libera/##covid-19/ Wednesday, 2022-02-23

BrainstormNew from WebMD: Pediatric ER Visits Rise for Firearms Injuries, Drug Poisonings During Pandemic: Visits to pediatric emergency rooms  for firearm injuries and drug poisonings went up during the pandemic. Overall, pediatric emergency room visits were down. → https://www.webmd.com/lung/news/20220222/pediatric-er-visits-rise-for-firearms-injuries-drug-poisonings-during-pandemic00:03
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): "Although boosting with a 3rd vaccine dose ...increased antibody levels 10- to 100-fold, whereas a 4th exposure in individuals with higher pre-boost antibodies resulted in less robust boosting (~5- to 10-fold)."biorxiv.org/content/10.110… @EJohnWherry @WherryLab [... want %more?] → https://twitter.com/EricTopol/status/149625958717522739200:12
LjL"A major factor influencing the magnitude of the boost was pre-3rd vaccine dose antibody concentrations, which were inversely correlated with the fold-change of antibody boosting. These observations suggest that pre-existing high titers of antibody may compete with memory B cells for antigen and limit the extent of antibody boosting."00:19
LjL(abstract) "Notably, antibody decay slowed significantly between 6- and 9-months post-primary vaccination, essentially stabilizing at the time of the 3rd dose."00:20
LjLwouldn't this suggest it'd be best to actually wait six months before a 3rd dose? (at least if Omicron hadn't been looming, i get why we got it earlier)00:20
TuvixIf the goal is to introduce B-cell (long-term cells able to produce *new* antibodies later during infection) that would seem reasonable indeed.00:21
TuvixI haven't done a ton of reading here, but my understanding is that as early as 3 or 4 months (excluding heavily immunocompromised that may need a 3rd dose earlier just to approach a 2-dose level for others) is still beneficial. There's probably some curve of decreasing value the closer you get them.00:22
TuvixHere again, I suspect antibodies are only a convenient way to measure the impact; we can't really tell how active the memory cells are, but we can easily measure antibodies before/after.00:23
TuvixThe end goal is immune response, and with infection that means antibody production, not just having some ready-to-go antibodies in the bloodstream.00:24
LjLi think the antibodies themselves may be important, why would the vaccine efficacy wane so quickly otherwise? B-cells are still perfectly capable of producing antibodies, just apparently, not quickly enough to avert things00:24
LjLif you have circulating antibodies you can react immediately00:25
TuvixThose cells often are pretty bad at their job after the first exposure (or perhaps even first 2, if you consider the 2-dose mRNA as separate shots; I think of them more as both required to "prime" the immune system.)00:25
TuvixThe B-cell memory from initial vaccination.00:26
TuvixI probably can't lay eyes on it quickly, but there was an article talking specifically about the interaction between T- & B- cells that was a good read some months ago.00:26
TuvixIt described the initial round of vaccination (2-dose mRNA) as yes, providing antibodies, but the B-cells (they referred to the lymph-node B-cells specifically here) were not all that great at producing effective antibodies. Good enough for earlier VoC's, but less so with Delta (this was a pre-Omicron article.)00:27
LjLwould this be something specific to mRNA vaccines as a technology, or to the kind of antigen presented, or general, or what?00:28
TuvixThis was before boosters were recommneded for people as well, but the article went on to note that in traditional 3-dose vaccines spaced at roughly 0, 1, & 6 months apart, the 3rd dose was crucial for that long-term cell memory to produce *good* antibodies.00:28
TuvixI don't think it really has anything to do with mRNA given the connection to other vaccines typically given in one's youth that require similar dosing.00:28
LjLwell, but then it seems even the 3rd shot wanes about as quickly as the second, iirc00:28
LjL(for Omicron at least)00:29
TuvixYea, I was just about to wonder what the varients are doing here.00:29
TuvixI guess we're still a couple months (if you believe the PR) from knowing what an Omicron-targeted mRNA looks like in terms of initial results, and then more months away from knowing if it wanes the same.00:30
LjLi guess i should look at Delta and previous company too to "understand" things. but i focus on Omicron because that's what we have and my brainspace is limited :P00:30
TuvixYup, and loking at Italian impact, Omicron was much worse on all accounts, so it's reasonable to be more focused on this.00:30
LjLTuvix, a couple of months for Pfizer, more than that for Moderna. i suspect eventually both of them will be ready by June to August ;(00:30
LjLNovavax may be ready by April or May00:31
LjL... 202300:31
BrainstormNew from Ars Technica: Science: COVID’s spread within hospitals hit all-time high amid omicron wave → https://arstechnica.com/?p=183595600:32
de-factohere they start now with Novavax00:32
LjLoh, it exists? :P00:33
de-factodelivering to federal states... today00:34
de-facto%title https://www.reuters.com/business/healthcare-pharmaceuticals/germany-expects-novavax-vaccinations-start-this-week-2022-02-21/00:35
Brainstormde-facto: From www.reuters.com: EU, Germany expect Novavax deliveries to begin this week | Reuters00:35
LjLcool00:35
TuvixInteresting to look at the factors pointed out by that ARS article above regarding the hospital spread data analysis; it points to possible in-hospital spread causes that may include time in crowded waiting rooms due to hospital pressure plus lack of masking enforcement.00:37
LjLlack of masking enforcement *in hospitals* is just surreal00:38
TuvixThat's especially troubling since in 2 years, the US continues to do exceptionally badly with hospital & ICU metrics during surges.00:39
TuvixWell, it's not unique to hospitals; mask enforcement is bad everywhere.00:39
TuvixBack in June last year I carefully went to a couple dining joints during slow-hours. One was in an airport and officially staff had to be masked at all times there; it was largely for show, and they frequently wouldn't. Customers were to be masked when not actively eating or drinking, but nearly no one did.00:40
de-factoTuvix, do you think potentially higher contamination doses (due to not wearing masks, instead of improperly wearing masks or no good masks) may play a role in US COVID severity?00:41
BrainstormNew from ##covid-19 resources: ljl-covid: Add more vaccine keywords → https://github.com/ljl-covid/links/commit/a261c018e3f30b443fcfb9d25629159bb7045bc700:41
