| Brainstorm | Updates for Guatemala: +3158 cases, +13 deaths since 22 hours ago | 00:03 |
|---|---|---|
| Brainstorm | Updates for India: +16048 cases since 23 hours ago — Mozambique: +92 cases, +769 tests since a day ago | 01:00 |
| Brainstorm | Updates for Zimbabwe: +173 cases, +7 deaths, +5080 tests since a day ago | 02:02 |
| Brainstorm | New from BBC Health: Polio: Virus found in London prompts misleading vaccine claims: What do these cases really tell us about the virus, which hasn't spread in the UK for decades? → https://www.bbc.co.uk/news/health-61915794 | 02:14 |
| Brainstorm | New from r/COVID19: COVID19: COVID-19 linked to acute kidney injury → https://old.reddit.com/r/COVID19/comments/vk29oo/covid19_linked_to_acute_kidney_injury/ | 02:53 |
| Brainstorm | Updates for Slovakia: +424 cases since 23 hours ago — Canada: +2275 cases since 23 hours ago | 02:59 |
| Brainstorm | New from COVID on Twitter: Michael Lin, MD PhD (@michaelzlin): And now the positive press coverage on Omicron boosters (would have been nice to have this earlier):reuters.com/business/healt… → https://twitter.com/michaelzlin/status/1540516316120903680 | 04:11 |
| ferret | does anyone know if paxlavid can cure a cold | 04:59 |
| Brainstorm | Updates for Mexico: +17432 cases, +42 deaths, +29793 tests since a day ago — Thailand: +2236 cases, +16 deaths since a day ago — Bolivia: +1186 cases since 22 hours ago | 05:10 |
| Brainstorm | New from r/Science: science: Flu vaccination linked to 40% reduced risk of Alzheimer’s disease, study finds → https://old.reddit.com/r/science/comments/vk5ckk/flu_vaccination_linked_to_40_reduced_risk_of/ | 05:29 |
| -Bridgestorm- 🌍 زلزله! Zəlzələ! Earthquake! 5.6 Mb tremor, registered by EMSC,GEOFON,GFZ, with 45 reports, occurred 10 minutes ago (03:37:13 UTC), during daytime, Kīsh, Iran, Islamic Republic of (26.54, 54.21) ± 4 km likely felt 340 km away (in بندر چارک, جناح…) by 11000 people (www.seismicportal.eu) | 05:47 | |
| Brainstorm | New from This Week In Virology: TWiV 912: COVID-19 clinical update #120 with Dr. Daniel Griffin: In COVID-19 clinical update #120, Dr. Griffin discusses outcomes of SARS-CoV-2 reinfection, CDC recommendation for vaccines in young children, neurodevelopment outcomes in infants of mothers testing positive for COVID during pregnancy, [... want %more?] → https://www.microbe.tv/twiv/twiv-912/ | 06:08 |
| Brainstorm | Updates for Japan: +13337 cases, +3 deaths, +140251 tests since 10 hours ago — Germany: +89336 cases, +84 deaths since a day ago — Pakistan: +435 cases, +13644 tests since a day ago — Venezuela: +199 cases, +1 deaths since a day ago | 07:03 |
| Brainstorm | Updates for California, United States: +55657 cases, +78 deaths since a day ago — Madrid, Spain: +17313 cases, +18 deaths since 2 days ago — Minas Gerais, Brazil: +14029 cases, +99 deaths since a day ago — Missouri, United States: +9178 cases, +57 deaths since a day ago | 08:09 |
| Brainstorm | New from r/Coronavirus: Daily Discussion Thread | June 25, 2022: Please refer to our Wiki for more information on COVID-19 and our sub. You can find answers to frequently asked questions in our FAQ , where there is valuable information such as our: → https://old.reddit.com/r/Coronavirus/comments/vk979d/daily_discussion_thread_june_25_2022/ | 09:04 |
| Brainstorm | Updates for Sindh, Pakistan: +285 cases since a day ago — Islamabad, Pakistan: +50 cases, +1 deaths since a day ago | 11:04 |
| Brainstorm | New from NPR Science: Monkeypox outbreak in U.S. is bigger than the CDC reports. Testing is 'abysmal': The testing system set up by the CDC actually deters doctors from ordering a monkeypox test, and many physicians aren't familiar with the disease, resulting in too few tests and [... want %more?] → https://www.npr.org/sections/health-shots/2022/06/25/1107416457/monkeypox-outbreak-in-us | 11:09 |
| Brainstorm | New from Reddit (test): CoronaVirus_2019_nCoV: Serologic testing captures missed children at risk for long Covid → https://old.reddit.com/r/CoronaVirus_2019_nCoV/comments/vkbduf/serologic_testing_captures_missed_children_at/ | 11:37 |
