libera/##covid-19/ Tuesday, 2022-05-03

BrainstormNew from WebMD: NYC Raises COVID Alert Level to Medium: New York City on Monday raised its COVID alert level from low to medium as  the Omicron subvariant pushs up COVID-19 case numbers. → https://www.webmd.com/vaccines/covid-19-vaccine/news/20220502/nyc-raises-covid-alert-level-to-medium00:11
BrainstormNew from Ars Technica: Science: Omicron subvariants BA.4, BA.5 evade protection from earlier omicron infection → https://arstechnica.com/?p=185174900:58
Trippy72894what's the story now with variants and this all getting terrible again? are we out of the woods yet? will we be?01:25
BrainstormNew from r/COVID19: COVID19: Remdesivir and three other drugs for hospitalised patients with COVID-19: final results of the WHO Solidarity randomised trial and updated meta-analyses → https://old.reddit.com/r/COVID19/comments/uh1xgw/remdesivir_and_three_other_drugs_for_hospitalised/01:27
BrainstormNew from COVID on Twitter: Paul K VAxxed (@paulkva): @ASlavitt “…we need to update the vaccines.”Makes sense. So what is already being done about that? I’ve heard very little about Omicron-specific and other trials, which leads me to think broad availability would still be months away. Is that accurate? → https://twitter.com/paulkva/status/152126957360920985901:56
BrainstormUpdates for Canada: +2417 cases since 9 hours ago02:00
LjL<CarlSagan> [Ars Technica - Science] Omicron subvariants BA.4, BA.5 evade protection from earlier omicron infection https://arstechnica.com/?p=1851749 2022-05-02T22:44:3602:55
BrainstormUpdates for Micronesia: +2 cases since 5 days ago03:03
BrainstormUpdates for Australia: +35295 cases, +55 deaths since 23 hours ago — Jamaica: +321 cases, +5 deaths, +7973 tests since 3 days ago04:06
BrainstormNew from COVID on Twitter: Michael Lin, MD PhD   (@michaelzlin): It's BARDA that's tasked with giving early funding to vaccines but a citizen making a valid suggestion shouldn't be required to identify the right federal agency in order to get a valid response by the former COVID "czar." Seems who-me-ism is a side [... want %more?] → https://twitter.com/michaelzlin/status/152133345421384089805:48
BrainstormUpdates for Germany: +113522 cases since 23 hours ago06:05
BrainstormNew from Reddit (test): Covid2019: Symptom data help predict COVID-19 admissions - Uppsala University, Sweden → https://old.reddit.com/r/Covid2019/comments/uh9dal/symptom_data_help_predict_covid19_admissions/07:52
BrainstormNew from Reddit (test): Covid2019: UZH - Long-Covid-BetroffeneTackling the Consequences of Long Covid A research team at the University of Zurich has helped people affected by Long Covid identify the problems they most urgently want scientists to tackle, through a [... want %more?] → https://old.reddit.com/r/Covid2019/comments/uh9f8o/uzh_longcovidbetroffenetackling_the_consequences/08:02
BrainstormUpdates for New York, United States: +8136 cases, +17 deaths since a day ago — Western Australia, Australia: +7578 cases since a day ago — New Jersey, United States: +3015 cases, +14 deaths since a day ago — Delaware, United States: +703 cases, +12 deaths since 3 days ago08:11
BrainstormNew from MedicineNet: (news): Therapies That Can Help Ease Long COVID Breathlessness, Fatigue → http://www.medicinenet.com/script/main/art.asp09:00
BrainstormNew from r/Coronavirus: Daily Discussion Thread | May 03, 2022: Please refer to our Wiki for more information on COVID-19 and our sub. You can find answers to frequently asked questions in our FAQ , where there is valuable information such as our: → https://old.reddit.com/r/Coronavirus/comments/uhabh2/daily_discussion_thread_may_03_2022/09:09
SmilesMy colleague has made the claim that the more transmissive viruses are generally less dangerous. How can I best challenge this claim?10:03
SmilesI see there is https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7095397/10:03
