libera/##covid-19/ Tuesday, 2022-04-12

BrainstormUpdates for United Kingdom: +164 cases since 3 hours ago00:01
BrainstormNew from COVID on Twitter: Scott Gottlieb, MD (@ScottGottliebMD):  @trvrb on Covid evolution"The better baseline scenario is of continued antigenic drift within Omicron BA.1 and BA.2 rather than emergence of wildly divergent virus... The more time that passes, the more confident we can be that another [... want %more?] → https://twitter.com/ScottGottliebMD/status/151364692142402765700:39
BrainstormNew from COVID on Twitter: Dr Ed (@notdred): Whoa - would not have predicted that the results of Beta infection + mRNA vaccination would be so nice twitter.com/sigallab/statu… → https://twitter.com/notdred/status/151364938721760461200:58
BrainstormNew from COVID on Twitter: Marc Veldhoen (@Marc_Veld): This highlights that COVID19 vaccines are v safe, performing better against most vaccines in the past 75 years. That myocarditis is very mild compared to infection, but a true occurrence as a result not of a particular vaccine, but the strength of the immune [... want %more?] → https://twitter.com/Marc_Veld/status/151365380960366183101:08
BrainstormNew from r/COVID19: COVID19: SARS-CoV-2 spike L452R mutation increases Omicron variant fusogenicity and infectivity as well as host glycolysis → https://old.reddit.com/r/COVID19/comments/u1kk2y/sarscov2_spike_l452r_mutation_increases_omicron/01:47
BrainstormNew from r/Science: science: Covid-19 Vaccines Carry Low Risk of Heart Conditions, Studies Find → https://old.reddit.com/r/science/comments/u1lkm0/covid19_vaccines_carry_low_risk_of_heart/02:35
BrainstormNew from COVID on Twitter: Josiah 'So Mild' Grindrod (@JT_Grindrod): I got one of these as well from my employer. I was never asked for it once, despite traveling during the most arduous "lockdowns" twitter.com/DrJBhattachary… → https://twitter.com/JT_Grindrod/status/151367995641231360202:55
BrainstormUpdates for Cook Is.: +278 cases, +754 tests since 3 days ago — Canada: +171 cases, +5103 tests since 5 hours ago03:03
BrainstormNew from r/Science: science: Covid Smell Loss Linked To Damage In Brain, Study Finds → https://old.reddit.com/r/science/comments/u1mg5s/covid_smell_loss_linked_to_damage_in_brain_study/03:14
BrainstormNew from COVID19 Vaccine Tracker: valerie: AMMS: Ad5-nCoV → https://covid19.trackvaccines.org/vaccines/42/03:33
BrainstormNew from COVID19 Vaccine Tracker: valerie: Adimmune Corporation: AdimrSC-2f → https://covid19.trackvaccines.org/vaccines/63/03:43
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): We certainly need more anti-Covid pills, but a small trial that was stopped early with only 150 patients, claiming  >50% reduction of mortality (50% placebo ->20% drug) and fulfilling criteria to get an EUA, seems far-fetchednytimes.com/2022/04/11/hea… pic.twitter.com/11oYonS7rx → https://twitter.com/EricTopol/status/151371587693506150905:18
BrainstormUpdates for Germany: +162790 cases since 10 hours ago — New Zealand: +11408 cases, +14 deaths since 10 hours ago — United Kingdom: +178 cases since 10 hours ago06:11
BrainstormNew from Il Sole 24 Ore: (translated) The anti Covid pills arrive in pharmacies, a prescription from the family doctor will suffice: The drug agency should give the green light to simplify the use of antivirals in patients who risk severe Covid → https://www.ilsole24ore.com/art/le-pillole-anti-covid-arrivano-farmacia-bastera-ricetta-medico-famiglia-AEJWpNRB07:03
BrainstormNew from COVID on Twitter: Gunhild Alvik Nyborg (@GANyborg): «The change brings the WHO’s messaging in line with what a chorus of aerosol and public-health experts have been trying to get it to say since the earliest days of the outbreak.» Men i Norge er det null oppreisning å få. Mobberne leder fortsatt an. En [... want %more?] → https://twitter.com/GANyborg/status/151375685485738803208:01
BrainstormUpdates for Unknown, China: +22296 cases since a day ago — Shanghai, China: +3947 cases since 3 days ago — Saitama, Japan: +3661 cases since a day ago — Tasmania, Australia: +1974 cases, +2 deaths since a day ago08:03
