libera/##covid-19/ Thursday, 2022-04-28

BrainstormUpdates for Brazil: +20943 cases, +147 deaths since 22 hours ago — South Africa: +6371 cases, +3 deaths since 22 hours ago — Eswatini: +102 cases, +430 tests since 23 hours ago00:01
BrainstormNew from COVID on Twitter: Michael Lin, MD PhD   (@michaelzlin): FDA has learned nothing from the pandemic. They're still enslaved to arbitrary numbers such as 50% VE and 95% confidence. Sure, in nonemergency times you can decide on a standard and stick to it. But we are in a 100-year flood here; we should use [... want %more?] → https://twitter.com/michaelzlin/status/151943294170045235200:01
BrainstormNew from COVID on Twitter: Marc Veldhoen (@Marc_Veld): ICU admission and deaths pic.twitter.com/94rLlJd1Up → https://twitter.com/Marc_Veld/status/151943833012716748800:12
BrainstormNew from The Lancet (Online): [Comment] Optimising child and adolescent health and development in the post-pandemic world: Our Series on optimising child and adolescent health and development follows on almost two decades after the original Lancet Series on child survival and its [... want %more?] → https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(21)02789-6/fulltext00:32
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): Analysis of over 30 million US Covid cases and 440,00 deaths in >2500 counties: For every 10% improvement in vaccination coverage *per county*, there was an 8% reduction in mortality bmj.com/content/377/bm…  @bmj_latest documenting the community level benefit vs [... want %more?] → https://twitter.com/EricTopol/status/151944784976681779300:52
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): Paper and accompanying editorial bmj.com/content/377/bm…"Many more lives could have been saved......this new study is another confidence booster for covid-19 vaccines." pic.twitter.com/o4FygrAX8T → https://twitter.com/EricTopol/status/151945015498146611301:02
BrainstormUpdates for Germany: +9187 cases, +245 deaths since 15 hours ago01:10
BrainstormNew from r/COVID19: COVID19: An open label randomized clinical trial of Indomethacin for mild and moderate hospitalised Covid-19 patients → https://old.reddit.com/r/COVID19/comments/udh1sn/an_open_label_randomized_clinical_trial_of/01:50
BrainstormUpdates for Canada: +13085 cases, +110 deaths since 22 hours ago02:00
BrainstormUpdates for Slovakia: +3759 cases since 15 hours ago — Micronesia: +2 cases since a day ago03:03
BrainstormNew from COVID on Twitter: Josiah 'So Mild' Grindrod (@JT_Grindrod): We've known that SARS Coronaviruses can cause hepatitis since 2004. There is no mystery here, just    → https://twitter.com/JT_Grindrod/status/151949133980873932803:48
BrainstormUpdates for Australia: +45967 cases, +50 deaths since 23 hours ago — United Kingdom: +17879 cases since 23 hours ago03:59
BrainstormNew from COVID on Twitter: Michael Lin, MD PhD   (@michaelzlin): Topol is always eager to declare mission accomplished. It's really too early in Taiwan's surge to say there are no deaths. And since only 70% over 75yo are vaxxed, if Omicron continues to surge, I think there will be some deaths unfortunately. [... want %more?] → https://twitter.com/michaelzlin/status/151949756657602150404:07
BrainstormNew from COVID on Twitter: Michael Lin, MD PhD   (@michaelzlin): NO. Taiwan is not an "archetype of decoupling." Taiwan has only vaccinated ~70% of those over 75yo. Maybe higher in recent weeks, but not yet high enough.The tweet below is wrong and irresponsible. Surge is still early and smal. Deaths follow by [... want %more?] → https://twitter.com/michaelzlin/status/151951002390636134404:56
BrainstormNew from COVID on Twitter: Michael Lin, MD PhD   (@michaelzlin): So to my extended family of 23M Taiwanese: Topol's post says nothing useful. In fact it's harmful. Taiwan is not likely to be an archetype of uncoupling if Omicron surges more.Get your family members vaccinated now, if they haven't already, [... want %more?] → https://twitter.com/michaelzlin/status/151951194843751219305:06
