libera/##covid-19/ Wednesday, 2022-06-08

BrainstormUpdates for Kenya: +163 cases since a day ago — Malawi: +14 cases, +413 tests since a day ago00:07
BrainstormNew from COVID on Twitter: Scott Gottlieb, MD (@ScottGottliebMD): CDC says BA.4, BA.5 represent high percentage of cases in region that includes Texas, New Mexico, Oklahoma, Arkansas, Louisiana; but much lower in northeast which had big BA.2 wave. Question now: Can BA.4, BA.5 become dominant in places with big [... want %more?] → https://twitter.com/ScottGottliebMD/status/153429543983459123500:09
BrainstormNew from COVID on Twitter: Michael Lin, MD PhD   (@michaelzlin): Hmm, Novavax believes features of its vaccine engender broad cross-protection. I wonder what they are referring to.Might be something else, or might be the S1-S2 balance I hypothesized below.twitter.com/michaelzlin/st… pic.twitter.com/5CkEFpHFTw → https://twitter.com/michaelzlin/status/153429969588280934500:29
BrainstormNew from COVID on Twitter: Michael Lin, MD PhD   (@michaelzlin): The one abstention by Bruce Gellin was due to his dissatisfaction on lack of data on Omicron VE, so that immunogenicity data would have been relevant. In any case the links to the briefing docs are here if you want to look through them. fda.gov/advisory-commi… → https://twitter.com/michaelzlin/status/153430219359916441600:38
BrainstormNew from COVID on Twitter: Michael Lin, MD PhD   (@michaelzlin): Neither FDA nor Novavax's briefing docs mentioned the nAb results against Omicron, published in the link below. Maybe Novavax thought they'd raise more Qs to include in the doc, but Dubovsky must have meant those when he said immunogenicity data look [... want %more?] → https://twitter.com/michaelzlin/status/153430640091409203300:57
BrainstormUpdates for Brazil: +71045 cases, +242 deaths since 22 hours ago — Bahrain: +997 cases, +5679 tests since a day ago — Germany: +16601 cases, +24 deaths since 6 hours ago — Montenegro: +71 cases, +744 tests since a day ago01:03
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): Reduction of severe Covid increased when Evusheld given early, and present/similar magnitude across nearly all subgroups pic.twitter.com/MbtUtdXhTq → https://twitter.com/EricTopol/status/153431002793847193901:07
BrainstormNew from COVID on Twitter: Michael Lin, MD PhD   (@michaelzlin): Ultimately in the FDA system the sponsor is responsible for making the strongest possible case for approval. The advisors are there to say no. And Novavax doesn't seem to have the same hard-hitting tactics as other companies. → https://twitter.com/michaelzlin/status/153431226252943360001:17
BrainstormNew from COVID on Twitter: Michael Lin, MD PhD   (@michaelzlin): Or there was J&J which wrote in their VRBPAC document their shot 1 gave "strong" "long-lasting" protection and shot 2 "substantially increases" antibodies, when both pre-boost and post-boost levels were far below other vax. fda.gov/media/152954/d… → https://twitter.com/michaelzlin/status/153431226561632665601:26
BrainstormNew from Reddit (test): CoronaVirus_2019_nCoV: First Description of Serological Evidence for SARS-CoV-2 in Lactating Cows → https://old.reddit.com/r/CoronaVirus_2019_nCoV/comments/v7b3ui/first_description_of_serological_evidence_for/01:36
BrainstormNew from COVID on Twitter: Theo Sanderson (@theosanderson): (SARS-CoV-2 sized genomes) → https://twitter.com/theosanderson/status/153432691665581260902:14
BrainstormNew from r/COVID19: COVID19: The effect of strict lockdown on Omicron SARS-CoV-2 variant transmission in Shanghai → https://old.reddit.com/r/COVID19/comments/v7cb54/the_effect_of_strict_lockdown_on_omicron_sarscov2/02:42
BrainstormUpdates for Dominican Rep.: +1482 cases, +2 deaths, +9576 tests since 2 days ago — Guatemala: +1132 cases, +10 deaths, +9422 tests since 22 hours ago — Indonesia: +518 cases, +2 deaths, +79279 tests since a day ago — Norway: +389 cases since a day ago03:03
