane-district-omicron-variant-patient-profile-early-features17:09
Brainstormde-facto, the URL could not be loaded17:09
de-facto"Tshwane District Omicron Variant Patient Profile - Early Features"17:09
ublxmhm, xx. on that point you're also asking to prove a negative. which is.. not generally a fruitful direction17:10
ublxi guess you could get at a degree of confidence by exploring the literature on the safety profile of IPA in a skin contact context; deep dive google scholar. but you're not going to find a absolute assertion that it cannot cause... xyz17:11
BrainstormNew from COVID on Twitter: John Burn-Murdoch (@jburnmurdoch): Conclusions• Rate of Omicron cases resulting in severe disease is lower than past waves• But this is due in large part to dilution of that ratio due to mild cases in vaxxed & recovered• Numbers with severe disease are lower than past waves but [... want %more?] → https://twitter.com/jburnmurdoch/status/146933882276070604817:13
ublxmaybe come at it from the other side: explore reputable/credible literature that explores its potential for harm; you might find realistic descriptions of the limits of that potential17:15
xxthat's what I've been doing, and it looks completely safe to me, but I'd failing to see where the other person got the idea that there's some link between IPA and cancer17:19
xxso even a case report would be fine by me, but I'm not finding it17:19
xxobviously I'm ignoring the stuff where people sniff or drink it17:20
xxthat's bad for you mkay?17:20
ublxi guess if you take a bath in 99% IPA every day (wearing suitable breathing apparatus) it's going to constitute an immune challenge sooner or later17:22
ublxbut that's silly17:22
ublxi mean, just ask just ask them what their reason for belief is. then move on if it's nonsense17:23
BrainstormNew from COVID on Twitter: John Burn-Murdoch (@jburnmurdoch): Finally I’ll repeat that we owe an immense debt of gratitude to researchers, epidemiologists, public health officials and doctors in South Africa who continue to share timely, invaluable data and insights that leave other countries far better prepared [... want %more?] → https://twitter.com/jburnmurdoch/status/146933996192948224117:23
xxublx: I'd search for "does IPA dissolve human body" but I don't want to end up on yet another list17:23
BrainstormNew from COVID19 Vaccine Tracker: valerie: AnGes: AG0302-COVID19 → https://covid19.trackvaccines.org/vaccines/31/17:32
BrainstormUpdates for Denmark: +6599 cases (now 548780), +13 deaths (now 3009) since 20 hours ago — Netherlands: +17554 cases (now 2.9 million), +85 deaths (now 20457) since 23 hours ago — United Kingdom: +474 cases (now 10.7 million) since 22 hours ago17:38
BrainstormNew from COVID on Twitter: Dr Emma Hodcroft (@firefoxx66): "One shouldn't be afraid of the truth.One should be afraid of people who gloss over the situation and sweep it under the carpet.They are ready to sacrifice other things."- Thomas Guldener#COVID19 #Omicron #WinterWave → https://twitter.com/firefoxx66/status/146934527491304243217:42
BrainstormNew from COVID on Twitter: John Burn-Murdoch (@jburnmurdoch): Addendum: excellent illustration here from @enn_nafnlaus of how, in a faster wave like Omicron, the lag between cases & deaths effectively grows, making it even more vital to remember that numbers for severe disease will keep climbing for some time yet  [... want %more?] → https://twitter.com/jburnmurdoch/status/146934638011628750317:51
Raf[m]70% ethanol is more effective than 99%. I don't know about IPA. The idea is that 99% evaporates too fast and shortens the contact time17:53
lastshellhttps://www.bloomberg.com/news/articles/2021-12-08/s-african-weekly-excess-deaths-almost-double-amid-omicron-wave I guess this is not good17:59
