| Brainstorm | New from WebMD: Expert Answers to Key Questions About COVID Vaccines for Kids: Infectious disease doctors address safety, efficacy, dosing, and other concerns regarding authorized COVID-19 vaccines for youngest Americans. → https://www.webmd.com/vaccines/covid-19-vaccine/news/20220628/expert-answers-to-key-questions-about-covid-vaccines-for-kids | 00:17 |
|---|---|---|
| Brainstorm | New from Novavax: (news): Novavax COVID-19 Data Presented at FDA VRBPAC Meeting Demonstrates Broad Antibody Responses to Both Prototype and Omicron-Specific Variants → https://ir.novavax.com/2022-06-28-Novavax-COVID-19-Data-Presented-at-FDA-VRBPAC-Meeting-Demonstrates-Broad-Antibody-Responses-to-Both-Prototype-and-Omicron-Specific-Variants | 00:46 |
| Brainstorm | New from WebMD: FDA Panel Backs Adding Omicron Component to COVID Boosters: The FDA’s advisers on vaccines deliberated Tuesday on what direction the agency should give drugmakers about future modifications to their COVID shots to address changes in the virus. → https://www.webmd.com/vaccines/covid-19-vaccine/news/20220628/fda-panel-backs-adding-omicron-component-to-covid-boosters | 01:06 |
| Brainstorm | Updates for Brazil: +70038 cases, +242 deaths since 22 hours ago — India: +15825 cases since 17 hours ago — Guatemala: +3838 cases, +12 deaths since a day ago — Bahrain: +1834 cases, +7586 tests since a day ago | 01:08 |
| Brainstorm | New from Reddit (test): CoronaVirus_2019_nCoV: Evusheld significantly prevented COVID-19 disease progression or death in TACKLE Phase III treatment trial → https://old.reddit.com/r/CoronaVirus_2019_nCoV/comments/vn15tz/evusheld_significantly_prevented_covid19_disease/ | 01:44 |
| LjL | de-facto, ↑↑↑ | 01:45 |
| LjL | do you know this drug? | 01:45 |
| LjL | ah it's two monoclonals | 01:46 |
| LjL | but it's being tested for mild disease with chance of progression | 01:46 |
| LjL | not quite a pill to pop, though | 01:47 |
| Brainstorm | New from ##covid-19 Zotero group: Efficacy and safety of intramuscular administration of tixagevimab–cilgavimab for early outpatient treatment of COVID-19 (TACKLE): a phase 3, randomised, double-blind, placebo-controlled trial: Type Journal Article Author Hugh Montgomery Author F. D. Richard Hobbs Author Francisco [... want %more?] → https://www.zotero.org/groups/covid_links/items/WPLJRPCE | 01:54 |
| de-facto | %title https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(22)00180-1/fulltext | 02:00 |
| de-facto | seems so yeah | 02:00 |
| Brainstorm | de-facto: From www.thelancet.com: The Lancet | The best science for better lives | 02:00 |
| de-facto | question is how conserved the epitope is they dock onto | 02:00 |
| de-facto | surely widespread use would cerate some selection pressure, hence combining two antibodies mitigate that to some degree, yet real question would be how well the potential of evasive mutants could be suppressed by choosing an epitope that would put some significant (lethal?) fitness cost on such an evasive mutant | 02:07 |
| de-facto | LjL, a problem with monoclonals is that they must be given IV hence require to visit a hospital, so its not a "fire and forget pill" to give people for use at home | 02:13 |
| de-facto | but they can be given as "passive immunization" e.g. when an outbreak happens in an elderly home everyone could be given monoclonals in advance as post exposure prophylaxis | 02:14 |
| Brainstorm | New from COVID on Twitter: Florian Krammer (@florian_krammer): I was too busy today to follow all of VRBPAC. Was there any comment about the Pfizer bivalent versus monovalent Omicron vaccine? Any data from Moderna about their monovalent Omicron vaccine? → https://twitter.com/florian_krammer/status/1541938863509315587 | 02:23 |
| Brainstorm | Updates for Slovakia: +728 cases since 14 hours ago — Canada: +3210 cases since 5 hours ago | 03:00 |
