| de-facto | whats chest cold? | 00:00 |
|---|---|---|
| de-facto | rpifan, i think its normal to have some side effects, its the immune system reacting to the "evil" intruder, hence its good when it fights the s-protein | 00:10 |
| rpifan | tight chest cough phlegm | 00:16 |
| dTal | is that a normal vaccine reaction? Sounds more like you just coincidentally got sick | 00:17 |
| dTal | maybe you caught a cold from the nurse lol | 00:17 |
| dTal | Jokes aside, sorry to hear you're ill rpifan | 00:18 |
| de-facto | try to drink enough liquid (tea :), its good for both, all bodily functions as well as liquefying phlegm | 00:20 |
| rpifan | dTal, yea i suspect so | 00:23 |
| de-facto | there are even special teas (you can find them in rossmann, dm etc) that are designed for helping with cough "husten und bronchialtee" | 00:27 |
| Brainstorm | New from COVID on Twitter: Bob Wachter (@Bob_Wachter): Covid (@UCSF) Chronicles, Day 327This seems like a benign time, Covid-wise, in the U.S. And it mostly is. But, as usual, it’s actually a pretty confusing time just beneath the surface, with lots of scientific and policy cross-currents. Today, a on the [... want %more?] → https://twitter.com/Bob_Wachter/status/1503510846026227713 | 00:27 |
| dTal | sometimes when I used to feel like shit I'd spike a lemsip with some whiskey | 00:28 |
| dTal | poor old liver would have to take one for the team but damn if you didn't feel a crapton better | 00:28 |
| de-facto | no alcohol no coffee, you remember dTal ? | 00:28 |
| de-facto | its not good for the immune system at the time it should learn how to fight the s-protein | 00:29 |
| dTal | de-facto, for immunity? or gut health? Or any of a number of other reasons? XD | 00:29 |
| dTal | oh right rpifan just got vaxxed | 00:29 |
| dTal | well best stick with the straight lemsip then | 00:29 |
| dTal | it's pretty toxic to mix alcohol and paracetemol anyway | 00:29 |
| de-facto | you found the paper yourself about the dose dependent anticorrelation between antibodies against provocation with an alien protein and caffeine | 00:30 |
| de-facto | (in mice) | 00:30 |
| dTal | yeah I know | 00:30 |
| dTal | regretting it ever since | 00:30 |
| rpifan | well i drink tea | 00:30 |
| rpifan | like black tea | 00:30 |
| dTal | it didn't say nothing about alcohol though | 00:30 |
| rpifan | i do have a nice tea from poland | 00:31 |
| rpifan | for the throat | 00:31 |
| rpifan | its actually pretty nice | 00:31 |
| rpifan | i think ill have another mug | 00:31 |
| de-facto | yeah i did, its causing oxidative stress when its chemically degraded in the body, and immune cells are among the most sensitive against such oxidative stress (hence the benefit from anti-oxidants for the immune system) | 00:31 |
| de-facto | yes (normal amounts) of tea are great (and healthy) | 00:32 |
| Juerd | What causes oxidative stress? Tea?! | 00:34 |
| de-facto | no i think tea contains anti-oxidants | 00:39 |
| Brainstorm | New from COVID on Twitter: Michael Lin, MD PhD (@michaelzlin): One possibility is RNA vax could be S1 biased in terms of antibody induction. Secreted S1 is trimeric so can activate BCR in naive B cells, and being soluble could be more easily processed for presentation on MHC2 to get the 2nd signal from CD4+ T cells. → https://twitter.com/michaelzlin/status/1503519385184395265 | 00:56 |
| Brainstorm | Updates for Hong Kong: +26908 cases, +286 deaths since 23 hours ago — Canada: +3293 cases, +24 deaths since 5 hours ago | 01:06 |
| de-facto | chemically degrading alcohol causes oxidative stress afaik | 01:14 |
| de-facto | or biologically degrading | 01:14 |
| Brainstorm | New from COVID on Twitter: Michael Lin, MD PhD (@michaelzlin): Since full-length S protein was used in both FCS-mutated and FCS-intact protein vaccines in the Krammer study, the superiority of the FCS-mutated protein can't be due to S1-S2 balance. Rather they suggested the protein can just be more stable overall. → https://twitter.com/michaelzlin/status/1503523858145427457 | 01:15 |
| Brainstorm | New from COVID on Twitter: Marc Veldhoen (@Marc_Veld): ‘Stealth’ Omicron Is Stealthy No More: What’s Known About the BA.2 Variantnytimes.com/article/omicro… → https://twitter.com/Marc_Veld/status/1503526118715965451 | 01:24 |
| LjL | https://www-punto--informatico-it.translate.goog/green-pass-addio-a-tappe-calendario/ | 01:27 |
| LjL | The world of school will be interested , as it is preparing to conclude another year marked by closures and distance learning. No more quarantine for anyone who comes into contact with a positive, even in the absence of a vaccine. Then off the FFP2 masks in the classroom, in favor of the surgical ones. | 01:29 |
| LjL | Among the other changes scheduled for April 1st, the dissolution of the Scientific Technical Committee . | 01:29 |
| LjL | it's over! \o/ | 01:29 |
| LjL | meh | 01:29 |
| de-facto | i guess its not meant to be an early April fools joke? | 01:30 |
| LjL | no :\ it's because the state of emergency ends on March 31 | 01:31 |
| LjL | i think dissolving that committee, although maybe that committee has not been super-useful lately, is the thing that unsettles me the most, because | 01:31 |
| LjL | without that, i'd be like "oh well, soon they will see that cases are going back up without a doubt, and they'll have to change course again" | 01:31 |
| LjL | but THAT committee IS the people who are there to tell the government to change course when needed | 01:32 |
| LjL | and it won't exist anymore! | 01:32 |
