libera/##covid-19/ Wednesday, 2022-07-13

BrainstormUpdates for Malawi: +49 cases, +2 deaths, +866 tests since a day ago00:03
de-facto%title v00:19
Brainstormde-facto, the command line provided is invalid00:19
de-factomeh00:19
de-facto%title https://www.nature.com/articles/s41564-022-01149-100:19
Brainstormde-facto: From www.nature.com: Omicron: a shift in the biology of SARS-CoV-2 | Nature Microbiology00:19
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): Thinking about the overlap of Americans who are still Covid cautious and those paying close attention to the Jan 6th hearings...... and those ignoring both → https://twitter.com/EricTopol/status/154698157484699648100:21
de-facto%title https://www.nature.com/articles/s41564-022-01143-700:22
Brainstormde-facto: From www.nature.com: SARS-CoV-2 Omicron is an immune escape variant with an altered cell entry pathway | Nature Microbiology00:22
de-facto%title https://www.biorxiv.org/content/10.1101/2022.07.12.499603v100:24
Brainstormde-facto: From www.biorxiv.org: Enhanced innate immune suppression by SARS-CoV-2 Omicron subvariants BA.4 and BA.5 | bioRxiv00:24
BrainstormNew from Reddit (test): nCoV: Whilst you were distracted by Boris resigning, the UK Gov. | 12JUL22 → https://old.reddit.com/r/nCoV/comments/vxnew8/whilst_you_were_distracted_by_boris_resigning_the/00:31
BrainstormNew from Reddit (test): CoronaVirus_2019_nCoV: Universal COVID-19 vaccine candidate to enter clinical trials: candidates will include T-cell enhancing shots and pan-coronavirus shots that “protect against the broader family of viruses and its mutations.” → https://old.reddit.com/r/CoronaVirus_2019_nCoV/comments/vxnnb5/universal_covid19_vaccine_candidate_to_enter/00:40
BrainstormUpdates for Brazil: +64048 cases, +288 deaths since 23 hours ago — India: +22119 cases since 23 hours ago — Bahrain: +1322 cases, +3 deaths, +4973 tests since 23 hours ago — Mozambique: +90 cases, +811 tests since 23 hours ago00:59
BrainstormNew from r/COVID19: COVID19: The unnaturalistic fallacy: COVID-19 vaccine mandates should not discriminate against natural immunity → https://old.reddit.com/r/COVID19/comments/vxogdg/the_unnaturalistic_fallacy_covid19_vaccine/01:27
-Bridgestorm- 🌕 Temblor? Sismo? Earthquake? Maybe strong tremor, with 40 reports, 14 early, possibly occurred 3 minutes ago (23:36:40 UTC), during a full moon night, La Capilla, Peru (-16.79, -71.32) ± 83 km likely felt 270 km away (Twitter)01:40
-Bridgestorm- 🏠 Temblor! Sismo! Earthquake! 5.5 M tremor, registered by Sismos_Peru_IGP,alomax, with 47 reports, 6 early, occurred 5 minutes ago (23:36:12 UTC), during a full moon night, Quequeña, Peru (-16.68, -71.43) ± 20 km, ↓10 km likely felt 290 km away (in Arequipa…) by 844000 people → https://twitter.com/Sismos_Peru_IGP/status/1547003255728885764 (Twitter)01:42
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol):  Another undesirable feature of the BA.5 variant: Enhanced antagonism of innate immunity not seen in prior Omicron variants (BA.1, BA.2) biorxiv.org/content/10.110… pic.twitter.com/nQ9e9vs6fa → https://twitter.com/EricTopol/status/154700499002731315201:55
BrainstormUpdates for Guyana: +184 cases, +1 deaths since 23 hours ago02:01
BrainstormNew from BBC Health: Covid: 3m adults still unvaccinated in England: Some are vulnerable people who could get extremely sick if they were to catch Covid, warn experts. → https://www.bbc.co.uk/news/health-6213854502:33
BrainstormUpdates for Norway: +411 cases since a day ago — Barbados: +297 cases, +1108 tests since a day ago — Canada: +13833 cases since 23 hours ago03:10
