libera/##covid-19/ Wednesday, 2022-03-23

BrainstormNew from The Lancet (Online): [Correspondence] Ritonavir and COVID-19: pragmatic guidance is important: We thank Joseph Heskin and colleagues1 for highlighting the crucial issue of drug–drug interactions (DDIs) with ritonavir, the pharmacoenhancer or booster co-formulated with the novel [... want %more?] → https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(22)00280-X/fulltext00:34
BrainstormUpdates for Germany: +116890 cases, +126 deaths since 7 hours ago01:00
LjLhttps://www-punto--informatico-it.translate.goog/immuni-rimane-data-dismissione/?_x_tr_sl=auto&_x_tr_tl=en&_x_tr_hl=en&_x_tr_pto=wapp01:20
LjLSOGEI also specifies that " The contact tracing functions are linked to the availability of the GAEN framework by Apple and Google ", a project that is currently being extended for the whole of 2022.01:21
LjLi must say that the extension of the framework's duration went pretty quiet compared to the flashiness of the initial dialog boxes that told you about how data would be handled01:21
LjLanyway de-facto this is true for CWA and all of these apps too, if they don't extend it further, it'll be over at the end of the 202201:22
LjL<Brainstorm> New from r/WorldNews: worldnews: NZ Government removes vaccine pass, most vaccine mandates, and outdoor gathering limit → https://old.reddit.com/r/worldnews/comments/tkgdkw/nz_government_removes_vaccine_pass_most_vaccine/01:50
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): Very good to see: "There are no discernable differences in the effects of prior infection, vaccination, and hybrid immunity against BA.1 versus BA.2" New large study from Qatar. See Figure below for VE level of protection vs BA.2 hospitalization and death [... want %more?] → https://twitter.com/EricTopol/status/150643117812694221101:52
LjL<Brainstorm> New from r/WorldNews: worldnews: WHO blames rising Covid cases in Europe on curbs lifted too soon → https://old.reddit.com/r/worldnews/comments/tkhm00/who_blames_rising_covid_cases_in_europe_on_curbs/01:54
BrainstormUpdates for Slovakia: +11338 cases since 13 hours ago — Channel Islands: +3337 cases, +2 deaths, +4617 tests since a day ago02:03
BrainstormNew from r/COVID19: COVID19: A spatiotemporal machine learning approach to forecasting COVID-19 incidence at the county level in the USA → https://old.reddit.com/r/COVID19/comments/tkihbb/a_spatiotemporal_machine_learning_approach_to/02:30
Aarch64debianwhat is  usa civid poicy now02:47
Aarch64debian?02:47
BrainstormNew from COVID on Twitter: Michael Lin, MD PhD  (@michaelzlin): Tip to @PressSec: Now that you're sick again, you will get a natural boost, but you are on schedule for your 3rd COVID19 infection from BA.2 around August. Try to get POTUS to schedule his next European trip for a different time. Unless you don't want [... want %more?] → https://twitter.com/michaelzlin/status/150644865552751411202:58
Aarch64debianOksanaa, ?03:18
LjLAarch64debian, don't just highlight random people please03:25
LjLi assume your question is "What is the USA COVID policy now?"03:25
LjLunfortunately the USA has many different policies by state03:25
LjLso you'd have to be more specific, although i don't live in the USA anyway03:25
LjL%print https://twitter.com/EnemyInAState/status/150637473127611188703:32
BrainstormLjL, It says: Chris Turnbull (@EnemyInAState): "It seems that the whole country is starting to go into a form of mini lockdown: schools closing, GPs closing, hospitals closing, no doubt many other things too: and we've only just started this wave–bear that in mind. THIS IS JUST THE START." | nitter03:32
LjLthis guy sounds a bit mad, but i can understand feeling mad when every country seems to have tacitly agreed that BA.2 is "nothing" even though it clearly isn't03:32
Justin[m]1This is crazy to me too. We have a chance to get this under control, and they lift all the mandates. It's stupid.03:34
Aarch64debianso why cant american make some effective medicines for this virus after 2 more years03:52
Aarch64debianJustin[m]1, what is your policy in there? is it censored for the infected03:53
