libera/##covid-19/ Friday, 2022-07-29

BrainstormUpdates for India: +21114 cases since 23 hours ago — Algeria: +98 cases since 23 hours ago — Mali: +4 cases, +2 deaths, +815 tests since 2 days ago00:09
BrainstormNew from Ars Technica: Science: Gulf Coast tests confirm deadly tropical soil bacterium now endemic to US → https://arstechnica.com/?p=187010900:30
BrainstormNew from r/COVID19: COVID19: A mixed methods study on effectiveness and appropriateness of face shield use as COVID-19 PPE in middle income countries → https://old.reddit.com/r/COVID19/comments/wan69z/a_mixed_methods_study_on_effectiveness_and/00:40
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): In a Portugal, a country with a highly vaccinated population (>98% of a nationwide study population ≥ 2 shots), prior infection with Omicron BA.1/BA.2 protected well vs BA.5 breakthrough infections medrxiv.org/cgi/content/sh… pic.twitter.com/pREcZuxx7r → https://twitter.com/EricTopol/status/155279216795270758501:08
BrainstormUpdates for Micronesia: +1454 cases, +3 deaths since 2 days ago — Canada: +9998 cases since 23 hours ago02:01
LjLde-facto, https://www.science.org/content/article/bad-news-paxlovid-coronavirus-can-find-multiple-ways-evade-covid-19-drug02:23
BrainstormNew from ##covid-19 Zotero group: Bad news for Paxlovid? Coronavirus can find multiple ways to evade COVID-19 drug: Type Web Page URL https://www.science.org/content/article/bad-news-paxlovid-coronavirus-can-find-multiple-ways-evade-covid-19-drug Accessed 2022-07-29 00:34:06 Language en Abstract Lab studies identify [... want %more?] → https://www.zotero.org/groups/covid_links/items/D7CERXU202:43
BrainstormUpdates for Ghana: +792 cases, +1 deaths, +9328 tests since 15 days ago — Jamaica: +180 cases, +1 deaths, +936 tests since 2 days ago — Syria: +55 cases since a day ago03:04
BrainstormNew from Reddit (test): Covid2019: [PDF] A central role for amyloid fibrin microclots in long COVID/PASC: origins and therapeutic implications | Semantic Scholar → https://old.reddit.com/r/Covid2019/comments/waqvyg/pdf_a_central_role_for_amyloid_fibrin_microclots/03:11
BrainstormNew from Reddit (test): nCoV: Are Amyloid Fibrin Microclots Central to Long COVID? - Hematology Advisor → https://old.reddit.com/r/nCoV/comments/waqygp/are_amyloid_fibrin_microclots_central_to_long/04:17
BrainstormNew from NPR Science: Summer boosters for people under 50 shelved in favor of updated boosters in the fall: The Biden administration is scrapping plans to offer COVID boosters for people under 50 this summer. Instead they will [... want %more?] → https://www.npr.org/sections/health-shots/2022/07/28/1114408611/summer-boosters-for-people-under-50-shelved-in-favor-of-updated-boosters-in-the-05:05
BrainstormUpdates for Germany: +84798 cases, +153 deaths since a day ago — Wallis and Futuna, France: +174 cases since a day ago06:10
BrainstormNew from COVID on Twitter: Tulio de Oliveira (@Tuliodna): We will miss you @amymaxmen but we will keep our radical plan to produce vaccines, diagnostics and therapeutics in Africa and work hard so science in LMICs can help the world to quickly identify pathogens and save lives. twitter.com/amymaxmen/stat… → https://twitter.com/Tuliodna/status/155287696837440307506:48
BrainstormUpdates for Tokyo, Japan: +40406 cases, +7 deaths since 23 hours ago — Ohio, United States: +29876 cases since 6 hours ago — Osaka, Japan: +24289 cases, +21 deaths since 23 hours ago — Bogota, Colombia: +16034 cases since 6 days ago08:09
BrainstormNew from Reddit (test): CoronaVirus_2019_nCoV: Naturally-infected, captive white-tailed deer in Texas have persistent anti-SARS-CoV-2 antibodies → https://old.reddit.com/r/CoronaVirus_2019_nCoV/comments/wax37u/naturallyinfected_captive_whitetailed_deer_in/08:23
BrainstormNew from Reddit (test): Covid2019: Persistence of SARS-CoV-2 neutralizing antibodies longer than 13 months in naturally-infected, captive white-tailed deer (Odocoileus virginianus), Texas | bioRxiv → https://old.reddit.com/r/Covid2019/comments/waxfs2/persistence_of_sarscov2_neutralizing_antibodies/08:41
BrainstormNew from Reddit (test): CoronaVirus_2019_nCoV: Symptoms Persist in Patients Two Years after COVID-19 infection: A Prospective Follow Up Study - Clinical Microbiology and Infection → https://old.reddit.com/r/CoronaVirus_2019_nCoV/comments/waxrey/symptoms_persist_in_patients_two_years_after/09:00