BrainstormNew from ##covid-19 Zotero group: The effect of strict lockdown on Omicron SARS-CoV-2 variant transmission in Shanghai: Type Report Author Haibo Yang Author Hao Nie Author Dewei Zhou Author Yujia Wang Author Wei Zuo URL https://www.medrxiv.org/content/10.1101/2022.05.22.22275423v1 Rights   2022, Posted by Cold Spring [... want %more?] → https://www.zotero.org/groups/covid_links/items/ZPTIT8C203:11
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): more Covid in Florida pic.twitter.com/1rYT5tf2XW → https://twitter.com/EricTopol/status/153434320406942924803:20
BrainstormNew from Retraction Watch: A paper claimed to describe ‘the first potent and specific anti-COVID-19 drug.’ Now it’s retracted.: A paper about the discovery of “the first potent and specific anti-COVID-19 drug” has been retracted [... want %more?] → https://retractionwatch.com/2022/06/07/a-paper-claimed-to-describe-the-first-potent-and-specific-anti-covid-19-drug-now-its-retracted/03:30
BrainstormUpdates for Australia: +32964 cases, +46 deaths since 23 hours ago03:59
LjLsurely Paxlovid is the first potent and specific drug released04:16
BrainstormUpdates for South Korea: +13320 cases, +6 deaths since a day ago — Panama: +3523 cases, +3 deaths, +16091 tests since a day ago — Bolivia: +316 cases since 23 hours ago05:08
BrainstormNew from COVID on Twitter: Josiah Grindrod is usually self limiting (@JT_Grindrod): Has anyone ever seen anyone panicking over virus news since the TP panic over two years ago?No one gives a shit. You could say it's airborne rabies and most people would shrug and go on about their day. → https://twitter.com/JT_Grindrod/status/153438431710280499306:04
BrainstormNew from r/COVID19: COVID19: A More Accurate Measurement of COVID-19 Hospitalizations → https://old.reddit.com/r/COVID19/comments/v7gyei/a_more_accurate_measurement_of_covid19/06:51
BrainstormUpdates for Japan: +12477 cases, +88130 tests since 10 hours ago — Switzerland: +10295 cases since 13 hours ago07:01
BrainstormNew from r/Science: science: A novel vaccine showed high efficacy in the treatment of solid tumors, achieving complete clearance of these tumors and inducing long-lasting immune memory, preventing relapse of tumor growth and conferring protection against similar tumors. → https://old.reddit.com/r/science/comments/v7h8o6/a_novel_vaccine_showed_high_efficacy_in_the/07:20
BrainstormNew from COVID on Twitter: Bloom Lab (@jbloom_lab): Finally, I regret the #SARSCoV2 origins topic has become filled with invective & mean-spirited attacks. I see many people with diverse views being targeted with personal attacks. I know you have been the target of such attacks yourself, which is wrong. → https://twitter.com/jbloom_lab/status/153440768627151667407:39
BrainstormUpdates for California, United States: +54396 cases, +60 deaths since a day ago — Sao Paulo, Brazil: +29856 cases, +168 deaths since 5 days ago — North Rhine-Westphalia, Germany: +18607 cases, +14 deaths since a day ago — Bavaria, Germany: +14243 cases, +21 deaths since 4 days ago08:10
BrainstormNew from MedicineNet: (news): Technology Helped Kids With Type 1 Diabetes During Pandemic → http://www.medicinenet.com/script/main/art.asp08:36
BrainstormNew from r/Coronavirus: Daily Discussion Thread | June 08, 2022: Please refer to our Wiki for more information on COVID-19 and our sub. You can find answers to frequently asked questions in our FAQ , where there is valuable information such as our: → https://old.reddit.com/r/Coronavirus/comments/v7j9sr/daily_discussion_thread_june_08_2022/09:05
BrainstormUpdates for Taiwan: +80070 cases, +159 deaths, +124324 tests since a day ago10:09
BrainstormNew from EMA: Human medicine assessment reports: (news): Human medicines European public assessment report (EPAR): Adjupanrix (previously Pandemic influenza vaccine (H5N1) (split virion, inactivated, adjuvanted) GlaxoSmithKline [... want %more?] → https://www.ema.europa.eu/en/medicines/human/EPAR/adjupanrix-previously-pandemic-influenza-vaccine-h5n1-split-virion-inactivated-adjuvanted10:52
