libera/##covid-19/ Saturday, 2022-03-05

BrainstormNew from COVID on Twitter: Michael Lin, MD PhD  (@michaelzlin): Not surprised that FDA rejected the inactivated vaccine Covaxin (produced by Bharat, marketed by Ocugen) for 2-18yo. Bharat-Ocugen presented data that their vaccine produced higher antibody levels than adults, and applied for EUA based on [... want %more?] → https://twitter.com/michaelzlin/status/149988489747269632100:17
BrainstormNew from COVID on Twitter: Michael Lin, MD PhD  (@michaelzlin): The effect of having those antibodies ahead of time may be marginal on top of what the children's bodies are doing already. It won't hurt, but FDA requires knowledge of what the VE is, not just anything >0%. → https://twitter.com/michaelzlin/status/149988804957597696100:26
BrainstormNew from COVID on Twitter: Michael Lin, MD PhD  (@michaelzlin): Actually I checked myself. You can see Pfizer's 3ug dose chosen for 2-5yo produced more nAbs than the approved dose for 16-25yo, which we know had VE>50% pre-Omicron. But this 3ug was not sufficient in kids (although not clear if FDA is using Omicron [... want %more?] → https://twitter.com/michaelzlin/status/149989088630548480000:36
BrainstormNew from COVID on Twitter: Marc Veldhoen (@Marc_Veld): Effects of BA.1/BA.2 subvariant, vaccination, and prior infection on infectiousness of SARS-CoV-2 Omicron infectionsBA.2 appears substantially more infectious than BA.1 subvariant. This may reflect higher viral load and/or longer duration of infection, [... want %more?] → https://twitter.com/Marc_Veld/status/149989214680718541500:46
BrainstormNew from COVID on Twitter: Marc Veldhoen (@Marc_Veld): It now contains the recommendation to use mulnuparavir, only for non-severe COVID-19 patients with the highest risk of hospitalization.who.int/news/item/03-0… → https://twitter.com/Marc_Veld/status/149989509166157414700:56
BrainstormUpdates for Vietnam: +173631 cases, +97 deaths since 21 hours ago — Hong Kong: +52523 cases, +188 deaths since 23 hours ago — Malaysia: +33209 cases, +78 deaths since a day ago — Cook Is.: +11 cases, +134 tests (8.2% positive) since 23 hours ago01:09
BrainstormUpdates for Slovakia: +13483 cases since 23 hours ago02:05
TuvixCDC update for today puts the 7-day rolling daily average of death in the US at just a bit over the entier-pandemic average. Another couple days of this pace of downtrend and we'll finally be moving the average lower, not higher as we have been for several months now.02:17
qkall[m]finally some good news... before the parachute spiders hit02:19
TuvixWell, to a point; pandemic average is 1300 dying daily, which is still pretty awful.02:20
TuvixWe need to be doing a lot better than average, but the more distrubing trend is that post-vaccine availability the average loss of live hasn't changed all that much, it's just shifted more of that toll to the unvaccinated a bit more.02:21
qkall[m]duly noted02:22
TuvixPandemic average is 13.2 times the annual loss of life of influenza, which means the US is still exceeding that by a bit yet, at a rolling-weekly-average of 14.3x02:22
LjLTuvix, pwr22: <Brainstorm> New from r/Science: science: National narcissism identified as a robust predictor of belief in COVID-19 conspiracy theories → https://old.reddit.com/r/science/comments/t6ytop/national_narcissism_identified_as_a_robust/03:17
pwr22Ha ha, "national narcissism", never heard that one before 😀03:18
LjLit's American exceptionalism except under a more psych-sounding name03:19
BrainstormNew from r/Science: science: National narcissism identified as a robust predictor of belief in COVID-19 conspiracy theories → https://old.reddit.com/r/science/comments/t6ytop/national_narcissism_identified_as_a_robust/03:19