BrainstormNew from COVID on Twitter: Sky News (@SkyNews): COVID-19: UK set to have one million Omicron infections by end of December - but boosters effective, say experts news.sky.com/story/covid-19… → https://twitter.com/SkyNews/status/146934866465729332018:01
BrainstormUpdates for Italy: +20490 cases (now 5.2 million), +118 deaths (now 134669), +716287 tests (now 124.9 million) since 23 hours ago18:03
BrainstormNew from The Indian Express (Health): Life-style: Children, coping with loss, are pandemic’s ‘forgotten grievers’ → https://indianexpress.com/article/lifestyle/life-style/children-coping-with-loss-are-pandemics-forgotten-grievers-7665389/18:11
LjLRaf[m], i think it's also that water is needed to get into the virus and make it "explode" (technical term)18:22
LjLlastshell, "but it's milder!"18:24
lastshellI had hopes18:24
de-factothat the young children are hospitalized in SA could indicate that its not milder, on the contrary18:25
de-factoif the very young children are the group with the least seroprevalence in SA they would be the ones that are the most comparable to previous waves (where they also were more or less immuno-naive), so if its them having more severe progressions (compared to previous waves) it means that this most likely is a property of the Omicron variant18:27
de-factothe illusion that "its milder" in the middle aged may be an effect due to them already "being trained" by having survived previous variants18:28
de-factoand honestly that also would fit with Omicron being more contagious, it most likely got both: 1) more biological fitness (even in the immuno-naive) hence replicates faster 2) more evasive capabilities, hence sero-evasive in those that already have pre-existing immunity18:29
BrainstormNew from COVID on Twitter: Trevor Bedford (@trvrb): @TWenseleers @gianlucac1 @kevinpurcell @JohnBurant I do think it matters. If R is lower and little r is the same then we expect the same rate of initial takeoff of the epidemic wave, but we expect it to crash sooner than the higher R same little r scenario. → https://twitter.com/trvrb/status/146935630914940928018:29
de-factodisclaimer: we dont have enough data to say that with certainty yet, but that young children get hospitalized more often with Omicron is not a good sign imho18:31
de-factomy guess would be: the virus becomes more aggressive with every new variant18:32
BrainstormUpdates for Namibia: +554 cases (now 131230) since 7 hours ago — Morocco: +175 cases (now 951267), +1 deaths (now 14795), +11883 tests (now 10.5 million) since 23 hours ago18:34
LjLanyway, potentially encouraging thread about mildness: https://twitter.com/jburnmurdoch/status/1469338725658341381 but please don't take it to drone on "it's milder it's milder". just follow the data wherever they lead ;(18:34
de-factobecause we keep it "barely" at Rt~1 instead of enforcing Rt<1, this means that its always stabilized at endemic where the most fit strains have an selection bias18:35
de-factowell yeah LjL if the assumption would hold that the majority of SA population already got some seroprevalence it would be the expectation value that future waves would be milder if not too far in the future, so its a bit difficult to say how much of that milder disease trajectory is counterbalanced by the more aggressive Omicron strain18:38
BrainstormNew from Politico: These countries went to US lobbyists to get ahead in Biden’s vax distribution plan: Nations are turning to DC lobbyists to get the tools they need to fight the pandemic. Global health officials say it’s all that’s wrong with the Covid fight. → https://www.politico.com/news/2021/12/10/foreign-governments-lobbying-covid-vaccines-52406818:39
-RSSBot[LjLmatrix- Zotero / COVID links Group / Top-Level Items: NEW thread: data show South Africa’s Omicron wave is resulting in less severe disease and death than past waves, though health officials say it’s too early to be sure, and severe outcomes will continue to climb. Story by me, @jsphctrl, @mroliverbarnes: https://ft.com/content/0ee745ce-ac55-46a9-9766-0b419821a79d https://t.co/6DClwASKVi (18:45
