libera/##covid-19/ Wednesday, 2022-07-27

BrainstormUpdates for Spain: +27924 cases, +203 deaths since 4 days ago — Barbados: +470 cases since 22 hours ago00:06
BrainstormNew from COVID on Twitter: Tom Inglesby, MD (@T_Inglesby): Just attended useful White House briefing on Fed US Monkeypox response- 5 goals of strategy: 1) rapidly scale up vaccination 2) expand testing 3) increase access to treatment (w/ reduced paperwork) 4) drive research to address key science gaps 5) community [... want %more?] → https://twitter.com/T_Inglesby/status/155204896752506061600:11
BrainstormNew from University of Washington: COVID-19 reinfections on the rise as officials call for a new booster: Screen Shot 2022-07-26 at 3.32.30 PM.png Close Photo by Go Nakamura/Getty Images View image caption The Washington State Department of Health has released a new [... want %more?] → https://globalhealth.washington.edu/news/2022/07/26/covid-19-reinfections-rise-officials-call-new-booster00:39
BrainstormUpdates for Sri Lanka: +119 cases, +5 deaths since a day ago — Algeria: +94 cases since 23 hours ago01:02
BrainstormNew from COVID on Twitter: Michael Lin, MD PhD   (@michaelzlin): Since Omicron is ruining everyone's summer trips, curious how long you are contagious for?Viral loads drop each day by 0.7 logs = 10⁰'⁷ = 5x from time of first measurement, which in turn is 2d after positive PCRnejm.org/doi/full/10.10… [... want %more?] → https://twitter.com/michaelzlin/status/155206907006475878601:16
BrainstormNew from COVID on Twitter: Michael Lin, MD PhD   (@michaelzlin): PCR positivity seems to lag first symptoms by 2 days on average, because if you graph the same time to culture negativity from PCR or symptoms whichever is earlier, you get an extra two days. So the median is likely 7 days from first symptoms. [... want %more?] → https://twitter.com/michaelzlin/status/155207095070685184001:26
BrainstormNew from COVID on Twitter: Michael Lin, MD PhD   (@michaelzlin): This means that the observation that vaccines and boosters helps prevent severe late COVID19 can't be explained by faster clearance of the virus in the early phase, at least not in the nose. → https://twitter.com/michaelzlin/status/155207317034508697701:35
BrainstormNew from COVID on Twitter: Michael Lin, MD PhD   (@michaelzlin): We saw Paxlovid clearing faster and preventing late disease, so the general assumption was less virus the better. But this appears not to be the case with vaccines, at least for virus in the nose.Could be Pax and vax clear virus from lungs faster [... want %more?] → https://twitter.com/michaelzlin/status/155207317118806016001:44
BrainstormNew from COVID on Twitter: Michael Lin, MD PhD   (@michaelzlin): This adds to earlier studies showing no vax effect on viral levels in the first week. This is beating a dead horse, but shows that Delta already refuted the idea that "vaccinated don't transmit", one of the minimizations I was trying to correct in [... want %more?] → https://twitter.com/michaelzlin/status/155208106373157273602:03
-Bridgestorm- ⭕ Lindol! Earthquake! 6.1 Mb tremor, registered by GEOFON,alomax, with 119 reports, 28 early, occurred 14 minutes ago (00:43:30 UTC), during daytime, Bantay, Philippines (17.45, 120.8) ± 67 km, ↓28 km likely felt 500 km away (in Tuguegarao…) by 1.8 million people (Twitter)02:57
BrainstormUpdates for Panama: +6390 cases, +17 deaths since 7 days ago — Slovakia: +1848 cases since 23 hours ago — Trinidad and Tobago: +359 cases, +1 deaths, +1515 tests since a day ago — Canada: +7385 cases since 23 hours ago03:00
-Bridgestorm- ⭕ Lindol! Earthquake! 7.2 Mb tremor, registered by scevent, occurred 27 minutes ago (00:43:24 UTC), during daytime, Lagangilang, Philippines (17.6, 120.81), ↓5 km likely felt 580 km away (in Bangued, Lagangilang, Bucay, La Paz, Tayum, Dolores…) by 1.7 million people (service.geonet.org.nz)03:11