| de-facto | here the management also is heavily criticized about taking back restrictions while both, infections and hospitalizations are *already* rising | 01:33 |
| de-facto | i mean what is the expectation value of opening up transmission paths? | 01:33 |
| de-facto | i thought that even politicians would understand after observing this for two years | 01:34 |
| de-facto | but politicians hate to have a scientific committee in the background, because it takes away some of their "freedom" of decisions, its much more convenient to decide something and then search experts to support that decisions a-posteriori | 01:36 |
| Brainstorm | New from COVID on Twitter: Michael Lin, MD PhD (@michaelzlin): Would be very informative if @Novavax can test their patients' S1 and S2 antibody responses, and compare to RNA vax recipients. → https://twitter.com/michaelzlin/status/1503531408261742593 | 01:43 |
| Brainstorm | New from COVID on Twitter: Michael Lin, MD PhD (@michaelzlin): Would be very informative if @Novavax can test their patients' S1 and S2 antibody responses, and compare to RNA vax recipients. It can be done in a day and cost a few dollars a sample.An academic lab with sample access could do it too. → https://twitter.com/michaelzlin/status/1503532042960596995 | 01:52 |
| Brainstorm | Updates for Australia: +28647 cases, +13 deaths since 22 hours ago | 02:03 |
| Tuvix | de-facto: Problem is they (the political figures) keep hearing only what they want to. Even the more open scientists admit that we _might_ see spread decline as the combination of more infected and the total level of vaccines improve immune exposure. You & I both know that this is not the only possible future though… | 02:03 |
| Brainstorm | New from COVID on Twitter: Michael Lin, MD PhD (@michaelzlin): Just found this recent study that looked at S1 vs S2 responses. Turns out some people have Abs from earlier coronavirus infections (OC43 and HKU1) that cross-react to SARSCoV2 S2 — that's how conserved it is. RNA vax layers on top a mostly S1 [... want %more?] → https://twitter.com/michaelzlin/status/1503537915955073026 | 02:11 |
| LjL | <Brainstorm> New from Reddit (test): CoronaVirus_2019_nCoV: Hong Kong records highest Omicron death rate in the world | " omicron is not a mild virus it's simply less severe than delta but it's about the same as wuhan → https://old.reddit.com/r/CoronaVirus_2019_nCoV/comments/tebqx5/hong_kong_records_highest_omicron_death_rate_in/ | 02:19 |
| LjL | "What they do in China [he doesn't mean in HK] is that they actually admit people who are infected into an isolation facility whether or not they are sick" | 02:21 |
| LjL | this is not right though | 02:22 |
| LjL | "And remember: these are not boosters, these are the third doses you were always meant to have. Still using the language of boosters makes people think it's take it or leave it... to be up to date with your immunization you need three doses" | 02:23 |
| LjL | were always meant to have?! that's bollocks, that's rewriting history as usual, that just makes me join the people who are wary of what The Experts say | 02:23 |
| LjL | experts: don't say stupid shit | 02:23 |
| dTal | apparently there is a difference between a "booster" and a "third dose" | 02:24 |
| Tuvix | Yup, originally, pre-waning VE (vs. hospitalization & death specifically) the party line at least here in the US was "the boosters are only for the immune-compromised." | 02:24 |
| dTal | to wit, a "third dose" is larger | 02:24 |
| Tuvix | Then of course that all changed when we saw that waning VE was universal, not just something for those with poor immune-response. | 02:24 |
| dTal | I know, it sounds stupid, but that's the NHS party line anyway | 02:24 |
| Tuvix | But, honestly, if you don't know and you're an expert in your field, just bloody say that you don't know and then go on to guess if you (or your interviewer) wish, but make it clear it's a supposition. | 02:25 |
| Tuvix | Some members of that sports-club I'm still avoiding without better improving metrics around me bought into the nonsense really hard back in 2021. He was quite upset when the club briefly re-introduced masks around Delta, stating that he got vaccinated specifically so he wouldn't have to wear one. | 02:27 |
| Tuvix | Of course, it was so unpopular that no one followed the rules anyway, but I wonder how much of that was poor national messaging about the reasons and metrics that drive such decisions. | 02:27 |
| LjL | dTal, the third dose / booster is only larger in the case in the case of Moderna though | 02:28 |
| LjL | with Pfizer and AZ afaik it's the same | 02:28 |
| LjL | so in those cases, is it what, a Schrödinger's thirdooster? | 02:29 |
| de-facto | Tuvix, i just would hope that at some point decisions would get based on empiric data analysis rather than on wishful thinking of incompetent politicians. maybe it needs a few more years for such approaches to get demanded loud enough from a frustrated population about the repeated failures of management | 02:29 |
| Tuvix | Wasn't the moderna dose a half-dose, except for the immune-compromised? Or is this not the usual 3rd / "booster" dose? | 02:29 |
| de-facto | we have seen so far that daily infections increase more and more, even re-infections, so for what reasons (other than wishful thinking) would we assume that this does not continue like that in the future? | 02:30 |