| Brainstorm | New from COVID on Twitter: Michael Lin, MD PhD (@michaelzlin): FDA has the data on how well Pfizer and Moderna's BA1 vax do on BA2 and BA4, so they may decide with that. If FDA wants a change to BA4±2, they can guide that BA1 may be non-approvable due to failure to address the medical need, whereas BA4±2 might [... want %more?] → https://twitter.com/michaelzlin/status/1541947788270784513 | 03:02 |
| Brainstorm | New from NPR Science: The U.S. will offer nearly 300,000 doses of monkeypox vaccine in the coming weeks: The Department of Health and Human Services will make 296,000 doses available in the coming weeks, and expects a total of 1.6 million doses to be available in the U.S. by the end of [... want %more?] → https://www.npr.org/2022/06/28/1108466255/us-to-expand-availability-monkeypox-vaccine | 04:00 |
| Brainstorm | Updates for Panama: +1989 cases, +4 deaths, +15381 tests since a day ago — Kenya: +439 cases, +3937 tests since a day ago — Syria: +2 cases since a day ago | 04:03 |
| Brainstorm | New from Politico: Freedom comes at a price — European voters may not want to pay it: Amid the political turbulence caused by the pandemic and the war in Ukraine, incumbent governments are in trouble. → https://www.politico.eu/article/eu-freedom-france-marine-le-pen-boyko-borissov-andrej-babis-comes-european-voters-populism-crisis/ | 04:10 |
| Brainstorm | Updates for Mexico: +20959 cases, +42 deaths, +37771 tests since 22 hours ago — South Korea: +10437 cases, +7 deaths since 23 hours ago — Thailand: +2569 cases, +14 deaths since 22 hours ago | 05:00 |
| de-facto | %title https://www.nature.com/articles/s41467-022-31097-7 | 05:06 |
| Brainstorm | de-facto: From www.nature.com: A global lipid map reveals host dependency factors conserved across SARS-CoV-2 variants | Nature Communications | 05:06 |
| Brainstorm | New from BMJ Open: Experiences of and response to the COVID-19 pandemic at private retail pharmacies in Kenya: a mixed-methods study: Objectives To assess experiences of and response to the COVID-19 pandemic at community pharmacies in Kenya. Design, setting and participants This was a mixed-methods study conducted from [... want %more?] → http://bmjopen.bmj.com/cgi/content/short/12/6/e058688 | 05:18 |
| Brainstorm | Updates for St. Kitts and Nevis: +27 cases since a day ago | 06:02 |
| Brainstorm | Updates for Germany: +133950 cases, +175 deaths since a day ago | 07:05 |
| Brainstorm | Updates for California, United States: +50753 cases, +76 deaths since a day ago — Bavaria, Germany: +19630 cases, +25 deaths since a day ago — Switzerland: +17871 cases since 15 hours ago — Lazio, Italy: +11171 cases, +5 deaths since a day ago | 08:08 |
| Brainstorm | New from MedicineNet: (news): Paxlovid Cuts Omicron Hospitalizations by 45% → http://www.medicinenet.com/script/main/art.asp | 08:47 |
| Brainstorm | Updates for Japan: +12778 cases, +102177 tests since 13 hours ago — Bolivia: +1402 cases since a day ago | 09:04 |
| Brainstorm | New from r/Coronavirus: Daily Discussion Thread | June 29, 2022: Please refer to our Wiki for more information on COVID-19 and our sub. You can find answers to frequently asked questions in our FAQ , where there is valuable information such as our: → https://old.reddit.com/r/Coronavirus/comments/vn9hc2/daily_discussion_thread_june_29_2022/ | 09:07 |
| Brainstorm | Updates for Kazakhstan: +115 cases since 12 hours ago | 10:07 |
| Brainstorm | New from Politico: Aid and development: Commission says it can’t find von der Leyen-Pfizer texts — and doesn’t need to → https://www.politico.eu/article/commission-says-cant-find-ursula-von-der-leyen-pfizer-text-doesnt-need-to/ | 10:24 |
