libera/##covid-19/ Monday, 2022-04-18

BrainstormNew from Reddit (test): nCoV: Major Japan firms shifting toward more recruitment and post-COVID growth | 17APR22 → https://old.reddit.com/r/nCoV/comments/u5x6qz/major_japan_firms_shifting_toward_more/00:11
TimvdeInteresting observation (but obviously n=1): one of the people I live with tested positive and now that her viral load is going down, it's clearly visible that when she samples her throat and her nose, the self tests work better00:50
Timvde(for the record: I tested negative, but even though she is isolated in her room and only comes out when necessary and with an FFP2, it's still in the house and I guess I should consider myself at risk)00:51
LjLTimvde, they work better when viral load goes *down*?00:51
TimvdeLjL: no, but it was just dark red when her viral load was high00:52
TimvdeNow the one where she also put the swab in her throat is clearly darker than the other one00:52
LjLi think it's puzzling this isn't discussed more, but Omicron has *got* to show up on rapid tests much, much more easily than Delta00:53
TimvdeLjL: assuming that the tests are equally effective at detecting omicron, yes, as the viral load is generally higher00:53
Timvdebut it can be negated by the test just being less effective for whatever reason, it's a different virus after all00:54
Timvde(not saying it is, just that the "has got" sounds a bit too strong)00:54
LjLTimvde, look at our antigen positive rate (right graph): https://lab24.ilsole24ore.com/coronavirus/#box_6a  zoom out so you see more/most of the pandemic, and you'll see until October or so, we had 1% positive *at best*, even though we had plenty positive on PCR ("molecolari")00:54
LjLbut now it's 15%00:54
LjLTimvde, i say "has got" based on these data, it's just staggering00:55
TimvdeLjL: now that's interesting00:55
TimvdeIt's also possible that people were doing more tests "to be sure" back then, while now they are doing them only when they have symptoms00:55
LjL(and sadly, it also shows us that while antigen prevalence is going down, PCR prevalence is going up :\)00:55
LjLTimvde, yes, but i'm not sure that justifies just a tremendous difference, also considering the difference was in full force back during "green pass for everything" era00:56
TimvdeI don't know enough Italian (~ none) to understand what that site says btw :P00:56
TimvdeOh, I think I found the graph00:57
LjLTimvde, i linked to the graph directly but sometimes it doesn't work00:57
TimvdeThat's antigen tests by a professional, right?00:57
LjLit's the one titled "Tamponi molecolari e antigenici"00:57
LjLTimvde, yes, self-tests aren't counted00:57
TimvdeYes, I found it00:57
BrainstormNew from BBC Health: Covid: Thousands of vaccinators get permanent NHS roles: The 11,483 people who have taken permanent NHS England jobs include former gym managers and air crew. → https://www.bbc.co.uk/news/health-6113528101:47
BrainstormNew from COVID on Twitter: Josiah 'So Mild' Grindrod (@JT_Grindrod): Yeah.. Our response to SARS eliminated my sliver of optimism that we'd ever get a handle on climate change. We can't take the slightest disruption to our day to day life, and dealing with climate change will require reworking our entire society.   [... want %more?] → https://twitter.com/JT_Grindrod/status/151585307294939546202:45
BrainstormNew from r/COVID19: COVID19: Efficacy and Safety of Fixed Combination of Hydroxychloroquine with Azithromycin Versus Hydroxychloroquine and Placebo in Patients with Mild COVID-19: Randomized, double blind, Placebo controlled trial → https://old.reddit.com/r/COVID19/comments/u60vn4/efficacy_and_safety_of_fixed_combination_of/03:04
BrainstormNew from Reddit (test): Covid2019: 4 Michiganders with COVID-19 strain unique to mink were likely 1st U.S. spillover cases → https://old.reddit.com/r/Covid2019/comments/u61o0x/4_michiganders_with_covid19_strain_unique_to_mink/04:29
BrainstormNew from r/Science: science: Vaccinated people over 65 with a history of substance abuse, mental health disorders including bipolar disorder, psychosis, and anxiety, have a 24% increased risk of contracting COVID-19. For those under 65, risks were up to 11% higher than for those [... want %more?] → https://old.reddit.com/r/science/comments/u63aq7/vaccinated_people_over_65_with_a_history_of/05:55
