libera/##covid-19/ Thursday, 2022-01-06

BrainstormNew from r/WorldNews: worldnews: Tennis star Novak Djokovic denied entry into Australia, visa canceled amid vaccine exemption furor → https://old.reddit.com/r/worldnews/comments/rwz14q/tennis_star_novak_djokovic_denied_entry_into/00:02
BrainstormUpdates for Brazil: +9089 cases (now 22.3 million), +29 deaths (now 619547) since 2 hours ago — Aruba: +1162 cases (now 24210) since 2 hours ago00:06
BrainstormNew from r/COVID19: COVID19: Fully Vaccinated and Boosted Patients Requiring Hospitalization for COVID-19: an Observational Cohort Analysis → https://www.reddit.com/r/COVID19/comments/rwz2i4/fully_vaccinated_and_boosted_patients_requiring/00:12
BrainstormNew from Nature Vaccines: Masaru Shimada et al.: Biodistribution and immunity of adenovirus 5/35 and modified vaccinia Ankara vector vaccines against human immunodeficiency virus 1 clade C → https://www.nature.com/articles/s41434-021-00308-z00:22
sdfgsdfgthe second last study says although the vaxxed DO appear in hospitals and ICUs they have less severe outcomes despite appearing to be higher risk at baseline when compared to unvaccinated individuals during the same time period01:01
sdfgsdfgwho said they appeared to be higher risk at baseline... hmmm01:01
sdfgsdfgcompared to the unvaccinated individuals I mean01:01
sdfgsdfgweird01:01
BrainstormUpdates for Argentina: +95159 cases (now 5.9 million), +52 deaths (now 117346), +325492 tests (now 28.6 million, 0.0% positive) since 3 hours ago — Colombia: +16259 cases (now 5.2 million), +40 deaths (now 130140), +167845 tests (now 30.0 million, 0.0% positive) since 3 hours ago — Tanzania: +1258 cases (now 30564), +3 deaths (now 740) since 3 hours ago [... want %more?]01:02
Tuvixsdfgsdfg: The title in your prior post rather hinted that, but again, it's basically a misrepresentation of the facts. The unvaccinated who contract COVID have had and *continue* to have, in aggregate, signifcantly worse outcomes.01:05
TuvixYou don't want to be unvaccinated and contract COVID, and give how fast and easily this latest varient spreads, it's going to eventually find everyone who doesn't have the luxury of living in a figurative medical bubble.01:07
Tuvixgiven*01:07
TimvdeTuvix: reports are that omicron is less dangerous, and I very much hope that to be true01:09
TimvdeBut just to be sure, I'm going to sit out this wave :P01:10
TimvdeI have ~ no plans for the next month01:10
TuvixSimple math for you: let's create 2 hypothetical idental cities in perfect isolation from the outside world; one has 1/3 vaccinated 2/3 not, the other 2/3 vax'd, 1/3 not. If the same groups are exposed, we'd expect to see twice the number of vaccinated in hospitals in the more-vaccinated city vs. the less-vaccinated, and half the number of unvaccinated. But critically, we'll see *fewer* in the01:11
Tuvixhospital/ICU, and *fewer* dead. That's the importance of vaccines.01:11
Tuvixidentical*01:11
TuvixTimvde: And yea, it seems to be in the average case, but the flip side is some doctors being interviewed are indicating that in the unvaccinated, hospital outocmes tend to be worse, while the vaccinated have better odds of recovery and shorter hospital stays.01:19
TimvdeTuvix: obviously, I'm a big proponent of vaccines (I just got my own booster last week)01:20
TuvixTo be clear, more mild is indeed better than the other options (the same or worse severity across the board) but I fear many places, including here in the US, are going to see hospital cases spike and possibly result in near-term stress worse than we saw back before vaccines were widely available. A largely *avoidable* peak at that.01:20
TimvdeHow is vaccination rate in the US nowadays?01:22
TuvixIt varies a lot by state, but using JHU's high-level data (https://coronavirus.jhu.edu/vaccines/us-states) it ranges from 47.5% of population in Wyoming to 77.7% of pop. in Vermont.01:23
TimvdeOf total population?01:24
TimvdeBecause then 77.7% is pretty good01:24
TuvixOf total pop., yea, and the under-5's still aren't eligible. But the younger agegroups are also under-vaccinated, with something like under 1 in 3 vaccinated in the 5 to 12 year old range nationally.01:25
TimvdeWhere I live, we're at 81% for the region, 76% or the total country, but a big remark is that we only barely started with 5-11 (< 10%, but climbing)01:26
Timvde18+ is 93%/88% for region/country01:26
TimvdeWe got a much more manageable delta outbreak because of that01:27
TimvdeSo if omicron is less bad, I hope the peak will not be much worse than what we got for delta01:27
TuvixWith high vaccination rates, that may well be the key factor in at least not overloading hospitals and healthcare systems.01:28
TuvixIt's so bad in parts of the US that entire regions are warning of degraded emergency response to other, non-COVID conditions. Some places have seen increases in emergency medical response times as well, though that's a regional effect based on when surges hit and how close to capacity the system is before that happens.01:29
BrainstormNew from r/Coronavirus: Coronavirus: Testing Site Says It Detected First LA Flurona Case → https://old.reddit.com/r/Coronavirus/comments/rx0t7t/testing_site_says_it_detected_first_la_flurona/01:29
TimvdeWe're mostly hit by hospital personnel having to go into quarantine, when it comes to impact on care01:30
TimvdeSo... they've lessened the quarantine rules :/01:30
TimvdeNo more quarantine for high risk contacts if you're vaccinated01:30
TimvdeOnly when you develop symptoms01:30
TimvdeI somehow don't think that's a good idea01:31
TuvixHospital shortage is a big deal here too; they're brining in national guard (a branch of the military often used as a reserve for both domestic and foreign needs when additional support is required.) They've sent national and state military medical personell to a number of states with similar staffing issues as you mentioned.01:32
TuvixThe guidance for non-healtcare worker keeps changing and is really not clearly stated. It's all predicated on "suggestions" and what you "should" do, with no requirements, or penalties for say going out in public around other people after testing positive.01:33
TimvdeWe had penalties in the beginning, but they're long gone01:35
TimvdeNow it's basically "You should probably not meet with more than 15 people at once, but who are we to tell you what to do"01:36
TimvdeAnd *still* people are calling it fascist, lol01:36
TuvixThe locality just north of me has similar guidance on their webpage, which I bet most of the people gathering don't bother to read. It's 30 or less people suggested here for indoor gatherings, which is stilly crazy given the spread of omicron, especially in indoor settings here where it's winter and most people don't bring in fresh air at all.01:37
TuvixNot that a single window is really going to change things if everyone is unmaksed anyway, and/or not tested…01:37
BrainstormNew from Ars Technica: Science: CDC muddles message on rapid tests while defending controversial guidance → https://arstechnica.com/01:39
TimvdeI generally try to only see like 3 people at once, and make sure I am tested before01:39
TimvdeI don't generally ask of others to be tested, I don't want to open that discussion01:40
TuvixAnd, right on cue, Brainstorm mentions the confusing guidance here coming out of our top public health agency.01:40
TuvixNot like guidance is all that more helpful at the local levels. From the last weekly update here on the push to keep children in schools for in-person learning, it's all still just suggestions:01:40
Tuvix"Parents and guardians are encouraged to get their children vaccinated and boosted against COVID-19, make sure your child wears a well-fitting mask in public indoor spaces (including schools) even if not required, get your child tested for COVID-19 if experiencing symptoms or exposed to COVID-19, and keep your child home if they test positive or need to quarantine after exposure."01:41
TuvixLangauge like "encouraged" and "if not required" are about as weak as you can get. Some school districts are introducing vaccination requirements, although many of those have broad exemptions you can apply for, so the effect on the currently-unvaccinated is very unclear.01:42
TuvixTimvde: It sounds like many of your locality's guidance is similarly weak, trying to encourage rather than require the yet-unvaccinated.01:42
TimvdeIt is, although they're discussing getting stricter and more concrete again01:43
sdfgsdfgI can't wait to find out if the numbers are going to remain high or everything is suddenly going to end like in SA01:46
sdfgsdfgit'll be a fairytale of a wave apparently :P01:46
sdfgsdfgor a biblical plateau01:47
Tuvixsdfgsdfg: ICU capacity in my region went back to 100% of ICU beds in this entier corner of the state reporting peak capacity. You do not get an ICU bed here until someone either recovers enough to be moved out, or dies.01:47
TuvixCar crash? Heart attack? You won't have a bed, not in the ICU anyway, when you arrive.01:48
TuvixAnd Omicron hasn't really even hit here yet, as of the Dec-31 update; only about 50% of sequenced cases are Omicron, though that's obviously rising.01:48
sdfgsdfgoofff.. you guys couldn't afford another week added on top of this01:48
sdfgsdfganother week of increase*01:48
TuvixOur system is in bad shape now, and it's going to get worse with the vaccination rates. Statewide we're also seeing a rise in hospitalizations, though this region of the staet saw a slight decrease in overall hospital capacity (but not the ICUs.) The wave is presumably coming in the next 1 to 4 weeks here.01:49
sdfgsdfgIt doesn't sound like delta is being suppressed01:50
sdfgsdfgI thought it was, in UK. This is so confusing =/01:50
TuvixIt is in areas where the wave hit earlier; it just spreads unevenly across the US due to geographic differences, but it's taken hold pretty much everywhere once given some time to spread.01:50
TimvdeTuvix: our ICU beds *at full capacity* are about 1/3 full01:51
TuvixMost of New England on the northeastern seaboard is 95% or more Omicron now.01:51
TimvdeIt's just that the capacity dramatically lowered01:51
sdfgsdfghere in Melbourne I recently noticed the news about 40% delta still being in criculation01:51
Timvde(We still have a decent amount of wiggle room though, if you're in a car crash tomorrow, you definitely get an ICU bed if you need it)01:51
TuvixTimvde: Ah, due to staffing I take it? The numbers on this state-level summary for this region indicate 93.6% ICU beds in use, but 100% of reporting hospitals state they're running ICUs at "peak capacity" which I presume meands some beds are not staffed, thus useless.01:51
Tuvixmeans*01:52
TimvdeBut the omicron wave just started to rise, and with it the hospital admissions, so we'll see01:52
TuvixRight, I mean, the hospital won't refuse to take you, but you may be kept in a hallway or other packed room until you can get a proper recovery area.01:52
TimvdeI mean: you will get the care you need... for now01:52
TuvixThe problem with a 100% capacity healthcare system is that they still have to *try* and take care of the ill, even if it means everyone's quality of care goes down a little.01:52
TuvixWe've had some reports now and then where someone died from what should have been a preventable non-COVID condition simply becuase they couldn't get the care or treatment they needed in time.01:53
TuvixIt's not super-common, but that's certainly a contributing factor to some increase in adverse outcomes.01:53
BrainstormNew from r/Coronavirus: Coronavirus: New covid variant IHU found to have 46 mutations → https://old.reddit.com/r/Coronavirus/comments/rx1muo/new_covid_variant_ihu_found_to_have_46_mutations/01:58
TimvdeAlready a new one? Oh, come on.01:59
anarchatnot sure that's a reputable source01:59
anarchathttps://www.nydailynews.com/coronavirus/ny-covid-new-variant-46-mutations-france-cameroon-20220105-gasci4tizzfltftc3yg4s7kyre-story.html02:00
anarchatmaybe02:00
anarchatalso, reddit says "if that's the french one, it's not a problem"02:00
anarchatbut i'd bet my shorts that we're going to have a new variant of concern soon enough, with such explosion02:00