| Brainstorm | New from COVID on Twitter: (translated) Marc Veldhoen (@Marc_Veld): But the message now remains: Immunity after vaccination (and infection) lasts and will prevent serious illness in most. But, spread must be contained, masks and distance, testing and isolation after contact/symptoms play an important role here! For each!22/22 → https://twitter.com/Marc_Veld/status/1542072895458918401 | 11:13 |
| Brainstorm | New from BMJ: Triage in general practice: key hurdles to overcome: I agree that triage cannot fix the imbalance between supply and demand in general practice,1 but I hope that it can bring improvements to how we use precious resources. Several factors need to be... → http://www.bmj.com/content/377/bmj.o1585.short | 11:22 |
| Brainstorm | Updates for Russia: +3028 cases, +54 deaths since a day ago | 12:06 |
| Brainstorm | New from The Lancet (Online): [Comment] A new paradigm is needed for financing the pandemic fund: At the second meeting of the G20 finance ministers and central bank governors on April 20, 2022, the G20, under the presidency of Indonesia, agreed to establish a new financial mechanism: a [... want %more?] → https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(22)01239-9/fulltext | 12:11 |
| Brainstorm | New from Science-Based Medicine: COVID Associated With Neurodegenerative Disorders: COVID infection has been associated with an increased risk of neurodegenerative and neurovascular disease - another reason to keep our eye on this serious illness. The post first appeared on Science-Based [... want %more?] → https://sciencebasedmedicine.org/covid-associated-with-neurodegenerative-disorders/ | 13:29 |
| Brainstorm | Updates for Croatia: +1197 cases, +1 deaths, +3516 tests since 23 hours ago — Malta: +570 cases, +2003 tests since 23 hours ago — Albania: +550 cases, +1 deaths since 22 hours ago | 14:05 |
| Brainstorm | New from r/COVID19: COVID19: New tools help assess COVID-19 risks: COVID-Taser website predicts likelihood of severe illness or death → https://old.reddit.com/r/COVID19/comments/vnef3f/new_tools_help_assess_covid19_risks_covidtaser/ | 14:18 |
| Brainstorm | New from Reddit (test): nCoV: Global COVID Cases For 29JUN22 → https://old.reddit.com/r/nCoV/comments/vneivc/global_covid_cases_for_29jun22/ | 14:27 |
| Brainstorm | Updates for Indonesia: +2149 cases, +3 deaths, +80020 tests since a day ago — UAE: +1769 cases, +2 deaths, +192567 tests since a day ago | 15:01 |
| Brainstorm | New from COVID on Twitter: Marc Veldhoen (@Marc_Veld): Mice immunized with nanoparticles co-displaying spike receptor-binding domains from 8 sarbecoviruses efficiently elicit cross-reactive anti-sarbecovirus antibodies. pic.twitter.com/Pc3jP5hXoU → https://twitter.com/Marc_Veld/status/1542132824416915457 | 15:17 |
| Brainstorm | New from EMA: Human medicine assessment reports: (news): Human medicines European public assessment report (EPAR): Rotarix, rotavirus vaccine, live, Immunization;Rotavirus Infections, Date of authorisation: 21/02/2006, Revision: 40, Status: Authorised → https://www.ema.europa.eu/en/medicines/human/EPAR/rotarix | 15:37 |
| Brainstorm | New from EMA: Human medicine assessment reports: (news): Human medicines European public assessment report (EPAR): HBVaxPro, hepatitis B vaccine (recombinant DNA), Hepatitis B;Immunization, Date of authorisation: 27/04/2001, Revision: 30, Status: Authorised → https://www.ema.europa.eu/en/medicines/human/EPAR/hbvaxpro | 15:46 |
| Brainstorm | New from Reddit (test): CoronaVirus_2019_nCoV: What is Evusheld? People in Massachusetts can get at-home injection to help prevent COVID → https://old.reddit.com/r/CoronaVirus_2019_nCoV/comments/vng8tm/what_is_evusheld_people_in_massachusetts_can_get/ | 15:56 |
| Brainstorm | Updates for Hong Kong: +2004 cases since a day ago — Qatar: +707 cases since a day ago | 16:04 |
| Brainstorm | Updates for Iraq: +2628 cases, +2 deaths since 23 hours ago — Bangladesh: +2241 cases, +14712 tests since a day ago — Iran: +441 cases since a day ago | 17:01 |