Justin[m]1Most, maybe all, states have lifted mask requirements. Near me, most people do not wear them in public.03:59
Aarch64debianto get group immunities i think?04:01
BrainstormUpdates for United Kingdom: +1165 cases since 8 hours ago04:02
LjLAarch64debian, Paxlovid is a very effective medicine reducing deaths by 90% if taken timely.04:04
LjLnot sure why you'd expect only Americans to make medicines, though04:04
LjLhttps://twitter.com/paulatwal/status/1506455773278195713 wrecked04:06
Aarch64debianah its  five days 530$ in shanghai, and limited supply04:11
LjLyeah, production needs to be scaled up faster04:12
LjLbut even more importantly it needs to be given *early*, but instead, we're makign testing more difficult04:12
BrainstormNew from Reddit (test): Covid2019: Multi-organ impairment and Long COVID: a 1-year prospective study. → https://old.reddit.com/r/Covid2019/comments/tkm7st/multiorgan_impairment_and_long_covid_a_1year/05:48
BrainstormUpdates for Canada: +8244 cases since 14 hours ago06:01
BrainstormNew from COVID on Twitter: Michael Lin, MD PhD  (@michaelzlin): Here are actual data: Pfizer VE for Omicron = 66% at peaknejm.org/doi/full/10.10…… pic.twitter.com/C2VZH0q55E → https://twitter.com/michaelzlin/status/150649522666316596206:07
BrainstormNew from Reddit (test): CoronaVirus_2019_nCoV: Dangerous Myth: ‘We’ve Got All the COVID-19 Tools We Need’ → https://old.reddit.com/r/CoronaVirus_2019_nCoV/comments/tkml5n/dangerous_myth_weve_got_all_the_covid19_tools_we/06:17
BrainstormUpdates for Bavaria, Germany: +90846 cases, +120 deaths since 2 days ago — Baden-Wurttemberg, Germany: +70235 cases, +56 deaths since a day ago — Hesse, Germany: +33907 cases, +34 deaths since 2 days ago — Berlin, Germany: +18493 cases, +12 deaths since 2 days ago07:04
BrainstormNew from r/Coronavirus: Daily Discussion Thread | March 23, 2022: Please refer to our Wiki for more information on COVID-19 and our sub. You can find answers to frequently asked questions in our FAQ , where there is valuable information such as our: → https://old.reddit.com/r/Coronavirus/comments/tko4os/daily_discussion_thread_march_23_2022/08:02
BrainstormNew from COVID on Twitter: Marc Veldhoen (@Marc_Veld): CONCLUSION: There are no discernable differences in the effects of prior infection, vaccination, and hybrid immunity against BA.1 versus BA.2. Hybrid immunity resulting from prior infection and recent booster vaccination confers the strongest protection against [... want %more?] → https://twitter.com/Marc_Veld/status/150653344796742861008:31
BrainstormNew from COVID on Twitter: Covid Fact Check UK (@fact_covid): We’re still dealing with huge numbers of cases today, but COVID’s threat has been significantly diminished (in the UK at least) thanks to vaccines and the number of people who have been infected over that time. → https://twitter.com/fact_covid/status/150653382269072998508:41
BrainstormNew from StatNews: New Covid trial results may point toward better ways to study medicines: The battle against Covid-19 has been marked by false hope, as too many people embraced would-be cures. But there have also been important lessons about how to develop effective treatments. → https://www.statnews.com/2022/03/23/new-covid-trial-results-may-point-toward-better-ways-study-medicines/09:38
BrainstormNew from Reddit (test): Covid2019: Omicron remains lethal in the older and unvaccinated, former CDC chief warns → https://old.reddit.com/r/Covid2019/comments/tkpid8/omicron_remains_lethal_in_the_older_and/10:36
BrainstormNew from BMJ: David Oliver: Can the recovery plan for elective care in England deliver?: Even before the covid-19 pandemic hit the UK in 2020, waiting lists for elective outpatient appointments, investigations, and procedures were growing. Covid has rapidly increased already long waiting... → http://www.bmj.com/content/376/bmj.o724.short11:15
BrainstormNew from BMJ: Good riddance to the face-to-face medical conference: Oliver asks if covid has killed the medical conference.1 I hope so. I struggle to recognise his description of them.The opportunity to network or socialise is usually limited to a select few, while... → http://www.bmj.com/content/376/bmj.o749.short11:35
