libera/##covid-19/ Tuesday, 2022-07-12

BrainstormNew from Reddit (test): CoronaVirus_2019_nCoV: COVID-19 viral load up 630 percent in Houston-area wastewater → https://old.reddit.com/r/CoronaVirus_2019_nCoV/comments/vwuexx/covid19_viral_load_up_630_percent_in_houstonarea/00:02
BrainstormUpdates for South Africa: +706 cases, +4 deaths since 3 days ago — Canada: +1016 cases since 3 hours ago00:11
BrainstormNew from The Lancet (Online): [Correspondence] Perilous two-tier COVID-19 global vaccine roll-out: “The essence of global health equity is the idea that something so precious as health might be viewed as a right.”1 This beautiful sentiment, a legacy of the inspirational Paul Farmer, [... want %more?] → https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(22)01284-3/fulltext00:40
BrainstormUpdates for South Korea: +37323 cases, +7 deaths since 23 hours ago01:01
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): US @WHCOVIDResponse planning to make 2nd booster shots available for age < 50, all adultswashingtonpost.com/health/2022/07… by @ddiamond @lauriemcginley2 @bylenasun  w/ @PeterHotez Better than discarding tens of millions of doses pic.twitter.com/zoXpfG3f9y → https://twitter.com/EricTopol/status/154663071329368883201:08
BrainstormNew from COVID on Twitter: Scott Gottlieb, MD (@ScottGottliebMD): Would patients at risk from bad COVID outcomes be better served boosting with a bivalent BA.1 vaccine right now, if it was available, rather than another dose of the ancestral strain vaccine? Would a BA.1 based booster now provide more protection [... want %more?] → https://twitter.com/ScottGottliebMD/status/154664217666219212801:55
LjL%print https://twitter.com/BinitaKane/status/154610909346675097602:00
BrainstormLjL, It says: Binita Kane on Twitter: "Wow, just stumbled across this tweet from April 2020! #prophetic. If only the world had listened back then. #TeamClots" / Twitter02:00
LjLlinked tweet:02:00
LjL%print https://twitter.com/giovannilandoni/status/125124658101956198402:00
BrainstormLjL, It says: Giovanni Landoni, MD on Twitter: "After treating >800 severe #COVID19 patients (>110 in ICU), we suggest #MicroCLOTS as the new name for severe disease. We hypothesise that ➡️ alveolar viral damage ↪️ inflammatory reaction ↪️ microvascular pulmonary thrombosis ↪️ MOF/death https://t.co/Zlsua04KQP #FOAMed #FOAMcc https://t.co/RSmA1KRi7i" / Twitter02:00
LjLalso, can't trace the study, but02:01
LjL%print https://twitter.com/mildanalyst/status/154644290230537420802:01
BrainstormLjL, It says: Pandemic News on Twitter: "Well well well BA.5 more damaging to lungs than earlier subvariants Just like Delta, BA.5 enters cells via the TMPRSS2 pathway and is more likely to infect the lower lung. https://t.co/jCAGTDMa1Y" / Twitter02:01
LjLTopol has an updated article on BA.5 https://erictopol.substack.com/p/ba5-chapter-202:02
LjLmaybe it's time we started paying attention to it being a new variant rather than being fooled by this trick of it just being a subvariant of omicron and "carry on folks, nothing to see here" ;(02:02
BrainstormUpdates for Bulgaria: +1308 cases, +5 deaths, +7367 tests since a day ago — Azerbaijan: +344 cases, +2 deaths since 7 days ago — Syria: +6 cases since 2 days ago02:03
LjLOf all therapeutic antibodies tested, we observed a 14.3-fold reduction using Evusheld and 16.8 reduction using Sotrovimab when neutralising a Clade A versus BA.5 isolate.02:05
BrainstormNew from ##covid-19 Zotero group: SARS-CoV-2 Omicron BA.5: Evolving tropism and evasion of potent humoral responses and resistance to clinical immunotherapeutics relative to viral variants of concern.: Type Report Author Anupriya Aggarwal Author Anouschka Akerman Author Vanessa Milogiannakis Author Mariana Ruiz Silva [... want %more?] → https://www.zotero.org/groups/covid_links/items/VZGWSKTK02:14
