| de-facto | .title https://www.biorxiv.org/content/10.1101/2021.02.03.429164v3 | 00:05 |
|---|---|---|
| Brainstorm | de-facto: From www.biorxiv.org: Ensovibep, a novel trispecific DARPin candidate that protects against SARS-CoV-2 variants | bioRxiv | 00:05 |
| Brainstorm | New from r/WorldNews: worldnews: In Greece, unvaccinated people ages 60 and up now face monthly fines → https://old.reddit.com/r/worldnews/comments/s6hcx3/in_greece_unvaccinated_people_ages_60_and_up_now/ | 00:07 |
| de-facto | .title https://www.molecularpartners.com/pipeline/#anti-covid-19 | 00:17 |
| Brainstorm | de-facto: From www.molecularpartners.com: Pipeline – Molecular Partners | 00:17 |
| de-facto | .title https://www.novartis.com/news/media-releases/novartis-and-molecular-partners-report-positive-topline-data-from-phase-2-study-ensovibep-mp0420-darpin-antiviral-therapeutic-covid-19 | 00:18 |
| Brainstorm | de-facto: From www.novartis.com: Novartis and Molecular Partners report positive topline data from Phase 2 study for ensovibep (MP0420), a DARPin antiviral therapeutic for COVID-19 | Novartis | 00:18 |
| de-facto | "Topline results from the randomized EMPATHY Part A study in acute COVID-19 ambulatory patients comparing single intravenous doses of ensovibep, a DARPin antiviral therapeutic candidate vs. placebo, met the primary endpoint of viral load reduction over eight days" | 00:18 |
| de-facto | "The secondary endpoint of hospitalization and/or ER visits related to COVID-19, or death showed an overall 78% reduction in risk of events across ensovibep arms compared to placebo | 00:18 |
| de-facto | " | 00:18 |
| de-facto | "A total of 407 patients were recruited in the Phase 2 study and ensovibep was safe and well-tolerated at all doses (75mg, 225mg and 600mg) – with 75mg the planned dose for further development" | 00:19 |
| de-facto | "Ensovibep continues to maintain potent in vitro pan-variant activity against all variants of concern identified so far, including Omicron" | 00:19 |
| de-facto | "Ensovibep is a multi-specific DARPin (Designed Ankyrin Repeat Protein), specifically designed to block the receptor binding domains of SARS-CoV-2 spike protein through highly potent and cooperative binding, making it challenging for escape mutants" | 00:19 |
| de-facto | "Novartis confirms it will exercise its option, paying CHF150 million to in-license ensovibep from Molecular Partners, accelerate manufacturing scale-up, and plans to seek expedited regulatory authorizations globally – first via the U.S. Food and Drug Administration’s (FDA) Emergency Use Authorization (EUA)" | 00:19 |
| bleb | how do you interpret this https://i.ibb.co/dbcmgTG/covid.png | 00:23 |
| bleb | I thought it meant positive because of POSITIVE in bold red letters | 00:24 |
| bleb | but its under the "Abnormal" column not the "Result" column | 00:24 |
| bleb | and the first heading is "OUT OF RANGE SUMMARY" so maybe out of range means the test was inconclusive? | 00:25 |
| Brainstorm | New from Ars Technica: Science: Pfizer and Moderna expect seasonal booster shots after omicron wave → https://arstechnica.com/ | 00:26 |
| Tuvix | I'd say it's unclear given both of those things, and would call back the clinic or facility that conducted the test for clarification. | 00:27 |
| de-facto | yeah thats the worst summary of a test result possible, inconclusive to the maximum. call them and ask what they mean by that | 00:29 |
| de-facto | why cant they just write CT value? | 00:30 |
| de-facto | out of range MAY mean CT value, but who knows what they refer to there | 00:31 |
| de-facto | who designs such websites? thats really a very good job to make the result as inaccessible as possible | 00:33 |
| Tuvix | Mine was slightly confusing, but not anywhere near that bad. | 00:34 |
| de-facto | if i had to guess it could mean compared to the "reference: negative" that the "abnormal: positive" maybe out of usual CT range, hence they leave "result" blank | 00:35 |
| de-facto | but then what is the second header? | 00:35 |
| de-facto | if they just would give a single number (CT value) it would give more info as that horrible website there | 00:36 |
| bleb | its a PDF actually | 00:38 |
| de-facto | call them, complain about it and ask what they mean | 00:40 |
| de-facto | they have to change that | 00:40 |
| de-facto | maybe ask them how many cycles they used and what result they found after that number of thermocycles | 00:42 |
| de-facto | then ask them to give you reference values for their pipeline for results "positive" and "negative" | 00:42 |
| de-facto | PCR functions by replicating the DNA from the sample (the throat swab) | 00:44 |
| de-facto | it does so by cycling through some temperature cycles that activates different molecules periodically | 00:45 |
| de-facto | each cycle roughly means doubling the sampling material | 00:45 |
| de-facto | the molecules only fit on specific parts of the SARs-CoV-2 genome, hence only that will get amplified | 00:45 |
| LjL | bleb, i agree that result looks needlessly confusing, but i don't think "POSITIVE" is so much under the "Abnormal" column as just not under any particular column. it looks like those column names are there for a test that's not that one | 00:45 |
| LjL | i would strongly treat that as positive provisionally, and quarantine, until you can confirm | 00:46 |
| de-facto | yeah | 00:46 |
| de-facto | the CT value means how many of such thermo cycles were needed until a detectable amount of material was seen | 00:48 |
| de-facto | if the CT value is below a (pipeline specific) threshold it would mean the result is positive detection of the virus RNA in the sample | 00:48 |
| bleb | ok I figured it was positive too | 01:06 |
| bleb | of course none of the numbers are picking up so will have to try tomorrow | 01:08 |
| LjL | was this done following a positive rapid test? | 01:10 |
| bleb | I did a negative rapid test last sunday, negative PCR test last monday, then this PCR test on wednesday | 01:12 |
| Brainstorm | New from r/Science: science: A proportion of patients develop post-acute COVID syndrome (long COVID). A recent study involving people with long COVID published in the journal Nature Immunology indicates that many people continue to experience immunological dysfunction 8 [... want %more?] → https://old.reddit.com/r/science/comments/s6ip5c/a_proportion_of_patients_develop_postacute_covid/ | 01:23 |
| LjL | test results in one day! another world to here :P | 01:23 |
| LjL | i think even though to me that looks like a positive, if you had all negative results before, you should definitely try to get this one clarified | 01:23 |
| LjL | but when i tried semi-emergency medical services some days ago, it didn't even put me on hold, it just rang busy ;( so i'm not exceedingly surprised they're not picking up the phone | 01:24 |
| sdfgsdfg | I heard austria's mandatory vaccine fines are about 3600 euro | 01:24 |
| sdfgsdfg | and it's kicking in at the beginning of Feb | 01:24 |
| sdfgsdfg | in about 2 weeks | 01:24 |
| LjL | they're €100 here, lol | 01:25 |
| LjL | well, it depends which fine i guess, i've also read something between €600 and €1500 iirc but that was probably something about workers, while the €100 fine is for people over 50 who are the one actually having mandatory vaccination now | 01:26 |