BrainstormNew from COVID on Twitter: Michael Lin, MD PhD   (@michaelzlin): Earlier this month only 71% of people >75yo in Taiwan had their second vax shot. Only 56% had 3. That's worse than US before Omicron hit, and, lest we forget, US saw 3000 deaths a day during Omicron.twitter.com/dshihlai/statu… → https://twitter.com/michaelzlin/status/151951457052352102405:15
BrainstormNew from COVID on Twitter: Michael Lin, MD PhD   (@michaelzlin): So to my extended family of 23M Taiwanese: Topol's post is wrong and harmful. Taiwan is facing disaster if Omicron surges faster than vaccination.Get your family members vaccinated now, if they haven't already, especially the older ones.Please retweet! → https://twitter.com/michaelzlin/status/151951627276079104205:25
BrainstormNew from Reddit (test): Covid2019: Scientists have found misinformation posted online about the COVID-19 vaccine was associated with hesitancy toward inoculation and lower vaccination rates in some geographical areas of the United States → https://old.reddit.com/r/Covid2019/comments/udlnp6/scientists_have_found_misinformation_posted/05:35
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): What about the BA.2 wave in the US?98,000 confirmed new cases, and > 500 added hospitalizations reported todaynewsnodes.com/us → https://twitter.com/EricTopol/status/151952000799405260905:44
BrainstormNew from Reddit (test): Covid2019: 'We're in another wave': Wastewater dats shows how fast COVID is spreading across Bay Area - "The concentrations right now are similar to what they were during the delta surge back in the summer of 2021," → https://old.reddit.com/r/Covid2019/comments/udm6e6/were_in_another_wave_wastewater_dats_shows_how/06:03
BrainstormUpdates for Germany: +130104 cases since 21 hours ago06:11
BrainstormNew from Reddit (test): CoronaVirus_2019_nCoV: SF clinic gearing up as FDA gets closer to authorizing vaccine for kids under 5 → https://old.reddit.com/r/CoronaVirus_2019_nCoV/comments/udmfri/sf_clinic_gearing_up_as_fda_gets_closer_to/06:13
BrainstormNew from COVID on Twitter: Michael Lin, MD PhD   (@michaelzlin): So to my extended family of 23M Taiwanese: @EricTopol's post is wrong and harmful. Taiwan is facing disaster if Omicron surges faster than vaccination.Get your family members vaccinated now, if they haven't already, especially the older [... want %more?] → https://twitter.com/michaelzlin/status/151953348592856678606:32
BrainstormNew from COVID on Twitter: Michael Lin, MD PhD   (@michaelzlin): So to my extended family of 23M Taiwanese: If you saw @EricTopol's post, it's wrong and harmful. Taiwan is facing disaster if Omicron surges faster than vaccination.Get your family members vaccinated now, if they haven't already, especially the [... want %more?] → https://twitter.com/michaelzlin/status/151953662086456115206:42
BrainstormNew from Reddit (test): CoronaVirus_2019_nCoV: Fifth Wave: Race on to study new mutations as Omicron BA.4 and BA.5 likely cause of 5,000 new SA Covid cases overnight → https://old.reddit.com/r/CoronaVirus_2019_nCoV/comments/udneg2/fifth_wave_race_on_to_study_new_mutations_as/07:11
BrainstormUpdates for Bavaria, Germany: +44066 cases, +92 deaths since 2 days ago — Baden-Wurttemberg, Germany: +33914 cases, +49 deaths since 2 days ago — Hesse, Germany: +23027 cases, +38 deaths since 2 days ago — Lombardy, Italy: +13110 cases, +26 deaths since a day ago08:03
BrainstormNew from MedicineNet: (news): Tough COVID Measures Were Tough on Mental Health → http://www.medicinenet.com/script/main/art.asp08:08