BrainstormNew from r/COVID19: COVID19: Vaccine effectiveness of two and three doses of BNT162b2 and CoronaVac against COVID-19 in Hong Kong → https://old.reddit.com/r/COVID19/comments/tkr1v8/vaccine_effectiveness_of_two_and_three_doses_of/11:45
BrainstormNew from Pfizer: Pfizer Announces Positive Top-Line Results for Phase 3 Trial of Etrasimod in Ulcerative Colitis Patients:  Anonymous (not verified) Wed, 03/23/2022 - 06:45 Wednesday, March 23, 2022 - 06:45am - ELEVATE 12 study met primary and key [... want %more?] → https://www.pfizer.com/news/press-release/press-release-detail/pfizer-announces-positive-top-line-results-phase-3-trial11:55
BrainstormNew from r/COVID19: COVID19: Far-UVC (222 nm) efficiently inactivates an airborne pathogen in a room-sized chamber → https://old.reddit.com/r/COVID19/comments/tkryfa/faruvc_222_nm_efficiently_inactivates_an_airborne/12:52
BrainstormUpdates for Vanuatu: +256 cases since 22 hours ago13:07
BrainstormNew from StatNews: Health: Moderna to ask FDA to authorize Covid-19 vaccine in children 6 months to 6 years → https://www.statnews.com/2022/03/23/moderna-to-ask-fda-to-authorize-covid-19-vaccine-in-children-6-months-to-6-years/13:12
BrainstormNew from COVID on Twitter: Josiah 'So Mild' Grindrod (@JT_Grindrod): This outcome was obvious to anyone who read about what happened to SARS 2003 survivors. Letting SARS-CoV-2 spread is a crime against humanity.. twitter.com/Daltmann10/sta… → https://twitter.com/JT_Grindrod/status/150660856754084660113:32
wakeup3 days with fever... is this normal? my eyes hurt13:40
undefined_bobwakeup: with covid-19? yeah sounds normal. do you drink enough water? How high is the fever? When in doubt you should ask your doctor13:49
peetaurstupid headlines....letting it spread when there is a clear effective other option should be a crime against humanity...but there isn't one13:54
peetaurand the way politics works is everything that looks clear is really just biased garbage, so if something actually valid came out, we will ignore it as we have been taught13:54
BrainstormNew from Contagion Live: Moderna’s COVID-19 Vaccine Mets Primary Endpoint in Phase 2/3 Trial in Children 6 Months to Under Six Years: Along with reporting positive data in the youngest pediatric population, the company is working [... want %more?] → https://www.contagionlive.com/view/moderna-s-covid-19-vaccine-mets-primary-endpoint-in-phase-2-3-trial-in-children-6-months-to-under-six-years14:01
undefined_bobpeetaur: which headline are you referring to?14:03
peetaurundefined_bob: the one saying "crime against humanity"14:03
undefined_bobI think I missed that one14:04
undefined_boblet me search14:04
undefined_bobah that twitter one14:04
undefined_bobI mostly ignore the twitter lines here14:04
peetauryeah most twitter related here is total garbage, but when they accuse you of crime against humanity, you can complain, right?14:05
undefined_bobI think its just a way of over exaggerate things to gain attention14:05
peetauryep, pschological tricks replace science in media and politics14:06
undefined_boband the long covid thing is still pretty unclear. But calling it 'crime against humanity' is a bit over the top for me. Russia is committing crimes against humanity, thats valid14:06
peetaurit seems every significantly large government or organization commits such crimes14:09
BrainstormUpdates for Cook Is.: +113 cases, +1755 tests since a day ago14:10
peetaureg. USA is corrupt and evil enough that propaganda like this is believable to many https://michaelsuede.substack.com/p/why-did-russia-invade-the-ukraine?s=r14:11
undefined_bobGermany stopped doing that like 77 years ago14:11
peetaurto sum up that article "ukraine is run by Nazis the CIA put in place because everyone's Nazis"14:12
undefined_bobno propaganda is propaganda and should not be spread14:12
undefined_bobbut thats so much bullshit14:12
undefined_bobbtw Nazis are such a yesterday thingy. No one cares anymore14:13
peetauras long as the conclusion is that all sides you hear about are corrupt and liars, not that any of this propaganda is honest, it seems fine to share it14:13
