libera/##covid-19/ Thursday, 2022-02-24

BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): What WAT? What BAT?A brilliant review of polychromatic fat tissue and the type that is at the heart of the obesity epidemic@NEJM by @acypess nejm.org/doi/full/10.10… pic.twitter.com/47IwnJCIYj → https://twitter.com/EricTopol/status/149662611620266803600:30
BrainstormNew from COVID on Twitter: Marc Veldhoen (@Marc_Veld): Also for this age group, vaccines work very well, but; 2 doses of the BNT162b2 vaccine were already highly effective against severe disease.Effectiveness of BNT162b2 Vaccine against Critical Covid-19 in Adolescentsnejm.org/doi/full/10.10… → https://twitter.com/Marc_Veld/status/149662960019303219500:40
BrainstormNew from COVID on Twitter: Marc Veldhoen (@Marc_Veld): Why the COVID-19 pandemic may have been the worst in modern history.gidmk.medium.com/has-covid-19-b… → https://twitter.com/Marc_Veld/status/149663198118620366300:50
BrainstormUpdates for Hong Kong: +8674 cases, +49 deaths since 23 hours ago — Tonga: +35 cases since a day ago — Greenland: +64 cases, +3 deaths since a day ago01:10
LjLhttps://www-punto--informatico-it.translate.goog/green-pass-base-arrivi-paesi-extra-ue/?_x_tr_sl=it&_x_tr_tl=en&_x_tr_hl=en&_x_tr_pto=wapp01:18
LjLno more vaccination requirement for people entering Italy from outside the EU01:19
LjL(a "basic green pass" is one that can be obtained with testing)01:19
LjL(including rapid antigen)01:19
LjLalso, from March 31 contacts of positives will no longer need to quarantine, FFP2 will no longer be required in schools, and the system of colored alert levels will go away01:21
de-factoback in the times when Delta still was circulating a friend of mine (double vaccinated) got COVID. She said she was warned by CWA, hence did a quicktest everyday and it was negative, even when symptoms already had began. then at day 5 the test became positive01:40
de-factoso allowing foreign travelers without any quarantine just with a negative quicktest will open up for mutants import01:40
de-facto*begun01:41
LjLtbf the positive rates with Omicron on quicktests are *much higher* in Italy01:42
LjLi'm not entirely sure what's going on... whether it's Omicron, or the test themselves, or people have gotten better at poking their nose01:42
LjLbut it went from <1% to ~10% even now that the spike "appears" to be going down01:43
LjLhttps://lab24.ilsole24ore.com/coronavirus/#box_6a  it's even going up01:45
LjLcomplete decoupling between PCR and antigen tests01:46
Brandon_I tested positive for covid 2 weeks ago and had no symptoms. could it have been a false positive?01:47
LjLa false positive on PCR is quite unlikely. a false positive on a rapid test is slightly more likely, but still unlikely. false negatives are much more likely.01:53
LjLon the other hand, asymptomatic COVID isn't uncommon01:53
BrainstormUpdates for Slovakia: +23086 cases since 23 hours ago — Canada: +9227 cases, +137 deaths, +146332 tests (4.2% positive) since 23 hours ago02:00
LjL<Brainstorm> New from BBC Health: Covid: End of legal need to self-isolate in England: All Covid legal restrictions are over in England, as part of the government's Living with Covid plan. → https://www.bbc.co.uk/news/uk-6050028702:06
LjLand so it happens02:06
LjL"The £500 self-isolation support payment for people on low incomes who test positive for Covid will no longer be available"02:06
LjLand from April 1, "The £500 self-isolation support payment for people on low incomes who test positive for Covid will no longer be available" so let's prepare to stop having our beloved numbers02:07
BrainstormNew from BBC Health: Covid: End of legal need to self-isolate in England: All Covid legal restrictions are over in England, as part of the government's Living with Covid plan. → https://www.bbc.co.uk/news/uk-6050028702:07