BrainstormNew from Science-Based Medicine: “Natural Immunity” Stans Forget Babies Will Always be Vulnerable to COVID: Children are still getting hospitalized with COVID, no matter how many times contrarian doctors mindlessly repeat the mantra "natural immunity".  Doctors who know where babies come from understand why this might be. The [... want %more?] → https://sciencebasedmedicine.org/obviously/09:09
BrainstormNew from Reddit (test): CoronaVirus_2019_nCoV: Pfizer and BioNTech Advance COVID-19 Vaccine Strategy With Study Start of Next-Generation Vaccine Candidate Based on Enhanced Spike Protein Design | BNT162b5, consists of RNAs encoding enhanced prefusion spike proteins [... want %more?] → https://old.reddit.com/r/CoronaVirus_2019_nCoV/comments/way22p/pfizer_and_biontech_advance_covid19_vaccine/09:18
BrainstormNew from StatNews: Drug companies could create new drugs to protect the Covid vulnerable. Why aren’t they?: Though Evusheld is useful against Omicron, few other prophylactic drugs for people with compromised immune systems are on the horizon. → https://www.statnews.com/2022/07/29/new-prophylactic-covid-drugs-for-immunocompromised-where-are-they/10:43
BrainstormNew from COVID on Twitter: (translated) Joel De Ceulaer (@jdceulaer): This week I had the opportunity to interview @TWenseleers, the biologist who became an international pandemic expert as a hobby. A conversation about covid, waves, vaccines, privacy rules and of course: monkeypox. demorgen.be/a-bce27e72 → https://twitter.com/jdceulaer/status/155294426788211097711:52
BrainstormUpdates for Russia: +11422 cases, +39 deaths since 23 hours ago11:59
BrainstormNew from EMA: Human medicine assessment reports: (news): Human medicines European public assessment report (EPAR): Regkirona, regdanvimab, COVID-19 virus infection, Date of authorisation: 12/11/2021, Revision: 4, Status: Authorised → https://www.ema.europa.eu/en/medicines/human/EPAR/regkirona12:21
BrainstormNew from COVID on Twitter: (translated) Tom Wenseleers (@TWenseleers): Interview in De Morgen by @jdceulaer. A look back at the Covid pandemic. About the annoyingly slow approval of modified Covid vaccines, privacy rules that made sharing medical data difficult and cost so many lives and monkeypox. demorgen.be/ts-bce27e72 → https://twitter.com/TWenseleers/status/155296854255901081612:50
BrainstormNew from COVID on Twitter: Marc Veldhoen (@Marc_Veld): Impaired ketogenesis ties metabolism to T cell dysfunction in COVID-19β-hydroxybutyrate is an alternative carbon source promoting T cell responses in pulmonary viral infections: dysregulation may contribute to COVID-19 ARDS.Great work from [... want %more?] → https://twitter.com/Marc_Veld/status/155298131185339596913:38
BrainstormNew from EMA: Human medicine assessment reports: (news): Human medicines European public assessment report (EPAR): Nuvaxovid, COVID-19 Vaccine (recombinant, adjuvanted), COVID-19 virus infection, Date of authorisation: 20/12/2021, Revision: 3, Status: Authorised → https://www.ema.europa.eu/en/medicines/human/EPAR/nuvaxovid13:57
BrainstormNew from Reddit (test): nCoV: DoD Awards $1.74 Billion Agreement to Moderna, Inc. to Secure Over 65 Million Doses of COVID-19 Vaccine for Fall Vaccinations | 29JUL22 → https://old.reddit.com/r/nCoV/comments/wb3uh4/dod_awards_174_billion_agreement_to_moderna_inc/14:45
BrainstormUpdates for Philippines: +4128 cases, +14 deaths, +27891 tests since a day ago15:00
BrainstormNew from Contagion Live: us: COVID-19 Vaccine Boosters: Benefits, Expansion of Eligibility, and Mixing and Matching of Vaccines → https://www.contagionlive.com/view/covid-19-vaccine-boosters-benefits-expansion-of-eligibility-and-mixing-and-matching-of-vaccines15:05
BrainstormNew from Reddit (test): nCoV: Studies reveal racial disparities in early US COVID vaccine rollout | 28JUL22 → https://old.reddit.com/r/nCoV/comments/wb4fx3/studies_reveal_racial_disparities_in_early_us/15:14
BrainstormNew from StatNews: Pharma: STAT+: Pharmalittle: Pharma wages ‘hail Mary’ campaign to sink reconciliation bill; Moderna inks $1.74 billion deal with U.S. for Omicron shot → https://www.statnews.com/pharmalot/2022/07/29/covid19-vaccine-moderna-medicare-hiv-bausch-cvs/15:33
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): I had the chance to discuss intrinsic protection from Covid with my friend @ASlavitt twitter.com/inthebubblepod… twitter.com/EricTopol/stat… → https://twitter.com/EricTopol/status/155301854966426419216:11
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): It's not at all benign, even in a well vaccinated population pic.twitter.com/qAz8Rxgd1A → https://twitter.com/EricTopol/status/155302093368147558516:21