undefined_bobno14:13
undefined_bobsame as with covid fakenews. you just dont share it14:14
peetaurI think it's good to hear it and read about it before you hear it from some nutjob in person14:14
undefined_bobso that you can punch that person in the face when you hear it?14:15
peetaurno....the opposite14:16
peetauryou can see the people believe all kinds of crap they hear, and somehow people find the above article persuasive, so you might understand how their brain got broken and have some sympathy14:17
undefined_bobI run out of sympathy for such people a longer while ago14:18
undefined_bobI more and more believe and end solution would be favorable14:18
undefined_bobbut thats no no14:18
minthsympathy doesn't require tolerance14:19
peetauryou need a bit of sympathy or you are helping the whole 'divide and rule/conquer' process to get more violent and rapid14:19
undefined_bobmaybe thats needed14:20
undefined_bobthats true, minth14:20
minthfortunately there seems to be a strong correlation between wealthy countries and reasonable people in power (of course everything is relative...)14:20
undefined_bobbut what really makes me sad is how china sides with russia. I really really thought better of them14:21
BrainstormNew from StatNews: Pharma: STAT+: Pharmalittle: Moderna asks FDA to OK Covid shot for kids under 6; big generic maker to close U.S. plant → https://www.statnews.com/pharmalot/2022/03/23/covid19-vaccine-covax-fda-aurobindo-novartis-insulin/14:21
minthchina sides with china, and I think they are smart enough to see where this is going and will stay out of it14:22
undefined_bobthey are spreading russia disinforamtion in state media and recalling that its nato fault and all that. Its like they dont wanna understand14:23
minththey've always been ideologically opposed to democracy but they understand trade and respect power. That is enough.14:25
peetaurnothing wrong with being opposed to democracy... republic deprecates it; but it's because they want power...not for you, but against you; if they own you, they have more power14:37
undefined_bobthats annoying14:37
undefined_boband a reason why the world cant be a nice place14:38
peetaurit can be a much nicer place... it just takes more work because breaking things is so much easier than fixing things14:38
undefined_bobhow to fix ill minded people?14:39
peetaurit's very hard... they are ill minded because it suits the 'divide' part of 'divide and rule/conquer'14:39
peetaurif we are too busy fighting ourselves, how can we fight them?14:40
undefined_bobbut without so many ill minded people the 'people in power' wouldn't be so powerful anymore14:40
BrainstormNew from BMJ: BMA expresses gratitude and grief for doctors who died from covid: bmj;376/mar23_12/o752/FAF1faSarah Turton/BMA NewsChaand Nagpaul (centre), BMA council chair, this week addressed the guests at a BMA memorial service for doctors who have lost their lives to... → http://www.bmj.com/content/376/bmj.o752.short14:51
BrainstormUpdates for Laos: +2625 cases, +1 deaths, +6021 tests since a day ago15:06
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): BA.2 and the debate about the need for a 4th dose."The UK, Germany, France and Sweden are among countries offering fourth doses to the elderly and vulnerable." ft.com/content/3963f1… by @hannahkuchler @JamieSmythF @FT pic.twitter.com/XyHmOFvhWj → https://twitter.com/EricTopol/status/150663337873226138315:10
dTalpeetaur: the credibility rating of your link degraded into "russian propaganda" when I read the line "Putin’s invasion has the full support of the Russian public." Seen too many videos of protestors being arrested and other dramatic protests15:17
peetaurthose people arrested don't count in "russian public"  ;)15:18
peetaurit's how Stalin did it....why should Putin change what works?15:19
dTalI just wonder how informationally sheltered someone would have to be to take an article like that at face value15:20
dTalsocial media is covered in direct evidence that contradicts it15:20
undefined_bob^^15:26