| Tuvix | "up to" €3600 according to this: https://www.politico.eu/article/austrias-vaccination-mandate-to-apply-from-february-1 | 01:26 |
| LjL | in Greece the fine is €100 too, but *per month* | 01:26 |
| Tuvix | "In total, those not complying with the mandate can be fined up to four times a year. A fine will be dropped if the recipient gets vaccinated within two weeks of receiving the penalty notice." | 01:26 |
| Tuvix | Intersting approach. | 01:26 |
| sdfgsdfg | I expect italy and greece will follow by increasing the fine numbers as well | 01:26 |
| sdfgsdfg | same happened in australia | 01:26 |
| sdfgsdfg | and is happening | 01:27 |
| Tuvix | So, if fined, you can decide that it really wasn't worth the risk of getting caught and go get vaccinated after. | 01:27 |
| sdfgsdfg | it's the new thing, it's quite scary for some reason | 01:27 |
| sdfgsdfg | they are going to enforce the following 3rd and 4th doses with these laws | 01:27 |
| sdfgsdfg | it's no joke that it looks like it will continue until 8th dose | 01:28 |
| LjL | damn i wish i could see into the future too | 01:28 |
| dTal | I dunno, hordes of ignorant and unvaccinated people flooding medical services is much scarier to me | 01:28 |
| dTal | and that is what will happen | 01:28 |
| dTal | will happen? is happening | 01:28 |
| sdfgsdfg | it probably looks like the blame is on the unvaccinated still - maybe in europe and usa | 01:29 |
| dTal | on one of my hippy whatsapp groups people are calling mandatory negative covid tests to get into nightlife venues a "hate crime" | 01:30 |
| dTal | no lie | 01:30 |
| Tuvix | US just sent over a hundred medically-trained military staff to a half-dozen states here in the US. | 01:30 |
| dTal | "Years ago their use to be a notice outside pubs ,saying no blacks,no Irish, no travellers etc." | 01:31 |
| dTal | (yes, "their") | 01:31 |
| Tuvix | If sending in the military to shore up the overburdoned healthsystem isn't a crisis, I don't know what is. | 01:31 |
| dTal | These are the people cloggiing up our hospitals. I don't have patience anymore. Fine the dickheads. Make them pay for their ignorance for a change. | 01:31 |
| sdfgsdfg | you will have the double dosed dickheads clogging it up | 01:32 |
| sdfgsdfg | as soon as you reach the australian vaccination rate | 01:32 |
| de-facto | vaccinations prevent 4 out of 5 hospitalizations | 01:34 |
| sdfgsdfg | how many doses are you talking about de-facto , the term vaccination became a complex umbrella term | 01:34 |
| sdfgsdfg | you can go up to 4 in somewhere like israel, and 3 in most now | 01:34 |
| dTal | If they think requiring a negative test - that you can easily fake! - is a hate crime, then their opinions don't count. | 01:35 |
| Tuvix | Even 2-doses of mRNA has a major impact on ICU and fatality counts, even if protection against symptomatic infection is much worse now (due to both varients and waning effectiveness) | 01:35 |
| sdfgsdfg | does it protect even 45% 3 months after you get your third shot ? can you answer this one for example | 01:35 |
| Tuvix | Once again, our crystal balls are in the shop. Probably for a while. | 01:36 |
| de-facto | its described in detail in https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/1046853/technical-briefing-34-14-january-2022.pdf | 01:37 |
| sdfgsdfg | thanks for the link de-facto that's an awesome resource | 01:38 |
| sdfgsdfg | looks like omicron really suppressed delta in uk | 01:38 |
| sdfgsdfg | wows | 01:38 |
| de-facto | "Results for hospitalisations are shown in Table 2. " | 01:39 |
| de-facto | "One dose of vaccine was associated with a 43% reduced risk of hospitalisation among symptomatic cases with the Omicron variant, 2 doses with a 55% reduction up to 24 weeks after the second dose and a 40% reduced risk 25 or more weeks after the second dose, and a third dose was associated with a 74% reduced risk of hospitalisation in the first 2 to 4 weeks after vaccination, dropping slightly to a 66% reduction by 10+ weeks after the booster dose." | 01:40 |
| de-facto | "When combined with vaccine effectiveness against symptomatic disease this was equivalent to vaccine effectiveness against hospitalisation of 58% after one dose, 64% 2 to 24 weeks after 2 doses, 44% 25+ weeks after 2 doses, and 92% dropping to 83% 10+ weeks after a booster dose. " | 01:40 |
| de-facto | "Combining the periods for the third dose, overall vaccine effectiveness 2+ weeks after the booster was 89% (95% confidence interval 86 to 91%)." | 01:40 |
| de-facto | on their page 24 | 01:40 |
| de-facto | .title https://www.gov.uk/government/publications/investigation-of-sars-cov-2-variants-technical-briefings <-- worth keeping an eye upon | 01:40 |
| Brainstorm | de-facto: From www.gov.uk: Investigation of SARS-CoV-2 variants: technical briefings - GOV.UK | 01:40 |
| Tuvix | Though presumably it's 10+ because we don't have significant data for more time-divisions beyond that (ergo 3 or more months out is still being studied as this virus continues to study us) | 01:41 |
| de-facto | .title https://www.nature.com/articles/d41591-022-00017-z <-- probably relevant in that context of vaccine efficacy against hospitalization | 01:44 |
| Brainstorm | de-facto: From www.nature.com: Ancestral SARS-CoV-2-specific T cells cross-recognize Omicron | 01:44 |
| sdfgsdfg | wish they had some comparison with natural immunity as well | 01:45 |
| Brainstorm | New from r/WorldNews: worldnews: Wealth of world's 10 richest men doubled in pandemic, Oxfam says → https://old.reddit.com/r/worldnews/comments/s6jqhd/wealth_of_worlds_10_richest_men_doubled_in/ | 01:51 |
| LjL | <sdfgsdfg> you can go up to 4 in somewhere like israel, and 3 in most now ← man, you've missed the 5th in Turkey?! | 02:00 |
| sdfgsdfg | lol, if this was a competition the indian man who got 10 shots in one day would win thid game :D | 02:01 |
| sdfgsdfg | anybody know if you train your adaptive immune system, T and B cells to recognize a certain pathogen, does that affect the recognition of other viruses / terminal illnesses ? | 02:12 |
| de-facto | .title https://www.worldometers.info/coronavirus/country/US <-- 800k infections *each single day* in the US | 03:13 |
| Brainstorm | de-facto: From www.worldometers.info: United States COVID - Coronavirus Statistics - Worldometer | 03:13 |
| de-facto | thats crazy | 03:13 |
| de-facto | probably in reality millions | 03:14 |
| Brainstorm | New from r/WorldNews: worldnews: Populist politics lost support globally during the pandemic, research finds → https://old.reddit.com/r/worldnews/comments/s6lm4y/populist_politics_lost_support_globally_during/ | 03:17 |
| Tuvix | de-facto: Daily death rates probably already have exceeded the worst rate we saw in Delta too, but the CDC chart won't update until tomorrow given the federal holiday today. | 03:39 |
| Tuvix | The caseload itself is astonishing, but notwithstanding the worst per-day fatality rate certainly going to be more than Delta, the total deaths from Omicron may well exceed it too given the supply of unvaccinated for it to get more rolls of the statistical dice with. | 03:40 |