BrainstormNew from COVID on Twitter: Dr Emma Hodcroft (@firefoxx66): Despite my precarity, I'm lucky: I worked with great people in the pandemic, published, & gained a reputation through my scicomm work.But *so* much research in academia - & the pandemic!! - is done by precariously employed ppl who may not have gained as [... want %more?] → https://twitter.com/firefoxx66/status/151957253052007219209:06
BrainstormNew from COVID on Twitter: Marc Veldhoen (@Marc_Veld): If you stand up for vaccine science, we’ll stand up for you.The full strategy "how-to" guide to prepare for, defend against, and clean up after an online anti-vaxx attack.shotsheard.org → https://twitter.com/Marc_Veld/status/151957449086226432109:16
BrainstormNew from COVID on Twitter: Dr Emma Hodcroft (@firefoxx66): As many have said, this is absolutely normal in academia (sadly). However, after COVID I also think we have to consider: how will we be able to honestly advise future post-docs in a future pandemic? Let's not make it  a difficult choice to do right by the [... want %more?] → https://twitter.com/firefoxx66/status/151957674035133645309:26
BrainstormNew from COVID on Twitter: Marc Veldhoen (@Marc_Veld): Governments have a duty if care towards their citizens, to protect them against unnecessary harm such as a preventable infectious disease. news.sky.com/story/covid-19… → https://twitter.com/Marc_Veld/status/151957915596430950509:35
BrainstormNew from StatNews: How Paxlovid came to be: From the germ of an idea to a vital tool against Covid: The story of Paxlovid is a reminder that the path from a biological idea to a useable medicine depends on thousands of decisions, any of which can result in the… → https://www.statnews.com/2022/04/28/how-paxlovid-came-to-be-from-the-germ-of-an-idea-to-a-vital-tool-against-covid/10:53
BrainstormNew from StatNews: First Opinion: Opinion: Even when the pandemic fades, the depression it has wrought will linger → https://www.statnews.com/2022/04/28/pandemic-mental-health-impact-adults-depression/11:12
BrainstormNew from PubMed: Treatment of post-intensive care tracheal stenosis after previous covid-19 pneumonia: CONCLUSION: Patients after invasive mechanical ventilation for COVID-19 pneumonia are at high risk of cicatricial tracheal stenosis and require follow-up. Circular tracheal resection ensures early rehabilitation and favorable [... want %more?] → https://pubmed.ncbi.nlm.nih.gov/35477194/11:53
BrainstormUpdates for Taiwan: +11508 cases, +2 deaths since a day ago12:02
Guest42Hello everyone12:42
Guest42Some private commentators in Chinese Mainland pointed out that some states in the United States have not approved Paxlovid12:44
Guest42is it true12:44
BrainstormUpdates for Finland: +22541 cases, +301 deaths, +75703 tests since 7 days ago13:11
BrainstormNew from NPR Science: Moderna asks FDA to authorize first COVID-19 vaccine for very young children: The company says a low-dose version of its vaccine triggers an immune response in children ages 6 months to less than 6 years [... want %more?] → https://www.npr.org/sections/health-shots/2022/04/28/1095052893/moderna-asks-fda-to-authorize-first-covid-19-vaccine-for-very-young-children13:12
BrainstormNew from COVID on Twitter: Tulio de Oliveira (@Tuliodna): This once again highlights the importance of continued global genomic surveillance and variant analysis in real-time to characterize the continuing evolution ofSARS-CoV-2. There is nothing to panic, SA knows how to deal with new waves & mostly important is to [... want %more?] → https://twitter.com/Tuliodna/status/151963869705401958413:32
BrainstormNew from BMJ: Covid-19: Is the US compensation scheme for vaccine injuries fit for purpose?: We have amended this online article by Maryanne Demasi (BMJ 2022;377:o919; doi:10.1136/bmj.o919) to state that Chris Dreisbach is a board member of React 19, not its chair, and that the article was... → http://www.bmj.com/content/377/bmj.o1073.short13:41