| Brainstorm | New from COVID on Twitter: Eric Topol (@EricTopol): Great to see US Covid hospitalizations down to 23,000 and approaching their pandemic low But indicators from the new wave in Europe and US wastewater surveillance suggest this may be short-lived pic.twitter.com/lwl6u0a5YL → https://twitter.com/EricTopol/status/1503542147584126976 | 02:30 |
| de-facto | afaik moderna was 100-100-50 | 02:30 |
| Tuvix | Because people buy into the "but now that we got so many infected we can't possibly have that kind of a wave again" fallacy. | 02:30 |
| de-facto | yeah thats nothing but trying to align perception with wishful thinking | 02:31 |
| de-facto | at some point we would have to get honest and look at the data though | 02:31 |
| Tuvix | Lots of EU is seeing what may be a BA.2 (plus removing restrictions) increase, but the US never really "recovered" from Delta. Even now in what should be the Omicron _recovery_ (pre-BA.2 period) we're once again stuck at a death rate no better than post-Delta. | 02:31 |
| Tuvix | For a week running the death toll nationally in the US has been quite flat: https://covid.cdc.gov/covid-data-tracker/#trends_dailycases_newhospitaladmissions | 02:32 |
| de-facto | maybe if people try to wonder about repeating patterns in a few years more will abandon wishful thinking and look more honestly at the data itself | 02:32 |
| Tuvix | Even as cases & hospitalizations have continued to fall, so something is still causing lots of death that isn't matching the expected 3-4 week delay in continued recovery from death. | 02:32 |
| Tuvix | (and nevermind long-COVID which is a real issue too; I use death because it's a more firm metric that's easier to plot) | 02:32 |
| de-facto | its going to repeat now, every year, until enough motivation is gathered to change something about it | 02:33 |
| Tuvix | Problem is that ignoring data on purpose seems to be a new trend, especially in the US. We saw it pre-COVID with the election mess too :( | 02:33 |
| Tuvix | COVID is just the new fun thing to pretend isn't a real problem. | 02:33 |
| de-facto | in my opinion there is only one way to end this: cut down transmission paths, absolutely strictly with no exceptions and continue to do so until the last case extinguished then prevent imports at any price | 02:34 |
| Tuvix | I don't really think that's realistic; it'd be nice if it were, but if even China can't manage it, I don't see how that would be viable anywhere else. | 02:34 |
| de-facto | but that wont happen soon, hence it will continue | 02:34 |
| de-facto | mainland China ? | 02:35 |
| Tuvix | I'd settle for more data-drive responses. In theory that's what some political leaders promissed, but haven't really delivered on. | 02:35 |
| de-facto | https://www.worldometers.info/coronavirus/country/china/ | 02:35 |
| Tuvix | China seems to be struggling with localized outbreaks requiring entire cities to be effectively locked down; that kind of thing just won't fly in most of EU & the Global West. | 02:35 |
| de-facto | in my opinion way to many compromises are being made, every single one is in favor of pathogen reproduction though | 02:36 |
| de-facto | hence management basically ensures to keep Rt > 1 at all times and instantly prevents any situation where Rt < 1 by opening transmission paths as soon as a peak is reached | 02:37 |
| de-facto | here as soon as the peak was reached and cases began to go down for a few *days* everyone was screaming about "opening up" and "freedom day" etc | 02:38 |
| de-facto | so opening up successfully prevented case numbers to continue to go down, just as expected from observing previous situations like this | 02:38 |
| de-facto | now they are going up again, and they still demand opening up more transmission paths, dropping masks in schools etc | 02:39 |
| de-facto | obviously they intend to infect more kids in school for some reaosn | 02:39 |
| de-facto | i dont understand their intent, it does not make any sense to me anymore | 02:39 |
| Tuvix | That's just the "cost of freedom" to them. The claim seems to be that either so many have been exposed that it's a non-issue, but data doesn't agree. | 02:40 |
| de-facto | they either have the intention to ruin more peoples health or they fail to act deterministic according to the data | 02:40 |
| Tuvix | Not sure about abroad, but the under-18 death rates ave never been _better_ than the _worst_ of the Alpha wave for the under-18's here: https://imgur.com/a/JlnZAFl | 02:40 |
| Tuvix | Just think about that for a moment: the _best_ month post-Delta has been _just_ as bad as the peak of Alpha for that age, and actually all ages under 50 (within about 10%) | 02:41 |
| Tuvix | The EU and Canada did a bit better, but BA.2 and relaxing mitigations seems to have changed that now. | 02:41 |
| de-facto | the next mutant is just about to get created, and then the next after that etc | 02:42 |
| de-facto | reinfections will happen, more people will end up suffering from long covid, less people will be fully productive because of brain damage and so on | 02:42 |
| de-facto | or chronic fatigue syndrome, or damaged heart or lung fibrosis | 02:43 |
| Tuvix | If we can get better diagnostics of long-covid, I wonder if businesses would be for stamping this out if they had to be on the hook for what in the US is termed "worker's comp" which is basically disability leave. | 02:44 |
| Tuvix | As in, if your business doesn't take mitigations and I end up suffering with long-term symptoms we can link to that workplace, if the employer had to pay for my time off without the benefit of an employee doing productive work, they'd be more inclined to keep the workplace safe. | 02:44 |