BrainstormNew from r/Coronavirus: Daily Discussion Thread | April 12, 2022: Please refer to our Wiki for more information on COVID-19 and our sub. You can find answers to frequently asked questions in our FAQ , where there is valuable information such as our: → https://old.reddit.com/r/Coronavirus/comments/u1sx98/daily_discussion_thread_april_12_2022/09:10
BrainstormNew from r/COVID19: COVID19: COVID-19 and the Vasculature: Current Aspects and Long-Term Consequences → https://old.reddit.com/r/COVID19/comments/u1t54f/covid19_and_the_vasculature_current_aspects_and/09:48
BrainstormUpdates for Taiwan: +626 cases, +70573 tests since a day ago10:09
BrainstormNew from EMA: Human medicine assessment reports: (news): Human medicines European public assessment report (EPAR): HBVaxPro, hepatitis B vaccine (recombinant DNA), Hepatitis B;Immunization, Date of authorisation: 27/04/2001, Revision: 29, Status: Authorised → https://www.ema.europa.eu/en/medicines/human/EPAR/hbvaxpro10:18
BrainstormUpdates for Chiapas, Mexico: +117 cases since a day ago11:05
BrainstormNew from COVID on Twitter: Scott Gottlieb, MD (@ScottGottliebMD): Left: Shanghai lockdown protocolsRight: Translation twitter.com/sjoerddendaas/… → https://twitter.com/ScottGottliebMD/status/151381676221046784211:54
BrainstormNew from BMJ: Should we be clinically assessing antibody responses to covid vaccines in immunocompromised people?: The UK government has decreed that we must all now “live with covid.” All mandated isolation measures have ceased in England, free lateral flow testing for all has come to an end, and plans are in... → http://www.bmj.com/content/377/bmj.o966.short12:33
zutt%cases China12:48
Brainstormzutt: China has had 1.6 million confirmed cases (0.1% of all people) and 13465 deaths (0.8% of cases; 1 in 104116 people) as of 4 hours ago. 160.0 million tests were done (0.1 per capita, 1.0% positive). +26684 cases since 20 hours ago. See https://offloop.net/covid19/?default=China&legacy=no12:48
BrainstormNew from Pfizer: carterda: Myovant Sciences and Pfizer Provide Update on Supplemental New Drug Application for MYFEMBREE  for the Management of Moderate to Severe Pain Associated with Endometriosis → https://www.pfizer.com/news/press-release/press-release-detail/myovant-sciences-and-pfizer-provide-update-supplemental-new13:03
BrainstormUpdates for Bhutan: +2200 cases, +9619 tests since a day ago13:04
BrainstormNew from Politico: Breaches: Police float 30 more fines over UK government’s COVID rule-breaking parties → https://www.politico.eu/article/police-issue-50-fines-downing-street-whitehall-covid-parties/14:12
BrainstormNew from EMA: Human medicine assessment reports: (news): Human medicines European public assessment report (EPAR): Imvanex, smallpox vaccine (Live Modified Vaccinia Virus Ankara), Smallpox Vaccine, Date of authorisation: 31/07/2013, Revision: 20, Status: Authorised → https://www.ema.europa.eu/en/medicines/human/EPAR/imvanex14:22
BrainstormNew from Contagion Live: Text Messages Saying Influenza Vaccine ‘Reserved for You’ May Boost Uptake: Patients scheduled for primary care appointments were more likely to get an influenza vaccine if they received a text message the night before indicating one was [... want %more?] → https://www.contagionlive.com/view/text-messages-saying-influenza-vaccine-reserved-for-you-may-boost-uptake14:41
BrainstormNew from EMA: Human medicine assessment reports: (news): Human medicines European public assessment report (EPAR): RotaTeq, rotavirus vaccine, live, Immunization;Rotavirus Infections, Date of authorisation: 26/06/2006, Revision: 33, Status: Authorised → https://www.ema.europa.eu/en/medicines/human/EPAR/rotateq15:01
BrainstormNew from EMA: Human medicine assessment reports: (news): Human medicines European public assessment report (EPAR): Zostavax, shingles (herpes zoster) vaccine (live), Herpes Zoster;Immunization, Date of authorisation: 19/05/2006, Revision: 32, Status: Authorised → https://www.ema.europa.eu/en/medicines/human/EPAR/zostavax15:11