BrainstormNew from Reddit (test): Covid2019: Stanford Researchers Looking Into Nasal Spray to Fight COVID-19 Spread → https://old.reddit.com/r/Covid2019/comments/w91pp6/stanford_researchers_looking_into_nasal_spray_to/03:58
BrainstormNew from COVID on Twitter: Michael Lin, MD PhD   (@michaelzlin): Should clarify that I meant the metric of PCR+ lags the metric of symptom onset by 2d in this study. People were not PCRing daily (very very few studies do that), so likely only sought PCR testing after 2d of symptoms on average.Actual meaning lost [... want %more?] → https://twitter.com/michaelzlin/status/155211192629278310404:07
BrainstormUpdates for Germany: +121780 cases, +181 deaths since 23 hours ago — Eritrea: +22 cases since a day ago06:01
BrainstormUpdates for Tokyo, Japan: +31593 cases, +5 deaths since 23 hours ago — Osaka, Japan: +25762 cases, +12 deaths since 23 hours ago — Aichi, Japan: +15315 cases, +5 deaths since 23 hours ago — Fukuoka, Japan: +11948 cases, +9 deaths since 23 hours ago07:59
BrainstormNew from MedicineNet: (news): Is the War Against COVID Variants Won in the Nose? → http://www.medicinenet.com/script/main/art.asp08:54
BrainstormNew from r/Coronavirus: Daily Discussion Thread | July 27, 2022: Please refer to our Wiki for more information on COVID-19 and our sub. You can find answers to frequently asked questions in our FAQ , where there is valuable information such as our: → https://old.reddit.com/r/Coronavirus/comments/w97r24/daily_discussion_thread_july_27_2022/09:04
BrainstormUpdates for Laos: +86 cases since 23 hours ago10:04
BrainstormNew from COVID on Twitter: Tom Wenseleers (@TWenseleers): @Tuliodna @MarionKoopmans Agree travel bans were counterproductive, but to be fair: a lot of countries worldwide imposed travel bans to the UK following the discovery of the Alpha variant. Was in S Africa low vaccination coverage also not result of vaccine [... want %more?] → https://twitter.com/TWenseleers/status/155220218084892672010:10
BrainstormUpdates for Hungary: +14402 cases, +54 deaths since 5 days ago — Himachal Pradesh, India: +986 cases, +1 deaths since a day ago — Jammu and Kashmir, India: +697 cases since a day ago — Uttarakhand, India: +282 cases since a day ago11:06
BrainstormNew from PubMed: Association Between Maintenance Immunosuppressive Regimens and COVID-19 Mortality in Kidney Transplant Recipients: CONCLUSIONS: Corticosteroid-free regimens were associated with a lower risk of death in KT recipients with COVID-19. Long-term exposure to corticosteroids impairs immune functions and may predispose [... want %more?] → https://pubmed.ncbi.nlm.nih.gov/35883236/11:06
BrainstormUpdates for Russia: +9027 cases, +36 deaths since 23 hours ago12:09
BrainstormNew from Reddit (test): 27/07/22 - ZOE COVID-19 Study Update: 4,116,340 people are currently predicted to have symptomatic COVID-19 in the UK, down by 105,478. Yesterday was 4,221,818 (-2%) and last Wednesday was 4,635,430 (-11%). → https://old.reddit.com/r/CoronavirusUK/comments/w9amzy/270722_zoe_covid19_study_update/12:41
BrainstormNew from BioNTech: Pfizer and BioNTech Advance COVID-19 Vaccine Strategy With Study Start of Next-Generation Vaccine Candidate Based on Enhanced Spike Protein Design: NEW YORK and MAINZ, Germany, July 27, 2022 — Pfizer Inc. (NYSE: PFE) and BioNTech [... want %more?] → https://investors.biontech.de/news-releases/news-release-details/pfizer-and-biontech-advance-covid-19-vaccine-strategy-study12:51
BrainstormNew from COVID on Twitter: Marc Veldhoen (@Marc_Veld): Well, no that was not an answer. But we hold hope.How does BCR en TCR rearrangement work? How do affinity maturation and SHM work? How does a vaccine work? twitter.com/BillHicks1984/… → https://twitter.com/Marc_Veld/status/155225612898101657913:38