| de-facto | quite scary, in Germany we may have a similar vaccination rate | 03:44 |
| Tuvix | JHU says you've about 9% ahead of the US, nationally anyway. I understand it varies that a lot by region, as it does here. | 03:45 |
| Tuvix | Oh, no, 11.5%, I read the offset from 10 the wrong way when I hovered | 03:45 |
| Tuvix | Wyoming state here still bringing up the rear with 48.0% fully vaccinated (2+ doses, or 1 J&J) | 03:46 |
| Tuvix | Still, overall death by population is now 259.14/100k for the US, and 139.12/100k for Germany, so those are hard numbers to argue with as an overall strategy comparison. | 03:48 |
| Tuvix | That's just crazy. In about 2 years that's 1 in 386 taken by this virus. | 03:49 |
| de-facto | https://ourworldindata.org/explorers/coronavirus-data-explorer?zoomToSelection=true&facet=none&pickerSort=asc&pickerMetric=location&Interval=7-day+rolling+average&Relative+to+Population=true&Color+by+test+positivity=false&country=USA~DEU&Metric=People+vaccinated+%28by+dose%29 | 03:49 |
| Tuvix | Well, partially is pretty worthless assuming that means 1x mRNA. | 03:50 |
| de-facto | well yeah but still better than naive immune system, especially if we are talking about fatal outcome | 03:50 |
| Tuvix | Lovely to see the US leading the way in another crappy metric, the one of "started but didn't finish the vacines." Unless a good part of that 12% are people waiting for their 2nd dose eligibility, but I'm pretty sure it's not given we have no effective requirements here to encourage that. | 03:50 |
| Tuvix | 35% reduction of hospitalisation perhaps, according to the 31-Dec UK Technical briefing. | 03:53 |
| de-facto | maybe when the next mutant after Omicron makes a big wave people may start to rethink that "pandemic is over" wishes and try to put more effort into working towards that by preventing infections | 03:53 |
| Tuvix | I'd have hoped that Delta would have done that because the change in both cases (during the summer here no less) and death was significant, but nope. | 03:54 |
| de-facto | maybe the next mutant is more severe? we will see | 03:54 |
| Tuvix | Given the *lowest* rate of death as compared to early July, which was pretty good at just under 0.5/100k/7-days, has been about 2.5/100k/7-days. | 03:55 |
| Tuvix | That is to say that after Delta stopped peaking, we "got down to" not (notably) less than five times the best pre-Delta rate. That's… disturbing. | 03:56 |
| de-facto | i think its a mistake to "let it burn through" that will claim many lives | 03:57 |
| Tuvix | Maybe Omicron's behavior means we can see a sharper decline of death rates once we stop having the enormous cases, but it may just continue to simmer in all the people it didn't infect during that first wave, or some months later begin re-infecting some and halt the steady decline in deaths we say after what was probably the alpha surge. | 03:57 |
| de-facto | i just dont get why we still have this strategy after so many variants proving the opposite, it does not work | 03:58 |
| Tuvix | I mean, that's basically what the US is doing. Rules to contain the spread are getting overturned by federal & state courts, or undone by governors at the head of state leaderships, and even where rules exist they're often not enforced well if at all. | 03:58 |
| de-facto | yeah and that is the reason death rates will rise | 03:59 |
| Tuvix | Just this week the new Virginia governor overturned the mask requirement for schools, since he ran partially on a platform of "parents know best for their children | 03:59 |
| de-facto | why would it be different compared to all the other variants? | 03:59 |
| de-facto | its all the same, just in a bit different shades of symptoms | 03:59 |
| Tuvix | Well, if it was more mild and it significantly ran out of the rate of those getting infected, but my prediction is that it won't since there are still I'm sure plenty it hasn't yet infected, or who got a low enough viral load that the immune system didn't really build up much protection. | 04:00 |
| de-facto | humans simply are not acting rational or according to observed data, rather they seem to act emotionally like children for some reason | 04:01 |
| Tuvix | And in any given individual it may be, on average, more mild, but that's certainly not an end result that's better than delta, not if your measuring stick is how many have died. | 04:01 |
| de-facto | wishing for something and ignoring every observation that is not compatible with it | 04:01 |
| Tuvix | I mean, that's what the US does after school gun shootings here. Nothing really ever changes, but there's a vocal group on social media that "sends prayers and wishes." It didn't help that problem, and doesn't seem to have helped here. | 04:02 |
| de-facto | infections are rising sharply, hospitalizations follow with a delay, deaths follow with even a bigger delay (depending on age loosing the fight for the life may take longer time) | 04:03 |
| Tuvix | Of course, who knows, maybe the vaccines *were* really the answer to prayer, and then be ignored by many of those that hoped we'd get such a great outcome. | 04:03 |
| de-facto | hence not increasing containment and preventing infections means killing people by those decisions | 04:04 |
| Tuvix | The delay and lack of immediate symptoms don't help the culture where you can get satisifcation on-demand with your electronics at home, and order most goods shipped to your door in 2 days (or less, in some areas that's even down to same-day delivery) | 04:04 |
| de-facto | there is a clear causal chain connecting infections with fatal outcomes known to everybody, hence every infection not prevented is risking that infection chain resulting in killing someone | 04:05 |
| Tuvix | I'm also convinced so much of the resistance to vaccines are a perceived lack of urgency. If COVID was no more lethal than it is now but gave people the bumps associated with smallpox, people would be lining up in droves for the vaccines. | 04:05 |
| de-facto | if only people could see the damage it does to their inner organs | 04:06 |
| de-facto | wrecking their lungs in fibrosis, destroying small vessels, damaging their brains etc | 04:07 |
| de-facto | may not look ugly on a photo but may mean significant damage to their health and life expectancy | 04:07 |
| de-facto | if diagnosis could also be done by x-rays of the lungs by seeing ground-glass opacity like features, the damage must be massive | 04:09 |
| de-facto | if not only biomarkers for neuro-injury rise but there are actual *physical* changes in brain volume visible on MRI again, thats not a minor issue then | 04:10 |
| de-facto | if many people do not recover after *months* with highly activated immune systems and/or other long lasting health problems severely limiting them in their daily life, that is a major issue that is not even seen at all in fatality stats | 04:12 |
| de-facto | it may lead to significantly lowering average life expectancy though as well as significantly lower productivity etc | 04:12 |
| de-facto | and that will happen to a constant fraction of those millions that get infected everyday, also by Omicron | 04:13 |