| Brainstorm | New from COVID on Twitter: (translated) Tom Wenseleers (@TWenseleers): Experts: 'Give people under 60 the choice for an extra vaccination' nu.nl/coronavirus/62… via @NUnl → https://twitter.com/TWenseleers/status/1540630180607262721 | 11:47 |
| Brainstorm | Updates for Russia: +3072 cases, +61 deaths since 23 hours ago | 12:07 |
| Brainstorm | New from COVID on Twitter: stuart mcdonald (@ActuaryByDay): Another nice example of Simpson’s Paradox in the new @COVID19actuary Friday Report.Developing countries experience a fatality rates 2-3 times higher than developed countries. Nonetheless Africa (median age 20) experiences a much lower fatality rate [... want %more?] → https://twitter.com/ActuaryByDay/status/1540636609103765510 | 12:16 |
| gry | https://www.abc.net.au/news/2022-06-24/reinfection-covid-more-severe-new-variants/101178246 - why would a virus want this to happen - i thought as a virus evolves, it becomes less severe | 12:27 |
| de-facto | by which process would a virus evolve towards a certain property? | 12:57 |
| de-facto | for a certain mutation the metric of success is how well it competes with the other mutants prevalent in the same biological niche of resources (e.g. hosts with a certain type of most common immunity) | 12:58 |
| de-facto | which disadvantage in terms of viral reproduction would it mean to a new mutant if the associated disease caused by it takes a more severe progression after this mutant already passed the time window in which it would transmit to a new susceptible in a population? | 13:01 |
| de-facto | if most transmissions take place by spreading from asymptomatic or mildly symptomatic phases of disease trajectory, that window of time where carriers still are either unaware of their infectious status or are not symptomatic enough to go into isolating themselves from social contacts it only would mean a disadvantage for a mutant to cause more severe progressions if that would lead to significantly more containment efforts being implemented to | 13:03 |
| de-facto | close down transmission paths | 13:03 |
| de-facto | something that we do not really observe anymore in most western countries, hence a mutant causing more severe disease in later stages does not really have a disadvantage spreading to the next host in the early, still mildly or even asymptomatic phase, therefore there is no selection bias towards this particular property of a mutant to be a disadvantage in the one metric that counts for viruses: competitiveness in reproduction. | 13:05 |
| de-facto | https://covariants.org/shared-mutations | 13:06 |
| de-facto | %title | 13:06 |
| Brainstorm | de-facto: From covariants.org: CoVariants: Shared Mutations | 13:06 |
| de-facto | gry, as you can see in that table comparing the mutations, the Omicron variant BA.2 now gained S:L452R mutation from Delta and the characteristic S-gene dropout S:H69- and S:V70- from Alpha or BA.1 | 13:08 |
| de-facto | this resulted in the new variants BA.4 and BA.5, the second spreading now in most countries https://covariants.org/per-country rapidly increasing and possibly beginning to infect lung tissue more again | 13:10 |
| de-facto | so possibly gaining S:L452R may have enabled it to cause a bit more severe progressions and S:H69- and S:V70- enables specific PCR tests (those testing for S-gene dropout or SGTF) to identify that BA.4/5 from BA.2 | 13:11 |
| de-facto | also it seems it can infect recoveries from BA.1/2 just fine, hence it can cause reinfections | 13:12 |
| de-facto | that results in increasing daily infection numbers in many countries as well as viral load in test samples going up (causing PCR tests to already reach detection threshold with fewer cycles, hence lower CT values) | 13:13 |
| de-facto | which is not good news, because more viral load also means carriers potentially are more infectious by shedding more virions onto their environment | 13:14 |
| de-facto | its causing a "summer wave" in many countries, nothing too dramatic, but unfortunately also not a pause from COVID | 13:15 |
| de-facto | in the northern hemisphere ofc | 13:15 |