BrainstormNew from ProPublica: New York Let Residences for Kids With Serious Mental Health Problems Vanish. Desperate Families Call the Cops Instead.: by Abigail Kramer ,  THE CITY This article was produced for ProPublica’s Local Reporting Network in partnership with THE CITY . Sign up for [... want %more?] → https://www.propublica.org/article/mental-health-beds-new-york-children-disappearing#134601711:21
BrainstormNew from Virological.org: Latest topics: UPDATE: Two draft genomes from Madrid, Spain, of the Monkeypox virus 2022 outbreak: Two draft genomes from Madrid, Spain, of the Monkeypox virus 2022 outbreak Sergio Buenestado-Serrano1, Rosalía Palomino-Cabrera1, Daniel [... want %more?] → https://virological.org/t/update-two-draft-genomes-from-madrid-spain-of-the-monkeypox-virus-2022-outbreak/84812:00
BrainstormUpdates for Russia: +3646 cases, +79 deaths since a day ago12:02
BrainstormNew from Reddit (test): CoronaVirus_2019_nCoV: Covid-19 roundup: Merck, Ridgeback drop new analyses for molnupiravir; Veru submits EUA for antiviral treatment → https://old.reddit.com/r/CoronaVirus_2019_nCoV/comments/v7lwa4/covid19_roundup_merck_ridgeback_drop_new_analyses/12:09
BrainstormNew from EMA: News and press releases: EMA adopts first list of critical medicines for COVID-19  , , 08/06/2022: On 7 June 2022, EMA’s Medicines Shortages Steering Group (MSSG) adopted the list of     critical medicines for the COVID-19 public health emergency... → https://www.ema.europa.eu/en/news/ema-adopts-first-list-critical-medicines-covid-1912:58
BrainstormUpdates for Brunei: +399 cases, +1 deaths since 23 hours ago13:04
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): An Omicron (BA.1) specific booster hits immunologic and safety endpoints in a Phase 2/3 trial compared with ancestral strain booster, expected to be available in late summer/fall; @moderna_tx release, attached pic.twitter.com/84B0sJ7Eni → https://twitter.com/EricTopol/status/153449067274439475213:08
BrainstormNew from COVID on Twitter: Scott Gottlieb, MD (@ScottGottliebMD): While #CDC has test specifically for monkeypox, any one of 60+ state labs in CDC’s “Laboratory Response Network” can test for orthopoxvirusSince monkeypox is only circulating orthopoxvirus, any positive is presumed monkeypox. It equates [... want %more?] → https://twitter.com/ScottGottliebMD/status/153449896561750835313:37
BrainstormNew from COVID on Twitter: Gunhild Alvik Nyborg (@GANyborg): “Our autopsy results reveal a 16% higher SARS-CoV-2 infection rate and an 8% higher SARS-CoV-2 related mortality rate than reported by clinicians before death.” → https://twitter.com/GANyborg/status/153449938220838912213:46
BrainstormUpdates for Saudi Arabia: +1029 cases, +3 deaths since a day ago — UAE: +867 cases, +279163 tests since a day ago — Malta: +102 cases, +1029 tests since a day ago14:01
BrainstormNew from Reddit (test): nCoV: Global COVID Cases For 08JUN22 → https://old.reddit.com/r/nCoV/comments/v7nv7y/global_covid_cases_for_08jun22/14:06
BrainstormNew from r/COVID19: COVID19: Moderna Announces Omicron-Containing Bivalent Booster Candidate MRNA-1273.214 Demonstrates Superior Antibody Response Against Omicron → https://old.reddit.com/r/COVID19/comments/v7ocva/moderna_announces_omicroncontaining_bivalent/14:25
BrainstormNew from COVID on Twitter: Scott Gottlieb, MD (@ScottGottliebMD): CDC facilitating laboratory developed tests and diagnostic kits are being developed for commercial labs. CDC put primer sequences on web and is making positive controls available. But biggest bottleneck is lack of sampling. For vesicular rashes [... want %more?] → https://twitter.com/ScottGottliebMD/status/153451371321819136114:35
