libera/##covid-19/ Tuesday, 2022-07-19

BrainstormNew from The Lancet (Online): [Comment] The UK COVID-19 Inquiry must examine the foundations of pandemic decision making: As the UK Government has shifted its pandemic response to living with COVID-19,1 the long-awaited UK COVID-19 Inquiry started on June 28, 2022. Chaired by the Right [... want %more?] → https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(22)01332-0/fulltext00:38
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): We're down to 1 effective monoclonal antibody Rx"only one that has shown remarkably preserved in vitro activity against all #SARSCoV2 variants, including the omicron variant and the most recent BA.4 and BA.5 subvariants that are now becoming [... want %more?] → https://twitter.com/EricTopol/status/154916349888982630500:47
BrainstormUpdates for South Africa: +880 cases, +4 deaths, +19603 tests since 2 days ago01:10
BrainstormUpdates for Bulgaria: +2292 cases, +7 deaths since 23 hours ago — Algeria: +42 cases since a day ago02:00
BrainstormNew from Eric Topol on Substack: The pandemic and the boiling frog story: The SARS-CoV-2 variants successively keep finding new hosts, now more efficiently than they did before, despite so many prior infections, vaccinations, and boosters. Reinfections with BA.5, while poorly tracked, are likely occurring [... want %more?] → https://erictopol.substack.com/p/the-pandemic-and-the-boiling-frog02:02
BrainstormNew from r/COVID19: COVID19: Novavax NVX-COV2373 triggers potent neutralization of Omicron sub-lineages → https://old.reddit.com/r/COVID19/comments/w2edyf/novavax_nvxcov2373_triggers_potent_neutralization/02:32
BrainstormNew from COVID on Twitter: Marc Veldhoen (@Marc_Veld): Origins and Evolution of Seasonal Human CoronavirusesOC43 may have ungulate, canine, or rabbit CoV ancestors, while 229E may have origins in a bat, camel or an unsampled intermediate host. HKU1 had the earliest most recent common ancestor. biorxiv.org/content/10.110… → https://twitter.com/Marc_Veld/status/154919144674974515402:42
BrainstormUpdates for Ecuador: +7511 cases, +5 deaths since 4 days ago — Norway: +316 cases since a day ago — Syria: +20 cases since 3 hours ago — Canada: +25 cases, +28 deaths since 2 days ago03:02
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): Why the pandemic's succession of variants brings up the boiling frog metaphorerictopol.substack.com/p/the-pandemic… → https://twitter.com/EricTopol/status/154920496485713100803:39
BrainstormUpdates for Australia: +38814 cases, +58 deaths since 23 hours ago — Albania: +2815 cases, +1 deaths since 3 days ago04:05
BrainstormNew from r/COVID19: COVID19: In vitro evolution predicts emerging SARS-CoV-2 mutations with high affinity for ACE2 and cross-species binding → https://old.reddit.com/r/COVID19/comments/w2ggh2/in_vitro_evolution_predicts_emerging_sarscov2/04:07
BrainstormUpdates for South Korea: +73537 cases, +12 deaths since a day ago — Thailand: +2125 cases, +18 deaths since a day ago05:07
BrainstormUpdates for Germany: +160691 cases, +102 deaths since 3 days ago06:03
BrainstormNew from r/Science: science: Bacterial and fungal isolation from face masks under the COVID-19 pandemic → https://old.reddit.com/r/science/comments/w2ijql/bacterial_and_fungal_isolation_from_face_masks/06:46
BrainstormNew from r/Science: science: Microparticles could be used to deliver “self-boosting” vaccines → https://old.reddit.com/r/science/comments/w2k0fa/microparticles_could_be_used_to_deliver/07:53
mrdatagot my fourth jab, today. moderna07:59
BrainstormUpdates for Bavaria, Germany: +32840 cases, +15 deaths since 2 days ago — North Rhine-Westphalia, Germany: +29530 cases, +27 deaths since 2 days ago — Baden-Wurttemberg, Germany: +23901 cases since 2 days ago — Hesse, Germany: +17639 cases, +4 deaths since 2 days ago08:01
BrainstormNew from MedicineNet: (news): COVID Public Health Emergency Extended Another 3 Months → http://www.medicinenet.com/script/main/art.asp08:48
