libera/##covid-19/ Wednesday, 2021-12-15

LjL%title https://www.medrxiv.org/content/10.1101/2021.12.10.21267594v200:00
BrainstormLjL: From www.medrxiv.org: Estimates of reduced vaccine effectiveness against hospitalization, infection, transmission and symptomatic disease of a new SARS-CoV-2 variant, Omicron (B.1.1.529), using neutralizing antibody titers [...]00:00
LjLsouth africa vaccine effectiveness on omicron study00:00
LjLalso i've been shown a vaccine tracker (vaccine doses, not vaccine types) that has some graphs that you might like00:03
LjLthey aren't quite what i was looking for (correlations), but there are some ratios of things that i wanted to see00:04
LjLde-facto, https://covidvax.live/00:04
-RSSBot[LjLmatrix- Zotero / COVID links Group / Top-Level Items: covidvax.live: Live COVID-19 Vaccination Tracker - See vaccinations in real time! ( https://www.zotero.org/groups/covid_links/items/8U2WWGG6 )00:05
BrainstormNew from COVID on Twitter: Bloom Lab (@jbloom_lab): Congrats to @AllieGreaney for defending her PhD thesis today. Allie has made numerous valuable contributions to understanding mutations to the #SARSCoV2 RBD, and all of us at @fredhutch @uwgenome @UW_MSTP are proud to have such an accomplished young scientist as a [... want %more?] → https://twitter.com/jbloom_lab/status/147089077413695078500:06
LjLde-facto, you might be glad (even though the EU isn't) that we've decided to test people entering the country, *both* unvaccinated *and* vaccinated00:07
de-factonice one00:07
LjL(but since that includes Schengen people, the EU is asking questions)00:07
LjL(also not sure how that'll work at land borders)00:07
trbpgermany is thinking about not testing boosterd persons00:09
de-factothey they are not thinking... again00:09
de-factonot testing means we simply would not even know the breakthrough rates for boosted00:09
trbp2g+ should not be tested in some thoughts according the booster status00:09
trbpif that will be 3rd or 4th or 5th dose, who ever knows00:10
-RSSBot[LjLmatrix- Zotero / COVID links Group / Top-Level Items: Estimates of reduced vaccine effectiveness against hospitalization, infection, transmission and symptomatic disease of a new SARS-CoV-2 variant, Omicron (B.1.1.529), using neutralizing antibody titers ( https://www.zotero.org/groups/covid_links/items/8GV2A8ZP )00:10
-RSSBot[LjLmatrix- Zotero / COVID links Group / Top-Level Items: Omicron Appears to Evade Vaccines Better Than Other Variants ( https://www.zotero.org/groups/covid_links/items/9DPQ2CU4 )00:10
de-factoeveryone should get tested, regardless of any status, prioritize vulnerable and potential superspreaders, yet dont excuse the boosted, especially when we dont have a clue how long their protection lasts against Omicron00:11
BrainstormUpdates for Argentina: +4555 cases (now 5.4 million), +34 deaths (now 116826), +52869 tests (now 26.8 million) since a day ago — Mozambique: +733 cases (now 154520), +3648 tests (now 1.0 million) since a day ago00:11
trbpi guess it depends on how fast they are available and if they are about to expire or not00:11
LjL<CarlSagan_> [Ars Technica - Science] Omicron is rising rapidly in the US—3% of cases nationally, 13% in NY and NJ https://arstechnica.com/?p=1820744 2021-12-14T21:49:0600:14
BrainstormNew from r/COVID19: COVID19: Effectiveness of COVID-19 vaccines against the Omicron (B.1.1.529) variant of concern → https://www.reddit.com/r/COVID19/comments/rgjrec/effectiveness_of_covid19_vaccines_against_the/00:25
sdfgsdfgNetivot boy, 6, died of heart condition after getting flu – report00:29
sdfgsdfgHealth experts have concluded that a 6-year-old boy from Netivot who died suddenly on Monday was stricken with myocarditis as a result of complications from the flu, Kan reports. Yosef Naim, who had recovered a month earlier from the coronavirus, did not wake up Monday morning after going to sleep with a fever. The case had puzzled doctors, who investigated if the death was related to his prior coronavirus infection.00:29
BrainstormUpdates for Paraguay: +98 cases (now 463926), +3 deaths (now 16516), +5552 tests (now 2.0 million) since 23 hours ago — Vanuatu: +1 cases (now 7) since 8 days ago00:30
LjLso no effectiveness for a full course of AZ00:31
LjLgood riddance AZ00:31
LjLsdfgsdfg, two infections nearly on top of each other both stressing the heart?00:32
LjLi think i'd seen another paper in the past few days finding no efficacy of AZ against Omicron, but it might have been the same paper (this one was published today supposedly but who knows, with all these preprints)00:34
BrainstormNew from r/COVID19: COVID19: Stochastic social behavior coupled to COVID-19 dynamics leads to waves, plateaus, and an endemic state → https://www.reddit.com/r/COVID19/comments/rgk2ek/stochastic_social_behavior_coupled_to_covid19/00:35
-RSSBot[LjLmatrix- Zotero / COVID links Group / Top-Level Items: Effectiveness of COVID-19 vaccines against the Omicron (B.1.1.529) variant of concern ( https://www.zotero.org/groups/covid_links/items/C9JFC349 )00:35
Dredd<finely[m]> "It seem the current consensus is..." <- An appropriate hand sanitizer should have no problem taking the virus apart very effectively01:11
BrainstormUpdates for Norway: +6003 cases (now 328747), +5 deaths (now 1141), +102691 tests (now 8.9 million) since 23 hours ago — Reunion: +3374 cases (now 67237), +2 deaths (now 393) since 7 days ago — Botswana: +1554 cases (now 197644), +3 deaths (now 2424), +15422 tests (now 1.9 million) since 5 days ago [... want %more?]01:13
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): If you get exponential growth, you'd buy this UK projection, and realize what it portends for the US:"If Omicron infections continue to double every 2.5 days, as current estimates suggest, there will be a million people infected this coming Sunday alone."ft.com/content/d69a0a… → https://twitter.com/EricTopol/status/147090888234824908801:13
LjLDredd, i don't think that's what he meant, he was concerned that alcohol is mutagenic. i don't find that a big concern personally but i do agree that when possible, water and soap is the simplest option01:14
Dredd<LjL> "good riddance AZ" <- It still works as a way of getting to "booster ready" without depleting supplies of "booster appropriate" mRNA vaccines?01:15
LjLDredd, is it being *used*? not here01:15
DreddI dunno tbh, half of people in the UK have been AZ jabbed01:16
DreddSo it may still have been in active use for first jabs (especially given it's long shelf life in a normal fridge?)01:17
DreddAZ still seem to be selling it too01:17
DreddTo someone01:17
DreddOh so they meant mutagenic to themselves?01:18
DreddUnless you're doing something very questionable with your hand sanitizers it should be safe enough01:18
DreddI believe I read a paper on someone literally washing their whole body (bathing in it basically) with IPA and they got poisoning from absorbing too much of it over time01:19
DreddBut they did not get cancer and recovered soon after01:19
de-factoIPA is nasty01:19
minthos"Ethanol is mutagenic via its first metabolite, acetaldehyde." first google result. it's mutagenic inside the human body, not to viruses on our hands01:20
LjLminthos, Dredd: they meant mutagenic to the human body, presumably.01:21
LjLde-facto, how nasty? i mean if you don't wash yourself in it...01:21
minthosI wouldn't presume that but ok. the biggest concern is that it dries out the skin.01:21
LjLwell why would you presume the other way around? if anything neither of us should presume anything.01:22
minthosI'm just saying it's not a concern01:22
LjL*my* presuming was based on the fact that right next to alcohol being mutagenic, they said the best way to remove the virus was something else.01:23
LjLi agree it's not a concern01:23
LjLbut that's separate from what it is they've said :P01:23
Dreddminthos: Also soaps contain aldehydes too 😀01:23
Dreddde-facto: IPA is fine if in the same concentration it should be for a hand sanitiser01:24
DreddAnd in higher concentrations it evaporates basically instantly01:24
DreddSo not sure what you mean unless drinking it 😀 ?01:24
LjLDredd, the concentration that should be in a hand sanitizer is 70% though so uh pretty close to 100% in my book of %ages?01:25
* LjL spits out the alcohol he's drinking01:25
LjLyou could have told me sooner01:25
Dreddlol01:26
DreddIt's doubly funny since IPA is a type of beer 😉01:26
* de-facto slaps LjL01:26
LjLoh see!01:27
* Dredd slaps Brainstorm 01:27
BrainstormDredd: Do as you wish!01:27
LjLalcohol hurt me01:27
* LjL points01:27
LjL%ev slap01:27
BrainstormLjL: The adverb slap (meaning bang, slap, slapdash) is 0% positive, 0% negative - The verb slap (meaning slap, strike) is 0% positive, 0% negative - The noun slap is 0% positive, 0% negative01:27
LjLvery neutral01:27
* Dredd retires with Brainstorm to a private room01:27
* Brainstorm starts to disillusion Dredd with some cleanable frolicsomeness 01:27
LjLcleanable fomiteness01:27
Dredd<xx> "Peter: if you read further..." <- All the same, you can claim it is for your curiosity but you are still bringing it up again with the same person who has expressed they are happy with guest47 regardless01:31
BrainstormUpdates for Australia: +2764 cases (now 235530), +4 deaths (now 2117) since 18 hours ago — Panama: +382 cases (now 481438), +3 deaths (now 7391), +9535 tests (now 4.3 million) since 23 hours ago — Burkina Faso: +338 cases (now 16672), +6 deaths (now 296) since 7 days ago — Malawi: +235 cases (now 62615), +2 deaths (now 2310), +1948 tests (now 453249) since a day ago01:38
BrainstormNew from StatNews: Copy of Will we always need Covid-19 boosters? Experts have theories: STAT asked nine experts whether they think we face a future of endless Covid boosting. In the main, their answers were more reassuring than we expected. → https://www.statnews.com/2021/12/14/will-we-always-need-covid-19-boosters-experts-have-theories-2/01:51
sdfgsdfgnew horizons "Alcohol is mutagenic, cancerogenic and teratogenic"   - In addition, different indirect pathways may lead to mutations by alcohol. 🍺01:51
LjLprobably-important subthread: https://old.reddit.com/r/COVID19/comments/rg97dv/paper_claiming_a_lack_of_evidence_covid19/hoim2tr/01:53
minthospeople avoiding people reduces spread of viruses, who'd a thunk?01:54
sdfgsdfgone of the comments mention that it's proved that suicides also go down with lockdowns01:57
LjLactually the rest of the thread is interesting too, and it's really not that simple01:59
LjL(re: minthos)01:59
LjLi mean, it kinda is that simple, to a simplistic degree01:59
LjLbut it's mostly not the degree being discussed in the thread and, hopefully, in the most influential papers :P01:59
LjLi.e. "things have an effect": yes, pretty true. but which things and which effect, and is it to a meaningful degree, and is it worth it, and does it cause side effects - these are important questions02:00
minthossure, it's more complicated and relates to psychology, sociology, economics and so on but at the very basic level if we can stop interacting for a few months the virus will have nowhere to spread02:01
minthosthe problem is our inability to do that02:01
LjLdamn, i just wanted to reply to one claim but the i remembered i'm banned02:01
LjLbut in particular, i find this claim https://np.reddit.com/r/COVID19/comments/rg97dv/paper_claiming_a_lack_of_evidence_covid19/hokdspj/?context=3 factually wrong unless you're basically lawyering02:02
LjLand i'm disappointed one person purportedly behind the impetus to this retraction said something this stupid02:02
LjLi am in Italy, and i damned well know i couldn't technically have a walk with friends but could meet them indoors pretty much unimpeded, and that it would have taken unconstitutional methods to ensure i did otherwise02:03
minthosif I ever get my own country I will have a constitution that specifies that 24/7 curfews may be imposed as a precautionary measure when potentially dangerous infections are suspected02:08
LjLi hope you also have an advanced strategy to make people not starve etc during such02:09
minthosof course02:09
minthosfood delivery via drones, universal basic income02:09
LjLfair enough02:10
tyler0010[m]Don't forget the robocops and terminators to keep people in their homes. What could go wrong?02:15
minthosthey could be hacked, so I will need some humans in power armor as well02:16
LjLtyler0010[m], to be fair, a lot is going wrong even in our current implementation of society02:17
LjLbut i'm sure we could make it go wronger if we tried02:17
sdfgsdfghttps://media.springernature.com/full/springer-static/image/art%3A10.1186%2Fs12874-021-01304-y/MediaObjects/12874_2021_1304_Fig1_HTML.png02:17
sdfgsdfgthe same authors also published this nice article on open paper reviews etc https://bmcmedresmethodol.biomedcentral.com/articles/10.1186/s12874-021-01304-y02:18
sdfgsdfgmakes sense02:18
sdfgsdfg.title02:18
Brainstormsdfgsdfg: From bmcmedresmethodol.biomedcentral.com: Open science saves lives: lessons from the COVID-19 pandemic | BMC Medical Research Methodology | Full Text02:18
Dreddminthos: What about augmented humans? Either mechanically or with nanites?02:19
sdfgsdfgunreported conflicts of interest sounds like politics. I always had a feeling this would be true02:19
minthossure, when technology allows02:20
minthosalso genetic modifications02:20
* Dredd nods02:20
minthosand neural laces02:20
DreddI shall begin the work02:20
minthosgood, keep me posted02:20
LjLsdfgsdfg, first link gives me a 40402:20
* Dredd goes to replay Deus Ex: Human Revolution for inspiration 02:20
sdfgsdfgLjL hmm it was this figure from the page --> https://bmcmedresmethodol.biomedcentral.com/articles/10.1186/s12874-021-01304-y/figures/102:21
DreddThat's honestly my favourite game of all time02:21
DreddAnd I kind of want robot legs02:21
minthosI haven't played it but quake 4 had a pretty cool cyborg enhancement scene, I also like ghost in the shell, appleseed, stellaris and the culture02:22
sdfgsdfgroad rash was better02:22
Dreddminthos: Sounds like you'd enjoy it02:23
DreddIt features a conspiracy theorist radio host which is such a good capture of Alex Jones lol02:23
LjLsdfgsdfg, what would you say is their conflict of interest in this matter?02:25
minthosI liked the radio in fallout 402:25
sdfgsdfgno idea for this paper, but in general I think there might be a risk02:27
sdfgsdfgLjL   "On Vioxx, Topol wrote: "Sadly, it is clear that Merck's commercial interest exceeded its concern about the drug's toxicity" (2). More and more concerns are raised by scholars and major journal editors about the type and the quality of published evidence, often biased towards efficacy of new products. The industry, funding over 80% of trials, sets up a research agenda guided more by marketing than by clinical considerations. Smart statistical02:27
sdfgsdfg and epidemiological tactics help obtain the desired results. Budget for marketing is by far greater than for research."02:27
sdfgsdfghttps://pubmed.ncbi.nlm.nih.gov/18982834/02:27
sdfgsdfg.title02:27
Brainstormsdfgsdfg: From pubmed.ncbi.nlm.nih.gov: Big pharma and health care: unsolvable conflict of interests between private enterprise and public health - PubMed02:27
DreddWhat happened to Michael Yeadon? Do they have some sort of schizophrenia type of disorder?02:29
sdfgsdfghe's an ex-pfizer scientist who went nuts02:30
minthoscan't blame him02:30
DreddYeah I mean like do you think he is diagnostically mentally ill?02:31
DreddSame deal with a few other people like the guy who used to work on lipid nano-particle related stuff02:31
LjLsdfgsdfg, i've definitely seen at least one researcher vocally complaining that Merck's drug may be a reckless experiment02:32
LjLsdfgsdfg, anyway i was nudging in the general direction of a team of researcher writing a paper about the importance of the process of reviewing and potentially rejecting papers, and then doing it prominently with a COVID paper :P02:32
LjLDredd, Malone? or is there a third person i should add to my list of people who have been persecuted by pharma for speaking the truth, i mean, nutters02:33
LjLfourth*02:33
DreddLjL: yes that guy02:34
LjLDredd, some anti-vax shouter on TV today actually called him "the inventor of mRNA vaccines" without actually being corrected by anyone else in the study. instead everyone was just shouting. top-notch TV debates02:35
LjLin the studio*02:35
LjL(or just "the inventor of mRNA", i don't even know)02:36
DreddOh god, computer science people are amazing at misusing terms in ways that insult or diminish the experience or suffering of others: https://en.wikipedia.org/wiki/Schizophrenia_(object-oriented_programming)02:36
DreddLjL: I've seen "inventor of RNA" before02:37
minthosI don't think it insults or diminshes anything, but it does pollute google results02:38
DreddWith all due respect, it's a very particular medical term being misused and I'm glad it isn't popular02:38
minthosit's also the closest existing term for a particular phenomenon that didn't exist before and therefore has no proper name02:39
* Dredd is frequently reminded of the suffering he deals with due to his OCD when people refer to their enjoyment, preference or some small frustration they have related to order 🤦‍♂️02:39
LjLyou mean not nearly as popular as the actual use of the term schizophrenia to mean multiple personality disorder, or even paranoid-type-sort-of psychiatric disorder in general?02:39
LjLbecause that's a lot more popular than the very niche computer science use02:39
DreddLjL: It is infact mistaking it for DID from what I understand too yeah02:39
LjLwell, i'm saying the mistaking is pretty popular. the computer science term isn't.02:40
minthosI see your point with the OCD misuse, that has really gotten out of hand02:40
TelvanaHaving OCD myself I don't see how that would bother someone02:40
BrainstormUpdates for Anguilla: +69 cases (now 1592) since 3 days ago — Canada: +4222 cases (now 1.9 million) since 22 hours ago02:40
DreddTelvana: When you are literally losing your mind it can be a little frustrating for someone to misuse what you're going through02:41
DreddAnd it means people think they understand it but really don't02:41
Dreddand they will tell you that02:41
TelvanaWhat does that really matter? It's just their opinion.02:41
DreddOr argue that their satisfaction for having alphabetical books on their shelf that look all pretty02:42