BrainstormUpdates for Taiwan: +23134 cases, +5 deaths, +64208 tests since a day ago10:10
BrainstormNew from COVID on Twitter: (translated) Marc Veldhoen (@Marc_Veld): With recent data from lareb, with 373 heart infections, is that a lot? Is there a direct link with vaccines?Here's a breakdown of the actual data: twitter.com/PostvanFenna/s… → https://twitter.com/Marc_Veld/status/152140650653678387410:36
BrainstormNew from StatNews: Health: More uniformly infectious, more treatable, more genetically predictable: How coronavirus is getting closer to flu → https://www.statnews.com/2022/05/03/more-uniformly-infectious-more-treatable-more-genetically-predictable-how-coronavirus-is-getting-closer-to-flu/10:46
BrainstormNew from BMJ: Can the world become a place where the planet and all people flourish after the pandemic?: In 2015, the world adopted 17 sustainable development goals (SDGs) with 169 targets to be achieved by 2030. These goals aimed to create a world in which people and the planet flourish. They were more... → http://www.bmj.com/content/377/bmj-2021-067872.short11:34
BrainstormNew from COVID on Twitter: Tom Wenseleers (@TWenseleers): New study confirms that Omicron BA.4&5 gets its selective benefit from immune escape, but that it also has lower ACE2 binding affinity. Hopefully means that immune escape is traded off against contagiousness and that this could cause evolution towards lower [... want %more?] → https://twitter.com/TWenseleers/status/152142271742103142411:44
BrainstormNew from PubMed: Expression of prostate-specific membrane antigen in the neovasculature of primary tumors and lymph node metastasis of laryngeal squamous cell carcinomas: CONCLUSION: Our study suggests that higher PSMA expression is associated with cartilage invasion, local invasion, and advanced-stage of disease. PSMA expression [... want %more?] → https://pubmed.ncbi.nlm.nih.gov/35501674/11:54
BrainstormNew from Pfizer: Pfizer Reports First-Quarter 2022 Results:  Anonymous (not verified) Tue, 05/03/2022 - 06:45 Tuesday, May 03, 2022 - 06:45am First-Quarter 2022 Revenues of $25.7 Billion, Reflecting 82% Operational Growth; Excluding Contributions from Comirnaty (1) and [... want %more?] → https://www.pfizer.com/news/press-release/press-release-detail/pfizer-reports-first-quarter-2022-results12:53
BrainstormNew from Politico: WHO: Obesity in Europe at ‘epidemic proportions’: Report flags meal delivery apps as possibly contributing to the obesity problem. → https://www.politico.eu/article/who-obesity-in-europe-at-epidemic-proportions/13:51
BrainstormNew from Reddit (test): nCoV: Global COVID Cases For 03MAY22 → https://old.reddit.com/r/nCoV/comments/uhej6t/global_covid_cases_for_03may22/14:11
BrainstormNew from Contagion Live: COVID-19 Pandemic Disrupted Dengue Transmission: Historically low incidence of dengue in southeast Asia and Latin America linked to COVID-19 restrictions suggests potential future interventions. → https://www.contagionlive.com/view/covid-19-pandemic-disrupted-dengue-transmission15:09
BrainstormNew from COVID on Twitter: Bloom Lab (@jbloom_lab): @TWenseleers @SCOTTeHENSLEY ... so there are lots of "decoy" molecules w sialic acid (eg mucins) & sialic acid on producing cells that can bind up virions. But ACE2 much less abundant & probably not on decoys much, so unclear if factors that make too much affinity [... want %more?] → https://twitter.com/jbloom_lab/status/152147755379755827515:19
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): First assessment of the immune escape of BA.2.12.1 (headed toward US dominance), which is substantial, more than BA.2, with little cross-immunity with BA.1, similar to BA.4 and BA.5, and questioning the value of Omicron BA.1 booster vaccinesbiorxiv.org/content/10.110… → https://twitter.com/EricTopol/status/152147936510354637415:29