BrainstormNew from Science-Based Medicine: Chiropractic Neck Manipulations in the News: Caitlin Jensen's chiropractor called 911 when she developed alarming symptoms after neck manipulation. She had a heart attack, was pulseless for 10 minutes, and suffered traumatic brain injury. Surgeons found [... want %more?] → https://sciencebasedmedicine.org/chiropractic-neck-manipulations-in-the-news/09:07
BrainstormUpdates for Cambodia: +22 cases since a day ago09:10
BrainstormNew from BMJ: A seven point plan to suppress covid infections and reduce disruptions: It is now a year since the Westminster Government removed remaining covid protections on so-called “Freedom Day,” 19 July 2021. Since then, the emphasis has been on “personal responsibility” and “living with covid” However, in [... want %more?] → http://www.bmj.com/content/378/bmj.o1793.short09:35
BrainstormUpdates for Taiwan: +27127 cases, +37 deaths, +68703 tests since 23 hours ago — Kazakhstan: +1450 cases since a day ago — Laos: +46 cases since 23 hours ago09:59
BrainstormNew from Reddit (test): CoronavirusUK: The NHS is not living with covid, it’s dying from it → https://old.reddit.com/r/CoronavirusUK/comments/w2nkml/the_nhs_is_not_living_with_covid_its_dying_from_it/10:50
BrainstormUpdates for Tamil Nadu, India: +2223 cases since a day ago — Assam, India: +764 cases, +3 deaths since a day ago — Himachal Pradesh, India: +564 cases since a day ago — Tripura, India: +477 cases since a day ago11:02
BrainstormNew from NPR Science: Monkeypox keeps spreading. Here's what authorities are doing to stop it: Public health experts know what it takes to control a disease outbreak: access to testing and vaccines. But in the last two months of the monkeypox outbreak, the [... want %more?] → https://www.npr.org/2022/07/19/1112043780/monkeypox-keeps-spreading-heres-what-authorities-are-doing-to-stop-it11:09
BrainstormNew from EMA: What's new: Orphan: Orphan designation: Humanised anti-CD37 monoclonal antibody conjugated to maytansinoid DM1 (naratuximab emtansine), Treatment of diffuse large B-cell lymphoma, 18/07/2022, Withdrawn → https://www.ema.europa.eu/en/medicines/human/orphan-designations/eu-3-15-149411:55
BrainstormUpdates for Slovenia: +2831 cases since 23 hours ago — Afghanistan: +221 cases, +3 deaths, +1301 tests since 23 hours ago12:04
BrainstormNew from BMJ: Burnout among trainees is at all time high, GMC survey shows: Burnout among trainees and trainers has never been higher, the General Medical Council has said, warning that NHS backlogs are threatening doctors’ health and wellbeing.1The UK regulator’s annual national training survey, completed by more than 67 [... want %more?] → http://www.bmj.com/content/378/bmj.o1796.short12:24
BrainstormNew from COVID on Twitter: Marc Veldhoen (@Marc_Veld): Determinants of Spike Infectivity, Processing and Neutralization in SARS-CoV-2 Omicron subvariants BA.1 and BA.2A systematic functional analysis of Omicron Spike adaptations (no BA.5 yet).cell.com/cell-host-micr… pic.twitter.com/gAPjlTKu0K → https://twitter.com/Marc_Veld/status/154935515199514214413:31
BrainstormNew from Reddit (test): CoronaVirus_2019_nCoV: Nasal vaccines: What's the latest research on nasal vaccines for Covid? - Research on nasal vaccines is mostly in its early phases in the U.S., though many scientists believe this twist on vaccination could prove [... want %more?] → https://old.reddit.com/r/CoronaVirus_2019_nCoV/comments/w2qy4f/nasal_vaccines_whats_the_latest_research_on_nasal/13:59
BrainstormUpdates for Poland: +3248 cases, +5 deaths since a day ago — Kazakhstan: +3000 cases since 4 hours ago — Vietnam: +1097 cases since 23 hours ago14:02
BrainstormNew from Novavax: (news): Novavax Announces Expanded Agreement with SK bioscience to Manufacture COVID-19 Vaccine Containing Omicron Variant and Manufacture [... want %more?] → https://ir.novavax.com/2022-07-19-Novavax-Announces-Expanded-Agreement-with-SK-bioscience-to-Manufacture-COVID-19-Vaccine-Containing-Omicron-Variant-and-Manufacture-the-Novavax-COVID-19-Vaccine-in-Prefilled-Syringes14:36