| Tuvix | I guess the challenge there is they just say "you must have caught it while shopping" and everyone just pretends this is a problem for someone *else* to deal with. | 02:45 |
| de-facto | especially countries that rely on the mental capacity of their worker class will get an impact from having significant parts of their working force suffer from long COVID induced brain fog | 02:45 |
| Tuvix | Basically the classic Prisioner's Delema | 02:45 |
| de-facto | governments really should focus on ONLY one thing: guarantee Rt < 1 at all times | 02:46 |
| de-facto | everything else should be secondary to that | 02:47 |
| Tuvix | I'd prefer an approach that looks at outcomes. | 02:47 |
| de-facto | havent we tried to do so for 2 years now? | 02:47 |
| Tuvix | Influenza has Rt > 1 every season, but outcomes are managalbe; yes, some die, but 12x less than my country sees this past week with COVID. | 02:47 |
| Tuvix | I don't really think we've tried; we've compromised with the anti-vax, anti-mitigation folks because that's what politicans to. | 02:48 |
| Tuvix | do* | 02:48 |
| de-facto | its not only about dying, its about ruining the health of significant parts of populations | 02:48 |
| Tuvix | At this point even the CDC has effectively given up, and an article I found really interesting basically pointed out that you can't have rules more strict than your population is willing to accept. For an extreme examples of that, see Ukraine where they don't accept the "new" military attempt to change their society. | 02:49 |
| de-facto | we tried here to look at hospitalizations for steering through the waves: it brought us the highest infection numbers EVER | 02:49 |
| de-facto | and probably the highest rates of producing destinies for people that will now have to deal with long-COVID | 02:49 |
| Tuvix | Well, that's what the US is now doing, and that's of course a lagging indicator. So, what, after cases from the next surge are already on the downswing again, _then_ we go and put in place strict mandates? Who on earth is going to believe the government if they actually do enact restrictions then? | 02:50 |
| de-facto | will they get recognized by statistics? no they probably will get brushed off by telling them their problems are psychosomatic and that they just should focus more when they complain about brain fog or such | 02:50 |
| Tuvix | Disability activistists are already worried about that, since many places don't treat the disabled very well to begin with, and this is even harder than a more accute condition. | 02:51 |
| Tuvix | Long-COVID being in the post-acute phase after the normal recovery from more obvious symptoms (fever, etc) | 02:51 |
| Tuvix | I just heard a podcast about that topic actually, and a pre-COVID disabled woman was actually upset that "all it took" was COVID and she got the ability to work remotely, after being told for years she couldn't be supported by employers when she mad the request for her disability. | 02:52 |
| Tuvix | We're probably headed back that way to some degree when employers realize they can just bully people into doing what the managers want. Frankly, my opinion is if you have employees that can work remotely and you can't manage them effectively, you've hired unreliable people and should replace them. | 02:53 |
| de-facto | i stay with what i always said: its a *gigantic* mistake to let a new pathogen (SARS-CoV-2) burn through the most important parts of a population (children and working age) that shows signs of being able to damage the health of a significant part of people it infects (probably two digit percentages) on a very long timescale (many months, hence long-COVID) with unknown outcome | 02:54 |
| dTal | well shit you finally convinced me | 02:54 |
| de-facto | i am not saying that everyone that got it will develop long COVID or such, yet the chances may be worse than Russian Roulette for some groups to develop long COVID after getting contaminated | 02:58 |
| de-facto | its not that those people will be unable to function, but they will be quite unsatisfied with the reduction in their abilities compared to what they used to be | 02:59 |
| de-facto | and afaik we still do not know how long-term long COVID really is, hence in my view its insane to just rely on wishful thinking (that its not going to last longer and just magically disappear by itself after some time) and based on that decide to expose everyone in a productive and healthy population | 03:00 |
| Tuvix | Even if most (what is "most" here?) do eventually recover (months? a year? how much recovery?), it's still a bad idea to ignore it. We really do need more research into this. | 03:01 |
| Tuvix | Dunno how interseted governments are going to be to *fund* that research though… | 03:02 |
| de-facto | yea and until we know with very high probability that long COVID is just a minor issue that will resolve itself or is easily treatable we urgently need to stop infecting more people | 03:02 |
| de-facto | not the other way around | 03:03 |
| de-facto | because until we have that knowledge we unfortunately would have to assume: long COVID is a longterm issue and we may not have the knowledge how (or possibility) to cure it | 03:04 |
| Tuvix | Sure, but why the willful ignorance of that possibility? We've seen this before with diseases like STIs or shingles, but there we worked to develop if not vaccines, some treatments and cut down on paths (in the case of STIs anyway) that led to unnecessary spread. | 03:07 |