| Brainstorm | New from Reddit (test): 25/06/22 - ZOE COVID-19 Study Update: 2,749,215 people are currently predicted to have symptomatic COVID-19 in the UK, up by 96,668. Yesterday was 2,652,547 (+4%) and last Saturday was 2,002,718 (+37%). → https://old.reddit.com/r/CoronavirusUK/comments/vkd88e/250622_zoe_covid19_study_update/ | 13:52 |
| Brainstorm | Updates for UAE: +1692 cases, +1 deaths, +293159 tests since 23 hours ago — Slovenia: +775 cases since 23 hours ago | 13:59 |
| Brainstorm | New from Reddit (test): nCoV: Global COVID Cases For 25JUN22 → https://old.reddit.com/r/nCoV/comments/vkdhzg/global_covid_cases_for_25jun22/ | 14:02 |
| Brainstorm | Updates for Croatia: +1087 cases, +1 deaths, +2898 tests since a day ago — Philippines: +777 cases, +20971 tests since 23 hours ago | 15:08 |
| Brainstorm | New from r/Coronavirus: Coronavirus: COVID-19 vaccines saved 20M lives in 1st year, scientists say → https://old.reddit.com/r/Coronavirus/comments/vkedxy/covid19_vaccines_saved_20m_lives_in_1st_year/ | 15:10 |
| Brainstorm | New from Reddit (test): nCoV: Beijing Reopens Schools for More Students as Covid Cases Ease | 25JUN22 → https://old.reddit.com/r/nCoV/comments/vkfd9u/beijing_reopens_schools_for_more_students_as/ | 15:49 |
| Brainstorm | New from Reddit (test): nCoV: New study shows an increased prevalence of headaches in adolescents during COVID-19 pandemic | 24JUN22 → https://old.reddit.com/r/nCoV/comments/vkfjng/new_study_shows_an_increased_prevalence_of/ | 15:58 |
| Brainstorm | Updates for Hong Kong: +1794 cases since 23 hours ago | 16:05 |
| Brainstorm | New from Reddit (test): CoronaVirus_2019_nCoV: Cases climb in Southeast Asia and Europe in latest week as BA.4 and BA.5 subvariants take hold - MarketWatch → https://old.reddit.com/r/CoronaVirus_2019_nCoV/comments/vkfp4v/cases_climb_in_southeast_asia_and_europe_in/ | 16:07 |
| Brainstorm | New from Reddit (test): nCoV: Beyond the spike: New antibody analysis predicts severe COVID-19 outcomes | 24JUN22 → https://old.reddit.com/r/nCoV/comments/vkfyv7/beyond_the_spike_new_antibody_analysis_predicts/ | 16:17 |
| Brainstorm | New from Reddit (test): nCoV: Covid 19 Omicron outbreak: 24 deaths and 8638 new cases over past two days | 24JUN22 → https://old.reddit.com/r/nCoV/comments/vkgcnl/covid_19_omicron_outbreak_24_deaths_and_8638_new/ | 16:36 |
| Brainstorm | New from Reddit (test): nCoV: Book Excerpt: How Coronavirus Could Be Part Of China’s Biological Attack Programme | 25JUN22 → https://old.reddit.com/r/nCoV/comments/vkgei5/book_excerpt_how_coronavirus_could_be_part_of/ | 16:46 |
| Brainstorm | New from COVID on Twitter: Eric Topol (@EricTopol): This consistent finding reflects the immune escape property of BA.4/5. We don't yet know the clinical impact of the Omicron booster, directed vs BA.1, which is genetically and antigenically distant/distinct from BA.4/5 pic.twitter.com/96WEPvloaL → https://twitter.com/EricTopol/status/1540707437425991680 | 16:56 |
| Brainstorm | New from LitCovid: (news): Neutropenia in Patients With Clozapine-Treated Schizophrenia: An Effect of Clozapine or a Consequence of SARS-CoV-2 Infection? A Systematic Review. → https://www.ncbi.nlm.nih.gov/research/coronavirus/publication/35749754 | 17:06 |
| Brainstorm | Updates for Greece: +12082 cases, +8 deaths since a day ago — Iraq: +1345 cases since a day ago | 17:07 |
| Brainstorm | New from r/COVID19: COVID19: Pfizer and BioNTech Announce Omicron-Adapted COVID-19 Vaccine Candidates Demonstrate High Immune Response Against Omicron → https://old.reddit.com/r/COVID19/comments/vkiosm/pfizer_and_biontech_announce_omicronadapted/ | 18:32 |
| Brainstorm | New from COVID on Twitter: Scott Gottlieb, MD (@ScottGottliebMD): Spread of this deadly strain of meningitis, which has significant potential to widen, should prompt universities with dorms - and other places where people congregate in close contact - to take steps to protect those settings, including through [... want %more?] → https://twitter.com/ScottGottliebMD/status/1540735278524121089 | 18:42 |
| Brainstorm | Updates for Italy: +56873 cases, +40 deaths, +258456 tests since 23 hours ago — Myanmar: +15 cases since a day ago | 19:06 |