TuvixI only stayed for a plate of food & a drink typically, but I at least arrived with my mask per the rules. Then when Delta came (and no doubt the rules were as-badly if not more-poorly enforced) I stopped completely, realizing that kind of venue was less safe.00:42
Tuvixde-facto: Possibly? I think with Omicron now, the lack of high-quality masks being commonplace may be a factor too, but the recent mask publication shows that even a surgical-style mask has _some_ value, just not as good as a KN95/N95.00:43
TuvixI'd put vaccines as a bigger contributing factor, and a close 2nd being the social expectation we have here that we can largely do what we want without regard for the imapct on others or society.00:43
ecksprobably 90% of my patients last fall asked if they could un-mask the second they entered the room00:44
de-factojust was a spontaneous idea, not sure if it makes sense, but i know that contamination dose was discussed as one factor for correlating with severity00:45
LjLoh i forgot i have this fancy-looking italian-made mask here i wanted to look up00:45
TuvixRight, and not just severity, but even how good of an immune response you get from the infection (largely applies more the unvaccinated who are expecting that any exposure and/or positive test makes them immune, which we know to be untrue.)00:45
TuvixSince we know the dose matters for the type of immune response you get, if your goal is to have the most mild case of infection if you are exposed, it follows that reducing your viral load intake would be wise.00:46
LjLit looks like it's a company that didn't normally make masks at all. which isn't surprising, many companies "converted", but it's a bit surprising it's an FFP2 mask that at least *looks* fancier than the usual stuff, and that it comes from an italian company in 2022 rather than makeshift stuff from 202000:46
Tuvixecks: That follows my experience at a sports club (so not a clinical setting) where people ditched the masks as soon as they could. One even refused to continue to mask when the rules changed (per CDC changes last summer) and he, as an unvaccinated person, shouldn't have gone maskless.00:47
TuvixHe did anyway, as did the other unvaccinated people. He was a "core staffer" at the all-volunteer group, so he basically bullied the owner into ignoring the rules. Why have rules when you can just ignore them with impunity? :(00:48
TuvixThat's a very "American" attitude, sadly.00:48
LjL-Matrixde-facto: doesn't this look kinda like an Aura (but different)? Including the straps and the "fat" nose strip, which I *think* also has some foam or some kind of cushioning but I'm not really sure, I don't want to open it yet00:52
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* LjL-Matrix uploaded an image: (206KiB) < https://libera.ems.host/_matrix/media/r0/download/matrix.org/hmLZVtiknmsJYmMvFOXVLVTI/IMG_20220223_004929.jpg >00:52
* LjL-Matrix uploaded an image: (51KiB) < https://libera.ems.host/_matrix/media/r0/download/matrix.org/RHbIZooGROVnWlZRUIsNhtIX/IMG_20220223_005129.jpg >00:52
* LjL-Matrix uploaded an image: (61KiB) < https://libera.ems.host/_matrix/media/r0/download/matrix.org/nyQDfyAMioYCYAygocMMdOih/IMG_20220223_004854.jpg >00:52
de-factoyes it looks a bit like AUra, but the geometry is not exactly the same i guess00:53
LjLCE 0426 is Italcert, an Italian certification laboratory (unsurprisingly enough maybe)00:53
LjLde-facto, well it's interesting because i haven't really seen many masks that were anything like Auras, except the "Korean-style masks" but they're much much flimsier, only the shape is similar00:54
de-factomaybe its patented design or such?00:57
de-factohence can not exactly be copied ?00:57
LjLi don't know, but i suspect it's just more expensive design00:58
de-factoi stampled my Auras at work the third time today00:58
de-factoits always those damn rubber straps that rip off the metal clamps00:59
LjLah, wait, i was on the wrong website -.- this company *does* make masks as its main business00:59
de-factoi now wrapped the rubber straps in paper prior to stampling them with new clamps, maybe that helps a bit00:59
de-factoi think its due to the sharp edge on the metal clamps00:59
LjLthey also make reusable respirators, full-face ones too00:59
LjLhttps://www.blsgroup.com/00:59
LjLthese look like the one i have https://www.blsgroup.com/en/prodotti/bls-600/01:00
de-factothis here? https://www.blsgroup.com/en/prodotti/bls-600/01:00
de-factoah yeah01:01
de-factoi never read before i press enter01:01
de-factonever ever01:01
LjL"The mask is suitable for different physiognomies" ← get a translator who speaks real english01:02
LjL;)01:02
LjLi wonder why they make all four main styles ("Chinese", "Korean", "Aura", and uh cup)01:04
de-factotheir FFP3 option is not valveless though01:04
LjLjust because different people prefer different styles? even though these are very much targeted to workers?01:04
de-factoi wear a valveless FFP3 the whole day01:04
LjLor is there pros and cons of each01:04
de-factoso its just FFP2 that is valveless it seems01:05
de-factowith their portfolio01:05
LjLde-facto, are you sure? it says *that* model (600, not 690) is available as FFP2 and FFP301:05
LjLyou're getting it from the pictures?01:05
de-factofrom the "series models" tab table01:06
de-facto670 valveless 680 and 690 with valve01:06
LjLuhm you're right01:07
LjLi guess they think they can't provide FFP3 with the required air resistance without adding a valve01:07
de-factoso you got exactly the correct model there at your desk01:07
de-factoyeah possibly01:07
LjLde-facto, well, it was given to me by a hospital worker, who in turn got it at her hospital, but she isn't comfortable with this model so she's not wearing it. although "hospital" doesn't say much since they had terrible masks sometimes... but they'd definitely not get valved masks01:08
de-factoidk this one looks quite fine to me from what i could see01:09
de-factoit probably also got the problem with ripping rubber straps, but that can be solved i guess01:09
de-factoLjL,  are those rubber or fabric straps?01:10
LjLnot entirely clear to me what the difference is with the 700 model. "it's larger" is pretty much what the description boils down to01:10
LjLthey are rubber sadly01:10
LjLsimilar to Aura ones, maybe a bit wider though01:10
LjLquite thin01:10