BrainstormNew from COVID on Twitter: Marc Veldhoen (@Marc_Veld): Do you think Bil does not know about viral selection and variants or antibody waning? It seems not, but he does know more than the whole of the CDC. pic.twitter.com/ZmcLQgS83X → https://twitter.com/Marc_Veld/status/155225885574418432013:48
BrainstormNew from r/COVID19: COVID19: Pharmacometric assessment of the in vivo antiviral activity of ivermectin in early symptomatic COVID-19 → https://old.reddit.com/r/COVID19/comments/w9csjj/pharmacometric_assessment_of_the_in_vivo/13:57
BrainstormNew from Science-Based Medicine: New Studies on the Origin of COVID-19: New evidence strongly supports the conclusion that SARS-CoV-2 emerged from the wet markets of Wuhan, killing the lab-leak hypothesis. The post  first appeared on Science-Based Medicine . → https://sciencebasedmedicine.org/new-studies-on-the-origin-of-covid-19/14:07
Alex1138[m]oh, interesting14:08
undefined_bobyeah  I read that already. sounds like they got there something14:09
Alex1138[m]without reviewing the medical literature i guess i always intuitively felt it would be not from a lab (though that was a possibility)14:14
Alex1138[m]also because i think the lab leak hypothesis makes more difficult proposals14:19
BrainstormNew from Reddit (test): CoronaVirus_2019_nCoV: How COVID-19 affects the brain microvasculature → https://old.reddit.com/r/CoronaVirus_2019_nCoV/comments/w9dpt0/how_covid19_affects_the_brain_microvasculature/14:45
BrainstormNew from COVID on Twitter: Dr Emma Hodcroft (@firefoxx66): As someone who hasn't had COVID-19 (N-antibody absence confirmed), I agree - it's critical we have accurate messaging on this. Yes, risks are lower. But no, not everyone's had it (or recently or the same variant) - & our plans shouldn't assume everyone has. [... want %more?] → https://twitter.com/firefoxx66/status/155227660356417945615:05
BrainstormNew from Reddit (test): nCoV: How the omicron subvariant BA.5 became a master of disguise – and what it means for the current COVID-19 surge | 26JUL22 → https://old.reddit.com/r/nCoV/comments/w9e2us/how_the_omicron_subvariant_ba5_became_a_master_of/15:14
BrainstormNew from BMJ Open: Interaction effect between overweight/obesity and alcohol consumption on hypertension risk in China: a longitudinal study: Objective To explore the interaction effect between overweight/obesity and alcohol consumption on hypertension risk. Design A longitudinal study of the independent and combined [... want %more?] → http://bmjopen.bmj.com/cgi/content/short/12/7/e06126115:43
BrainstormNew from COVID on Twitter: Marc Veldhoen (@Marc_Veld): Okay, Not knowing the difference between SARS-CoV-2 and COVID-19.  Not sure about the expertise. of Bill. pic.twitter.com/SvCxkO1upV → https://twitter.com/Marc_Veld/status/155228847526481920315:53
BrainstormNew from EMA: News and press releases: EMA reviewing data on sabizabulin for COVID-19 , , 27/07/2022: EMA’s Emergency Task Force (ETF) has started a review of data on the use of sabizabulin for treating COVID-19.The review will look at all available... → https://www.ema.europa.eu/en/news/ema-reviewing-data-sabizabulin-covid-1916:02
BrainstormNew from r/COVID19: COVID19: Duration of viable virus shedding in SARS-CoV-2 omicron variant infection → https://old.reddit.com/r/COVID19/comments/w9g36m/duration_of_viable_virus_shedding_in_sarscov2/16:31
BrainstormNew from COVID on Twitter: Dr Emma Hodcroft (@firefoxx66): As before, I've created a file for 22D / BA.2.75 mapping all defining mutations (relative to ancestral), including nuc->AA. This is available on CoV github! Huge    to all who helped check it! (Esp @DoktorYak & Anna N!) (Further feedback [... want %more?] → https://twitter.com/firefoxx66/status/155230671482901300017:00
BrainstormNew from StatNews: Can we really get better Covid vaccines? There are big hurdles, but some hope: At a White House summit on next-generation Covid vaccines, there was tremendous optimism — and glimmers of a tractable path to better products. → https://www.statnews.com/2022/07/27/can-we-really-get-better-covid-vaccines-there-are-big-hurdles-but-some-hope/17:10