| Brainstorm | New from Contagion Live: “Long COVID” Caused by High Levels of Virus-Specific T Cells: Patients suffering from post-acute sequelae of COVID-19, or “long COVID,” had virus-specific T cells that were more than 100 times higher than patients who fully recovered from COVID-19 infection. → https://www.contagionlive.com/view/-long-covid-caused-by-high-levels-of-virus-specific-t-cells | 19:11 |
| Brainstorm | New from COVID on Twitter: Carl T. Bergstrom (@CT_Bergstrom): In January and February 2020, COVID spread undetected in the community in the US, because of a shortage of tests, and administration that publicly stated they didn’t want testing, and eligibility guidelines that precluded detecting community spread. [... want %more?] → https://twitter.com/CT_Bergstrom/status/1540743219054403591 | 19:50 |
| Brainstorm | Updates for Chile: +12637 cases, +39 deaths since a day ago — Morocco: +3235 cases, +1 deaths, +14881 tests since 23 hours ago — Albania: +289 cases since 23 hours ago — Montenegro: +184 cases, +788 tests since 21 hours ago | 20:03 |
| Brainstorm | New from COVID on Twitter: Eric Topol (@EricTopol): Genetic, antigenic distances, & fitness of Omicron subvariants. While BA.4/5 are becoming dominant around the world, we are several months behind the virus's evolutionUnfathomable there isn't a full court press for a pan-β-coronavirus vaccine (The is more fit [... want %more?] → https://twitter.com/EricTopol/status/1540756670602543104 | 20:09 |
| Brainstorm | New from COVID on Twitter: Michael Lin, MD PhD (@michaelzlin): Okay Reuters, why the free ad for Pfizer yesterday when the data were Moderna's?Anyway today Pfizer also announced their Omicron boosters work better on Omicron than original boosters.Results and news reaction as predicted since Jan in this [... want %more?] → https://twitter.com/michaelzlin/status/1540761925822214144 | 20:29 |
| Brainstorm | Updates for Lithuania: +93064 cases since 9 hours ago | 20:59 |
| Brainstorm | New from COVID on Twitter: Florian Krammer (@florian_krammer): OK, here is the Moderna bivalent vaccine (wild type plus BA.1) preprint. twitter.com/medrxivpreprin… → https://twitter.com/florian_krammer/status/1540773778065596416 | 21:19 |
| Brainstorm | New from COVID on Twitter: Eric Topol (@EricTopol): US Covid hospitalizations are continuing to increase as the BA.4/5 variants become dominant, fortunately at a far lesser slope than BA.1 pic.twitter.com/U8IbIrMKuw → https://twitter.com/EricTopol/status/1540778452432760835 | 21:39 |
| Brainstorm | Updates for Israel: +6950 cases, +5 deaths since 21 hours ago | 22:02 |
| Brainstorm | New from COVID on Twitter: Jonathan Cedernaes (@JCedernaes): Promising (prelim.) data for #Moderna's bivalent mRNA vaccine:"Additionally, #mRNA-1273.214 50-μg induced a potent neutralizing antibody response against omicron subvariants BA.4/BA.5 and higher binding antibody responses against alpha, beta, gamma, [... want %more?] → https://twitter.com/JCedernaes/status/1540783516530638849 | 22:07 |
| Brainstorm | New from COVID on Twitter: Gunhild Alvik Nyborg (@GANyborg): As per the theory:"the 43,375 people who tested positive had a 3.5 times increased risk of being diagnosed with Alzheimer's disease, 2.6 times with Parkinson's disease,2.7 times with ischemic stroke and a 4.8 times increased with intracerebral [... want %more?] → https://twitter.com/GANyborg/status/1540789323615707137 | 22:17 |
| Brainstorm | New from COVID on Twitter: Scott Gottlieb, MD (@ScottGottliebMD): For context, WHO didn’t declare COVID a PHEIC until January 30th, 2020; after the epidemic in Wuhan was already in decline and the virus had spread to Europe, the U.S. and beyond. twitter.com/drtedros/statu… → https://twitter.com/ScottGottliebMD/status/1540799369577828353 | 22:55 |
| Brainstorm | Updates for Canada: +902 cases, +1 deaths since 23 hours ago | 23:04 |
| Brainstorm | New from Reddit (test): nCoV: Nearly 1 in 5 Adults Who Had COVID Have Lingering Symptoms, US Study Finds → https://old.reddit.com/r/nCoV/comments/vko9rr/nearly_1_in_5_adults_who_had_covid_have_lingering/ | 23:44 |
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