| Brainstorm | New from Contagion Live: Why Aren't People With COVID-19 Symptoms Getting Tested?: Many people who self-report as symptomatic for COVID-19 neglect to get tested, largely citing not knowing where to go for a test as the reason. → https://www.contagionlive.com/view/why-aren-t-people-with-covid-19-symptoms-getting-tested- | 17:14 |
| Brainstorm | New from LitCovid: (news): Four Cases of Papilledema in COVID-19 Multisystem Inflammatory Syndrome in Children. → https://www.ncbi.nlm.nih.gov/research/coronavirus/publication/35763214 | 17:24 |
| Brainstorm | Updates for Italy: +95455 cases, +60 deaths since 22 hours ago — Kosovo: +177 cases since 23 hours ago — St. Kitts and Nevis: +30 cases since 12 hours ago | 18:03 |
| Brainstorm | New from COVID on Twitter: Eric Topol (@EricTopol): Covid and the catnature.com/articles/d4158… → https://twitter.com/EricTopol/status/1542182935356313600 | 18:33 |
| Brainstorm | Updates for Ireland: +13229 cases, +30 deaths since 6 days ago — Serbia: +876 cases since 22 hours ago | 19:00 |
| Brainstorm | New from StatNews: Opinion: FDA: Don’t rush a move to change the Covid-19 vaccine composition: A multibillion-dollar decision to launch a vaccine based wholly or in part on the BA.1, BA.4, or BA.5 Omicron sequences need not be rushed. Using an additional week or two… → https://www.statnews.com/2022/06/29/fda-dont-rush-to-change-covid-19-vaccine-composition/ | 19:04 |
| Brainstorm | New from COVID on Twitter: Gunhild Alvik Nyborg (@GANyborg): Thorough study finds aerosol particle emission increases moderately up to an moderate exercise intensity, exponentially at higher intensities. On average emission increases 132-fold from 580 particles/min at rest to 76,200 particles/min during max exercise [... want %more?] → https://twitter.com/GANyborg/status/1542200698401689607 | 19:45 |
| Brainstorm | New from COVID on Twitter: Gunhild Alvik Nyborg (@GANyborg): The study randomized participants to train at a fitness center or alone during partial lockdown spring 2020, at a time when the virus was almost fully stopped in Norway. The aim was to see if training at fitness center was risky or not. Almost 1900 were [... want %more?] → https://twitter.com/GANyborg/status/1542204272812621825 | 19:54 |
| LjL | %print https://twitter.com/EricTopol/status/1542150602922278914 | 19:59 |
| Brainstorm | LjL, It says: Eric Topol on Twitter: "It's long overdue. No details. But a step in the right direction. https://t.co/LEBV9Wd6Ba https://t.co/tAtHB1MreZ" / Twitter | 19:59 |
| LjL | %print https://pbs.twimg.com/media/FWbRyNDWIAAm7FH?format=jpg&name=900x900 | 19:59 |
| Brainstorm | LjL, It says: BioNTech, Pfizer to start testing universal vaccine for coronaviruses Ludwig Burger + June 29, 20226:45 AM PDTLast Updated 32 min ago June 29 (Reuters) - Germany's BioNTech (22UAy.DE), Pfizer's (PFE.N) partner in COVID-19 vaccines, said the two companies would start tests on humans of next-generation shots that protect against a wide variety of coronaviruses in the [... want %more?] | 20:00 |
| Brainstorm | New from COVID on Twitter: Gunhild Alvik Nyborg (@GANyborg): The results were touted by the researchers as evidence that "it is completely safe to exercise at fitness centers" and the study was used as argument to re-open fitness centers during the lockdown phase 8/ nrk.no/norge/forskere… pic.twitter.com/YvS6erdNag → https://twitter.com/GANyborg/status/1542206463375966208 | 20:04 |
| Brainstorm | Updates for Malaysia: +2605 cases, +5 deaths since a day ago — Canada: +13 deaths since 23 hours ago | 20:09 |
| Brainstorm | New from COVID on Twitter: Gunhild Alvik Nyborg (@GANyborg): It can also stand as an example of how science has been used & misused to weigh in on political/public health issues during the pandemic, and why it's been so hard for the public to follow the science. Such results have been utilized & spread extensively for [... want %more?] → https://twitter.com/GANyborg/status/1542209411913056256 | 20:23 |