BrainstormNew from ClinicalTrials.gov: (news): Study to Investigate the Mass Balance and Biotransformation of SIM0417 in Healthy Adult Chinese Male Participants → https://clinicaltrials.gov/ct2/show/NCT0547583417:30
BrainstormUpdates for Serbia: +6102 cases, +10 deaths, +16311 tests since 22 hours ago18:10
BrainstormNew from ClinicalTrials.gov: (news): Emergency Surgery During Covid Compared to Emergency Surgery During Pre-covid Period → https://clinicaltrials.gov/ct2/show/NCT0547631518:18
BrainstormNew from COVID on Twitter: Tom Wenseleers (@TWenseleers): So the final estimate (right panel) for Omicron seems to be that it caused a ca. 50% drop in VE in terms of transmission due to immune escape and had only slightly higher R0 than Delta. Technically, we'd still need generation time too. Close to my gut [... want %more?] → https://twitter.com/TWenseleers/status/155232885425304780918:27
BrainstormUpdates for Italy: +64400 cases, +207 deaths since 22 hours ago19:00
BrainstormNew from COVID on Twitter: Michael Lin, MD PhD   (@michaelzlin): BTW a BA.5 booster would have demonstrated innovative thinking and an ability to look around corners but why is it not surprising that this didn't happen.The only government technical initiative taken in this epidemic was OWS and Pfizer didn't even [... want %more?] → https://twitter.com/michaelzlin/status/155233811059534233719:05
BrainstormNew from WebMD: No Long COVID Drugs Yet, But Other Treatments Available: There's no specific drug to treat long COVID yet. But as long COVID clinics have sprout up across the country, there are more and more options for patients who deal with lingering, but life-altering symptoms. → https://www.webmd.com/lung/news/20220727/no-long-covid-drugs-yet-other-treatments19:15
BrainstormUpdates for Japan: +209600 cases, +129 deaths since 23 hours ago20:02
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): Yet another pan-coronavirus candidate reported today (vs S2 of the spike) adds to the list >30science.org/doi/10.1126/sc… by @TheCrick @KevinWNg @nikifaulknerAnd good @WIRED review of their statuswired.com/story/these-va… by @ChenMaggieSY pic.twitter.com/j3rzrxcnKo → https://twitter.com/EricTopol/status/155235536882246041620:13
BrainstormNew from COVID on Twitter: Balazs Lab (@BalazsLab): We think these findings mean that at low concentrations of antibodies, these innate functions can really make the difference in whether or not you prevent HIV transmission.  Maybe we'll find a way to take advantage of this observation to make even better antibodies [... want %more?] → https://twitter.com/BalazsLab/status/155235696335010201620:22
BrainstormNew from COVID on Twitter: Jeffrey Barrett (@jcbarret): The first half (Broad St pump) of the @MichaelWorobey et al paper clearly shows Huanan was the epicenter of the outbreak that seeded the pandemic:       BUT you could argue that doesn't prove there wasn't an upstream lab leak and cryptic spread to Huanan:    [... want %more?] → https://twitter.com/jcbarret/status/155236002668938855020:32
BrainstormNew from COVID on Twitter: Prof. Akiko Iwasaki (@VirusesImmunity): One of the highlights of yesterday’s @WHCOVIDResponse summit on future of COVID vaccines is getting to meet new people. What an honor to share the panel with Dr. Michelle Smith from @ADHPIO. Hope to collaborate with her in communicating the [... want %more?] → https://twitter.com/VirusesImmunity/status/155236214659139174520:42
BrainstormNew from COVID on Twitter: Gunhild Alvik Nyborg (@GANyborg): Inst for Fiscal Studies UK finds 110,000 missing from work as result of #LongCovid at a cost of £1.5 billion/year in lost earningsWho thought the economy would profit from letting everybody get sick repeatedly?Time our insts of public health get back at [... want %more?] → https://twitter.com/GANyborg/status/155236555494993510420:51
