libera/##covid-19/ Wednesday, 2022-04-27

BrainstormUpdates for United Kingdom: +16848 cases, +452 deaths since 21 hours ago00:05
BrainstormNew from Ars Technica: Science: US failed miserably at protecting children from omicron, CDC study finds → https://arstechnica.com/?p=185064100:39
BrainstormUpdates for South Africa: +5062 cases, +15 deaths, +37626 tests since a day ago — India: +3569 cases since 23 hours ago — Trinidad and Tobago: +576 cases, +1 deaths since a day ago — Germany: +135699 cases, +307 deaths since 23 hours ago01:01
BrainstormNew from r/COVID19: COVID19: About 30% of COVID patients develop “Long COVID,” UCLA research finds → https://old.reddit.com/r/COVID19/comments/ucp9js/about_30_of_covid_patients_develop_long_covid/01:38
BrainstormNew from COVID on Twitter: Michael Lin, MD PhD   (@michaelzlin): Novavax had a minor update at ECCMIDThe NVX vaccine showed VE = 76% against asymptomatic infection during its UK trial (mostly Alpha). They point out this is higher than reported for other vaccines (refs in image 2). pic.twitter.com/3OURnrHTuW → https://twitter.com/michaelzlin/status/151909786218905190401:47
BrainstormNew from COVID on Twitter: Michael Lin, MD PhD   (@michaelzlin): But following up on the refs,Sahly NEJM 2021 is Moderna: 63% (95% CI = 57 to 69%)Sadoff Lancet 2021 is J&J: 66% (95% CI = 40 to 81%)Voysey Lancet 2021 is AZ: 27% (95% CI = -17 to 55%)Novavax is 76% with 95% CI = 57 to 87% so not clearly different [... want %more?] → https://twitter.com/michaelzlin/status/151910242297874432001:57
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): The potent immune response induced by a 3rd dose vaccine vs Omicron BA.1, BA.1.1, and BA.2 variantscell.com/med/fulltext/S…   @MedCellPress in 272 health care workers pic.twitter.com/p2bHpgC0aU → https://twitter.com/EricTopol/status/151910803480652595802:26
BrainstormUpdates for Samoa: +1166 cases, +3 deaths, +5815 tests since 3 days ago — Canada: +17099 cases, +87167 tests since 20 hours ago03:00
de-facto%title https://www.researchsquare.com/article/rs-1582065/v103:12
Brainstormde-facto: From www.researchsquare.com: Cortical Grey Matter Volume Loss links to Neurological Sequelae in post COVID-19 “Long Haulers” | Research Square03:12
LjLfrightening :(03:38
de-factomaybe politicians removing rules for mandatory mask indoors should be forced to read such studies03:58
de-factoand publicly sign a legally binding statement that they read it and had the opportunity to consult experts on unclear points03:59
BrainstormUpdates for Australia: +38440 cases, +56 deaths since 23 hours ago — Barbados: +506 cases, +2748 tests since a day ago — United Kingdom: +16846 cases since 23 hours ago04:09
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): "China's biggest Covid failure"bloomberg.com/news/articles/… twitter.com/EricTopol/stat… pic.twitter.com/dIadZGH08A → https://twitter.com/EricTopol/status/151913506681056870504:12
de-facto%title https://www.reuters.com/business/healthcare-pharmaceuticals/china-reports-first-human-case-h3n8-bird-flu-2022-04-26/04:26
Brainstormde-facto: From www.reuters.com: China reports first human case of H3N8 bird flu | Reuters04:26
de-facto%title https://www.scmp.com/news/china/science/article/3175626/china-boy-becomes-first-recorded-human-case-h3n8-bird-flu-strain04:39
Brainstormde-facto: From www.scmp.com: Boy in China becomes first recorded human case of H3N8 bird flu strain | South China Morning Post04:39
de-facto%title http://www.nhc.gov.cn/yjb/s3578/202204/8dbeadf0efed45b0b2ea22928523e289.shtml04:45
Brainstormde-facto, the URL could not be loaded04:45
de-factohttps://www-nhc-gov-cn.translate.goog/yjb/s3578/202204/8dbeadf0efed45b0b2ea22928523e289.shtml?_x_tr_sch=http&_x_tr_sl=auto&_x_tr_tl=en&_x_tr_hl=en-US&_x_tr_pto=wapp04:45
BrainstormNew from r/Coronavirus: Coronavirus: At least a dozen U.S. universities reinstate mask mandates as Covid cases rise → https://old.reddit.com/r/Coronavirus/comments/ucsuye/at_least_a_dozen_us_universities_reinstate_mask/04:51