BrainstormNew from Reddit (test): nCoV: If the new COVID variant is resistant to immunity, are the vaccines and boosters worth it? | 19JUL22 → https://old.reddit.com/r/nCoV/comments/w2rrv7/if_the_new_covid_variant_is_resistant_to_immunity/14:46
BrainstormNew from COVID on Twitter: Tulio de Oliveira (@Tuliodna): It is amazing the world ignoring this! Today I got a visit from German parliamentarians and one in the health cluster highlighted to me that over 1,000 cases in Berlin alone. Time to wake up and control an epidemic in initial stages or wait and see and risk [... want %more?] → https://twitter.com/Tuliodna/status/154937548080097280114:56
BrainstormUpdates for Indonesia: +5085 cases, +6 deaths, +127033 tests since a day ago — New Caledonia: +1403 cases since 7 days ago15:04
BrainstormNew from Contagion Live: Report: COVID-19 Had Dramatic Effect on Life Expectancies of Poor and Minorities: Though all racial and ethnic groups saw declines in life expectancy, the impact was greater among members of minority groups. → https://www.contagionlive.com/view/report-covid-19-had-dramatic-effect-on-life-expectancies-of-poor-and-minorities15:05
BrainstormNew from COVID on Twitter: Prof. Akiko Iwasaki (@VirusesImmunity): Here is a piece I wrote with Dr. Albert Ko on why we need booster doses to maintain our immune responses against SARS-CoV-2. Help educate your immune system by being up to date with your booster doses to prevent severe COVID. @YaleCII @YaleSPH [... want %more?] → https://twitter.com/VirusesImmunity/status/154938542789062656115:34
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): Muted warnings, a dearth of data"Most Americans are meeting a new Covid wave with a collective shrug, shunning masks, joining crowds indoors and moving on from the endless barrage of virus warnings of months past"nytimes.com/live/2022/07/1… @juliebosman [... want %more?] → https://twitter.com/EricTopol/status/154938971937253376115:53
BrainstormUpdates for Liechtenstein: +90 cases since 4 days ago — France: +1267 cases since 16 hours ago16:00
BrainstormNew from COVID on Twitter: Tom Wenseleers (@TWenseleers): All of this is not the end of the world, and I agree that real-life severity will likely keep on going down due to higher population immunity. But BA.2.75 does remain the most likely candidate to cause an infection wave in autumn. → https://twitter.com/TWenseleers/status/154939303834208256516:02
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): The incessant rise to the most transmissible and immune evasive variant yet, BA.5, with more to come, that is disregarded erictopol.substack.com/p/the-pandemic… → https://twitter.com/EricTopol/status/154939437719323033616:12
BrainstormNew from COVID on Twitter: Tom Wenseleers (@TWenseleers): I should also say that @WHO does already include BA.2.75 as a variant of concern alongside all other Omicron sublineages... So in that sense, the very question "should BA.2.75" be upgraded to a VOC is technically speaking moot. pic.twitter.com/3yioIeUbn4 → https://twitter.com/TWenseleers/status/154939844945131110816:22
BrainstormNew from COVID on Twitter: Tulio de Oliveira (@Tuliodna): @TWenseleers My conclusion, in hindsight, that the nomenclature got right as BA.2, BA.4 & BA.5 were easy to track due to simple names. The other 2 'emergent Omicron lineages' B.2.12.1 & BA.2.75 did not take over. But maybe just luck with naming and it is not [... want %more?] → https://twitter.com/Tuliodna/status/154940302897702912216:41
BrainstormNew from COVID on Twitter: Marc Veldhoen (@Marc_Veld): Doubting mainstream medicine, COVID patients find dangerous advice and pills onlineWhat happens if you are influenced by those who dismiss facts and play politics with health.npr.org/sections/healt… → https://twitter.com/Marc_Veld/status/154940555477424537616:51
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): BA.2.75 is a scariant. It is not spreading anywhere besides a couple of provinces in India without BA.5 to compete with. There will be other new variants to be concerned about but it doesn't look like this is one of them. twitter.com/Mike_Honey_/st… → https://twitter.com/EricTopol/status/154940719215094989217:00