de-facto%title https://www.medrxiv.org/content/10.1101/2022.07.07.22277128v102:30
Brainstormde-facto: From www.medrxiv.org: SARS-CoV-2 Omicron BA.5: Evolving tropism and evasion of potent humoral responses and resistance to clinical immunotherapeutics relative to viral variants of concern. | medRxiv02:30
BrainstormUpdates for Canada: +1033 cases since 6 hours ago03:05
BrainstormNew from COVID on Twitter: Caitlin Rivers, PhD (@cmyeaton): Our last couple flu seasons have been quiet thanks to covid measures. Some epis have been worried that we are due for a bad flu year bc of a buildup of the susceptible population. Now Australia is having a notable season-- early, high peak and high burden in [... want %more?] → https://twitter.com/cmyeaton/status/154666766214257868803:38
BrainstormUpdates for Australia: +46093 cases, +40 deaths since 23 hours ago — Nova Scotia, Canada: +7193 cases, +7 deaths since 30 days ago — Newfoundland and Labrador, Canada: +1532 cases, +6 deaths since a month ago — Haiti: +141 cases since 4 days ago04:01
BrainstormUpdates for Bolivia: +3037 cases, +1 deaths since 20 hours ago05:10
BrainstormNew from r/COVID19: COVID19: Combined Nasal, Oropharyngeal Povidone Iodine Plus Glycyrrhizic Acid Sprays, Accelerate Clinical and Laboratory Recovery and Reduces Household Transmission of SARS-CoV-2: A Randomized Placebo-Controlled Clinical Trial → https://old.reddit.com/r/COVID19/comments/vx1350/combined_nasal_oropharyngeal_povidone_iodine_plus/05:50
BrainstormUpdates for Germany: +154729 cases, +165 deaths since 23 hours ago06:00
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): According to the Walgreen's index, the US is at 41% test positivity, higher than Omicron BA.1 and since this tracking was establishedwalgreens.com/businesssoluti…18% at @CDCgov covid.cdc.gov/covid-data-tra…Also seetwitter.com/nataliexdean/s… pic.twitter.com/45PnoRo93E → https://twitter.com/EricTopol/status/154670568962763571306:08
BrainstormUpdates for Peru: +8061 cases, +10 deaths, +24828 tests since 23 hours ago07:02
BrainstormNew from Il Sole 24 Ore: (translated) Covid still bites, but home treatments (Usca and antivirals) remain at stake: At least half of the regions have not renewed the Usca, the special teams of doctors and nurses who have been on the front line since March 2020 → https://www.ilsole24ore.com/art/il-covid-morde-ancora-ma-cure-casa-usca-e-antivirali-restano-palo-AEPV4dlB07:23
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): @jburnmurdoch @fernandaedi @SofiaWisewyn @phylogenomics @SarahNev Yes, It’s even worse here now with waning and poor booster uptake, relying on Omicron infection cross-immunity to hold up the wall → https://twitter.com/EricTopol/status/154673641701908480308:09
BrainstormUpdates for Sicily, Italy: +49264 cases since a day ago — North Rhine-Westphalia, Germany: +31576 cases, +21 deaths since 3 days ago — Bavaria, Germany: +29634 cases, +20 deaths since 3 days ago — Baden-Wurttemberg, Germany: +20710 cases, +12 deaths since a day ago08:10
BrainstormNew from MedicineNet: (news): AHA News: Being Vaccinated May Lower Stroke Risk in Adults With Flu-Like Illnesses → http://www.medicinenet.com/script/main/art.asp08:47
BrainstormNew from r/Coronavirus: Daily Discussion Thread | July 12, 2022: Please refer to our Wiki for more information on COVID-19 and our sub. You can find answers to frequently asked questions in our FAQ , where there is valuable information such as our: → https://old.reddit.com/r/Coronavirus/comments/vx4wex/daily_discussion_thread_july_12_2022/09:06