BrainstormNew from Reddit (test): nCoV: U.S. has wasted more than 82 million COVID vaccine doses | 06JUN22 → https://old.reddit.com/r/nCoV/comments/v7p0ye/us_has_wasted_more_than_82_million_covid_vaccine/15:05
BrainstormUpdates for Georgia: +2508 cases since a month ago — Indonesia: +520 cases, +4 deaths since 12 hours ago — Croatia: +424 cases, +3 deaths since a day ago — Qatar: +373 cases since a day ago15:10
BrainstormNew from Reddit (test): CoronaVirus_2019_nCoV: BA.5 Omicron Is Winning The Covid Variant Battle In The U.S., Especially In The Southwest: specifically in Texas and New Mexico, where together the already account for close of one-quarter of all new cases, at 22.2%. → https://old.reddit.com/r/CoronaVirus_2019_nCoV/comments/v7patx/ba5_omicron_is_winning_the_covid_variant_battle/15:15
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): More neutralizing antibodies vs Omicron with 2-fer spike mRNA (ancestral plus BA.1) than ancestral. We won't know about clinical outcomes until later this yearft.com/content/ce0597… @JamieSmythF @hannahkuchler pic.twitter.com/FbieEU47FV → https://twitter.com/EricTopol/status/153453091059853312115:44
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): At the least, the rise of BA.4/BA.5 will prolong the current US Omicron subvariant wavewsj.com/articles/ba-4-… by @jon_kamp pic.twitter.com/vGxZh23Ej0 → https://twitter.com/EricTopol/status/153453213727311052815:54
BrainstormUpdates for Canada: +3166 cases, +17 deaths since 20 hours ago16:00
BrainstormNew from Pfizer: Pfizer Invites Public to View and Listen to Webcast of Pfizer Discussion at Healthcare Conference:  Anonymous (not verified) Wed, 06/08/2022 - 10:00 Wednesday, June 08, 2022 - 10:00am NEW YORK--(BUSINESS WIRE)--Pfizer Inc. (NYSE: PFE) [... want %more?] → https://www.pfizer.com/news/press-release/press-release-detail/pfizer-invites-public-view-and-listen-webcast-pfizer-716:13
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): Encouraging new experimental results (and thread) from @PeacockFlu and colleagues to suggest an immune response to BA.1 will cross-react with BA.4/5twitter.com/PeacockFlu/sta… → https://twitter.com/EricTopol/status/153453930345117286416:23
BrainstormUpdates for Kenya: +218 cases, +5787 tests since 16 hours ago17:03
BrainstormNew from ClinicalTrials.gov: (news): Evaluation of the Immunogenicity and Safety of COVID-19 Vaccines (Ad26.COV2.S and NVX-CoV2373) → https://clinicaltrials.gov/ct2/show/NCT0540926117:12
BrainstormNew from ClinicalTrials.gov: (news): Anxiety, Depression, and Quality of Life in Patients With Fibromyalgia During the Coronavirus Disease 2019 Pandemic → https://clinicaltrials.gov/ct2/show/NCT0541080817:22
BrainstormNew from ClinicalTrials.gov: (news): Evaluation of the Immunogenicity and Safety of Sputnik V and BBIBP-CorV Vaccines for COVID-19 in Adult in Guinea → https://clinicaltrials.gov/ct2/show/NCT0540930017:32
ublxinteresting if true: https://twitter.com/Antonio_Caramia/status/153352743277448806517:33
xx%title https://twitter.com/Antonio_Caramia/status/153352743277448806517:36
Brainstormxx: From twitter.com: Antonio Caramia su Twitter: " For 9 days in a row, China   has had 0⃣ ZERO #COVID19 deaths 0⃣ ZERO #COVID19 deaths 0⃣ ZERO #COVID19 deaths The worst day was 30 April, when 8⃣5⃣ (eighty-five) deaths [...]17:36
BrainstormNew from ClinicalTrials.gov: (news): The Change of Clinical Features and Surgical Outcomes in Patients With Pressure Injury During the COVID-19 Pandemic: A Retrospective Study → https://clinicaltrials.gov/ct2/show/NCT0540917017:41
pwr22So China has beaten the Omicron?17:43
pwr22Impressive17:43
pwr22They play this game on "hard" mode, UK plays on "easy"17:43
xxwell it's easy to do when you can force the population to do whatever you want17:43
pwr22😉17:44
BrainstormUpdates for Germany: +82687 cases, +156 deaths since 23 hours ago17:59