BrainstormUpdates for Singapore: +13794 cases since 19 hours ago — Senegal: +63 cases, +1653 tests since a day ago17:03
BrainstormNew from COVID on Twitter: Tom Wenseleers (@TWenseleers): @Tuliodna @tomtom_m @rid1tweets Yes indeed, hence an excess death in the week of July 3d 2022 of 11893-10912=981. That's the excess death figures I used - I just calculated the cumulative total excess deaths per variant wave over all weeks. BA.1 and BA.4/5 [... want %more?] → https://twitter.com/TWenseleers/status/154940970501300224017:10
BrainstormNew from COVID on Twitter: Tom Wenseleers (@TWenseleers): @firefoxx66 @PeacockFlu @DrCJ_Houldcroft @BillHanage @jbloom_lab @Turelli_EPFL Some analyses of growth rate advantage of BA.2.75 also in thread below, which may be useful... twitter.com/TWenseleers/st… → https://twitter.com/TWenseleers/status/154941238446012006617:19
BrainstormNew from COVID on Twitter: Michael Lin, MD PhD   (@michaelzlin): Seems to have been a bad game of telephone based on a WHO slide that was made for both replication-competent and -incompetent Ad vaccines pic.twitter.com/vMk4wBbz4v → https://twitter.com/michaelzlin/status/154941468989287629017:29
BrainstormNew from COVID on Twitter: Michael Lin, MD PhD   (@michaelzlin): This graphic I made reflects our current understanding of vaccines pic.twitter.com/KctAsgo45Q → https://twitter.com/michaelzlin/status/154941677424396288317:39
BrainstormNew from COVID on Twitter: Steve Miller (@SteveMillerOC): Simultaneously declaring: we must incur every cost available to reduce infection, and the danger of severe disease from infection has been solved by vaccination.Completely irrational. twitter.com/lacuscmedcente… → https://twitter.com/SteveMillerOC/status/154942023312271360117:48
BrainstormNew from COVID on Twitter: Prof. Shane Crotty (@profshanecrotty): We provided the 2x Novavax immunized donor samples, which we extensively compared to mRNA and J&J vaccines for immune memory antibodies, CD4 T cells, CD8 T cells, and memory B cells in a recent paper  sciencedirect.com/science/articl… → https://twitter.com/profshanecrotty/status/154942036789413068917:58
BrainstormNew from COVID on Twitter: Josiah Grindrod is basically endemic (@JT_Grindrod): @Tuliodna @TWenseleers We had a 2.12.1 epidemic in the US, especially in the northeast.H/t @RajlabN pic.twitter.com/6LUiidrtD7 → https://twitter.com/JT_Grindrod/status/154942289032341094918:07
BrainstormUpdates for Greece: +367629 cases, +231 deaths since 9 days ago — Italy: +121103 cases, +176 deaths, +519284 tests since 23 hours ago — Serbia: +3912 cases, +5 deaths, +13677 tests since a day ago — Spain: +40589 cases, +279 deaths since 3 days ago19:01
BrainstormNew from StatNews: Breaking News: As overdose deaths exploded during the pandemic, racial disparities widened, CDC report shows → https://www.statnews.com/2022/07/19/overdose-deaths-exploded-2020-pandemic-racial-disparities-widened/19:04
BrainstormNew from COVID on Twitter: Tulio de Oliveira (@Tuliodna): We would like to wish our double vaccinated Health Minister Phaahla’s a quick recovery and remind that Covid is not over. news24.com/citypress/news… → https://twitter.com/Tuliodna/status/154944373812413235219:23
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): Interesting to see the comparison of neutralizing antibodies vs. BA.5 induced by 3 mRNA vaccines vs 2 Novavax shots and an mRNA booster pic.twitter.com/iSam76noTH → https://twitter.com/EricTopol/status/154944566732768460919:32
BrainstormNew from BioNTech: Pfizer and BioNTech Complete Submission to European Medicines Agency for Omicron BA.1 Adapted Bivalent Vaccine Candidate: NEW YORK and MAINZ, GERMANY, July 19, 2022 — Pfizer Inc. (NYSE: PFE) and BioNTech SE (Nasdaq: BNTX) today [... want %more?] → https://investors.biontech.de/news-releases/news-release-details/pfizer-and-biontech-complete-submission-european-medicines19:51