-RSSBot[LjLmatrix- https://www.zotero.org/groups/covid_links/items/CCEL7PVJ )18:45
LjLde-facto, curiosity question: when you asked and supposedly obtained aspiration, are you positive the doctor/nurse actually did it?18:47
de-factoLjL, if you want to set links at ft.com that are able to reach behind their paywall you would need to use that twitter shortener because it sets a cookie e.g. https://t.co/32sIrIQQ8M18:48
LjLde-facto, what i added is the Twitter thread itself18:48
de-factoyeah but that could be deleted i guess (the tweet)18:48
BrainstormNew from COVID on Twitter: John Burn-Murdoch (@jburnmurdoch): Excellent summary of the latest UK data on Omicron, including transmissibility, reinfection risks and the first real-world data on vaccine efficacy (significantly down for 2-doses, but boosters looking good!) twitter.com/kallmemeg/stat… → https://twitter.com/jburnmurdoch/status/146936111848959590818:48
LjLde-facto, so i should add https://t.co/32sIrIQQ8M ?18:49
LjLi'm not sure Zotero will like that18:49
de-factoi am not sure about zotero either, i just looked at "curl -I https://t.co/32sIrIQQ8M"18:50
LjLde-facto, okay, i had to add the ft.com link and then change it into t.co manually. also Zotero should have saved a copy *in* Zotero (it does that when i add stuff through the Firefox plugin)18:51
de-factonice18:53
de-factohmm actually looking at that ft article it seems hospitalization in the very young children was: Beta > Omicron > Delta18:54
-RSSBot[LjLmatrix- Zotero / COVID links Group / Top-Level Items: South Africa records fewer severe Covid cases in Omicron wave ( https://www.zotero.org/groups/covid_links/items/D8TNGTG5 )18:55
LjLde-facto, that graph is a bit perplexing tome18:57
LjLde-facto, it's almost like with Delta, *most people* needed hospital18:58
BrainstormNew from EMA: Human medicine assessment reports: (news): Human medicines European public assessment report (EPAR): Comirnaty, Tozinameran,COVID-19 mRNA Vaccine (nucleoside modified), COVID-19 virus infection, Date of authorisation: 21/12/2020, Revision: 16, Status: Authorised → https://www.ema.europa.eu/en/medicines/human/EPAR/comirnaty18:58
xxwait what? "most people needed hospital"?18:59
LjLxx, i'm not saying they did, just that https://www.ft.com/__origami/service/image/v2/images/raw/https%3A%2F%2Fd6c748xw2pzm8.cloudfront.net%2Fprod%2F06e320e0-59af-11ec-9b88-89664ab38e28-standard.png?fit=scale-down&source=next&width=700 seems to indicate that, and i might not be understanding it19:00
xxwhat a url...19:00
LjLalso correction: Beta, not Delta19:00
LjLxx, well i got an individual image url from an article that is paywalled :P19:00
xxI know, just saying I miss the times when it used to be http://www.webpage.com/path/to/pic.png19:01
xxthat graph shows a proportion of people that are *already* in hospital that needed the *extra* stuff (intensive care)19:02
ublxpremature, perhaps?19:04
xxublx: well, it seems to compare the first 25days for each variant19:04
xxso it is apples to apples I guess19:05
BrainstormUpdates for Montenegro: +219 cases (now 159433), +7 deaths (now 2347) since 23 hours ago19:05
xxexcept that those who were most susceptable to catch *and* die from it have died in the previous waves so they will not affect the current wave statistics19:05
ublxmaking that plot is also to suggest that the three waves are readily comparable in tshwane district, which strikes me as not obviously true19:06
xxwhy not?19:07
ublxwell suppose for example that a certain region just didn't have a beta wave. then the three way comparison would become kinda meaningless19:07
ublxmeaningless for the purpose it is being put to here, i mean19:08
xxbut they are using a district that *had* a beta wave (and delta and omicron)19:08