BrainstormNew from BMJ: Mind your language to catalyse the patient revolution: Covid—wrongly—stalled the patient revolution. The voices of patients and citizens were lost amid responses to the pandemic that were too self-absorbed to consider the views of the people it affected... → http://www.bmj.com/content/377/bmj.o1071.short13:51
BrainstormNew from COVID on Twitter: Tom Wenseleers (@TWenseleers): @Tuliodna @_nickdavies @C_Althaus ...and on your earlier Omicron Nature study. nature.com/articles/s4158… Better yet: it was openly available on Github: github.com/nicholasdavies…. My please to have been of some help! → https://twitter.com/TWenseleers/status/151964681092253286414:01
undefined_bobGuest42: Paxlovid got an emergency use authorization from the FDA. Thats not a state thing. And I couldn't find informations about this. Whoever pointed that should should be able to tell you which states...14:13
BrainstormNew from COVID on Twitter: Josiah 'So Mild' Grindrod (@JT_Grindrod): Can we please point and laugh at this theory? One of the clusters of cases was in Alabama, probably one of the least locked down states, and yet somehow this is lockdown's fault. Lmaotwitter.com/andrwilliams11… → https://twitter.com/JT_Grindrod/status/151965375887085158414:31
BrainstormNew from COVID on Twitter: Gunhild Alvik Nyborg (@GANyborg): SARS-CoV-2 associated hepatitis is also seen in children"We mention another unique presentation subsequent to asymptomatic infection of SARS-CoV-2, a transient form of hepatitis designated as COVID-19 Associated Hepatitis in Children (CAH-C)."From India: [... want %more?] → https://twitter.com/GANyborg/status/151965730113684275314:41
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): The remarkable backstory of how Paxlovid was discovered and validated in record time, despite multiple obstacles, and pushed forward, ironically, by a vaccine scientiststatnews.com/2022/04/28/how… by @matthewherper @statnews → https://twitter.com/EricTopol/status/151966174326530457615:01
de-facto%title https://www.who.int/emergencies/disease-outbreak-news/item/acute-hepatitis-of-unknown-aetiology---the-united-kingdom-of-great-britain-and-northern-ireland15:10
Brainstormde-facto: From www.who.int: Acute hepatitis of unknown aetiology – the United Kingdom of Great Britain and Northern Ireland15:10
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): While Paxlovid blocks #SARSCoV2 replication and has very high clinical efficacy, there are uncommon cases of relapse. This is the first such case reportresearchsquare.com/article/rs-158… pic.twitter.com/muyURJ35RW → https://twitter.com/EricTopol/status/151966469886550835315:11
BrainstormNew from Science-Based Medicine: The search for long COVID treatments: What are current treatments for long COVID, and are they effective? The post  first appeared on Science-Based Medicine . → https://sciencebasedmedicine.org/the-search-for-long-covid-treatments/15:22
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): A 2nd booster (4th dose) halved the rate of death or  need for mechanical ventilation as compared with 3 vaccine doses (post 5 months) among hospitalized patients of advanced agemedrxiv.org/content/10.110… → https://twitter.com/EricTopol/status/151966779175798784215:32
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): When you've previously hit 1.4 million new cases in a day, 89,000 can seem low.It isn't.And that's a small fraction of the real denominator for the ongoing BA.2/BA2.12.1 wave in the US that's getting legs@OurWorldInData pic.twitter.com/SFwXcjX8Yz → https://twitter.com/EricTopol/status/151967276036817305615:52
BrainstormUpdates for Latvia: +2958 cases, +4634 tests since a day ago — United Kingdom: +1166 cases since 19 hours ago16:00