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): New study from Qatar on BA.4/5 reinfection—Protection of a previous infection against BA.4/BA.5 was lower than that against BA.1/BA.2 (> immune escape)—Pre-Omicron infections offered little protection, but BA.1/BA.2 infections high, ~80% VE [... want %more?] → https://twitter.com/EricTopol/status/154702349305257984003:11
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): This is better than what might have been predicted with the relatively narrow observed immune response from BA.1., BA.2. Bodes well for some added protection vs BA.5 from a BA.1 booster → https://twitter.com/EricTopol/status/154703378344190361603:49
BrainstormNew from COVID on Twitter: Trevor Bedford (@trvrb): @TWenseleers @alexselby1770 @Mike_Honey_ This is causing our inference of BA.2.75 Rt to dive here: github.com/blab/rt-from-f…. I don’t have an easy explanation for what’s going on with this aspect. → https://twitter.com/trvrb/status/154703524300511232203:59
BrainstormUpdates for Australia: +41632 cases, +58 deaths since 23 hours ago — Belize: +560 cases since 5 days ago — Fr. Polynesia: +170 cases since 22 hours ago04:00
BrainstormNew from COVID on Twitter: Tom Wenseleers (@TWenseleers): @trvrb @alexselby1770 @Mike_Honey_ Thanks for this! Weird indeed! Could it be that BA.2.75 is still very localised? I see that for Maharashtra (n=84) most BA.2.75 seqs are from Aurangabad (n=42) or Nagpur (n=36) and in those two districts cases are [... want %more?] → https://twitter.com/TWenseleers/status/154704177363303628804:17
BrainstormNew from COVID on Twitter: Tom Wenseleers (@TWenseleers): @trvrb @JPWeiland @alexselby1770 @Mike_Honey_ The transmission advantage I calculated from early Delta / B.1.617.2 seqs from India at the time matched perfectly with a later published analysis based on genomes from randomly sampled cases... So doubt if [... want %more?] → https://twitter.com/TWenseleers/status/154704883180365824104:45
BrainstormUpdates for South Korea: +40248 cases, +12 deaths since a day ago — Mexico: +36334 cases, +92 deaths, +56180 tests since 23 hours ago — Tunisia: +20903 cases, +75 deaths, +39854 tests since 6 days ago — Thailand: +2391 cases, +25 deaths since 23 hours ago05:09
BrainstormNew from Reddit (test): CoronaVirus_2019_nCoV: Stunning spread of BA.5 shows why this California COVID wave is so different: "A lot of people were recently infected can probably get the virus, again, in three or four weeks, versus the old days, where they have a [... want %more?] → https://old.reddit.com/r/CoronaVirus_2019_nCoV/comments/vxt4p4/stunning_spread_of_ba5_shows_why_this_california/05:23
BrainstormUpdates for Guatemala: +6621 cases, +23 deaths since a day ago06:05
BrainstormNew from Reddit (test): CoronaVirus_2019_nCoV: Long COVID patients are seeking experimental 'blood washing' treatment abroad, investigation finds → https://old.reddit.com/r/CoronaVirus_2019_nCoV/comments/vxupo3/long_covid_patients_are_seeking_experimental/06:48
BrainstormUpdates for Bolivia: +3801 cases, +3 deaths since a day ago — Germany: +127611 cases, +104 deaths since a day ago07:01
BrainstormNew from Reddit (test): Covid2019: One in eight US deaths from 2020–21 came from COVID-19. Millions of survivors reeling from distinctly difficult grief → https://old.reddit.com/r/Covid2019/comments/vxuqmy/one_in_eight_us_deaths_from_202021_came_from/07:45
BrainstormUpdates for California, United States: +61620 cases, +74 deaths since 23 hours ago — Baden-Wurttemberg, Germany: +20725 cases, +9 deaths since 23 hours ago — Lombardy, Italy: +20201 cases, +15 deaths since 23 hours ago — Campania, Italy: +18299 cases, +16 deaths since 23 hours ago08:10
BrainstormNew from Reddit (test): CoronavirusUK: Covid: 3m adults still unvaccinated in England → https://old.reddit.com/r/CoronavirusUK/comments/vxvbyb/covid_3m_adults_still_unvaccinated_in_england/08:24