BrainstormNew from COVID on Twitter: Marc Veldhoen (@Marc_Veld): -But: boosting with a 3rd vaccine dose increased antibody levels 10- to 100-fold, a 4th exposure in individuals with higher pre-boost antibodies resulted in less robust boosting (~5- to 10-fold).The C19 vaccine is a 3 dose, reaching optimal levels of antibodies [... want %more?] → https://twitter.com/Marc_Veld/status/149627355905177190501:10
de-factothe rubber material got the advantage that it does not slip over the hairs, so thats good01:12
de-factoi am not sure if a fabric one may just slip over the head and then end on the ears anyways just by movement01:12
de-factothe only disadvantage from the rubber ones are the fixing with metal staple clamps, that should get improved somehow (to a non-local fixing area, i tried that by wrapping the rubber straps in paper then stapling that)01:14
de-factonot sure, have to see if that holds longer01:14
LjLthe very first mask i had came with straps that made sense to me. kind of similar to this model https://www.blsgroup.com/prodotti/bls-o2-512-513/ in that it's basically just one strap that goes all around the mask, and "slides" inside the mask, which is very neat if it actually slides well because instead of having to tense the straps a lot to put it on, you just slide it first so you can easily put it around your neck, and then tense the other end to put it01:14
LjLaround your head01:14
LjLbut i didn't have enough foresight to keep that mask, so i don't know what mask it was01:15
LjLit was the only FFP2 mask the pharmacy had (€13!) before a long period of masks being impossible to find :\01:15
LjLit was a "cup" style, but with a valve01:16
de-factoi have also seen some design where they use the *masks* fabric to wrap that around (180 degrees) and staple the *masks* fabric around the rubber that just goes through that loop from mask fabric01:16
LjLback then nobody cared yet if they had a valve or not, although they started caring pretty quickly01:16
LjLde-facto, yes that's exactly what that one did01:16
LjLthe rubber slides through the loop01:16
de-factothat is much smarter probably because the PP fabric is much more durable and the contact area with the rubber straps bigger, hence much less prone to ripping off01:16
LjLand so it's one big piece, not two pieces, and you can put it on much more comfortably01:17
de-factoand since the PP fabric is soft it does not see *any* sharp edge where the rubber could rip01:17
TuvixMy nice re-usable one with flexible TPU fitting around the mouth & nose had a bit of a moisture problem, but that's mostly resolved with an accessory I added to my last filter refill order; it's basically just a sponge that goes around the edge of the mask interior to soak up moisture from breathing.01:17
de-facto(then they really may last long, hence possibly they sell less of such durable designs compared to a design that breaks after a while?)01:18
TuvixI really like the fit though, since the breathe99 mask now comes standard with an adjustable cloth strap and tensioner, so you wear the straps around the head and adjust them so they fit without being hard to wear.01:18
LjLTuvix, i don't really get how it can be highly reusable without a valve (or several)... the respirator dTal has comes with reusable filters but that comes at the expense of definitely needing valves to avoid moisture01:18
TuvixI mean, the filters are replaced, and anything else can be washed if soiled.01:19
TuvixShort of actual soil damage, I just let it air-dry (typically I have 2 to 3 days between uses already) and just replace filters after enough sustained use to require it.01:19
LjLit probably wouldn't get an actual N95 or similar certification while claiming it can be used for longer than 8 hours and/or reused but lacking valves to protect the filters from moisture01:21
TuvixIt'd be interesting to see some more tests done with filter quality evaluate after some hours of sustained use, not just the lab-tests done by a decent university around here.01:23
TuvixI don't wear this for long enough for sustained wear to matter, typically just whem I'm indoors and can't avoid being around other people.01:23
TuvixPerhaps 45 minutes to an hour at most, and that's if I keep it on for a couple back-to-back errands.01:24
TuvixThe moisture is now more or less contained in the sponge, while before it would build up on the TPU interior. What effect that has on the filter material, at least until it dries, I don't know, or how that compares to the typical N95 mask which is worn in much more physically demanding jobs than my strolling through the grocery store.01:25
de-factomaybe it also could be solved by getting some robust fabric, folding it back onto itself to form a loop for holding the rubber, then staple that onto the masks fabric01:25
TuvixThe mask is all plastic, although the exterior (which holds the straps to the exterior of the form) is cloth.01:26
TuvixWell, plastic/TPU.01:26
Tuvixhttps://breathe99.com/pages/technology (scroll down midway to get a view of the shell from both inside & outside)01:26
TuvixOh, they do test moisture via the breathability I think.01:28
TuvixSee section V of the whitepaper linked on that page; they talk about the mmH2O used to simulate "light" and "heavy" breathing.01:28
LjLTuvix, well but one thing is doing that to measure breathability, another is testing whether after some given number of hours of "heavy breathing" (or just moisture from normal breathing), the filtration efficacy is still relatively intact01:31
TuvixRight, they didd that too, see "VI. Extended Use Simulation" (page 4)01:32
LjLbut was moisture used? it says NaCl particles, how was water involved? the whitepaper never mentions the terms moisture, water, humidity... which is a bit concerning01:33
TuvixmmH2O is mm of water column at a given temp/pressure gradient.01:34
LjLthat's just a pressure unit01:34
LjLit doesn't mean H2O is being used01:34
dTalLjL: GVS do a valveless "source control" version of the mask I have01:35
TuvixOh, I skimmed the test paper I had too quickly; you're right, that'd be g/m2/24h or such.01:35
LjL%wik Centimetre or millimetre of water01:35
dTalwhich seems like a terrible idea, but it can't be completely useless01:35
BrainstormLjL, from English Wikipedia: A centimetre or millimetre of water (US spelling centimeter or millimeter of water) are less commonly used measures of pressure derived from pressure head. → https://en.wikipedia.org/wiki/Centimetre_or_millimetre_of_water01:35
Tuvix(different paper that talks about mmH2O vs. g/m2/24h standard.) So, I dunno. I do like that the moisture issue is largely solved for me, which presumably means I'm exposing the filters to less of it.01:36
LjLdTal, million dollar question, were they already making it before COVID and before valved masks became a big no-no in the collective consciousness? ;)01:36