| de-facto | an empiric approach would be using a principle of caution: extrapolate from datapoints we have and establish a confidence range around that trajectory and try to avoid damage by staying outside of the range of possible damage to the health of majorities | 03:07 |
| Brainstorm | New from COVID on Twitter: Eric Topol (@EricTopol): 85% of Covid infections were asymptomatic in a prospective, rigorous household South African study w/ 116,000 nasal swabs in 1,200 urban and rural household members. Transmission was the same, irrespective of the presence of symptoms. Pre-omicron. thelancet.com/journals/lanin… → https://twitter.com/EricTopol/status/1503551981667110913 | 03:11 |
| Tuvix | There was another study a couple weeks back that focused on household-transmission. I took 2 things away from that one: 1) mitigations do matter, even in settings where you're in close-contact with an infected case for hours, and 2) the infection rate even of those taking at least some mitigations is still pretty high. | 03:13 |
| Tuvix | %title https://www.cdc.gov/mmwr/volumes/71/wr/mm7109e1.htm?s_cid=mm7109e1_w | 03:13 |
| Brainstorm | Tuvix: From www.cdc.gov: SARS-CoV-2 B.1.1.529 (Omicron) Variant Transmission Within Households â Four U.S. Jurisdictions, November 2021âFebruary 2022 | MMWR | 03:13 |
| Tuvix | Oh, blah, my CDC link earlier didn't show the deaths, crap. This is the one showing the dreadfully "flat" last week of post-Omicron-peak recovery that seems to have stalled again basically just where the post-Delta death rate stopped: https://covid.cdc.gov/covid-data-tracker/#trends_dailydeaths_newhospitaladmissions | 03:17 |
| Tuvix | stopped recovering, that is. | 03:19 |
| LjL | Tuvix, "see Ukraine where they don't accept the "new" military attempt to change their society" they may not accept it but Russia seems pretty set on razing more and more of their cities down until they either do, or there's no one left to ;( | 03:45 |
| Tuvix | I mean, even their own population thinks it's a stupid war and he can only contain them domestically by lying and trying his best to cut down on widespread official discussion of it. | 03:46 |
| Tuvix | At least with COVID the discussion is available and open for those who want to learn more, generally speaking. | 03:46 |
| LjL | Last year, journalists used some of the data to calculate the true impact of the COVID-19 pandemic on Belarus (the excess mortality rate was 14 times higher than the official numbers) https://www.fastcompany.com/90730789/cyber-partisans-hacking-belarus-putin-ukraine-invasion | 03:53 |
| Tuvix | Yea, the excess mortality figures are just shocking, this as the US "official" numbers are approaching a million, in reality much higher when you account for the true cost. | 04:03 |
| Tuvix | 14x is a lot more of course, but not all countries do as good of a job (or even have the ability to.) | 04:03 |
| Brainstorm | New from COVID on Twitter: Eric Topol (@EricTopol): Wastewater surveillance of Covid is relatively sparse in the US, but 62 (15%) sites have a >1000% increase in viral RNA detected in the past 15-day periodcovid.cdc.gov/covid-data-tra… pic.twitter.com/aOSmkR9C7E → https://twitter.com/EricTopol/status/1503571864861388802 | 04:24 |
| Brainstorm | New from COVID on Twitter: Tomás Aragón, MD, DrPH (@DrTomasAragon): "The comparatively milder infections with the Omicron variant and higher levels of population immunity have raised hopes .... ongoing rapid antigenic evolution is likely to produce new variants that may escape immunity and be more [... want %more?] → https://twitter.com/DrTomasAragon/status/1503607370462556162 | 07:15 |
| Brainstorm | New from r/Coronavirus: Daily Discussion Thread | March 15, 2022: Please refer to our Wiki for more information on COVID-19 and our sub. You can find answers to frequently asked questions in our FAQ , where there is valuable information such as our: → https://old.reddit.com/r/Coronavirus/comments/tej1ud/daily_discussion_thread_march_15_2022/ | 08:04 |
| Brainstorm | New from COVID on Twitter: Jeffrey Barrett (@jcbarret): Small shred of good news for Hong Kong: looks like the current wave is BA.2, rather than BA.1. Small number of sequences, so hard to be certain, but looks likely that they, like Denmark, will not have a two-part Omicron wave. cov-spectrum.org/explore/Hong%2…* → https://twitter.com/jcbarret/status/1503630607338905600 | 08:23 |
| Brainstorm | New from COVID on Twitter: Jeffrey Barrett (@jcbarret): @jburnmurdoch @JamesWard73 Yeah, the parsimonious explanation is BA.2 in mainland China as well. → https://twitter.com/jcbarret/status/1503644547565375491 | 09:19 |
| Brainstorm | New from StatNews: Business: STAT+: Patients are flocking back to hospitals, but volumes are at the mercy of Covid surges, new documents show → https://www.statnews.com/2022/03/15/hospital-patient-volume-covid/ | 09:48 |
| saviorisreal[m] | I The Savior Will Reveal The Deadly Loophole Of Current Financial System If Receive Donation https://www.reddit.com/r/thesaviorvoice/comments/tek6f2/i_the_savior_will_reveal_the_deadly_loophole_of/ | 09:51 |
| Brainstorm | New from StatNews: Opinion: Covid-19 and telehealth: Holding on to the gains of remote care: The big question for telehealth: "Will the pendulum swing back to how things used to be, or has the pandemic opened the door to new ways of delivering care?" → https://www.statnews.com/2022/03/15/covid-19-telehealth-holding-gains-remote-care/ | 09:57 |