TimvdeWoops, it's past 2 AM02:06
TimvdeGood night :p02:06
TuvixLater!02:07
BrainstormNew from r/Coronavirus: Coronavirus: Mayo Clinic fires 700 employees for failing to comply with COVID-19 vaccine mandate → https://old.reddit.com/r/Coronavirus/comments/rx1rym/mayo_clinic_fires_700_employees_for_failing_to/02:08
sdfgsdfghttps://www.reddit.com/r/COVID19/comments/rwt3qu/multiorgan_assessment_in_mainly_nonhospitalized/02:08
sdfgsdfg.title02:08
Brainstormsdfgsdfg: From www.reddit.com: Multi-organ assessment in mainly nonhospitalized individuals after SARS-CoV-2 infection. The Hamburg City Health Study COVID programme : COVID1902:08
sdfgsdfgshit... this is what I was looking for02:08
TuvixOh man, that's a major helathcare system around this area that Brainstorm just mentioned. You'd think healthcare workers would know better than that…02:09
sdfgsdfgfrom 7 hours ago, this must be a new study02:09
Tuvix"The clinic said that the majority of medical or religious exemption requests made by employees in response to the mandate were granted."02:09
BrainstormUpdates for India: +87222 cases (now 35.1 million), +60 deaths (now 482611) since 5 hours ago — France: +443508 cases (now 11.0 million), +587 deaths (now 125787) since 5 hours ago — Netherlands: +46456 cases (now 3.3 million), +58 deaths (now 21497) since 5 hours ago — Australia: +43333 cases (now 634125), +12 deaths (now 2295) since 5 hours ago02:11
sdfgsdfgexemptions are crazy but take a look at this:02:15
sdfgsdfg"How does a mild to moderate course of SARS-CoV-2 infection in mainly non-hospitalized individuals impact intermediate-term organ-specific functions in comparison to the general population? The key findings are (i) a mild to moderate course of SARS-CoV-2 infection is associated with subsequent signs of subclinical multi-organ affection; (ii) associations mainly affect the pulmonary, cardiac, coagulation, and renal system; and (iii) no systematic02:15
sdfgsdfg associations with structural brain damage, neurocognition, or quality of life were observed. The take-home message is systematic screening of multi-organ function even after mild to moderate SARS-CoV-2 infection is recommended to identify individuals at risk and initiate appropriate preventive therapies"02:15
Tuvixsdfgsdfg: And there are a half-dozen studies showing substantial issues. Did you notice the exclusions of youth in this study? Or the time-range that means Delta & Omicron (obviously the later since it's not been out long enough yet) weren't included?02:16
sdfgsdfgwe would find out about delta and omicron's multi-organ damage only at the end of 2022 and after half a year to have a survey like this though...02:17
TuvixThere's a growing amount of scientific evidence, not to mention pandemic-long anectital reports, of a certain incidence of significant impairment weeks or months after infection. This seems not to be the norm as far as the data shows, but "no [such effects are observed]" may be tru for _that_ study, but it's certainly not true for patients with actual clinically documented conditions.02:17
sdfgsdfgor mid 2022 or something02:17
sdfgsdfgright, that's also weird that healthy younglings aren't included02:18
Tuvixhttps://www.medrxiv.org/content/10.1101/2021.06.11.21258690v302:21
Tuvix"The 401 SARS-CoV-2 infected participants also showed larger cognitive decline between the two timepoints in the Trail Making Test compared with the controls [..] Unlike in post hoc cross-sectional studies, the availability of pre- infection imaging data mitigates to some extent the issue of pre-existing risk factors or clinical conditions being misinterpreted as disease effects."02:22
TuvixI don't really get your point here. You seem to be trying to throw doubt on what's becoming increasingly apparent that at least a portion of patients have lasting impacts from this, by pointing to a study that finds "no" such evidence of this.02:24
TuvixFurther note that the paper you linked is almost entierly non-hospitalized patients; meanwhile the recent Nature article points out that another study found 80% incidence rate in the hospitalized population.02:26
TuvixReferences: https://www.nature.com/articles/d41586-021-01693-6  w/ citations: https://pubmed.ncbi.nlm.nih.gov/33974053 & https://www.medrxiv.org/content/10.1101/2021.06.11.21258690v302:26
sdfgsdfgwhat are you tripping on about again, I just shared a survey from 7 hours ago02:27
sdfgsdfgI started reading it after I posted02:27
sdfgsdfgenjoy reading it please02:27
sdfgsdfgevery survey is precious, I'm not opinionated - the assumption is dangerous02:27
TuvixYes, I read the full abstract and provided at least 4 other things you can read that show the exact opposite of what you quoted and the abstract concluded.02:28
Raf[m]That's a nice preprint02:29
Raf[m]Good they have pre and post imaging02:29
TuvixYea, it's hugely siginificant that the pre-imagine was pre-COVID.02:29
Tuvixpre-imaging*02:30
Tuvixsdfgsdfg: You never answered me. What's the conclusion you're drawing from the study you linked that seems not to match the emerging reserach in this area over the past month or two? And maybe explain why a study you linked that excluded the under-40's would have any relevance to "healthy younglings"? (in US anyway, we're seeing record high numbers of youth in critical conditions)02:35
sdfgsdfgI'm writing02:35
sdfgsdfghold on02:35
sdfgsdfgdo you think this paper contradicts the findings of long term damage on all organs ? No, it confirms them02:37
sdfgsdfgespecially with very mild cases02:37
sdfgsdfgand I think that's the point here02:37
sdfgsdfgyou might think you're safe without severe symptoms, or ending up in hospital02:37
sdfgsdfgand that was the consensus earlier02:38
sdfgsdfgI honestly wasn't interested in age group differences, this is more interesting to me02:39
TuvixIt seems to miss the point about long-covid with documented mental/neurological cases non-hospitalized people too, though I wonder if the study was either not big enough or had too many limitations to see that.02:40
sdfgsdfgthat's completely right, and they missed it probably because the work was mainly on very mild cases02:40
sdfgsdfgwhich is why they mention further research would be needed etc02:40
sdfgsdfgI'm skeptical on that as well02:40
sdfgsdfgneurological consequences are obviously there - especially with so many long covid patients02:41
TuvixWell, monitoring is what they say, and that's actually a reasonable conclusion, but the fact that they saw _no_ long-term effects with significant impairment doesn't match the the over-45 year olds in the UK Biobank study. I'm digging into the details on that preprint to see if there's an obvious enough change in methods used (besides the obvious pre-covid brain scan) that might indicate why.02:43
TuvixSo, upfront what jumps out at me is no notable difference in the Biobank study between hospitalized (n=15) and non-hospitalized (n=386) COVID-positive cases.02:45
TuvixGranted n=15 is a far smaller sample size, but you'd expect if severity was an notable factor, that there'd be at least _some_ difference in those groups when compared to the control.02:46
BrainstormNew from Reddit (test): nCoV: Record Number of COVID-19 Infections Reported in Australia → https://old.reddit.com/r/nCoV/comments/rx1zeg/record_number_of_covid19_infections_reported_in/02:46
TuvixThe other notable thing from the introduction & abstract is that the scans noted very localized abnormalities with in particular the olfactory system; given that's one of the viruses main entry points, this is also an interesting finding if it's part of the reason why some people experience these long-term brain-based impacts later.02:48
TuvixI still don't get what the Hamburg study means by "Subjects who apparently recovered from mild to moderate [COVID]" -- are they excluding people who didn't "apparently recover" from the conclusion that there was "[no sign of] neurocognitive, or quality-of-life impairment" ?02:51
TuvixBecause that's exactly the opposite conclusion from the brain-scans in Biobank conclude: "In both [specific and general imaging tests] we identified significant effects associated with SARS-CoV-2 infection primarily relating to greater atrophy and increased tissue damage in [brain areas connected to the olfactory center …]"02:56
BrainstormNew from r/Coronavirus: Coronavirus: S. Korea: Daily virus cases over 4,000 for 2nd day amid omicron woes → https://old.reddit.com/r/Coronavirus/comments/rx2kdy/s_korea_daily_virus_cases_over_4000_for_2nd_day/02:56
Tuvixsdfgsdfg: I think the core of the issue is the testing methods; Biobank had more detailed imaging and thousands of "IDP" points of analysis (basically a metric to compare the before/after images.) Hamburg by comparison had a rather limited set of organ-specific function evaluation.02:59
sdfgsdfgthis is the biobank research you're referring to right ? https://www.biorxiv.org/content/10.1101/2021.01.17.427024v1   in this one I think they found that it affects different brain cells03:00
sdfgsdfg"In the five whose brain cells showed evidence of SARS-CoV-2 infection, 66% of the affected cells were astrocytes. Infected astrocytes could explain some of the neurological symptoms associated with COVID-19, especially fatigue, depression and ‘brain fog’, which includes confusion and forgetfulness, argues Kriegstein"03:00
TuvixNo, the one I linked earlier: https://www.medrxiv.org/content/10.1101/2021.06.11.21258690v303:01
Tuvixie: the one with 'Biobank' in the title, ergo my reference to it as such.03:01
sdfgsdfgthumbs up, I must have missed this one, looks like a niice study and a great afternoon read - I'll make tea and get into it soon :)03:02
BrainstormNew from r/Coronavirus: Coronavirus: Victorian COVID-19 restrictions tighten with density limits and mandatory rapid test reporting → https://old.reddit.com/r/Coronavirus/comments/rx2lrt/victorian_covid19_restrictions_tighten_with/03:05
BrainstormUpdates for Guatemala: +1919 cases (now 631730), +3 deaths (now 16114), +9676 tests (now 3.3 million, 0.0% positive) since 5 hours ago — Albania: +1236 cases (now 213257), +4 deaths (now 3228) since 5 hours ago — Egypt: +803 cases (now 389454), +27 deaths (now 21863) since 5 hours ago [... want %more?]03:07
Tuvixp31 of the Biobank also notes, "significantly great cognitive decline [even in the non-hospitalised patients] was seen in the SARS-CoV-2 positive group […] associated with greater atrophy […]"03:21
Tuvixgreater*03:22
TuvixIntresting discussion on the following page (p32) though, where they hint that the volume of the thalamus might be a predictor of likelyhood of infection. <- de-facto , rather intresting conclusion from the UK Biobank brain imaging preprint03:24
TuvixAnd reading a bit further, yet another indication of the importance of vaccination and mitigation, p36: "… marked atrophy of fronto-parietal and temporal [brain] regions can also be seen when contrasting hospitalised and non-hospitalised cases, suggesting increased damage in the more moderate and severe cases […]"04:07
BrainstormUpdates for Mexico: +20626 cases (now 4.0 million), +94 deaths (now 299805), +49378 tests (now 12.5 million, 41.8% positive) since 6 hours ago — Thailand: +5775 cases (now 2.2 million), +11 deaths (now 21780) since 6 hours ago — South Korea: +4123 cases (now 653792), +49 deaths (now 5887) since 6 hours ago [... want %more?]04:08
BrainstormNew from r/Coronavirus: Coronavirus: Classes again canceled for Chicago Public Schools on Thursday → https://old.reddit.com/r/Coronavirus/comments/rx3t3v/classes_again_canceled_for_chicago_public_schools/04:29
BrainstormNew from r/Coronavirus: Coronavirus: A record-high number of kids are getting hospitalized with Covid-19 as overall Covid-19 hospitalizations soar past the Delta peak → https://old.reddit.com/r/Coronavirus/comments/rx43nl/a_recordhigh_number_of_kids_are_getting/04:39
sweetsymphTuvix: that brain damage some people get is worrying to me. Even people who didn't get covid severely but get long covid are sometimes having problems I heard.04:44
sweetsymphThat is why when people say omicron is "mild" as it isn't killing as many people is a worry to me. Mild brain damage?04:45