| Brainstorm | New from r/COVID19: COVID19: Fast detection of SARS-CoV-2 variants including Omicron using one-step RT-PCR and Sanger sequencing → https://old.reddit.com/r/COVID19/comments/vnmg80/fast_detection_of_sarscov2_variants_including/ | 20:43 |
| Brainstorm | Updates for Turkey: +26635 cases, +17 deaths since a day ago — Mozambique: +94 cases, +1148 tests since a day ago | 21:11 |
| Brainstorm | New from COVID on Twitter: Scott Gottlieb, MD (@ScottGottliebMD): 100 million doses of ACAM2000 doesn’t meet the CDC’s claim that “The Strategic National Stockpile (SNS) has stockpiled enough smallpox vaccine to vaccinate every person in the United States,” a pledge that President Bush made in 2002 [... want %more?] → https://twitter.com/ScottGottliebMD/status/1542223905162665992 | 21:13 |
| Brainstorm | New from COVID on Twitter: Scott Gottlieb, MD (@ScottGottliebMD): There’s another 90 million doses of a second, much older vaccine that was manufactured in the 1950s and remained frozen. While this second vaccine is unapproved, it could be used in an emergency. It was reported to have been tested for potency [... want %more?] → https://twitter.com/ScottGottliebMD/status/1542227559013916674 | 21:32 |
| de-facto | %title https://investors.biontech.de/news-releases/news-release-details/pfizer-and-biontech-announce-omicron-adapted-covid-19-vaccine | 21:37 |
| Brainstorm | de-facto: From investors.biontech.de: Pfizer and BioNTech Announce Omicron-Adapted COVID-19 Vaccine Candidates Demonstrate High Immune Response Against Omicron | BioNTech | 21:37 |
| de-facto | %title https://www.reuters.com/business/healthcare-pharmaceuticals/biontech-pfizer-starting-testing-universal-coronavirus-vaccine-h2-2022-06-29/ | 21:38 |
| Brainstorm | de-facto: From www.reuters.com: BioNTech, Pfizer to start testing universal vaccine for coronaviruses | Reuters | 21:38 |
| de-facto | %title https://investors.modernatx.com/news/news-details/2022/Moderna-Announces-Bivalent-Booster-mRNA-1273.214-Demonstrates-Potent-Neutralizing-Antibody-Response-Against-Omicron-Subvariants-BA.4-And-BA.5/default.aspx | 21:39 |
| Brainstorm | de-facto: From investors.modernatx.com: Moderna Announces Bivalent Booster mRNA-1273.214 Demonstrates Potent Neutralizing Antibody Response Against Omicron Subvariants BA.4 And BA.5 | 21:39 |
| de-facto | %title https://investors.modernatx.com/news/news-details/2022/Moderna-Announces-Omicron-Containing-Bivalent-Booster-Candidate-mRNA-1273.214-Demonstrates-Superior-Antibody-Response-Against-Omicron/default.aspx | 21:40 |
| Brainstorm | de-facto: From investors.modernatx.com: Moderna Announces Omicron-Containing Bivalent Booster Candidate mRNA-1273.214 Demonstrates Superior Antibody Response Against Omicron | 21:40 |
| Brainstorm | New from COVID on Twitter: Gunhild Alvik Nyborg (@GANyborg): Pfizer/BioNTech to start tests on “T-cell-enhancing shots, designed to primarily protect against severe disease if the virus becomes more dangerous, and pan-coronavirus shots that protect against the broader family of viruses and its mutations”. [... want %more?] → https://twitter.com/GANyborg/status/1542230946145075201 | 21:42 |
| Brainstorm | New from COVID on Twitter: Scott Gottlieb, MD (@ScottGottliebMD): Doses of a much older smallpox vaccine were discarded in 2008cidrap.umn.edu/news-perspecti… pic.twitter.com/FCzm4TPgNL → https://twitter.com/ScottGottliebMD/status/1542231605288239104 | 21:52 |
| Brainstorm | Updates for France: +124724 cases since a day ago — Mauritania: +108 cases since a day ago | 22:01 |