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): 60,000 new cases reported today and over 400 new hospitalizations and it's still early as the US transitions to the BA.2.12.1 variant wavenewsnodes.com/us twitter.com/EricTopol/stat… → https://twitter.com/EricTopol/status/151914821467013529605:01
BrainstormNew from ScienceNews: Antibiotics diminish babies’ immune response to key vaccines: With each round of antibiotics during a child’s first two years, antibody levels to four vaccines dropped further from what’s considered protective. → https://www.sciencenews.org/article/antibiotics-babies-immune-response-vaccines-gut-bacteria06:09
DescartesWhat percentage of people who get a corona virus infection become long haulers?06:20
Descarteshttps://www.researchsquare.com/article/rs-1582065/v106:21
BrainstormNew from r/COVID19: COVID19: Effectiveness of a second BNT162b2 booster vaccine against hospitalization and death from COVID-19 in adults aged over 60 years → https://old.reddit.com/r/COVID19/comments/ucv99v/effectiveness_of_a_second_bnt162b2_booster/06:47
Descarteshttps://www.nytimes.com/2022/04/19/us/politics/moderna-vaccine-beta-variant.html06:52
DescartesModerna says trial results suggest redesigned vaccines can better protect against variants.06:52
DescartesResearchers combined Moderna’s existing vaccine with one designed to attack the Beta variant, and found it provided a stronger defense against several variants.06:52
DescartesModerna said its research showed the promise of a so-called bivalent vaccine, even against other variants besides the two versions of the virus specifically targeted. In this case, researchers combined the existing vaccine with one designed to attack the Beta variant, which was first detected in late 2020. They found the combination provided a stronger defense not only against those forms of...06:54
Descartes...the virus, but also against the Delta and Omicron variants, the company said.06:54
DescartesBy Sharon LaFraniere, April 19, 2022, New York Times06:55
Descarteshttps://www.researchsquare.com/article/rs-1555201/v106:56
DescartesSafety, Immunogenicity and Antibody Persistence of a Bivalent Beta-Containing Booster Vaccine06:56
Descartesposted 15 Apr, 202206:57
DescartesIf Moderna's published results prove to be so effective in further studies, and are confirmed by other researchers, when will these redesigned vaccines become available in North America?07:01
BrainstormUpdates for Switzerland: +17109 cases since 14 hours ago07:05
BrainstormNew from r/Science: science: Vaccine-derived polio is on the upswing. Can a new vaccine stop the spread → https://old.reddit.com/r/science/comments/ucvayq/vaccinederived_polio_is_on_the_upswing_can_a_new/07:26
BrainstormUpdates for Victoria, Australia: +10420 cases, +30 deaths since a day ago — Osaka, Japan: +3966 cases, +12 deaths since a day ago — Goias, Brazil: +2815 cases, +6 deaths since a day ago — Aichi, Japan: +2772 cases, +2 deaths since a day ago08:01
BrainstormNew from r/Coronavirus: Daily Discussion Thread | April 27, 2022: Please refer to our Wiki for more information on COVID-19 and our sub. You can find answers to frequently asked questions in our FAQ , where there is valuable information such as our: → https://old.reddit.com/r/Coronavirus/comments/ucxjz8/daily_discussion_thread_april_27_2022/09:05
BrainstormUpdates for Germany: +141661 cases since 15 hours ago09:10
BrainstormNew from Politico: German consumer pessimism deepens: survey: FRANKFURT – Consumer confidence in Germany deteriorated significantly in April to plunge well below a previous record set in spring 2020 during the first pandemic lockdown, a key survey showed Wednesday. According to the GfK consumer [... want %more?] → https://www.politico.eu/article/german-consumer-pessimism-deepens-survey/09:25
BrainstormUpdates for Taiwan: +8916 cases, +2 deaths, +92756 tests since 23 hours ago10:01
BrainstormNew from COVID on Twitter: Gunhild Alvik Nyborg (@GANyborg): So what’s the problem w official   reports stating that if we only had higher ICU capacity, we wouldn’t have had to lock down? They haven’t done the calculations. “'Shielding' strategies instead of lockdowns would have led to tens of thousands more [... want %more?] → https://twitter.com/GANyborg/status/151922565890330214410:16