BrainstormNew from r/Coronavirus: Coronavirus: Can weight loss help protect against Covid-19? → https://old.reddit.com/r/Coronavirus/comments/rx442l/can_weight_loss_help_protect_against_covid19/04:48
LjLsweetsymph, we don't know whether omicron causes the same long-term "issues" as delta, we just don't at this point04:57
LjLnot downplaying it... but it may, or it may not04:57
critra virus with twice the infection rate and half the death rate will have about the same overall outcome in any given population.04:57
BrainstormNew from r/Coronavirus: Coronavirus: Cedar allergies soar in Central Texas causing COVID confusion → https://old.reddit.com/r/Coronavirus/comments/rx4gf3/cedar_allergies_soar_in_central_texas_causing/04:58
LjLactually no04:58
LjLif it has *twice the infection rate*, it will cause many, many more deaths04:58
LjLbut that says nothing about brain damage and such anyway04:58
critrif you have 100 people exposed to a virus with a 50% infection rate and a 10% death rate among the infected, you will get about 5 deaths. if the virus has a 100% infection rate and a 5% death rate among the infected, you get about 5 deaths.05:01
LjLinfection growth is exponential. death isn't.05:01
LjLso yes, what you said works, *for the first iteration only*05:01
LjLif a virus is twice as infectious as another, it will growth exponentially faster, not just "twice as fast"05:02
critrgood point.05:02
BrainstormNew from NPR: California extends its indoor mask mandate until February as omicron surge continues: So far, nearly 80% of California residents have been vaccinated with at least one dose of the COVID vaccine. The extended statewide mask mandate is set to expire on [... want %more?] → https://www.npr.org/sections/coronavirus-live-updates/2022/01/05/1070811627/california-indoor-mask-mandate05:07
BrainstormUpdates for Zimbabwe: +1379 cases (now 219057), +14 deaths (now 5092), +6885 tests (now 1.9 million, 20.0% positive) since 8 hours ago — Suriname: +916 cases (now 55376), +1 deaths (now 1193), +1981 tests (now 176922, 46.2% positive) since 8 hours ago — Grenada: +314 cases (now 7101), +1534 tests (now 99585, 20.5% positive) since 8 hours ago [... want %more?]05:11
LjLBrainstorm seems to be making up for all the updates it didn't send in the past few days05:19
zadR10 each person infects 10 ?05:26
LjLthat's the idea05:26
LjLit's not called R10 though, it's called R0=10 :P05:26
zadevery friggin graph is straight up for gods sake05:26
LjLor R<something>=10 depending on what exactly you're measuring05:27
gry"infection growth is exponential. death isn't."05:27
grywhy death isnt05:27
LjLbecause death doesn't infect :P05:27
gryall other factors being equal, death from the virus is proportion of infection growth, no?05:27
LjLyes05:27
gryok05:27
grysydney badle screwed it up i think05:28
grybadly05:28
zaddeath is a trailing indicator, by the time you see that, it's over05:28
zadyou could have done something, now it's another SS  , humans ..05:28
LjLgry, what i meant is that deaths are going to be many more than "the same", if you have a virus that infects double but kills half05:28
LjLbecause the half just remains half, but the double keeps doubling05:28
LjLthe half is eventually also exponential, yes, because it's following the double05:29
LjLbut there is no exponential factor bringing deaths *down* so that they become even with the other virus05:29
Telvanazad: What's scary about a graph going straight up? The fact that said graph drops just as fast ... which is scary considering the ramifications of *why* it came down that fast.05:37
zaduhm, think thats a dumb question05:39
TelvanaDid you read the rest of my statement? Apparently not05:39
LjLTelvana, why does it come down just as fast?05:41
LjLi've been asking myself that question for a long time05:42
TelvanaWell, hopefully not for the same reason Delta dropped off, which was a lot of death, a lot of injured, and a lot of messed up hospitals05:42
TelvanaDelta was also swallowed by Omicron, so there is that as well05:43
TelvanaBut that's not why it dropped off, of course05:43
TelvanaI am curious to see if Omicron w/ it's R0 of 10 is powerful enough to blow through the population and burn itself out (good chance that's not going to happen, but it is a curiosity, and I think that's what happened in South Africa)05:45
BrainstormNew from COVID on Twitter: Tulio de Oliveira (@Tuliodna): Cuba’s vaccine success story sails past mark set by rich world’s Covid efforts  theguardian.com/world/2022/jan… → https://twitter.com/Tuliodna/status/147894752717725286405:55
LjL<Brainstorm> New from EuroNews: Brussels must be involved in Ukraine talks, says EU foreign minister: US and Russian officials are due to hold security talks in Geneva on Monday amid mounting tensions over Ukraine. #BrusselsBureau → https://www.euronews.com/2022/01/05/brussels-must-be-involved-in-ukraine-talks-says-eu-foreign-minister05:55
LjLerr, i'm sorry, that was the wrong paste -.-05:56
LjL<Brainstorm> New from EuroNews: Brussels mulls joint EU purchase of new antiviral COVID pills: The European Commission is in talks with pharmaceutical companies to buy the antiviral pills, which can be taken orally at home. #BrusselsBureau → https://www.euronews.com/2022/01/05/brussels-mulls-joint-eu-purchase-of-new-antiviral-covid-pills05:56
LjLis what i meant05:56
LjLit's about both Paxlovid and (sigh) Molnupiravir05:56
BrainstormUpdates for Belgium: +27796 cases (now 2.2 million), +22 deaths (now 28429), +102031 tests (now 27.6 million, 27.2% positive) since 8 hours ago — Germany: +77239 cases (now 7.4 million) since 8 hours ago — Japan: +2955 cases (now 1.7 million), +3 deaths (now 18398), +88375 tests (now 29.6 million, 2.1% positive) since 8 hours ago [... want %more?]06:01
Tuvixsweetsymph: Side effects, including long-term ones, are worth keeping an eye on, but even that preprint I was quoting from with the imaging studies still reveals what I think most of us have known for some time; being vaccinated and taking percautions to prevent or even just reduce our exposure potency all incrementally improve our odds of avoiding or reducing infection impacts.06:02
BrainstormNew from r/Coronavirus: Coronavirus: CDC signs off on Pfizer Covid vaccine boosters for adolescents → https://old.reddit.com/r/Coronavirus/comments/rx5x6e/cdc_signs_off_on_pfizer_covid_vaccine_boosters/06:05
sweetsymphThat is a relief. Pretty thankful to have had three shots, they should help a bit. I keep thinking about the people I know who didn't get any vaccine though and their risk factors. Some are obese. One has type 1 diabetes. I hope they will be ok. I tried to convince some to get the vaccine but if they are set in their opinion, it is a hard one. A bit sad if they get it severely when they could have been protected.06:07
TuvixIt's tough, for sure. It's affected some of the groups and cost me one social venue I used to go to regurlarly who refuses to take even basic measures like testing known close contacts of tested-positive cases.06:08
TuvixInformation can help some of them who are simply misinformed and bought into the false messaging, but the people who refuse to believe on idological grounds are often a lost cause.06:09
TuvixFor the former, graphs like I put together on CDC data (only through October, since newer data isn't yet easily available yet) can help: https://imgur.com/a/Lm9sdzR06:09
TuvixThat shows a clear indication that, regardless of age group, you are _better_ off against COVID being vaccinated than not, and during the delta peak your protection from death was up to and even over 40x for certain age-groups. But this won't help people who reject all science, or just find another conspiracy theory to use instead.06:11
critrevolution in progress.06:16
TuvixAs to your vaccination, yes, it helps, but also think of it in the context of risk mitigation; avoiding unnecessary social gatherings, especially in risky settings (bars/dining, larger groups, groups from many households, etc) and wearing a quality mask properly where social proximity is require all help reduce that risk more.06:18
TelvanaMolnupiravir seems a bit too risky06:19
TuvixI'm not entierly sure on the risks since I only have a broad understanding of the molecular properties iat play with that treatment, but the mutagenic operation and possible unintended mutations seem a lot less desirable than paxlovid by comparison. The rub with Pfizer's antiviral is that it'll be severely supply-limited for 6 to 12 months.06:23
BrainstormNew from r/WorldNews: worldnews: Pandemic may affect infants brain development; coronavirus can trigger kidney scarring → https://old.reddit.com/r/worldnews/comments/rx6dqu/pandemic_may_affect_infants_brain_development/06:33
critrcovid-19 is so much worse than i originally thought -- that there would be an enormous number of deaths of the old and sick, and then it would be essentially over.06:41
BrainstormNew from r/Coronavirus: Coronavirus: Should I Just Get Omicron Over With? "If you’re vaccinated, an infection might not make you super sick, but don’t count on it making you super immune, either." → https://old.reddit.com/r/Coronavirus/comments/rx6jhk/should_i_just_get_omicron_over_with_if_youre/06:43
critra lot of people (like me) were thinking that in 2020. "ah, just get covid-19 and recover and then it's all good again." what a lot of fools we were.06:46
DreddTuvix: the question really is whether the mutation rate with the drug leads to increased beneficial mutations or not. It really should be looked into imo06:47
BrainstormUpdates for England, United Kingdom: +149350 cases (now 11.7 million), +316 deaths (now 129815) since 9 hours ago — New York, United States: +76000 cases (now 3.8 million) since 9 hours ago — California, United States: +59691 cases (now 5.8 million) since 9 hours ago — Lombardy, Italy: +51587 cases (now 1.4 million), +47 deaths (now 35240) since 9 hours ago07:04
BrainstormNew from r/WorldNews: worldnews: Covid-19: India records first death linked to Omicron variant → https://old.reddit.com/r/worldnews/comments/rx72m3/covid19_india_records_first_death_linked_to/07:11
BrainstormNew from r/Coronavirus: Coronavirus: Emerging Data Raise Questions About Antigen Tests and Nasal Swabs → https://old.reddit.com/r/Coronavirus/comments/rx76hs/emerging_data_raise_questions_about_antigen_tests/07:20
TuvixDredd: No mutations are beneficial. Omicron would be a "beneficial" mutation if it really is less severe. But it's really shitty instead since it'll probably end up doing more harm at least in the short term to hospitals (at least around where I am) than even Delta did. Most reputatible immunological scientists I've heard on the matter would disagree that the "goal" is to spur mutations on purpose.07:31
TuvixThe drug effectivly works by causing enough mutations so the virus can't replicate in the body and the immune system can see and attack the infection instaed of letting it evade the immune system. But mutations that are better at evading immunity from the T- & B-cells is a possibility too, and a far less optimistic one.07:32
bluescluesthere is a new variant out there now07:33
bluescluesIHS07:33
TuvixThere are many, but most don't rise to a Varient of Concern, just 5 big ones plus the original.07:33
DefiantNIs there a study on the chances of severe covid or death after two shots of pfzier vs 3 in healthy adults?07:38
BrainstormNew from r/Coronavirus: Coronavirus: Fourth COVID-19 vaccine dose boosts antibodies five-fold in Israeli study, PM says → https://old.reddit.com/r/Coronavirus/comments/rx7ksb/fourth_covid19_vaccine_dose_boosts_antibodies/07:39
TuvixDefiantN: It is so close to zero that the risk, while not actually zero, is so much lower than a healthy adult having complications that lead to death from COVID that you want to get vaccinated anyway. There is for example https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8052499/ , but not that death _after_ vaccination does *not* neceesarily imply a causality relationship.07:44
TuvixDefiantN: The reason question you should be asking is "are more people dying than would be expected to die in that timeperiod anyway" -- in which case the answer is as close to "no" as you can get. You might also die crossing the road tomorrow, but so long as you look both ways before you do my guess is you'll do pretty well.07:45