BrainstormNew from BMJ: Expert wisdom on prostate cancer testing not evident in NHS commissioning guidance: In their editorial on diagnosing prostate cancer in asymptomatic patients, Bradley and colleagues highlight both the need for caution in the use of screening tests and the implications for the almost... → http://www.bmj.com/content/378/bmj.o1705.short10:02
BrainstormUpdates for Taiwan: +31273 cases, +60 deaths, +71536 tests since 23 hours ago10:09
BrainstormUpdates for Tamil Nadu, India: +2448 cases since a day ago — Odisha, India: +572 cases since a day ago — Chhattisgarh, India: +360 cases, +1 deaths since a day ago — Himachal Pradesh, India: +244 cases, +1 deaths since a day ago11:11
BrainstormNew from BMJ: COVID-19: Clinical prediction models for mortality in patients with covid-19: external validation and individual participant data meta-analysis → http://www.bmj.com/content/378/bmj-2021-069881.short11:27
BrainstormNew from COVID on Twitter: Marc Veldhoen (@Marc_Veld): Inhalable dry powder mRNA vaccines basedon extracellular vesiclesInteresting development to deliver vaccines via inhalationdoi.org/10.1016/j.matt… → https://twitter.com/Marc_Veld/status/154678830696861286411:36
BrainstormUpdates for Slovenia: +2365 cases since 23 hours ago — Poland: +2034 cases, +5 deaths since 23 hours ago12:01
BrainstormNew from r/Science: science: Aggressive behaviour of anti-vaxxers and their toxic replies in social media . The reply of anti-vaxxers can work as a targeted attack to influence vaccine belief and may provoke anxiety about vaccination in other clusters, because replies can reach [... want %more?] → https://old.reddit.com/r/science/comments/vx77kl/aggressive_behaviour_of_antivaxxers_and_their/12:25
BrainstormNew from StatNews: STAT+: Verve Therapeutics begins human tests of first ‘base editor,’ aiming at heart disease: The first patient ever has been dosed with a kind of gene-editing treatment known as a base editor, a newer way of utilizing CRISPR for gene editing. → https://www.statnews.com/2022/07/12/verve-therapeutics-begins-human-tests-of-first-base-editor/12:43
BrainstormNew from Reddit (test): nCoV: Moderna to make two different omicron boosters: one for US, another for UK, EU | 11JUL22 → https://old.reddit.com/r/nCoV/comments/vx8b1i/moderna_to_make_two_different_omicron_boosters/12:53
BrainstormNew from Reddit (test): nCoV: NSW COVID reinfection period reduced from 12 weeks to four | 12JUL22 → https://old.reddit.com/r/nCoV/comments/vx8cnk/nsw_covid_reinfection_period_reduced_from_12/13:02
BrainstormUpdates for Estonia: +3583 cases, +9 deaths since 6 days ago — Indonesia: +3361 cases, +8 deaths since 23 hours ago — New Caledonia: +1325 cases, +1 deaths since 7 days ago — Nepal: +144 cases since 21 hours ago13:03
BrainstormNew from Reddit (test): nCoV: Moscow Sees Rise in Covid Cases, Recommends Mask Wearing | 12JUL22 → https://old.reddit.com/r/nCoV/comments/vx8ncr/moscow_sees_rise_in_covid_cases_recommends_mask/13:11
BrainstormNew from Reddit (test): 12/07/22 - ZOE COVID-19 Study Update: 4,377,078 people are currently predicted to have symptomatic COVID-19 in the UK, up by 80,475. Yesterday was 4,296,603 (+2%) and last Tuesday was 3,856,169 (+14%). → https://old.reddit.com/r/CoronavirusUK/comments/vx8tay/120722_zoe_covid19_study_update/13:40
BrainstormUpdates for Kazakhstan: +483 cases since 15 hours ago — Liechtenstein: +85 cases since 4 days ago — France: +1189 cases since 16 hours ago14:11