BrainstormUpdates for South Korea: +254326 cases, +216 deaths since 23 hours ago — New Zealand: +18880 cases, +14051 tests (134.4% positive) since 22 hours ago04:04
BrainstormNew from r/Coronavirus: Coronavirus: A deer may have passed COVID-19 to a person, study suggests → https://old.reddit.com/r/Coronavirus/comments/t6zixp/a_deer_may_have_passed_covid19_to_a_person_study/05:34
BrainstormNew from r/Coronavirus: Coronavirus: ‘Unprecedented Amounts Of Children With Anxiety’: Younger Generation Stressed While Living With COVID → https://old.reddit.com/r/Coronavirus/comments/t716m1/unprecedented_amounts_of_children_with_anxiety/05:53
BrainstormUpdates for Germany: +180881 cases since 14 hours ago — United Kingdom: +406 cases since 9 hours ago06:03
BrainstormUpdates for China: +52804 cases since 23 hours ago — Selangor, Malaysia: +8897 cases, +10 deaths since 23 hours ago — W.P. Kuala Lumpur, Malaysia: +4105 cases, +2 deaths since 23 hours ago — Bashkortostan, Russia: +3297 cases, +12 deaths since 23 hours ago07:05
BrainstormNew from Reddit (test): CoronaVirus_2019_nCoV: Pro-Putin Disinformation on Ukraine Is Thriving in Online Anti-Vax Groups → https://old.reddit.com/r/CoronaVirus_2019_nCoV/comments/t72o6n/proputin_disinformation_on_ukraine_is_thriving_in/07:46
BrainstormNew from MedicineNet: (news): Vets Spot the Delta Variant in a House Cat → http://www.medicinenet.com/script/main/art.asp08:42
BrainstormNew from r/Coronavirus: Daily Discussion Thread | March 05, 2022: Please refer to our Wiki for more information on COVID-19 and our sub. You can find answers to frequently asked questions in our FAQ , where there is valuable information such as our: → https://old.reddit.com/r/Coronavirus/comments/t74ojg/daily_discussion_thread_march_05_2022/09:10
BrainstormNew from COVID on Twitter: Tulio de Oliveira (@Tuliodna): Very good piece and we will make sure in South Africa that we help our continent to challenge this status quo! We did with science and will work hard to avoid COVID to become endemic of the global south. twitter.com/paimadhu/statu… → https://twitter.com/Tuliodna/status/150003000784605594009:58
BrainstormNew from Reddit (test): China_Flu: Special Authorities for Dealing with the New Corona Virus Law (Temporary Order), 2020 → https://old.reddit.com/r/China_Flu/comments/t775q0/special_authorities_for_dealing_with_the_new/12:10
-Bridgestorm- 🏠 Gempa bumi! Lindu! Earthquake! 5.9 M tremor, registered by InfoHumasBMKG,infoBMKG, occurred 5 minutes ago (12:02:39 UTC), during twilight, Off W Coast Of Northern Sumatra (4.56, 94.84), ↓17 km likely felt 250 km away (in Banda Aceh, Sabang…) by 266800 people → https://twitter.com/infoBMKG/status/1500080348197048323 https://twitter.com/InfoHumasBMKG/status/1500080689663803394 (Twitter)13:08
BrainstormNew from COVID on Twitter: John Burn-Murdoch (@jburnmurdoch): This is a trend I first really noticed with Covid, but the amount of hyperbolic, alarmist nonsense being spread by Americans about the situation in Europe is mindblowing.Perhaps this is true for a few dozen people, but it's absurd to frame it as "what [... want %more?] → https://twitter.com/jburnmurdoch/status/150008085714670387813:16
BrainstormNew from r/COVID19: COVID19: Immunogenicity of an Ad26-based SARS-CoV-2 Omicron Vaccine in Naïve Mice and SARS-CoV-2 Spike Pre-immune Hamsters → https://old.reddit.com/r/COVID19/comments/t78f7j/immunogenicity_of_an_ad26based_sarscov2_omicron/13:35
BrainstormNew from Reddit (test): nCoV: Global COVID Cases For 05MAR22 → https://old.reddit.com/r/nCoV/comments/t78pf7/global_covid_cases_for_05mar22/13:53