dTalI believe not :)01:36
dTalit took them about a year of pandemic to roll out in fact01:36
dTalthe design is clearly adapted from the valved version, and in fact is difficult if not impossible to distinguish visually01:37
LjLdTal, there's probably only so many times you can send "no, and for a good reason" emails until you go "yes, and good luck"01:37
LjLtbf though this breathe99 thing seems like it beats GVS in the low profile race, and indeed mask waste will be a huge problem so it would be nice if more people adopted reusable ones, which for better or worse, will mean valveless ones, and ones that don't look from out of a doomsday movie01:39
TuvixYup, the cloth knit exterior piece that holds the straps actually looks OK when worn, without giving the "look at my medical PPE" look to it.01:40
dTalaround here, wearing any sort of reusable filter mask marks you out as a worry-wart01:40
TuvixI mean, ultimately N95 masks have the same issue of moisture build-up, at least if you do a proper fit-test to avoid escape around the edges. Perhaps there more filter material to disperse the outflow of air into, but for this mask I have that really just means you end up needing to replace the filters more often if you use them more.01:41
dTalthere's 3 tiers of mask wearing - useless surgical mask ("I'm being required to wear a maskk and I didn't prepare"), stretchy/cloth mask ("I am a reponsible citizen doing my part"), and valved respirator ("I have anxiety")01:42
TuvixThey've got a baseline guide of when to replace the filters based on your planned use, but really I just replace them after about a month or sooner if they're becomming harder to breathe through.01:42
LjLvalved ones are virtually unseen here (which is reflected on their lower prices :\)01:43
LjLTuvix, that sounds like too long tbh01:43
TuvixI only go out about once every 2 weeks these days :\01:44
LjLfair enough then :P01:44
dTalyeah I've only ever seen one other guy socially with a valved respirator01:44
TuvixShop for 2 weeks worth of food, check the PO box and maybe another errand or 2, if I'm feeling stir-crazy maybe pick up some to-go food and then park the car for another 1-2 weeks.01:44
LjLhttps://web.archive.org/web/20220220173743/https://www.businessinsider.com/disposable-face-mask-waste-toxic-poison-water-nanoplastics-pollution-health-2022-2?r=US&IR=T01:44
dTaland his was ostentatiously large01:44
LjL"The plastics industry saw COVID as an opportunity," John Hocevar, the oceans campaign director at Greenpeace USA, told me from his office in Washington, D.C. "They worked hard to convince policymakers and the general public that reusables were dirty and dangerous, and that single-use plastic is necessary to keep us safe."01:44
LjLThe fear-mongering worked. The global consumption of single-use plastics has increased by up to 300% since the pandemic began, according to a 2021 Organisation for Economic Co-operation and Development report.01:45
LjLso much for the EU's planned withdrawal of single-use plastics :\01:45
LjLAfter submerging the masks in water and letting them sit, Sarp and his team discovered both micro- and nanoplastic particles released from every single one.01:46
LjLThe masks were also found to expel nanoparticles of silicon and heavy metals like lead, cadmium, copper, and even arsenic.01:46
LjLyikes :|01:46
LjLwhy on earth01:46
LjL"The masks were also found to expel nanoparticles of silicon and heavy metals like lead, cadmium, copper, and even arsenic."01:49
LjLerr01:49
LjLi hate Wayland copypaste01:49
LjLi meant "But nanoparticles — of plastic, silicon, or other materials — are so minute in size that they can breach cell walls and damage DNA, affecting both human and nonhuman life-forms at the cellular level. Recent research on silicon nanoparticles, in particular, has shown that if a particle is very small in nano scale, it can act almost as a tiny, carcinogenic bomb."01:49
LjLand the link to "carcinogenic bomb" is this report https://www.umweltbundesamt.de/sites/default/files/medien/378/publikationen/texte_50_2014_carcinogenicity_and_mutagenicity_of_nanoparticles_1.pdf but Umwelt Bundesamt which i assume de-facto has heard of since it appears to be the German equivalent of the EPA01:50
LjLto be fair though this never seems to mention "plastic", silicon yeah01:52
LjL(tbf the article does say "The presence of silicon nanoparticles was of particular concern.")01:52
TuvixSpeaking of avoiding single-use waste-producing items, I need to order a new coffee travel mug. Whatever the liner is on my old one didn't survive the last soak & wash cycle :\01:53
TuvixI'm always tempted to buy coffee via drive-through if I can't have my trusted mug in the cup-holder when driving more than about 100km ;)01:54
TuvixI guess those are at least made from partially recycled paper, but I think the tops are almost always plastic.01:55
LjLaside from the waste and environmental concerns though, if potentially carcinogenic particles are released when submerging the masks or similar, i'd imagine they're also released when breathing through them. i hope we won't find outself with cancer spikes due to dodgily mass produced masks, among many other things we'll be facing...01:59
LjL(like, you know, the world ending and stuff)01:59
TuvixI've one of those weird people who always (well, okay, almsot always) wash new clothes before I wear them for similar reasons. I'd just as soon ensure any industrial bits used in their creation get a chance to avoid extended contact with my skin.02:02
LjLi do think we need to massively improve building air circulation/purification systems. we can't rely on masks in the longer term without making damage of various sorts02:03
LjLwell, we can't wash masks before use ;(02:03
LjLor at least, i'd strongly advise against it02:03
TuvixYea, that too; masks are a mitigation, not an answer, and one that we presumably want to avoid feeling compelled to use almost any time we go out.02:03
TuvixMy mask is as 2nd nature to me right now as my shoes; I'd like it to feel more like an umbrella that I take out only if there's a raised threat.02:04
LjLand the environmental concerns are *huge* anyway. we could look the other way for two years, maybe we will for another year or so, but damn it's a LOT of plastic02:04
TuvixThe reality at this point is everything is a mitigation, including vaccinations if you look at it like that. None of these alone are the magic answer, but they all combine to make any new surges or recovery from this recent Omicron hit a bit less deadly and problematic.02:05