BrainstormUpdates for Czechia: +1987 cases, +6 deaths since a day ago — Cambodia: +16 cases since 23 hours ago09:00
BrainstormNew from r/Coronavirus: Daily Discussion Thread | July 13, 2022: Please refer to our Wiki for more information on COVID-19 and our sub. You can find answers to frequently asked questions in our FAQ , where there is valuable information such as our: → https://old.reddit.com/r/Coronavirus/comments/vxwv7x/daily_discussion_thread_july_13_2022/09:01
BrainstormUpdates for Taiwan: +29861 cases, +49 deaths, +64959 tests since 23 hours ago10:02
BrainstormUpdates for Hungary: +8036 cases, +35 deaths since 6 days ago — Gujarat, India: +577 cases, +2 deaths since 23 hours ago — Telangana, India: +562 cases since 23 hours ago — Bihar, India: +436 cases, +1 deaths since 23 hours ago11:05
TimvdeWhy are BA.4 and BA.5 listed in the same column on Covariants? https://covariants.org/shared-mutations11:07
TimvdeThey aren't 100% the same, right? Otherwise, why split them up?11:07
de-factoTimvde, you can look up all the lineages on https://cov-lineages.org/lineage_list.html (they include links to their creation threats on github)11:17
de-factohttps://github.com/cov-lineages/pango-designation/issues/51711:17
BrainstormNew from EMA: Human medicine assessment reports: (news): Human medicines European public assessment report (EPAR): Nuvaxovid, COVID-19 Vaccine (recombinant, adjuvanted), COVID-19 virus infection, Date of authorisation: 20/12/2021, Revision: 3, Status: Authorised → https://www.ema.europa.eu/en/medicines/human/EPAR/nuvaxovid11:22
BrainstormNew from r/Science: science: Pandemic’s impact on volunteer health care workers. Most experienced low to mild symptoms of burnout, but a significant number met the clinical criteria for PTSD. The strongest predictor of burnout, was avoidant emotional coping, such as [... want %more?] → https://old.reddit.com/r/science/comments/vxzdge/pandemics_impact_on_volunteer_health_care_workers/12:29
BrainstormNew from PubMed: Organ transplantation using COVID-19 positive deceased donors: The COVID-19 pandemic has influenced organ transplantation decision making. Opinions regarding the utilization of COVID-19 donors is mixed. We hypothesize that COVID-19 infection of deceased solid organ transplant donors does not affect recipient [... want %more?] → https://pubmed.ncbi.nlm.nih.gov/35822320/13:06
BrainstormUpdates for Russia: +3929 cases, +42 deaths since a day ago13:10
BrainstormNew from r/Science: science: CDC: Impact on Antimicrobial Resistance, Special Report 2022, concludes that the threat of antimicrobial-resistant infections is not only still present but has gotten worse—with resistant hospital-onset infections and deaths both increasing at [... want %more?] → https://old.reddit.com/r/science/comments/vy0lac/cdc_impact_on_antimicrobial_resistance_special/13:54
BrainstormUpdates for Indonesia: +3822 cases, +12 deaths since a day ago — UAE: +1522 cases, +1 deaths, +156396 tests since 22 hours ago — Qatar: +863 cases since 23 hours ago14:06
BrainstormNew from COVID on Twitter: (translated) Marc Veldhoen (@Marc_Veld): Look if you don't even understand that you always have white blood cells and antibodies in your blood, that white blood cells are not part of a transfusion and have no idea about the many vaccines; but you are a conspiracy and populist scary you say [... want %more?] → https://twitter.com/Marc_Veld/status/154719211153519411214:23
BrainstormNew from BMJ: Why are vaccination rates lower in low and middle income countries, and what can we do about it?: Covid-19 vaccine distribution has brought global inequities in healthcare access into sharp relief. In the first six months of vaccine distribution, over 90% of all doses were given to residents of... → http://www.bmj.com/content/378/bmj-2021-069506.short14:42