BrainstormNew from COVID on Twitter: Gunhild Alvik Nyborg (@GANyborg): The study finds that even in the highly unrealistic scenario of perfect shielding,“ICU bed capacity in England would have been exceeded by over a factor of 10 at the peak of the epidemic” & about 50,000 lives among low-risk individuals would’ve been [... want %more?] → https://twitter.com/GANyborg/status/151922926020825907210:26
BrainstormNew from COVID on Twitter: Tom Wenseleers (@TWenseleers): @Tuliodna @GISAID @nicd_sa @SACEMAdirector @jburnmurdoch Quick reminder also about the @GISAID terms of use. PS: was the >3 million SARS-CoV2 genomes submitted by @CovidGenomicsUK and the >10 million genomes submitted by the global north not a fantastic [... want %more?] → https://twitter.com/TWenseleers/status/151923294573889126610:36
BrainstormNew from Politico: Brexit caused food price hike in the UK, report says: Coronavirus pandemic not to blame for 6 percent increase, according to research. → https://www.politico.eu/article/uk-research-food-prices-hike-report-brexit-cost-living/10:57
BrainstormNew from Reddit (test): CoronaVirus_2019_nCoV: Know your variants: A coronavirus 'cheat sheet' → https://old.reddit.com/r/CoronaVirus_2019_nCoV/comments/ucz6os/know_your_variants_a_coronavirus_cheat_sheet/11:08
BrainstormNew from BMJ: Parosmia—a common consequence of covid-19: What you need to knowParosmia is a common sequelae of smell loss associated with covid-19, with onset on average three months after initial infectionRefer patients with parosmia without a clear... → http://www.bmj.com/content/377/bmj-2021-069860.short11:28
BrainstormNew from COVID on Twitter: Marc Veldhoen (@Marc_Veld): Three-dose vaccination increased anti-Spike antibody and NTs against Omicron variants.Immunogenicity against Omicron subvariants did not change after three-dose vaccination.The cytokine signature remained unchanged after three-dose vaccination. pic.twitter.com/gLrlexp45U → https://twitter.com/Marc_Veld/status/151925144999321600011:48
BrainstormNew from ProPublica: Reality Check: Seven Times Texas Leaders Misled the Public About Operation Lone Star: by Perla Trevizo and Lomi Kriel , ProPublica and The Texas Tribune , Kengo Tsutsumi , ProPublica, and Andrew Rodriguez Calderón , The Marshall Project ProPublica is a nonprofit newsroom [... want %more?] → https://www.propublica.org/article/texas-greg-abbott-border-crisis-facts#131992512:09
BrainstormNew from COVID on Twitter: Squawk Box (@SquawkCNBC): "They are behind schedule on trying to deploy vaccines that are going to be effective against these new variants," says @ScottGottliebMD on China. "This is probably going to be perpetual until they are able to get ahead of the curve and deploy vaccines that are [... want %more?] → https://twitter.com/SquawkCNBC/status/151926406101124300812:49
BrainstormNew from Pfizer: Anonymous: Pfizer and Biohaven’s VYDURA  (Rimegepant) Granted First Ever Marketing Authorization by European Commission for Both Acute Treatment of Migraine and Prophylaxis of Episodic Migraine → https://www.pfizer.com/news/press-release/press-release-detail/pfizer-and-biohavens-vydurar-rimegepant-granted-first-ever12:59
BrainstormNew from WebMD: Personal Essay: I Started Transitioning at the Beginning of the Pandemic. Here’s What It Was Like: Two years ago, just when the world was shutting down, I opened up – to my true self. Having discovered that I was a transgender man, I set out to medically transition at the onset of the pandemic. → https://www.webmd.com/sex/features/allen-juneau-personal-essay13:19
BrainstormNew from COVID on Twitter: Tulio de Oliveira (@Tuliodna): Our team ended working most of the holiday in South Africa to help to characterize the BA.4 and BA.5 lineages of Omicron. But I managed to have a lunch break and go with family to a beautiful setting close by! Happy freedom day in South African as I now go back [... want %more?] → https://twitter.com/Tuliodna/status/151929184171945984014:34