| Brainstorm | New from COVID on Twitter: Scott Gottlieb, MD (@ScottGottliebMD): In recent days CDC officials have used 100 million doses in describing the scope of existing smallpox vaccine stockpile. cnbc.com/2022/06/04/the… pic.twitter.com/aLpJhG5ihu → https://twitter.com/ScottGottliebMD/status/1542233947282735105 | 22:02 |
| Brainstorm | New from CIDRAP: Global COVID cases rise as BA.4 and BA.5 expand: Lisa Schnirring | News Editor | CIDRAP News Jun 29, 2022 COVID-19 cases jumped 18% last week and are at their highest levels since April, the WHO says. → https://www.cidrap.umn.edu/news-perspective/2022/06/global-covid-cases-rise-ba4-and-ba5-expand | 22:11 |
| Brainstorm | New from COVID on Twitter: Marc Veldhoen (@Marc_Veld): Augmented neutralisation resistance of emerging omicron subvariants BA.2.12.1, BA.4, and BA.5Confirmation that conserved epitopes represent an effective treatment/vaccine for patients with COVID-19, irrespective of the infecting omicron [... want %more?] → https://twitter.com/Marc_Veld/status/1542240698866466816 | 22:21 |
| Brainstorm | New from COVID on Twitter: Scott Gottlieb, MD (@ScottGottliebMD): The New York Times similarly reports that there are only 100 million doses of the newer, ACAM2000 smallpox vaccine in the current strategic stockpilenytimes.com/2022/06/03/hea… pic.twitter.com/04idDnDbwF → https://twitter.com/ScottGottliebMD/status/1542241225457156096 | 22:30 |
| Brainstorm | New from BioNTech: Pfizer and BioNTech Announce New Agreement with U.S. Government to Provide Additional Doses of COVID-19 Vaccine: 105 million 30 µg, 10 µg and 3 µg doses to be delivered into Q4 2022, with an option for the U.S. Government [... want %more?] → https://investors.biontech.de/news-releases/news-release-details/pfizer-and-biontech-announce-new-agreement-us-government-provide | 22:50 |
| Brainstorm | New from CIDRAP: Maternal deaths climbed 33% during COVID-19: Jim Wappes | Editorial Director | CIDRAP News Jun 29, 2022 Deaths may have been directly related to COVID-19 or exacerbated by COVID-19 or by healthcare disruptions, study authors say. → https://www.cidrap.umn.edu/news-perspective/2022/06/maternal-deaths-climbed-33-during-covid-19 | 23:00 |
| Brainstorm | Updates for Montenegro: +437 cases, +4 deaths, +980 tests since 2 days ago | 23:04 |
| Brainstorm | New from COVID on Twitter: Eric Topol (@EricTopol): Real-world vaccine effectiveness (VE) in children age 5-11 during the Omicron wave in Israel; ~95,000 kids vaccinated with matched controlsVE 48% vs symptomatic Covid after 2nd dosenejm.org/doi/full/10.10… @NEJM @ClalitHealth @ClalitResearch @RanBalicer pic.twitter.com/koaIEZM0tG → https://twitter.com/EricTopol/status/1542252466980327424 | 23:09 |
| Brainstorm | New from COVID on Twitter: Michael Lin, MD PhD (@michaelzlin): Notably Fauci was double boosted just a week before infection; he was as protected as he could be with currently approved vaccines. Emphasis on currently and approved. → https://twitter.com/michaelzlin/status/1542255431359180801 | 23:19 |
| Brainstorm | New from COVID on Twitter: Eric Topol (@EricTopol): How long to people shed culturable #SARSCoV2 virus after Omicron infections?Many >5 days (*median 5*, interquartile range 3 to 9 days), which goes against the CDC guideline of 5 days after symptom onset or + PCR testnejm.org/doi/full/10.10… pic.twitter.com/voQadCXxbA → https://twitter.com/EricTopol/status/1542255901452603392 | 23:29 |
| Brainstorm | New from Reddit (test): Covid2019: COVID cases surge again in Europe as Moderna says its booster candidate protects against BA.4 and BA.5 omicron subvariants → https://old.reddit.com/r/Covid2019/comments/vnqw7y/covid_cases_surge_again_in_europe_as_moderna_says/ | 23:38 |
| Brainstorm | New from Ars Technica: Science: Fauci reports COVID rebound, says it’s “much worse” than initial illness → https://arstechnica.com/?p=1863606 | 23:58 |
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