BrainstormNew from COVID on Twitter: Tulio de Oliveira (@Tuliodna): In spite of African scientists & public health agencies highlighting the danger of Monkeypox for years. Today, AfricaCDC criticised that tools to address the outbreak, including diagnostics, treatments, and vaccines, have not been made available to Africa. Deja [... want %more?] → https://twitter.com/Tuliodna/status/155236731877220352321:01
-Bridgestorm- 🌎 Temblor! Sismo! Earthquake! 6.0 Mb tremor, registered by EMSC,KOERI,alomax, with 40 reports, 4 early, occurred 11 minutes ago (18:58:56 UTC), during daytime, Calama, Chile (-22.24, -68.83) ± 28 km likely felt 380 km away (www.seismicportal.eu)21:10
-Bridgestorm- ⭕ Sismo! Earthquake! 6.1 Mww tremor, registered by HKOEARTHQUAKE5E,US, occurred 18 minutes ago (18:58:57 UTC), during daytime, Calama, Chile (-22.24, -68.6) ± 17 km, ↓73 km likely felt 300 km away (in Calama…) by 138700 people (Twitter)21:17
-Bridgestorm- ⭕ Sismo! Earthquake! 6.2 Mww tremor, registered by EMSC,HKOEARTHQUAKE5E,US, occurred 19 minutes ago (18:58:57 UTC), during daytime, Calama, Chile (-22.21, -68.48) ± 3 km, ↓53 km likely felt 310 km away (in Calama…) by 138700 people (www.seismicportal.eu)21:18
BrainstormNew from WebMD: More Evidence That COVID-19 Started in Wuhan Marketplace: The virus driving the COVID-19 pandemic started as two slightly different strains, jumping to humans a few weeks apart at the end of 2019, research shows. → https://www.webmd.com/lung/news/20220727/more-evidence-covid-started-in-marketeplace21:29
BrainstormNew from r/COVID19: COVID19: Risk factors associated with SARS-CoV-2 infection in a multiethnic cohort of United Kingdom healthcare workers (UK-REACH): A cross-sectional analysis → https://old.reddit.com/r/COVID19/comments/w9nkjm/risk_factors_associated_with_sarscov2_infection/21:48
BrainstormUpdates for Georgia: +10953 cases since 5 days ago — Oman: +2735 cases since 8 days ago — France: +51207 cases, +90 deaths since 23 hours ago22:00
BrainstormNew from Contagion Live: Full COVID-19 Vaccination Cuts Reinfection Risk in Half: Prior infection is not enough: COVID-19 vaccination reduces the risk of reinfection by 50%. → https://www.contagionlive.com/view/full-covid-19-vaccination-cuts-reinfection-risk-in-half22:07
BrainstormNew from CIDRAP: Persistent brain fog, hair loss highlighted in long-COVID studies: Mary Van Beusekom | News Writer | CIDRAP News Jul 27, 2022 Of hospitalized COVID patients, 53% still had brain fog 13 months later. → https://www.cidrap.umn.edu/news-perspective/2022/07/persistent-brain-fog-hair-loss-highlighted-long-covid-studies22:26
BrainstormNew from Medical Xpress: What bats can teach us about stopping the next pandemic: Why are bats often linked to incubating coronaviruses such as those behind COVID-19, SARS and other highly contagious respiratory diseases? → https://medicalxpress.com/news/2022-07-pandemic.html22:36
BrainstormNew from COVID19 Vaccine Tracker: valerie: Altimmune Inc: AdCOVID → https://covid19.trackvaccines.org/vaccines/75/22:46
BrainstormNew from CIDRAP: COVID hot spots shift; studies add evidence for Wuhan market origin: Lisa Schnirring | News Editor | CIDRAP News Jul 27, 2022 Studies suggest the market didn't just amplify virus spread, it was the early epicenter and site of SARS-CoV-2 emergence. → https://www.cidrap.umn.edu/news-perspective/2022/07/covid-hot-spots-shift-studies-add-evidence-wuhan-market-origin22:55
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): Tens of millions of vaccine doses in the US are about to expire in the US and will be wasted.2nd booster doses should be made available to all age <50 who want added protection now → https://twitter.com/EricTopol/status/155239842995064422523:05
BrainstormUpdates for Canada: +1789 cases since 23 hours ago23:09

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