BrainstormNew from This Week In Virology: TWiV 872: COVID-19 clinical update #104 with Dr. Daniel Griffin: In COVID-19 clinical update #104, Daniel Griffin reviews effectiveness of mRNA vaccines among children, number of children affected by disease, accuracy of rapid antigen tests, CDC guidance for prevention strategies, monoclonal antibody [... want %more?] → https://www.microbe.tv/twiv/twiv-872/14:42
BrainstormUpdates for Germany: +186111 cases since 23 hours ago15:01
BrainstormNew from Reddit (test): CoronavirusUK: Covid pandemic sparks steep rise in number of people in UK with long-term illness → https://old.reddit.com/r/CoronavirusUK/comments/t79owo/covid_pandemic_sparks_steep_rise_in_number_of/15:11
ublxapparently this preprint ( https://www.medrxiv.org/content/10.1101/2022.02.27.22271328v1.full ) provoked this tweet response: https://twitter.com/_mbdr_/status/149980855169858765115:49
ublxhowever one commenter objected to SSI's framing, saying: Perhaps best not to broadcast this to a public not trained in analysis of data. Perhaps you should have led with this (from your own report) "SSI understreger dog, at beregningerne er behæftet med betydelig usikkerhed." (SSI emphasizes, however, that the calculations are subject to considerable uncertainty)15:50
ublxthe commenter further remarked: @SSI_dk doesn't have a lot of credibility left in their public statements.15:50
BrainstormUpdates for Hong Kong: +37529 cases, +220 deaths since 14 hours ago16:03
BrainstormNew from COVID on Twitter: Marc Veldhoen (@Marc_Veld): For the handful of places around the world that effectively stopped COVID-19 transmission, vaccine complacency has become an unintended side effect of their success.‘COVID zero’ regions struggle with vaccine complacencynature.com/articles/d4158… → https://twitter.com/Marc_Veld/status/150013598812276327016:56
BrainstormNew from r/Coronavirus: Coronavirus: Striking new evidence points to Wuhan seafood market as the pandemic's origin point → https://old.reddit.com/r/Coronavirus/comments/t7cgpr/striking_new_evidence_points_to_wuhan_seafood/17:54
BrainstormUpdates for Canada: +7733 cases, +47 deaths since 21 hours ago18:02
BrainstormNew from r/COVID19: COVID19: Do three new studies add up to proof of COVID-19’s origin in a Wuhan animal market? → https://old.reddit.com/r/COVID19/comments/t7e8fm/do_three_new_studies_add_up_to_proof_of_covid19s/18:32
LjLublx: I'm not myself trained in data analysis but the CIs in that abstract are if anything considerably narrow compared to what I've become used to seeing. So what's the uncertainty? I'd say however I can't see how "18% of 🇩🇰 will have long covid 6+ months later w/those numbers" automatically follows18:49
LjLMainly because do we know how the vaccine affects these numbers, and do we know what they are with specifically Omicron18:50
ublxthe dissenter in the comment thread indicated they would comment in more detail "later"18:52
LjLCertainly not from this study which is from data way way pre omicron and never mentions omicron18:52
ublxbut i dropped the links here partly by way bookmark, while moving on to other reading18:52
BrainstormNew from Contagion Live: Social Determinants of Health and COVID-19 Mortality: Associations between social determinants of health (SDOH) and COVID-19 mortality varied across racial and ethnic groups and community types. → https://www.contagionlive.com/view/social-determinants-of-health-and-covid-19-mortality18:52
ublxother remarks i noted in passing: yes, not related to omicron; results based on or heavily involving questionnaires; long covid referred to primarily of a lost sense of smell/fatigue nature18:54
ublxi didn't look into any of those caveats myself18:54