BrainstormNew from COVID on Twitter: Bloom Lab (@jbloom_lab): @PeacockFlu @emmecola @stuartjdneil @K_G_Andersen This is correct answer. The paper accurately states the chance of two random single 19 nucleotide sequences matching this #SARSCoV2 sequence is 3e-11. But that's not as impressive as it sounds. There are ~6e12 [... want %more?] → https://twitter.com/jbloom_lab/status/149666641481964749203:05
BrainstormNew from COVID on Twitter: Bloom Lab (@jbloom_lab): @PeacockFlu @emmecola @stuartjdneil @K_G_Andersen And even less impressive here, as only ~12 of the 19 nucleotides are unique to SARS-CoV-2, w flanking regions mostly shared w related viruses like BANAL-20-52 and RaTG13. So it's really just 12-nucleotide sequence [... want %more?] → https://twitter.com/jbloom_lab/status/149666782536408268803:15
BrainstormUpdates for South Korea: +170006 cases, +82 deaths since 22 hours ago04:04
BrainstormNew from r/COVID19: COVID19: Clinical and antibody characteristics reveal diverse signatures of severe and non-severe SARS-CoV-2 patients → https://www.reddit.com/r/COVID19/comments/szzjed/clinical_and_antibody_characteristics_reveal/04:42
BrainstormUpdates for New Zealand: +6130 cases, +33228 tests (18.4% positive) since 22 hours ago — United Kingdom: +40610 cases since 17 hours ago05:00
de-facto.title https://liveuamap.com/ things happening in Ukraine fucking NOT good05:14
Brainstormde-facto: From liveuamap.com: Ukraine Interactive map - Ukraine Latest news on live map - liveuamap.com05:14
LjLxx, you okay?05:50
xxvery tired because watching the news all the time but no explosions heard nearby05:50
xxinternet was out for a bit, but that was unrelated05:50
TuvixWow, I'll have to dig further, but this today's weekly CDC update just 9.2k new deaths for last month, and I'd assumed by watching prior trends that this would be largely complete with only a couple-thousand more at most added from here on out :\05:53
TuvixLooks like about a 15% rise (ranging from 13% - 18% depending on age-group) added to the Jan provisional death tolls.06:19
BrainstormNew from Science-Based Medicine: FTC targets physicians’ COVID claims with cease-and-desist letters: The FTC recently announced it had issued 20 more cease-and-desist demands to physicians and others claiming their products and services prevent or treat COVID-19 without [... want %more?] → https://sciencebasedmedicine.org/ftc-targets-physicians-covid-claims-with-cease-and-desist-letters/07:06
BrainstormUpdates for Germany: +328130 cases since 23 hours ago — Selangor, Malaysia: +7798 cases, +10 deaths since 23 hours ago — New Caledonia, France: +5948 cases, +12 deaths since 23 hours ago — Bashkortostan, Russia: +4261 cases, +19 deaths since 23 hours ago07:09
BrainstormNew from COVID on Twitter: Josiah 'So Mild' Grindrod (@JT_Grindrod): Triple vaxxed and you won't find many people on this site that take covid more seriously than I do.Delete this shit take. Even I would be far more concerned about a fucking aerial bombardment than covid in this situation. twitter.com/DanaHoule/stat… → https://twitter.com/JT_Grindrod/status/149673442326114304307:34
BrainstormNew from MedicineNet: (news): COVID Travel Rules to Europe May Be Lifted for Vaccinated → http://www.medicinenet.com/script/main/art.asp08:03
Brandon_It was a rapid test at my workplace08:03
TuvixYour positive test result? Rapid tests (RATs or "Rapid Antigen Tests") often have a notable false *negative* rate, and much less likely to show positive when the test is negative. A PCR-test to follow-up is sometimes called for, but many places aren't bothering.08:07
TuvixThe bigger issue is that especially with Omicron that's the main varient today it's more likely that you could get a negative test but be contagious since the antigen tests are quite a bit less sensitive than would be ideal.08:08