BrainstormNew from Politico: Breaches: Boris Johnson and Rishi Sunak to be fined for attending lockdown-breaking parties → https://www.politico.eu/article/uk-boris-johnson-and-rishi-sunak-to-be-fined-for-attending-covid19-breaking-parties/15:21
BrainstormNew from COVID on Twitter: Josiah 'So Mild' Grindrod (@JT_Grindrod): It was always impossible, y'all just didn't do 5 minutes of research on coronaviruses.theguardian.com/commentisfree/… → https://twitter.com/JT_Grindrod/status/151387857132396134616:00
BrainstormUpdates for Samoa: +427 cases, +2 deaths, +32653 tests since a day ago — Tonga: +115 cases, +2 deaths, +14506 tests since 23 hours ago16:06
BrainstormNew from COVID on Twitter: Tom Wenseleers (@TWenseleers): Other nice thread, pointing out that of the 2 mutations present in spike receptor binding domain of BA.4 & BA.5, L452R and F486V, F486V is in fact the one likely to lead to more antibody escape from serum elicited by current vaccines / earlier infections. [... want %more?] → https://twitter.com/TWenseleers/status/151388484594821530616:29
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol):   @ScienceTM How the Israeli booster campaign succeeded:Rapid response and"The vast benefits of vaccinating younger age groups that are not at a high risk of developing severe disease but play an important role in transmission."science.org/doi/10.1126/sc… [... want %more?] → https://twitter.com/EricTopol/status/151388799507779584216:38
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): Our covid times :-)by @MatttDavies pic.twitter.com/RvlIovr5nE → https://twitter.com/EricTopol/status/151389047660004967016:48
BrainstormNew from ClinicalTrials.gov: (news): Homologous vs Heterologous Third Vaccination in Kidney Transplant Recipients Kidney Transplant Recipients → https://clinicaltrials.gov/ct2/show/NCT0532431917:08
BrainstormNew from ClinicalTrials.gov: (translated) Neuropsychological Sequelae and Long COVID-19 Fatigue: Conditions: Anxiety Depression; Post Traumatic Stress Disorder; Mental Fatigue; COVID-19; Fatigue Syndrome, Chronic → https://clinicaltrials.gov/ct2/show/NCT0532331817:29
BrainstormNew from ClinicalTrials.gov: (news): Effectiveness and Tolerability of аgomelatine in the Treatment of Patients With Depression After COVID19 (TELESPHOR) → https://clinicaltrials.gov/ct2/show/NCT0532399417:39
BrainstormUpdates for Germany: +181728 cases, +217 deaths since 21 hours ago17:59
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): The US BA.2 wave —New cases up 17% in past week but no state is above 31/100,000 (Vermont)—Hospitalizations continue to decrease —~1 million PCR tests reported yesterday: 3.6% positivity—These are all encouraging metrics compared w/ what happened in many [... want %more?] → https://twitter.com/EricTopol/status/151391427987066880318:28
BrainstormNew from BBC Health: UK officials investigate 74 child hepatitis cases: One potential cause could be adenoviruses, but health experts are also looking at links to Covid-19. → https://www.bbc.co.uk/news/health-6108587018:37
BrainstormNew from Reddit (test): Covid2019: Covid Smell Loss Linked To Damage In Brain, Study Finds → https://old.reddit.com/r/Covid2019/comments/u234di/covid_smell_loss_linked_to_damage_in_brain_study/18:47
BrainstormNew from WebMD: NYC Mayor Tests Positive for COVID: New York City Mayor Eric Adams has tested positive for COVID-19 and is isolating while continuing to work. → https://www.webmd.com/lung/news/20220411/nyc-mayor-tests-positive-for-covid18:56
BrainstormUpdates for Italy: +84056 cases, +59 deaths, +563018 tests since 22 hours ago19:08
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): For protecting vs Omicron hospitalization, in people with prior Covid, the increase in vaccine effectiveness is approximately two-fold New @CDCMMWR cdc.gov/mmwr/volumes/7… pic.twitter.com/Ce2nXGYxeB → https://twitter.com/EricTopol/status/151393781801112371219:55