BrainstormNew from COVID on Twitter: Michael Lin, MD PhD   (@michaelzlin): Excited and honored to be part of the 2022 class of Harrington Discovery Institute Scholar-Innovators. This program will allow us to further improve our boceprevir-based SARSCOV2 protease inhibitors. We're going to need more than Paxlovid. twitter.com/UH_RE_Institut… → https://twitter.com/michaelzlin/status/151968770696756019316:43
BrainstormNew from COVID on Twitter: Gunhild Alvik Nyborg (@GANyborg): “In conjunction with recent related findings, this work presents compelling evidence of SARS-CoV-2 infection in the gastrointestinal tract and suggests a possible role for long-term infection of the gastrointestinal tract in syndromes such as “long [... want %more?] → https://twitter.com/GANyborg/status/151968872251782758616:53
BrainstormUpdates for Canada: +9205 cases, +90 deaths since 21 hours ago17:02
BrainstormNew from ClinicalTrials.gov: (news): To Assess the Safety and Tolerability of MTx-COVAB36 as a Therapeutic and Prophylactic Treatment Against COVID-19. → https://clinicaltrials.gov/ct2/show/NCT0535143717:04
BrainstormNew from LitCovid: (news): COVID-19 vaccine wastage in the midst of vaccine inequity: causes, types and practical steps. → https://www.ncbi.nlm.nih.gov/research/coronavirus/publication/3547426717:35
BrainstormNew from ClinicalTrials.gov: (news): Evaluation of the Effects of Covid 19 Infection on Bone Remodeling and Bone Fragility → https://clinicaltrials.gov/ct2/show/NCT0535229517:46
BrainstormNew from ClinicalTrials.gov: (news): Immunotherapy for Neurological Post-Acute Sequelae of SARS-CoV-2 → https://clinicaltrials.gov/ct2/show/NCT0535077417:56
BrainstormUpdates for Germany: +225 deaths since 23 hours ago17:59
BrainstormNew from ClinicalTrials.gov: (news): Phase 2b/3 Trial of NuSepin  in COVID-19 Pneumonia Patients → https://clinicaltrials.gov/ct2/show/NCT0535234718:16
BrainstormNew from WebMD: Fauci Clarifies 'Out of the Pandemic Phase' Comment as Experts Agree: After Anthony Fauci made national headlines with a proclamation that the U.S. COVID-19 pandemic is over, he walked back his comments. → https://www.webmd.com/lung/news/20220428/fauci-out-of-pandemic-phase-experts-agree18:36
BrainstormUpdates for Italy: +70034 cases, +131 deaths, +441526 tests since 22 hours ago19:02
BrainstormNew from StatNews: Listen: How cancer-killing cell therapies work, biotech’s endless downturn, & an FDA conundrum: Can rewired cells cure some patients' cancer? Do biotech stocks ever go up? And why's it taking so long to get kids vaccinated for Covid-19? All that and more on… → https://www.statnews.com/2022/04/28/podcast-cancer-cell-therapies-biotech-downturn-fda/19:35
whytekDo any of you good people know of any reearch that looked at VOCs and covid?19:40
whytekThis paper laments that there has not been research on specifically VOCs and contagion/mortality, and suggests that there should be. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7345938/19:40
whytekAlso says research shows a definate link between Particulate Matter pollution and Covid. but we knew that..19:40
whytekI didn't know: of the coronavirus deaths across 66 regions in Italy, Spain, France and Germany, 78% of them occurred in five of the most polluted regions.19:41
whytekthat's apart from the 10 mil that air pollution just killed anyways..19:42
whytekok 6 mil according to https://ourworldindata.org/air-pollution#air-pollution-is-one-of-the-world-s-leading-risk-factors-for-death19:43
whytekthat's about on a par with covid-19, right?19:44
whytekoh now it's much more.. covid's been around for more than 2 years.19:44
BrainstormNew from COVID on Twitter: Gunhild Alvik Nyborg (@GANyborg): French study on the course of post COVID symptoms over time. Among patients symptomatic 2 mo after COVID, 85% still had symptoms after 1 year. Of 53 registered symptoms,27 improved18 were stable8 increased over timeImpact on lives increased after 6 mo. [... want %more?] → https://twitter.com/GANyborg/status/151973450792189132819:55
