libera/##covid-19/ Saturday, 2022-02-26

BrainstormNew from r/COVID19: COVID19: Recurrent SARS-CoV-2 RNA Detection after COVID-19 Illness Onset during Pregnancy → https://old.reddit.com/r/COVID19/comments/t1iay9/recurrent_sarscov2_rna_detection_after_covid19/00:57
BrainstormUpdates for Hong Kong: +10010 cases, +72 deaths since a day ago — Tonga: +66 cases since a day ago01:05
BrainstormNew from r/COVID19: COVID19: CDC Media Telebriefing: Update on COVID-19 → https://old.reddit.com/r/COVID19/comments/t1id2z/cdc_media_telebriefing_update_on_covid19/01:06
BrainstormNew from r/COVID19: COVID19: Remote Patient Monitoring During COVID-19 An Unexpected Patient Safety Benefit → https://old.reddit.com/r/COVID19/comments/t1ijnu/remote_patient_monitoring_during_covid19_an/01:15
BrainstormNew from BBC Health: Covid: Five things we still need to keep an eye on: The UK is moving to its "living with Covid" phase, but the virus still needs to be watched closely. → https://www.bbc.co.uk/news/health-6049415902:03
BrainstormUpdates for Canada: +6718 cases, +86 deaths, +50541 tests (1.5% positive) since 10 hours ago02:07
BrainstormNew from COVID on Twitter: Dr. Jorge A. Caballero stands with  (@DataDrivenMD): Prof. Iwasaki’s work has informed our understanding of everything from #COVID19 during pregnancy to #LongCOVID. This honor is well-deserved, and she’s a must-follow (IMHO) twitter.com/virusesimmunit… → https://twitter.com/DataDrivenMD/status/149737723220068761602:13
BrainstormNew from r/COVID19: COVID19: Presence of Symptoms 6 Weeks After COVID-19 Among Vaccinated and Unvaccinated U.S. Healthcare Personnel → https://old.reddit.com/r/COVID19/comments/t1lo4p/presence_of_symptoms_6_weeks_after_covid19_among/03:49
BrainstormNew from COVID on Twitter: Justin Lessler (@JustinLessler): The new @CDCgov #covid19 risk levels and guidance seems immensely reasonable. One might quibble about the specific numbers, but the approach focuses on the important indicators and is flexible to changing severity. (1/2) cdc.gov/coronavirus/20… → https://twitter.com/JustinLessler/status/149740244409513574403:58
BrainstormUpdates for South Korea: +166206 cases, +112 deaths since 23 hours ago — New Zealand: +13623 cases, +31015 tests (43.9% positive) since 22 hours ago — Tonga: +1 deaths since 2 hours ago04:00
BrainstormNew from COVID on Twitter: Scott Gottlieb, MD (@ScottGottliebMD): New analysis from #CDC confirms high attack rate of Omicron in households, but spread was substantially lower where household contacts of index patients received a COVID-19 booster dose, or where index patient was fully vaccinated within previous [... want %more?] → https://twitter.com/ScottGottliebMD/status/149741702141532570004:53
BrainstormUpdates for United Kingdom: +399 cases since 8 hours ago05:02
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): The US Omicron wave is receding but the number of Americans reported dying each day is still horrifyingThis weekFeb 223415Feb 23    2911Feb 24    2877Feb 25    2733newsnodes.com/us → https://twitter.com/EricTopol/status/149742382387175835205:12
TuvixWow, from the MMWR today about Omicron transmission in households, there's a notable difference comparing those "who ever work a mask at home [while infectious]" vs. those "who never work a mask at home" (40% vs 69%)05:58
TuvixYet another example where even good-effort masking makes a difference, and this in a setting where airflow is typically very poor.05:58
TuvixThe bot had the article reference above, but this MMWR: https://www.cdc.gov/mmwr/volumes/71/wr/mm7109e1.htm?s_cid=mm7109e1_w05:59
BrainstormUpdates for Germany: +167488 cases since 22 hours ago06:07
TuvixI wonder a bit if this already promissing report on mitigations measures like best-effort isolation & masking is possibly an understatement of the benefit of personal mitigation; a high showing of enrollment households either never replied to the initial contact or declined to participate.06:08
* Tuvix has the feeling those ignoring the outreach or declining were perhaps less likely to follow mitigations. Anecdotally, this lines up with my own experiences where places that ignored or pushed back on data or testing usually weren't intertested in doing even locally-required mitigations :\06:10