BrainstormUpdates for Nepal: +177 cases since a day ago15:08
BrainstormNew from COVID on Twitter: SARS News Network (SNN)     (@COVIDnewsfast): Not protecting yourself from SARS 2 is the equivalent of walking up to a beehive without any protection and beating it with a stick, and when you get stung repeatedly and or go to the hospital, being shocked that the bees did long lasting [... want %more?] → https://twitter.com/COVIDnewsfast/status/154720620077260800115:11
LjLsuch quality feeds need to be upgraded to ##covid-ticker15:12
BrainstormNew from StatNews: Pharma: STAT+: Pharmalittle: Covid worsened antibiotic resistance; Teva and AbbVie unit settle opioid suit with San Francisco → https://www.statnews.com/pharmalot/2022/07/13/covid19-vaccines-antibiotics-opioids-cancer-novavax-teva-abbvie-illumina-antitrust/15:21
BrainstormNew from BMJ: Covid-19: MPs call for greater efforts to reach the unvaccinated and partially vaccinated: MPs have called on NHS England and the UK Health Security Agency (UKHSA) to redouble efforts to reach the almost three million adults in England who remain unvaccinated against covid-19 as well as... → http://www.bmj.com/content/378/bmj.o1743.short15:49
BrainstormNew from r/COVID19: COVID19: SARS-CoV-2 accelerated clearance using a novel nitric oxide nasal spray (NONS) treatment: A randomized trial → https://old.reddit.com/r/COVID19/comments/vy3jop/sarscov2_accelerated_clearance_using_a_novel/15:59
BrainstormUpdates for Hong Kong: +3154 cases, +2 deaths since a day ago — Saudi Arabia: +480 cases, +2 deaths, +26100 tests since a day ago — Senegal: +68 cases, +1219 tests since a day ago16:05
LjLoof, my parents just booked their 4th dose (newly available) at a place here in the alps, hope it won't be super crowded compared to Milan, and also, hope they won't get it just before an Omicron specific vaccine is released and then they're not allowed to get it16:14
LjLwhat sort of protection does a 4th dose of the original thing add, again?16:18
BrainstormNew from BMJ Open: Barriers and facilitators to implementation of a home-based cardiac rehabilitation programme for patients with heart failure in the NHS: a mixed-methods study: Objectives This study aimed to identify barriers to, and facilitators of, implementation of the Rehabilitation EnAblement in CHronic Heart [... want %more?] → http://bmjopen.bmj.com/cgi/content/short/12/7/e06022116:47
BrainstormUpdates for Iran: +5000 cases, +5 deaths since a day ago — Croatia: +1808 cases, +6 deaths, +5027 tests since a day ago17:01
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): BA.5 in New ZealandNote deaths vs Omicron BA.1 wave@OurWorldInData pic.twitter.com/MilkXb3MtD → https://twitter.com/EricTopol/status/154723335762013388817:06
BrainstormNew from WebMD: COVID Boosters Can Help People With Lupus: A new study shows people with lupus who get a COVID booster shot after full vaccination are half as likely to experience a COVID infection afterward. → https://www.webmd.com/lupus/news/20220713/covid-boosters-can-help-people-with-lupus17:26
BrainstormUpdates for Serbia: +2069 cases, +3 deaths since 22 hours ago — Cuba: +63 cases since 23 hours ago18:03
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): How #SARSCoV2 infects/affects brain astrocytespnas.org/doi/10.1073/pn… @PNASNews by @Andrews_MG @tmturkee @TheOttolab @Kriegsteinlab and colleagues pic.twitter.com/Tlk4PNMHp6 → https://twitter.com/EricTopol/status/154725044840643379218:14
de-factoLjL, afaik the 4th dose with Wuhan-Hu-1 just "revives" the previous immunity for a while (months?) but does not really broaden the antibody variety anymore (iirc)18:58