* LjL takes note: never say "gosh, i'm dying" (of heat, laughter or something) in case he's ever around someone with a terminal disease02:42
DreddIs the same as your thing02:42
TelvanaNot sure why it should bother someone on a personal level, it's not like their opinion changes your life in any ways.02:42
DreddLol, there isn't a "should". It just does bother some people and that's all that matters. There's no right or wrong of it but in general I wish people were more educated02:42
DreddI'm not particularly bothered by it myself but I know others who are02:43
DreddI try and accept that people do that and so my small part to educate where possible02:43
DreddAs I am here02:43
minthosif the washed-out usage overshadows the original term it can be hard to be specific02:43
DreddTelvana: And similarly I'm not sure how or why you think my opinions, or some others, is wrong or that yours is relevant02:44
DreddWe perhaps suffer some similar things and can find common ground there but it doesn't mean everything about us or others is gonna be the same02:44
LjLthe thing is don't feel i've been educated on what OCD is, or what schizophrenia is... only that i shouldn't use them lightly, or at all unless i'm a psychiatrist, or something like that02:45
TelvanaI never said mine was relevant, did I? I simply said I wasn't sure why it should matter to someone.02:46
DreddSorry to get into it a bit but it urks me a little that when people bring up a type of suffering that people sometimes feel the need to diminish it?02:46
minthosI'm actually starting to get bothered by commercial products/companies choosing single words as names, you google a word and all the results are for some TV show or game or whatever, not what you're looking for02:46
DreddI kind of also expect someone with mental health experience themselves to be more aware of that and have a little more insight into the sensitivity of others02:46
TelvanaI simply don't care what others think, it's not my responsibility02:47
DreddSure, so why do you care what I think?02:47
Telvanaif I cared what others think I wouldn't work for the government02:47
TelvanaDredd: again, you're assuming I care what you think, and again, I don't - I made a passive comment, and you decided that it was about you02:48
Dredd.............02:48
DreddThere's no such thing as a passive comment02:48
minthospassive aggressive maybe :p02:48
DreddEspecially if you don't just respond "I didn't mean much by it" or some such02:48
DreddI care about what you think02:48
DreddThat's why I am conversing02:48
lastshellTelvana you work for the goverment ?02:48
DreddI'm not going to pretend otherwise 😀02:48
DreddAnd also others in this channel 😉02:48
lastshellthe goverment works ?02:49
DreddI have literally nearly lost my mind due to OCD and it has caused me so much suffering (and still does though thankfully I'm in a lot better place than before!) and many still are not so lucky and I wish they could be understood a little more02:49
TelvanaDredd: I care ABOUT the people in this channel, I just don't care what they think, that's all02:49
TelvanaAnd it's not too hard to denote a line there, at least, for me02:49
DreddTelvana: I don't think this is going anywhere productive so I'm gonna drop it now 🙂02:50
TelvanaDredd: And I am truly sorry to hear that, OCD is cruel and it's not a joke, but me personally if I worried about everything everyone has said about me I'd lose my mind more02:50
lastshellfirst case of omicron detect on my state02:50
DreddSure, I totally agree02:50
TelvanaIt's likely all over the USA already, sadly, lastshell02:50
lastshellyes, that is my fear02:51
DreddUnfortunately I don't think people really choose what worries / triggers them. if they did then OCD wouldn't be a thing and we'd just choose not to have it ☹️02:51
* Dredd had major issues with a friend getting angry at him for having OCD "I don't understand! Just don't do that! It's stupid! Just don't worry!"02:51
DreddThankfully we are both in a better place at dealing with that sort of stuff these days and learnt a lot from working through it02:52
* Dredd should shutup before the LjL bans me 😛 02:52
Telvanalol02:52
Dreddlastshell: how is omicron across the US in general?02:52
TelvanaI'd hope not, it's just friendly discourse02:52
DreddOver here in the UK it's already been in my city for a while02:53
LjLif this was friendly, i'm peter pan02:53
LjLwait...02:53
DreddAnd it's not a big city02:53
Dredd😧02:53
TelvanaLjL: hello, Peter :)02:53
lastshellDreedUSA has 34 states with confirmed omicron cases02:53
DreddLjL: I thought you were Tinkerbell?02:53
* LjL flies away02:53
* Telvana yeets LjL02:53
Dreddlol02:54
Telvanawee!02:54
LjL:[02:54
lastshellDreed but I thinkwe have omicron in all states already02:54
Telvanahehe02:54
TelvanaLast I heard it was 20 states02:55
* Dredd should have added that he knows people with and at risk of developing schizophrenia so it's a more personal and less academic thing for me too02:55
TelvanaIt's likely higher and it's just not detected yet02:55
LjLi think 33 states02:55
LjLsomething i linked02:55
Telvanaah, okay02:55
TelvanaI've been on vacation since Dec 4th so I haven't been paying attention much02:55
LjLHealth officials sounded the alarm Tuesday over the fast spread of the omicron coronavirus, which has now been detected in 77 countries worldwide and 33 states in the US—and is expanding quickly.  https://arstechnica.com/science/2021/12/omicron-now-13-of-cases-in-ny-and-nj-health-officials-brace-for-sharp-rise/02:55
LjLTelvana, exponential things grow quickly ;(02:55
Telvanayes, sadly02:55
DreddSeems likely it's everywhere over there now 😧02:56
TelvanaWhich is why I imagine it's likely in all 50 by now02:56
TelvanaWe move around too much for that to not be the case02:56
DreddDid anyone else see some one publish a statement from South Africa that the UK is overresponding02:56
LjLalmost certainly yeah02:56
TelvanaWell, maybe not Alaska/Hawaii02:56
DreddI mean.... I think not according to our data (which is better than theirs)02:56
lastshellLJL we got our fist case of omicron in NV02:56
lastshellso now 3402:56
Dreddis this more politicking to try and make SA look less like a plague ship?02:56
LjLDredd, i haven't, unless it's the type of thing where they complained about flights from/to them being halted02:56
DreddThey specifcally seemed to be talking about the UK's current response to Omicron domestically02:57
DreddI'll try to dig it up02:57
lastshellalso Dredd and LjL omicron makes up 3% of all US covid cases02:58
lastshellhttps://www.cnbc.com/2021/12/14/omicron-now-makes-up-almost-3percent-of-us-covid-cases-according-to-the-cdc.html02:58
lastshellso is just matter of time to spike02:58
TelvanaI was listening to someone rambling earlier and he said something that kind of intrigued me - what if there was a way to do "loss of function" on COVID02:58
Dreddhttps://www.dailymail.co.uk/news/article-10306211/amp/DR-ANGELIQUE-COETZEE-alerted-wider-world-Omicron-believe-Britain-overreacting.html02:58
TelvanaWhich opens up a wormhole in my head of things that could really go wrong with that idea02:58
DreddLjL: ^02:58
DreddApologies it's the Daily Fail02:59
lastshellat least is not infowars :P02:59
Telvanahaha02:59
Dreddhttps://www.dailymail.co.uk/news/article-10306211/DR-ANGELIQUE-COETZEE-alerted-wider-world-Omicron-believe-Britain-overreacting.html02:59
DreddNon AMP link since it doesn't work right on desktop02:59
DreddTelvana: Yeah, like engineering a more virulent but less dangerous variant?03:00
Telvanayes03:00
DreddI was thinking about that and also being scared about it too03:00
Telvanachoke out the dominant strain03:00
Telvanathe issue is, I see that going quite wrong due to the very nature of a coronavirus03:01
ublxgo big or go home03:01
ublxlets engineer a bacteria that eats coronaviruses03:01
DreddProblem is I suppose if it's harm is directly driven by it's virulence (like de-facto has suggested before) then it might not be possible03:01
TelvanaWho's to say we don't release something like that and it decides to just start killing people after it mutates, or it makes people grow a third arm03:01
Telvana:p03:01
DreddI suppose we could strap artificial covid anti-bodies to the outside of the virus to grab other ones03:02
Telvanawe should already know messing with nature is a bad idea03:02
LjLDredd, is that the doctor who somehow created the myth "it's mild"? ;(03:02
DreddOr just directly modify covid to be another part of our immune system 😛03:02
Dreddcoviception03:02
DreddLjL: I think so03:02
Telvanaublx: that would be a neat idea03:02
TelvanaSadly, the side effects would likely be bad03:02
Telvana"Hey, it kills COVID, but it gives you C-Diff"03:03
LjLso uhm let me check why my de-AMPing bot isn't working anyway, last time i only remarked that it wasn't, but didn't actually try to figure it out03:03
DreddIt's fine, we will just create a super-super-covid to kill the bacteria....03:03
DreddLjL: possibly because the daily mail seem to not be implementing it properly03:03
Dreddlol03:03
TelvanaI remember that was basically the premise of what happened when they tried to wipe out mosquitos with a virus03:03
LjLDredd, most viruses do affect bacteria!03:03
Telvanasomething went horribly wrong, I can't remember the whole story though03:04
LjLDredd, well, it not being proper is kind of the whole point why i made the bot thing :P03:04
Telvanaor maybe it was a bacteria, it was supposed to make them sterile, but it failed horribly03:04
LjLuhm03:04
LjLi've heard about mosquitoes that were meant to make other mosquitoes infertile03:04
LjLnot sure if that was by means of infecting them with bacteria first03:04
LjLbut, i didn't hear that it failed horribly03:04
DreddTelvana: ah so that explains the six foot tallk mosquitos I have around here wreaking havoc!03:04
Telvanahttps://www.cdc.gov/zika/pdfs/bti_fact_sheet.pdf03:05
DreddThere's so much wrong with this daily mail article03:06
Telvanahaha03:06
Dredd1. SA is in summer and UK is in winter03:06
TelvanaThey don't call it the daily fail for nothing, you know03:06
minthosZA03:06
Dredd2. You are biased03:06
minthosSA is saudi arabia03:06
DreddIf I could just interject for a minute, what you're referring to as SA is actually South Africa, or as I have taken to calling it: the bit at the bottom of Africa...03:08
LjLDredd, well, nice article. i couldn't disagree more.03:08
DreddGetting back to my critique of the author03:08
Dredd...03:08
* LjL chuckles03:08
minthosI will stallman all day about ZA vs SA03:09
Dredd3. You are saying that we should do what your data says for your country but in our country where out data says very different things03:09
Dredd4. Our data is widely accepted as better03:09
Dredd5. Our vaccination program is widely accepted as one of the best, which makes it all the more concerning that we see the trends we do03:09
Dredd6. Fuck off03:10
LjLTelvana, eh but what is the horrible thing about it?03:10
LjLDredd, those aren't possibly your best arguments!03:10
Dreddminthos: thanks for reminding me what the country code is but I wasn't trying to use it 😅. I was just trying to abbreviate South Africa because I cba to type it03:10
LjLmy arguments are mostly quote-based because they always are03:11
LjLso let me spam my way through the article03:11
Dreddha ha03:11
minthosthere is a country code, there is no reason to use another abbreviation except ignorance, which I'm on a mission to cure. you're welcome.03:11
LjL"And I should know — because I am the doctor who first raised the alarm about Omicron back in November." ← hence you're automatically biased. okay, that was your argument too! but wait!03:11
DreddI just find it very odd to say "Hey, you're seeing different things but, you know, you're wrong!03:11
LjL"I said then that we didn't know anywhere near enough about Omicron to make such judgments, or impose such policies. [masks, etc]" ← well, if we KEEP doing things when it's too LATE, instead of following the cautionary principle of assuming the worst while hoping for the best... i'd say it's a mildly (!) nice change we're doing it a bit differently this time03:12
minthosz and s are very close on the keyboard too, so there's no good reason to prefer pressing the wrong key03:13
LjL"I have been working with Omicron patients throughout that time, and I think it's safe to say that I know more than most about the effects it can have on human beings." ← i think that the fact you say you *must* know more than anyone because of *anecdotes, not data* is extremely concerning03:13
Dreddminthos: I would argue a lot of people might not know ZA (I do because of a job I worked at before but it isn't common knowledge here in the UK) and it was contextually fairly obvious I used SA to mean South Africa. Also seen others here do it 😛03:13
minthostime for them to learn then03:13
DreddPlus you know what I meant, and IMO as long as meaning is exchanged it's a valid exchange of info which is what language is really about03:13
LjLminthos, sorry, i already did know, and yet i used SA anyway03:13
LjLzue me03:13
LjL"As a general practitioner for more than 33 years, I am one of the foot soldiers who sees patients first. We clinicians deal day-to-day with real people, not statistical projections" ← err, that's obviously your problem with looking at country-wide statistics...?03:14
LjL"Don't just take my word for it. I have seen quite a few Omicron patients who have previously had the Delta variant and they will tell you that ..." ← don't take my word for it. take some people's word for it, through my word for it.03:14
minthosno it's fine, being a pain in the ass on irc is a response of appropriate magnitude considering the importance of the issue, though obviously insufficient to solve it :)03:15
LjL"... while no one ever wants to get Covid, they feel almost lucky that it was only Omicron they had the second time around." ← oh my, *second time*, you say! why would that be? couldn't they just get Delta a second time instead?03:15
DreddLjL: Yeah I agree here too. Also ties into the data quality thing that is showing in the UK some concerning signals on multiple axes. Plus all the great analysis of immune escape etc.03:15
LjLminthos, if you were me, you'd make a bot that corrects it every time03:15
LjLbut if i were me, i would ban it03:15
minthosit's good I'm not you then03:15
LjLminthos, that's probably good because it means we don't have sch... i mean MPD03:16
Dreddminthos: I touch type so SA is slightly easier and faster to type than ZA since ZA are on the same finger03:16
TelvanaMy main issue in my day-to-day job is lagging data and conflicting experts03:16
Dredd😀03:16
TelvanaThis whole pandemic has been the most confusing thing I've ever dealt with03:16
LjL"03:16
LjL'I alerted the wider world to Omicron - and I believe Britain is overreacting': Doctor Angelique Coetzee, the South African GP who knows more about its effects than anyone, calls for calm despite variant cases spiking 50 per cent in 24 hours03:16
LjLBy Dr Angelique Coetzee For The Daily Mail03:16
LjLPublished: 22:02 GMT, 13 December 2021 | Updated: 13:04 GMT, 14 December 202103:16
LjL    e-mail03:16
LjLi do apologize. how bad was it? :x03:17
Telvana"spiking 50" - that's a health admins wet dream03:17
TelvanaLjL: 5 lines03:17
LjL-MatrixOh, could've been worse03:17
Telvananbd03:17
DreddLjL: Lol "The insignificant number of people I see to form a statistically valid opinion have shown... but trust me, I do science!"03:17
LjL-MatrixI think I'll stop my critique here due to mispaste concerns :P03:17
Telvanathat's the rub03:17
LjL-Matrixyes you can continue in my stead thanks03:18
Telvanahaha03:18
TelvanaAnd let's be realistic here about Omicron, even at this point, we've got a relatively small sample size still03:18
DreddLjL: Lol, they are so glad that it's only the worst version they got? *phew*03:18
TelvanaAnd the samples I'm seeing aren't saying "it's mild"03:18
minthosdoubling every 40 hours - 30% lower rate of hospitalization - ZA already killed off most of their vulnerable population - maybe he's saying to stay calm as revenge for the travel apartheid03:19
Telvanaminthos: either that or he's trying to keep people from panicking again03:19
LjLDredd, by the way, on IRC we aren't actually seeing the things you're quoting ;( just your comments03:19
minthoslike the WHO by saying it's not airborne?03:19
Telvanayeah, that was quite the mistake03:20
TelvanaSame with the CDC back stepping on masks03:20
TelvanaThey screwed the pooch with that one03:20
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): The country with the highest cases/capita in the world now is Denmark, with 77% of its population fully vaccinated, 23% boosted, soon to be Omicron dominant.(The US is 61% vaccinated, 15% boosted, avg ~120,000 cases per day, w/ >66,000 hospitalizations) pic.twitter.com/RG2MVk8tfb → https://twitter.com/EricTopol/status/147094115719035699203:21
DreddLjL: woops re:quotes. The bridge really should consider number of intermediate messages as well as just timestamps!03:22
LjLDredd, and also maybe whether the thing you're quoting is anyone's message at all ;(03:22
lastshellhttps://nypost.com/2021/12/14/at-least-89-killed-by-mystery-disease-as-who-deploys-taskforce-amid-fears-of-outbreak/amp/03:23
DreddLjL: I have summarily complained in the relevant matrix room 😛03:25
Dreddlastshell: Super mega covid omicron delta rewards card plus variant?03:26
LjLDredd, i was a bit confused though, because you quoted something i quoted that contained that doctor's quote, i thought you were quoting the doctor directly, and the bridge was just killing your quotes regardless of them not being actual messages. but they were03:28
LjLanyway i've forgotten what else i was even going to nitpick on in the article03:28
LjLbut in summary, that doctor has a clear agenda, and so does the daily mail03:28
DreddYeah03:28
* LjL tries to be careful03:28
* Dredd uploaded an image: (1451KiB) < https://libera.ems.host/_matrix/media/r0/download/shortestpath.dev/agBneklbvNBXqhNyIXSzxNgh/image.png >03:29
DreddGuy from lastshell's link ^03:29
LjL"A hard lockdown would slow the process of Omicron making its way through the population and allowing people to develop the vital antibodies which will move your population towards 'herd immunity'." ← oh, herd immunity, where did i hear that before! BUT WAIT... didn't you say reinfections? with Omicron? on people who had Delta? so uhm...03:29