undefined_bobtrue :(08:09
BrainstormNew from r/Coronavirus: Daily Discussion Thread | February 24, 2022: Please refer to our Wiki for more information on COVID-19 and our sub. You can find answers to frequently asked questions in our FAQ , where there is valuable information such as our: → https://old.reddit.com/r/Coronavirus/comments/t05ixc/daily_discussion_thread_february_24_2022/09:09
BrainstormNew from BMJ: Seven days in medicine: 15-22 February: Covid-19Omicron booster study starts in UKA UK trial has been launched to test one of the world’s first covid vaccines specific to the omicron variant.1 The study, by Moderna and the National... → http://www.bmj.com/content/376/bmj.o442.short09:58
BrainstormUpdates for France: +911 cases since 12 hours ago10:04
BrainstormNew from BMJ: Ann Robinson’s research reviews—24 February 2022: Ivermectin to prevent severe covid-19?In wealthier countries there is now a range of drugs to treat high risk individuals who get covid-19, including antivirals such as nirmatrelvir-ritonavir,... → http://www.bmj.com/content/376/bmj.o444.short10:17
SpearRavenhttps://www.youtube.com/watch?v=OSvc5gFif8E10:20
BrainstormUpdates for Brunei: +3721 cases, +1 deaths since 20 hours ago11:06
BrainstormNew from Reddit (test): Covid2019: Kids Who Got COVID-19 Vaccine Greatly Reduced Their MIS-C Risk: Kids Who Got COVID-19 Vaccine Had Less Than 1 in Million Risk for MIS-C → https://old.reddit.com/r/Covid2019/comments/t07n74/kids_who_got_covid19_vaccine_greatly_reduced/11:25
TuvixSpearRaven: Sorry about that, I mistook the ad for the content. Seems most of that clip is about the importance of science in our studies and data, and opens with discussion of double-blind trials.11:25
* enyc wonders where this covid endemicity going etc11:52
TuvixWe're globally not close to finished dealing with Omicron's fallout yet. We might approach something better if this spring unfolds like last spring, but a varient or Omicron prooving less willing to go back to then-Alpha baseline levels as we move into March - June could change the math here.11:53
BrainstormUpdates for Vanuatu: +3 cases since 2 days ago12:09
BrainstormNew from ECDC: Data on country response measures to COVID-19: This downloadable data file contains information on non-pharmaceutical interventions (or response measures)  that countries in the EU/EEA have reported to date. → https://www.ecdc.europa.eu/en/publications-data/download-data-response-measures-covid-1912:23
BrainstormNew from The Atlantic: We Might Not Need Annual COVID Shots: Last June, as the Delta variant sat poised to take the globe by storm, Pfizer’s CEO, Albert Bourla, promised the world speed. Should an ultra-mutated version of SARS-CoV-2 sprout, he said , his company could have a [... want %more?] → https://www.theatlantic.com/science/archive/2022/02/covid-vaccine-new-variants/622903/13:21
BrainstormNew from r/COVID19: COVID19: CDC says waiting longer between Pfizer, Moderna doses may reduce rare myocarditis risk for younger men → https://www.reddit.com/r/COVID19/comments/t09xmc/cdc_says_waiting_longer_between_pfizer_moderna/13:41
BrainstormNew from COVID on Twitter: Dr Emma Hodcroft (@firefoxx66): "Everyone should be involved in research. We've seen in this pandemic that all research matters - all research counts. But we need to democratize how research is done. We need to transfer the ability to do research to everyone." @DrMikeRyan @WHO → https://twitter.com/firefoxx66/status/149682754761068135013:51
BrainstormUpdates for Germany: +225524 cases since 23 hours ago15:04
BrainstormNew from r/Coronavirus: Coronavirus: Moderna expects at least $19 billion in Covid vaccine sales in 2022, reports big fourth-quarter earnings beat → https://old.reddit.com/r/Coronavirus/comments/t0adgt/moderna_expects_at_least_19_billion_in_covid/15:10