de-factoi decided for myself to wait for an updated signature of the s-protein to arrive in the market18:59
BrainstormUpdates for Singapore: +16870 cases since 18 hours ago — Ireland: +14114 cases, +35 deaths since 7 days ago — Chile: +8494 cases, +6 deaths, +50977 tests since 23 hours ago — Italy: +111591 cases, +106 deaths, +961141 tests since 23 hours ago19:00
BrainstormNew from r/Science: science: New rapid COVID test identifies variants, researchers say → https://old.reddit.com/r/science/comments/vy6vij/new_rapid_covid_test_identifies_variants/19:03
peetaurde-facto: what if waiting means 1.5 years later before there is one?19:11
LjLit won't19:12
LjLwhat if the earth is flat19:12
peetauris there a good one that is reasonably surely coming soon?19:12
peetaurif the earth is flat then 2 = 1 and the sky is not blue either19:12
LjLi'm sure anything i say will fall short of your concept of a "good one"19:12
LjLbut the ones that *are used in practice in western countries* will be out in september (the EU one) or in the fall (the US one)19:13
peetaurthat you're optimistic about....whatever19:13
de-factopeetaur, it wont take that long, there already are Omicron + Wuhan-Hu-1 biavalent vaccines in the pipeline (though i want the BA.4/5 + Wuhan-Hu-1 thing to also come on the market in EU not just US)19:15
de-factoin general the updates are way too slow, but at least they are being worked on19:16
de-factoi think this BA.4/5 wave in the summer is problematic but not going to over satuarate hospitals, at least it looks like its somewhat self limiting and peaking in countries like Portugal, but ofc it always could introduce a new mutation and things change19:17
de-factoremains to be seen, but right now i dont see a necessity for myself to boost with Wuhan-Hu-1, i rather want my immune response to contract in preparation of a proper new signature that hopefully will arrive on the market19:18
LjLsome may be inclined to sift through https://www.nakedcapitalism.com/2022/07/new-biden-ba-5-plan-openly-abandons-metrics-preventing-infection-butchers-mask-and-ventilation-policy.html so i provide it, but i'm not one of them atm19:21
BrainstormNew from COVID on Twitter: Jeffrey Barrett (@jcbarret): Good news: MRNA advancing 2 Omicron boosters. BA.1 version has + trial data already, whereas BA.5 version will need more time. Both will be better to fight whatever’s around this winter than OG vaccine. I hope they are manufacturing now in huge volumes! [... want %more?] → https://twitter.com/jcbarret/status/154726821250452685619:22
LjLde-facto, obviously it would be too big of a responsibility for me to strongly try to convince my parents to NOT get the 4th dose... but i hope they'll let them get an updated 5th without any time penalties for having gotten a 4th19:23
LjLbesides, i think doing that would undermine any willingness for people to hurry up with their vaccines19:24
de-factoi think it would be good to have a waned down immunity for the 4th dose with new s-protein signatures, because if shortly before receiving the Wuhan-hu-1 booster the new signature probably just will reactivate the previous type of immunity19:29
de-factobut that is my own speculation19:29
BrainstormNew from COVID on Twitter: Adam Kucharski (@adamjkucharski): Still seeing claims that latest COVID variants have R0 (i.e. R in fully susceptible population) of almost 20. But the same logic would lead to (incorrect) conclusion that seasonal flu has an R0 in the hundreds, if not thousands... 1/ → https://twitter.com/adamjkucharski/status/154727322838889676919:41
BrainstormUpdates for Japan: +94453 cases, +31 deaths since 22 hours ago — Malaysia: +3934 cases since 19 hours ago — Sri Lanka: +30 cases since a day ago20:02