| Tuvix | Depending on the long-term impacts, children may see a lot of yet-unkown issues too, especially since some are still too young to be vaccinated, and many of the rest are less vaccinated than older age-groups. | 04:13 |
| de-facto | it may be a bit different fraction, depending on mutant (Omicron, Delta, etc) and depending on other factors such as age, sex, comorbs, vaccination etc, but still the point is that its a constant fraction determined by those conditions | 04:13 |
| de-facto | hence if infections double those with such health damage double | 04:14 |
| de-facto | that already can be seen by that daily new infections divided by daily hospitalizations 10 days ago (e.g. in UK) give *constant* factor | 04:15 |
| Brainstorm | New from r/Science: science: Support for populist politics ‘collapsed’ during the pandemic – global report → https://old.reddit.com/r/science/comments/s6ltfr/support_for_populist_politics_collapsed_during/ | 04:34 |
| LjL | holy crap, *one* FFP2 Aura has gone up to €9 on Amazon | 05:22 |
| LjL | no, €8.30, €9 is the FFP3, but still | 05:22 |
| Juerd | LjL: Which country are you in? | 05:32 |
| Juerd | LjL: https://www.praxisdienst.com/en/Hygiene/Protective+Wear/Surgical+Masks/3M+Aura+FFP2+Respirator+Face+Mask.html is the cheapest I could find. There's a list of countries they ship to at https://www.praxisdienst.com/en/shipping+and+delivery+conditions/?force_sid=45ip6h50arvv5on8gboam9dmjt | 05:34 |
| Juerd | Those are not just cheap, that price is almost prepandemic :) | 05:35 |
| LjL | Juerd, Italy | 05:42 |
| LjL | hmm shipping to italy is 6.83 | 05:43 |
| LjL | that's not too bad except i usually buy just like 5 of them | 05:43 |
| LjL | still slightly cheaper than the pack of 5 on amazon (which is €20) | 05:43 |
| LjL | (i use other, cheaper masks for day to day things, and reserve the Auras to more perilous situations) | 05:43 |
| Juerd | I use auras exclusively. I have about 10 in rotation and replace one a week on average. | 05:45 |
| Juerd | Most often because a strap breaks (I always bring a spare) | 05:46 |
| LjL | i find them quite burdensome to wear, tbh | 05:46 |
| LjL | yeah their straps are not up to par with the rest of the masks' quality | 05:46 |
| Juerd | The breathability is great, especially considering how well they seal. What's burdening you with these? | 05:47 |
| LjL | i also haven't convinced anyone in my family to ever wear Auras, so buying more than 5 or so of them could be a waste. right now i think i have 2 left | 05:47 |
| * Juerd has about 40 left. Couldn't resist when I had the chance to buy them cheaply. | 05:47 | |
| Juerd | At the current rate that'll last me until well after next summer. | 05:48 |
| LjL | Juerd, well i guess i don't want to try out the breathability of *less* breathable masks that seal well. i do realize that a good seal is important, but when i got my vaccine which took a couple of hours of continuously wearing an Aura, at some point during my 15 minute wait it started literally dripping water onto my pants. quite unpleasant and somewhat embarrassing. | 05:48 |
| Juerd | Was that outside? | 05:48 |
| LjL | other times when i wore them and spent some time talking to people, my eyes got extremely irritated, which lasted a few days. it happened more than once, at first i didn't think it could be the mask, but it definitely was | 05:49 |
| Juerd | Because well sealing masks are basically impossible to wear in the cold because of condensation which can't go anywhere. | 05:49 |
| LjL | no it was indoors at the vaccine center | 05:49 |
| LjL | well the vaccine center was... cool this winter, but i got the vaccine where i remember that happening in July | 05:49 |
| Juerd | That's weird. I typically wear them for 6 or so hours, but have done 12. | 05:49 |
| LjL | the climate here tends to be quite humid | 05:50 |
| Juerd | As for eye irritation, that's weird too, because they should seal practically perfectly around the nose | 05:50 |
| Juerd | I see | 05:50 |
| LjL | i don't think they seal all that perfectly because my glasses (clear glasses, i don't wear lenses) still got fogged | 05:50 |
| Juerd | Eye irritation is one of the reasons I wear auras, because with "fish"/"boat" style masks and "surgical" masks I keep blowing air into my eyes. | 05:50 |
| Juerd | LjL: Ah, with glasses you may be wearing the glasses above the mask, instead of on top of it, in which case you can't get a good seal as easily. | 05:51 |
| LjL | what about the KF94 style? | 05:51 |
| Juerd | Auras go high up the nose usually | 05:51 |
| LjL | maybe i'm also just allergic to whatever the sealing foam is | 05:52 |
| Juerd | KF94 is a filtration and leakage standard, not a shape. The aura-ish shape of most korean masks is what I referred to as fish/boat (aliexpress calls them fish, Aaron Collins calls them boat) | 05:52 |
| LjL | i definitely used to have allergies | 05:52 |
| LjL | i know that, but they tend to have that shape | 05:52 |
| LjL | i thought you were referring to the "KN95-typical" shape | 05:52 |
| LjL | () | 05:52 |
| LjL | then i find their Aura-ish shape at least better than most of the () masks | 05:53 |
| Juerd | KN95 is also a filtration and leakage standard, but the typical bifold style I usually call coffee filter because they | 05:53 |
| Juerd | look like those | 05:53 |
| LjL | i have no idea what a coffee filter looks like to you, we use Moka pots :P | 05:54 |
| LjL | but yeah, bifold | 05:54 |
| Juerd | https://upload.wikimedia.org/wikipedia/commons/1/12/Koffiefilter_RA.jpg | 05:55 |
| LjL | definitely not familiar with those | 05:56 |
| Juerd | https://upload.wikimedia.org/wikipedia/commons/a/ae/Kaffeefilter.jpg is how they're used | 05:56 |
| Juerd | The holder obviously has holes in the bottom | 05:56 |
| Juerd | Anyway, the typical bifold style resembles these things quite a lot | 05:57 |
| Juerd | Anyway, most vertical bifolds don't work for me, surgical doesn't work for me, fish/boat doesn't work for me. With all of these I end up blowing air in my eyes. | 06:00 |
| Juerd | The only masks I've found to work for my face are the 3m aura and a vertical bifold ffp3 mask from before the pandemic started, that I can now not find for sale anywhere. | 06:00 |
| Brainstorm | New from r/Science: science: Large-Scale Study of Antibody Titer Decay following BNT162b2 mRNA Vaccine or SARS-CoV-2 Infection → https://old.reddit.com/r/science/comments/s6o64q/largescale_study_of_antibody_titer_decay/ | 06:08 |
| mrdata | https://twitter.com/unapologeticAnk/status/1478462093783302147 | 06:24 |
| mrdata | ^ if true, this doesnt sound like covid | 06:25 |
| mrdata | oh but this was tweeted on jan.4 | 06:25 |
| mrdata | ok, followups explain, the lock down is due to covid but hanta virus is endemic | 06:27 |
| Brainstorm | New from COVID on Twitter: Eric Topol (@EricTopol): Last point, which I cannot emphasize enough:3rd shot protection vs Omicron hospitalizations, severe disease, death is remarkably high, about as well preserved as 2 shots vs ancestral strain, and a very different look compared with VE vs [... want %more?] → https://twitter.com/EricTopol/status/1483302665899577345 | 06:27 |
| de-facto | Hantavirus? | 06:33 |