TuvixDefiantN: As a specific example, Case 2 in that linked study was almost certainly a fatality from a SARS-CoV-2 infection that just happened to occur near the time vaccination was given. Ironically, being vaccinated and protected sooner might have improved that indivdiauls odds, but it's a bit late by then.07:47
BrainstormNew from MedicineNet: (news): Immune System T-Cells Can Fight Off Omicron → http://www.medicinenet.com/script/main/art.asp07:49
DefiantNYea, I don't really want the booster. But I suspect my work will mandate it soon07:52
DefiantNAt least not after barely 6 months07:52
TuvixMany vaccinations are given in a 1st dose, 2nd dose in about a month, and a 3rd dose at 6 months after. The real issue is the impact on outcomes in those who have been boosted, which are significantly better.07:53
TuvixThis time series is not at all unique to this virus. Other ailments you need periodic boosters for as well, such as tetanus.07:54
TuvixSome years back I stepped on a very dirty, slightly rusty nail moving some pallets, and it went fairly deep into my toe. I wasn't seriously injured, but went to a clinic anyway since I didn't recall when my last booster was (not a great sign..)07:55
DefiantNI was asking about the benefit. Is there a measurable benefit of having 2 shots of pfzier or 3 in healthy adults07:55
TuvixTurns out I was "technically" within the typical 10-year booster window, but given my recent exposure the clinic informed me I'd be safter with an additional boosterd ose.07:55
TuvixYes, there's a significant improvement in protection, especially with Omicron.07:56
TuvixOmicron has somewhat weaker protection with the existing vaccines, but that loss in protection is largely made up for with the booster dose. In terms of what happens in your body, your cells (T- & B-cells) have been "primed" with the first 2 doses, but aren't as well trained to fight some of the varients, like delta and especially Omicron.07:57
TuvixWhat a booster dose dose is recall the memory from your initial dossing, and the next-generation of cells are more potent and better at creating antibodies to fight infection. Over 1 to 3 weeks these "better fighters" result in cell memory in your B-cells which live in your lymph nodes.07:58
TuvixDefiantN: I'm not sure where you're located, but if you wanted a more technical paper on the subject, this one is largely a summary of the data reviewed and the reasoning behind it: https://www.cdc.gov/vaccines/acip/recs/grade/covid-19-booster-doses.html08:00
BrainstormUpdates for Czechia: +7422 cases (now 2.5 million), +52 deaths (now 36449) since 10 hours ago — Panama: +4372 cases (now 507779), +21991 tests (now 4.6 million, 19.9% positive) since 10 hours ago — Uzbekistan: +146 cases (now 199507) since 10 hours ago — Cambodia: +18 cases (now 120553) since 10 hours ago08:00
DefiantNThanks08:02
Dredd<Tuvix> "Peter: No mutations are benefici..." <- Ah, I meant for the virus 😂08:10
TuvixOh, right. Yea, the risk is that something that is actually better at infecting or causing symptoms (ergo bad for humans) results _and_ can replicate well enough to spread further.08:11
Tuvixreally paxlovid is the better antiviral, but there's just no way that alone is going to be enough for the global demand for treatments.08:12
TuvixThe real shame is that some of those who are going to be relying on these would have had vastly improved odds to begin with if they'd gotten vaccinated and we wouldn't need to consider the implications of more mutagenic alternatives in as many cases, but I'll leave it up to the doctors and immunological experts on what the emerging data reveals.08:13
TuvixIt could well be that the dangers of that are quite low, and as always it's a risk mitigation; sometimes you're stuck choosing the least-awful option when you don't have good ones.08:14
Dredd<Tuvix> "Oh, right. Yea, the risk is that..." <- Yeah, it might lead to more beneficial mutations but also the balance might come down of the side of tweaking up the evolution dial being less optimal for its evolution08:17
DreddI guess the only way to tell is to study it08:17
DreddThe other paxlovid issue is the drug interactions too08:18
TuvixThe only way that's good is in the case of zero spread. The idea of trying to introduce a new varient to displace Omicron or whatever is just such a mess that it's really no more useful than the "just infect everyone at once and ignore the lack of hospital support we'll have for the critically ill" appraoch.08:18
TuvixRight, the drug interaction is a problem with paxlovid, since the list of problematic medication is significant.08:19
DreddIn terms of treatment to use, maybe molupnivir could be useful as an addition to paxlovid to further increase effectiveness?08:20
TuvixI think that's been more commonly used with some of the antibody treatments, and some of those are already a mix of several combined.08:21
TuvixOf course, 2 of the more successful mAb treatments are now basically off the table with Omicron…08:21
DreddTuvix: Wrt mutations, I mean if the mutation rate is too high but not enough to lead to nonviable mutants it could still make it difficult to accumulate fitness improving mutations without significant reducing ones so it's a wash08:22
DreddI'd definitely like to see the effect on COVID evolution / new variant fitness looked into further08:23
TuvixRight, and that's the big question. I just don't know enough about the field to have a good understanding on that, but I wonder how well that question actually *has* been evaluated for this application.08:23
DreddThe closest we can get to a cocktail of things attacking several different mechanisms that are that's hard for covid too escape all at once, the better for getting the lid on covid ala HIV08:24
TuvixIt's an interesting idea, but here again, supply is the real problem. If we need alternatives in part because of lack of production, we can't exactly give 2 when there may not be enough for patients who would otherwise be eligible even 1.08:26
Tuvix+for08:26
TuvixIf my handsoap had an even small chance, instead of washing away the dirt, to create a dirt-fountain that would flood dirt all over the rest of me, I'd probably switch soap brands :P08:29
TuvixBut, if that was the _only_ soap I had, and I knew I had other nasty stuff on me, sure, maybe I'd take my odds…08:29
BrainstormNew from r/Coronavirus: Coronavirus: Australia suffers record COVID-19 cases, straining businesses and supply chains → https://old.reddit.com/r/Coronavirus/comments/rx8izs/australia_suffers_record_covid19_cases_straining/08:36
BrainstormNew from Reddit (test): CoronaVirus_ITALIA: CRISANTI: “OBBLIGO VACCINALE È FOLLIA SANITARIA OLTRE CHE INCOSTITUZIONALE...NON SI PUO' IMPORRE SENZA UNA REVISIONE DEL "CONSENSO INFORMATO". PREVISTA PIOGGIA DI RICORSI. → https://old.reddit.com/r/CoronaVirus_ITALIA/comments/rx8py5/crisanti_obbligo_vaccinale_è_follia_sanitaria/08:46
BrainstormNew from r/Coronavirus: Coronavirus: Singapore to give out free N-95 grade masks to all residents → https://old.reddit.com/r/Coronavirus/comments/rx8rok/singapore_to_give_out_free_n95_grade_masks_to_all/08:55
BrainstormNew from Politico: French MPs approve new COVID vaccine pass: Lawmakers vote as France hits record number of coronavirus cases. → https://www.politico.eu/article/french-parliament-approves-covid-vaccine-pass/09:14
BrainstormNew from r/Coronavirus: Coronavirus: U.S. bases in Japan requested to impose curfews amid COVID spread → https://old.reddit.com/r/Coronavirus/comments/rx9cp2/us_bases_in_japan_requested_to_impose_curfews/09:33
BrainstormNew from r/Coronavirus: Coronavirus: Pfizer expects updated COVID-19 vaccine data for kids under 5 by April → https://old.reddit.com/r/Coronavirus/comments/rx9lly/pfizer_expects_updated_covid19_vaccine_data_for/09:52
BrainstormUpdates for Maharashtra, India: +26538 cases (now 6.8 million), +8 deaths (now 141581) since 12 hours ago — West Bengal, India: +14022 cases (now 1.7 million), +17 deaths (now 19827) since 12 hours ago — Delhi, India: +10665 cases (now 1.5 million), +8 deaths (now 25121) since 12 hours ago [... want %more?]09:59
BrainstormNew from r/Coronavirus: Coronavirus: India’s coronavirus cases rise as omicron spreads — and as election season heats up → https://old.reddit.com/r/Coronavirus/comments/rx9teh/indias_coronavirus_cases_rise_as_omicron_spreads/10:11
BrainstormNew from r/Coronavirus: Coronavirus: Spain now has the highest Covid infection rate in Europe → https://old.reddit.com/r/Coronavirus/comments/rxa2jl/spain_now_has_the_highest_covid_infection_rate_in/10:20
BrainstormNew from r/Coronavirus: Coronavirus: Omicron: suspected Covid-19 patient believed to be among 100 guests at birthday party that included Hong Kong officials, civil servants → https://old.reddit.com/r/Coronavirus/comments/rxa4r1/omicron_suspected_covid19_patient_believed_to_be/10:30
BrainstormNew from r/WorldNews: worldnews: Novak Djokovic Is Refused Entry Into Australia Over Vaccine Exemption → https://old.reddit.com/r/worldnews/comments/rxae23/novak_djokovic_is_refused_entry_into_australia/10:39
Dreddhttps://youtu.be/cLoMGb5CaXE10:48
BrainstormNew from StatNews: First Opinion: Opinion: Containing Covid-19 requires rapid tests that are highly sensitive to infections. Why is the FDA asking for something different? → https://www.statnews.com/2022/01/06/make-home-covid-19-tests-highly-sensitive-to-infection/10:48
DreddThis made me chuckle and think of some of the more fringe views around covid 😂10:48
aradeshaustralia deporting djokovic10:49
sdfgsdfgI thought we let him stay for a while ?10:53
sdfgsdfguntil Monday ! So there will be a hearing... Apparently he needs to be told to **** off twice ... lol10:55
BrainstormUpdates for Philippines: +17172 cases (now 2.9 million), +81 deaths (now 51743) since 13 hours ago — Israel: +19392 cases (now 1.4 million) since 13 hours ago — Ukraine: +13232 cases (now 3.9 million), +643 deaths (now 103201) since 13 hours ago — Indonesia: +533 cases (now 4.3 million), +7 deaths (now 144116), +274727 tests (now 64.7 million, 0.2% positive) since 13 hours ago11:02
BrainstormNew from r/Coronavirus: Coronavirus: Australia suffers record COVID cases, straining businesses and supply chains → https://old.reddit.com/r/Coronavirus/comments/rxapw7/australia_suffers_record_covid_cases_straining/11:08
sdfgsdfgI'm surprised he appealed, now he's going to be locked up in a detention-like covid quarantine hotel for 3 days until his private grand finale in a courtroom with our minister of home affairs. This is even better than a tennis tournament if you ask me11:16
sdfgsdfgI wouldn't have watched the tennis, but this is better than the american presidential elections11:16
sdfgsdfgwell, almost*11:17
BrainstormNew from r/Coronavirus: Coronavirus: Two 6-year-old children die of COVID-19 at Soroka Hospital (Israel, both unvaccinated) → https://old.reddit.com/r/Coronavirus/comments/rxazhc/two_6yearold_children_die_of_covid19_at_soroka/11:17
aradeshi'd be surprised if he hasn't got an official exemption though11:36
aradeshlike11:36
aradeshi don't believe he hasn't got a serbian doctor who will produce the documentation he needs, whether true or not11:36
BrainstormNew from EMA: What's new: Orphan: Orphan designation: Human plasminogen, Treatment of plasminogen deficiency, 28/07/2015, Positive → https://www.ema.europa.eu/en/medicines/human/orphan-designations/eu-3-15-151111:36
aradeshwe all know there is an entire industry of dodgy doctors in sport11:37
aradeshso he might even win an appeal11:37
sdfgsdfgI think he has some natural immunity cert maybe ?11:39
sdfgsdfgand it's not recognized here. I remember complaining about it here before... hahaha11:39
BrainstormNew from BMJ: Vaccine equity . . . and other stories: Vaccine equityAs long as wealthy nations buy most of the available vaccine stock and leave low and middle income countries at the back of the queue, new variants of SARS-CoV-2 will continue to arise.... → http://www.bmj.com/content/376/bmj.n3155.short11:46