BrainstormNew from r/Science: science: New generation of cancer-preventing vaccines could wipe out tumors before they form | Science | AAAS → https://old.reddit.com/r/science/comments/u65ifg/new_generation_of_cancerpreventing_vaccines_could/07:42
BrainstormUpdates for Puerto Rico, United States: +4756 cases, +1 deaths since 3 days ago — Molise, Italy: +423 cases, +1 deaths since a day ago — Tatarstan, Russia: +247 cases, +4 deaths since a day ago — Zhejiang, China: +34 cases since a day ago08:11
BrainstormNew from Reddit (test): CoronavirusUK: Covid: Thousands of vaccinators get permanent NHS roles → https://old.reddit.com/r/CoronavirusUK/comments/u662mm/covid_thousands_of_vaccinators_get_permanent_nhs/08:20
BrainstormNew from COVID on Twitter: Michael Lin, MD PhD   (@michaelzlin): South Korea provides the first comparison of side effects across 5 vaccines using the same symptom tracker system. Minor error in that Supp Fig 1 and 2 captions are switched. twitter.com/pmcdunnough/st… → https://twitter.com/michaelzlin/status/151594568996810342508:59
BrainstormNew from Science-Based Medicine: Why is anyone surprised that there are so many antivax physicians?: A new survey suggests that a disturbingly high percentage of physicians are either vaccine hesitant or actually antivaccine. Those of us who have been writing about the [... want %more?] → https://sciencebasedmedicine.org/why-is-anyone-surprised-that-there-are-so-many-antivax-physicians/09:08
BrainstormUpdates for Taiwan: +1476 cases since a day ago10:03
BrainstormNew from r/COVID19: COVID19: Neurological sequela and disruption of neuron-glia homeostasis in SARS-CoV-2 infection → https://old.reddit.com/r/COVID19/comments/u68cxl/neurological_sequela_and_disruption_of_neuronglia/10:44
BrainstormNew from StatNews: Kizzmekia Corbett on the pandemic, public service, and her path to becoming a scientist: Kizzmekia Corbett, one of the designers of the Moderna Covid-19 vaccine, says everything that has gone into the pandemic response "just cannot be taken for granted." → https://www.statnews.com/2022/04/18/kizzmekia-corbett-scientist-pandemic/10:53
BrainstormNew from StatNews: Opinion: Men and women may respond differently to vaccines. Research needs to account for that: Tackling possible sex differences in the effects of new drugs and vaccines in humans should begin early on, in Petri dishes and animal studies. → https://www.statnews.com/2022/04/18/vaccine-research-sex-differences-into-consideration/11:03
BrainstormUpdates for Israel: +4528 cases since 20 hours ago12:09
BrainstormNew from ProPublica: Examining Nearly Two Decades of Taxpayer-Funded Border Operations: by Lomi Kriel and Perla Trevizo , ProPublica and The Texas Tribune , and Andrew Rodriguez Calderón , The Marshall Project ProPublica is a nonprofit newsroom that investigates [... want %more?] → https://www.propublica.org/article/examining-nearly-two-decades-of-taxpayer-funded-border-operations#131339112:18
zutt%cases china12:26
Brainstormzutt: China has had 1.8 million confirmed cases (0.1% of all people) and 13777 deaths (0.8% of cases; 1 in 101759 people) as of 4 hours ago. 160.0 million tests were done (0.1 per capita, 1.1% positive). +27634 cases, +32 deaths since 23 hours ago. See https://offloop.net/covid19/?default=China&legacy=no12:26
BrainstormNew from r/COVID19: COVID19: Development of antibody resistance in emerging mutant strains of SARS CoV-2: Impediment for COVID-19 vaccines → https://old.reddit.com/r/COVID19/comments/u69ont/development_of_antibody_resistance_in_emerging/12:38
BrainstormNew from r/Coronavirus: Coronavirus: Millions of Americans Have Long COVID. Exclusive Data Shows Which Patients Are Hit Hardest → https://old.reddit.com/r/Coronavirus/comments/u6a0p2/millions_of_americans_have_long_covid_exclusive/13:35
BrainstormNew from Reddit (test): nCoV: Global COVID Cases For 18APR22 → https://old.reddit.com/r/nCoV/comments/u6bb3b/global_covid_cases_for_18apr22/13:54