xxsure, it would not be correct to say "because these were the findings for this district, the same findings are expected everywhere else"19:09
ublx"didn't have such a wave" is an extreme way of making the point "in what way did this regions wave interact with the local populace"19:10
LjLxx, oh19:10
LjLxx, well in that case i go back to my usual warning about it "being milder"19:10
LjL'cause if you have more hospital patients in total, just fewer who need ICU, sure, it could mean it's milder, but it could also mean it's more severe, as in, patients who would have simply stay at home are now coming to hospital19:11
xxublx: unless I'm very misunderstanding something, that too would not matter much, because the graph is taking the proportion of people requiring intensive care out of all the people already in hospital19:11
xxLjL: or died in a ditch somewhere19:11
LjLif they're not severe enough to need ICU, good, but that means the ICU ratio goes down making it appear like it's milder, when it isn't necessarily19:11
de-factowell there is a history of those people that got hospitalized, so its not apples with apples (it would be if only immuno-naive would have been selected, but that status is unknown at moment of hospitalization)19:12
xxyeah, true19:12
LjLit's apples to rotten apples19:12
de-factoyeah kinda :P19:12
LjL(sorry not calling anyone rotten)19:12
xxideally you would want the graph split to immunonaive and not19:13
xxbut then you'd likely already be having trouble with extrapolating from even less data19:13
LjLanyway, it may (or may not) still be "apples to apples" for our own purposes: i.e. in South Africa most people are immune by having had the virus, but here most people are *also* immune thanks to the vaccines19:13
xxsouth africa is a special place anyway19:14
xxlots of people with comorbidities don't make it to adulthood19:14
LjLIsrael also, and in some of the same ways ;(19:14
ublxand ofc we expect the FT to make sensible use of data, so..19:14
LjLokay, not in that particular way19:14
xxnumbers coming from israel are just weird19:15
xxisrael might just be yet another weird place in the world with its own strange specifics, but sometimes the numbers really look like a statistician invented them rather than collected them19:16
BrainstormNew from r/COVID19: COVID19: Face masks reduce emotion-recognition accuracy and perceived closeness → https://www.reddit.com/r/COVID19/comments/rdep9i/face_masks_reduce_emotionrecognition_accuracy_and/19:26
BrainstormUpdates for Malawi: +59 cases (now 62147), +687 tests (now 449549) since a day ago — Canada: +20 deaths (now 29936) since 23 hours ago19:30
xxgood, I want people to listen to what I say instead of assume from what they can see on my face19:33
de-facto.title https://twitter.com/SallyBourliakas/status/146928631840871629419:35
Brainstormde-facto: From twitter.com: Sally Bourliakas  (@SallyBourliakas): "From Scotland today They have 95% capability to do S-gene drop out on covid tests: Show Omicron will overtake Delta & become dominant early next week. 1% last [...]19:35
de-factodamn.19:36
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): First data on booster vaccine effectiveness vs Omicron (581 cases):  drop in protection vs symptomatic infection by 2 doses (AZ ->0, Pfizer-> <40%) restored to ~75% with 3rd shot Pfizerassets.publishing.service.gov.uk/government/upl… [... want %more?] → https://twitter.com/EricTopol/status/146937404339658752319:36
de-facto.title https://www.gov.scot/publications/coronavirus-covid-19-state-epidemic-10-december-2021/19:40
Brainstormde-facto: From www.gov.scot: Coronavirus (COVID-19) state of the epidemic 10 December 2021 - gov.scot19:40
de-facto.title https://www.gov.scot/publications/omicron-scotland-evidence-paper/19:41
Brainstormde-facto: From www.gov.scot: Omicron in Scotland - evidence paper - gov.scot19:41
de-factoLjL, ^^19:43