BrainstormNew from EMA: Human medicine assessment reports: (news): Human medicines European public assessment report (EPAR): Comirnaty, Tozinameran,COVID-19 mRNA Vaccine (nucleoside modified), COVID-19 virus infection, Date of authorisation: 21/12/2020, Revision: 18, Status: Authorised → https://www.ema.europa.eu/en/medicines/human/EPAR/comirnaty11:56
BrainstormUpdates for Poland: +16577 cases (now 4.2 million), +645 deaths (now 99311), +105419 tests (now 27.7 million, 15.7% positive) since 15 hours ago — Russia: +15316 cases (now 10.6 million), +802 deaths (now 313817), +400000 tests (now 242.3 million, 3.8% positive) since 15 hours ago [... want %more?]12:11
BrainstormNew from r/Coronavirus: Coronavirus: At least 24 NHS trusts declare critical incidents due to Covid pressures → https://old.reddit.com/r/Coronavirus/comments/rxby0k/at_least_24_nhs_trusts_declare_critical_incidents/12:15
aradeshsdfgsdfg: i see12:39
BrainstormNew from r/Coronavirus: Coronavirus: Indonesia survey finds 85 per cent of population have Covid-19 antibodies → https://old.reddit.com/r/Coronavirus/comments/rxciyl/indonesia_survey_finds_85_per_cent_of_population/12:53
BrainstormUpdates for Finland: +5979 cases (now 295601), +8 deaths (now 1632), +22825 tests (now 8.8 million, 26.2% positive) since 15 hours ago — UAE: +2687 cases (now 777584), +405418 tests (now 113.9 million, 0.7% positive) since 15 hours ago — Saudi Arabia: +2153 cases (now 568650), +1 deaths (now 8888) since 15 hours ago [... want %more?]13:01
BrainstormNew from r/Coronavirus: Coronavirus: Walmart halves paid leave for COVID-positive workers → https://old.reddit.com/r/Coronavirus/comments/rxckuw/walmart_halves_paid_leave_for_covidpositive/13:03
BrainstormNew from BBC Health: Covid: Evidence on face masks in schools 'inconclusive': Government admits uncertainty over whether face coverings will truly cut Covid spread. → https://www.bbc.co.uk/news/health-5989593413:13
BrainstormNew from r/Coronavirus: Coronavirus: More than 100 test positive on an Italy-India flight - BBC News → https://old.reddit.com/r/Coronavirus/comments/rxd6vj/more_than_100_test_positive_on_an_italyindia/13:32
BrainstormNew from Reddit (test): nCoV: Global COVID Cases For 07JAN22 → https://old.reddit.com/r/nCoV/comments/rxd8zs/global_covid_cases_for_07jan22/13:41
BrainstormNew from r/WorldNews: worldnews: Italy makes vaccines mandatory for over-50s → https://old.reddit.com/r/worldnews/comments/rxdgfg/italy_makes_vaccines_mandatory_for_over50s/13:51
BrainstormNew from r/Coronavirus: Coronavirus: 84-year-old Bihar man gets 11 Covid vaccine shots, caught while going for 12th → https://old.reddit.com/r/Coronavirus/comments/rxdoic/84yearold_bihar_man_gets_11_covid_vaccine_shots/14:01
BrainstormUpdates for Romania: +6018 cases (now 1.8 million), +44 deaths (now 58940), +62842 tests (now 17.3 million, 9.6% positive) since 16 hours ago — Zambia: +4096 cases (now 274087), +10 deaths (now 3782), +14221 tests (now 3.0 million, 28.8% positive) since 16 hours ago — Iceland: +1338 cases (now 35239), +8954 tests (now 1.4 million, 14.9% positive) since 16 hours ago [... want %more?]14:03
oerheksDo we hit 300m today ? https://www.worldometers.info/coronavirus/#countries14:37
BrainstormNew from r/Coronavirus: Coronavirus: UK: Evidence on face masks in schools 'inconclusive', according to Government study → https://old.reddit.com/r/Coronavirus/comments/rxecpc/uk_evidence_on_face_masks_in_schools_inconclusive/14:39
BrainstormNew from r/Coronavirus: Coronavirus: The Remarkable Evolutionary Plasticity of Coronaviruses by Mutation and Recombination: Insights for the COVID-19 Pandemic and the Future Evolutionary Paths of SARS-CoV-2 → https://old.reddit.com/r/Coronavirus/comments/rxeny7/the_remarkable_evolutionary_plasticity_of/14:49
BrainstormNew from r/Coronavirus: Coronavirus: Taiwan's domestic COVID airport cases climb to eight; fifth hotel cluster reported → https://old.reddit.com/r/Coronavirus/comments/rxetpa/taiwans_domestic_covid_airport_cases_climb_to/14:58
BrainstormUpdates for Switzerland: +25595 cases (now 1.4 million), +24 deaths (now 12405), +96512 tests (now 14.7 million, 26.5% positive) since 17 hours ago — Croatia: +9058 cases (now 745544), +33 deaths (now 12764), +19975 tests (now 3.8 million, 45.3% positive) since 17 hours ago [... want %more?]15:06
BrainstormNew from Contagion Live: Mix-and-Matching COVID-19 Vaccinations: A panel of doctors explains whether or not someone can get a different COVID-19 booster from their original vaccinations and how they compare. → https://www.contagionlive.com/view/mix-and-matching-covid-19-vaccinations15:08
BrainstormNew from New Scientist: Covid-19 news: Omicron cases hit record highs in Europe: The latest coronavirus news updated every day including coronavirus cases, the latest news, features and interviews from New Scientist and essential information about the covid-19 pandemic → https://www.newscientist.com/article/2237475-covid-19-news-omicron-cases-hit-record-highs-in-europe/15:27
BrainstormNew from StatNews: Pharma: STAT+: Pharmalittle: More top hospitals aren’t offering Biogen Alzheimer’s drug; Pfizer may lower Covid pill price in poor countries until supplies rise → https://www.statnews.com/pharmalot/2022/01/06/covid19-alzheimers-pfizer-biogen-covax/15:36
BrainstormNew from r/Coronavirus: Coronavirus: Omicron hasn't stopped the jobs recovery -- yet → https://old.reddit.com/r/Coronavirus/comments/rxg2gx/omicron_hasnt_stopped_the_jobs_recovery_yet/15:55
BrainstormUpdates for Bosnia and Herz.: +3649 cases (now 297333), +51 deaths (now 13568) since 18 hours ago — Iraq: +665 cases (now 2.1 million), +3 deaths (now 24194), +13153 tests (now 16.9 million, 5.1% positive) since 18 hours ago — Namibia: +460 cases (now 151000), +14 deaths (now 3686), +2282 tests (now 881231, 20.2% positive) since 18 hours ago16:02
BrainstormNew from r/Coronavirus: Coronavirus: Kingston top doc cautiously optimistic, but says hospitalizations remain high → https://old.reddit.com/r/Coronavirus/comments/rxgqd3/kingston_top_doc_cautiously_optimistic_but_says/16:25
BrainstormNew from r/Coronavirus: Coronavirus: Omicron cases are exploding. Scientists still don’t know how bad the wave will be. → https://old.reddit.com/r/Coronavirus/comments/rxgyh9/omicron_cases_are_exploding_scientists_still_dont/16:35
BrainstormNew from r/Coronavirus: Coronavirus: Japan Criticizes U.S. Response After Omicron Spreads Near American Bases → https://old.reddit.com/r/Coronavirus/comments/rxh6s8/japan_criticizes_us_response_after_omicron/16:44
BrainstormNew from Politico: Belgium holds off on new coronavirus measures: But the COVID-19 situation will 'get worse before it gets better,' says Prime Minister Alexander De Croo. → https://www.politico.eu/article/belgium-hold-coronavirus-measures-omicron/16:54
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): The remarkable back story of how @CDCDirector pushed the shortened isolation guidance without testing and without support of key leaders nytimes.com/live/2022/01/0… by @SharonLNYT @SherylNYT @noahweiland pic.twitter.com/snmDUVG7eC → https://twitter.com/EricTopol/status/147912052884559462417:04
BrainstormUpdates for Serbia: +9122 cases (now 1.3 million), +19 deaths (now 12850), +27290 tests (now 7.3 million, 33.4% positive) since 20 hours ago — Denmark: +49353 cases (now 929647), +27 deaths (now 3349) since 20 hours ago — Azerbaijan: +584 cases (now 619502), +13 deaths (now 8422) since 20 hours ago [... want %more?]17:11
BrainstormNew from StatNews: STAT+: Institutional investors urge pharma boards to tie executive compensation to global Covid vaccine equity: "Any board that listens to its shareholders and is conscious of the enormous impact of the current pandemic should take this topic seriously," said [... want %more?] → https://www.statnews.com/pharmalot/2022/01/06/covid19-vaccine-pfizer-jnj-moderna-compensation/17:23
-Bridgestorm- ⭕ Temblor! Sismo! Earthquake! 6.1 Mwp tremor, registered by 5 agencies, with 14 reports, 3 early, occurred 18 minutes ago (16:25:10 UTC), during daytime, Near Coast Of Nicaragua (11.96, -87.17) ± 6 km, ↓34 km likely felt 330 km away (in Masaya, Managua…) by 3.8 million people — Webcams: https://www.windy.com/webcams/1478406061 https://www.windy.com/webcams/1448543715 https://www.windy.com/webcams/1503156723 (www.seismicportal.eu)17:43
-Bridgestorm- ⭕ Temblor! Sismo! Earthquake! 6.2 Mw tremor, registered by 7 agencies, with 14 reports, 3 early, occurred 24 minutes ago (16:25:08 UTC), during daytime, Near Coast Of Nicaragua (11.97, -87.18) ± 3 km, ↓28 km likely felt 340 km away (in Masaya, Managua…) by 3.8 million people — Webcams: https://www.windy.com/webcams/1478406061 https://www.windy.com/webcams/1448543715 https://www.windy.com/webcams/1503156723 (www.seismicportal.eu)17:49
BrainstormNew from r/Coronavirus: Coronavirus: Israel rolls out Pfizer covid pill, using digital health records to identify those most at risk → https://old.reddit.com/r/Coronavirus/comments/rxiljp/israel_rolls_out_pfizer_covid_pill_using_digital/17:52
BrainstormUpdates for Chile: +3112 cases (now 1.8 million), +30 deaths (now 39207), +74438 tests (now 27.7 million, 4.2% positive) since 20 hours ago — Kenya: +2336 cases (now 306686), +7 deaths (now 5411), +10558 tests (now 3.1 million, 22.1% positive) since 20 hours ago — Sri Lanka: +1134 cases (now 590063), +28 deaths (now 15083) since 20 hours ago [... want %more?]18:01
BrainstormNew from r/WorldNews: worldnews: Triple anticoagulant treatment successful in treating long COVID → https://old.reddit.com/r/worldnews/comments/rxivcx/triple_anticoagulant_treatment_successful_in/18:01
BrainstormNew from r/Coronavirus: Coronavirus: NC hospitals say 100% of COVID-19 patients on ventilators are unvaccinated :: WRAL.com → https://old.reddit.com/r/Coronavirus/comments/rxizzt/nc_hospitals_say_100_of_covid19_patients_on/18:11
xxpeople really seem to overload the term 'long covid'18:14
xxsome view that as "covid for 30 days" and others view it as "lasting effects after 180 days or 360 days"18:14
BrainstormNew from BBC Health: Covid: Anti-vaccine campaigns are mumbo jumbo, says PM: Boris Johnson says it is time for him to call out those spreading false information on Covid jabs. → https://www.bbc.co.uk/news/uk-5989849818:21
LjLxx: if by people you mean different studies using that term...18:25
LjL'Cause it's been defined as any and all of those things18:26
LjLDenmark: +49353 cases (now 929647)  yikes18:28
LjLThey have 5.8 million people...18:28
LjL%cases denmark18:28
BrainstormLjL: Denmark has had 929647 confirmed cases (16.0% of all people) and 3349 deaths (0.4% of cases; 1 in 1739 people) as of an hour ago. 109.2 million tests were done (0.9% positive). 4.8 million were vaccinated (82.6%). +49353 cases, +27 deaths since 20 hours ago. See https://offloop.net/covid19/?default=Denmark&legacy=no18:28
LjLBut that CFR...18:29
LjL"[Boris Johnson] said some 30-40% of the 17,000 patients in hospital with Covid "haven't actually been vaccinated at all". This is "increasingly true" of those in intensive care, added Mr Johnson, as the "overwhelming majority of them have not been boosted"."18:40
LjLWhy do these numbers in the UK always seem kinda less impressive than what I hear from the US or elsewhere?18:40
BrainstormNew from r/Coronavirus: Coronavirus: Omicron could boost waning immunity, blood tests show → https://old.reddit.com/r/Coronavirus/comments/rxjt0p/omicron_could_boost_waning_immunity_blood_tests/18:40
LjLThe US in particular has fewer vaccinated people but that doesn't explain other places, unless I just have bad data in mind18:40
LjL(Like thinking of hospitalized people when it's really about "severe" or ICU)18:41
BrainstormNew from r/Coronavirus: Coronavirus: WHO: Record weekly jump in COVID-19 cases but fewer deaths → https://old.reddit.com/r/Coronavirus/comments/rxk0j7/who_record_weekly_jump_in_covid19_cases_but_fewer/18:50
xxI'm more worried about the implication that 60-70% of patients in hospitals *have* been vaccinated18:53
tempateUntil when are you contagious if you have omicron?18:53
xxtempate: until your body clears the virus, best to verify using a proper test. Personally I'm not comfortable giving a statement like "after 5 days from infection you're no longer infectious"18:54