BrainstormNew from BBC Health: Covid: Discharging hospital patients to care homes 'unlawful': The High Court says government policies did not take into account transmission risks to the elderly. → https://www.bbc.co.uk/news/uk-england-6122770914:44
BrainstormNew from Politico: EU ends emergency phase of coronavirus pandemic: While the pandemic is still with us, it's time to shift out of crisis mode, says health commissioner. → https://www.politico.eu/article/eu-ends-emergency-phase-of-coronavirus-pandemic/15:04
BrainstormNew from COVID on Twitter: Scott Gottlieb, MD (@ScottGottliebMD): COVID mitigation in China.This is not a sustainable strategy. twitter.com/danmurtaugh/st… → https://twitter.com/ScottGottliebMD/status/151930547936059392315:25
BrainstormUpdates for Belarus: +656 cases, +5 deaths, +12535 tests since 23 hours ago — Canada: +9266 cases, +61 deaths since 23 hours ago16:04
BrainstormNew from COVID on Twitter: Yale Center for Infection and Immunity (@YaleCII): We are now live @YaleCII! Please visit our website medicine.yale.edu/cii/ and find out about our goals, research plans, and members working together to better understand infectious diseases and their link to chronic diseases, and to develop [... want %more?] → https://twitter.com/YaleCII/status/151931197417733324816:06
BrainstormNew from r/COVID19: COVID19: Anti-SARS-Cov-2 S-RBD IgG formed after BNT162b2 vaccination can bind C1q and activate complement → https://old.reddit.com/r/COVID19/comments/ud49pc/antisarscov2_srbd_igg_formed_after_bnt162b2/16:16
BrainstormNew from r/COVID19: COVID19: A cocktail containing two synergetic antibodies broadly neutralizes SARS-CoV-2 and its variants including Omicron BA.1 and BA.2 → https://old.reddit.com/r/COVID19/comments/ud4bk5/a_cocktail_containing_two_synergetic_antibodies/16:26
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): Why is Puerto Rico at 100 new cases/100K residents, by far the highest for the US, but New York, with dominant B.2.12.1 (and its L452Q mutation), at 33/100K?Likely contributor:Seroprevalence Puerto Rico 37% vs NY 62% at end February [... want %more?] → https://twitter.com/EricTopol/status/151932734201902694416:55
BrainstormUpdates for Greece: +11487 cases, +46 deaths since a day ago17:01
BrainstormNew from ClinicalTrials.gov: (news): Impact of Covid-19 on Rhinovirus Epidemic → https://clinicaltrials.gov/ct2/show/NCT0534870717:05
BrainstormNew from ClinicalTrials.gov: (news): Impact of the Covid-19 on RSV Epidemic in the Metropolis of Lyon → https://clinicaltrials.gov/ct2/show/NCT0534865517:15
BrainstormNew from LitCovid: (news): Correspondence on "Herpes Zoster and Simplex reactivation following COVID-19 vaccination". → https://www.ncbi.nlm.nih.gov/research/coronavirus/publication/3547114317:25
BrainstormNew from ClinicalTrials.gov: Impact of the Covid-19 on RSV: Conditions :    Rhinovirus;   RSV Infection in Infants Less Than 1 Years of Age → https://clinicaltrials.gov/ct2/show/NCT0534861617:35
BrainstormUpdates for Germany: +205 deaths since 17 hours ago18:03
BrainstormNew from COVID on Twitter: Gunhild Alvik Nyborg (@GANyborg): To add: it's been shown that it is impossible to "protect the vulnerable". "Due to synchronization effects, we find that maintaining a slower epidemic growth behaviour for the high-risk group is unstable against any finite coupling between the two groups" [... want %more?] → https://twitter.com/GANyborg/status/151934991116208128018:25
BrainstormNew from University of Washington: UW Custodians' Daughter Leads Effort to Recognize Forgotten Set of Workers: Evalynn Romano Close Portrait by Anil Kapahi View image caption Custodial workers have served diligently during the pandemic. Department of [... want %more?] → https://globalhealth.washington.edu/news/2022/04/27/uw-custodians-daughter-leads-effort-recognize-forgotten-set-workers18:45