BrainstormNew from COVID on Twitter: Michael Lin, MD PhD   (@michaelzlin): While we might believe that we generally make insufficient efforts to solve problems, it is also possible sometimes to make a problem worse by doing too much. The former should not be used to justify the latter.As true in everyday life as in pandemics. → https://twitter.com/michaelzlin/status/154728177242499481620:19
BrainstormNew from WebMD: This Teen Helped Newborns During the Early Pandemic Days: When Bryn Hammock learned that the babies in her local hospital’s NICU could only spend 2 hours a day with their parents due to COVID-19 restrictions early in the pandemic, the 18-year-old, who lives in [... want %more?] → https://www.webmd.com/parenting/baby/news/20220713/teen-helped-newborns-early-pandemic-days20:39
BrainstormUpdates for Montenegro: +566 cases, +1619 tests since a day ago21:05
BrainstormNew from CIDRAP: News Scan for Jul 13, 2022: COVID-flu co-infection New unexplained pediatric hepatitis cases Benefits of childhood vaccines CDC parechovirus warning → https://www.cidrap.umn.edu/news-perspective/2022/07/news-scan-jul-13-202221:18
BrainstormNew from COVID on Twitter: Bloom Lab (@jbloom_lab): We have a position in the Bloom lab for a research tech interested in using deep mutational scanning to study evolution of viruses including SARS-CoV-2 & influenza: careers-fhcrc.icims.com/jobs/22925/res…(And while this ad is for a tech, we are always open to [... want %more?] → https://twitter.com/jbloom_lab/status/154730077113743360021:27
BrainstormNew from CIDRAP: Study: Kids have stronger COVID-19 antibody response than adults: Mary Van Beusekom | News Writer | CIDRAP News Jul 13, 2022 Kids younger than 3 years had fivefold higher antibody levels than older participants. → https://www.cidrap.umn.edu/news-perspective/2022/07/study-kids-have-stronger-covid-19-antibody-response-adults21:56
BrainstormUpdates for Israel: +9962 cases since a day ago — France: +127642 cases since a day ago22:07
BrainstormNew from CIDRAP: Global COVID cases continue to rise as BA.5 expands: Lisa Schnirring | News Editor | CIDRAP News Jul 13, 2022 COVID-19 cases worldwide rose last week for the fifth week in a row, but deaths overall held steady. → https://www.cidrap.umn.edu/news-perspective/2022/07/global-covid-cases-continue-rise-ba5-expands22:16
BrainstormNew from COVID19 Vaccine Tracker: (translated) valerie: AnGes: AG0301-COVID19 → https://covid19.trackvaccines.org/vaccines/3/22:35
BrainstormNew from COVID19 Vaccine Tracker: valerie: Aivita Biomedical Inc: AV-COVID-19 → https://covid19.trackvaccines.org/vaccines/74/22:45
BrainstormNew from COVID19 Vaccine Tracker: valerie: ACM Biolabs: ACM-001 → https://covid19.trackvaccines.org/vaccines/207/22:55
gustikhttps://gavinpublishers.com/article/view/lubecavax-the-individual-anti-corona-vaccine-from-lubeck-primum-nihil-nocere-version-2022-06-0123:00
BrainstormUpdates for Moldova: +1852 cases, +14 deaths since 7 days ago — Canada: +3604 cases, +35 deaths since 23 hours ago23:09
LjLthat's a pretty flashy page for a journal23:11
BrainstormNew from CIDRAP: CDC report shows rise in resistant infections, deaths in first COVID year: Chris Dall | News Reporter | CIDRAP News Jul 13, 2022 "Antimicrobial resistance will not stop if we let down our guard; there is no time to waste." → https://www.cidrap.umn.edu/news-perspective/2022/07/cdc-report-shows-rise-resistant-infections-deaths-first-covid-year23:24
BrainstormNew from Novavax: (news): U.S. FDA Grants Emergency Use Authorization for Novavax COVID-19 Vaccine, Adjuvanted for Individuals Aged 18 and Over → https://ir.novavax.com/2022-07-13-U-S-FDA-Grants-Emergency-Use-Authorization-for-Novavax-COVID-19-Vaccine,-Adjuvanted-for-Individuals-Aged-18-and-Over23:43

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