TuvixAnother boost, hopefully with an updated vaccine that shows more VE against new VoCs? Well, sure, but that alone isn't the answer either. I don't want another Delta/Omicron like summer/winter this coming year, at least not like the US saw.02:06
LjLbut each mitigations has its costs, and some can be borne forever maybe, others not so much02:06
LjL<CarlSagan> [NPR - Science] Who might benefit from a 4th shot — and who might not https://www.npr.org/sections/goatsandsoda/2022/02/22/1029057935/who-might-benefit-from-a-4th-shot-and-who-might-not02:09
LjL"Although the extra shot boosted antibody levels to about the level observed right after the third shot, the rise in antibodies didn't translate into strong protection against infection. The extra dose reduced the risk of an infection by only about 10% to 30%, Regev-Yochay and her team report. During the 30-day study period, about 20% of the people who received the extra shot became infected with the omicron variant of the coronavirus, compared with about 25% of02:09
LjLthe people who received only three shots. The extra dose also didn't appear to activate T cells, which are critical for clearing out a future infection."02:09
BrainstormUpdates for Hong Kong: +6211 cases, +36 deaths since a day ago — Canada: +7702 cases, +70 deaths since 9 hours ago — Germany: +158268 cases since 23 hours ago — United Kingdom: +41524 cases since 23 hours ago02:10
de-factowhat were do the nanoparticles come from?02:10
TuvixAt this point I don't think re-boosting without targeting the latest VoCs makes much sense unless people aren't up to date on vaccinations yet.02:11
TuvixAlthough the VE against the Beta-specific vaccines wasn't as good as was hoped, so I don't really know what the impact will be, but the real question is how it works with the yet-to-be-seen next big thing.02:11
LjLde-facto, i don't really know, production processes?02:50
de-factoi mean where do humans get exposed to them02:52
BrainstormUpdates for Nicaragua: +109 cases since 5 days ago03:00
LjLde-facto, it's about masks03:05
LjLde-facto, started from this article https://web.archive.org/web/20220220173743/https://www.businessinsider.com/disposable-face-mask-waste-toxic-poison-water-nanoplastics-pollution-health-2022-2?r=US&IR=T03:05
LjL(archive because paywall)03:05
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): I’ve yet to see any clinical data, regarding severity of illness, reinfection, or protection by vaccines, that suggest BA.2 is different or worse than BA.1, despite its different mutations (antigenic distance) and the results from the Syrian hamster model. → https://twitter.com/EricTopol/status/149631381243313357003:43
de-factoLjL, yeah but is it about decomposing masks or the ones that are worn?03:49
LjLde-facto,03:51
LjLAfter submerging the masks in water and letting them sit, Sarp and his team discovered both micro- and nanoplastic particles released from every single one. The leachate from those masks — that is, the particles they emitted into fluid — amounted to a sort of toxic tea.03:51
LjLThe masks were also found to expel nanoparticles of silicon and heavy metals like lead, cadmium, copper, and even arsenic. Sarp says that he was astonished by what he and the team found after a relatively brief period of submersion, and by the quantity of particles released by each mask. The masks released hundreds, and sometimes thousands, of toxic particles — particles that can potentially disrupt entire marine food chains and contaminate drinking water.03:51
LjLso it's not a test on ones that are worn, but it's not about letting them decompose either. just what they release when in water03:52
BrainstormNew from COVID on Twitter: Scott Gottlieb, MD (@ScottGottliebMD): More evidence to suggest that infection with Omicron BA.1 variant confers a period of immunity that protects against subsequent infection with BA.2. Other evidence suggests that a boosted vaccine delivers equal, and perhaps slightly better [... want %more?] → https://twitter.com/ScottGottliebMD/status/149631595761416192203:53
de-facto  hmm i am too tired to read the whole article, i just wanted to know if one inhales that or not03:55
LjLit doesn't say that but it just seems likely enough to me03:57
LjLat least if the mask gets went inside03:57
LjLbut the purpose of the tests was not to measure direct danger to humans by inhalation, but mainly danger to the environment (so, masks in the sea)03:58
LjLbut if those non-plastic nanoparticles are in the masks, it's not the mask decomposing, it's other materials that are presumably already there before being in the water03:59
de-factohmm but where would they come from? colored masks?04:00
de-factolike the dye?04:00
LjLi guess i wouldn't mind seeing a study on lung cancer incidence among people who wear masks as part of their work. although it would be very hard to tell distinguish from mask-induced and work-induced issues04:00
de-factoi think we would know by know if e.g. medical personnel would have elevated rates for that, those folks know a thing or two about statistics04:01
LjLmost medical people didn't routinely wear masks for prolonged periods of time before COVID... except surgeons i guess, but those masks are very different from the FFP2 masks we're wearing04:01
de-factowell are they? id assume they also use the PP fabric etc04:03
de-factoid be interested in the mechanism they propose, e.g. if some physical degradation of the PP fabric takes place due to some process, or if they had dye on it04:04
de-factowhat if its the printed ink outside that does normally not reach the inside but maybe dissolve in water?04:05
de-factoor what if its some process that makes the fibers brittle?04:06
de-factoone would have to know exactly what they did there, in every detail04:07
* de-facto is half asleep already04:08
LjLde-facto, well this is the study https://www.sciencedirect.com/science/article/abs/pii/S0043135421002311 i presume it has details but we might leave it for another day ;P04:42
LjLwell, except it's not open access04:43
de-factoyeah dye i guess04:57
LjLwhat about silicon? is that in dye? that's stated as the biggest concern (nanoparticles of silicon)04:58
BrainstormUpdates for South Korea: +171448 cases, +99 deaths since a day ago05:05
LjLouch05:06
de-factonot sure05:06
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): Hard to beat a 99.2% 3-shot vaccine effectiveness vs Omicron hospitalization in this new @NatureMedicine report from @KPSCalResearch 2-shot 84.5% (95% CI 23,97)3-shot 99.2% (95% CI 76,100)nature.com/articles/s4159… → https://twitter.com/EricTopol/status/149634791616821248106:06