BrainstormNew from Reddit (test): China_Flu: HRSA COVID-19 Uninsured Program Claims Submission Deadline FAQs → https://old.reddit.com/r/China_Flu/comments/tkupbu/hrsa_covid19_uninsured_program_claims_submission/15:40
BrainstormNew from COVID on Twitter: Michael Lin, MD PhD  (@michaelzlin): The bad part is VE vs Omicron was only 44% in 2-5yo. The fact that the same Ab levels gave 70% VE in young adults adds to Pfizer's results of lower VE in young kids vs young adults at the same Ab levels. As I wrote above this suggests diffs in immune [... want %more?] → https://twitter.com/michaelzlin/status/150664617609909453115:59
BrainstormUpdates for Niue: +4 cases since 13 days ago16:03
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): New data from Hong Kong on Coronavac and Pfizer vaccines implicates lack of vaccination and boosters in people of advanced age, not type of vaccine, for extreme fatality rates.2 doses: Coronavac less protective than Pfizer3 doses: equivalent [... want %more?] → https://twitter.com/EricTopol/status/150665044236890931516:19
BrainstormNew from WebMD: Organs Donated by People Who Had COVID Are Safe: A study finds organs from deceased donors who had COVID did not cause infection in recipients and posed no risk to health care workers. → https://www.webmd.com/a-to-z-guides/news/20220323/organs-donated-by-people-who-had-covid-are-safe-study16:38
BrainstormUpdates for Germany: +301068 cases, +351 deaths since 23 hours ago17:05
oerhekswhere does Brainstorm get its numbers?17:08
oerheksgermany +184,178 deaths +225  https://www.worldometers.info/coronavirus/17:08
BrainstormNew from COVID on Twitter: (translated) SBI - Immunology (@sbi_imuno): The “Webinar Series Immunology Without Borders: Immune responses to SARS-CoV-2”, promoted by @iuis_online, with the participation of researcher Akiko Iwasaki, will take place next Monday (28/3), at 3 pm (CEST time zone). (@VirusesImmunity): [... want %more?] → https://twitter.com/sbi_imuno/status/150666709521136026517:27
BrainstormNew from Reddit (test): Wednesday 23 March 2022 Update: submitted by /u/HippolasCage to r/CoronavirusUK → https://old.reddit.com/r/CoronavirusUK/comments/tkz6r8/wednesday_23_march_2022_update/17:37
BrainstormUpdates for Netherlands: +42788 cases, +16 deaths since 13 hours ago18:02
BrainstormNew from WebMD: Subsidized COVID Testing, Treatments, and Vaccines May End Soon: Without congressional action, federal funding that subsidizes anti-COVID weapons will come to a halt, which could worsen the pandemic. → https://www.webmd.com/lung/news/20220323/subsidized-covid-testing-treatments-vaccines-ending18:06
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): Thread on the BA.2 wave in England. This is not just about cases.—Hospital admissions increased 22% past week, may be decelerating—Need for mechanical ventilation up 10%—Deaths up 14% twitter.com/COVID19actuary… → https://twitter.com/EricTopol/status/150668746598944358518:45
BrainstormUpdates for Italy: +78358 cases, +153 deaths, +513744 tests since 23 hours ago19:11
BrainstormNew from COVID on Twitter: betsy ladyzhets  (@betsyladyzhets): very excited to share this one: for @FiveThirtyEight, I looked back at the metrics that the U.S. has used to track COVID-19 over the last two years -- and how our fractured public health system doomed each one. (1/5) [... want %more?] → https://twitter.com/betsyladyzhets/status/150669099831077683219:25
BrainstormNew from Contagion Live: us: Public Health Watch: Myocarditis Remains Rare Even After Multiple Doses of mRNA Vaccine → https://www.contagionlive.com/view/public-health-watch-myocarditis-remains-rare-even-after-multiple-doses-of-mrna-vaccine19:34
BrainstormUpdates for United Kingdom: +102513 cases, +194 deaths since 21 hours ago20:01
BrainstormNew from CIDRAP: COVID-19 Scan for Mar 23, 2022: COVID-19 vaccine against long COVID SARS-CoV-2 antibody levels in kids → https://www.cidrap.umn.edu/news-perspective/2022/03/covid-19-scan-mar-23-202220:13
LjLOf the participants, 47.2% experienced COVID-19 symptoms 1 year after infection, including 85 (30.6%) who reported the onset of new post-COVID-19 symptoms at 12 months. There were no significant differences in the worsening of post-COVID 19 symptoms (22.7% vs 15.8%, P = 0.209) among vaccinated (132) and unvaccinated (347) patients.20:43