DreddIf the place is so flooded and messed up, why does he have a very expensive looking watch?03:29
LjL"The next variant that comes along might be slower spreading but more severe, and so we will need all the help we can get from such natural immunity." ← except if the next variant is as evasive as this one, and the "evolution computer" is fed by a SHITTON of cases, it will just re-infect everyone again?03:29
minthosyep03:30
DreddYeah, the virus will evolve to counter whatever we do03:30
Dreddthat's how evolution works03:30
DreddIt's not like it's got a static strategy and we can outsmart it03:30
BrainstormUpdates for South Korea: +7843 cases (now 536495), +69 deaths (now 4456) since 23 hours ago — Suriname: +45 cases (now 51289), +1 deaths (now 1179), +393 tests (now 164358) since 22 hours ago03:30
LjLi'm not sure i can judge how expensive a watch is from a distance, my dad has a pretty fancy-looking €30 watch from amazon :P03:31
DreddAlso, what the UK is doing now is about getting the scientifically proven level of immunity we need into the herd03:31
DreddAnd we already have herd immunity going on which is why omicron out competes delta03:31
minthosevolution works on numbers. larger numbers = more evolution = more risk of scary shit evolving03:31
LjLminthos, yes, that, which is i think *the* ultimate thing that makes Omicron Ominous03:32
LjLmore infections? sure, scary. more deaths? sadness. but more viruses, and worse ones? yikes for real!03:32
LjLanyway, this doctor has the agenda "it's mild", "herd immunity", "it's actually GOOD that we have this"03:39
LjLalmost makes me think...03:39
* LjL just coughs in a strange way03:39
LjLyou know, "That is because Omicron could potentially be of great help to us"03:39
LjLthat is just a sentence that i wouldn't dream of seeing from any scientist with a shred of sense of responsibility03:39
BrainstormNew from The Indian Express: World: Vaccine effectiveness against severe COVID drops slightly, still ‘significant protection’-WHO → https://indianexpress.com/article/world/vaccine-effectiveness-against-severe-covid-drops-slightly-still-significant-protection-who-7673545/03:41
LjL"it's slightly not milder"03:41
minthosI think it could be of great help to us by making people finally wake up and take the virus more seriously, by inflicting way more damage03:41
minthosin a way I think this pandemic has been good for us by highlighting a bunch of issues we still need to work on in society03:42
LjLminthos, i don't think anyone's going to work on them03:42
Dredd> Even one death is one too many. But will there be many more? Our experience in South Africa suggests not.03:42
DreddSadly, I don't think this is going to age well ☹️03:42
minthoswe're finally changing the orthodoxy that viruses aren't airborne03:42
LjLlast time i brought up that, whether or not it directly came from there, there should probably be a public discourse on virology labs, what they do, and how safely they do it... i was just told it's never gonna happen03:42
minthospeople are crafting corsi-rosenthal boxes and custom masks/ventilators etc03:43
DreddLjL: I also do not think society will work on those issues 😛03:43
DreddCall me a pessimist 😉03:43
minthoswe also got a big trial run of mRNA vaccine technology03:43
LjLDredd, you may not think it will, but still argue for it to. but xx seemed kinda defeatist on the matter in a way that becomes a self-fulfilling prophecy03:44
LjLif you shut down anyone who suggests talking about some matters with the argument "you'll never succeed in getting us to talk about such matters"... well, what can i say, yeah, that works.03:44
Dredd> Admittedly, our laboratories do not carry out genetic sequencing for every death, so we do not know how many Covid-related deaths can be attributed to Omicron and how many to other variants.03:45
Dreddloool03:45
DreddThis doctor seems fairly bad at logical thinking and I'm glad they aren't my doctor!03:46
LjLDredd, to be fair, the fact only one death has been counted so far makes me, uhm, mildly hopefully that it might indeed be somewhat mild03:47
LjLbut "hopeful this may help it make it less of a tragedy" shouldn't be confused with "hopeful this is actually a good thing we have omicron"03:47
DreddI hope so too but honestly I had set myself the expecation "based on math" that we will start to see UK deaths on december 16th03:47
DreddSo what happens in the rest of december could be worse03:48
LjLlet me just paste this again for a moment, i need to test the bot real quick03:48
LjLhttps://www.dailymail.co.uk/news/article-10306211/amp/DR-ANGELIQUE-COETZEE-alerted-wider-world-Omicron-believe-Britain-overreacting.html03:48
DreddAt this stage I have no data to actually suggest it's milder though, just wishful thinking03:48
LjLwell that was a pretty useless test03:49
* Dredd clubs Brainstorm with a large baguette03:49
* Brainstorm starts to lust after Dredd with some simple irrepressibility 03:49
LjLDredd, but what about deaths in South Africa?03:49
Dreddloool03:49
LjL"shouldn't" they really be more by now?03:49
DreddLjL: a lack of increases in deaths doesn't make it milder, just not worse than delta?03:49
DreddPlus everything is always better in summer03:50
Dreddthey don't sample well03:50
LjLDredd, my theory at this point is that the random sentiment analysis database that i fed Brainstorm with, which was generated by having a website ask people whether they thought about a given word positively or negatively, was simply hammered by people going after slightly sexual words :P03:50
DreddTheir population is badly vaccinated so their baseline death level is already higher than ours (meaning they are currently not relying on the buffer of vaccines)03:50
LjLDredd, well, a lack of increases in deaths *while* there is a sharp increase in cases, though03:50
LjLat least i think there is!03:51
LjL%cases south africa03:51
BrainstormLjL: South Africa has had 3.2 million confirmed cases (5.5% of all people) and 90172 deaths (2.8% of cases; 1 in 652 people) as of 6 hours ago. 20.4 million tests were done (15.7% positive). 18.5 million were vaccinated (31.4%). +23857 cases, +24 deaths, +68437 tests since a day ago. See https://offloop.net/covid19/?default=South%20Africa&legacy=no03:51
DreddI'm putting it down to bad sampling and sequencing tbh03:51
Dreddalong with the weather03:51
DreddBut let's see03:51
LjLi'm not even sure yet i "believe" in seasonality so :P03:51
LjLbut anyway, if you think we'll start seeing UK deaths tomorrow, then that's not a very long time to wait03:52
DreddThe next two weeks here in the UK should give a signal either way since we sequence all deaths03:52
LjLexcept if you're dying, then it might feel long03:52
LjLDredd, what was of that UK project to, like, help other countries git gud at sequencing?03:52
DreddLjL: I think they'll ramp up gradually, the 1 death has happened earlier than my schedule03:52
DreddDunno about the sequencing thing03:53
LjLDredd, uhm so yeah anyway, i do remember right, *stark* rise in cases in South Africa, but still no signal at all on deaths https://offloop.net/covid19/?default=South%20Africa&cumulative=no&smooth=yes&legacy=no (and i believe someone else calculated that by now there *should* be a signal, and this in turn was said a few days ago)03:53
DreddOmicron will soon be dominant here03:53
DreddBut the dominant decider of deaths will lag 3 or 4 weeks03:54
DreddAnd it's hard to factor for the effect overwhelmed healthcare might cause in increasing that03:54
DreddPlus then, assuming Boris gets his magic vaccine target hit, then we'd expect the effect of boosting to start dampening things down03:55
LjLand thing happening around f'ing new year ;(03:55
DreddSo it'll be hard to really pull out whether omicron is milder here without a proper analysis03:55
Dreddbasically I guess we'd expect to see deaths go up and then fairly soon after come down again03:56
DreddThough if healthcare gets overwhelmed that may cause an overlapping death increases that make it hard to judge the other signals03:56
DreddThat's all if it's not less severe03:56
LjLwell, i think the people who loudly claim it's mild mean it's *really* mild03:57
Dreddif it is less severe, then we see the deaths start to come down once it outcompetes delta03:57
Dreddafter a delay03:57
LjL(although i'm sure they'll change their tune after it's obvious it's not)03:57
Dreddand then further from the boosters03:57
LjLso if it's *really* mild, we should probably notice it03:57
Dreddmaybe with confounding increases in deaths simple due to healthcare bottlenecks03:57
DreddProper analysis should be able to extract out a signal even if healthcare is overwhelmed but I hope it isn't03:59
LjLwith Italy, i worry that the Omicron wave will be superimposed to the wave we're already having, *and* that in turn will happen right around Christmas / New Year, a perfect storm03:59
DreddAfaik the UK has now shut down all it's pop up covid hospitals and stuff03:59
Dreddand even our vaccine centers03:59
Dreddand the remaining ones have reduced capacity a bunch04:00
Dreddso we're pretty much caught with out pants down here04:00
LjLwith a few other European countries, i worry that their cases are now going down, it would be the end of their "natural" Delta wave, and people and governments might be like "whew, okay, can start relaxing now for a while"04:00
DreddWhich may be another reason for the strong reaction here04:00
DreddYeah the christmas timing is really bad04:00
LjLDredd, for a century or a couple England had "plague hospitals" that were always ready to be "turned on". i think we've become *a bit* too complacent about epidemics compared to past centuries.04:01
Dreddyeah04:01
DreddLjL: I think at least that you should see omicron supplant delta because it's just so moreish 😛04:02
LjLin my heart, it's still the Nu variant04:04
LjL(also quite embarrassing they "couldn't" call it the Xi variant)04:04
DreddI hope the LjL will permit this....04:04
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* LjL gets mildly irked04:05
LjLwhat can i do to convince my parents to wear friggin' Auras on their vaccine day?04:06
LjLmy dad just doesn't care much about using masks properly. my mom has panicky "can't breathe"-y feelings with tight-fitting masks, plus long hair that doesn't go well with the Auras' back-of-head straps04:07
LjLthey have the vaccine on saturday, there have been long queues and crowds in the vaccine centers lately, of course it's good they get it but i also think it could be a major source of infection compared to the few places they usually visit04:07
LjLi guess i can at least coax them into using the Korean masks, which i feel as a tiny bit better than the usual Chinese ones04:08
DreddAuras?04:10
Dreddah special masks04:10
Dredd"bad" masks are better than a "good" mask they take off I guess04:10
BrainstormNew from r/WorldNews: worldnews: Canada to advise citizens against non-essential international travel due to Omicron variant → https://old.reddit.com/r/worldnews/comments/rgol7i/canada_to_advise_citizens_against_nonessential/04:10
DreddLjL: have you looked at the comments on the daily mail article? The best and worst rated ones. Makes me very concerned about the UK populace lol04:11
LjLi have not, but, i can say this even before hand04:12
LjLthat is generally true of *all* random internet comments :P04:12
DreddIt's a cess pit of antivax04:12
DreddOutnumbering the other side like 10 to 104:12
LjL"It's more than that - digital IDs were certainly discussed when Bill Gates and a total of 8 World Economic Forum members had dinner with Boris in October."04:12
LjLit's the Daily Mail04:13
DreddAnd just some racists04:13
Dredd> Who has time listening to some stupid doctor from a failed country called South Africa04:13
Dreddetc04:13
LjLbut hey, at least, if these conservatives get mad at Boris, maybe they'll elect a Labour government next time. the ones with a Tory party leader.04:14
LjLpsh, they don't even know the term is "failed state"!04:14
Dredd> She knows FA. Wouldnt know covid from yovid. Looks stoned royally.04:14
DreddKeir Starmer is quite possibly David Cameron wearing a Scooby Doo style villain constum04:15
Dredds/constum/costume /04:15
LjL"So Britain is over reacting? What about Denmark? And Norway? China? France? And Ireland (North and South) She's in her own little world." ← i bet Ireland loves being called "South Ireland" :P04:16
DreddAnd Jeremy Corbyn (now an independent because he's been kicked out of labour) voted against the governments new covid measures 🤦‍♂️04:16
LjL;(04:16
LjLyou know, something vaguely related that i thought about, on how politics is hopeless04:17
LjLin Italy there was/is something that could be vaguely referred to as a left-wing government, right?04:17
LjLnot really, there's literally everyone but one party in it. but still, with a tactical majority on the left side, somewhat04:17
LjLso what happens is mostly left-wing people are "pro lockdowns", and right-wing people are anti-everything04:18
Dredd> I heard her on GB News and believe her more than SAGE & WHO and all the other doom bringers the government roll out04:18
LjLi know someone in Greece, they have a right-wing government there, they of course also did lockdowns and such04:18
DreddOh god, GB news04:18
DreddThe Farage channel04:18
LjLso guess what? he tells me that right-wing people are pro-lockdown, and left-wing people against04:18
LjLdoes it even make sense which technical side you're on anymore? the anti-greenpass protestors here were singing communist and fascist songs *at the same time*04:19
Dreddit's all a mess04:19
Dreddimo04:19
LjLand for the record, i'm actually against the green pass :P especially now that it's been extended and you need it to take any public transport, i think that's a bit much04:20
LjLbut on the other hand i think just mandating vaccination would be way saner04:20
BrainstormNew from The Indian Express: World: COVID-19: South Africa develops own coronavirus vaccine → https://indianexpress.com/article/world/covid-19-south-africa-develops-own-coronavirus-vaccine-7673573/04:20
LjLmandatory vaccinations: something i've been subjected to since about 40 years04:20
LjLmandatory QR codes to get on a bus: fuck that noise04:20
lastshellI was thinking way back mandate vaccines was not a good thing04:20
lastshellbut now I thing is no other option04:20
LjLi think it's just the time has come04:20
LjLin many ways04:20
LjLhad you asked me some months ago, i'd have said i was against... it's not really that i've changed my mind, it's just that when the vaccine was still an "early" thing i thought it made sense to let people be skeptical about it without forcing them. but now it's... not entirely clear to what extent it "works", to be fair :P but quite clear it doesn't make you drop dead04:22
LjLso once it's more or less on par with other vaccines we already have on the reasonable-safety front, go ahead, it's a pandemic, make it mandatory04:22
LjLthe ones among us who took it voluntarily are still alive04:23
LjLand i don't even have 5G reception04:23
LjLliterally, because that costs extra with my carrier04:23
lastshellsome conspiracy folks claim we are going to drop dead after 2 or 3 years of vaccination04:26
DreddLjL: My phone doesn't even do 5G!04:26
LjLlastshell, yeah but 3 years from now, they'll say it's 4 years04:31
LjLyou'll never make the "but what about long-term effects?" people happy04:31
LjLif it's shown as safe for 20 years, they still won't know what happens after 3004:31
lastshellvaccines just stay in your body from hrs to couple of weeks04:31
LjLwhich i can even see as a vague concern, really. we haven't had vaccines cause anything bad after a long time, but hey, there's always a first time. i just think it's a minuscule concern compared to COVID04:32
lastshellyeah the long term effect doest not compute04:32
LjLthe vaccines don't stay in your body for long, but the antibodies and other immune cells they elicit do04:32
DreddThose views largely come from a complete misunderstanding of how vaccines work. And a vivid imagination04:32
LjLand autoimmune issues definitely exist04:32
LjLbut it's so very theoretical04:32
Justin[m]1<lastshell> "hey guys I hear people get..." <- After the booster I felt pretty bad for a few days: bad headache, mild nausia. I had nothing worse than a sore arm for the first two shots. A friend had similar symptoms after the booster, but much more severe.04:48
minthosLjL: they should have called it the Ni! variant05:00
LjLminthos, surely ny05:00
minthosI prefer monty python memes over new york confusion05:01
BrainstormNew from COVID on Twitter: Dr. Pat Soon-Shiong (@DrPatSoonShiong): theatlantic.com/science/archiv…. COVID vaccines @ImmunityBio drives T cells ..mix and match strategy for a universal COVID . News soon → https://twitter.com/DrPatSoonShiong/status/147095932317809869805:26
BrainstormUpdates for Germany: +52233 cases (now 6.6 million) since 23 hours ago — Belgium: +9076 cases (now 2.0 million), +54 deaths (now 27685), +75040 tests (now 26.1 million) since a day ago — India: +247 deaths (now 476135), +2175365 tests (now 658.8 million) since 23 hours ago05:35
BrainstormNew from The Indian Express: World: Data indicate Omicron is milder, better at evading vaccines → https://indianexpress.com/article/world/omicron-variant-covid-research-vaccine-efficacy-7673556/05:45
BrainstormNew from r/WorldNews: worldnews: Zero Sinovac vaccine takers had sufficient antibodies for Omicron in HK study → https://old.reddit.com/r/worldnews/comments/rgr5it/zero_sinovac_vaccine_takers_had_sufficient/06:23
minthosI'm ok with the vaccine not being mandatory since it mostly prevents serious illness and death rather than being infectious06:25
minthosif anti-vaxxers want to die that's not really my problem, the hospitals will be overwhelmed anyway06:28
minthosthey do have a point about bodily autonomy, and as long as they are not a threat to public safety I think it's fine to indulge them06:30
BrainstormUpdates for England, United Kingdom: +52581 cases (now 9.3 million), +138 deaths (now 127479) since 23 hours ago — Ohio, United States: +9922 cases (now 1.8 million), +223 deaths (now 27594) since 23 hours ago — Parana, Brazil: +4117 cases (now 1.6 million), +16 deaths (now 40835) since 4 days ago — Veneto, Italy: +4088 cases (now 558205), +19 deaths (now 12084) since 23 hours ago06:37