BrainstormUpdates for Greece: +15331 cases, +69 deaths, +334700 tests since a day ago — Spain: +34727 cases, +162 deaths since 3 days ago20:04
BrainstormNew from COVID on Twitter: Marc Veldhoen (@Marc_Veld): Population-level implications of the Israeli booster campaign to curtail COVID-19 resurgence"vast benefits of vaccinating younger age groups that are not at a high risk of developing severe disease but play an important role in transmission."science.org/doi/10.1126/sc… → https://twitter.com/Marc_Veld/status/151393958953845555820:05
BrainstormUpdates for Japan: +49474 cases, +47 deaths since 14 hours ago — Singapore: +4552 cases since 20 hours ago21:01
BrainstormNew from COVID on Twitter: NFID (@NFIDvaccines): 2022 #ACVR Highlights: 'Collaboration vs. competition—there is no space for competition during a pandemic' nfid.org/acvr @BIDMChealth @CDCgov @CEPIvaccines @florian_krammer @MountSinaiNYC @KayvonModjarrad pic.twitter.com/eITJTsoKOn → https://twitter.com/NFIDvaccines/status/151395146245129011221:03
BrainstormNew from Politico: Boris Johnson fined over lockdown breaches: What the hell happens now?: The British PM has apologized for the rule breach — how that goes down with his own MPs will determine his fate. → https://www.politico.eu/article/uk-prime-minister-boris-johnson-rishi-sunak-fined-lockdown-breaches-partygate-coronavirus-restrictions-sue-gray/21:22
BrainstormNew from r/COVID19: COVID19: Inhibition of the IFN-α JAK/STAT Pathway by MERS-CoV and SARS-CoV-1 Proteins in Human Epithelial Cells → https://old.reddit.com/r/COVID19/comments/u27gv7/inhibition_of_the_ifnα_jakstat_pathway_by_merscov/21:41
BrainstormNew from StatNews: Health: Covid vaccines didn’t work for many cancer patients — but researchers are designing a new shot for them → https://www.statnews.com/2022/04/12/new-covid-vaccine-being-developed-immunocompromised-people/22:01
BrainstormUpdates for France: +187020 cases, +157 deaths since 22 hours ago — Monaco: +67 cases since 22 hours ago22:09
BrainstormNew from CIDRAP: News Scan for Apr 12, 2022: COVID-19 and myocarditis COVID-related loss of smell More avian flu in the Dakotas → https://www.cidrap.umn.edu/news-perspective/2022/04/news-scan-apr-12-202222:11
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): The #SARSCoV2 spike protein-induced cell fusion activates the adaptive immunity interferon response, details here   @scisignal science.org/doi/10.1126/sc… pic.twitter.com/3CWX3dYDz8 → https://twitter.com/EricTopol/status/151397371879544832322:31
BrainstormNew from CIDRAP: Official closely track rising COVID levels in Northeastern states: Lisa Schnirring | News Editor | CIDRAP News Apr 12, 2022 Cases are rising in eastern states where BA.2 subvariant proportions are very high. Globally, COVID cases passed the [... want %more?] → https://www.cidrap.umn.edu/news-perspective/2022/04/official-closely-track-rising-covid-levels-northeastern-states22:41
BrainstormNew from WebMD: Philadelphia to Require Masks Again in Public Indoor Spaces: The city of Philadelphia reinstated its indoor face mask mandate on Monday, Citing an increase in COVID-19 cases because of the Omicron subvariant. → https://www.webmd.com/lung/news/20220412/philadelphia-to-require-masks-again-in-public-indoor-spaces22:50
BrainstormUpdates for United Kingdom: +38597 cases, +289 deaths since 22 hours ago — Canada: +11083 cases, +51 deaths since 19 hours ago23:00
qkall[m]Uhg I was really hoping this was coming to an end... I just want to go on vacation23:29
oerheksinfections seems to go down, due to less testing a lot of people think it is over.. deaths are about the same,, for NL at least23:33
BrainstormNew from WebMD: 2 New Omicron Subvariants Being Tracked: The World Health Organization is analyzing a few dozen cases of two new subvariants of the Omicron strain to determine how infectious and dangerous they might be. → https://www.webmd.com/lung/news/20220412/two-new-omicron-subvariants-being-tracked23:48

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