| de-facto | ah you wrote it already | 06:33 |
| de-facto | .title https://www.globaltimes.cn/page/202112/1242782.shtml | 06:34 |
| Brainstorm | de-facto: From www.globaltimes.cn: Xi 'an reports hemorrhagic fever cases, but no need to panic as medical experts urge quick vaccinations - Global Times | 06:34 |
| Brainstorm | New from r/WorldNews: worldnews: Over 70,000 attend German protests against COVID measures; In what's becoming a regular event on Monday evenings, protesters took to the streets of Berlin, Cologne, Cottbus and Rostock, as well as several other locations across Germany → https://old.reddit.com/r/worldnews/comments/s6pkrl/over_70000_attend_german_protests_against_covid/ | 06:37 |
| Brainstorm | New from r/WorldNews: worldnews: ‘People are spooked’: Australia’s January consumer confidence sinks to three-decade low over Omicron → https://old.reddit.com/r/worldnews/comments/s6pwdy/people_are_spooked_australias_january_consumer/ | 06:56 |
| de-facto | .title https://www.mdpi.com/2076-393X/10/1/64 | 07:03 |
| Brainstorm | de-facto, the URL could not be loaded | 07:03 |
| * de-facto slaps Brainstorm | 07:06 | |
| Brainstorm | de-facto: Do as you wish! | 07:06 |
| de-facto | "Large-Scale Study of Antibody Titer Decay following BNT162b2 mRNA Vaccine or SARS-CoV-2 Infection" | 07:06 |
| de-facto | quite interesting, they compare vaccination with infection antibody level decay | 07:07 |
| de-facto | but i dont like their datapoint density: for vaccination it got weights on begin and end of the timerange while for infection it got weight in the middle of the timerange | 07:07 |
| de-facto | hence that would also influence the fit function if point density would not be conterbalanced by weighting | 07:08 |
| de-facto | (i guess this is due to waves in both, vaccination and infection incidence) | 07:09 |
| de-facto | vaccination: point blobs and begin and end https://www.mdpi.com/vaccines/vaccines-10-00064/article_deploy/html/images/vaccines-10-00064-g003-550.jpg | 07:10 |
| de-facto | infection point blob at the center https://www.mdpi.com/vaccines/vaccines-10-00064/article_deploy/html/images/vaccines-10-00064-g004-550.jpg | 07:10 |
| Brainstorm | New from r/WorldNews: worldnews: China blames mail from Canada for Omicron case in Beijing → https://old.reddit.com/r/worldnews/comments/s6qmul/china_blames_mail_from_canada_for_omicron_case_in/ | 07:35 |
| Brainstorm | New from r/WorldNews: worldnews: The poor die from COVID while the rich get richer, Oxfam warns → https://old.reddit.com/r/worldnews/comments/s6rk0r/the_poor_die_from_covid_while_the_rich_get_richer/ | 08:31 |
| Brainstorm | New from r/WorldNews: worldnews: Shanghai mall locks in shoppers for 55 hours for COVID testing → https://old.reddit.com/r/worldnews/comments/s6ruo6/shanghai_mall_locks_in_shoppers_for_55_hours_for/ | 08:50 |
| Brainstorm | New from r/Coronavirus: Daily Discussion Thread | January 18, 2022: Please refer to our Wiki for more information on COVID-19 and our sub. You can find answers to frequently asked questions in our FAQ , where there is valuable information such as our: → https://old.reddit.com/r/Coronavirus/comments/s6s9zk/daily_discussion_thread_january_18_2022/ | 09:09 |
| xx | if the vaccines become mandatory, do you think they'll ever stop being mandatory, e.g. in 10 years time? | 09:34 |
| xx | what they should do is assign every person an unchanging qr code that links to the vaccination status, so that I could just tattoo it on the back of my hand | 09:35 |
| sdfgsdfg | I think they will keep jabbing people for a straight decade | 09:47 |
| sdfgsdfg | but it's already going wrong in israel | 09:48 |
| sdfgsdfg | it's not going wrong I mean people are losing trust | 09:48 |
| sdfgsdfg | or media is releasing hesitant articles about the necessity of 483t69358th shot | 09:48 |
| sdfgsdfg | and it's very vaccine hesitant of them, they should have more faith in their new dose and continue as the world's trial hamsters nation | 09:49 |
| dTal | Your tone is beginning to worry me, sdfgsdfg. | 10:08 |
| sdfgsdfg | I'm just trying to adapt to the times | 10:08 |
| sdfgsdfg | in a sarcastic way | 10:09 |
| dTal | I would encourage you to make an attempt to engage with the actual issues that people are trying to solve, instead of retreating into anger. | 10:10 |
| dTal | There's plenty to be upset about that has more basis in reality than some abstract "they" who really likes vaccinating people unneccesarily. | 10:12 |
| sdfgsdfg | of course. I realized this is unnecessary + 1, Ill just contribute instead. I hope it gets better though | 10:12 |
| sdfgsdfg | some hope would be good, endemic doesn't look very bright with vax subscriptions and efficiency micromanaging while people are still dying | 10:12 |
| dTal | For example, I'm upset that the UK government require negative lateral flows to get into venues on Saturday nights, but allow people to self report them, which results in piles of unused tests in the street as people rip them open just to scan the QR codes. | 10:13 |
| dTal | I'm not too worried about the long term, virus-wise. The danger of covid comes from the population being immune naive. It's still pretty immune naive, despite our best efforts with vaccination. It's a problem that will solve itself in time. | 10:14 |
| dTal | It would be better if we could solve it faster, with updated vaccinations. | 10:15 |
| dTal | But I don't think we need to worry about some dystopian future where we're getting the same old Pfizer jab for the 100th time in 2050 | 10:16 |
| Dredd | dTal: we'll all be looking back on the vaccine wars of 2028 😉 | 10:25 |
| Dredd | World War V.... | 10:25 |
| Brainstorm | New from r/WorldNews: worldnews: 2,000 hamsters to be culled in Hong Kong over fears of animal-to-human Covid-19 link → https://old.reddit.com/r/worldnews/comments/s6tb6t/2000_hamsters_to_be_culled_in_hong_kong_over/ | 10:26 |
| xx | I'm more thinking about making it more convenient for everyone, by having an unchanging qr code tattooed on back of hand so that it is easy to read on public cameras and track the vaccinated and unvaccinated | 10:34 |
| xx | so that one day you can walk out of your home, a camera will read the code and then the nearest shot would alert you that your vaccine is expired | 10:34 |
| xx | *shop | 10:35 |
| xx | I don't own a cell phone, and dislike taking a paper with me everywhere | 10:35 |
| xx | so always having it on my body where it is clearly visible to everyone around me would be of great help | 10:36 |
| Brainstorm | New from r/WorldNews: worldnews: Covid hamster outbreak: Hong Kong to cull ALL rodents as 11 found infected with virus → https://old.reddit.com/r/worldnews/comments/s6te0h/covid_hamster_outbreak_hong_kong_to_cull_all/ | 10:36 |
| xx | but obviously it doesn't currently work, because the qr code is different after every shot instead of being permanent | 10:36 |
| xx | I wouldn't want to be doing tattoo removal all the time | 10:36 |
| Brainstorm | New from StatNews: U.S. would seek global approach to updating Covid-19 vaccines, official says: If the Food and Drug Administration decides to update Covid-19 vaccines to take better aim at Omicron or other variants, it is unlikely to go it alone. → https://www.statnews.com/2022/01/18/u-s-would-seek-global-approach-to-updating-covid-19-vaccines-official-says/ | 10:46 |