whytekI guess maybe the blow back against associating air pollution with covid maybe prevented reasearch on VOCs?19:55
BrainstormNew from COVID on Twitter: Tom Wenseleers (@TWenseleers): Updated estimate of the Omicron BA.4 & BA.5 growth advantage in South Africa in nice new study of @houzhou & @Tuliodna and colleagues, ceri.org.za/publication/?t…. twitter.com/Tuliodna/statu… → https://twitter.com/TWenseleers/status/151973641371304755220:05
BrainstormUpdates for Japan: +38132 cases, +39 deaths since 13 hours ago — United Kingdom: +14681 cases, +248 deaths since 22 hours ago — Canada: +12850 cases, +124 deaths since 23 hours ago20:10
BrainstormNew from COVID on Twitter: Ridhwaan Suliman (@rid1tweets): A useful measure to quantify the increase, or decline, in new #COVID19 infections is to look at the week-on-week % change or doubling time  Over the past week, cases in South Africa   have increased by 120% or doubled in 6 days, but a slight decline in [... want %more?] → https://twitter.com/rid1tweets/status/151974144904201830420:25
BrainstormNew from WebMD: Moderna Seeks OK for Young Kids' COVID Vaccine as Parents Wait: Pfizer's request for the youngest kids is expected next. But there are a lot of moving parts, and families and doctors alike are concerned the FDA will not act quickly enough. → https://www.webmd.com/vaccines/covid-19-vaccine/news/20220428/moderna-seeks-ok-for-young-kids-covid-vaccine21:05
BrainstormUpdates for France: +16 cases since 23 hours ago21:07
Arsaneritnot many21:30
BrainstormNew from Pfizer: Pfizer Announces 2022 Shareholder Meeting Preliminary Results:  kimkevin Thu, 04/28/2022 - 15:26 Thursday, April 28, 2022 - 03:30pm NEW YORK, April 28, 2022 – Pfizer Inc. (NYSE: PFE) today held its Annual Meeting of Shareholders in a [... want %more?] → https://www.pfizer.com/news/press-release/press-release-detail/pfizer-announces-2022-shareholder-meeting-preliminary21:45
BrainstormUpdates for Guatemala: +930 cases, +7 deaths since a day ago22:03
BrainstormNew from COVID on Twitter: Marc Veldhoen (@Marc_Veld): our data emphasize the relevance of vaccine-induced spike-specific CD8+ T-cell responses in combating VOCs including Omicron/B.1.1.529 and support the benefit of boosting convalescent individuals with mRNA vaccines. pic.twitter.com/BcEJaMphCp → https://twitter.com/Marc_Veld/status/151977382044127232322:24
BrainstormNew from CIDRAP: Initial vital signs, labs better predict COVID severity than chronic conditions: Mary Van Beusekom | News Writer | CIDRAP News Apr 28, 2022 Risk factors for severe COVID varied by age, with BMI and underlying conditions more notable [... want %more?] → https://www.cidrap.umn.edu/news-perspective/2022/04/initial-vital-signs-labs-better-predict-covid-severity-chronic-conditions22:43
BrainstormNew from CIDRAP: COVID rises in Africa and the Americas, Moderna submits EUA for use in young kids: Lisa Schnirring | News Editor | CIDRAP News Apr 28, 2022 Cases are rising in South Africa, where researchers are closely tracking two new Omicron [... want %more?] → https://www.cidrap.umn.edu/news-perspective/2022/04/covid-rises-africa-and-americas-moderna-submits-eua-use-young-kids22:53
BrainstormUpdates for Canada: +12442 cases since 23 hours ago23:00
BrainstormNew from ProPublica: Louisiana Lawmakers Could Limit Solitary Confinement for Teens Following Alarming Revelations: by Annie Waldman , ProPublica, Beth Schwartzapfel , The Marshall Project , and Erin Einhorn , NBC News ProPublica is a [... want %more?] → https://www.propublica.org/article/louisiana-lawmakers-could-limit-solitary-confinement-for-teens-following-alarming-revelations#132230723:03

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