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): I have many questions about the BA.5-specific booster in Sept plannytimes.com/2022/07/28/us/…1. How did it get accelerated from Oct/Nov?2. It took 7 mos for a BA.1 (unused), but 2 for BA.5?3. Why not offer millions of doses to be discarded now for HCW and [... want %more?] → https://twitter.com/EricTopol/status/155302667350258892816:40
BrainstormNew from r/COVID19: COVID19: Detection of SARS-CoV-2 in exhaled air using non-invasive embedded strips in masks → https://old.reddit.com/r/COVID19/comments/wb6mm6/detection_of_sarscov2_in_exhaled_air_using/17:09
BrainstormNew from ClinicalTrials.gov: (news): Allocating Resources for Cancer Care in Times of the Sars-CoV-2 Outbreak. Health Care Research → https://clinicaltrials.gov/ct2/show/NCT0547929217:19
BrainstormNew from ClinicalTrials.gov: (news): Immunogenicity and Safety of BBIBP-Cov Coadministered With PPV23 and IIV4 in Hemodialysis Population → https://clinicaltrials.gov/ct2/show/NCT0548043617:47
BrainstormUpdates for Micronesia: +795 cases since 15 hours ago18:00
BrainstormNew from ClinicalTrials.gov: Tobacco Use and Uptake of COVID-19 Vaccinations: Conditions :    COVID-19;   Smoking;   Tobacco Use;   Vaccination Refusal → https://clinicaltrials.gov/ct2/show/NCT0547938318:16
BrainstormNew from ScienceNews: I think I have long COVID. What does that mean?: The condition comes with varying levels of severity and symptoms, making it hard to diagnose and treat. → https://www.sciencenews.org/article/long-covid-definition-symptoms-treatment-coronavirus18:25
BrainstormUpdates for Italy: +54417 cases, +244 deaths, +281659 tests since 23 hours ago — Myanmar: +34 cases since 23 hours ago — Spain: +332 deaths since 2 days ago19:03
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): New @TheLancet The largest trial of baricitinib, a JAK-inhibitor drug repurposed via #AI data mining, reduced Covid mortality and the overall reduction consistent with 8 previous RCTs (~20%)thelancet.com/journals/lance… pic.twitter.com/GDFzcU26H6 → https://twitter.com/EricTopol/status/155306186287428812819:03
BrainstormNew from Contagion Live: Regular COVID-19 Screening in Schools Can Control Infections, Limit Closures: The model suggests screening unvaccinated students could reduce absences by 80% compared to reactively closing classes with infected students. → https://www.contagionlive.com/view/regular-covid-19-screening-in-schools-can-control-infections-limit-closures19:13
BrainstormNew from Politico: Lloyd’s to insure Black Sea grain shipments for up to $50M each: The UN, Turkey, Russia and Ukraine signed an agreement to reopen 3 Black Sea ports around Odesa last week. → https://www.politico.eu/article/lloyds-to-insure-black-sea-grain-ships-for-up-to-50m-each/19:33
BrainstormNew from COVID on Twitter: Marc Veldhoen (@Marc_Veld): Antibodies are a little easier:nature.com/articles/s4146… → https://twitter.com/Marc_Veld/status/155307215765518745619:42
BrainstormUpdates for Malaysia: +4860 cases, +10 deaths since a day ago20:05
BrainstormNew from COVID on Twitter: SPARK (@SPARK_Stanford): "if we’re lucky enough to get philanthropic support, then we can support some of the great host-targeting strategies that I know are being developed at Stanford by a variety of people."globalhealth.stanford.edu/covid-19/prepa… → https://twitter.com/SPARK_Stanford/status/155307499587352985620:11
BrainstormNew from ProPublica: New York Polio Case Now Connected to Traces of Virus Found in UK and Israel: by Robin Fields ProPublica is a nonprofit newsroom that investigates abuses of power. Sign up to receive our biggest stories as soon as they’re published. Public health officials’ international hunt [... want %more?] → https://www.propublica.org/article/polio-london-jerusalem-new-york#137983020:20
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): "Among 248,887... aged ≥50 years with homologous vaccination and a second booster dose, injection site and systemic reactions were less frequently reported after the second booster dose than the first booster dose" cdc.gov/mmwr/volumes/7… pic.twitter.com/aMUZKlvggP → https://twitter.com/EricTopol/status/155308332496855040020:30
BrainstormNew from CIDRAP: News Scan for Jul 29, 2022: Outcomes after COVID and stroke More WPV1 cases in Mozambique Unexplained hepatitis in kids → https://www.cidrap.umn.edu/news-perspective/2022/07/news-scan-jul-29-202220:39