BrainstormNew from BMJ: Covid-19: Parts of England see hospital admissions more than double in two weeks: Some areas of England have seen the number of patients in hospital who have tested positive for covid-19 more than double in the past two weeks, latest figures show.Overall, the number of people in... → http://www.bmj.com/content/378/bmj.o1723.short14:28
BrainstormNew from Reddit (test): nCoV: Global COVID Cases For 12JUL22 → https://old.reddit.com/r/nCoV/comments/vxacko/global_covid_cases_for_12jul22/14:47
BrainstormNew from COVID on Twitter: Megan Molteni (@MeganMolteni): Base editing, invented less than 7 years ago, moves into its first tests in humans, for heart disease. A look at the science and ethics, with @matthewherper ( )statnews.com/2022/07/12/ver… → https://twitter.com/MeganMolteni/status/154684531862446080015:35
BrainstormNew from BMJ: Diagnosing prostate cancer at a curable stage means providing PSA tests to asymptomatic patients: Bradley and colleagues’ editorial1 reiterates outdated uncertainties around prostate specific antigen (PSA) based screening for prostate cancer and fails to highlight advances in UK clinical... → http://www.bmj.com/content/378/bmj.o1714.short15:54
BrainstormUpdates for Iran: +3588 cases, +7 deaths since a day ago — Hong Kong: +2769 cases, +1 deaths since 23 hours ago — UAE: +1554 cases, +123037 tests since a day ago16:03
BrainstormNew from COVID on Twitter: SARS News Network (SNN)     (@COVIDnewsfast): pic.twitter.com/oq4wTDO2DN → https://twitter.com/COVIDnewsfast/status/154686407917994393616:32
BrainstormNew from StatNews: Health: Citing risk from Omicron variant BA.5, White House urges Americans to get Covid-19 boosters → https://www.statnews.com/2022/07/12/omicron-variant-ba-5-risk-white-house-urges-boosters/16:52
BrainstormUpdates for Switzerland: +37748 cases, +11 deaths, +130291 tests since 6 days ago — North Macedonia: +510 cases, +2 deaths, +1489 tests since 19 hours ago16:59
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): Just published @ScienceMagazine are 2 more broad neutralizing antibodies with "unprecedented breadth" that add to a long list of well-suited candidates/basis for a universal pan-β-coronavirus vaccine science.org/doi/10.1126/sc…science.org/doi/10.1126/sc… [... want %more?] → https://twitter.com/EricTopol/status/154687734272260096017:30
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): What happens if we don't take much more aggressive steps now towards nasal spray and variant-proof vaccines when an even worse #SARSCoV2 immune evasive variant shows up in the months ahead? → https://twitter.com/EricTopol/status/154688033926755942417:40
BrainstormNew from r/Science: science: Pig-Heart Transplants in Two Brain-Dead People Offer Chance to Improve Tests for Pig Viruses — The Wall Street Journal → https://old.reddit.com/r/science/comments/vxeakb/pigheart_transplants_in_two_braindead_people/17:50
ublxpuh17:57
ublxmust have been an interesting ethics review17:57
BrainstormNew from StatNews: Pharma: STAT+: ‘Eye-opening’: The pandemic accelerated antimicrobial resistance across the U.S. → https://www.statnews.com/pharmalot/2022/07/12/antibiotic-resistance-antimicrobial-covid19-hospitals-cdc/18:00
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): BA.5 is now >65% of new infections in the United States covid.cdc.gov/covid-data-tra… and we even got a @CDCgov public warning about it pic.twitter.com/E4E0lTm3Tc → https://twitter.com/EricTopol/status/154689117273122816218:19
BrainstormNew from r/COVID19: COVID19: SARS-CoV-2 S1 Protein Persistence in SARS-CoV-2 Negative Post-Vaccination Individuals with Long COVID/ PASC-Like Symptoms → https://old.reddit.com/r/COVID19/comments/vxfep2/sarscov2_s1_protein_persistence_in_sarscov2/18:38