BrainstormNew from The Indian Express: World: Hong Kong researchers urge third Covid-19 shot after new Omicron study → https://indianexpress.com/article/world/hong-kong-omicron-covid-vaccine-7673748/07:10
BrainstormNew from r/WorldNews: worldnews: J&J Shot Loses Antibody Protection Against Omicron in Study → https://old.reddit.com/r/worldnews/comments/rgs591/jj_shot_loses_antibody_protection_against_omicron/07:20
BrainstormNew from r/WorldNews: worldnews: Google To Fire Unvaccinated Employees → https://old.reddit.com/r/worldnews/comments/rgsgof/google_to_fire_unvaccinated_employees/07:39
BrainstormNew from MedicineNet: (news): Did Pandemic Lockdowns Worsen the Epidemic of Opioid Abuse? → http://www.medicinenet.com/script/main/art.asp08:07
BrainstormNew from r/WorldNews: worldnews: ‘A terrible tragedy’: US passes 800,000 Covid deaths – highest in the world → https://old.reddit.com/r/worldnews/comments/rgtc19/a_terrible_tragedy_us_passes_800000_covid_deaths/08:35
BrainstormNew from r/WorldNews: worldnews: Vaccine effectiveness against severe COVID drops slightly, still 'significant protection'-WHO → https://old.reddit.com/r/worldnews/comments/rgthq1/vaccine_effectiveness_against_severe_covid_drops/08:44
xx800k deaths where the people were infected with covid at the time of death, vast majority not dying of covid, and the US population increased by 2M in the same year08:46
xxseems almost insignificant in perspective08:46
sdfgsdfgminthos if you count those who refuse to get the booster as part of the antivax, they would be majority08:46
xxsdfgsdfg: most got the vaccine as a way of telling the gov "ok, leave me alone now, I'm vaxxed" but when they realized they'll need a booster every 6 months until the end of times then they said "f off gov, leave me alone, I already did enough"08:47
undefined_bobxx: whats your proof of 'vast majority not dying of covid'? (hint, its bullshit)08:48
xxundefined_bob: because they die of diabetes, heart attack, stroke, cancer, liver failure, ...08:49
xxcovid only makes existing conditions worse for the most part08:49
undefined_bobthats just not true. And most of those things are related to covid08:49
xxplease note that I am not denying that *some* definitely die of just covid08:49
xxbut the number of active, fit, previously fully healthy with no comorbidities people that die of covid is just miniscule08:50
undefined_boband your numbers for that are?08:51
xxundefined_bob: look into any of the things posted by the bot in here and you'll see what the people that die are like08:51
xxalso note that I am only talking about deaths, and not about serious complications or long-lasting effects08:52
undefined_bobthe the average age on the ICU has been decreasing for some time now. Its by far not only 70/80+ anymore08:54
undefined_bobits more like 40/50+08:54
xxI didn't say anything about age08:54
xxI know overweight people with diabetes that haven't exercised since middle school that will most likely die if they catch corona08:54
xxand they are 30+08:54
undefined_bobas older they are as more comorbidities they have in general08:54
xxright, but then we could attribute lots of strokes, heart attacks, cancers and organ failures each year to shingles, flu, other respiratory viruses, etc. because they are also known to make existing conditions much worse in a certain type of population08:56
sdfgsdfgso with something as stupid as contaminated polio vaccines, only 6 DECADES later we found out that they caused 5 different cancers  "These data suggest that there may be an increased incidence of certain cancers among the 98 million persons exposed to contaminated polio vaccine in the U.S.; further investigations are clearly justified." ependymomas (37%), osteogenic sarcomas (26%), other bone tumors (34%) and mesothelioma (90%)08:56
sdfgsdfgbut it's an older vaccine technology and not fair to compare of course08:57
xxsdfgsdfg: cause is a very strong word there that I am not fully convinced of through reading the existing literature on it. The most that I'd be comfortable with would be "strongly influenced cancer probablity in combination with environmental and lifestyle factors"08:58
xxthey did not properly control for all that based on what I read, they just wanted to publish a series of studies that bash vaccines08:58
xxor we simply live in a time where every study that's published always contains massive errors in controlling confounding variables for reasons unknown08:59
undefined_bobI dont like errors09:00
xxthe conspiracy theorist would say they do it in order to say "more funding and study is needed"09:00
sdfgsdfgprobably the "conflict of interest"09:00
sdfgsdfgthere is an entire library of research on "conflict of interest" with psychiatry09:01
xxit really is ridiculous that a random person on reddit is able to identify a factor in a study that scientists with a decade of experience "forgot" to control for and did not even mention09:01
sdfgsdfgunreported conflict of interest I mean09:01
jacklswhey bob09:01
undefined_boboh hey jacklsw09:02
sdfgsdfghttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC1805723/09:02
sdfgsdfg.title09:02
Brainstormsdfgsdfg: From www.ncbi.nlm.nih.gov: One flew over the conflict of interest nest09:02
sdfgsdfglol09:02
undefined_bobhow are you doing? Haven't seen us for a while09:02
xxmaybe we simply don't have the money to do studies well anymore, and so everything in science is done by the cheapest possible way as fast as possible09:02
xxwhich also means hiring the cheapest scientists too09:03
sdfgsdfgthis is the last reference I'll post on that, sorry https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1805729/09:03
BrainstormNew from r/Coronavirus: Daily Discussion Thread | December 15, 2021: Please refer to our Wiki for more information on COVID-19 and our sub. You can find answers to frequently asked questions in our FAQ , where there is valuable information such as our: → https://old.reddit.com/r/Coronavirus/comments/rgu08b/daily_discussion_thread_december_15_2021/09:03
xxsdfgsdfg: my issue with psychiatry is the demonstrated lack of reproducibility of results, which is a separate but related issue yeah09:04
sdfgsdfgyes, I had to study the origin story of Lobotomy because of that :D A chain read quest with:   https://www.researchgate.net/publication/11727503_Portrayal_of_Lobotomy_in_the_Popular_Press_1935-1960     "....study analyzed the content of popular press articles on lobotomy between the years 1935 and 1960. Both a qualitative and quantitative analysis provided evidence that the press initially used uncritical and sensational reporting styles, with the09:16
sdfgsdfg content of articles on lobotomy becoming increasingly negative through time. The initial positive bias occurred despite opposing views in the medical community, which provided a basis for more balanced coverage. These findings support the theory that biased reporting in popular press articles may have been a factor influencing the quick and widespread adoption of lobotomy as a psychiatric treatment."09:16
sdfgsdfgHowever, a cynical public soon began questioning whether the effects of a lobotomy were in fact worse than the disease it purported to cure. Unarguably more manageable post lobotomy, lobotomised patients were also left with irreversible changes in their persona, and were described as mental invalids and drooling zombies. Moniz himself came under attack for understating the complications, inadequate documentation and poor patient follow-up.09:16
sdfgsdfg Incredibly, despite such jarring criticisms, lobotomies became a mainstay of surgical psychiatric treatment. Until the advent of antipsychotic drugs in the 1960s when lobotomies rapidly fell into disfavour and faded into oblivion, some 5,000 lobotomies were performed in the United States alone09:16
sdfgsdfgisn't that insane that this happened only a few decades ago09:17
BrainstormUpdates for Germany: +52233 cases (now 6.6 million) since 23 hours ago09:31
BrainstormNew from r/WorldNews: worldnews: Amazon’s plastic waste soars by a third amid pandemic, report finds | Plastics → https://old.reddit.com/r/worldnews/comments/rguc5f/amazons_plastic_waste_soars_by_a_third_amid/09:50
Dreddxx: gonna need a citation about the "covid largely doesn't kill people"10:02
DreddThe only things I've ever seen pushing that view are covid-denying propagandas10:03
DreddIt just isn't supported by the science and the reason covid deaths are measured the way they are now is because that is the useful metric, as it's possible to compare covid / non-covid populations and also look at overall excess deaths vs the norm10:03
DreddCOVID-19 isn't a special thing - it's a term defined for the illness caused by SARS-COV-2, and illness which includes all the symptoms and causes of death you mentioned that "aren't COVID-19"10:05
DreddBy all means discuss this stuff but be prepared to bring actual sources when asked10:05
xxit's more of a technical difference. Kinda like saying driving fast doesn't increase deaths, suddenly reducing velocity to 0 does.10:05
DreddNo it isn't really. I do get your point but it's how the world works10:07
DreddA death can only be attributed to a condition through obvious correlation10:07
DreddWhich is what they are doing here10:07
xxwell, as a starting point for discussion https://www.cdc.gov/mmwr/volumes/69/wr/mm6928e1.htm10:08
xxAt least one underlying medical condition was reported for 8,134 (76.4%) of decedents for whom sup­plementary data were collected, including 83.1% of decedents aged <65 years. Overall, the most common underlying medical conditions were cardiovascular disease (60.9%), diabetes mellitus (39.5%), chronic kidney disease (20.8%), and chronic lung disease (19.2%) (Table 2). Among decedents aged <6510:08
xxyears, 83.1% had one or more underlying medical conditions. Among decedents aged ≥85 years, 69.5% had one or more underlying medical conditions.10:08
xxmy use of the word majority means >50%10:08
DreddComparable more to for example, Kidney failure at 70 being "You have died of age" vs kidney failure at 30 "This is not expected, there is some pathology, lets go find it"10:08
DreddThere might often be a pathology visible in the 70 year old but it's likely related to age10:09
DreddSo we call it "dying of age"10:09
xx(somehow quotes got removed, but you hopefully see the quotation)10:09
DreddThe statisticians calculating things aren't clueless buffoons that code-deniers / anti-vax people seem to think they are. They report values that are significant and countries are largely not expecting to get to 0 covid deaths but a stable low level (the UK has run like this a while)10:10
DreddIt's meaningful to compare mortality around covid diagnoses compared to those not around covid etc10:10
DreddWhich is what happens10:10
DreddBut saying COVID doesn't kill people doesn't really make sense10:11
DreddThat paper is very old and that people who die are at risk people is not any kind of argument for "COVID doesn't kill people"10:11
xxDredd: if you scroll down, you'll see I said "covid only makes existing conditions worse for the most part"10:12
DreddAnd with vaccines and culling of the herd by covid so to speak, the demographic of those with severe disease and death has shifted over time in most places10:12
xxso if I were to refine my statement, I'd say "covid is not the primary cause of death, the underlying conditions are the cause of death, exacerbated through covid"10:13
Dreddxx: Re-phrased: Covid is most deadly to those with vulnerability, who often are older or have pre-existing conditions10:13
Dreddxx: That's how *a lot* of deaths happen for a *lot* of things10:13
DreddMy Grandad died of Kidney Failure induced by flu10:13
DreddBut his cause of death is still flu related10:14
DreddHad he not got the flu then he would have lived10:14
xxyes, and we don't make a big deal out of those others things (or at least not such a big deal as we make with covid)10:14
DreddWe don't make a big deal of them as they are stable, manageable and treated to the best of our ability10:14
xxI'm all for implementing measures that stop the spread of covid, and reduce mortality etc. but at the same time I'd like people to see things in perspective10:14
Dreddbut COVID has killed a large number of people who would still be alive were we in an alternative universe where it did not arise10:15
Dreddthat is why we call them "covid deaths"10:15
BrainstormUpdates for Lithuania: +2215 cases (now 495686), +18 deaths (now 7039), +1592 vaccines (now 1.9 million), +21151 tests (now 6.4 million) since a day ago10:15
DreddI don't think anyone doesn't see them from that perspective - anyone who needs to that is10:15
DreddThe fact is, covid is associated with a relatively high mortality compared to endemic stuff and is a developing situation that is unstable10:16
xxe.g. I'd be happy if all countries closed down all international travel every year during a flu season10:16
DreddThat is part of why we care10:16
xxmake it a yearly thing, predictable and so on, so that businesses and people can prepare10:16
Dreddxx: That's a false equivalency - the situation is not the same. It's another line taken  by anti-vax and covid deniers frequently10:16
xxbut nowadays it's all covid covid covid and I'm sick of them ignoring all the other things10:16
DreddNo one is ignoring other things10:17
Dreddinfact covid measures improved flu outcomes too10:17
Dredd🤦‍♂️10:17
DreddI think I'm about done on this10:17
xxI'd love for influenza-b to be eradicated10:17
DreddI don't think flu is any more likely to vanish from this earth that covid, not soon with our current technology these days10:18
BrainstormNew from BMJ: Doctors are under more work pressure than during height of covid-19 pandemic in 2020: The pressures on doctors generated by the covid-19 pandemic have worsened during 2021 and this will have repercussions for doctors’ welfare, patient safety, and workforce retention, the General... → http://www.bmj.com/content/375/bmj.n3088.short10:20
DreddI've seen a doctors posting videos and such about how the boris vaccine push has come out of nowhere and is a big problem for them10:21
dTalDredd, link?10:21
DreddI can't find the exact video I'm thinking of but was reminded of it by brainstorm's link above10:23
DreddGoogling brings up this https://www.bbc.co.uk/news/uk-england-bristol-5963452310:23
dTalxx: I'm not sure what your overall point is. Is it that society is overreacting to covid?10:23
xxdTal: I'm mainly just rambling I guess10:23
undefined_bobI can agree with Dredd10:24
undefined_boband hi dTal10:24
xxfrustrated by lack of effective action worldwide due to politicians wanting to be reelected I guess10:24
dTalhowdy bob-who-has-yet-to-be-defined10:24
undefined_bobxx: its so wrong to only blame the politicians. Its the humans themselves who act stupid10:25
undefined_bobdTal: :D how are you doing?10:25
xxundefined_bob: that's an open question. Is it the factories causing polution due to demand, or is it he people who demand the stuff?10:25
xxis it the cows causing trouble, or the people who want to eat cows10:25
xxetc.10:25
xxevery societal problem can likely be split along those two lines10:25
dTalxx: I'm pretty uncomfortable with the thrust of your remarks. Especially the "only people with preexisting conditions die" thing, as a way to minimize the severity of covid.10:25
xxdTal: I don't see how that would imply that covid is not severe10:26
xxbut maybe I just don't express myself well10:26
dTalundefined_bob: Arm hurts, otherwise great10:26
undefined_bobstupiditiy can't be controlled by democratic politicians. Only by dictators with force10:26
undefined_bobdTal: got your 3rd shot recently? or why does your arm hurt?10:26
Dreddundefined_bob: And t10:27
xxundefined_bob: which is why I'm extra saddened that we can't know whether the data from north korea/china can be trusted. Maybe they solved covid, maybe they did not.10:27
Dredds/t/human behaviour is part of why the politicians behave that way too/10:27
dTalfor example you said <xx> covid only makes existing conditions worse for the most part10:27
dTalthe "only" does a lot of work there10:27
dTalwhat percentage of people don't have *any* existing conditions? A minority I'd say10:28
DreddI don't think there's anywhere in the world that hasn't portrayed that it is a specific subset of immunonaive individuals who are most susceptible10:29
DreddBut also, rarely, 32 year old fit marathon runners have died10:29
undefined_bobchinas numbers can be more trusted than north korea for example. Because regardless of all restrictions there are still unfiltered reports of citizens10:29
xxDredd: exactly the percentage that has been taking good care of their body their entire life, as one should, instead of relying on doctors to fix bad habits when they lead to trouble10:29
DreddThat's how stats works10:29
DreddAnd as mentioned earlier, vaccines have shifted the risk profile10:29
dTalfor example, obesity is an exacerbating condition. Fully a third of Americans are obese. That's *one* condition.10:29
DreddAlong with behaviour changes10:30
Dreddxx: No, disagree. overly simplistic view. See above10:30
DreddYou are totally ignoring things like asthmas10:30
Dredds/asthmas/asthma/10:30
Dreddvarious genetic conditions10:30
Dreddvarious immune conditions10:30
xxyes, and people really really shouldn't be obese, and the gov is unwilling to tackle that issue by e.g. increasing insurance costs to obese people or announcing that medical care will not be provided to obese people10:30
Dreddexercise is good for sure. I'd never recommend against it or say it's clearly not going to help10:30
xxsimilarly with smokers, or people who consume alcohol, etc.10:31
dTalThat won't fix the problem, it'll just further exacerbate the class warfare10:31
xxwe already kinda do it with denying lung/liver transplants, or putting those people at the end of the list10:31
Dreddxx: Lol, that won't work. It doesn't work for people taking dangerous substances either. Controlling people, or trying to, also doesn't help people stupidly not taking vaccines when there's effectively no downside for them 😉10:31
dTalit's also extremely ethically... shall we say "problematic"10:32
xxDredd: I have no data to support my statement, but I have a hunch that if people knew they wouldn't receive any medical care, then they'd take measures to take better care of their own help in order to not need medical care10:32