BrainstormNew from COVID on Twitter: Dr Emma Hodcroft (@firefoxx66): It feels like so many people have had COVID recently - that's 13% & a summer wave. Yet it's been felt in staffing & in hospitals (both in patients & staff).I do think it's worth considering, what level of disruption is worth trying to prevent come autumn? [... want %more?] → https://twitter.com/firefoxx66/status/154945245486931148920:01
BrainstormUpdates for Sri Lanka: +62 cases, +3 deaths since a day ago20:09
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): For people age 50+, a 2nd booster has been shown in multiple reports to save lives and/or reduce severe diseaseIn the US, % with 2nd shot by ageage 50-64: 9%age 65+: 23%cdc.gov/vaccines/acip/… pic.twitter.com/828TrnhXTf → https://twitter.com/EricTopol/status/154945385008763289620:10
BrainstormNew from CIDRAP: News Scan for Jul 19, 2022: COVID-19 death and blood viscosity More avian flu in US, Europe Global flu plateaus → https://www.cidrap.umn.edu/news-perspective/2022/07/news-scan-jul-19-202220:29
BrainstormNew from WebMD: Do I Have Long COVID? Here’s How to Tell: More than 200 symptoms can be linked to long COVID. But perhaps the one that stands out the most is constant fatigue that interferes with daily life. → https://www.webmd.com/lung/news/20220719/do-i-have-long-covid20:39
BrainstormNew from StatNews: STAT+: Pharma and patient advocates offer competing visions for achieving vaccine equity during pandemics: Amid criticism over its approach to Covid-19, the pharmaceutical industry has issued a new “declaration” to work closer with intra-governmental groups in [... want %more?] → https://www.statnews.com/pharmalot/2022/07/19/covid19-pandemic-vaccine-equity-patents/21:45
BrainstormUpdates for France: +135455 cases, +144 deaths since 22 hours ago — UAE: +1378 cases, +2 deaths since a day ago — Spain: +1094 cases since 3 hours ago — Canada: +1050 cases since 18 hours ago22:02
BrainstormNew from University of Washington: Novavax COVID-19 vaccine, recently cleared by U.S. regulators, was tested at UW: Screen Shot 2022-07-19 at 12.56.02 PM.png Close Scientists design updates to the Novavax’s COVID-19 shots in the company’s research [... want %more?] → https://globalhealth.washington.edu/news/2022/07/19/novavax-covid-19-vaccine-recently-cleared-us-regulators-was-tested-uw22:04
BrainstormNew from CIDRAP: Survey: COVID + childcare woes = burnout in health workers: Mary Van Beusekom | News Writer | CIDRAP News Jul 19, 2022 Stress from childcare issues amid the pandemic was tied to an 80% higher chance of burnout. → https://www.cidrap.umn.edu/news-perspective/2022/07/survey-covid-childcare-woes-burnout-health-workers22:14
BrainstormNew from Novavax: (news): U.S. CDC Advisory Committee Unanimously Recommends Novavax COVID-19 Vaccine, Adjuvanted as a Primary Series for Individuals Aged 18 and Older → https://ir.novavax.com/2022-07-19-U-S-CDC-Advisory-Committee-Unanimously-Recommends-Novavax-COVID-19-Vaccine,-Adjuvanted-as-a-Primary-Series-for-Individuals-Aged-18-and-Older22:33
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): If you were trying to prevent Covid infections, spread, #LongCovid, hospitalizations, & deaths, would you?—say 2 shots is "fully vaccinated"—say 5 days isolation is OK, no rapid test—be the 67th lowest country in the world for % boosters—give muted [... want %more?] → https://twitter.com/EricTopol/status/154949356701748019222:42
BrainstormNew from CIDRAP: CDC panel recommends Novavax vaccine as BA.5 gains more ground: Lisa Schnirring | News Editor | CIDRAP News Jul 19, 2022 BA.4 and BA.5 Omicron subvariants now make up about 90% of sequenced samples. → https://www.cidrap.umn.edu/news-perspective/2022/07/cdc-panel-recommends-novavax-vaccine-ba5-gains-more-ground23:22
BrainstormNew from COVID on Twitter: Prof. Shane Crotty (@profshanecrotty): @EricTopol With mRNA trending higher. So my assessment is peak titers are probably similar, when matched for age & time post immunization (which was controlled for in the clinical trial). Comparing antibody durability post-boost is not well [... want %more?] → https://twitter.com/profshanecrotty/status/154950553097190195223:32

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