BrainstormUpdates for New Zealand: +3181 cases, +27550 tests (11.5% positive) since a day ago06:07
BrainstormUpdates for Novosibirsk, Russia: +5128 cases, +16 deaths since a day ago — Bashkortostan, Russia: +4302 cases, +19 deaths since a day ago — Pulau Pinang, Malaysia: +2601 cases, +3 deaths since a day ago — Kedah, Malaysia: +2583 cases, +3 deaths since a day ago07:10
BrainstormNew from r/Coronavirus: Coronavirus: 'We're doing everything we can to survive': High-risk, disabled Americans feel forgotten → https://old.reddit.com/r/Coronavirus/comments/sz90t1/were_doing_everything_we_can_to_survive_highrisk/07:31
BrainstormUpdates for Cook Is.: +2 cases, +252 tests (0.8% positive) since 4 days ago08:00
BrainstormNew from MedicineNet: (news): Working Out After Your COVID Shot Might Boost Immunity → http://www.medicinenet.com/script/main/art.asp08:58
BrainstormUpdates for New Caledonia: +6084 cases, +12 deaths since 2 days ago09:02
BrainstormNew from r/Coronavirus: Daily Discussion Thread | February 23, 2022: Please refer to our Wiki for more information on COVID-19 and our sub. You can find answers to frequently asked questions in our FAQ , where there is valuable information such as our: → https://old.reddit.com/r/Coronavirus/comments/szbzex/daily_discussion_thread_february_23_2022/09:07
BrainstormNew from Reddit (test): CoronaVirus_2019_nCoV: BA.2 omicron subvariant’s swift rise to dominance in Gothenburg wastewater: the virus level is still higher than the previous record measurements obtained in the first, second, and third waves of the pandemic → https://old.reddit.com/r/CoronaVirus_2019_nCoV/comments/szc3jp/ba2_omicron_subvariants_swift_rise_to_dominance/09:26
BrainstormNew from Reddit (test): CoronavirusUK: UK lost up to £16bn due to fraud and error in Covid loans schemes → https://old.reddit.com/r/CoronavirusUK/comments/szc5im/uk_lost_up_to_16bn_due_to_fraud_and_error_in/10:04
BrainstormNew from StatNews: STAT+: FDA asks Congress for more power to regulate certain diagnostic tests, including prenatal screenings: The FDA wants clearer authority over certain diagnostic tests, including prenatal screenings. Right now, it [... want %more?] → https://www.statnews.com/2022/02/23/fda-asks-congress-for-more-power-to-regulate-certain-diagnostic-tests-including-prenatal-screenings/11:03
BrainstormUpdates for Germany: +219377 cases since 20 hours ago — United Kingdom: +759 cases since 15 hours ago — Canada: +71 deaths since 18 hours ago11:07
B0B1Keep faith and watch https://rumble.com/user/invisiblewar11:11
BrainstormNew from BMJ: David Oliver: Has covid killed the medical conference?: Healthcare conferences in real life venues, with presenters and delegates physically present, have been cancelled or moved to online since the pandemic started. I loved these events. I miss them. And... → http://www.bmj.com/content/376/bmj.o412.short11:12
BrainstormNew from Reddit (test): Global COVID Cases For 23FEB22: US RO Estimate, Case Count & Charts: Information thru: 22FEB22 → https://old.reddit.com/r/nCoV/comments/szef9v/global_covid_cases_for_23feb22/11:41
BrainstormNew from COVID on Twitter: Jeffrey Barrett (@jcbarret): Every day at 9am there's an auto-email summarising lineages from the 8-10 thousand SARS-CoV-2 genomes sequenced in the previous 24 hours @sangerinstitute. The Delta number has been bouncing around in single digits, and today was the first day with zero. ☠️ → https://twitter.com/jcbarret/status/149644095010886860812:11
BrainstormNew from COVID on Twitter: Covid Fact Check UK (@fact_covid): It appears Delta has been all but eradicated in the UK - completely vanquished by the Omicron variant. twitter.com/jcbarret/statu… → https://twitter.com/fact_covid/status/149645084225331610112:50
BrainstormUpdates for Indonesia: +61488 cases, +227 deaths, +519532 tests (11.8% positive) since 23 hours ago13:06
BrainstormNew from Reddit (test): nCoV: Protesters, police clash in New Zealand | 24FEB22 → https://old.reddit.com/r/nCoV/comments/szgkg0/protesters_police_clash_in_new_zealand_24feb22/13:48
BrainstormNew from Reddit (test): nCoV: COVID-19 live updates: Protest organizer denied bail | Estimates show drop in Alberta hospitalizations; EPS issue 100+ tickets during Tuesday convoy; Boris Johnson ends all COVID restrictions in the U.K | 22FEB22 → https://old.reddit.com/r/nCoV/comments/szgsrp/covid19_live_updates_protest_organizer_denied/13:57
BrainstormNew from Reddit (test): nCoV: Hong Kong: What went wrong with its Covid plan? | 23FEB22 → https://old.reddit.com/r/nCoV/comments/szguhl/hong_kong_what_went_wrong_with_its_covid_plan/14:07
BrainstormUpdates for Brunei: +3285 cases since a day ago14:08
BrainstormNew from Politico: Poland lifts all but basic coronavirus restrictions: Restrictions on numbers in shops to be lifted and nightclubs to reopen March 1, but facemasks and isolation requirements remain. → https://www.politico.eu/article/poland-lifts-all-but-basic-coronavirus-restrictions/14:16
BrainstormNew from COVID on Twitter: Carl Zimmer (@carlzimmer): Sanofi’s Covid protein vaccine at last delivers Phase 3 results. 57.9% against symptomatic covid, 100% against severe covid and hospitalization. Plus strong antibody responses from boosters, regardless of original vaccination  sanofi.com/en/media-room/… → https://twitter.com/carlzimmer/status/149647630555413299714:36
BrainstormUpdates for Germany: +207278 cases since 22 hours ago15:11
BrainstormNew from StatNews: Pharma: STAT+: Pharmalittle: South African advocacy group sues to see Covid-19 vax contracts; Sanofi and Glaxo seek approval for their Covid shot → https://www.statnews.com/pharmalot/2022/02/23/covid19-vaccine-africa-sanofi-glaxo-pfizer-abortion/15:25
BrainstormNew from Novavax: (news): Novavax Announces Shipments of its COVID-19 Vaccine to European Union Member States → https://ir.novavax.com/2022-02-23-Novavax-Announces-Shipments-of-its-COVID-19-Vaccine-to-European-Union-Member-States15:44
BrainstormNew from COVID on Twitter: Tulio de Oliveira (@Tuliodna): Then another major surprise and another variant of concern (Omicron), which quickly take over all infections in South Africa and the world. pic.twitter.com/qooKA1pUfO → https://twitter.com/Tuliodna/status/149649625554299699415:54
BrainstormNew from COVID on Twitter: Marc Veldhoen (@Marc_Veld): Got a COVID19 booster? You probably won´t need another one for a long time (or ever; unless due to unexpected health issues)nytimes.com/2022/02/21/hea… → https://twitter.com/Marc_Veld/status/149650473963852595416:23