DreddIt's basically eugenics10:32
xxwhich would also include taking vaccines10:32
dTalokay but not providing medical care to people is like, evil10:33
undefined_bobthey should pay for it10:33
xxthis way, people know they'll receive medical care worth hundreds of thousands of dollars if they get a severe covid, despite not taking the vaccine10:33
undefined_boblike they already have to in some countries10:33
dTalwhy don't you just line up the town and shoot obese people 1 by 1, every day10:33
xxand that just rubs me the wrong way10:33
Dreddxx: that view is based on the mistaken idea that people just don't see that not being obese is bad so they shouldn't do it. They already know and don't want to be that way and are usually unhappy about it. But it's not that simple to just stop being obese10:33
BrainstormUpdates for Estonia: +655 cases (now 229869), +1 deaths (now 1869), +7420 tests (now 2.4 million) since 23 hours ago10:33
DreddSome people are naturally less prone to it, and some people find it a lifelong struggle10:33
Dreddsome people are in the middle10:34
Dreddbut it's clearly a common problem10:34
undefined_bobI meant only people who get unvaxxted covid10:34
dTalframing obesity as a personal failure is deranged10:34
xxDredd: it's my lifelong conviction that preventing obesity can be solved by not eating too much. North Korea has managed it. (I'm only half-sarcastic here)10:34
dTalwhen a third the population is obese, it's clearly a systemic problem10:34
undefined_bobthats true10:34
Dreddxx: have you suffered with obesity a lot in your life?10:34
DreddI'm all for sugar taxes and things like that. Not blocking healthcare for people who aren't desirable10:35
xxDredd: I was obese once after a bad life experience, and became fit two years later.10:35
DreddEspecially in countries like the US where people have to pay for it, it makes no sense10:35
xxmorbidly so I guess, BMI over 3510:35
xxnow I'm at 22 I think10:35
undefined_bobI'm not, I'm more like the opposite of obesity. Like I'm too slim10:35
dTalthis is like saying that a lot of people seem to be getting lung diseases from asbestos poisoning, so rather than banning asbestos we'll just... not treat them10:35
DreddSo your obesity was situational and not a lifelong struggle? And your view is coloured by this?10:35
dTaland hopefully that will make people avoid asbestos10:35
DreddLots of people still smoke despite it obviously being even more harmful than obesity etc10:36
xxDredd: I can't tell what has shaped my views, the least I can admit is that I personally experienced obesity, and managed to get out of it by just not eating too much10:36
Dredddespite insane prices, taxes, pictures of dying people and deformed organs on packages10:36
xxDredd: but imagine they'd be refused medical care, that might be a wakeup call10:36
DreddBecause the issue is more complicated is all I'm saying10:36
xxor at least refused *free* medical care10:36
DreddIt hasn't worked for smoking10:36
DreddOr for drinking10:37
dTalxx, you do realize that this is an evil mindset10:37
xxI'm not aware of any place actually implementing what I am suggesting10:37
DreddI've seen you post several times things like "exercise is the answer"10:37
Dreddetc10:37
xxdTal: eh, I don't really concern myself with evil10:37
dTalit shows10:37
DreddThat's overly simplistic10:37
xxthere are too many people, that's where I am coming from I guess10:37
DreddAnd also a misunderstanding of the wider issues10:37
dTalcrikey10:37
xxand I am a supporter of vhemt.org10:37
Dredddouble crikey10:38
dTalhumans will not go extinct voluntarily, that's an obvious given10:39
dTalso I wonder what they really hope will happen...10:39
Dreddthere's a lot of oversimplifications on that page / including ignoring the obvious issues10:39
DreddE.g. "If sex is an urge to procreate, then hunger’s an urge to defecate."10:39
BrainstormNew from StatNews: Will we always need Covid-19 boosters? Experts have theories: STAT asked nine experts whether they think we face a future of endless Covid boosting. In the main, their answers were more reassuring than we expected. → https://www.statnews.com/2021/12/15/will-we-always-need-covid-19-boosters-experts-have-theories/10:39
xxdTal: if people volunatrily breathe in asbestos despite being told not to, and presented ways of not doing it, then yeah, don't treat them for asbestosis or related cancers10:39
DreddIt's clearly written by someone with no understanding of human psychology10:39
DreddOr even animal psychology10:40
dTalxx: ...are you serious10:40
xxdTal: about which part?10:40
dTalYou missed the entire point10:40
DreddThere's a lot of asbestos around that people don't know about10:40
dTalNobody "voluntarily breathes in asbestos"10:40
DreddI have been exposed to asbestos dust by incompetent builders sent to my flat by my landlord years ago10:40
xxDredd: well, one is voluntary action (smoking cigarretes), the other is involuntary (accidental exposure to asbestos)10:40
dTalpeople breathe asbestos situationally, accidentally, through constraints or pressures of their career10:41
xxthat's where I draw the line10:41
DreddI was comparing smoking to over-eating, not to the asbestos btw10:41
dTalyou've got this puritan idea that obese people are obese because of a personal moral failing and they deserve to be punished and have their human dignity stripped10:41
dTalbecause you yourself had a minor run-in with it and beat it pretty easily, and so you have no sympathy10:42
xxdTal: I don't think it has anything to do with any personal moral failings, I think it just has to do with eating more calories than needed10:42
dTalbut dude a third of americans are obese10:42
Dreddxx: that again is overly simplistic10:42
DreddOn a thermodynamic level, that is the problem10:42
dTalbut why do people do that10:42
xxthat's like saying a third of americans own slaves - that doesn't make it alright (yeah a bit of a strawman, but you get the point)10:42
Dreddbut we are not some machine that has badly tuned parameters10:42
Dreddand we do not function like one10:43
dTaldo they wake up one day and go "gee I'm gonna go out and eat too many calories so I can be unhealthy"10:43
DreddThe point is why do the people eat to much? and how do I get them to stop? incase you are not following10:43
DreddAnd those are individual, multivariate and complex issues10:43
DreddInvolving human psychology10:43
DreddAs well as situational issues10:43
DredddTal: glad to see we're on the same sort of page10:44
xxI prefer thermodynamics to human psychology10:44
dTalwhat do you mean "prefer"10:44
DreddI am obese right now techinically (at least I think I am)10:45
DreddI have been this way many times in my life10:45
DreddI have also been underweight10:45
xxit means I know how to solve the obesity epidemic through thermodynamics (calories in, calories out) than through human psychology10:45
DreddI also am in some stupidly high percentile of the population if you measure my IQ or do some cognitive battery on me but yet I am still overweight10:45
DreddDespite knowing many reasons I shouldn't be10:45
dTallets not forget that the reason we're talking about obesity is because of covid lethality10:46
DreddAnd even having a fairly robust practical knowledge of modern human psychology10:46
dTalthe subtext here is that we shouldn't worry about covid too much because it only kills people who deserve it10:46
xxdTal: not the subtext I am going for though10:46
DreddYeah fuck that10:46
DreddI only mention myself as an example of why it's fairly silly to say "Yeah, you eat to much, don't do that and that is easy" and give an example10:47
xxwe should worry, and at the same time there should be a media massage 24/7 to get people to exercise, get fit, stop being obese, get active, move, eat healthier, ... and present options on how to do all of that. Instead of just saying "here's a vaccine, take it, covid is over".10:47
Dreddxx: you are again saying one thing despite having done the opposite. You literally said that covid doesn't really kill people it's other things. And that people should exercise and that will make it not kill people. They die because they're obese10:48
dTaland that we should refuse medical care to obese people as an incentive10:48
xxcovid could have been an opportunity to improve the health of global population, if the desire was there to push that message10:48
DreddYou can claim you aren't saying that but that doesn't make it true, even if you believe it10:48
dTalwhich is another way of saying as a punishment10:48
DreddAnd that you can operate with that view is because you are a human and human beings are capable of self-delusion and magical thinking, perhaps?10:48
Dreddsigh anyway yeah I'm done again10:49
DreddI need to work10:49
BrainstormNew from EMA: Human medicine assessment reports: (news): Human medicines European public assessment report (EPAR): Pregabalin Pfizer, pregabalin, Anxiety Disorders;Epilepsy, Date of authorisation: 10/04/2014, Revision: 24, Status: Authorised → https://www.ema.europa.eu/en/medicines/human/EPAR/pregabalin-pfizer10:49
xxprobably, there's definitely gonna be some DK involved, but at the same time it is hard to see 2 years go by when I personally saw what an individual can achieve in 2 years.10:49
dTalxx: you're putting aaaaall the responsibility on the individual, and your only suggestions for what government should do is to think new and cruel ways to put the responsibility on the individual even more10:49
dTalit really seems like you have an empathy deficit10:50
xxI can emphatise with people, but I have zero sympathy with those who only expect others to fix them instead of working on improving oneself10:50
dTalwhen you're at the stage of denying medical care to a third of the population to teach them a lesson, you really need to take a step back and rethink10:50
Dreddxx: feel free to discuss your views, this has gone pretty off topic though so lets let this drop here relatively soon. If you share these views repeatedly as facts and without evidence though it may be grounds for bans or muting in future if it's excessive as has happened before. The room is not really a place supportive of more fringe views around covid and the pandemic10:51
dTaltake some time to reflect on what "evil" is and why you should care about it10:51
xxdTal: if you scroll back, I said "announcing that medical care will not be provided to obese people". That can mean giving everyone 2 years to get fit.10:51
xxbut yeah, I accept that this is not strictly covid related, so I'll stop with this line of discussion10:51
Dreddxx: I want to clarify "if it's excessive as has happened before" doesn't mean you've done it before btw. I mean in the case of other users 🙂10:56
xxDredd: don't worry, I know what you mean, I'm not a special snowflake, I fully accept and understand your point.10:56
BrainstormNew from PubMed: Yutaka Saito: Preclinical Efficacy and Clinical Feasibility of a Novel Aerosol-Exposure Protection Mask for Esophagogastroduodenoscopy → https://pubmed.ncbi.nlm.nih.gov/34905818/11:18
Dreddhttps://www.bbc.co.uk/news/uk-wales-5965662611:55
DreddInteresting outcome11:55
DreddThey mention her mother is dying which sucks11:59
DreddGiven her reversal of her views, I wonder if it's of COVID related stuff?11:59
BrainstormNew from ECDC: Data on COVID-19 vaccination in the EU/EEA: Data in various file formats with information on COVID-19 vaccine doses administered, manufacturers, and target groups in the EU/EEA. → https://www.ecdc.europa.eu/en/publications-data/data-covid-19-vaccination-eu-eea12:25
dTalokay I am starting to feel a trifle wobbly12:59
BrainstormNew from ScienceNews: In 2021, COVID-19 vaccines were put to the test. Here’s what we learned: Vaccines can’t single-handedly end the pandemic, but they are still essential in the fight against the coronavirus. → https://www.sciencenews.org/article/covid-coronavirus-vaccines-review-pandemic-202113:04
BrainstormUpdates for Nepal: +252 cases (now 825016), +6 deaths (now 11565), +9212 tests (now 4.7 million) since 23 hours ago13:15
BrainstormNew from COVID on Twitter: Marc Veldhoen (@Marc_Veld): If you haven´t already done so; after J&J a booster is highly recommended at least 2 months after the vaccination. Boosting with J&J after RNA vaccines is also good.ema.europa.eu/en/news/covid-… → https://twitter.com/Marc_Veld/status/147109068985749094413:23
BrainstormUpdates for Malta: +168 cases (now 40892) since 23 hours ago — United Kingdom: +493 cases (now 11.0 million) since 18 hours ago13:34
BrainstormNew from Politico: Six MEPs sanctioned for breach of EU health pass rules: Six MEPs were sanctioned for breaking the European Parliament’s health pass rules, which require anyone entering the building to show their EU Digital COVID Pass, Parliament President David Sassoli said at the [... want %more?] → https://www.politico.eu/article/six-meps-sanctioned-for-breach-of-eu-health-pass-rules/13:42
BrainstormNew from r/WorldNews: worldnews: Omicron spreading so fast it threatens Britain's hospitals → https://old.reddit.com/r/worldnews/comments/rgy6lh/omicron_spreading_so_fast_it_threatens_britains/13:52
xxwith the speed it is spreading now, is there anything that could be done *today* so that hospitals are not overwhelmed in 10-14 days?13:54
xxright now the numbers look like xmas will be dire for hospitals in every affected country13:55
BrainstormNew from r/WorldNews: worldnews: J&J Shot Loses Antibody Protection Against Omicron in Study → https://old.reddit.com/r/worldnews/comments/rgyboq/jj_shot_loses_antibody_protection_against_omicron/14:01
BrainstormNew from COVID on Twitter: UK Prime Minister (@10DowningStreet): Watch this evening's COVID-19 press conference live on our channels from 5pm. pic.twitter.com/H0cDRrueNo → https://twitter.com/10DowningStreet/status/147110295564660326414:11
BrainstormUpdates for Bangladesh: +297 cases (now 1.6 million), +4 deaths (now 28038), +28153 tests (now 11.2 million) since 22 hours ago14:11
BrainstormNew from r/COVID19: COVID19: HKUMed finds Omicron SARS-CoV-2 can infect faster and better than Delta in human bronchus but with less severe infection in lung → https://www.reddit.com/r/COVID19/comments/rgylbk/hkumed_finds_omicron_sarscov2_can_infect_faster/14:21
BrainstormNew from COVID on Twitter: Marc Veldhoen (@Marc_Veld): This is indeed (thanks @mugecevik) like previous observations in @BalazsLab showing Omicron to be quicker. An attribute required although delta is already very quick to get in, multiply, and spread before being cleared by our immune system.medrxiv.org/content/10.110… → https://twitter.com/Marc_Veld/status/147110744349312204814:31
BrainstormUpdates for Switzerland: +11128 cases (now 1.1 million), +26 deaths (now 11888), +78123 tests (now 13.3 million) since 23 hours ago14:36
BrainstormNew from Johnson&Johnson: Johnson & Johnson Announces Positive CHMP Opinion for a Booster Shot of its COVID-19 Vaccine: CHMP recommendation based on data showing a booster (second shot) of the Johnson & Johnson COVID-19 vaccine increased protection to 75 percent [... want %more?] → https://www.jnj.com/johnson-johnson-announces-positive-chmp-opinion-for-a-booster-shot-of-its-covid-19-vaccine14:40
BrainstormNew from EMA: Human medicine assessment reports: (news): Human medicines European public assessment report (EPAR): Comirnaty, Tozinameran,COVID-19 mRNA Vaccine (nucleoside modified), COVID-19 virus infection, Date of authorisation: 21/12/2020, Revision: 17, Status: Authorised → https://www.ema.europa.eu/en/medicines/human/EPAR/comirnaty15:00
BrainstormUpdates for Saudi Arabia: +88 cases (now 550457), +1 deaths (now 8857), +56516 tests (now 32.1 million) since a day ago15:07
BrainstormNew from StatNews: Bowing to pressure, J.P. Morgan says its health care conference will be virtual: The J.P. Morgan Healthcare Conference, biotech’s biggest annual conference, will be virtual, the bank said, bowing to pressure from big-name drug companies [... want %more?] → https://www.statnews.com/2021/12/15/bowing-to-pressure-j-p-morgan-says-its-health-care-conference-will-be-virtual/15:09
BrainstormNew from EMA: What's new: General: COVID-19: latest updates → https://www.ema.europa.eu/en/human-regulatory/overview/public-health-threats/coronavirus-disease-covid-19/covid-19-latest-updates15:29
BrainstormNew from COVID on Twitter: Florian Krammer (@florian_krammer): Davide Corti has some very interesting data for neutralization drop against Omicron that includes Sputnik V and SinoPharm (BBIBP-CorV, inactivated vaccine).  biorxiv.org/content/10.110… pic.twitter.com/p5efr5X26P → https://twitter.com/florian_krammer/status/147112686775953817715:38
BrainstormUpdates for UAE: +148 cases (now 743152), +340100 tests (now 105.6 million) since a day ago15:38
BrainstormNew from NPR: Omicron spreads faster than any other variant, WHO says. It's now in 77 countries: "Omicron is spreading at a rate we have not seen with any previous variant," says WHO director-general Tedros Adhanom Ghebreyesus. → https://www.npr.org/sections/coronavirus-live-updates/2021/12/15/1064432010/omicron-spread-variant-coronavirus15:57
BrainstormNew from COVID on Twitter: John Burn-Murdoch (@jburnmurdoch): We got through bucketfuls of listener questions today, on everything from Omicron’s severity, to impact on kids, to the new paper on bronchi vs lungs, to lateral flows vs PCRs. If you missed it, listen back here: twitter.com/FinancialTimes… → https://twitter.com/jburnmurdoch/status/147113551289121588816:17
rpifanwhen will novavax be ready for europe16:27
rpifanand / or the other one16:27
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): Omicron’s immune evasiveness across all vaccines and prior Covid infectees, now widely replicated for the marked decline in neutralizing antibodies twitter.com/florian_kramme… → https://twitter.com/EricTopol/status/147113710132012237016:27
undefined_bobrpifan: not clear yet16:28
rpifansuchs16:28
rpifansucks16:28
xxyou think it will finally convince some people to vaxx?16:29
xxsome people = some vulnerable groups of people16:29
BrainstormUpdates for Canada: +4635 cases (now 1.9 million), +32 deaths (now 30031) since 23 hours ago16:40
lastshellguys if I have 3 air filters plus house with merv 13 and two fans with merv13 will be safe to host xmas at home for 8 people ?16:46
xxlastshell: in combination with other measures, you are decreasing the chance of infection but not eliminating it16:52