| Brainstorm | New from COVID on Twitter: Marc Veldhoen (@Marc_Veld): SARS-CoV-2 incidence, transmission, and reinfection in a rural and an urban setting: results of the PHIRST-C cohort study, South Africa, 2020–21Pre-Omicron; transmission high, independent of symptoms.thelancet.com/journals/lanin… → https://twitter.com/Marc_Veld/status/1503664777897381888 | 10:35 |
| Brainstorm | New from COVID on Twitter: Marc Veldhoen (@Marc_Veld): --85·3% SARS-CoV-2 infections were asymptomatic --a limited role for control measures targeting symptomatic individuals. → https://twitter.com/Marc_Veld/status/1503664780200062978 | 10:45 |
| Brainstorm | New from r/Science: science: Fourth shot “is necessary” Pfizer CEO says as experts monitor BA.2 → https://old.reddit.com/r/science/comments/telbtk/fourth_shot_is_necessary_pfizer_ceo_says_as/ | 11:42 |
| Brainstorm | New from Politico: Frans Timmermans tests positive for COVID-19: EU Green Deal chief pulls out of major agriculture conference after catching coronavirus. → https://www.politico.eu/article/frans-timmermans-tests-positive-for-covid-19/ | 12:22 |
| Brainstorm | New from r/COVID19: COVID19: Exercise may help treat long COVID-induced diabetes, depression: New Study reveals → https://old.reddit.com/r/COVID19/comments/ten0jm/exercise_may_help_treat_long_covidinduced/ | 12:51 |
| xx | exercise helps with everything, just like becoming no longer fat | 12:55 |
| xx | why is there even a study for that? Who funded it? Wasted taxpayer money. | 12:55 |
| Brainstorm | New from WebMD: America’s College Mental Health Crisis: There’s one group the pandemic has hit with a particularly vicious wallop: college students → https://www.webmd.com/brain/features/college-mental-health-crisis-mpi | 13:01 |
| Brainstorm | New from Contagion Live: us: Moderna Begins its Phase 1 HIV Trimer mRNA HIV Vaccine Trial → https://www.contagionlive.com/view/moderna-begins-its-phase-1-hiv-trimer-m-rna-hiv-vaccine-trial | 14:46 |
| Brainstorm | New from COVID on Twitter: Gunhild Alvik Nyborg (@GANyborg): “Learning to live with”Or die with -Almost impossible to follow data in Norway as few are tested & almost no tests are sequenced. Many are infected for 2.-3. time in 1-3 months. The @Folkehelseinst have seemingly decided this pandemic is over. [... want %more?] → https://twitter.com/GANyborg/status/1503732097600655363 | 15:05 |
| Brainstorm | New from COVID on Twitter: Gunhild Alvik Nyborg (@GANyborg): But v hard to interpret even these figures when we lack so much info e g proportion of total population infected at end of this period. Have to look at excess mortality+. Shame 1 of the ’s richest countries not contributing more to pandemic surveillance [... want %more?] → https://twitter.com/GANyborg/status/1503735655733542918 | 15:15 |
| Brainstorm | New from COVID on Twitter: Eric Topol (@EricTopol): The need for booster shots compromised the crucial goal of global vaccine equityft.com/content/61e1d5… @donatopmancini @JamieSmythF pic.twitter.com/tGl7ux0wmP → https://twitter.com/EricTopol/status/1503736349764952065 | 15:25 |
| Brainstorm | New from COVID on Twitter: Dr Emma Hodcroft (@firefoxx66): Omicron may be mild-er, but it's far from mild, if your most vulnerable populations don't have protection from vaccination (or previous infection).Hong Kong is a stark reminder of critical vaccines, and where you are left without them, even with 'mild' [... want %more?] → https://twitter.com/firefoxx66/status/1503739064406716424 | 15:35 |
| Brainstorm | New from COVID on Twitter: Eric Topol (@EricTopol): @ScienceTM Omicron's impact on reinfection in South Africascience.org/doi/10.1126/sc… by @SACEMAdirector and colleagues pic.twitter.com/Eg6RrQB8G0 → https://twitter.com/EricTopol/status/1503743941627232256 | 15:54 |
| Brainstorm | New from BBC Health: Covid in Scotland: Mask rules will stay in force until April: Other restrictions will be dropped on 21 March, but face masks will remain due to a rise in Covid-19 cases. → https://www.bbc.co.uk/news/uk-scotland-60750364 | 16:04 |
| Brainstorm | New from COVID on Twitter: Eric Topol (@EricTopol): Evidence of small airways disease and air trapping in people with #LongCovid symptoms in a prospective study compared with healthy controls, independent of initial infection severity (small N) pubs.rsna.org/doi/pdf/10.114… @radiology_rsna → https://twitter.com/EricTopol/status/1503748651490988035 | 16:14 |
| Brainstorm | New from COVID on Twitter: Michael Lin, MD PhD (@michaelzlin): Pretend play, COVID-style Who says testing can't be fun? pic.twitter.com/j3EvVwAHTN → https://twitter.com/michaelzlin/status/1503754497436356618 | 16:33 |
| Brainstorm | New from LitCovid: (news): Crimean-Congo hemorrhagic fever in the COVID-19 pandemic: A case study. → https://www.ncbi.nlm.nih.gov/research/coronavirus/publication/35280091 | 16:43 |
| Brainstorm | New from Reddit (test): Tuesday 15 March 2022 Update: submitted by /u/HippolasCage to r/CoronavirusUK → https://old.reddit.com/r/CoronavirusUK/comments/tesd83/tuesday_15_march_2022_update/ | 17:41 |
| Brainstorm | New from BMJ: The NHS isn’t alone in its problems—but other countries can help with solutions: The government has unveiled plans for how the UK might live with covid-19, but the consequences of the pandemic for the NHS are still unfolding.1 In December 2021, the number of patients waiting for... → http://www.bmj.com/content/376/bmj.o691.short | 17:51 |
| Jigsy | UK back at 100,000 cases. | 18:04 |
| Jigsy | Holy fuck, it was 170,000 yesterday? | 18:05 |
| mrdata | ontario did something like that, too | 18:06 |
| mrdata | idk | 18:06 |
| mrdata | there may be some fuzz in reporting between suspected and confirmed cases | 18:07 |