BrainstormNew from r/COVID19: Weekly Scientific Discussion Thread - April 18, 2022: This weekly thread is for scientific discussion pertaining to COVID-19. Please post questions about the science of this virus and disease here to collect them for others and clear up post space for [... want %more?] → https://old.reddit.com/r/COVID19/comments/u6bg3r/weekly_scientific_discussion_thread_april_18_2022/14:03
BrainstormNew from Reddit (test): nCoV: Clinical Catch-Up: AACR, AAN and COVID-19 | COVID-19-Related (first four items shown) | 18APR22 → https://old.reddit.com/r/nCoV/comments/u6c0ce/clinical_catchup_aacr_aan_and_covid19/14:33
BrainstormNew from Novavax: (news): Novavax Grows Presence at World Vaccine Congress and 32nd European Congress of Clinical Microbiology & Infectious Diseases → https://ir.novavax.com/2022-04-18-Novavax-Grows-Presence-at-World-Vaccine-Congress-and-32nd-European-Congress-of-Clinical-Microbiology-Infectious-Diseases15:41
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): Covid shouldn't even be in the top 10 causes of death in the US if we consistently used all the tools available. Yet we're still now losing the lives of 500 Americans each day. pic.twitter.com/1la3Qx75vk → https://twitter.com/EricTopol/status/151606618991450112416:58
BrainstormUpdates for Marshall Is.: +7 cases since 2 months ago17:03
BrainstormNew from Contagion Live: us: Age and Comorbidity Predict COVID-19 Death More Accurately Than Innate Immune Response → https://www.contagionlive.com/view/age-and-comorbidity-predict-covid-19-death-more-accurately-than-innate-immune-response17:17
BrainstormNew from BMJ Open: Prevalence and predictors of influenza vaccination in long-term care homes: a cross-national retrospective observational study: Objective To compare facility-level influenza vaccination rates in long-term care (LTC) homes from four countries and to identify factors associated with influenza [... want %more?] → http://bmjopen.bmj.com/cgi/content/short/12/4/e05751717:56
BrainstormUpdates for Germany: +18010 cases, +9 deaths since 23 hours ago18:00
BrainstormNew from Virological.org: Latest posts: Rapid Establishment of Omicron Variant in Rio Grande do Sul State, Brazil: Update Information - The finding of a new Omicron-L452R mutant in Southern Brazil SARS-CoV-2 Omicron variant (B.1.1.529) established in a short period [... want %more?] → https://virological.org/t/rapid-establishment-of-omicron-variant-in-rio-grande-do-sul-state-brazil/783#post_318:06
BrainstormNew from CIDRAP: RDSP maps medicine supply to US to predict, prevent shortages (part 2 of 2): Mary Van Beusekom | News Writer | CIDRAP News Apr 18, 2022 "When prescription drugs are not affordable or accessible for any reason, consumers can experience lost [... want %more?] → https://www.cidrap.umn.edu/news-perspective/2022/04/rdsp-maps-medicine-supply-us-predict-prevent-shortages-part-2-218:36
BrainstormNew from COVID on Twitter: Michael Lin, MD PhD   (@michaelzlin): Age could affect symptomaticity and willingness to report.I believe Pfizer and AZ were available first, so older ages are likely more represented.Note queried symptoms are fewest for Pfizer and AZ, and longest for Novavax, corresponding to when [... want %more?] → https://twitter.com/michaelzlin/status/151609726593647001718:56
BrainstormUpdates for Canada: +10114 cases, +21 deaths since 20 hours ago19:08
BrainstormNew from COVID on Twitter: Dr Emma Hodcroft (@firefoxx66): Tune in next week for a great panel discussion to celebrate #DayofImmunology moderated by @apoorva_nyc & including myself, @florian_krammer, Mohamed Ridha Barbouche & Herbert "Skip" Virgin, about virus evolution, vaccines, & what it might mean for the [... want %more?] → https://twitter.com/firefoxx66/status/151610371274941644919:25
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): An in-depth review for the reason for Omicron wave (BA.1, BA 1.1, BA.2) hospitalizations at a leading tertiary center @erasmusuni @erasmusMC66% were attributable to Covid (not incidental "with")medrxiv.org/content/10.110… → https://twitter.com/EricTopol/status/151611389211556249620:04
BrainstormUpdates for Italy: +18588 cases, +79 deaths, +105739 tests since a day ago20:11