xxyou'd really need an industrial-grade air circulation mechanism instead, that doesn't let any breathed out air reach any other person16:53
xxbasically wind in every room, probably coming from the ceiling into the floor16:53
Guest53_ex_47A bit of moral dilemma here. I was thinking of ending my social isolation today, as it's 10 days from my first positive test. The LFT shows an extremely faint T line. It literally developed at min 25. Even now it's almost an hour and the line is barely visble. Can I safely end self isolation?16:53
ublxxx: from the ceiling onto the floor?16:54
xxublx: if I remember it right, yeah16:54
xxthe alternative would be to severely increase the gravitational force in your house, but the tech is not there yet16:55
ublxno expert on airflow but i wouldn't want to homogenise the indoor air even with all that filtration16:55
xxGuest53_ex_47: it depends on what you mean by ending it. You want to go out and party in a club? Or you want to put on a mask and go shop for necessities?16:55
xxublx: I'm just comparing it to a clean room (not medical) setup we have16:56
BrainstormNew from r/COVID19: COVID19: T-cell vaccines could top up immunity to COVID, as variants loom large → https://www.reddit.com/r/COVID19/comments/rh1wxh/tcell_vaccines_could_top_up_immunity_to_covid_as/16:56
xxclean filtered air coming from high, and getting sucked out near the floor in many places16:57
ublxthe idea being to move contaminants to the ground as quickly as possible? is that a useful principle for an aerosol that follows airflow and doesn't go to ground?16:57
Guest53_ex_47xx just go out and shop. However Friday I have an appointment at the hospital16:57
ublxwhy would the air on the ceiling be clean in a homogenised environment?16:57
xxGuest53_ex_47: that doesn't sound like an ethical dilemma, but I know little about ethics. I know people go out shopping even when positive :\16:58
xxublx: don't know, it's blown by fans16:58
xxsucked in through multiple hepa filters regularly inspected and replaced16:58
xxalso has some weird anti-humidity treatment to it16:59
ublxinspected and replaced during a christmas gathering?16:59
ublxi'm not sure lastshell's system is drawing outdoor air in through these filters16:59
Guest53_ex_47I just want to be sure I'm not infecting anybody16:59
xxGuest53_ex_47: good that you're being considerate, but if you're really concerned then just shop online and order deliveries?17:00
Guest53_ex_47No I'm going mental here17:00
Guest53_ex_47I need to at least have a walk17:00
xxa walk away from anyone else should be fine17:01
ublxGuest53_ex_47: can you wear an N95 mask indefinitely?17:01
Guest53_ex_47no17:01
ublxat all?17:02
Guest53_ex_47how does a no mean anything else than a no?17:04
ublxi took your no to be an answer to my question, which was qualified with the word indefinitely17:04
ublxso in that context, 'at all' means can you wear an N95 for perhaps a short time?17:05
lastshellyes the filters will arrive today17:05
ublxanyway17:05
ublxhow about shop online and do exercise outdoors17:05
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): Congratulations to @Tuliodna and @kallmemeg for their extraordinary efforts during the pandemic, named today as @Nature's 10, among 10 people who helped shape science for 2021 nature.com/articles/d4158… pic.twitter.com/Yd8ukcsxvn → https://twitter.com/EricTopol/status/147114829322887987317:06
Guest53_ex_47well i need to kno if i can end self isolation or not. that faint line might be there forever, although it's fainter evry day17:06
ublxwith government estimating 200,000 cases in the UK right now, and doubling time shortening, why would you want to go inside a busy shop right now17:07
Guest53_ex_47ubix you are missing the point here17:07
ublxthe point being you're going slowly mad being cooped up inside?17:07
Guest53_ex_47no i'm fastly mad17:08
Guest53_ex_47the point is: the rule says 10 days isolation from first symptom17:08
ublxwhat do the instructions that came with the LFT say about very very feint lines?17:09
Guest53_ex_47I've done it. However the LFT is not 100% negative17:09
Guest53_ex_47ubix the instructions are for the first test17:09
Raf[m]I must not be the only one who doesn't care about being quarantined. Plenty to do to keep busy in my house17:09
ublxthe point might become moot when the country runs out of lat flow tests. you're in the UK, right?17:11
ublxRaf[m]: you're not the only one, but safe to say isolation as taken a huge toll on others17:12
Raf[m]True17:14
JigsyNearly 80K cases today in the UK.17:15
xxlastshell: well, at the very least you'll have cleaner air in those rooms, with less dust and fungal spores and other stuff17:15
xxcan't really predict what effect it will have on covid though17:15
BrainstormNew from Reddit (test): CoronavirusUK: Wednesday 15 December 2021 Update → https://old.reddit.com/r/CoronavirusUK/comments/rh2h7h/wednesday_15_december_2021_update/17:16
ublxi stumbled on this thread roll from back in april: https://twitter.com/jljcolorado/status/138356690879705907817:17
ublxseems like a solid gathering of evidence about aerosol transmission17:18
lastshellI hope is enough for 8 humans17:18
ublxit's not exactly the turnkey quantitative analysis lastshell might want, though17:19
lastshellthanks xx ublx17:19
xxhence I'd still say to use it *in combination* with other measures to reduce chance of infection. Any combination of (or preferably all of) tests on the day, handwashing, masks, keeping a distance from each other, no handshakes, ...17:20
xxespecially if older people or vulnerable ones are present17:20
ublxopen all the windows.. hope you live in a warm country17:20
lastshellyeah it will be 4 above 6017:20
xx64°C should be hot enough17:21
BrainstormUpdates for Portugal: +5800 cases (now 1.2 million), +11 deaths (now 18698) since a day ago — Netherlands: +13545 cases (now 3.0 million), +42 deaths (now 20712) since 23 hours ago17:30
ublxtrouble with a christmas gathering is you can't eat wearing a mask. talking, singing, and making merry are aerosol generating events. all that filtration would reduce the viral load in the air but can hardly eliminate it with 8 people talking and making merry in an enclosed space. xmas gatherings aren't 5 minute affairs, are they? this is a risk decision you and your guests must make together.17:32
xxblend all the food and suck it in using a straw?17:33
lastshellall guest are full vaxxed mom and I had booster17:33
xxI'm surprised they haven't started making masks with a straw port17:34
lastshellto be honest we are still thinking if we are going to cancel xmas again17:34
xxlastshell: don't call it "cancel xmas", instead call it "transform xmas" and hold it online or over videocalls or something17:35
xxif that's the decision you end up making17:35
JigsyChristmas is actually cancelled this year.17:35
JigsySanta knew Epstein.17:35
Jigsy</dark>17:35
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): Today the UK had 78,610 new cases, well above any prior day in the pandemic, representing the combined effect of Delta and Omicroncoronavirus.data.gov.uk@OurWorldinData pic.twitter.com/0JBjXaXLW2 → https://twitter.com/EricTopol/status/147115409256307098117:36
xxJigsy: well, someone had to provide the list of naughty kids.....17:36
ublxxx: i was just reading your comments from earlier in the day. you said (paraphrasing) "... reduce healthcare to people who are obese or who smoke ..."17:53
ublxintentionally culling humans is a ridiculous position to take when banning tobacco, banning addition of sugar to savoury foods, banning the use of HFCS, and investigating and regulating the use of certain endocrine disruptors out of existence would achieve a more stable and civilised result17:55
BrainstormNew from ClinicalTrials.gov: (news): Effect of Post Covid-19 Hypoxia on Placenta of Normal Pregnant Women: A Possible Role of Hypoxia Inducible Factor-1α. → https://clinicaltrials.gov/ct2/show/NCT0515886817:55
xxublx: yeah, let me know when they actually ban tobacco, added sugar, HFCS etc.17:56
ublxmaladaptive lifestyle 'choices' are in no small part a consequence of political corruption and profit motive17:57
ublxbut you would preserve that iniquity by sweeping away the victims of it?17:57
ublxi suppose if we want to give you the benefit of the doubt, we could call that a narrowing thoughtlessness17:59
xxI don't believe in equality. Someone who chooses to smoke should not have the same access to lung transplants as someone who does not smoke.18:00
xxsimilarly I don't believe that someone who is vulnerable and chooses to not get the vaccine should get the same access to an ICU bed as someone who did get the vaccine, when triage has to happen18:01
ublxi doubt many committed smokers are offered lung transplant18:01
xxdoctors already play god all the time, it's just swept under the rug in the interest of not causing public outrage18:02
BrainstormNew from ClinicalTrials.gov: (news): Transplantation of Deceased Donors With COVID-19 Into COVID-19 Negative Recipients Utilizing Casirivimab and Imdevimab Antibody Cocktail → https://clinicaltrials.gov/ct2/show/NCT0515799718:05
xxduring med training, it's a typical question, "what do you do when you have a morbidly obese patient and a fit looking patient competing for the same hospital bed", and of course the right answer is that they both deserve the same best kind of treatment that modern medicine can offer, irrelevant of anything else, and that's the only acceptable answer. But you can see it on the doctors faces and18:05
xxthe students do understand it what is actually being said between the lines.18:05
ublxtriage for resources is routine and at least in some places favours maximum benefit. a patient ravished by smoking is already likely to lose to this calculus at the point of triage18:05
ublxdeciding ahead of time to exclude classes of patients is thus needless18:06
xxI'd love to see research being funded into what sort of effect it would have on doctor stress levels and how much more rest they'd get (and thus perform better in general, as well as have much lower ptsd and whatever) if the hospital system wasn't constantly stressed by people who voluntarily destroyed their bodies or severely limited their bodies ability to fight off disease or recover18:09
xxbut nobody will fund that, because such research would not pass any ethics board18:09
xxnobody seems to care just how hard it makes the life of medical personnel that they are overloaded with having to help people who have a lifelong refusal of trying to help themselves18:10
xx"doctor you are my slave, I order you to fix me!"18:11
ublxi don't see what ethics concerns would have to do with comparing the psychological lives of healthcare professionals in hyper urban environments to those practising with lower intensity in more healthful populations, examples of which can surely be found18:12
BrainstormUpdates for United Kingdom: +15421 cases (now 11.0 million), +1410817 tests (now 380.9 million) since 22 hours ago18:14
BrainstormNew from COVID on Twitter: Gunhild Alvik Nyborg (@GANyborg): Brace for impact!Go home, stay home. Reports say omicron doubles every 1.6 days in UK and Delta cases still rising. Let’s get those boosters into those arms. And include the kids! No more talk. Time for action twitter.com/bnodesk/status… → https://twitter.com/GANyborg/status/147116582792377549218:14
xxublx: then you haven't dealt with ethics boards enough, or maybe you were just luckier18:15
ublxthe comparison study you envisage seems eminently achievable to me by questionnaire18:17
ublxnot sure which ethics board would object to that18:18
ublx"... but I have a hunch that if people knew they wouldn't receive any medical care, then they'd take measures ..."18:20
ublxplausible18:20
ublxbut it is not ethical to indoctrinate a population into a consequential belief, then alter the social contract to their detriment or death18:21
ublxfor precisely the reason of your hunch18:21
ublxwhich i suppose is why NZ is attempting to tackle smoking by preventing NEW smokers by banning sale of tobacco to young people going forward18:21
ublxthis sidesteps the ethical crime of downgrading the long standing social contract18:22
BrainstormNew from BBC Health: Covid: UK reports highest daily cases since the pandemic began: A further 78,610 people tested positive for Covid-19, a rise of nearly 20,000 on the day before. → https://www.bbc.co.uk/news/uk-5967315018:24
xxublx: I'm not really in favor of banning things, I am however in favor of "you are free to do this, but expect consequences"18:27
ublxare you in favour of fulfilling contractual obligations, implied or signed?18:27
xxa very broad question where I can't give absolute answers, but I do see what you're getting at18:28
xxok, say that children born from 2 years in the future will only receive the best medical care available if they take care of their own bodies, and every other child would have to pay full price. That's at least a start towards a trend of having a healthy population on this planet that is more resistant to all sorts of diseases.18:30
xxinstead of the current climate where every gov is draggin their feet without implementing any real solution that would endanger their chances of getting reelected18:30
ublxchange child for adult and you might have the beginnings of an argument18:31
ublxchildren are generally not considered capable of being culpable18:31
xxsure, I see your point18:31
lastshellhttps://amp.theatlantic.com/amp/article/621004/18:32
xxeven the parents might however pay more attention to what their kids are eating and whether they are exercising or doing other problematic stuff if they knew that their kids would have to live with the consequences once they reach adulthood18:32
ublxi don't recall the age/number but i think NZ's tobocco measure applies to anyone born after such and such a date, causing it to apply to people passing the age 20 or so right now18:33
xxwhereas right now I'm seeing parents not care as much, because big daddy gov will take care of the kids anyway no matter what18:33
BrainstormNew from COVID on Twitter: Michael Lin, PhD-MD  (@michaelzlin): Above I wrote 3mo as ideal interval in one tweet and 6-mo two tweets later. 3 or 6 mos between RNA shots 2 and 3 elicit similar peak nAbs, based on my skimming of the studies. So anything from 3 to 6 mos would work and timing could be based on when [... want %more?] → https://twitter.com/michaelzlin/status/147116989446071501018:34
ublxbut even so narrow a measure, generalised to all maladaptive behaviours, will condemn a multitude to misery, unless education and poverty-reduction measures precede the change18:34
ublxit's still a sort of genocide, if huge swathes of society cannot obtain foods free of adulterants like HFCS, other pointlessly added sugars, and endocrine disruptors18:35
ublxie you still have to tackle the constitution of society that allows tiny minorities to gather a ludicrous proportion of wealth by purging their entropy into powerless people18:37
BrainstormUpdates for Italy: +23190 cases (now 5.3 million), +129 deaths (now 135178) since a day ago18:38
xxwell, I haven't seen a fat north korean or photos of fat people in famine-stricken areas at any point in history. Not that starving people out is a good way of going about it, but it kinda proves the calories in calories out stuff which I understand better than the psychological issue of affluence of "I'm an adult, there's nothing stopping from buying a birthday cake and eating it all by myself"18:40
ublxa fat north korean: https://upload.wikimedia.org/wikipedia/commons/1/12/Chairman_Kim_Jong_Un_%2848164813552%29.jpg18:41
xxwell, yeah, besides that one18:41
ublxcalories in-calories out is meaningless for malnourished people who can obtain enough calories but not enough nutrients18:43
BrainstormNew from Medical Xpress: UK records highest ever daily number of coronavirus cases: Britain on Wednesday recorded a further 78,610 laboratory-confirmed coronavirus cases, the highest daily total since the pandemic hit the country last year. → https://medicalxpress.com/news/2021-12-uk-highest-daily-coronavirus-cases.html18:43
ublxexcuse me, afk18:43
xxfor 1.8B USD/day I could provide nutritious food for all americans, including all transportation costs etc.18:44
ublxi bet you couldn't18:44
ublxpeople would fight you if you tried18:44
ublxbut please try18:44
ublxreally afk18:45
Arsaneritxx: I also bet you couldn't.  That's a hell of a logistical challenge.18:49
xxArsanerit: for that price, I could even have it delivered straight to the door18:49
Arsaneritxx: that's not the point.  The point is the organisation.18:49
xx2000kcal/day, with all the nutrients, using already existing infrastructure, to 360M americans18:50
ArsaneritDo you have experience in organising the logistics of distributing something reliably to several hundred million people?18:50
xxyeah18:50
ArsaneritYou do?18:50
ArsaneritIn what way?18:50
ArsaneritIf you really belong to the very very few people who do, I might lose my bet.18:50
xxtransatlantic ship stuff18:50
ArsaneritHow can a transatlantic ship distribute anything to several hundred million people?18:51
xxstuff like oats from canada to europe18:51
ArsaneritIt can at best distribute it to a harbour.18:51
ArsaneritThat's not the problem.18:51
xxor flax from china to europe18:51
ArsaneritThe USA does not even have a centralised citizen's registry.18:51
xxor rice to USA18:51
ArsaneritHow are you going to ensure you're getting the food to every last home in cities, prairies, and reservations?  Do you include undocumented migrants?18:51
ArsaneritSending a ship from one harbour to another is easy.18:52
xxideally it would be goop served at whichever is the local gov building, available to whoever asks for it18:52
ArsaneritSending it to a local government building is not the same as sending it to the people.  It means you need the cooperation of the local governments.18:53
xx2 year retention of nutrients, no need to cooling/heating18:53
BrainstormNew from COVID on Twitter: Dr Emma Hodcroft (@firefoxx66): “There’s not much that can spread this fast and be benign to a society that’s already got full hospitals without it.” @BillHanage “I’m not sure the message has gotten across to the decision-makers, how much tougher Omicron is going to make [... want %more?] → https://twitter.com/firefoxx66/status/147117543326161716218:53