| mrdata | so when data gets cleaned, and a suspected case turned out not to be real, it must be removed | 18:07 |
| Brainstorm | New from StatNews: Inside the push for a permanent pandemic preparedness office at the White House: The Senate health committee is set to mark up a major pandemic preparedness package that includes a brand-new, permanent White House office. → https://www.statnews.com/2022/03/15/inside-the-push-for-a-permanent-pandemic-preparedness-office-at-the-white-house/ | 18:11 |
| Brainstorm | New from COVID on Twitter: Eric Topol (@EricTopol): The BA.2 triad.The new wave in Europe has 3 inter-dependent underpinnings. BA.2 has ~30% more transmission than BA.1. Less restrictions and more waning immunity will increase that further. pic.twitter.com/saWZm90CXq → https://twitter.com/EricTopol/status/1503782013463015427 | 18:21 |
| Brainstorm | New from Ars Technica: Science: Florida health official put on 2-month leave after urging staff to get vaccine → https://arstechnica.com/?p=1841226 | 19:00 |
| Brainstorm | New from r/COVID19: COVID19: Postpartum depression and associated risk factors during the COVID-19 pandemic → https://old.reddit.com/r/COVID19/comments/tevg42/postpartum_depression_and_associated_risk_factors/ | 19:09 |
| Brainstorm | New from The Atlantic: Is It Time for Second Boosters Yet?: Imagine if older Americans had been forced to weather the past three months without the option of a booster shot. Having an additional vaccine dose during the Omicron surge cut seniors’ risks of hospitalization and [... want %more?] → https://www.theatlantic.com/health/archive/2022/03/vaccine-second-booster-shot-seniors/627069/ | 19:19 |
| Brainstorm | New from CIDRAP: Study highlights risk of low COVID vaccine uptake in prison staff: Mary Van Beusekom | News Writer | CIDRAP News Mar 15, 2022 Fully 61% of guards and 36% of healthcare staff at California prisons were not vaccinated as of Jun 30, 2021. → https://www.cidrap.umn.edu/news-perspective/2022/03/study-highlights-risk-low-covid-vaccine-uptake-prison-staff | 19:28 |
| Brainstorm | New from r/COVID19: COVID19: Mild COVID-19 imprints a long-term inflammatory eicosanoid- and chemokine memory in monocyte-derived macrophages → https://old.reddit.com/r/COVID19/comments/tewkdx/mild_covid19_imprints_a_longterm_inflammatory/ | 19:47 |
| Brainstorm | New from COVID on Twitter: Michael Lin, MD PhD (@michaelzlin): Great news for SA. They relied heavily on J&J and provide much knowledge about J&J's lower efficacy vs other vaccines. They've now joined most of the world in recommending 2 boosters after J&J.Meanwhile the USA is still stuck on 1 booster only for [... want %more?] → https://twitter.com/michaelzlin/status/1503806769599971328 | 19:57 |
| Brainstorm | New from CIDRAP: NASEM report urges medical supply chain transparency, agility: Mary Van Beusekom | News Writer | CIDRAP News Mar 15, 2022 Medical supply chain disruptions "have the potential to seriously compromise patient care." → https://www.cidrap.umn.edu/news-perspective/2022/03/nasem-report-urges-medical-supply-chain-transparency-agility | 20:06 |
| Brainstorm | New from COVID on Twitter: Michael Lin, MD PhD (@michaelzlin): In case we needed another reminder, a paper just came out last week (one I had analyzed as a preprint) showing J&J + 1xPfizer was much better than J&J + J&J, and similar to 2xPfizer, finallysciencedirect.com/science/articl… pic.twitter.com/b6WRArMxQv → https://twitter.com/michaelzlin/status/1503810562181849089 | 20:16 |
| Brainstorm | New from WebMD: Pfizer's CEO Says Fourth COVID Shot Is Needed. Is He Right?: Some might be skeptical when the CEO of a vaccine manufacturing company calls for additional doses – do the experts agree? → https://www.webmd.com/vaccines/covid-19-vaccine/news/20220315/is-fourth-covid-shot-needed | 20:46 |
| Brainstorm | New from WebMD: Uncomfortably Numb: With COVID & Ukraine, Crisis Fatigue Thrives: Ongoing stress from the pandemic, Ukraine, inflation and other uncertainty have made some people turn off their feelings. But is that always a bad thing? → https://www.webmd.com/balance/stress-management/news/20220315/are-we-all-uncomfortably-numb | 21:05 |
| de-facto | %title https://www.youtube.com/watch?v=X0VguvLJaq0 | 21:17 |
| Brainstorm | de-facto: From www.youtube.com: China locks down cities to stop Omicron surge - YouTube | 21:17 |
| Brainstorm | New from COVID on Twitter: Eric Topol (@EricTopol): But it's not as simple as BA.2 and facilitatorsSome countries with BA.2 dominance show the pattern of a new increase in casesOthers do not. Case rise without BA.2 or no significant rise with BA.2covariants.org twitter.com/EricTopol/stat… pic.twitter.com/KKwFpLiAEV → https://twitter.com/EricTopol/status/1503848184375783424 | 22:42 |
| Brainstorm | New from COVID on Twitter: Marc Veldhoen (@Marc_Veld): Hospitalization of Infants and Children Aged 0–4 Years with Laboratory-Confirmed COVID-19 — COVID-NET, 14 States, March 2020–February 2022cdc.gov/mmwr/volumes/7… → https://twitter.com/Marc_Veld/status/1503848558721699843 | 22:51 |
| Brainstorm | New from COVID on Twitter: Marc Veldhoen (@Marc_Veld): Peak rates during Omicron predominance were approximately five times those of the peak during Delta predominance. Similarly, ICU admission rates during Omicron predominance peaked at approximately 3.5 times the peak rate during Delta predominance. → https://twitter.com/Marc_Veld/status/1503848561364152327 | 23:01 |