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): I'm getting a lot of "To boost or not to boost" questions, so here's a Table with some recommendations now that boosters will soon be available to all adults. There are many uncertainties for waiting, and the original vaccine boost provides an extra layer of [... want %more?] → https://twitter.com/EricTopol/status/154690025131901337618:58
BrainstormUpdates for Italy: +144058 cases, +157 deaths since 23 hours ago — Serbia: +2050 cases, +3 deaths, +10966 tests since 23 hours ago — Montenegro: +569 cases, +1 deaths, +1780 tests since a day ago19:04
BrainstormUpdates for Spain: +59226 cases, +244 deaths since 4 days ago — Sri Lanka: +23 cases since 22 hours ago20:00
BrainstormNew from WebMD: Coming Soon: More Breathable, More Comfortable Face Masks: Entrepreneurs, universities and corporations are competing to take home $150,000 as one of the two top winners of the federal Mask Innovation Challenge. → https://www.webmd.com/lung/news/20220712/coming-soon-more-breathable-more-comfortable-face-masks20:24
BrainstormUpdates for Japan: +64288 cases, +21 deaths since 14 hours ago — Canada: +11836 cases since 20 hours ago21:09
BrainstormNew from CIDRAP: Study: Kids spent 20% less time in physical activity amid COVID-19: Mary Van Beusekom | News Writer | CIDRAP News Jul 12, 2022 The drop grew to 25% when the study period was longer. → https://www.cidrap.umn.edu/news-perspective/2022/07/study-kids-spent-20-less-time-physical-activity-amid-covid-1921:31
BrainstormNew from Reddit (test): CoronaVirus_2019_nCoV: Wichita State extends free COVID testing → https://old.reddit.com/r/CoronaVirus_2019_nCoV/comments/vxjnu5/wichita_state_extends_free_covid_testing/21:40
BrainstormNew from COVID on Twitter: Tom Wenseleers (@TWenseleers): Quite remarkable that more than a year after the 1st Covid vaccine was approved we still don't have any adapted vaccine for any of the variants that arose since. Despite the fact that mass producing adapted mRNA vaccines takes no longer than ca. 3 months. → https://twitter.com/TWenseleers/status/154694235487101337621:50
BrainstormUpdates for France: +182444 cases since 7 hours ago — Albania: +1215 cases, +2 deaths since 21 hours ago — Comoros: +48 cases since 8 days ago22:05
BrainstormNew from Reddit (test): CoronaVirus_2019_nCoV: CEPI partners with Codiak BioSciences to develop broadly protective Betacoronavirus vaccine - 05 Jul 2022 → https://old.reddit.com/r/CoronaVirus_2019_nCoV/comments/vxkequ/cepi_partners_with_codiak_biosciences_to_develop/22:18
BrainstormNew from COVID on Twitter: Marc Veldhoen (@Marc_Veld): Moderna to make two different omicron boosters: one for US, another for UK, EUModerna says its BA.1-targeting vaccine boosts protection against BA.4/5. arstechnica.com/science/2022/0… → https://twitter.com/Marc_Veld/status/154695317668703436922:27
BrainstormNew from Politico: Coronavirus: Borrell’s adviser pushes China’s contested claim that COVID came from US → https://www.politico.eu/article/josep-borrell-jeffrey-sachs-adviser-china-disinformation-us-covid-origin/22:37
BrainstormNew from WebMD: 'Don't Panic': U.S. Has Tools to Manage BA.5, White House Says: The BA.5 Omicron subvariant is dominating now and accounts for 65% – or about two-thirds – of the virus causing COVID-19 in the United States, federal officials said on Tuesday. Although no evidence yet points to BA.5 [... want %more?] → https://www.webmd.com/lung/news/20220712/us-tools-manage-ba5-white-house22:46
LjLwhat is this nonsense?!22:56