BrainstormNew from COVID19 Vaccine Tracker: valerie: AIM Vaccine: LVRNA009 → https://covid19.trackvaccines.org/vaccines/189/18:11
BrainstormNew from COVID on Twitter: Marc Veldhoen (@Marc_Veld): twitter.com/moderna_tx/sta… → https://twitter.com/Marc_Veld/status/153457758990540800018:51
BrainstormUpdates for Italy: +22925 cases, +80 deaths, +188024 tests since a day ago19:08
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): An exceptional #LongCovid thread by @trishgreenhalgh twitter.com/trishgreenhalg… → https://twitter.com/EricTopol/status/153458832555772723219:40
BrainstormNew from r/COVID19: COVID19: Persistence of residual SARS-CoV-2 viral antigen and RNA in tissues of patients with long COVID-19 → https://old.reddit.com/r/COVID19/comments/v7vkgm/persistence_of_residual_sarscov2_viral_antigen/19:59
BrainstormUpdates for Chile: +10618 cases, +8 deaths since 23 hours ago — Malaysia: +1518 cases, +6 deaths since 23 hours ago — Canada: +3793 cases, +16 deaths since 23 hours ago20:04
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): They're still increasing during the current US Omicron subvariant wave, but at least the rate of rise is slowing@OurWorldInData pic.twitter.com/HrYFvqV25B → https://twitter.com/EricTopol/status/153459864715685888220:19
BrainstormNew from CIDRAP: COVID-19 Scan for Jun 08, 2022: Pregnancy and severe COVID in Africa COVID-19 vaccination in homeless, jails → https://www.cidrap.umn.edu/news-perspective/2022/06/covid-19-scan-jun-08-202220:39
BrainstormNew from WebMD: (news): COVID Breakthrough Infections More Likely in People Living With HIV → https://www.webmd.com/hiv-aids/news/20220608/covid-breakthrough-infections-more-likely-in-people-living-with-hiv20:59
BrainstormUpdates for Morocco: +938 cases, +7765 tests since a day ago21:01
BrainstormNew from COVID on Twitter: Gunhild Alvik Nyborg (@GANyborg): The intensive research into long COVID may start to "trickle down" to other conditions"We conclude that ME/CFS is accompanied by substantial and measurable changes in coagulability, platelet hyper activation, and fibrinaloid microclot formation" #MECFS1/ [... want %more?] → https://twitter.com/GANyborg/status/153463368086546022522:37
LjL<Brainstorm> New from CIDRAP: Moderna's Omicron-targeted booster shot shows promise: Lisa Schnirring | News Editor | CIDRAP News Jun 08, 2022 Moderna says its new 2-strain vaccine boosts Omicron antibody response eightfold. → https://www.cidrap.umn.edu/news-perspective/2022/06/modernas-omicron-targeted-booster-shot-shows-promise22:45
LjL"An unnamed official said the government would redirect $5 billion in existing funds to buy new vaccines if they become available and will repurpose $5 billion in previously approved aid to buy treatments, including Pfizer's COVID-19 antiviral drug Paxlovid." :\22:46
LjL"The $10 billion shift in resources will come from programs to ensure a supply of COVID-19 tests, efforts to stockpile ventilators and personal protective equipment, and Department of Health and Human Services research programs on coronavirus vaccines and treatments, according to the Post."22:47
LjLall-in on vaccines all over again! Tuvix ^ whoever22:47
BrainstormNew from CIDRAP: Moderna's Omicron-targeted booster shot shows promise: Lisa Schnirring | News Editor | CIDRAP News Jun 08, 2022 Moderna says its new 2-strain vaccine boosts Omicron antibody response eightfold. → https://www.cidrap.umn.edu/news-perspective/2022/06/modernas-omicron-targeted-booster-shot-shows-promise22:47
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): "Our results underscore the potential importance of selective pressures such as the use of monoclonal antibodies — in combination with the lack of an effective endogenous immune response--in promoting escape mutations"nejm.org/doi/full/10.10… in 5 [... want %more?] → https://twitter.com/EricTopol/status/153464258874505216023:17

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