tempatexx: there are many people who keep testing positive even weeks after they first had symptoms, so testing is probably not the best measure18:55
xxtempate: PCR tests?18:56
tempateI don't know about PCR tests18:56
BrainstormUpdates for Italy: +219430 cases (now 7.0 million), +198 deaths (now 138474), +1138310 tests (now 145.5 million, 19.3% positive) since 21 hours ago — Greece: +33711 cases (now 1.4 million), +70 deaths (now 21185), +420227 tests (now 49.5 million, 8.0% positive) since 21 hours ago [... want %more?]19:04
LjLxx: but it's just not consistent with the data I have in Italy or what I've heard about the US19:06
LjLOne thing I suspect is it may be partly due to AZ use, but, hey, they have their own studies that it's even better than mRNA19:07
xxit's yet again horrible how that element of "can we actually trust what they are saying" is entering the equation :(19:07
xxof course they'd like AZ to be awesome19:08
BrainstormNew from StatNews: 3 fatal rabies cases in U.S. suggest public underestimates infection risks: A man in Illinois who was exposed to a bat was counseled repeatedly to take a rabies vaccine. He declined — and later died. → https://www.statnews.com/2022/01/06/rabies/19:09
LjL...19:16
xxrabies is 100% lethal without the vaccine19:18
xxI don't think we know a more lethal pathogen19:19
de-factoin such a case stupidity is 100% lethal19:25
BrainstormNew from r/WorldNews: worldnews: Philippines' Duterte threatens unvaccinated people with arrest → https://old.reddit.com/r/worldnews/comments/rxkyr0/philippines_duterte_threatens_unvaccinated_people/19:28
de-factobeing bitten by a bat, why capture it to bring it in for analysis if declining the implications or the result turning out positive (stats clearly show 100% lethal outcomes without the offered treatment including rabies vaccination)?19:30
xxvoluntary extinction I guess19:31
xxso I don't mind19:31
TuvixFrom one of the BBC articles above, "In the UK, 90% of over-12s have now had at least one dose of a Covid vaccine.", meanwhile in my state in the US, 52.2% of 12-17 teenagers are fully vaccinated, and just 14.5% of 5-11 year old children.19:32
TuvixNot even this state's 65+ population is 90% here, only 81.9%.19:33
de-facto.title https://www.youtube.com/watch?v=W4Or8saWdxY19:33
Brainstormde-facto: From www.youtube.com: The most terrifying virus | Vincent Racaniello and Lex Fridman - YouTube19:33
de-factoVincent Racaniello (the host of TWIV) talking about rabies being the most terrifying virus and how we can fight it very efficiently by vaccination (even after exposure) and lowering prevalence in wild animals19:37
xxI would have died as a child if not for the rabies vaccine19:39
generathat's Tollwut?19:39
de-factoyep19:40
xxairbies would also be a fun disease19:42
xxprobably as destructive to the Arby's business as corona has been to corona beer19:43
BrainstormNew from r/Coronavirus: Coronavirus: France now has over 200,000 new coronavirus cases on average per day → https://old.reddit.com/r/Coronavirus/comments/rxlcr8/france_now_has_over_200000_new_coronavirus_cases/19:47
xx299M total19:49
de-factodamn19:49
xxwhich means my prediction of 300M total cases by end of 1st week of 2022 will be right19:50
de-factoreal prevalence will be N-fold of that with some single digit N19:51
de-factoN>1 for sure19:51
xxsure, but we have to go with some number, and I picked the number of confirmed cases19:51
de-factoafaik in Germany estimates are N ~ 2-319:52
de-factofor current incidence, not sure how Omicron will change that19:52
xxit will be a sentence for the history books "In 2 years, between 7th Jan 2020 and 7th Jan 2022, there were 300M confirmed cases of world corona one"19:52
TuvixDeaths too, especially if we consider the incident "excess deaths" figure, though the factor won't be quite as large for countries with reasonably accurate and ethical death reporting procedures (ie: most modern 1st/2nd world countries)19:52
de-factothat video raising a fascinating point: what if a virus could change the behavior of its hosts to increase its reproduction?19:54
xxalready happens with cat owners19:55
de-factojust think about it, what if a variant of COVID could change the brain hence behavior of infected to become really rebellious and hard to contain19:55
de-facto(not saying that is the case, just what IF it would become the case)19:55
BrainstormNew from r/Coronavirus: Coronavirus: Airlines cancel another 1,600 flights, citing worker coronavirus cases → https://old.reddit.com/r/Coronavirus/comments/rxll7s/airlines_cancel_another_1600_flights_citing/19:57
de-factothat would be a major reproduction advantage of such a variant, especially if hosts were unaware of that its a virus changing their behavior by infecting their brains and re-balancing their neurotransmitters or such19:58
* de-facto shudders19:58
de-factohopefully that never happens19:58
critrit would be hard to measure.19:58
lastshellI felt better today, heart rate is more on my range20:00
BrainstormUpdates for Mozambique: +3301 cases (now 203241), +15 deaths (now 2065), +8143 tests (now 1.1 million, 40.5% positive) since 22 hours ago — Montenegro: +2960 cases (now 183220), +7515 tests (now 1.0 million, 39.4% positive) since 22 hours ago — Maldives: +304 cases (now 97050) since 22 hours ago20:00
Tuvixde-facto: Did you see the UK Biobank brain-imaging preprint study? I was curious if you had an opinion on how notable the finding of the thalamus volume in the pre-COVID scans seem to have the same correlation as seen with the infected vs. control group.20:01
lastshellsporadic coff and sneeze, yesterday I felt tired but not like when you workout20:01
generagood20:01
de-factoTuvix, yes have seen it, we discussed it here20:01
lastshellI been following this https://www.rusticfix.com/covid-19-care/omicron-symptoms-and-how-to-treat-them-at-home/20:03
lastshellfor my own treatment20:03
TuvixWhile they didn't conclude that it really was a predictor, I found the correlation finding rather interesting, which suggests a certain subset of the population may be more intrinsicly vulnerable to infection short of known comorbidities.20:03
de-factothough i am not sure how early that would change the behavior, e.g. if still in infectious phase giving a variant with increased impact on that an reproductive advantage or if it more is like a reaction of the immune system later on20:03
de-factoTuvix, indeed i think the impact on the brain of COVID is largely underestimated, also possibly some auto-immune reactions with epitopes on neuro-tissues20:04
de-factoah yeah now i remember what you mean20:05
TuvixYea, I just read about that today too, with certain antibodies having bad reactions with certain brain tissue. There was a study in rodents (IIRC?) that linked immunoglobin to a possible reduction, though more study is needed to see the impact and obviously side-effects of such treatments.20:06
de-factoalso there are findings of T-cells infiltrating brain tissue, thats very bad20:06
TuvixThis sounds somewhat similar to the cytokine storm that was discussed early on in the pandemic, but a far more localized understanding of how it impacts tissue past the blood/brian barrier.20:06
de-factofor covid cases20:06
BrainstormNew from r/Coronavirus: Coronavirus: South Africa COVID-19 Update January 6: 9,860 Cases and 551 deaths → https://old.reddit.com/r/Coronavirus/comments/rxlnsh/south_africa_covid19_update_january_6_9860_cases/20:07
de-factobut i guess that all happens later, not in the infectious phase20:07
de-factoimpact on pathogen reproduction would have to happen during the phase where infected still have the capability to infect others20:07
lastshellhow long I need to be in quarentine for omicron if i starting to feel good ?20:09
Tuvixlastshell: Most of that article is highly dubious since the preprints linked in the "studies" citied do not show any clinical improvement in outcomes, only some enzyme-based approaches that aren't going to be relevant.20:10
TuvixAbout the *only* good advice that article has is that you should get vaccinated/boosted once you've recovered, if you're not already or when you are eligible.20:11
lastshellI'm vaxxed and booster20:11
lastshelland still got omicron20:11
TuvixYea, break-through cases are more common with omicron both due to slightly lower protection against symptomatic infection than in delta & earlier, but also the insane spread.20:12
TuvixVaccination still reduces the odds of really nasty outcomes, like being on a vent, so that's the good news.20:12
lastshellquestion is now with 3 jabs and omicron infection I will have enough imunity for the next varians ?20:13
TuvixAnd I'm not saying the herbs or whatever will hurt, but it's not a way to "prevent" infection. Although fluids are usually good, so if anything else, tea and other mixtures are likely helping regardless.20:13
de-factodid you test positive lastshell ?20:14
lastshellyes de-facto last tuesday, I starting to sneeze since sunday and monday some sore-troat20:14
Tuvixlastshell: So, the reality is we just don't know yet, and we haven't seen the next-varient. It could be much different (like Omicron was, compared to delta & the others) or it could be a smaller change. It's hard to predict the future.20:14
lastshellmy heart rate starting to normalize now20:14
lastshellbut was a little odd first days20:15
de-factowas it elevated heart rate?20:15
lastshellslow walking for me is general 70-80 range20:15
lastshellwas 90-10020:15
de-factodid you had a fever?20:16
lastshellno fever20:16
de-factointeresting20:16
lastshellbut I use the heater20:16
lastshellsometimes i feel cold other hot20:16
lastshellput and remove blanquets20:16
lastshelland I sweat over night20:16
BrainstormNew from StatNews: STAT+: Chilean health ministry is urged to issue a compulsory license for the Pfizer Covid pill: In the latest bid to expand access to the Pfizer Covid-19 pill, a nonprofit group and an association of pharmacists are seeking to make it possible for generic [... want %more?] → https://www.statnews.com/pharmalot/2022/01/06/pfizer-covid-paxlovid-chile-pandemic-coronavirus/20:16
de-factoyeah, i read that this is one thing that potentially may be more prevalent in omicron infections20:16
TuvixAs for how long you remain infectious, that can vary, but by 10 days after testing positive, only 5% of people continue to test as infectious: https://imgur.com/4W0x7xA20:17
de-factonight sweating, with the necessity to change sheets20:17
de-factois that Omicron Tuvix ?20:17
lastshellI also ventilate the room20:18
lastshellbut is cold where i am so I wait for mid day20:18
lastshellto do it20:18
TuvixThe best measure would be to take a couple of rapid antibody tests 3 to 5 days once you're no longer feeling symptoms, but remember the rapid antigen tests, in particular the at-homes ones, have a rather notable false-negative rate (they can read negative when you're actually positive.)20:18
lastshellok20:18
lastshellis safe togo to buying groceries with 3m aura mask or is better to order to house food ?20:19
lastshellI don't want to spread this20:19
TuvixCDC's guidance which seems reasonable here, calls this "isolation" and on that topic says: "Isolation is used to separate people with confirmed or suspected COVID-19 from those without COVID-19. People who are in isolation should stay home until it’s safe for them to be around others. At home, anyone sick or infected should separate from others, or wear a well-fitting mask when they need to be around20:20
Tuvixothers."20:20
de-factolastshell, drink green tea during daytime, small sips over extended period of time, but only normal amounts20:20
de-factoit covering the surface of your mucus may inactivate virions that happen to be there20:21
lastshellok20:21
lastshellthank you guys for all the advices20:21
TuvixYou should do your best to avoid social contact with others, but if you absolutely have to go out, I'd wear a quality mask and be sure to do a good fit-test. No mask is perfect, but a poorly worn one will leak more air, and the risk is that a symptomatic individual in the 5-to-10 days after infection (or while remaining symptomatic or with positive antigen results) is likely still infectious.20:22