BrainstormNew from StatNews: Pharma: STAT+: Pharmalittle: Drugmakers push back against Medicare on Alzheimer’s drug; South Africa says Merck Covid pill isn’t cost-effective → https://www.statnews.com/pharmalot/2022/02/24/covid19-vaccine-merck-pfizer-biogen-alzheimers-jnj-africa/15:40
BrainstormNew from COVID on Twitter: John Burn-Murdoch (@jburnmurdoch): And a reminder:As with the Covid pandemic, the @FT is making the best of our coverage of the Russian invasion free to read, and will be adding one new free piece every day twitter.com/jburnmurdoch/s… → https://twitter.com/jburnmurdoch/status/149685970554474905716:01
BrainstormUpdates for Hong Kong: +8798 cases, +40 deaths since 14 hours ago16:06
BrainstormNew from COVID on Twitter: Tulio de Oliveira (@Tuliodna): Genomics and spatial epidemiology to guide HIV-1 response in hot-spots in South Africa. It is exciting to see how similar techniques used for COVID-19 genomics surveillance can help other big epidemics in Africa. Open Access publication out today! @ftanser [... want %more?] → https://twitter.com/Tuliodna/status/149686331390441882816:11
BrainstormNew from COVID on Twitter: Theo Sanderson (@theosanderson): Updated rise and fall of SARS-CoV-2 lineages in England(aware that much more important things are afoot) pic.twitter.com/E8VZICGaTp → https://twitter.com/theosanderson/status/149687312925945446516:51
xxI survived 2 years of a deadly pandemic. Guess what my reward is.16:55
xxin other news, nobody wearing masks, nobody keeping physical distance, nobody desinfecting hands, nobody checking vaccination status, ...16:56
BrainstormUpdates for Germany: +200151 cases, +276 deaths since 23 hours ago — Canada: +3921 cases, +58 deaths since 22 hours ago17:09
BrainstormNew from r/COVID19: COVID19: Medicago and GSK announce the approval by Health Canada of COVIFENZ®, an Adjuvanted Plant-Based COVID-19 Vaccine → https://www.reddit.com/r/COVID19/comments/t0ejsz/medicago_and_gsk_announce_the_approval_by_health/17:20
_naanxx, where is that17:34
xx_naan: the whole area of moldova/ukraine17:34
xxthough there are conflicting reports of a curfew being in effect where I am now17:34
xxpeople are still out17:35
BrainstormNew from ClinicalTrials.gov: (news): Immunogenicity and Safety Study of the 3rd Booster Dose Using the High or Medium Dose of Inactivated Vaccine in Healthy Adults in in Hong Kong → https://clinicaltrials.gov/ct2/show/NCT0525423617:42
BrainstormNew from ClinicalTrials.gov: (news): Reparixin as add-on Therapy to Standard of Care to Limit Disease Progression in Adult Patients With COVID-19. → https://clinicaltrials.gov/ct2/show/NCT0525499017:52
BrainstormNew from ClinicalTrials.gov: (news): Post Vaccination Adverse Events in Covid-19 Vaccine Recipients → https://clinicaltrials.gov/ct2/show/NCT0525497718:02
BrainstormNew from ClinicalTrials.gov: (news): Nutrition and LOComotoric Rehabilitation in Long COVID-19 → https://clinicaltrials.gov/ct2/show/NCT0525430118:11
BrainstormNew from ScienceNews: The COVID-19 pandemic is not an on-off switch: The pandemic is more of a dimmer switch, and it will be a slow slide to the endemic phase, says epidemiologist Aubree Gordon. → https://www.sciencenews.org/article/covid-pandemic-endemic-variant-dimmer-switch18:30
BrainstormNew from COVID on Twitter: Scott Gottlieb, MD (@ScottGottliebMD): Critics must distinguish between conservative commentators who supported development, distribution, uptake of #Covid vaccines -- but opposed government mandates; and those who were anti-vax. @BenShapiro is NOT anti-vax. He regularly encouraged [... want %more?] → https://twitter.com/ScottGottliebMD/status/149690665403778253018:59
BrainstormUpdates for Italy: +47493 cases, +249 deaths since 23 hours ago19:01