LjL:(20:43
LjLthis sounds awful20:45
LjLit's about hospitalized (or "seen at hospital") patients, though20:45
LjLuhm actually, looking at the actual study https://www.clinicalmicrobiologyandinfection.com/article/S1198-743X(22)00155-0/fulltext it seems to be saying that the vaccination didn't worsen post-COVID symptoms, not that vaccinated people had the same amount of long COVID20:49
LjL(then again it didn't improve it either...)20:49
BrainstormNew from r/COVID19: COVID19: Sulforaphane exhibits antiviral activity against pandemic SARS-CoV-2 and seasonal HCoV-OC43 coronaviruses in vitro and in mice → https://old.reddit.com/r/COVID19/comments/tl9dmx/sulforaphane_exhibits_antiviral_activity_against/20:51
BrainstormNew from ##covid-19 Zotero group: COVID-19 Scan for Mar 23, 2022: Type Web Page URL https://www.cidrap.umn.edu/news-perspective/2022/03/covid-19-scan-mar-23-2022 Accessed 2022-03-23 19:53:28 Language en Website Title CIDRAP → https://www.zotero.org/groups/covid_links/items/P8RUAT9C21:01
BrainstormUpdates for Japan: +35766 cases, +122 deaths since 13 hours ago — Canada: +3937 cases since 23 hours ago21:03
LjL%cases japan21:13
BrainstormLjL: Japan has had 6.2 million confirmed cases (4.9% of all people) and 27373 deaths (0.4% of cases; 1 in 4601 people) as of 10 minutes ago. 42.2 million tests were done (0.3 per capita, 14.7% positive). 101.2 million were vaccinated (80.3%). +35766 cases, +122 deaths since 13 hours ago. See https://covid19japan.com/21:14
LjLhow on earth can we have 10x the amount of deaths from COVID as Japan, when okay, there may be a culture of obedience, but they never had any actual lockdowns, they only ever had *recommendations*21:15
de-factoits the behavior of majorities of people determining infection dynamics by transmission pathways, the pathogen does not care if people behave in a sane way due to being forced by law or due to having a reasonable nature by themselves21:19
BrainstormNew from WebMD: Metabolic Syndrome Ups Odds of ARDS, Death in COVID-19: Researchers found that people with metabolic syndrome were associated with an increased risk for intensive care unit (ICU) admission with COVID. → https://www.webmd.com/heart/metabolic-syndrome/news/20220103/metabolic-syndrome-ups-odds-of-ards-death-in-covid1921:20
LjLi don't buy it21:20
LjLi don't think japanese people are magical21:20
LjLTokyo is crammed with people, they haven't all stopped going shopping21:21
de-factohonestly i think a lot of people in western countries, including Germany, are exceptionally dumb21:21
de-factoextrapolating from movements like Querdenker or QAnon, i never heard of such things from e.g. Japan21:22
LjLhow much exposure to Japan's movements do you have21:22
de-factoi just doubt something like that could exist in their country, yet i cant prove that21:25
de-factoi know absence of evidence is not evidence of absence, hence i am only speculating21:26
LjLfair enough21:27
ArsaneritTokyo has had its subway sarin terrorist attack21:29
ArsaneritDumb people exist everywhere.21:29
de-factoyes of course, but i am assuming about their distributions in majorities of inhabitants of a location, the thing determining epidemiological dynamics21:32
de-factoid guess there is some sort of critical mass in terms of ratio of dumb to sane people in majorities of a population that determines (depending on a pathogens base reproduction number R0) if the time varying pathogen reproduction Rt can be kept below a value of 1 where exponential growth of daily new infections dominates21:37
ArsaneritR>1 → zombie apocalypse21:38
de-facto*Rt can be kept below a value of 1 where exponential growth of daily new infections dominating infection dynamics can be avoided21:41
LjLanyway, i hope Japan doesn't assume they're invulnerable, because http://offloop.net/covid19/?default=South%20Korea;Japan&byPopulation=yes&cumulative=no&legacy=no21:57
BrainstormUpdates for France: +145560 cases, +101 deaths since a day ago — Germany: +301404 cases, +331 deaths since 21 hours ago22:06