| Brainstorm | New from StatNews: Opinion: Is it time for big biopharma companies to rethink the use of federal funding for R&D?: My take-home lessons from having negotiated Covid-related contracts with the federal government is that government may be a better contracting partner than biopharma [... want %more?] → https://www.statnews.com/2022/01/18/biopharma-companies-federal-funding-research-development/ | 10:56 |
| Brainstorm | New from r/WorldNews: worldnews: Hong Kong to kill all hamsters in pet shops after the animal tests positive of Covid-19 in world's first case → https://old.reddit.com/r/worldnews/comments/s6txvm/hong_kong_to_kill_all_hamsters_in_pet_shops_after/ | 11:16 |
| Brainstorm | New from ScienceNews: Scientists vacuumed animal DNA out of thin air for the first time: The ability to sniff out animals’ airborne genetic material has been on researchers’ wish list for over a decade. → https://www.sciencenews.org/article/animal-dna-air-scientist-vacuum-first-time-zoo | 12:05 |
| Brainstorm | New from r/WorldNews: worldnews: France passes law to exclude unvaccinated people from public places → https://old.reddit.com/r/worldnews/comments/s6vgrp/france_passes_law_to_exclude_unvaccinated_people/ | 12:53 |
| Brainstorm | New from BMJ: (news): Covid-19: Government ignores scientists’ advice to tighten restrictions to combat omicron → http://www.bmj.com/content/376/bmj.o135.short | 13:03 |
| Brainstorm | New from r/WorldNews: worldnews: Doctors say China's claim 1st Omicron case came from Canada isn't scientifically possible → https://old.reddit.com/r/worldnews/comments/s6vuly/doctors_say_chinas_claim_1st_omicron_case_came/ | 13:13 |
| Brainstorm | New from Politico: French education minister’s Ibiza trip adds fuel to teachers’ anger: Jean-Michel Blanquer was in Ibiza when he laid out the pandemic plan that got him the biggest teacher's strike in years. → https://www.politico.eu/article/french-education-minister-jean-michel-blanquer-ibiza-trip-adds-fuel-to-teachers-anger/ | 13:32 |
| Brainstorm | New from r/Science: science: Faith in god or ‘a higher power’ was greatly weakened by the pandemic: In a cross-sectional survey done in Germany, 15 % of participants said they had lost faith in god due to COVID-19 during the first wave. Fraction of participants reporting loss [... want %more?] → https://old.reddit.com/r/science/comments/s6wh3v/faith_in_god_or_a_higher_power_was_greatly/ | 14:00 |
| Brainstorm | New from Contagion Live: us: High False-Positive Rate with Rapid Antigen Test for SARS-CoV-2 Linked to Single Batch from Manufacturer → https://www.contagionlive.com/view/high-false-positive-rate-with-rapid-antigen-test-for-sars-cov-2-linked-to-single-batch-from-manufacturer | 14:29 |
| Brainstorm | New from r/Science: science: Fourth Pfizer Dose Is Insufficient to Ward Off Omicron, Israeli Trial Suggests → https://old.reddit.com/r/science/comments/s6xwc6/fourth_pfizer_dose_is_insufficient_to_ward_off/ | 15:39 |
| Brainstorm | New from r/COVID19: COVID19: Indirect effects of the covid-19 pandemic on childhood infection in England: population based observational study → https://www.reddit.com/r/COVID19/comments/s6yjqj/indirect_effects_of_the_covid19_pandemic_on/ | 15:49 |
| Brainstorm | New from EMA: Human medicine assessment reports: (news): Human medicines European public assessment report (EPAR): Menveo, meningococcal group A, C, W-135 and Y conjugate vaccine, Immunization;Meningitis, Meningococcal, Date of authorisation: 15/03/2010, Date of refusal: 17/12/2009, Revision: 31, Status: Authorised → https://www.ema.europa.eu/en/medicines/human/EPAR/menveo | 15:59 |
| Brainstorm | New from BBC Health: Scotland to lift most remaining Covid restrictions: Nightclubs will reopen and large indoor events can resume from 24 January, Nicola Sturgeon confirms. → https://www.bbc.co.uk/news/uk-scotland-60042339 | 16:39 |
| lastshell | https://nypost.com/2022/01/18/fourth-covid-vaccine-still-doesnt-stop-omicron-israeli-study/amp/ | 16:43 |
| lastshell | 4th jab doesn't stop omicron, I guess that was clear since 2 or 3 jabs didn't stop it they need to target the variant | 16:44 |
| Brainstorm | New from EMA: Human medicine assessment reports: (news): Human medicines European public assessment report (EPAR): Vaxzevria (previously COVID-19 Vaccine AstraZeneca), COVID-19 Vaccine (ChAdOx1-S [recombinant]), COVID-19 virus infection, Date of authorisation: 29/01/2021, [... want %more?] → https://www.ema.europa.eu/en/medicines/human/EPAR/vaxzevria-previously-covid-19-vaccine-astrazeneca | 16:49 |
| JoeLlama | freep freep | 17:17 |
| bleb | <bleb> how do you interpret this https://i.ibb.co/dbcmgTG/covid.png | 17:33 |
| bleb | update: this was positive if anyone cares | 17:33 |
| de-facto | so was it a regular positive or "out of CT range, but positive"? | 17:34 |
| bleb | regular positive | 17:34 |
| Tuvix | Very confusing presentation, but I guess the reading of 'positive' in big bold letters being positive was the right approach if one had to guess. | 17:35 |
| lastshell | bleb I hope is omicron | 17:37 |
| Brainstorm | New from LitCovid: (news): [CERCAR to COVID-19: A structured communication model for the follow-up of cases and contacts in Primary Care]. → https://www.ncbi.nlm.nih.gov/research/coronavirus/publication/35037912 | 17:38 |
| bleb | I got the result yesterday from a wednesday test | 17:43 |
| bleb | it was a mild cold | 17:43 |
| bleb | apparently I'm already done with the 5 day isolation period lol | 17:44 |
| Tuvix | Realistically about 30% of people are still contagious 5-days after a positive test, and 5% (some hints it might even be as high as 10%) after 10-days. | 17:47 |
| Tuvix | If you're referring to the CDC guidance, that's also predicated on wearing a quality (N95 or similar) mask anytime you're with anyone, in part to balance out the fact that there's 3 in 10 odds you're still able to spread it after day-5. The advice doesn't really mention the risk enough here, at least to me. | 17:48 |
| Brainstorm | New from LitCovid: (news): A fatal case of COVID-19 breakthrough infection due to the delta variant. → https://www.ncbi.nlm.nih.gov/research/coronavirus/publication/35035958 | 17:48 |
| de-facto | bleb, drink Green Tea, it helps inactivating free floating virions and also is very healthy in general (in normal amounts) | 17:57 |
| bleb | I might have some oolong | 17:59 |
| lastshell | bleb I had omicron as well, just relax sleep drink a lot of water | 18:01 |
| lastshell | follow the advices from some folks here there are very smart | 18:02 |
| Brainstorm | New from EuroNews: What is the EU's Stability and Growth Pact and why is it important?: The bloc's fiscal rulebook has been suspended until next year to stave off any unwanted economic consequences of the pandemic. #BrusselsBureau → https://www.euronews.com/2022/01/18/what-is-the-eu-s-stability-and-growth-pact-and-why-is-it-important | 18:18 |