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): The 95% CI presented here with relatively small number of Omicron cases overlap vs Delta, but certainly suggest less protection after 3rd dose.For Omicron, essentially no protective effect of 2 AZ doses, 3rd goes to 71% (42,86); 2 Pfizer doses to 34%, 3rd doses to [... want %more?] → https://twitter.com/EricTopol/status/146937675934298521619:45
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): Much more new beyond 1st look at Omicron vaccine effectiveness, summarized in a terrific thread by @kallmemeg twitter.com/kallmemeg/stat…— ~7% cases Omicron reinfections (0.4% Delta)— 3.2X adjusted odds of household transmission (vs Delta)— big growth [... want %more?] → https://twitter.com/EricTopol/status/146937896483350528219:55
BrainstormNew from COVID on Twitter: Gunhild Alvik Nyborg (@GANyborg): Interviewed in Dagbladet, on Omicron, children, & risk in schools. I recommend precautionary measures, as Omicron is in community spread in many local communities in Norway. The Norw. Inst. of Public Health wants to wait and see. In Norw. dagbladet.no/nyheter/advare… → https://twitter.com/GANyborg/status/146937996106892084120:05
BrainstormNew from Ars Technica: Science: Missouri tells health depts to “stop enforcing and publicizing” COVID measures → https://arstechnica.com/20:14
BrainstormNew from BBC Health: Three vaccine doses key for tackling Omicron: UK scientists shows two doses of a Covid vaccine are not enough to stop you catching the Omicron variant. → https://www.bbc.co.uk/news/health-5961500520:33
BrainstormUpdates for Mozambique: +379 cases (now 152965), +1 deaths (now 1942), +3072 tests (now 997829) since a day ago — Spain: +17012 cases (now 5.3 million), +60 deaths (now 88381) since 23 hours ago — Algeria: +210 cases (now 212434), +6 deaths (now 6132) since a day ago — Bahamas: +22 cases (now 22881), +3 deaths (now 708), +1390 tests (now 172649) since a day ago20:38
BrainstormNew from COVID on Twitter: David R. Martinez, Ph.D. (@David_RMartinez): Some of this already announced by companies. Looks like #Omicron fully evades the REGN mAbs. Same with Lilly. And only one of the two AZ mAbs (just given EUA yesterday) neutralize it. Sotrovimab from Vir going strong against Omicron. [... want %more?] → https://twitter.com/David_RMartinez/status/146939443601471488821:01
BrainstormUpdates for Germany: +53247 cases (now 6.5 million), +870 deaths (now 105880) since 22 hours ago21:03
BrainstormNew from COVID on Twitter: Gunhild Alvik Nyborg (@GANyborg): Detailed article with lots of info (also in this thread ⬆️) on Omicron in @zeitonline by @c_endt zeit.de/wissen/2021-12… twitter.com/c_endt/status/… → https://twitter.com/GANyborg/status/146939808842722099721:11
BrainstormNew from r/WorldNews: worldnews: Brazilian Ministry of Health suffers cyberattack and COVID-19 vaccination data vanishes → https://old.reddit.com/r/worldnews/comments/rdhejq/brazilian_ministry_of_health_suffers_cyberattack/21:30
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): The similarity/parallel of Omicron rapid growth across 5 countries (logit) twitter.com/TWenseleers/st… → https://twitter.com/EricTopol/status/146940763895787520521:49
BrainstormUpdates for Trinidad and Tobago: +898 cases (now 79237), +25 deaths (now 2361), +2489 tests (now 470218) since 23 hours ago — Dominican Rep.: +372 cases (now 409862), +4 deaths (now 4218), +4377 tests (now 2.5 million) since a day ago — Saint Lucia: +19 cases (now 13086), +596 tests (now 102297) since a day ago21:59
BrainstormNew from r/COVID19: COVID19: Ivermectin for Prevention and Treatment of COVID-19... American Journal of Therapeutics → https://www.reddit.com/r/COVID19/comments/rdikki/ivermectin_for_prevention_and_treatment_of/22:27