BrainstormNew from StatNews: Federal judge voids U.S. mask mandate for planes, other travel: A federal judge in Florida has voided the national mask mandate covering airplanes and other public transportation as exceeding the authority of U.S. health officials in the coronavirus pandemic. → https://www.statnews.com/2022/04/18/federal-judge-voids-us-mask-mandate-for-planes-other-travel/20:33
BrainstormNew from Reddit (test): Covid2019: Long-term lung abnormalities common 1 year after COVID-19 pneumonia → https://old.reddit.com/r/Covid2019/comments/u6k8hb/longterm_lung_abnormalities_common_1_year_after/20:42
BrainstormNew from Reddit (test): Covid2019: Immunocompromised patients ‘continue to battle’ as COVID-19 restrictions ease: Medical-grade masks — N95 or KN95 — remain the gold standard, while avoiding crowded indoor gatherings and social distancing can go even further in [... want %more?] → https://old.reddit.com/r/Covid2019/comments/u6keqn/immunocompromised_patients_continue_to_battle_as/20:53
BrainstormNew from COVID on Twitter: Josiah 'So Mild' Grindrod (@JT_Grindrod): Anti-Vaxxers: "everyone who got the v4xx will be dead in 6 months! And if they don't die they'll have AIDS!"ZeroCovid advocates: "vaccines are an important layer of protection but alone don't do enough to slow spread"Twitter "experts": "These [... want %more?] → https://twitter.com/JT_Grindrod/status/151612759395037184121:03
BrainstormNew from Reddit (test): nCoV: Shanghai Reports First Deaths from Omicron Outbreak → https://old.reddit.com/r/nCoV/comments/u6lt5k/shanghai_reports_first_deaths_from_omicron/22:01
BrainstormUpdates for France: +19810 cases, +48 deaths since a day ago — Canada: +10470 cases since 23 hours ago22:10
BrainstormNew from COVID on Twitter: Florian Krammer (@florian_krammer): Interesting findings regarding anti-formulation/anti-PEG antibodies induced by mRNA-1273 versus BNT162b2 led by Juan Manuel Carreño and @gabagagan in my lab. medrxiv.org/content/10.110… → https://twitter.com/florian_krammer/status/151614551237369856522:11
BrainstormNew from COVID on Twitter: Trevor Bedford (@trvrb): However, it's also possible for some other mutational constellation to arise (on top of BA.2 or otherwise) and overtake these new 452R/Q lineages. 16/17twitter.com/trvrb/status/1… → https://twitter.com/trvrb/status/151614753352903884922:21
BrainstormNew from COVID on Twitter: Trevor Bedford (@trvrb): This sort of accumulation of mutations that drive further host adaptation and antigenic drift is my general expectation for evolution in the coming months. It's possible we may have additional "Omicron-like" events, but my baseline is this steady "flu-like" scenario. 17/17 → https://twitter.com/trvrb/status/151614753514805248022:31
BrainstormNew from COVID on Twitter: Trevor Bedford (@trvrb): @jbloom_lab Excellent point. Do you know when we might expect to have experiments with L452R/Q viruses tested against post-infection sera from individuals recovered from Omicron? → https://twitter.com/trvrb/status/151615293053712793622:41
BrainstormNew from CIDRAP: Global data reveal half may have long COVID 4 months on: Mary Van Beusekom | News Writer | CIDRAP News Apr 18, 2022 Review of 31 studies finds fatigue, memory problems, and shortness of breath are most common. → https://www.cidrap.umn.edu/news-perspective/2022/04/global-data-reveal-half-may-have-long-covid-4-months23:10
BrainstormNew from COVID19 Vaccine Tracker: (translated) valerie: AnGes: AG0302-COVID19 → https://covid19.trackvaccines.org/vaccines/31/23:20
BrainstormNew from COVID19 Vaccine Tracker: valerie: AIM Vaccine: LVRNA009 → https://covid19.trackvaccines.org/vaccines/189/23:30
BrainstormNew from COVID19 Vaccine Tracker: valerie: Airlangga University: UNAIR Inactivated COVID-19 Vaccine → https://covid19.trackvaccines.org/vaccines/181/23:39
BrainstormNew from COVID19 Vaccine Tracker: (translated) valerie: AnGes: AG0301-COVID19 → https://covid19.trackvaccines.org/vaccines/3/23:49
BrainstormNew from COVID19 Vaccine Tracker: valerie: Arcturus Therapeutics Inc: ARCT-154 → https://covid19.trackvaccines.org/vaccines/140/23:59

Generated by irclog2html.py 2.17.0 by Marius Gedminas - find it at https://mg.pov.lt/irclog2html/!