BrainstormNew from FDA Press Releases: FDA Provides Update on Agency Response to Monkeypox Outbreak: Today, the FDA is providing an update on its multipronged response to monkeypox in the United States, including its efforts in the areas of diagnostics, vaccines and therapeutics. → http://www.fda.gov/news-events/press-announcements/fda-provides-update-agency-response-monkeypox-outbreak20:49
BrainstormUpdates for Serbia: +5951 cases, +12 deaths since a day ago — Canada: +3230 cases since 23 hours ago21:01
BrainstormNew from Contagion Live: Middle East, North Africa Face Emerging HIV Epidemics With Lagging Response: HIV epidemics are emerging among key populations in the Middle East and North Africa, and the region ranks lowest globally in response indicators, → https://www.contagionlive.com/view/middle-east-north-africa-face-emerging-hiv-epidemics-with-lagging-response21:07
BrainstormNew from COVID on Twitter: (translated) Marc Veldhoen (@Marc_Veld): J&J with 1x: definitely a booster is needed. 1-2 boosters or combinations with infection are probably enough. Then the same applies as above: a personal consideration with regard to infection and possible consequences for family, colleagues, work, [... want %more?] → https://twitter.com/Marc_Veld/status/155310133085138534421:36
BrainstormNew from COVID on Twitter: (translated) Marc Veldhoen (@Marc_Veld): A final advice: only get it > 3 months after a previous vaccination or infection.If you belong to a group that has a weaker immune system; 4th vaccine is highly recommended and necessary to protect you against disease as well! → https://twitter.com/Marc_Veld/status/155310133286057164921:45
BrainstormUpdates for France: +40268 cases, +82 deaths since 23 hours ago22:09
LjLthis Centaurus variant, what do we know?22:14
de-factodo you have a link?22:26
de-factodo you mean https://covariants.org/variants/22D.Omicron ?22:29
de-factohttps://cov-lineages.org/lineage.html?lineage=BA.2.7522:29
de-factolots of it in India it seems 70% or such22:30
de-factoerm 70% of its sequences come from India, not 70% of cases there are that mutant22:31
de-factothough seems to be increasing in Nepal, India, China22:34
de-factoBA.2.75 seems to take over BA.2 in Nepal, BA.2 in India (together with increasing BA.5), same for China22:37
de-factowhat do you know about it LjL ?22:37
LjLreally nothing, just that it was spotted in Italy now22:37
LjLyes BA.2.7522:37
LjLi guess the question is whether it beats BA.5 or not22:37
de-factoi think it also was in the news for USA iirc, but maybe was taken over by BA.5 there?22:38
de-factoin those graphs from covariants it looks like it makes a head to head race on BA.2 ground22:38
de-factobut those are not necessarily quantifying real prevalence of variants in terms of real incidence, just what happens to get sequenced and reach the databases22:39
BrainstormNew from COVID on Twitter: (translated) Marc Veldhoen (@Marc_Veld): Vaccinations protect for life. You don't get that, that's why you say such stupid things. You don't even know the difference between infection and disease; but hey you have a keyboard and an unsubstantiated opinion: and you have to share that [... want %more?] → https://twitter.com/Marc_Veld/status/155311773717354086622:44
de-factooh correction: i meant to say " i think BA.2.12.1 also was the news for USA iirc, but maybe was taken over by BA.5 there?" (so it was not BA.2.75 but BA.2.12.1)22:53
de-factoalso interesting, BA.2.75 seems to have no S-gene dropout anymore (e.g. those dels from Alpha) and aquired a mutation from Delta https://covariants.org/shared-mutations22:55
de-factoalso got some new ones (listed in the bottom)22:55
BrainstormUpdates for India: +20598 cases since 22 hours ago22:59
BrainstormNew from COVID on Twitter: (translated) Marc Veldhoen (@Marc_Veld): For example, vaccinations protect us safely against serious illness; they greatly reduce the risk of infection and transmission in the first months; after that, the risk of contamination will increase; but not those on serious illness! → https://twitter.com/Marc_Veld/status/155312417324914278423:14
Klindafirst Omicron wave was more deadly than omicron 5 or not?23:22
BrainstormNew from StatNews: U.S. polio case tied to viruses detected in U.K., Israel, suggesting silent spread: Genetic analysis of the virus responsible for the first case of polio in the United States in nearly a decade shows it is linked to vaccine-derived viruses [... want %more?] → https://www.statnews.com/2022/07/29/u-s-polio-case-tied-to-viruses-detected-in-u-k-israel-suggesting-silent-spread/23:55

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