xxthere already is massive existing infrastructure for all this18:53
xxeven simpler than vending machines18:53
ArsaneritThere is?  It's not like you can simply call up DHL and ask them to pick up 500,000 parcels from your distribution center every week.  And who packages those parcels?18:54
xxand for those who already have an address, it could simply be sent straight to their home18:55
ArsaneritHow many people will you need to hire to take care of the packaging?  What software will you use to automate the labelling?  How many regional distribution centres will you use?18:55
xxArsanerit: millions of parcels are already delivered every day, and it would be a single 100kg delivery per person per year18:55
xxwe make more fridges than that every year and move them across the world18:56
ArsaneritThere are, but not by you.18:56
xxsimply put, it's doable, but it would destroy the USA food economy18:56
ArsaneritIt's doable, but it needs people with experience in logistics.18:56
ArsaneritOne parcel per year cannot provide reliable quality nutrition.18:57
xxnestle has all the necessary experience already, if one wanted to do it through a private company18:57
ArsaneritYes, there are companies out there that have the necessary experience and infrastructure.18:57
ArsaneritYour claim, however, was that /you/ could do it.18:57
xxArsanerit: sure it can, quality nutrition is easy if you don't care about it tasting good18:57
ArsaneritIf you have several billion, you could quite probably pay a company to do it for you.18:58
xxyes, *I* could literally do it18:58
ArsaneritFood that tastes bad is not quality nutrition.18:58
ArsaneritLiterally do what?18:58
ArsaneritLiterally organise the distribution?  Literally hire people who will organise the distribution?18:58
xxthe organization, I don't have the money18:58
ArsaneritOn your own?  Or leading a team?  How large a team?18:58
xx400 people for the basic stuff18:59
xxthe rest is outsourced18:59
xxand it is still kept within that budget I gave above18:59
ArsaneritThat's 6 USD per person per day.18:59
xxyes18:59
xxat 2000kcal/day19:00
ArsaneritI do suppose it could be done, but the organisation is not easy.19:00
LjLUhm I don't make the rules in Guest's country (the guest formerly known as someone who was in the channel), and if the rule is actually after 10 days from the first test you are allowed to break quarantine, period, without other caveats, then I can't say "you can't", because patently they can. But I would say it's extremely ethically questionable to "go shopping" within 15 days of the first positive test *and when the test is actually still positive*19:00
xxArsanerit: I didn't say it is easy, I am saying that infrastructure and people skills already exist19:01
Arsaneritxx: Yes, the infrastructure and people skills exist, I agree.19:01
xxlike, ok, I have no idea what to do if there's someone in the middle of nevada desert with no access road19:01
xxpeople will always fall through the cracks of any net19:01
ArsaneritBut I'm not convinced you personally could lead that organisation.  Maybe you could, but I don't know.19:02
ArsaneritI certainly couldn't lead such a major operation.19:02
BrainstormNew from COVID19 Vaccine Tracker: valerie: AnGes: AG0301-COVID19 → https://covid19.trackvaccines.org/vaccines/3/19:03
ArsaneritOf course kcal/day is not the only requirement for a healthy diet.19:03
xxit really isn't as major as you might think, there's so much infrastructure in place to make it doable, with so many already knowleageable people already19:03
ArsaneritYes, we have knowledgeable people.19:03
xxArsanerit: with all the RDAs met of course, at 2000kcal/day19:03
ArsaneritI'm not sure if finding knowledgable people and delegating the operation to them counts as "I could do it", though :)19:04
ArsaneritI know such nutitrion mixes exist, that contain a healthy mix of everything a human needs.19:04
ArsaneritI've tried some.  I don't think you'll find many people willing to eat only that for a year.19:05
xxpeople keep comparing this to the failures of food programmes in africa, without realizing that USA has so much more infrastructure to make something like this doable19:05
ArsaneritWhat failures?19:05
ArsaneritFood programmes in Africa save many many lives.19:05
xxmismanagement of money, delays in shipments, border issues, improper storage, fast deterioration of nutritional value, ...19:05
ArsaneritOnly when there is a total breakdown of society in a severe civil war does the famine beat the food distribution programmes.19:05
ArsaneritAnd despite all that, famines really happen only in case of war or extreme government mismanagement.19:06
xxI mean, arguing that something like this is impossible is the same thing as arguing that a vaccine could not be developed in 1 year and distributed to 360M people on a schedule, while keeping it in controlled conditions19:07
ArsaneritI'm not at all arguing it's impossible.19:07
ArsaneritI'm arguing that I'm not convinced that /you personally/ could organise this.19:08
ArsaneritIt's certainly possible.19:08
xxkinda a moot point then19:08
ArsaneritBut I think it needs a team of experienced people to lead it.19:08
xxsure, I have no qualms with that19:08
ArsaneritThe vaccine distribution was probably led by a team of experienced people.19:08
ArsaneritAnd probably didn't go entirely without problems.19:09
xxwell obviously I'm not describing it as me being a dictator shouting out orders to every level of the puzzle19:09
ArsaneritBut 6 USD per person per day?19:10
xxyes, though it is a number from 2013 when I (and a few others) looked into it19:10
xxI still think it is doable at that price point19:10
ArsaneritWould people get a mixed diet including fresh products, or just a powder mix containing "all nutrients" that they would eat every day for a year?  Or something else yet?19:10
xxno fresh products at all19:11
xxliterally a powder mix19:11
ArsaneritPeople won't want to eat that for a year.19:11
ArsaneritI doubt people would call it quality food either, even if it contains all nutrients their body physically needs.19:11
xxboth true points19:11
ArsaneritBut distributing such a powder mix to all for 6$/day, probably it could be done.  I don't think it would be particularly useful to solve any particular problem.19:12
xxbut reassuring to know that if shit hits the fan, USA people won't starve to death19:12
ArsaneritIf shit hits the fan, your distribution network will break down.19:12
xxdepends on the kind of shit I guess19:12
ArsaneritThe kind of shit that may lead to people starving to death.19:12
ArsaneritThat would be very serious shit.19:12
BrainstormNew from COVID19 Vaccine Tracker: valerie: Altimmune Inc: AdCOVID → https://covid19.trackvaccines.org/vaccines/75/19:12
xxsay meat imports from outside of USA stop due to some cattle disease, but grain imports are unaffected19:13
ArsaneritNobody will starve to death due to lack of meat.19:13
ArsaneritHas the USA ever seen a famine in which a substantial number of people died?19:13
xxand yet people think that19:13
ArsaneritPeople are wrong.19:13
xxnot the USA, but the land that USA currently resides on yes19:14
xx(but still after 1500s)19:14
xxnot in any living person's memory I guess19:14
ArsaneritPost-columbian, but pre-USA?  Where was that?  Mexico?  French colonies?  Native tribes driven away by europeans to unproductive land?19:15
ArsaneritI imagine those ethnic cleanings may have led to deadly famines.19:15
ArsaneritI classify that as civil war / severe government mismanagement, though.19:15
LjLI quit smoking around 10 years ago. It was easy, it only took not lighting up a cigarette anymore. And since I could do it, everyone who doesn't must be extremely weak-willed and, while they are much, much more likely than the average person to die or become chronically I'll than the average non-smoker, telling them they'd have to pay to get cured would almost certainly suddenly make them stop craving smokes.19:16
ArsaneritLjL: Is that sarcasm?19:16
Arsaneritbbl, time to cook19:17
LjLBefore I quit smoking, I didn't think of it this way, but since I have hindsight now, I think anyone who doesn't have hindsight in advance must not have much foresight19:17
LjLArsanerit: "no"19:17
Arsanerit"ok"19:17
xx"ha"19:17
xxbut seriously, I only see some people make a meaningful change in their own life once they are forced to face some harsh reality19:18
lastshellI hear civil war is comming19:18
dTalpersonal 👏 responsibility 👏 is 👏 not 👏 public 👏 policy19:19
xxlastshell: unlikely19:19
lastshellmaybe I should stop reading r/collapse19:20
dTalwhen you have a mass problem - a crowd of people going the wrong way, an intersection with many accidents, a public health crisis - the solution is never to say "people should be more careful"19:20
xxdespite all the bad stuff that's happening, on a population level we're all doing much better off than before, and there isn't a significant enough large segment of population that would be willing to potentially lose what they already have19:21
dTalit's fine to say to yourself, "I should be more careful"19:21
LjLxx: yes, theoretically knowing something and practically experiencing does seem to activate some profound bias in humans. However, have you considered that the brain is also a human organ, subject to a variety of hormones and other things that can act quirky, and that while you're taking an extreme "free will" position, one might equally as easily take a "it can't be helped" position? Even when things are meaningfully changed only after a harsh reality loom, that19:21
LjLcould be used as an argument to say people just can't help it, as they knew it rationally from before, but the right neurons only activated when elicited by active danger19:21
LjLSo your position on provision (or payment) of healthcare is arguably akin to saying my liver gets free healthcare but my brain doesn't19:22
BrainstormNew from Politico: Coronavirus: Boris Johnson in coronavirus booster plea as UK logs record cases → https://www.politico.eu/article/boris-johnson-plea-uk-record-daily-coronavirus-numbers/19:22
dTaloh that's extremely well put LjL19:22
xxdTal: but it's not right to imply or even outright say "You don't need to be careful, we'll take care of you"19:22
xxat least in my worldview19:23
dTalbut no one is saying that19:23
LjLI'd have other things to point out too. You say you are against ban but in favor of personal responsibility by "making them face the consequence". You admit ethics is not your forte but I will ask anyway: would it be reasonably, in an extreme, for the government to announce they will deny medical care to new smokers, but at the same time launch (or allow to be launched) a massive marketing campaign, possibly including advanced psychological trickery, that tries to ge19:23
LjLkids to take up smoking?19:23
xxdTal: you really don't get the feeling that that's the message that all the political parties are sending (at least at times)?19:24
dTalno I don't and listen to LjL19:24
LjL[19:22]  xx: dTal: but it's not right to imply or even outright say "You don't need to be careful, we'll take care of you  <-  I think if nothing else, that misses the important fact that smokers or obese people are at markedly heightened risk of death and disability *anyway*, even if the healthcare system does the best it can, just because it's not magical yet. So those people are already facing dsnger19:26
xxLjL: tough question, and the reality of being is that the individual that is prone to be affected will lose every time, so the gov won't be able to effectively stop the marketing anyway (similarly how war on drugs in a losing battle).19:26
LjLWell at least we've moved to a stage in the discussion where this are tough questions, which I will take as an improvement :p19:27
xxI mean, it is a tough question, but it still can be answered19:27
dTalwhat it boils down to is that making people face personal consequences by witholding social services is a) cruel, and b) ineffective19:28
dTalyou wouldn't raise a child that way19:29
xxI'm not concerned about 'a)', and I'm not sure about 'b)' because it hasn't been tried19:29
dTalyou're not concerned about amplifying human suffering?19:30
LjLxx, your answer then being "since the reality is that those individuals will lose anyway, the answer is that i don't care and as society we should not care or even be particularly harsh on them"?19:30
dTalI am curious what exactly are your terminal values then, since you're happy for humans to go away and you're happy for them to suffer while they do so19:30
xxLjL: I'm saying we can't save everyone, and that should mean that we *shouldn't* try to save everyone, especially at a great cost to everyone else.19:30
dTalright now you're presenting yourself as an implacable enemy to humankind19:31
xxI've been called worse I guess19:31
dTalsee there it is again. what could possibly be worse?19:32
dTalwhat do you value?19:32
BrainstormNew from COVID19 Vaccine Tracker: valerie: Aivita Biomedical Inc: AV-COVID-19 → https://covid19.trackvaccines.org/vaccines/74/19:32
xxI don't know, I don't really concern myself with what I value. Guess I like free access to information to everyone.19:33
xxand I like to live in a world that permits such information to be scrutinized and questioned19:33
LjLone of the leitmotifs i'm saying: <x> I'm confused, what would this mean to you? <xx> I don't concern myself with meaning. - it's like you make some bold claims that people are likely to find bad, evil, unethical, and all those sorts of thing, but you think you can skirt it by just saying you don't concern yourself with all those very things that are the big problems with your views.19:34
LjLi'm seeing*19:35
xxwell what I mean by that is that *I* don't matter19:36
dTalif you don't even have values, then how can anyone trust anything about you?19:37
xxI probably have some values, but it's not like I live on some path to spread those values or anything19:37
xxI'm not dedicated to anything is what I'm saying19:37
dTalThat's truly frightening. You advance all sorts of horrible things but you can't even articulate *why*19:37
dTaland now you say you're not even dedicated to anything. what are you? what are you for?19:38
xxffs I'm not trying to intentionally genocide the world population just because it would be fun or anything19:38
dTalwell I should hope not19:38
dTalbut it would be rather more reassuring if you could articulate why that's, you know, bad19:39
dTalespecially since cruelty is apparently fine19:39
dTalwe need to have some common ground in values to even begin a conversation about what we "should" do19:40
xxto say that humans are not extremely cruel species on a population/civilization level would be a lie in my opinion19:40
dTalis that *good*?19:40
dTalyou can't get an "ought" from an "is"19:41
BrainstormUpdates for Germany: +38973 cases (now 6.6 million) since 23 hours ago — Canada: +4560 cases (now 1.9 million), +29 deaths (now 30035) since 23 hours ago19:41
xxit means cruelty is something innate to humans, and can hardly be removed from human decision-making on large (massive) scales19:41
dTalif you say that we should take a particular measure, say for public health.... why?19:41
dTalto accomplish what?19:41
dTaldo you see what I'm driving at?19:42
dTalyou have to have values, that's a prerequisite for any conversation of this kind19:42
xxyes, I do, and I don't particularly wish to bring it up in this channel since it is a bit offtopic, but in the spirit of vhemt maybe humans shouldn't receive any medical care ever19:42
xxbut that's a hard argument to argue19:42
dTalif you say you have none... well go away and come back when you do19:42
xx"you're born into this world, go out and have fun, if you die, you die"19:43
dTalI'd rather you argue that, philosophically challenging as I find it, than argue from a position of nothing at all19:43
dTalmost people have values like "suffering is bad", "humans should not go extinct", "children need protection" etc, in some order of priority19:46
xxguess I differ from those values a lot if I'm for vhemt19:47
dTalI don't find vhemt a coherent concept19:47
dTalit's like advocating for "spontaneous ecosystem self-repair"19:48
dTalhumans will not voluntarily go extinct, it's fundamentally abhorrent to most19:48
xxit's fundamentally abhorrent to most to get qtips stuck in the nose/butt, yet we do that many many millions of times a day19:53
xxhumans are able to do really abhorrent things19:53
xxon massive scales too19:53
spokojni[m]We are all going to die peacefully, from massive heart or brain stroke. Don't worry guys, you won't even know it.19:59
xxspokojni[m]: brain aneurysm can happen at any time to anyone irrelevant of any other factor. Sleep well :)20:00
spokojni[m]I do20:00
xxso do I20:00
spokojni[m]Thanks to Pfizer's Zoloft, not a care in a world man.20:00
xxzoloft is which one?20:00
xxgeneric prozac?20:00
spokojni[m]It's mind altering substance20:00
spokojni[m]Like prozac but newer, better, stronger20:00
lastshellwell we are going to die regadless20:01
xxI see, a 2nd (3rd?) gen one20:01
spokojni[m]Been on it for 2 years now, life's never been better tbh20:01
lastshellbut be positive and enjoy life20:01
xxI've heard good stuff about sertraline, wonder if it has any effect on covid20:01
BrainstormNew from Gazzetta Ufficiale italiana: MINISTERO DELLA SALUTE - ORDINANZA 14 dicembre 2021: Ulteriori misure  urgenti  in  materia  di  contenimento  e  gestionedell'emergenza epidemiologica da COVID-19. (21A07442) → http://www.gazzettaufficiale.it/eli/id/2021/12/15/21A07442/SG20:01
spokojni[m]I've seen some studies, there are few articles, look it up20:01
spokojni[m]And I am vaxxed and untested thanks to Pfizer, If I were not on Zoloft I would probably get vaxxed20:02
xxwell, guess if someone has a positive outlook on life in general, it can lead to positive outcomes of covid, rather than if one just gives up20:02
xxfun stuff indeed https://www.thelancet.com/journals/langlo/article/PIIS2214-109X(21)00448-4/fulltext20:04
LjLspokojni[m], you are unvaccinated (i know that's what you meant since you said it before) "because of taking Zoloft"?20:04
xxthough I imagine the standard issue still applies - the first thing that psychodrugs fix is lack of willpower, which might be the thing that actually gives the person enough will to commit suicie20:05