| Brainstorm | New from NPR: Fauci says COVID-19 won't go away like smallpox, but will more likely become endemic: The White House's top medical advisor says the virus won't go away entirely. Instead, it is more likely to hit a level where it "doesn't disrupt our [... want %more?] → https://www.npr.org/sections/coronavirus-live-updates/2022/01/18/1073802431/fauci-says-covid-19-wont-go-away-like-smallpox | 18:27 |
| Brainstorm | New from BMJ: Covid-19: Reassess effects of mandatory vaccination on staffing, urge unions: Healthcare unions are urging the government to carry out an updated impact assessment on how its policy of mandatory covid-19 vaccination for healthcare workers in England will affect staffing... → http://www.bmj.com/content/376/bmj.o139.short | 18:57 |
| Arsanerit | My sister works in a hospital and now her partner has tested positive on a PCR test. | 19:05 |
| peetaur | did she test too? | 19:08 |
| peetaur | and next question will be, and what does she plan to do about it? you'd think she would know and not need any discussion here :D | 19:09 |
| de-facto | she should wear FFP3 at home and test regularly | 19:19 |
| Brainstorm | New from r/WorldNews: worldnews: Spain to move from treating COVID-19 as a pandemic to an endemic → https://old.reddit.com/r/worldnews/comments/s73lv3/spain_to_move_from_treating_covid19_as_a_pandemic/ | 19:25 |
| LjL | "Spain has suggested it wants to change **the way it monitors the pandemic** in order to return to normal life by no longer seeing it as a pandemic, but as an endemic, an ordinary cold virus." | 19:33 |
| LjL | i keep hearing suggestions from more and more places to basically stop counting deaths as separate from other respiratory disease deaths | 19:33 |
| LjL | which goes together, i guess, with many countries seemingly adopting or being about to adopt the CDC's 5-days-no-test guideline | 19:34 |
| LjL | "I think this is more about politics than public health. After each wave, they make a new suggestion. Earlier it was the outdoor face masking, now it is to stop counting and stop testing," Lazarus told Euronews. | 19:34 |
| LjL | "stop counting and stop testing", also sounds like the test-bashing there has been here lately | 19:34 |
| LjL | it also does talk about "resistance from both Germany and France, where vaccine uptake remains lower than in Spain, where more than 90% of the eligible population is now fully vaccinated and 85% of those over 60 have had their booster dose." | 19:36 |
| LjL | and really even here, while vaccines are doing better than France or Germany, we're not close to 85% of over 60 having gotten their booster | 19:37 |
| LjL | it's 67.02% between 60 and 70, 74.50% between 70 and 80, and 78.69% for 80+ | 19:37 |
| Tuvix | Scaling back testing is possibly dangerous for another reason: that will have the effect of longer lead-time to identify a new emerging varient that could very well be more deadly or otherwise cause society more trouble than the prior prevailing varients. | 19:37 |
| Tuvix | Hmm, so I used my PO box for the US free 4 at-home COVID tests (site went live today) and it clearly said using an address or PO box in the entry field (PO box is heated, my street mailbox is not.) | 19:39 |
| Tuvix | However, the confirmation page then says, "USPS will only send one set of 4 free at-home COVID-19 tests to valid residential addresses." -- so will I get them? The PO box is not a "residential" address :\ | 19:39 |
| LjL | Tuvix, i think that's more a matter of how much sequencing there is... even with a lot of testing, the sequencing in many countries (like mine) is extremely limited. you could scale back testing *a lot* while still managing to sequence more cases. not saying it's a good idea but it would be possible | 19:39 |
| LjL | then there is also the chance of being alerted of a new variant by seeing a dropout in a PCR test, but apparently only the UK, South Africa, Denmark and a few select countries are competent enough to do that ;( | 19:40 |
| LjL | Tuvix, i don't know, are you concerned about the government knowing where you live? i suspect they already do :P | 19:41 |
| Tuvix | It's more about not letting the tests sit in the mailbox where it's winter and cold. No idea if that matters, but I use the box for all kinds of deliveries like that. | 19:42 |
| Tuvix | But the point is that if they aren't willing to ship to them, the form shouldn't have specifically told me that it wanted an address or PO box. | 19:42 |
| LjL | oh PO box is "heated", i originally read PO box is "needed" | 19:43 |
| Tuvix | Just got an automated USPS confirmation, so we'll see if it eventually ships in the next couple of weeks or gets rejected. | 19:44 |
| Tuvix | Hopefully enough of this is automated that no one bothers to cancel it. | 19:44 |
| Tuvix | I can get free testing locally too at pharmacies and other locations around the city, but these would still be convenient. | 19:45 |
| LjL | Tuvix, your request will be scrapped but you will be automatically considered positive and required to quarantine | 19:45 |
| Tuvix | I mean, the lack of reporting of these is an issue too, but unless a business or locality has specific requirements, it doesn't matter anyway for me. Starting tomorrow a handful of cities 100km or so away from me are requiring vaccination proof or a negative test within 72 hours to enter bars or in-person dining. No idea how that'll work in practice since we don't have anything resembling the QR codes or | 19:47 |
| Tuvix | green-pass parts of the EU are using. | 19:48 |
| Brainstorm | New from CDC (old): Coronavirus [CoV]: COVID-19 Travel Recommendations by Country → https://tools.cdc.gov/api/embed/downloader/download.asp | 20:14 |
| de-facto | for RAT the corrent temperature of the lateral flow thingy is very important | 20:14 |
| de-facto | because it influences antibody binding | 20:15 |
| de-facto | so if people order it via mail they would have to make sure to bring the test to correct temp prior to using it | 20:15 |
| Tuvix | That may apply to people who travel and keep the tests say in their car (or trunk, where it won't be warmed even if on a decently long drive.) Then use them say just before an event they want to have a pre-gathering test for. | 20:17 |
| de-facto | also taking the sample correctly is quite important, it may also be that for Omicron a throat swab would have a higher probability than a nose swab for delivering a correct result | 20:17 |
| Tuvix | Yea, I'd been following some of that nose/throat swap, although the "official" guidance here is to follow the test manufacturer. I think the jury is still out a bit as to how much if a difference there is. | 20:18 |
| de-facto | Tuvix, there are those "instant coffee" cans that mix CaO with H2O to generate heat from an exothermal reaction to heat the coffee, so heh maybe something similar could be done to create "instant rapid antigen tests"!? | 20:19 |
| Tuvix | I can see the marketing already: COVID-test: just add-water! /s | 20:20 |
| de-facto | problem is they would have to stay within a tight temperature range that is stabilized for the time of their lateral flow, e.g. for those 15 minutes or such | 20:21 |
| de-facto | not too cold not too warm | 20:21 |