`St0nerwhat's the latest on boosters? wait for omicron specific? ba.1 or ba.2 specific? boost every 4 months and make pfizer/moderna rich?22:08
LjLthe variant-specific ones don't seem to make a lot of difference, according to Pfizer and Moderna22:12
LjLi think they may make a difference on future variants, but obviously that's just speculation22:12
LjLPfizer and Moderna have both applied to the FDA for a 4th booster for everyone, despite evidence of only modestly improving immunity22:13
LjLi don't think either has been granted, the FDA is in the process of evaluating them22:13
LjL“A fourth dose is marginal in protecting people from getting infected with Omicron and moderate in protecting them from symptomatic disease,” Gili Regev-Yochay, MD, coauthor of the NEJM study and a researcher at Sheba Medical Centre in Israel, told MSN recently. “But these were relatively healthy people as they were all healthcare workers. I recommend people at high risk to get the extra protection, even if it’s small. For vulnerable populatio22:15
LjLns, any additional protection is important. For others, it probably does not make sense to push on a fourth dose, at least not when there is no immediate threat from a new, more pathogenic variant.”22:15
LjLhttps://www.contagionlive.com/view/public-health-watch-myocarditis-remains-rare-even-after-multiple-doses-of-mrna-vaccine22:15
BrainstormNew from CIDRAP: Simple home oxygen monitors signal when to seek COVID care: Mary Van Beusekom | News Writer | CIDRAP News Mar 23, 2022 Experts review 13 studies and advise on how to use pulse oximeters to signal when medical care is needed. → https://www.cidrap.umn.edu/news-perspective/2022/03/simple-home-oxygen-monitors-signal-when-seek-covid-care22:19
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): Neutralizing antibodies (nAb) to Omicron BA.1 in people who only had this infection, no prior Covid or vaxx, are specific to BA.1, without cross-reactivity to other variants. Breakthrough Omicron infections among vaccinated had a good nAb response [... want %more?] → https://twitter.com/EricTopol/status/150674415435678105822:29
BrainstormNew from COVID on Twitter: Annika Rössler (@AnnikaRoessler): Happy to see our next omicron study on cross-neutralization of other VOCs after Omicron Infection published @NEJM @JanineKimpel @knabl_l @DorotheeLaer #imed_tweets #GetVaccinatedNow #omicron #SARSCoV2 nejm.org/doi/full/10.10… pic.twitter.com/g1o4DhUXPs → https://twitter.com/AnnikaRoessler/status/150674473230688665622:39
BrainstormUpdates for Norway: +170 deaths since 20 hours ago — United Kingdom: +103185 cases, +196 deaths since 19 hours ago23:02
BrainstormNew from COVID on Twitter: Tatiana Prowell, MD (@tmprowell): Translation: If you are counting on a past #Omicron infection to keep you safe from other or future #COVIDvariants, that’s not a good strategy. You need to #GetVaccinated.  #MedTwitter twitter.com/erictopol/stat… → https://twitter.com/tmprowell/status/150674902574322074123:08
LjL%print https://twitter.com/EricTopol/status/150673755214497382923:51
BrainstormLjL, It says: Eric Topol (@EricTopol): "New @NEJM The only Phase 3 randomized trial of a booster, in >10,000 people, age 16+ –2 shots plus placebo vs 3 shots –95% efficacy for preventing breakthrough infections –Median follow-up 2.5 months, during Delta wave http://www.nejm.org/doi/full/10.1056/NEJMoa2200674" | Hungary-based nitter instance by Hackerspace Szeged23:51
LjLwut23:51
LjLeven if it's delta... wut23:51
LjLhow does it manage to be 95%23:51
LjL"The median interval between dose 2 and dose 3 was 10.8 months in the vaccine group and 10.7 months in the placebo group; the median follow-up was 2.5 months."23:52
LjLand it's taking people who did *not* (ever) get COVID23:52
LjLso isn't it kind of cherrypicking people who are somehow (for behavioral or genetic or other reasons) less prone not to get covid?23:53
LjL11 months is a long time23:53
LjLmost people got a third dose earlier than that23:53
BrainstormUpdates for Brazil: +47376 cases since 23 hours ago23:59

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