BrainstormNew from This Week In Virology: TWiV 870: COVID-19 clinical update #103 with Dr. Daniel Griffin: In COVID-19 clinical update #102, Daniel Griffin covers immunocompromised people, hospitalization of children, vaccine usage update, Omicron and cross-reactive neutralizing antibodies, reinfection prevents disease in hamsters, repeated [... want %more?] → https://www.microbe.tv/twiv/twiv-870/06:19
TuvixThe correlation is a bit lower, but that same study also finds more risk reduction from partial-masking with a positive household contact as compared to those with just prior infection.06:22
TuvixThis makes some sense inherntly of course, since prior protection is well understood not to confirm decent protection against reinfection, but it's interesting to see the relative risk reduction stacked up by something as simple as a mask.06:23
Tuvixnot to confer*06:24
BrainstormNew from Science-Based Medicine: I Won’t Stop Talking About COVID Until You Stop Talking About COVID: What better way is there for me to convey to others that they should stop talking about COVID than for me to talk about it constantly? The post  first appeared on Science-Based Medicine . → https://sciencebasedmedicine.org/stop-talking/06:38
BrainstormNew from r/COVID19: COVID19: First evidence of a highly divergent lineage of SARS-CoV-2 in white-tailed deer and of deer-to-human transmission. → https://old.reddit.com/r/COVID19/comments/t1p8ui/first_evidence_of_a_highly_divergent_lineage_of/06:57
BrainstormUpdates for Selangor, Malaysia: +7290 cases, +5 deaths since 23 hours ago — Novosibirsk, Russia: +4796 cases, +13 deaths since 23 hours ago — Maule, Chile: +3709 cases, +5 deaths since 23 hours ago — Kedah, Malaysia: +2621 cases, +5 deaths since 23 hours ago07:00
BrainstormNew from r/Coronavirus: Daily Discussion Thread | February 26, 2022: Please refer to our Wiki for more information on COVID-19 and our sub. You can find answers to frequently asked questions in our FAQ , where there is valuable information such as our: → https://old.reddit.com/r/Coronavirus/comments/t1rptk/daily_discussion_thread_february_26_2022/09:09
BrainstormUpdates for Brunei: +3969 cases since 23 hours ago13:03
BrainstormNew from Reddit (test): CoronaVirus_2019_nCoV: Is Omicron subvariant BA.2 disarming key antibody treatment? What we know so far: “We’re just drawing attention to the fact that BA.2 is quite resistant to sotrovimab in the lab, and that raises questions about [... want %more?] → https://old.reddit.com/r/CoronaVirus_2019_nCoV/comments/t1w9wx/is_omicron_subvariant_ba2_disarming_key_antibody/13:53
BrainstormNew from Reddit (test): nCoV: Global COVID Cases For 26FEB22 → https://old.reddit.com/r/nCoV/comments/t1wi7w/global_covid_cases_for_26feb22/14:02
BrainstormUpdates for Germany: +168438 cases since 23 hours ago14:05
BrainstormNew from Reddit (test): Covid2019: FDA authorizes revisions to Evusheld dosing → https://old.reddit.com/r/Covid2019/comments/t1wq9r/fda_authorizes_revisions_to_evusheld_dosing/14:12
BrainstormNew from COVID on Twitter: Marc Veldhoen (@Marc_Veld): For a better understanding of why older people are more vulnerable. One part is reducing your own immune capability with antibodies to innate factors.Why do people die from COVID-19?science.org/doi/10.1126/sc… → https://twitter.com/Marc_Veld/status/149756122196432077214:22
BrainstormNew from COVID on Twitter: Scott Gottlieb, MD (@ScottGottliebMD): It’s established that animal reservoirs of SARS-CoV-2 can lead to viral mutations and spillback from wildlife to humans. These findings represent first evidence of a highly divergent strain of Covid in white-tailed deer that subsequently [... want %more?] → https://twitter.com/ScottGottliebMD/status/149759666541017497716:46
TuvixWhy do professionals get on national programs and say things that are so easily proven false? This time it was a doctor justifying the CDC's mask changing guidance citing the "low" risk and specifically included deaths in that figure. Deaths in the US are currently a bit flat around the point of the Delta peak.16:50