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): There is also a major difference in the vaccines used. Hong Kong used a high proportion of Sinovac, which has been shown to be less protective vs Omicron /4 pic.twitter.com/u6Zox0XJn9 → https://twitter.com/EricTopol/status/150016682468346675619:02
BrainstormUpdates for Germany: +162909 cases since 22 hours ago19:05
LjLublx: well if they ignored other aspects of long covid (although it seems to me they covered more than that), it means it's *at least* 30% instead of being 30%. I mean, unless one wants to discount anosmia or fatigue as complaints not important enough to call it long covid, in which case I'd suggest experiencing them19:05
ublxto be clear, the remarks i noted were twitter remarks about the study, not remarks within the study19:16
LjLI know19:20
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): This new report from Hong Kong shows the reduced neutralization and marked waning of CoronaVac compared with a mRNA vaccine vs Omicron thelancet.com/journals/ebiom… @TheLancet  /5 pic.twitter.com/LYVuBllK2X → https://twitter.com/EricTopol/status/150017187557337497719:20
BrainstormNew from COVID on Twitter: Marc Veldhoen (@Marc_Veld): "covid-19 was associated with more severe maternal infection and worse pregnancy outcomes than during the wildtype dominance period. Most women admitted with SARS-CoV-2 related symptoms were unvaccinated. " → https://twitter.com/Marc_Veld/status/150017639603911885719:39
BrainstormUpdates for Italy: +41364 cases, +173 deaths, +381484 tests (10.8% positive) since a day ago20:01
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): The UK and many European countries have now reached 3-dose vaccination rates of >90% for people 65+  assets.publishing.service.gov.uk/government/upl…But the US is at 66% for boosters among this high risk age group /7 pic.twitter.com/1dglxj5jpZ → https://twitter.com/EricTopol/status/150018553271368499420:08
BrainstormNew from COVID on Twitter: Helena Kilpinen (@HKilpinen): Really happy to share this new preprint from the group! Wonderful collaboration with @scastesparraka and all credit to @paupuigdevall who, despite the pandemic, put all his skill and ingenuity to this project - see his thread about our findings below. [... want %more?] → https://twitter.com/HKilpinen/status/150019219263532646520:46
BrainstormUpdates for Canada: +5033 cases since 23 hours ago21:10
BrainstormUpdates for Malaysia: +33406 cases, +67 deaths since 20 hours ago22:07
BrainstormNew from r/Coronavirus: (translated) Coronavirus: COVID accumulates in male genital organs, Tulane primate study shows. → https://old.reddit.com/r/Coronavirus/comments/t7hxnv/covid_accumulates_in_male_genital_organs_tulane/22:14
BrainstormUpdates for Vietnam: +173258 cases, +82 deaths since 21 hours ago23:03
BrainstormNew from Reddit (test): CoronaVirus_2019_nCoV: COVID-19 could trigger more disabling strokes: findings also suggest that patients from less wealthy areas may have been at greater risk for serious COVID-19 complications such as stroke because they were less able to [... want %more?] → https://old.reddit.com/r/CoronaVirus_2019_nCoV/comments/t7kd7h/covid19_could_trigger_more_disabling_strokes/23:23
BrainstormNew from Reddit (test): CoronaVirus_2019_nCoV: COVID’s aftershock: Delayed treatments will likely jolt healthcare system for years → https://old.reddit.com/r/CoronaVirus_2019_nCoV/comments/t7ki12/covids_aftershock_delayed_treatments_will_likely/23:33
BrainstormNew from Reddit (test): nCoV: China beefs up military spending, morphs from ‘COVID zero’ to ‘dynamic zero’ | 05MAR22 → https://old.reddit.com/r/nCoV/comments/t7kuif/china_beefs_up_military_spending_morphs_from/23:52

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