BrainstormNew from Contagion Live: CDC Updates COVID-19 Vaccine Timeline to Reduce Myocarditis Risk: CDC expands recommended timeline between second and third COVID-19 vaccine to 8 weeks for people 12 years and older, especially for young men, to reduce the risk of myocarditis. → https://www.contagionlive.com/view/cdc-updates-covid-19-vaccine-timeline-to-reduce-myocarditis-risk19:09
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): A holistic assessment of why the efficacy of vaccines varies extensively between people (e.g.antibody titers 2-3 orders of magnitude), and how targeting the innate immune system can help us get a universal β-coronavirus [... want %more?] → https://twitter.com/EricTopol/status/149691862626319156419:49
BrainstormNew from BioNTech: Pfizer and BioNTech Receive Positive CHMP Opinion for COVID-19 Vaccine Booster in Adolescents 12 through 17 Years of Age in the European Union: NEW YORK AND MAINZ, GERMANY, February 24, 2022 — Pfizer Inc.  (NYSE: PFE, [... want %more?] → https://investors.biontech.de/news-releases/news-release-details/pfizer-and-biontech-receive-positive-chmp-opinion-covid-1920:00
BrainstormUpdates for United Kingdom: +39782 cases, +126 deaths since 23 hours ago20:06
BrainstormNew from NPR Science: Looks like non-mRNA vaccines can be as good as Pfizer and Moderna in certain scenarios: The consensus has been that Pfizer and Moderna are most protective. But a study looking at 5 vaccines — including [... want %more?] → https://www.npr.org/sections/goatsandsoda/2022/02/24/1082529219/looks-like-non-mrna-vaccines-can-be-as-good-as-pfizer-and-moderna-in-certain-sce20:10
BrainstormNew from Contagion Live: With Two Firsts, Health Canada Approves Covifenz COVID-19 Vaccine: This is the first authorized COVID-19 vaccine that was developed by a Canadian-based company, and the first that used a plant-based protein technology. → https://www.contagionlive.com/view/with-two-firsts-health-canada-approves-covifenz-covid-19-vaccine20:51
BrainstormUpdates for Spain: +35892 cases, +220 deaths since 23 hours ago21:06
BrainstormNew from CIDRAP: COVID-19 Scan for Feb 24, 2022: SARS-CoV-2 antibodies in South Africa COVID rapid antigen test reliability → https://www.cidrap.umn.edu/news-perspective/2022/02/covid-19-scan-feb-24-202221:40
BrainstormUpdates for France: +68877 cases, +282 deaths since 23 hours ago22:00
BrainstormNew from Contagion Live: What’s New With Non–COVID-19 Vaccines: Although COVID-19 vaccination remains the primary focus for health care,other paramount vaccines need to be recognized. Here is a review. → https://www.contagionlive.com/view/what-s-new-with-non-covid-19-vaccines22:10
BrainstormNew from CIDRAP: Patients, pharma execs express low trust in drug supply chains: Mary Van Beusekom | News Writer | CIDRAP News Feb 24, 2022 Fully 40% of patients who rely on prescription drugs suspect that supply chain disruptions will put them at risk. → https://www.cidrap.umn.edu/news-perspective/2022/02/patients-pharma-execs-express-low-trust-drug-supply-chains22:20
BrainstormNew from CIDRAP: COVID-19 in pregnancy tied to poor birth outcomes: Stephanie Soucheray | News Reporter | CIDRAP News Feb 24, 2022 Severe COVID in moms was linked to pre-labor C-section, preterm birth, stillborn birth, and infant intensive care. → https://www.cidrap.umn.edu/news-perspective/2022/02/covid-19-pregnancy-tied-poor-birth-outcomes22:40
BrainstormNew from CIDRAP: US officials plan for next pandemic phase as vaccine uptake drops globally: Lisa Schnirring | News Editor | CIDRAP News Feb 24, 2022 Efforts are under way to overhaul the nation's COVID-19 strategy. → https://www.cidrap.umn.edu/news-perspective/2022/02/us-officials-plan-next-pandemic-phase-vaccine-uptake-drops-globally23:09

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