BrainstormUpdates for Dem. Rep. Congo: +643 cases (now 59851), +3 deaths (now 1118) since a day ago — Afghanistan: +257 cases (now 157858) since 10 hours ago — Central African Rep.: +170 cases (now 11912) since 4 days ago — Ethiopia: +157 cases (now 372868), +3 deaths (now 6822), +5530 tests (now 3.9 million) since a day ago22:43
TimvdeDoes anyone know if self tests can detect the omikron variant?22:55
TimvdeI mean, they're not very accurate to begin with, so I can imagine that they're totally worthless for omikron22:56
Timvdeomicron* in English, I guess22:56
BrainstormNew from COVID on Twitter: John Burn-Murdoch (@jburnmurdoch): The data from the dashboard on Covid-positive hospital admissions and patient numbers obviously remains very useful, but "excess critical care patients" comes into its own with Omicron where the number of patients in hospital *with Covid* but not *for [... want %more?] → https://twitter.com/jburnmurdoch/status/146942734285457408723:05
BrainstormUpdates for India: +8206 cases (now 34.7 million), +485 deaths (now 474875) since 23 hours ago — Spain: +83 cases (now 5.3 million) since 2 hours ago23:07
de-factoTimvde, yes23:11
de-factoRapid Antigen Tests (lateral flow) most likely attach their antibodies to the N-protein and PCR usually has several primers (e.g. in case one drops out such as the S-gene dropout with Alpha and Omicron so that the other primers still catch it)23:13
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): There's been a lot of new data for Omicron in the last day, much still preliminary, but here's my summary of the good and bad pic.twitter.com/pL8uiD7hfV → https://twitter.com/EricTopol/status/146942934300054732923:14
de-facto.title https://twitter.com/CiesekSandra/status/146492573474136883723:16
Brainstormde-facto: From twitter.com: Sandra Ciesek (@CiesekSandra): "Auch wichtig- die Antigentests (3 verschiedene von Roche, Siemens und Flowflex) sind auch bei Omicron positiv und funktionieren!" | 42l - nitter23:16
de-facto.title https://twitter.com/EckerleIsabella/status/146604959265140326923:16
Brainstormde-facto: From twitter.com: Isabella Eckerle (@EckerleIsabella): "#SARSCoV2 #COVID19 antigen-detecting rapid diagnostic test for #Omicron with a confirmed patient specimen. Credits to @MBekliz for her hard work to get these [...]23:16
Timvdede-facto: thanks!23:20
TimvdeI'm almost out of tests, so I was wondering if I should wait with ordering more :P23:20
de-factotry to get good ones23:21
de-factothere are big differences23:21
de-facto.title https://www.medrxiv.org/content/10.1101/2021.05.11.21257016v1.full-text23:22
Brainstormde-facto: From www.medrxiv.org: Comparative sensitivity evaluation for 122 CE-marked SARS-CoV-2 antigen rapid tests | medRxiv23:23
de-facto.title https://www.pei.de/DE/newsroom/pm/jahr/2021/22-antigen-schnelltests-sars-cov-2-vergleichende-sensitivitaetsbewertung-ce-gekennzeichneter-tests.html23:23
Brainstormde-facto: From www.pei.de: Paul-Ehrlich-Institut - Pressemitteilungen - Antigen-Schnelltests auf SARS-CoV-2: vergleichende Sensitivitätsbewertung CE-gekennzeichneter Tests23:23
de-facto.title https://www.eurosurveillance.org/content/10.2807/1560-7917.ES.2021.26.44.210044123:23
Brainstormde-facto: From www.eurosurveillance.org: Eurosurveillance | Comparative sensitivity evaluation for 122 CE-marked rapid diagnostic tests for SARS-CoV-2 antigen, Germany, September 2020 to April 202123:23
de-factoTimvde, ^^23:24
SpikevaxNeritgn23:32
Timvdede-facto: oooh, that's cool23:46
TimvdeLet me check the ones I always get here23:46
Timvde100%, 87%, 20%, 78%, that's not bad it seems23:47
TimvdeBut eh, what's CT? O:)23:48
BrainstormNew from r/COVID19: COVID19: High titers and low fucosylation of early human anti-SARS-CoV-2 IgG promote inflammation by alveolar macrophages → https://www.reddit.com/r/COVID19/comments/rdkfx1/high_titers_and_low_fucosylation_of_early_human/23:51
TimvdeAha, the number of cycli necessary to find virus particles23:52

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