BrainstormNew from COVID on Twitter: Marc Veldhoen (@Marc_Veld): An orally available Mpro inhibitor is effective against wild-type SARS-CoV-2 and variants including Omicronpromising new drug: but still at preclinical (mouse) stage. The pandemic has much boosted drug-research against viral infections.nature.com/articles/s4156… → https://twitter.com/Marc_Veld/status/151935730147548774418:55
BrainstormUpdates for Canada: +10007 cases, +34 deaths since 23 hours ago19:06
BrainstormNew from WebMD: Smart Toilets: Next Tool Against Diseases (Including COVID): Human stool contains a treasure trove of valuable health information. New tech-enabled toilets offer a way to capture key insights before they’re flushed away. → https://www.webmd.com/digestive-disorders/news/20220427/smart-toilets-next-tool-against-diseases-including-covid19:24
BrainstormUpdates for Italy: +88431 cases, +186 deaths, +554526 tests since a day ago — Japan: +42232 cases, +60 deaths since 12 hours ago — United Kingdom: +17206 cases, +304 deaths since 19 hours ago20:02
BrainstormNew from COVID on Twitter: Michael Lin, MD PhD   (@michaelzlin): One of the NS3 inhibitors, boceprevir, was found by us, other labs, and Merck (and probably Pfizer too) to work on SARSCoV2 protease. Other than Merck, all of these groups then modified it for better activity against SARSCoV2. That's how Paxlovid was [... want %more?] → https://twitter.com/michaelzlin/status/151937703643480473620:10
BrainstormNew from COVID on Twitter: (translated) Gunhild Alvik Nyborg (@GANyborg): Unfortunately, this was far too predictable. @NAVnorge lacks correct knowledge and understanding of Long Covid. And so does @Folkehelseinst and, it seems. And many other professionals.This can be very heavy for many, I'm afraid.nrk.no/norge/ni-av-ti… → https://twitter.com/GANyborg/status/151938213145733940120:30
BrainstormNew from CIDRAP: News Scan for Apr 27, 2022: DRC Ebola vaccine launch Third vaccine dose and Omicron Measles uptick Canada probes unexplained hepatitis cases USDA boosts avian flu funding → https://www.cidrap.umn.edu/news-perspective/2022/04/news-scan-apr-27-202221:21
BrainstormNew from Contagion Live: Do Age and Gender Affect Immune Response to COVID-19 Vaccination?: A recent study examined whether immune response to the Pfizer-BioNTech COVID-19 vaccine differed by age and gender. → https://www.contagionlive.com/view/do-age-and-gender-affect-immune-response-to-covid-19-vaccination-21:31
BrainstormNew from StatNews: Covid’s circling the White House. What are the risks to someone like Biden?: When President Trump became infected with Covid in October 2020, he had to be airlifted to Walter Reed Medical Center for treatment. If Biden, who is 79, were to become… → https://www.statnews.com/2022/04/27/covid-risks-president-biden-white-house/21:56
BrainstormUpdates for France: +67797 cases, +152 deaths since a day ago22:02
BrainstormNew from WebMD: Unvaccinated People Create Higher Risk for Vaccinated, Study Says: People who don’t get vaccinated against COVID-19 are creating a “disproportionate” threat to the health of vaccinated people, even in places with high [... want %more?] → https://www.webmd.com/vaccines/covid-19-vaccine/news/20220427/unvaccinated-people-create-higher-risk-for-vaccinated-study-says22:23
BrainstormNew from COVID on Twitter: Michael Lin, MD PhD   (@michaelzlin): We've all heard: Fauci says FDA slow-walking Moderna to let Pfizer catch up to "not confuse people"FDA isn't noticeably improving under Califf. If anything it seems to be retrenching to its pre-pandemic SOP of "if in doubt, delay"arstechnica.com/science/2022/0… → https://twitter.com/michaelzlin/status/151942956389318246423:42
BrainstormNew from COVID on Twitter: Michael Lin, MD PhD   (@michaelzlin): And finally the 44% VE of Moderna against Omicron disease is better than 1xJJ or 2xJJ in adults, both of which are still approved. And the 50% threshold is arbitrary anyway, while we have every reason to believe 44% VE will correlate with higher VE [... want %more?] → https://twitter.com/michaelzlin/status/151943293975429529623:51

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