BrainstormNew from r/COVID19: COVID19: Multivariate profile and acute-phase correlates of cognitive deficits in a COVID-19 hospitalised cohort → https://old.reddit.com/r/COVID19/comments/uhg8sd/multivariate_profile_and_acutephase_correlates_of/15:39
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): We'll get a CDC update later today but likely BA.2.12.1 is >40% by now covid.cdc.gov/covid-data-tra… pic.twitter.com/VrJHSxSDP1 → https://twitter.com/EricTopol/status/152148444011082956815:49
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): Just updated now, 38.5% nationally as of April 30Only region 2 (includes New York) is BA.2.12.1 dominant (at 62%) pic.twitter.com/654v8nfzP3 → https://twitter.com/EricTopol/status/152148836226317517215:58
BrainstormNew from Reddit (test): nCoV: COVID fifth wave 'like no other experienced in SA' - should we be worried? | 03MAY22 → https://old.reddit.com/r/nCoV/comments/uhgqp4/covid_fifth_wave_like_no_other_experienced_in_sa/16:09
BrainstormNew from Reddit (test): nCoV: South Africa's latest surge a preview of Covid-19's next chapter? | 02MAY22 → https://old.reddit.com/r/nCoV/comments/uhgxzx/south_africas_latest_surge_a_preview_of_covid19s/16:19
BrainstormNew from Reddit (test): nCoV: New study proves correct dosage for ultraviolet disinfection against COVID | 02MAY22 → https://old.reddit.com/r/nCoV/comments/uhh8hv/new_study_proves_correct_dosage_for_ultraviolet/16:29
BrainstormNew from COVID on Twitter: Tulio de Oliveira (@Tuliodna): Omicron replaced Delta in the U.K. by end 2021! Why do the authors failed to discuss their country's unethical travel ban to southern Africa??? U.K. Great science & Hypocrisy that damaged our economy, increased discrimination & had no effect on [... want %more?] → https://twitter.com/Tuliodna/status/152150078759936414816:49
BrainstormUpdates for Canada: +1829 cases, +3 deaths since 21 hours ago17:03
BrainstormNew from ClinicalTrials.gov: (news): The Effects of Long-Term Mask Use in the Pandemic Period → https://clinicaltrials.gov/ct2/show/NCT0535866517:09
ublx%title https://twitter.net/MoriartyLab/status/152056466621646848018:02
* ublx pokes Brainstorm18:03
* Brainstorm starts to reek ublx with some gloomy worriment 18:03
LjL%title https://twitter.net/MoriartyLab/status/152056466621646848018:03
ublxwell: "38% of all of Canada's reported COVID hospitalizations to date have been in the last 4 months"18:04
ublxstriking framing18:04
LjL%title test18:04
BrainstormLjL, the command line provided is invalid18:04
LjL%title https://twitter.net/MoriartyLab/status/152056466621646848018:05
LjLprobably something (not) timing out...18:05
LjL%title https://google.com18:05
BrainstormLjL: From google.com: Google18:05
ublxoh lol18:05
ublxtwitter.NET18:05
ublx%title https://twitter.com/MoriartyLab/status/152056466621646848018:06
Brainstormublx: From twitter.com: Tara Moriarty (@MoriartyLab): "38% of all of Canada's reported COVID hospitalizations to date have been in the last 4 months 28% of reported ICU admissions of the entire epidemic in the last 4 months [...]18:06
BrainstormUpdates for Germany: +188 deaths since 12 hours ago — France: +122 cases since 20 hours ago18:06
LjLoh18:06
Brainstormublx, the URL could not be loaded18:07
BrainstormNew from ClinicalTrials.gov: (news): Musculoskeletal Pain in Long COVID → https://clinicaltrials.gov/ct2/show/NCT0535811918:07
BrainstormLjL, the URL could not be loaded18:08
BrainstormKeyError: '/home/brainstorm/brainstorm/bot/modules/utils.py' (file "/home/brainstorm/.cache/pypoetry/virtualenvs/brainstorm-vhxt35-a-py2.7/lib/python2.7/linecache.py", line 69, in checkcache)18:09
LjL%title https://twitter.net/MoriartyLab/status/152056466621646848018:13
BrainstormLjL, the URL could not be loaded18:13
BrainstormNew from ClinicalTrials.gov: (news): Efficacy and Safety of Nasal Spray Solution Containing Human IgG1 Anti-SARS-CoV-2 Antibody Cocktail → https://clinicaltrials.gov/ct2/show/NCT0535887318:17