LjL%title https://arstechnica.com/science/2022/07/moderna-to-make-two-different-omicron-boosters-one-for-us-another-for-uk-eu/22:56
BrainstormLjL: From arstechnica.com: Moderna to make two different omicron boosters: one for US, another for UK, EU | Ars Technica22:56
LjLthey will only give a BA.4 and BA.5 booster to the US? when in fact we're the ones the wave has just started to hit?22:56
LjLde-facto, is this what you were talking about earlier wrt using old BA.1 for vaccine?22:58
de-factopartly yeah, i just want an up-to-date multivalent booster available on all markets as "pan" in pandemic means "all" (not restricted to some region) people23:03
LjLbut the article says the price to pay will be later availability23:04
LjLmid-fall, instead of august23:04
de-factoi dont get it why it should make sense to develop BA.1 + Wuhan-Hu-1 for EU and BA.4/5 + Wuhan-Hu-1 for US23:04
LjLis it a price worth paying? the wave is going strong23:04
de-factoit also should include all the other variants that were able to spread widely, e.g. Delta, Alpha etc23:05
de-factowhy only bivalent? we have the signatures for all the VoCs23:06
de-factomake the immune system aware of the entire multitude of advantageous mutations that allowed the pathogen to reach wide spread23:06
BrainstormUpdates for Ukraine: +88363 cases, +307 deaths since 4 months ago — Crimea Republic, Ukraine: +26633 cases, +462 deaths since 4 months ago — Sevastopol, Ukraine: +11857 cases, +309 deaths since 4 months ago23:07
de-factowow hmm23:07
LjLuh, are these numbers from Ukraine or from Russia23:07
LjL%cases ukraine23:08
BrainstormLjL: Ukraine has had 5.1 million confirmed cases (12.2% of all people) and 112766 deaths (2.2% of cases; 1 in 371 people) as of a minute ago. 19.5 million tests were done (0.5 per capita, 26.3% positive). 14.7 million were vaccinated (35.2%). +88363 cases, +307 deaths since 4 months ago. See https://covid19.rnbo.gov.ua/23:08
LjLhttps://covid19.rnbo.gov.ua/ still doesn't open for me23:10
LjLthe numbers Brainstorm gives are coming from Covidly23:10
LjLno idea who Covidly decided to trust23:10
BrainstormNew from CIDRAP: White House officials push boosters as BA.5 surge intensifies: Lisa Schnirring | News Editor | CIDRAP News Jul 12, 2022 BA.4 and BA.5 subvariants now make up about 81% of circulating viruses in the US. → https://www.cidrap.umn.edu/news-perspective/2022/07/white-house-officials-push-boosters-ba5-surge-intensifies23:24
Timvdede-facto: FYI, I did a RAT today and was ever so slightly still positive23:34
TimvdeFaintest red line I could imagine23:34
dTalhad you consumed any beverages?23:38
dTalacidic drinks will do that23:38
dTalbest thing is to drink some water, wait an hour, and test again23:38
TimvdeNo23:38
TimvdeBut I am still in isolation, to be clear :P23:39
dTaleven a faint line is a definite positive, in the absence of a contaminating substance such as acid23:39
TimvdeI know23:40
TimvdeBut de-facto asked if I still tested positive on a RAT23:40
TimvdeI probably got infected on the 1st of July, 11 days ago23:40
de-factointeresting, so yeah your viral load is then barely above the RATs threshold23:40
de-factoso if you do a test directly in the morning, before drinking something or brushing teeth it may get the full load accumulated during the night sleep23:41
de-factoi mean that is to be expected from the antigenic dynamic shown by the graph in that challenge trial i guess23:41
de-factohttps://www.nature.com/articles/s41591-022-01780-9/figures/223:42
de-factoso you are well within the expectation value (although you are vaccinated and most likely got Omicron, they used naive with some older variant)23:43

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