lastshellhonestly wans't that bad for me20:22
lastshellmy mom is experience more tireness than me and body aches20:22
TuvixAnd yea, being vaxed+boosted sounds like it probably helped reduce your symptoms, and that's how you want to face COVID if you have to get it.20:22
lastshellshe is also 3x vacced20:22
lastshellim glad that we had the 3 shots20:23
TuvixObviously not getting it is better, but that's just not a practical reality to expect in these times, even with the best of protection measures.20:23
lastshellwe use n95 masks and lisol and everythin we avoid covid for 2 years until now :(20:23
TuvixYea, it's rough, you can do everything right and still be exposed. It's also possible your protection measures like masking around other groups outside of your hosehold reduced the "viral load" meaning exposed you to a smaller amount of virus. That can help, to a point too.20:24
TuvixMitigation is like layers on an onion, but it sounds like you and your family member didn't have severe outcomes, and that's exactly what the vaccines are designed to do. Lowering case-incidence a bit is a bonus, but that protection isn't as high. Especially not with Omicron…20:25
BrainstormNew from CIDRAP: Persistent COVID-related loss of taste may be overestimated: Mary Van Beusekom | News Writer | CIDRAP News Jan 06, 2022 A study by Italian researchers found only 42% of COVID patients had impaired sense of taste 7 months after infection. → https://www.cidrap.umn.edu/news-perspective/2022/01/persistent-covid-related-loss-taste-may-be-overestimated20:26
TuvixLast night I was listening to emergency medical dispatch here, and a 40-something was having trouble breathing after testing positive for COVID. They don't announce vaccination status for those over the air (not relevant for the medic) but _that_ is the kind of outcome we all really want to avoid.20:27
de-factowhere is that?20:28
TuvixThe dispatch? Wisconsin, US.20:28
de-factoah ok how is Omicron wave doing there?20:29
TuvixThe state just a few days ago published a public notice (which lots of the vax/mask resistant won't read anyway) indicating that hospitals are already strained from both the long tail of the Delta wave here and seasonal respiratory viruses; compounding that, the lab at the time was only showing about 50% Omicron cases in COVID-positive, so the peak is probably still another 1-to-3 weeks out, at least.20:30
de-factohttps://www.dhs.wisconsin.gov/covid-19/cases.htm <-- nice dashboard btw20:31
TuvixOurs is one of the states who has received some federal help with medical staffing due to the high capacity many of the hospitals are running at. As of the mid-week update, all hospitals in my region of the state report ICUs operating at peak capacity, though there's a _small_ bit over overhead still in the non-ICU beds.20:31
TuvixYea, the dashboard is decent, but the update frequency kind of stinks for some of the metrics.20:31
TuvixThis only updates weekly on Wednesdays with 2-week snapshots, but the outlook hasn't been great basically since the peak of delta: https://www.dhs.wisconsin.gov/covid-19/hosp-data.htm20:32
de-factoi live in BW Germany, we just have the first rise in cases again, so Omicron wave about to take off20:32
TuvixWe've seen a pretty long tail on Delta here, and frankly nation-wide.20:32
TuvixHow are hospitals doing there, regionally?20:33
TuvixThe surge is hitting lots of places, but rather than raw case numbers I find evaulating the healthcare critical system a better mettric of impact to the seriously-ill.20:33
de-factoslightly falling case numbers in hospital and ICU due to Delta wave declining20:34
de-factotoo early for any Omicron based severe progressions yet i guess20:34
TuvixAh, so that's probably a better start than we had here in this state; that page I linked does show a dip around mid-October, but it never really got back to anything near pre-Delta levels.20:34
de-factohttps://www.intensivregister.de/#/aktuelle-lage/zeitreihen20:34
TuvixThen it rose up again in advance of all the holiday travel :\20:34
de-factoyes in Germany it will soon be pure Omicron most likely20:35
BrainstormNew from StatNews: Scientists try to pinpoint why rapid Covid tests are missing some cases: Scientists are trying to determine why rapid Covid tests are missing cases, many of them of the Omicron variant, and what can be done about it. → https://www.statnews.com/2022/01/06/scientists-try-to-pinpoint-why-rapid-covid-tests-are-missing-cases/20:35
de-factobecause Delta (was) and still is on decline and measures most likely will be increased soon to flatten the Omicron peak, hence flatten the less reproductive Delta peak even more simultaneously20:36
TuvixOh, yea, so you had a similar dip, but not a big one either for the Okt fall. The dip into this year is more pronounced, although maybe those cases just haven't been reported?20:37
TuvixI guess it follows trends from prior peaks, so maybe that was a post-holiday impact too.20:37
TuvixOur death rate never really fell after Delta started to decline from the worst of the surge nationally here, not like it did back in late-spring to mid-summer: https://covid.cdc.gov/covid-data-tracker/#trends_dailycases_7daydeathsper100k20:38
TuvixDelta kind of dragged on for a while not really reducing the death rate as sharply as we saw with the prior strains, but it's back on the rise again and we've really only started to see the Omicron impact.20:39
BrainstormNew from r/COVID19: COVID19: Association between vaccination status and reported incidence of post-acute COVID-19 symptoms in Israel: a cross-sectional study of patients infected between March 2020 and November 2021 → https://www.reddit.com/r/COVID19/comments/rxmxm3/association_between_vaccination_status_and/20:55
BrainstormUpdates for Ireland: +23817 cases (now 908672) since 23 hours ago — Turkey: +134880 cases (now 9.8 million), +299 deaths (now 83231) since 23 hours ago — Luxembourg: +1932 cases (now 110298), +1 deaths (now 921) since 23 hours ago — Burundi: +1475 cases (now 33551) since 23 hours ago21:03
BrainstormNew from r/Coronavirus: Coronavirus: West Virginia wants to administer 4th COVID-19 vaccine dose → https://old.reddit.com/r/Coronavirus/comments/rxn09b/west_virginia_wants_to_administer_4th_covid19/21:05
oerheks West Virginia wants to administer 4th COVID-19 vaccine dose .. while Africa is waiting..21:07
grysomeone asked what happens when governments run out of money for lockdowns and/or vaccines21:07
oerheksgry, see kazakhstan21:08
oerheksThey will destroy services and food distribution, that adds to the unrest21:09
oerheksNo usb port in your tesla, start rioting!21:09
BrainstormNew from r/Coronavirus: Coronavirus: Covid Live Updates: Advisers to Biden Transition Team Call for Entirely New Domestic Covid Strategy → https://old.reddit.com/r/Coronavirus/comments/rxn3rz/covid_live_updates_advisers_to_biden_transition/21:14
LjLthis has nothing to do with COVID, sorry, but it looks like so much of a big deal to me for any computer user who wants to keep a vague sense of owning their computer... and it's being introduced *while* we're all focusing on COVID, and it could be marketed as useful for "supervision" during remote learning and remote working...21:16
LjL%title https://www.reddit.com/r/privacy/comments/rwrz0x/microsoft_to_introduce_chip_to_cloud_security/21:16
BrainstormLjL: From www.reddit.com: Microsoft to introduce chip to cloud "security" with 'remote attestation' based on Xbox DRM, delivered through Windows Update. : privacy21:16
LjLpinging Tuvix and de-facto, not sure off hand who else here is sensitive to these matters21:17
LjLand my comments about it: https://np.reddit.com/r/linux/comments/rwzoas/microsoft_to_introduce_chip_to_cloud_security/hrj96zn/  https://np.reddit.com/r/privacy/comments/rwrz0x/microsoft_to_introduce_chip_to_cloud_security/hrj9gx0/21:18
enycHrrm, fun to be had with Omicron now...21:21
enyccurioust if we will have effective herd immunity as sicrietsts now showing that omicron genuinely milder etc21:21
BrainstormNew from r/Coronavirus: Coronavirus: Up to 80% of FL will have caught COVID-19 by end of omicron wave, UF report says → https://old.reddit.com/r/Coronavirus/comments/rxnnun/up_to_80_of_fl_will_have_caught_covid19_by_end_of/21:24
ArsaneritWhat is sicrietsts?21:26
Tuvixenyc: That depends a lot on how effective that is, and what the future brings. Re-infection is a thing, and prior varients do not appear to be nearly as protective against Omicron when compared to earlier versions.21:27
TuvixIt's still crucial for the unvaccinated to get vaccinated, even if they've been antigen or PCR positive, or else it's quite possible we just keeping seeing a significant number of re-infections, and the outcomes are not as clear for those people (it would be nice to see more studies here, but it's hard becuase many of thsoe refusing vaccines are also not the kind of people to be interested to show up in21:29
Tuvixhigh-quality studies)21:29
BrainstormNew from r/Coronavirus: Coronavirus: COVID-19 may have killed nearly 3 million in India, far more than official counts show → https://old.reddit.com/r/Coronavirus/comments/rxnr9i/covid19_may_have_killed_nearly_3_million_in_india/21:34
BrainstormNew from r/WorldNews: worldnews: Calling Omicron 'mild' a mistake, warns WHO → https://old.reddit.com/r/worldnews/comments/rxo3ly/calling_omicron_mild_a_mistake_warns_who/21:43
TuvixLjL: That kind of attestation only works if the end-user has a way to know it's enabled _and_ turn it off (and have it STAY off) if they're the equipment owner. If it's a company-owned PC and they want some attestation, fine (entiere software suites are built around this idea today already) but if I can't stop it on hardware I own, that's bad. I'd assume that would be the result, but that's obviously21:47
Tuvixunclear.21:47
LjLTuvix, well, i "can" stop SafetyNet stuff on Android right now for instance, but if i do (by installing a custom ROM, enabling root, just unlocking the bootloader, or other things, since it has "nuances" where apps can decide what's too much) then i become unable to use not just Pokémon Go, which i can definitely do without, but also banking apps, or the app that lets me check the least congested ERs in my area (yes, the one for Lombardy refuses to work if you're21:49
LjL rooted!), or things that may be actually pretty close to being government requirements to have installed (the Io or Immuni apps)21:49
LjLso i think just giving the option of disabling this stuff doesn't calm my fears, because "everything" may become unusable if you disable it, if "everything" starts happily making use of it as it finds it can restrict you better by requiring it21:49
LjLi can refuse to use Netflix, which i do, and then other things, but at some point when i can't use things that are nearly mandatory, i have to give up21:50
Tuvixyea, it only really works, IMO, when it's actually opt-in, and by equipment owners, not app developers.21:50
TuvixI disagree a bit with the idea that "this OS hasn't been tampered with" and "we can attest and monitor what you have done on your OS such as config, programs installed, and all this other stuff"21:51
LjLa bit, eh21:51
TuvixIt's perfectly reasonbale for something like a banking app (IMO) to decide they want to vet the OS is authentic, but NOT for my bank to know what apps I do/don't have installed.21:51
TuvixDoes knowing how to use a browser DOM debugger make me a threat to my bank? My use of system analysis tools? `strace` on Linux? etc.21:52
LjLyeah you know maybe it should just be designed as secure and then some responsibility should still be on the end user, rather than dumbing it all down by making my computer their terminal21:52
TuvixBy "vet the OS is authentic" I mean use a limited API call to do it, not be able to run arbitrary code to determine that, to be clear :P21:53
LjLexcept a terminal with a microphone, a camera, other sensors, and tons of my other apps and pages and stuff21:53
BrainstormNew from ##covid-19 Zotero group: Newsnodes: Type Web Page URL https://newsnodes.com/ Accessed 2022-01-06 20:44:40 Abstract : COVID-19 edition → https://www.zotero.org/groups/covid_links/items/K9ITREXB21:53