TuvixSo on one hand this doctors says that summer was good but we "let down our guard" (my paraphrasing his assessment, which I mostly agree with up to this point) and in doing so caused more harm during Delta than if we had mitigations.16:51
TuvixBut on the other hand, he can't review the numbers he's using to justify what he called a low rate of death which is, using the 7-day rolling avearge now vs. Delta, 89% of the Delta peak.16:52
Tuvix89% is not a "small" number.16:53
xxTuvix: because they are not professionals, they are just people with a title16:55
xxunless you mean 'professional' as in 'they are employed in a field'16:56
TuvixMD means quite a bit more than that.16:56
xxi.e. anyone is a professional cleaner if they get hired to clean something16:56
xxTuvix: we've all seen MDs that are dumb16:56
TuvixYou need a Medical Degree and to pass the bar exam to clean?16:56
TuvixYes, and we've seen presidents dumb enough to doctor a chart with a sharpie on national TV too.16:56
xxheh16:56
TuvixBoth are irresponsible.16:56
TuvixIf your point is 'some people are bad at thier jobs' sure, but it's reductive to the point I was making.16:57
TuvixAnd really, shame on the news network for not verifying the facts their guest was presenting (this was from a TV network that usually tries to do that) but of course you can't vet every reply a guest will provide on a live interview, so I'm not really that critical of the network in this case.16:58
TuvixIt's just misleading. The question over how to deal with restrictions in the US usefully *is* an important topic, but to hide it behind a claim that our *current* death rate is "low" is really ignoring the fact that it's not, and has been worse than all of our peer nations.16:58
BrainstormUpdates for Canada: +7779 cases, +99 deaths since 23 hours ago17:00
xxthe news are probably not caring about covid as much anymore17:00
TuvixThe death in the US this week also got slightly "stuck" and is no longer declining (in fact it's going up slightly.) Hopefully that's just the impact of the more widely undervaccinated more rural & southern parts of the country and not a trend, but we saw Delta's recovery get stuck and not improve until Omicron made it worse.17:01
TuvixThey didn't care so they brought an expert on to talk about it?17:01
TuvixPerhaps the better comparison is against last winter's peak (ie: Alpha) in the US, since that was pre-vaccine but also a prior VoC. By that metric the US is, today, at a death rate of 56%, but some states are performing much worse. Alabama at 89%, Georgia at 73%, Mississippi at 82% (after peaking at 200% early Feb 2022.)17:08
TuvixThis NYT interactive page is pretty neat here actually; it's got a section on how cases/hospitalizations/deaths are trending, broken down by states: https://www.nytimes.com/interactive/2021/us/covid-cases.html17:10
xxthey probably had the expert scheduled from before17:13
BrainstormNew from Reddit (test): CoronavirusUK: REMINDER: No Covid Dashboard Update at Weekends → https://old.reddit.com/r/CoronavirusUK/comments/t20dxm/reminder_no_covid_dashboard_update_at_weekends/17:15
TuvixSure, it's the nonsensical claim that death rates are low in the US. That's selectively mostly-true if you cherry-pick states, but it's certainly not reflective of the country as a whole at the moment, and downright wrong in the worse-performing states.17:15
TuvixAs I said above, the segment on the broadcast was limited and I don't really blame the network, but it's such an obvious fact not to be ready to talk about. Weekend anchors aren't always the quickest on the draw either for common news programms though.17:19
TuvixReal nice hospital admit chart by age at that same link too, this page is quite nifty. By hospital admission, the 30-49 year old group was 5.3x less likely to be hospitalized vs. the 70+ group at the peak of Omicron.17:23
TuvixThat's actually less of a reduction than I would have expected, but this is also combining all vaccination status.17:24
Tuvixie: some of the reason the younger group is as high as it is is because more of them aren't vaccinated, thus the rate of hospitalization is impacted by that in addition to the benefits of being less effected by advanced age.17:24