| de-facto | iirc in AUstria they were doing the tests outdoors and they had some little "thermo boxes" that pre-heated the test to the target temp range and then stabilized the temp for the time of their lateral flow taking place | 20:23 |
| de-facto | electrically heated, maybe via light bulb or such | 20:23 |
| Brainstorm | New from r/COVID19: COVID19: The US government has launched an official website that will offer free COVID-19 tests to US homes. Starting next Wed, Jan 19th, every home in the U.S. can order 4 free at-home COVID-19 tests. The tests will be completely free—there are no [... want %more?] → https://www.reddit.com/r/COVID19/comments/s75jlo/the_us_government_has_launched_an_official/ | 20:34 |
| Brainstorm | New from r/WorldNews: worldnews: Priest and two soldiers among five arrested for trading fake Covid passports in Poland → https://old.reddit.com/r/worldnews/comments/s75kcy/priest_and_two_soldiers_among_five_arrested_for/ | 20:44 |
| Brainstorm | New from CIDRAP: COVID-19 Scan for Jan 18, 2022: Third vaccine dose and Omicron Race and monoclonal antibodies → https://www.cidrap.umn.edu/news-perspective/2022/01/covid-19-scan-jan-18-2022 | 21:13 |
| Brainstorm | New from WebMD: Feds' Website for Free At-Home COVID Tests Launches Day Early: Today, the Biden administration launched a website that allows users to order free COVID-19 rapid tests that will be shipped directly to their homes. → https://www.webmd.com/lung/news/20220118/website-free-covid-tests | 21:23 |
| LjL | Tuvix, it says "There’s a limit of four tests per residential mailing address." so that might be why PO box won't be liked | 21:31 |
| Tuvix | Right, but they didn't tell me that until AFTER I'd entered my info, in the field that specifically said "address or PO box" | 21:32 |
| Tuvix | Bit crappy to explain the rules after you've filled out a form by following the form's own directions. | 21:32 |
| Tuvix | "Checkmate." "No, I'm sory but I win because you failed to pat your head while you made the winning move. Better luck next time!" | 21:33 |
| Brainstorm | New from BBC Health: Hong Kong seizes hamsters from pet store for mass cull: A Delta outbreak in "zero Covid" Hong Kong will result in the euthanasia of 2,000 small mammals. → https://www.bbc.co.uk/news/world-asia-china-60038551 | 22:12 |
| Brainstorm | New from StatNews: Why big data didn’t deliver on its big promises to combat Covid-19: When the pandemic hit, tech companies pledged to let public health researchers mine their data for clues. Two years in, it’s clear that big data isn’t the panacea they’d hoped… → https://www.statnews.com/2022/01/18/big-data-covid-public-health/ | 22:22 |
| Brainstorm | New from CIDRAP: US government makes free COVID-19 tests available: Stephanie Soucheray | News Reporter | CIDRAP News Jan 18, 2022 Though cases appear to be plateauing in some Eastern cities, hospitalizations are still high across the country. → https://www.cidrap.umn.edu/news-perspective/2022/01/us-government-makes-free-covid-19-tests-available | 22:31 |
| Brainstorm | New from CIDRAP: Asia, parts of Europe tighten COVID-19 measures due to Omicron: Lisa Schnirring | News Editor | CIDRAP News Jan 18, 2022 Though early-hit nations are on the downslope of their Omicron surges, others are battling rising cases. → https://www.cidrap.umn.edu/news-perspective/2022/01/asia-parts-europe-tighten-covid-19-measures-due-omicron | 23:19 |
| Brainstorm | New from CIDRAP: Report outlines 8 steps for current, future pandemics: Mary Van Beusekom | News Writer | CIDRAP News Jan 18, 2022 Steps include launching a US international pandemic preparedness project and appointing a global health security envoy. → https://www.cidrap.umn.edu/news-perspective/2022/01/report-outlines-8-steps-current-future-pandemics | 23:38 |
| de-facto | after incidence in South Africa with Omicron peaked (and went down again) we NOW see fatalities rising https://www.worldometers.info/coronavirus/country/south-africa/ | 23:45 |
| de-facto | the peak of their Omicron wave was 4 weeks ago | 23:46 |
| de-facto | and the peak of their deaths is not even reached yet, its still rising | 23:46 |
| nahan | CDC or WH had been saying some/most of the US ramp up was Delta ? | 23:47 |
| de-facto | its a bit weird that the fatalities due to the Omicron peak come in so late now | 23:49 |
| de-facto | as opposed to their other waves (e.g. Delta) | 23:49 |
| de-facto | .title https://twitter.com/rid1tweets/status/1481889683969822721 | 23:51 |
| Brainstorm | de-facto: From twitter.com: Ridhwaan Suliman (@rid1tweets): "While #COVID19 case numbers, test positivity rates, and hospitalisations continue their decline across South Africa during this wave driven by #OmicronVariant, [...] | 23:51 |
| Tuvix | nahan: A big part of that in the US is that back in Nov/Dec, we never really recovered from Delta, so we had lots of death already, in fact we had about 5 times the death "after" the Delta surge came down compared to July, pre-Delta. | 23:51 |
| de-facto | hopefully its something related to the reporting system and not something that originates in Omicron properties | 23:52 |
| Tuvix | nahan: You can see the trend of death before Omicron hit was a fairly flat line (some bumps, but it was generally at about 2.25 - 2.5 per 100k deaths every 7 days) here, and compare that to the pre-Delta rise with the low back in early july that was *under* 0.5/100k 7-day average: https://covid.cdc.gov/covid-data-tracker/#trends_dailycases_7daydeathsper100k | 23:52 |
| de-facto | maybe it also could be something like Omicron wave peaking in the young and only later diffusing into the older vulnerable groups where it kills people | 23:53 |
| LjL | de-facto, well i guess if it were people just kinda dropping dead after supposedly recovering from Omicron, they may not necessarily even show up as COVID deaths. do we have excess deaths for South Africa? (even if we do i assume they are far from realtime) | 23:53 |
| nahan | so many variables to control for | 23:53 |
| Tuvix | The fact that the US never really recovered from Delta means that there was lots of death around already, and until Omicron came into those areas, they weren't going to see the sharp rise that Omicron has brought simply due to case volume and the number of unvaccinated who continue to fare far worse than those vaccinated. | 23:53 |
| Tuvix | Some areas are only just now starting to see Omicron displace Delta, so they're just on the very early parts of the upswing for fatal outcomes. | 23:54 |
| Tuvix | Oklahoma for instance is in a pretty bad spot. In earlier surges they saw hospitalizations ahead of the country avearge, but this time the trend is a lag for OK state; they're reporting some urban hospitals at ICU-capacity now, and it would seem the stress on hospitals is only going to get worse. That's a bad combination. | 23:56 |
| de-facto | .title https://www.samrc.ac.za/reports/report-weekly-deaths-south-africa | 23:56 |
| Brainstorm | de-facto, the URL could not be loaded | 23:56 |
| de-facto | "Report on Weekly Deaths in South Africa | 23:56 |
| de-facto | " | 23:56 |
| Tuvix | Ok, plus OK has a fairly low vaccination rate in national comparison, which won't help them either. | 23:56 |
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