spokojni[m]Yeah, I don't care about covid, it's just too much birocracy for me and insisting on something that I don't want to take.20:05
BrainstormUpdates for Algeria: +245 cases (now 213533), +10 deaths (now 6165) since 21 hours ago — Morocco: +221 cases (now 951984), +12349 tests (now 10.6 million) since 23 hours ago20:06
lastshellthe democratic hoax :P20:06
LjLspokojni[m], and that has to do with Zoloft, what?20:06
spokojni[m]Yeah I was very anxious person before Zoloft, it changed my personality to what I prefer now.20:07
lastshellexercise do the same thing that Zolof IMHO20:07
spokojni[m]I would probably have some health anxiety and it would be easier to get me persuaded to get vaccinated20:07
spokojni[m]lastshell maybe a little bit20:08
LjLspokojni[m], but getting the vaccine still gives you anxiety about its effects on your health? or why else not take it?20:09
xxyou could get another stamp for your pfizer loyalty card if you get a vax from them :)20:09
lastshellxx XD20:09
spokojni[m]It doens't give me anxiety, I can't be arsed with birocracy and insisting to get it is annoying me.20:09
dTalbureaucracy20:10
spokojni[m]Yeah20:10
dTalbirocracy is rule by ballpoint pens20:10
dTal...oddly, actually something of a synonym for bureaucracy20:11
BrainstormNew from COVID on Twitter: Tulio de Oliveira (@Tuliodna): Obrigado, um dos meus segredos é que trabalho com epidémias com FioCruz e Ministério da Saúde do Brasil (Zika, Dengue, Chikungunya, Febre Amarela) então estavámos bem treinados pra responder pra COVID. A diferença da Àfrica do Sul pro Brasil é que [... want %more?] → https://twitter.com/Tuliodna/status/147119447288095130220:11
spokojni[m]Basically I don't listen to politicians medical advices.20:11
xxdTal: I spell beauty as biuti :p20:12
dTalwell that just confirms my accumulated opinion of you as a lawless agent of chaos :p20:12
xxheh20:12
xxreading that SSRI thing, I wonder if an elevated level of serotonin in cells would have something to do with mitigating the cytokine storm at the very least20:15
xxcells lining the lungs in general don't have much of it, so any noticeable increase could have large effects20:16
xxI've read about some of the cocktail mixes some hospitals give to patients almost in desperation, so it would not surprise me if this was a component in some hospital somewhere20:17
xxactually yeah, various psychoactive substances are routinely administered in the most severe cases20:19
LjLi'd like to see some discussion about that SSRI study but i've only found some not-very-interesting Reddit bantering on r/askscience when i googled it20:22
xxthere are a few weird bits in it, but that's probably because I haven't seen other similar stuff elsewhere20:22
xx"84 participants stopped fluvoxamine and 64 participants stopped placebo owing to issues of tolerability"20:22
xxnot tolerating placebo at that level?20:23
xxthat must just be an effect of not liking pills in general, would be my reaction20:23
LjLwell, they're patients who *have COVID* anyway20:23
LjLyou're not just giving the SSRI to someone with, say, mild depression20:23
LjLso i guess they may easily attribute some symptoms of COVID to whatever they're being given20:24
dTalthat's why we give placebos20:26
dTalthat's not weird, that's literally what they're for20:26
xxdTal: I mean that having 64 out of 1500 participant had to cease taking the placebo feels like a weirdly high number20:28
xxbut yeah, that might just have to do with having covid already, which definitely affects this20:28
dTal"I feel like shit and that pill ain't helping, stop giving it to me"20:29
dTalbut sure, it's intruiging to consider20:30
xxI don't have the number I'm mentally comparing it to, but for cancer patients there is proportionally much lower number of people asking to be taken off placebo20:30
BrainstormUpdates for Djibouti: +12 cases (now 13526), +620 tests (now 252017) since 3 days ago20:30
xxthough I guess it's all to do with just not having high enough numbers in the study, as always20:31
LjLi do think it seems like a high dropout rate compared to "the average study" but i also don't quite have average numbers in mind20:33
xxbrazil is the most populous country of the countries with the highest number of deaths/1M pop, so it also might have something to do with it20:35
BrainstormNew from r/WorldNews: worldnews: Omicron found to grow 70 times faster than Delta in bronchial tissue → https://old.reddit.com/r/worldnews/comments/rh73lx/omicron_found_to_grow_70_times_faster_than_delta/20:40
LjLoh, i was about to post that *deletes message*20:41
LjLi'll post this comment from it then instead https://www.reddit.com/r/worldnews/comments/rh73lx/omicron_found_to_grow_70_times_faster_than_delta/hoomf72/20:41
LjLoh lord, just when you think the guardian article linked to by reddit linked to the actual study, nope, turns out it links about further (though more first-party) news on the study https://www.med.hku.hk/en/news/press/20211215-omicron-sars-cov-2-infection which doesn't link to the study20:43
xxbronchial tissue? Is that one even less accessible to the immune system than lung tissue?20:43
sdfgsdfghttps://www.abc.net.au/news/2021-12-16/omicron-spread-leads-to-uk-record-78000-covid-cases/10070422220:46
sdfgsdfg.title20:46
Brainstormsdfgsdfg: From www.abc.net.au: Omicron spread leads to UK record of 78,610 COVID-19 cases in single day - ABC News20:46
* sdfgsdfg screams like homer simpson20:46
sdfgsdfgsydney's premier daddy perrotett was begging the media to shift the focus from cases to ICU details20:47
xxinteresting how UK is so much higher than other countries20:48
xx2x or 3x the next one?20:49
LjLnews from the future!20:49
xxLjL: you think we'll shortly see a similar rise everywhere?20:50
xxlike, to such high numbers?20:50
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): Another new study shows "decrease in vaccine effectiveness accelerated after month 4 after full vaccination" in US Veterans, age 65+, due to both time of waning and rise of Delta @JAMANetworkOpen  jamanetwork.com/journals/jaman… US policy to change to boost at [... want %more?] → https://twitter.com/EricTopol/status/147120458205104128020:50
ublxmore likely we'll shortly reveal a similar rise everywhere20:51
ublxsdfgsdfg: 'daddy perrotett'?20:51
ublxdidn't we talk about this?20:51
sdfgsdfgthats what some media lady was calling him probably because he has more than 6 kids20:51
xxpity we still don't have good enough data reporting to split the graphs for every country on vaxxed/unvaxxed, maybe with parameters such as number of doses and timings20:55
xxinstead it's still something that needs to be hunted down on the regional country websites, and even then only some countries have that data publicly available20:55
BrainstormUpdates for Spain: +27140 cases (now 5.4 million), +77 deaths (now 88619) since a day ago — Cabo Verde: +18 cases (now 38527) since 23 hours ago21:02
LjLxx, i think so, yes21:09
LjLnot sure how shortly21:09
xxwhat I wish for xmas is for people to finally kicking the habit of licking handrails and doorknobs21:19
xx*kick21:19
ArsaneritWhen can I responsibly travel across the Atlantic Ocean by freighter, from a pandemic point of view?21:20
xxArsanerit: if you're willing to get in a box I can get you on the next boat21:24
Arsaneritxx: I'm willing to get into a cabin booked via https://www.langsamreisen.de/frachtschiffreisen/europa-nord-mittelamerika/deutschland-frankreich-usa/ , but it feels irresponsible and egoistical to do so during the coronavirus pandemic.21:24
dTalxx: I advocate guerilla application of dish soap to all public surfaces21:26
dTalit kills covid, tastes vile, and is non toxic!21:27
xx"ewwwww, that's soap, I haven't touched that stuff since kindergarten" would be most people's reaction based on what I've seen them do about personal hygiene21:27
xxit tastes fine, just can lead to mouth ulcers if you chew on it too often21:28
BrainstormNew from r/Science: science: A study of the impact of national face mask laws on Covid-19 mortality in 44 countries with a combined population of nearly a billion people found that—over time—the increase in Covid-19 related deaths was significantly slower in countries [... want %more?] → https://old.reddit.com/r/science/comments/rh7wdv/a_study_of_the_impact_of_national_face_mask_laws/21:29
BrainstormUpdates for France: +65714 cases (now 8.5 million), +151 deaths (now 121968) since 20 hours ago — Dem. Rep. Congo: +2081 cases (now 61932) since 4 days ago — Eswatini: +1469 cases (now 56200), +1768 tests (now 408820) since 23 hours ago — Burundi: +257 cases (now 21143) since 2 days ago21:39
BrainstormNew from r/WorldNews: worldnews: Facing new COVID wave, staff at a French hospital say: 'We're exhausted' → https://old.reddit.com/r/worldnews/comments/rh8a6v/facing_new_covid_wave_staff_at_a_french_hospital/21:39
xxLjL: I guess this is how shortly...21:41
LjLxx, France has terrible data though21:45
LjLhave the raw, unsmoothed experience http://offloop.net/covid19/?default=United%20Kingdom;France;Spain;Italy;Sweden&cumulative=no&leftTrim=600&legacy=no21:45
LjLwe have weekly trends. they have weekly *binary* trends21:45
xxthanks, looks like EU can't even agree on a unified reporting style for each constituent country21:46
LjLas if the EU works by agreement!21:46
ArsaneritWhy would the EU agree on something that is not a EU responsibility?21:47
xxfeels like something that would be in the interest of every EU citizen21:47
xxbut I guess that's not the job of the EU anymore21:47
LjLthe EU has specific areas of responsibility though, it isn't just the decider of "anything useful"21:48
LjLbut anyway it's not like US data are any better if you look at various member states21:48
BrainstormNew from Virology.ws: TWiV 841: Unmasking immunity: TWiV provides an update on immunity to Omicron, results of a randomized controlled trial of face masks, and a study of correlates of protection against respiratory syncytial virus infection in the upper and lower respiratory tract of nonhuman primates. Click [... want %more?] → https://www.virology.ws/2021/12/15/twiv-841-unmasking-immunity/21:49
ArsaneritThere are also useful things that I could do but that I don't do.21:50
BrainstormUpdates for Kenya: +799 cases (now 257614), +1 deaths (now 5350), +7529 tests (now 2.9 million) since a day ago — Kuwait: +57 cases (now 413847), +19155 tests (now 5.6 million) since 22 hours ago22:04
BrainstormNew from CIDRAP: COVID mRNA vaccines lose strength against Delta over time: Mary Van Beusekom | News Writer | CIDRAP News Dec 15, 2021 One study finds that 2 doses of Moderna were highly effective against all variants, but Delta protection waned. → https://www.cidrap.umn.edu/news-perspective/2021/12/covid-mrna-vaccines-lose-strength-against-delta-over-time22:08
LjLBrainstorm, uh no shit?22:12
xxdid Brainstorm do something wrong?22:12
Arsaneritstating the obvious?22:15
LjLyeah it's just a bit of obvious although it appears they looked very specifically into which variants did what22:16
LjLexclusively with Moderna22:16
LjLand i guess the fact that "Waning was less pronounced for non-delta variants" had not been something that was explicitly stated before22:17
BrainstormNew from COVID on Twitter: Michael Lin, PhD-MD  (@michaelzlin): NYTimes shows the CDC made an error they should have checked for in their COVID19 test design (primers that prime off each other). A competent grad student or postdoc would have noticed. You don't need CDC training, just good experimental [... want %more?] → https://twitter.com/michaelzlin/status/147122709327492300922:17
LjLit was, you know, quite likely, given *we need a goddam multivalent vaccine* and can't just keep using the same one in the fact of a ton of changing variants22:17
LjLbut i guess it's good they actually looked and confirmed it22:17
Arsaneritwhen will get a multivalent vaccine?22:18
xxprobably when we get the one that's using a weakened coronavirus22:21
LjLArsanerit, i don't know, both Moderna and BioNTech/Pfizer (groan) have been working on them for many months now22:23
Arsaneritwhy groan?22:23
LjLModerna has a Beta vaccine under trial, and Pfizer should have a Delta one22:23
LjLnevermind the groan22:23
ArsaneritDoes Beta still exist?22:23
LjLi don't really know when those trials are slated to end22:23
LjLBeta has probably been swamped out by Omicron in South Africa now22:23
ArsaneritAre those trials too slow to be of any use?22:23
LjLbut it doesn't really matter22:23
LjLthe variants tend to have many of the same mutations, in different mixes22:23
ArsaneritWould a delta vaccine be any better than the original vaccine when omicron dominates?22:23
LjLa multivalent vaccine would probably help a lot even if it isn't against the *current* variant, which would be... impossible, anyway22:24
LjLi do think so22:24
dTalOmicron should make us rethink the strategy of chasing variants22:33
dTalthis variant is an offshoot of an early lineage - a delta-specific vaccine would be *less* effective than the one targeting OG covid22:34
BrainstormUpdates for Germany: +55533 cases (now 6.7 million), +511 deaths (now 107675) since 23 hours ago — India: +6265 cases (now 34.7 million), +326 deaths (now 476214) since 22 hours ago — Canada: +5619 cases (now 1.9 million), +23 deaths (now 30037) since 23 hours ago — Netherlands: +13531 cases (now 3.0 million) since 20 hours ago22:35
dTalit sure would be nice to encode *all* extant variants into a vaccine22:35
dTalbut if you have to pick just one - original covid is a good one22:35
xxwouldn't SARS/MERS or the other coronaviruses be decent too perhaps?22:36
xxif it targetted whatever is common to all coronaviruses22:36
BrainstormNew from Politico: Live blog: European Council summit: Fears of new war in Ukraine and a resurgent coronavirus are front of mind as EU leaders gather in Brussels. → https://www.politico.eu/article/live-blog-european-council-eu-summit-ukraine-coronavirus-defense-energy/22:36
xxwait what? new war in ukraine?22:37
dTalhttps://unchartedterritories.tomaspueyo.com/p/the-omicron-question22:39
dTaljust look at those graphs22:39
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): A new report on Omicron's potency for inhibiting vaccine-induced, infection-induced, and monoclonal Ab (mAb) mediated virus neutralization. Only Sotrovimab was effective as a mAb) medrxiv.org/content/10.110… pic.twitter.com/ZeELwqvNbR → https://twitter.com/EricTopol/status/147123325113390284822:46
BrainstormUpdates for Malawi: +318 cases (now 62933) since 21 hours ago — Monaco: +63 cases (now 4223) since 23 hours ago — Bahrain: +53 cases (now 278202), +49580 tests (now 7.7 million) since 23 hours ago — Curacao: +39 cases (now 17657), +1 deaths (now 183) since 20 hours ago23:00
lastshelldTal those are scary graphs23:01
darsiethird shot now after 5 months or wait another month?23:02
lastshelltake the shot darsie (I'm not a medial advisor)23:02
darsiemedial?23:02
lastshell*medical23:03
darsieok23:03
lastshellbut I know people in uk taking the booster before 6 months23:03
lastshellbecause bojo pushing23:03
darsieI'm in Austria. Lockdown, high numbers going down.23:03
lastshelldarise you guys have omicron ?23:04
darsieBicycle grocery delivery.23:04
darsienot much, yet.23:04
lastshellI guess is safe to wait until 6 months23:04
darsiek23:04
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): The North American @Novavax vaccine randomized, placebo-controlled trial in ~30,000 participants is published in @NEJM today with 90% efficacy vs symptomatic infections nejm.org/doi/full/10.10…(most breakthroughs were Alpha; trial predated Delta, Omicron) [... want %more?] → https://twitter.com/EricTopol/status/147123864326415155323:05
dTaldarsie: I would say grab that booster23:10
darsieok :)23:10
dTalomicron is growing *very* quickly23:10
darsiemhm23:11
darsieI live in a 6 ppl shared flat.23:11
dTaloof23:11
dTalmake them all get the booster lol23:11
lastshellwith booster you protect 70% againt's omicron23:13
darsieIs it a bad idea to get it just before an 8h grocery bicycle delivery tour?23:14
dTalon the basis of how I'm feeling right now, yes23:14
darsiek23:14
dTalyou're gonna want to take it easy for a day or two23:14
dTalbut it's a booster, you've had two jabs already I assume?23:15
darsieyeah23:15
darsie2x Moderna23:15
dTalreactions?23:15
darsieI don't remember well :).23:16
darsieThere was something, yes.23:16
darsienot wild23:16
lastshelldTal what is your take about vaccines targeting variants ?23:17
minthosdarsie: maybe plan for a slower than usual pace23:24
darsieI'll get it after my delivery shift.23:25
minthoscool23:25
darsieDon't want to lag behind and get stress.23:26
dTallastshell: what about it?23:27
lastshelldTal you thing if covid continues will be wise to target more agressive variants ?23:28
minthosthey already are, they estimate about 100 days to update the vaccine for a new variant23:30
minthosof course manufacturing and distribution is another issue entirely23:31
LjLdTal: extremely interesting article overall, but I just reached "There’s also another wild card here. Long COVID affects about 2-3% of those infected with COVID" and I'm like, wut, wasn't that much higher by any account?23:33
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): Covid vaccines should be digital: no need to purify proteins, inactivate the virus; just deliver the digital codescience.org/doi/10.1126/sc… @ScienceTM pic.twitter.com/50e1b57qTB → https://twitter.com/EricTopol/status/147124488945097523623:33
LjLTopol going de-facto23:38
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): Yes, a universal coronavirus vaccine is urgently neededToday @NEJM. We can and must do this. nejm.org/doi/full/10.10… Variant-proof, cover all sarbecoviruses ++ twitter.com/EricTopol/stat… pic.twitter.com/IkTT66ANxj → https://twitter.com/EricTopol/status/147124673077971353623:43
LjLWell I shouldn't have read that guy's article linked from the  long covid claim23:49
BrainstormNew from COVID on Twitter: Marc Veldhoen (@Marc_Veld): The 2020s saw the introduction of the coded vaccines; Vaccine delivery no longer depends on making an attenuated virus or production of dead-virus and trying best adjuvant combinations.science.org/doi/10.1126/sc… → https://twitter.com/Marc_Veld/status/147125084329081651723:52
dTalwhy?23:57
dTalscary?23:58

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