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol):  from @ONS Booster reduction of death for Omicron and Delta across all age groupsmedrxiv.org/content/10.110… as compared with 2-doses, unvaccinatedby @IsobelLWard @Vnafilyan and colleagues pic.twitter.com/PxLA0ZAIdH → https://twitter.com/EricTopol/status/149761413782367436817:53
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): To clarify, these are hazard ratios for death for Omicron *vs* Delta"The reduction in risk of death involving COVID-19 was also most pronounced in individuals who had received a booster" → https://twitter.com/EricTopol/status/149761755921386291418:12
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): "Regardless of age, reduction of the risk of death from Omicron relative to Delta more was more pronounced in people who had received a booster than in those having received only two doses" → https://twitter.com/EricTopol/status/149762233658064486518:22
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): More on this today from a large Qatar studymedrxiv.org/content/10.110…"Effectiveness of BA.1 infection against reinfection with BA.2 was estimated at 94.9%" pic.twitter.com/SRNtYp690N → https://twitter.com/EricTopol/status/149762822412104499218:50
BrainstormNew from Reddit (test): China_Flu: Respiratory dysfunction three months after severe COVID-19 is associated with gut microbiota alterations → https://old.reddit.com/r/China_Flu/comments/t22qg6/respiratory_dysfunction_three_months_after_severe/19:09
BrainstormNew from COVID on Twitter: Marc Veldhoen (@Marc_Veld): Covid: Five things we still need to keep an eye on bbc.com/news/health-60… → https://twitter.com/Marc_Veld/status/149763847446329754119:28
BrainstormNew from COVID on Twitter: Marc Veldhoen (@Marc_Veld): Geographical clustering of the earliest known COVID-19 cases and the proximity of positive environmental samples to live-animal vendors suggest that the Huanan Seafood Wholesale Market in Wuhan was the site of origin of the COVID-19 pandemic. → https://twitter.com/Marc_Veld/status/149764018009378816219:38
BrainstormUpdates for Italy: +39360 cases, +210 deaths, +434077 tests (9.1% positive) since a day ago19:59
BrainstormNew from r/COVID19: COVID19: SARS-CoV-2 emergence very likely resulted from at least two zoonotic events → https://old.reddit.com/r/COVID19/comments/t264r7/sarscov2_emergence_very_likely_resulted_from_at/21:23
BrainstormNew from COVID on Twitter: Bill Hanage (@BillHanage): It is fair to say that the pandemic has not been handled well. But can we get a sense of how much worse it could have been? Yes we can, at least roughly, by comparing per-capita mortality in different places to date. The results are quite striking 1/n → https://twitter.com/BillHanage/status/149767177280363315421:42
BrainstormUpdates for France: +53623 cases, +101 deaths since 23 hours ago — Germany: +240 deaths since 23 hours ago22:05
BrainstormNew from COVID on Twitter: Marc Veldhoen (@Marc_Veld): Highly divergent white-tailed deer SARS-CoV-2 with potential deer-to-human transmissionA highly different evolutionary path of SARS-COV-2.biorxiv.org/content/10.110… → https://twitter.com/Marc_Veld/status/149768265551680307322:30
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): Good summary @nature  nature.com/articles/d4158…by @saimamaysidik These findings highlight how impressive/smart our immune response is, since BA.1 and BA.2 are so different, so far apart as antigens pic.twitter.com/zgWMymR3Fg → https://twitter.com/EricTopol/status/149769086189891993922:59
BrainstormUpdates for Canada: +4184 cases, +59 deaths since 21 hours ago23:08
BrainstormNew from COVID on Twitter: Scott Gottlieb, MD (@ScottGottliebMD): Important perspective from @K_G_Andersen on the earlier pre-print documenting divergent zoonotic evolution — and then subsequent reintroduction — of a heavily mutated strain of SARS-CoV-2 into a human host. Identifies key future implications, [... want %more?] → https://twitter.com/ScottGottliebMD/status/149769711072814284823:28

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