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): For @techreview's 2022 top 10 breakthrough technologies, Covid genomic surveillance, Paxlovid, #AI protein folding and AI synthetic data are among them@DeepMind @antonioregalado @strwbillytechnologyreview.com/2022/02/23/104… pic.twitter.com/QG4Jyo72Dy → https://twitter.com/EricTopol/status/149650709171189760316:33
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): The mixed findings as to whether the Sotrovimab monoclonal antibody works against the BA.2 variantnature.com/articles/d4158… but it appears that Bebtelovimab does @nature by @FKreier pic.twitter.com/d762qFqnzu → https://twitter.com/EricTopol/status/149651287436129075217:02
BrainstormUpdates for Canada: +9302 cases, +92 deaths since 23 hours ago17:03
BrainstormNew from ClinicalTrials.gov: (news): Endothelial Protection in Convalescent COVID-19 Patients → https://clinicaltrials.gov/ct2/show/NCT0525292317:12
de-facto%title https://depositonce.tu-berlin.de/bitstream/11303/16461/4/2022-02-23_MODUS-COVID_Bericht.pdf  "MODUS-COVID Bericht vom 23.02.2022" about BA.2 resurge in Germany from https://depositonce.tu-berlin.de/handle/11303/1646117:14
Brainstormde-facto: From depositonce.tu-berlin.de: MODUS-COVID Bericht vom 23.02.2022 (Müller, Sebastian Alexander; Charlton, William; Conrad, Natasa Djurdjevac; Ewert, Ricardo; Paltra, Sydney; Rakow, Christian; Conrad, Tim; Schütte, Christof; Nagel, [...]17:14
de-facto%title https://covid-sim.info/17:15
Brainstormde-facto: From covid-sim.info: COVID-19 DataViewer17:15
BrainstormNew from ClinicalTrials.gov: (news): COVID-19 Prevention Trial: Effect of Prophylactic Use of TAFFIX™ on Infection Rate by SARS-COV-2 VIRUS (COVID-19). → https://clinicaltrials.gov/ct2/show/NCT0525246817:22
de-facto%title https://www.biorxiv.org/content/10.1101/2022.02.14.480335v117:34
Brainstormde-facto: From www.biorxiv.org: Virological characteristics of SARS-CoV-2 BA.2 variant | bioRxiv17:34
de-facto%title https://www.medrxiv.org/content/10.1101/2022.01.28.22270044v117:35
Brainstormde-facto: From www.medrxiv.org: Transmission of SARS-CoV-2 Omicron VOC subvariants BA.1 and BA.2: Evidence from Danish Households | medRxiv17:35
LjL-MatrixNew from r/WorldNews: worldnews: Even small donation to Freedom Convoy after Feb. 15 enough to have donor's bank accounts frozen, finance committee told → https://www.reddit.com/r/worldnews/comments/szgfuc/even_small_donation_to_freedom_convoy_after_feb/17:44
LjL-MatrixArticle deleted from worldnews of course17:44
LjL-MatrixI'm starting to think left or right wing doesn't matter, governments are only too happy to use covid-related unrest to crush simple freedoms17:45
xxso you're coming over to our side then?17:45
BrainstormNew from ClinicalTrials.gov: (news): Association of the Risk for Thrombotic Thrombocytopenia Syndrome and Exposure To COVID-19 Vaccines → https://clinicaltrials.gov/ct2/show/NCT0525244217:51
LjLxx: doubtful17:56
LjLI've answered this way when I was asked before, a few times... COVID almost certainly wasn't "created" to crush anyone's freedoms, but governments almost always take any circumstance conducive to crushing freedoms as a good excuse to do so, so while I've been in favor of lockdowns and stuff, I've also being vocal that they should at some point end, that green passes should remain an emergency measure also with an end (and I've grumbled when the Italian government17:58
LjLuntied them from the emergency state although the emergency state must end now due to the constitution)17:58
LjLI think that a pandemic can create dynamics that end up oppressing people more than they were before, both politically and economically, is a bit of a given and if someone is outraged at me stating this simple general common sense reality, they can get fucked. And if they do get outraged, you can be the left wing ones will say I'm a fascist, and the right wing ones will say I'm a commie18:00
LjLBe sure*18:01
LjLand r/worldnews will say something like "I've mocked public health measures"18:02
BrainstormNew from COVID19 Vaccine Tracker: valerie: Altimmune Inc: AdCOVID → https://covid19.trackvaccines.org/vaccines/75/18:10
BrainstormNew from COVID on Twitter: Michael Lin, MD PhD  (@michaelzlin): Today's release actually provides some nice data that speaks to the age effect. You can see below in the gray bars (after primary vax series) that Sanofi-GSK is closer to Pfizer than J&J or AZ (note log scale) for 18-55yo, but is worse than all other [... want %more?] → https://twitter.com/michaelzlin/status/149653423188287079318:20
BrainstormNew from COVID on Twitter: Michael Lin, MD PhD  (@michaelzlin): So perhaps Sanofi-GSK's naked protein+adjuvant efficacy is more sensitive to immune function than the other vax types. That would mean the approach works, but dosing needed optimization through trial and error. The other vax were lucky not to run into [... want %more?] → https://twitter.com/michaelzlin/status/149653530754170470518:30
BrainstormNew from COVID on Twitter: Michael Lin, MD PhD  (@michaelzlin): Novavax had peak antibody levels between Pfizer and Moderna using half the amount of antigen. If Sanofi-GSK peak is also below Pfizer peak (again, can't say for sure), that would suggest Novavax's adjuvant is better, or its nanoparticle helps, or [... want %more?] → https://twitter.com/michaelzlin/status/149653871402511565318:39
BrainstormNew from COVID on Twitter: Michael Lin, MD PhD  (@michaelzlin): So perhaps Sanofi-GSK is still underdosed, but I'm sure they have their reasons for not going higher.Overall shows that while the science of vaccine-making is reliable in the long term, in the short term there is some luck and art to it. → https://twitter.com/michaelzlin/status/149653871592961228918:49
* enyc meows18:54
enycUK endemic covid-19 hrrm18:54
BrainstormUpdates for Italy: +49162 cases, +252 deaths, +479447 tests (10.3% positive) since 23 hours ago — Canada: +9877 cases, +96 deaths since 23 hours ago — United Kingdom: +840 cases, +783998 tests (0.0% positive) since 23 hours ago19:08
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): The Hospital at Home (HaH) movement is getting legs, propelled by Covid, and will be increasingly adopted with sensors, #AI analytics, validation. The @NHS is a leading force, as we laid out @NHS_HealthEdEngtopol.hee.nhs.ukft.com/content/76a8da… pic.twitter.com/vjukPrpPAP → https://twitter.com/EricTopol/status/149654582433117389019:08
LjLIf I wanted to stay so reliably between 10% and 11% positive rate as Italy has been doing I don't think I could even if I could decide how many tests to run...19:46
LjLIt's stayed at that even during low testing days whereas what it was always like before was big spikes up when testing went down19:47