| Brainstorm | New from BioNTech: Pfizer and BioNTech Submit for U.S. Emergency Use Authorization of an Additional Booster Dose of their COVID-19 Vaccine for Older Adults: Submission based on real-world safety and efficacy data from Israel Data showed rates of [... want %more?] → https://investors.biontech.de/news-releases/news-release-details/pfizer-and-biontech-submit-us-emergency-use-authorization | 23:10 |
| LjL | %print https://twitter.com/alexmeshkin/status/1503840867513036801 | 23:35 |
| Brainstorm | LjL, It says: Alex Meshkin, GED (@alexmeshkin): "Not treating BA.2 as a separate VOC seems to be backfiring" | Hungary-based nitter instance by Hackerspace Szeged | 23:35 |
| LjL | remind me, *why* don't we consider it a separate variant given all the additional mutations it has (and/or lacks)? | 23:36 |
| LjL | if it's really closer to Delta than it is to BA.1, i really can't see how it isn't just a political decision | 23:36 |
| Tuvix | Perhaps some kind of peverse "varient fatigue" where people just don't want to hear about another VoC so soon, but indeed, this may encourage more people to do nothing. | 23:37 |
| Tuvix | Then again, the uptick in first-time-vaccine-recipients in the US anyway after Omicron was announced (just after our Thanksgiving holiday as it happens) was pretty small. Yes, it went up, but just slightly and quickly returned to the ever-decreasing new-vax rates despite the US having one of the lowest rates of our peer nations. | 23:39 |
| Tuvix | I'm not sure a new VoC name would really change people's actions much. | 23:39 |
| Tuvix | I'm still reading through the MMWR linked earlier today about children 0-4 having an uptick in severe outcomes (hospital & ICU) but really, if we can't get our act together "for the children" (literally and the cliché meaning here) then when can we start treating this seriously? 10x more death? A fifth of the workforce missing in a region that gets especially hard-hit? | 23:41 |
| LjL | i'm not sure if it would change how people act but i think it's not a good idea to decide whether or not to name it a variant *based* on what you want people to react like ;( | 23:42 |
| LjL | it should kinda be based on scientific-ish reasons, innit | 23:43 |
| Tuvix | Daily CDC trends update is published a bit earlier today, and shows a continued flat-trend of death, despite still-improving measures of hospitalization & cases nationally. Looks like COVID is still finding plenty of lives to take. | 23:43 |
| Tuvix | True, although it took us a bit of time to identify first BA.2 and then its differnces and reinfection & what appears to be a slightly better transmission rate. It could also be a case of data coming in too slowly and it had sort of already been classified as a sub-varient of Omicron at that point. | 23:44 |
| Tuvix | Really that just means informed people would distinguish BA.1 from BA.2 in that context, just like people who are slightly-less-careful might only compare Omicron to Delta, and even-less-careful people just call it COVID. | 23:45 |
| Tuvix | I don't get too hung up on sematics of what we call it, but the impact it has globally and in my region, and how well we're responding to it. Perhaps the flat, no-longer-improving death-rate in the US is just a bump in the road, but I don't like that it flattened out at the high rate we saw after the Delta peak either. | 23:46 |
| Tuvix | This is a really good article on the topic of what I might call willful ignorance of the continued toll on society: https://www.nytimes.com/interactive/2022/02/01/science/covid-deaths-united-states.html?auth=login-email&login=email | 23:48 |
| Tuvix | (that may require a free account, but it's not pay-walled.) | 23:48 |
| Tuvix | The best quote is perhaps the one at the very end: “If we want to declare the end of the pandemic right now, what we’re doing is normalizing a very high rate of death.” | 23:48 |
| Tuvix | 7-day moving aveage death toll as of today's CDC update is over 1100 COVID-fatalities, daily, and that rate has been flat for over a week now: https://covid.cdc.gov/covid-data-tracker/#trends_dailydeaths_newhospitaladmissions | 23:50 |
| Tuvix | The data rings true to that article, which was published during the peak of the Omicron cases 6 weeks back now :\ | 23:51 |
| Tuvix | Sorry, peak of the rate of death, rather. | 23:51 |
| LjL | Tuvix, not quite to play devil's advocate, i do see that declaring "the end of the pandemic" seems surreal when it simply... hasn't ended; but, what else should we be doing, apart from the "zero covid" option that i think you agree nobody is willing or able to pursue? we have supposedly good vaccines, and we now have more than enough of them for everybody, so whoever wanted not two but *three* shots, could get them; in europe we've also "encouraged" the ones who | 23:59 |
| LjL | didn't want to a little bit, maybe you've done it a bit less in the US, but there are cultural reasons that would make it harder; we also have effective treatments like Paxlovid (well, mainly Paxlovid), although somehow we haven't quite figure out that we should *give them to people* when they start showing symptoms instead of waiting >1 week for testing. so what is left? restrictions is the big one. if we say the pandemic has ended, we remove restrictions. but in | 23:59 |
| LjL | the US, as you always say, you barely had them. but even if you *did* have them, or if you could/would introduce a bunch of them right now... after two years of struggling, can the economy cope with such restrictions? also now that there is a war with a ton of sanctions? | 23:59 |
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