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): Canada's BA.2 wave is on the descent, but for the first time in the pandemic it had higher hospitalizations and deaths than the US@OurWorldInData pic.twitter.com/E3YiqrKqGL → https://twitter.com/EricTopol/status/152152427640635392118:27
BrainstormUpdates for Italy: +62409 cases, +153 deaths, +411047 tests since 23 hours ago19:08
BrainstormNew from WebMD: FDA Warns of Counterfeit Home COVID Test Kits: The FDA warns Americans to watch out for phony at-home, over-the-counter COVID tests that look a lot like the real things. → https://www.webmd.com/lung/news/20220503/fda-warns-of-counterfeit-home-covid-19-test-kits19:15
BrainstormUpdates for Canada: +2965 cases, +42 deaths since 23 hours ago20:10
BrainstormNew from BMJ: No minister, a “protective ring” was not thrown around care homes: Margaret Thatcher famously said “Advisers advise, ministers decide.”1 Yet, throughout the covid-19 pandemic this distinction has often seemed blurred. Ministers justified decisions by claiming they... → http://www.bmj.com/content/377/bmj.o1116.short20:44
BrainstormNew from r/COVID19: COVID19: CDC restates recommendation for masks on planes, trains → https://old.reddit.com/r/COVID19/comments/uhmvhz/cdc_restates_recommendation_for_masks_on_planes/20:54
BrainstormNew from CIDRAP: News Scan for May 03, 2022: Severe COVID and cognitive deficits Hard-to-read COVID vaccine info Hospital antimicrobial stewardship → https://www.cidrap.umn.edu/news-perspective/2022/05/news-scan-may-03-202221:43
BrainstormUpdates for France: +67113 cases, +120 deaths since 22 hours ago — United Kingdom: +35518 cases, +407 deaths since 22 hours ago — Spain: +57329 cases, +206 deaths since a day ago — Germany: +21902 cases, +234 deaths since 15 hours ago22:03
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): High-quality masks (N95, KN95) are important to reduce the the risk of infection and transmission by the Omicron family variants. But so is the fit. aip.scitation.org/doi/10.1063/5.… → https://twitter.com/EricTopol/status/152158229480007680022:11
BrainstormNew from CIDRAP: COVID-19 tied to adverse maternal outcomes, preterm birth: Mary Van Beusekom | News Writer | CIDRAP News May 03, 2022 Pregnant women with COVID-19 had more than twice the risk of hospitalization and ICU stay. → https://www.cidrap.umn.edu/news-perspective/2022/05/covid-19-tied-adverse-maternal-outcomes-preterm-birth22:21
BrainstormNew from COVID on Twitter: Scott Gottlieb, MD (@ScottGottliebMD): FDA writing in @NEJM on the use of Real World Evidence in drug development and post market Pharmacovigilance“In general, the pandemic has accelerated awareness and adoption of RWD and RWE, but their use was already increasing before the [... want %more?] → https://twitter.com/ScottGottliebMD/status/152159140753801625622:50
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): Summary table of features of the key Omicron lineagesReferences:Cao et al biorxiv.org/content/10.110…Tegally et almedrxiv.org/content/10.110…Yamasoba et al cell.com/cell/fulltext/… pic.twitter.com/Ro4N0JQOUT → https://twitter.com/EricTopol/status/152159607622181273623:10
BrainstormNew from COVID on Twitter: Scott Gottlieb, MD (@ScottGottliebMD): More evidence BA.4 and BA.5 and now BA.2.12.1, (which is highly prevalent in NY) escape antibodies generated by infection with BA.1, increasing likelihood of reinfection, and may also have more immune evasion to current vaccines than BA.2 [... want %more?] → https://twitter.com/ScottGottliebMD/status/152160005275768013123:29
BrainstormNew from COVID on Twitter: Marc Veldhoen (@Marc_Veld): Omicron can evolve mutations to specifically evade humoral immunity elicited by BA.1 infection. The continuous evolution of Omicron poses great challenges to SARS-CoV-2 infection. But disease should be limited! And immunity will build to force viral evolution. → https://twitter.com/Marc_Veld/status/152160239727715123223:39

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