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): It's not surprising that Iceland is lifting all Covid restrictions, but the rationale provided by their Ministry of Health is startling"as many people as possible need to be infected with the virus" —@WillumThorreuters.com/business/healt… @reuters @NSkyds → https://twitter.com/EricTopol/status/149655803789257114019:57
xx^ need to get as many people with long covid as possible19:59
LjLgoing from that tweet20:03
LjL%title https://twitter.com/mroliverbarnes/status/149649886517184512020:04
BrainstormLjL: From twitter.com: Oliver Barnes (@mroliverbarnes): "Iceland's government is not just lifting all Covid restrictions, they are saying it's about time for everyone to get infected..." | nitter20:04
LjL(check text quoted as image, sigh)20:04
LjLuhm i don't suppose Brainstorm's OCR thing still works20:04
LjL%title https://pbs.twimg.com/media/FMSheG7WQAINP73?format=png&name=small20:04
BrainstormLjL: From pbs.twimg.com: COPENHAGEN, Feb 23 (Reuters) - Iceland will lift all remaining COVID-19 restrictions on Friday, including a 200-person indoor gathering limit and restricted opening hours for bars, the Ministry of [...]20:04
LjLoh wow it does20:04
LjLi'm a genius20:04
LjL%print https://pbs.twimg.com/media/FMSheG7WQAINP73?format=png&name=small20:04
BrainstormLjL, It says: COPENHAGEN, Feb 23 (Reuters) - Iceland will lift all remaining COVID-19 restrictions on Friday, including a 200-person indoor gathering limit and restricted opening hours for bars, the Ministry of Health said on Wednesday. "Widespread societal resistance to COVID-19 is the main route out of the epidemic," the ministry said in a statement, citing infectious disease [... want %more?]20:04
BrainstormLjL, It says: COPENHAGEN, Feb 23 (Reuters) - Iceland will lift all remaining COVID-19 restrictions on Friday, including a 200-person indoor gathering limit and restricted opening hours for bars, the Ministry of Health said on Wednesday. "Widespread societal resistance to COVID-19 is the main route out of the epidemic," the ministry said in a statement, citing infectious disease [... want %more?]20:04
BrainstormLjL, It says: COPENHAGEN, Feb 23 (Reuters) - Iceland will lift all remaining COVID-19 restrictions on Friday, including a 200-person indoor gathering limit and restricted opening hours for bars, the Ministry of Health said on Wednesday. "Widespread societal resistance to COVID-19 is the main route out of the epidemic," the ministry said in a statement, citing infectious disease [... want %more?]20:04
LjLokay just once though20:04
xxso much mixed messaging "[...] as the vaccines are not enough"20:06
LjLthe vaccines are not enough, but infection doesn't provide much better immunity, while on the flipside, it provides, uh, infection20:07
LjLso yeah i dunno20:07
LjLbut maybe Iceland is just being more open and transparent about their motives than all the other countries that are also "reopening everything" ;(20:07
BrainstormNew from COVID on Twitter: Thomas House ( ˘▽˘)っ☕️ (@TAH_Sci): Please take the time to read about some of the amazing work that's been done to get us to where we are with the pandemic.wisecampaign.org.uk/covid-unsung-h… → https://twitter.com/TAH_Sci/status/149655886456892620820:36
BrainstormUpdates for Spain: +33103 cases, +307 deaths since 23 hours ago21:00
BrainstormNew from Il Sole 24 Ore: Quarta dose: chi sono i super fragili che potranno farla da marzo: Dopo il via libera dell’Agenzia del farmaco sono arrivate le indicazioni del commissario Figliuolo che fanno partire la nuova fase della campagna vaccinale → https://www.ilsole24ore.com/art/quarta-dose-chi-sono-super-fragili-che-potranno-farla-marzo-AEjAeOFB21:05
LjL%title https://twitter.com/zeynep/status/149650682162383258221:16
BrainstormLjL: From twitter.com: zeynep tufekci (@zeynep): "The Africa CDC is asking for a pause in vaccine donations. Distribution remains a challenge (and getting too much at once makes it harder to use them before they expire), [...]21:16
BrainstormNew from Pfizer: kimkevin: CDC Advisory Committee on Immunization Practices Votes to Recommend TicoVac™, Pfizer’s Tick-Borne Encephalitis (TBE) Vaccine, For Those at Risk of Virus Exposure → https://www.pfizer.com/news/press-release/press-release-detail/cdc-advisory-committee-immunization-practices-votes21:54
BrainstormUpdates for France: +60927 cases, +188 deaths since 23 hours ago22:02
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): Update with this new report for 3-shots vs Omicron infections, consistent evidence of benefit across 9 studies for ~50% VE, much lower than ~90%+), but higher than 2-shots, less protection over time twitter.com/EricTopol/stat… pic.twitter.com/Tzrh2vULgb → https://twitter.com/EricTopol/status/149658974139064729622:03
BrainstormNew from CIDRAP: News Scan for Feb 23, 2022: COVID vaccines and blood clots Digital health guidance for pandemics More high-path avian flu in US poultry Global flu continues decline → https://www.cidrap.umn.edu/news-perspective/2022/02/news-scan-feb-23-202222:42
BrainstormUpdates for Malaysia: +31199 cases, +55 deaths since a day ago — Germany: +220624 cases since 23 hours ago23:05
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): New @NEJM  The decoupling of infections from hospitalizations and deaths during the Omicron wave in South Africa: impact of a high rate of prior infection, some hybrid immunity, and the likely role of cellular immunitynejm.org/doi/full/10.10… pic.twitter.com/iubaNgOTW6 → https://twitter.com/EricTopol/status/149660590105404211823:11
BrainstormNew from COVID on Twitter: Marc Veldhoen (@Marc_Veld): Moderna goes to phase 3 with an RSV mRNA vaccinemRNA-1345 codes for the prefusion F glycoprotein, the best way to neutralise the respiratory virus.investors.modernatx.com/news/news-deta… → https://twitter.com/Marc_Veld/status/149660874398702797823:21
BrainstormNew from COVID on Twitter: Marc Veldhoen (@Marc_Veld): Info;900.000 gevaccineerden. vergeleken met SARS-CoV-2 infectienejm.org/doi/full/10.10… → https://twitter.com/Marc_Veld/status/149661184493663846823:31
BrainstormNew from COVID on Twitter: Marc Veldhoen (@Marc_Veld): Population Immunity and Covid-19 Severity with Omicron Variant in South AfricaThe "mildness" of Omicron; a combination of vaccine and prior infection. This decoupled infection from hospitalisation, not intrinsic pathogenicity of Omicron.nejm.org/doi/full/10.10… → https://twitter.com/Marc_Veld/status/149661792959662080423:51

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