TuvixAnd yea, sneaking this stuff in during COVID or holidays is just silly, if it's meant to burry the news.21:53
LjLTuvix, it still requires a pretty full chain of trust to do that, though, which seems like *at best* a huge waste of resource to just say "yep, the user didn't compile his own OS"21:53
LjLand at worst, it will interfere with my ability to use the device the ways i want even when i'm not actually using the banking app or anything21:54
LjLmaybe banks should give us their own terminals if they care so much they are untampered with, and so should governments21:54
LjLbut then again... some car insurers to that, and their terminals that you have to keep in your car also have a microphone, sensors, etc -.-21:55
LjLokay just going slightly back on topic, as usual, the WHO is right on time on the ball, LOL <Brainstorm> New from r/WorldNews: worldnews: Calling Omicron 'mild' a mistake, warns WHO → https://www.reddit.com/r/worldnews/comments/rxo3ly/calling_omicron_mild_a_mistake_warns_who/21:55
BrainstormUpdates for Morocco: +6050 cases (now 983629), +11 deaths (now 14883), +33276 tests (now 11.0 million, 18.2% positive) since a day ago21:59
BrainstormNew from Johnson&Johnson: Innovation: Real World Evidence Shows Johnson & Johnson COVID-19 Vaccine Demonstrates Durable Protection Against Breakthrough Infection, Hospitalization, and Intensive Care Unit [... want %more?] → {"param":"apiKey","title":"Invalid authorization","type":"INVALID_AUTHORIZATION","status":401,"detail":"Expected authentication to be provided in \"apiKey\" query param"}22:12
oerheksLjL api key expired?22:16
LjLoerheks, oh the API never works (or rather i call it wrong) but it's actually not supposed to print that but it does sometimes22:16
LjLi'll have a look after dinner22:17
LjLmaybe22:17
aradeshboris saying something i agree with for once: https://www.bbc.co.uk/news/uk-5989849822:31
BrainstormNew from StatNews: Listen: Biotech in 2022, the Omicron surge, & the Elizabeth Holmes verdict: How worrisome is Omicron? Are the vibes off in biotech? And does the Theranos verdict really matter? All that and more on the new episode of "The Readout LOUD." Listen… → https://www.statnews.com/2022/01/06/podcast-biotech-2022-omicron-surge-elizabeth-holmes-verdict/22:31
aradeshthat anti-vaxxers spout mumbo-jumbo22:32
aradeshwhen i look at our government, i see a government who wants to avoid lockdowns at all costs.. basically acts at the last possible minute, and does as little as it can. boris saying things like, "the NHS will be under pressure but will have to get through it" and govt. science advisors saying, "we can't keep vaccinating people forever" --- whereas the antivaxxers/lockdown-campaigners make it out that the22:34
aradeshgovernment is gleefully keeping the country under lock & key for fun, and that it wants to vaccinate us forever22:34
aradeshsoudns like he's finally discovered anti-vax social media propaganda22:35
aradeshoh, also the anti-vaxxers here say the government wants to mandate everyone to have the vaccine, whilst the PM keeps saying he wants to keep it voluntary22:36
BrainstormNew from CIDRAP: Global COVID-19 cases, driven by Omicron, up sharply: Lisa Schnirring | News Editor | CIDRAP News Jan 06, 2022 Cases are up in all world regions, especially the Americas and Southeast Asia, leading to the pandemic's highest daily totals. → https://www.cidrap.umn.edu/news-perspective/2022/01/global-covid-19-cases-driven-omicron-sharply22:41
critrunfortunately, this is the age of massive, well-funded, long-term lie campaigns.22:43
aradeshliterally people living in alternate realities22:45
critrindeed.22:45
BrainstormNew from CIDRAP: Experts call on Biden administration to change pandemic plan: Stephanie Soucheray | News Reporter | CIDRAP News Jan 06, 2022 Authors include some members of Biden's COVID-19 transition team, who push for a long-term approach. → https://www.cidrap.umn.edu/news-perspective/2022/01/experts-call-biden-administration-change-pandemic-plan22:50
aradeshi find it a real curiosity. i don't blame most people who end up falling for the conspiracies, because... if you live in an echo chamber where all you hear is an alternate reality, you believe the alternate reality22:53
aradeshthe people who create the fake propaganda and push this stuff for profit though, are evil.22:54
br41n5t0rmI think many ppl are also doing very hard filtering the correct informations. aradesh22:55
lastshellsilly question I assume is ok to take a hot shower when you have covid ?22:55
br41n5t0rmXD22:56
aradeshdon't see why not. if you have a bad fever though, might not be a good idea to have one too hot22:56
lastshellno fever so far22:57
aradeshget well soon22:57
lastshellmaybe lukewarm watter not for me my mom thanks aradesh22:57
aradeshbr41n5t0rm: yes. and some people ahve a personality type that they tend to believe conspiracies, they can't help that.22:57
br41n5t0rmtrue22:58
aradeshif you already believe the government lies to us about everything, very easy to fall into new holes22:58
aradeshi dunno if this is true - but apparently negative reviews of yankee candles having no smell coincides with cases of covid in the USA lol https://www.youtube.com/watch?v=caskghNtLwQ22:59
br41n5t0rmi think the best way to inform is to get for example the statistics at qualified sources. Can be scientific papers or by institutes directly22:59
br41n5t0rmof course there are also additional ways. dependent on the subject22:59
br41n5t0rmlol aradesh23:00
BrainstormNew from r/Coronavirus: Coronavirus: "It's Not Sustainable": NYC Public School Administrators, Teachers Struggle With Staffing Shortages → https://old.reddit.com/r/Coronavirus/comments/rxpsgu/its_not_sustainable_nyc_public_school/23:00
critrin general, i think people with cognitive deficits tend to cling to paranoid ideation to reduce anxiety. and they're very easy to manipulate.23:00
de-factolastshell, as long as it does not raise your heart rate too much23:02
de-factoid stay on the "normal" temp and duration just not to challenge your BP and P too much23:03
de-factoand maybe eat something in advance so you got enough blood sugar23:03
aradeshP = pulse?23:04
de-factoyep sorry23:08
de-factobasically what i meant is not to stress the circulation system too much, but stay mobile to prevent thrombosis23:08
de-factomoderate movement without too much stress is best i guess23:08
critrrocking chair ftw.23:09
de-factogoing for a calm walk, not for a run, going for normal shower not extra hot etc23:09
BrainstormNew from r/Coronavirus: Coronavirus: Lack of high school education predicts vaccine hesitancy → https://old.reddit.com/r/Coronavirus/comments/rxpvje/lack_of_high_school_education_predicts_vaccine/23:09
lastshellshe has a seat23:11
lastshellthank you de-facto23:11
de-factobut again, a bit movement may be required, afaik in hospitals, when people stay in bed the whole day their risk of developing a thrombosis originates just from lack of mobility23:12
lastshellI noticed my hear rate is way normal this day than before23:12
de-factonice, yeah drink enough, keep your blood thin23:13
lastshellyeah we drinking pleany of water and sometimes warm gold milk (tumeric with milk almond)23:13
lastshellapprox how long does omicron stay in the body ?23:14
BrainstormUpdates for North Macedonia: +1725 cases (now 230265), +2 deaths (now 8002), +7472 tests (now 1.6 million, 23.1% positive) since a day ago — Kuwait: +2413 cases (now 425455), +27541 tests (now 6.1 million, 8.8% positive) since a day ago — Mauritania: +1179 cases (now 45825), +4 deaths (now 880), +4995 tests (now 584297, 23.6% positive) since a day ago [... want %more?]23:14
BrainstormNew from Reddit (test): 'Flurona' is just a new buzzword, not new strain of COVID-19 or new phenomenon: 'cuz Reddit doesn't think the URL is a URL, below a text copy starting with the link may be found. Recommend visiting the link as the full and complete article contains links [... want %more?] → https://old.reddit.com/r/nCoV/comments/rxqkrv/flurona_is_just_a_new_buzzword_not_new_strain_of/23:19
de-factohard to tell that, i guess if you are vaccinated much shorter compared to non-vaccinated23:24
lastshellvaxxed and boosterized23:25
lastshellI starting to feel better but sore troath continues23:25
de-factobecause your immune system already is "on the wait" so Omicron will have no chance of incognito replication23:25
de-factoyeah drink some green or black tea, no joke23:25
* critr takes tea advice23:28
BrainstormNew from Reddit (test): nCoV: What is ‘flurona’, and should you worry about it during flu season? What experts say | 05JAN22 → https://old.reddit.com/r/nCoV/comments/rxqn6h/what_is_flurona_and_should_you_worry_about_it/23:29
sdfgsdfgwhite chinese oolong tea23:29
sdfgsdfggreen tea really does have good immunity enhancing features he's right23:30
sdfgsdfgnot just that but it increases dopamine as well if I remember right, it's good with neurotransmitters somehow23:31
de-factobut: normal amounts, its hard for the liver to digest the molecules23:33
de-facto.papers tsa23:33
Brainstormde-facto, 10 results out of 36: Different Effects of the COVID-19 Pandemic on Exercise Indexes and Mood States Based on Sport Types, Exercise Dependency and Individual Characteristics by Alireza Aghababa et al, dated 2021-06-03 → https://www.doi.org/10.3390/children8060438 [... want %more?]23:33
de-facto.papers EGCG23:34
Brainstormde-facto, 10 results out of 45: EGCG, a green tea polyphenol, inhibits human coronavirus replication in vitro, dated 2021-02-16 → https://www.doi.org/10.1016/j.bbrc.2021.02.016 — Therapeutic Potential of EGCG, a Green Tea Polyphenol, for Treatment of Coronavirus Diseases, dated 2021-04-04 → https://www.doi.org/10.3390/life11030197 [... want %more?]23:34
de-factonote its not a cure or anything like that, it only MAY possible help a bit23:34
sdfgsdfgwhoa, I like this new .papers command23:34
sdfgsdfgthis is awesome...23:34
de-facto( its not new btw but it surely is awesome, as many things that LjL did :)23:35
LjL=)23:35
LjLwell in turn i only wrote a simple frontend to an API that uuuuh someone else made and i can't even remember whose API i'm using23:35
LjLoutbreak.info now23:36
LjLi think i was using something else before but it went away23:36
LjLby the way there's also like23:36
LjL%vaccine moderna23:36
BrainstormLjL, mRNA-1273 LNPencapsulated mRNA is a RNA-based vaccine developed in USA by Moderna + NIAID + Lonza + Catalent Inc. + BIOQUAL + Baxter BioPharma Solutions , which started distribution initially on January 2021 → https://covidvax.org/covid19-vaccine/Moderna23:36
LjLand you can search through the github, though the github is obsolete by now and i should make it search in the zotero but pyzotero requires things i haven't ported yet23:37
LjLuhmm the only thing i remember that's definitely in the github is also definitely unpleasant23:37
LjL%links intestine23:38
BrainstormLjL, https://www.nature.com/articles/s41586-021-03207-w (Evolution of antibody immunity to SARS-CoV-2) finds that in a cohort of 87 patients 10% of which needed hospital care, 44% reported long-term symptoms after 6 months, and it also suggests that there may still be replicating virus in the intestine (gut) of about half of infected individuals at least 90 days after infection [... want %more?]23:38
BrainstormNew from Reddit (test): nCoV: 1 Symptomatic, 1 Asymptomatic Case Locks Down China City Of 1 Million | 06JAN22 → https://old.reddit.com/r/nCoV/comments/rxr0dq/1_symptomatic_1_asymptomatic_case_locks_down/23:38
de-facto^^ see what i mean ? :D23:42
BrainstormNew from Reddit (test): nCoV: COVID-19 testing policies under scrutiny worldwide as omicron surge drives up demand | 06JAN22 → https://old.reddit.com/r/nCoV/comments/rxr8pf/covid19_testing_policies_under_scrutiny_worldwide/23:48
BrainstormNew from Reddit (test): nCoV: 'Flurona' is just a new buzzword, not new strain of COVID-19 or new phenomenon | 06JAN22 → https://old.reddit.com/r/nCoV/comments/rxra0a/flurona_is_just_a_new_buzzword_not_new_strain_of/23:58

Generated by irclog2html.py 2.17.0 by Marius Gedminas - find it at https://mg.pov.lt/irclog2html/!