libera/##covid-19/ Sunday, 2022-08-14

BrainstormNew from COVID on Twitter: Michael Lin, MD PhD   (@michaelzlin): And I wasn't sure this was positive. It was the first throat swab I had ever attempted, so had no idea what baseline looks like.FDA doesn't allow throat swabs for RATs, maybe because acidic solutions (Coke, coffee, documented on Twitter) can give [... want %more?] → https://twitter.com/michaelzlin/status/155857313502829772800:01
BrainstormNew from COVID on Twitter: Michael Lin, MD PhD   (@michaelzlin): Now was sure I had COVID-19. Luckily I was home alone at the time. And since leaving the meeting, indeed because there were known positives there, I had only met other people when outdoors and masked to minimize any transmission risk. → https://twitter.com/michaelzlin/status/155857599832027136000:11
BrainstormNew from COVID on Twitter: Michael Lin, MD PhD   (@michaelzlin): Also I had joint pains with the fever that went away around the same time.For the next 2 days, I had a mild runny nose. Nasal swab stayed positive as expected. Throat swab stayed negative. (BTW the negative throat swabs show that the earlier faint [... want %more?] → https://twitter.com/michaelzlin/status/155857991532625510400:29
BrainstormNew from COVID on Twitter: Michael Lin, MD PhD   (@michaelzlin): Note Paxlovid does help clear virus faster. This was seen in the trials. But also Biden was antigen-negative after 5 days Pax, which he started on day 1 of a positive nasal RAT, whereas it took me 9 days from my first positive nasal swab [... want %more?] → https://twitter.com/michaelzlin/status/155858338330268876800:39
BrainstormUpdates for Algeria: +142 cases since 22 hours ago01:03
BrainstormNew from COVID on Twitter: Michael Lin, MD PhD   (@michaelzlin): 3. Pax would have made little difference for my particular disease course — I couldn't prove myself COVID19+ until the positive nasal RAT on the same day as the fever. If I had gotten a PCR test the day I returned home, the result would arrive on [... want %more?] → https://twitter.com/michaelzlin/status/155858907997701734401:07
BrainstormNew from COVID on Twitter: Michael Lin, MD PhD   (@michaelzlin): But I'm glad I gave my vaccine-stimulated immune system a chance to clear SARSCoV2 on its own. This way I didn't have to worry about rebound, something that happens in >50% of cases with current prescribing practices. And I now should have good [... want %more?] → https://twitter.com/michaelzlin/status/155859119054236467301:16
BrainstormNew from COVID on Twitter: (translated) Marc Veldhoen (@Marc_Veld): Extreme right-wing parties and supporters are very active in promoting misinformation. High misinformation activity was noticeable during the elections: about COVID-19 and conspiracy theories. FB did nothing about this: but made almost €200,000 in [... want %more?] → https://twitter.com/Marc_Veld/status/155859731972093133001:35
BrainstormNew from COVID on Twitter: Michael Lin, MD PhD   (@michaelzlin): However, the secondary household attack rate during one unmasked disease course is less than <50% even for BA.2. My guess is it's because family members are not often talking loudly and closely to each other medrxiv.org/content/10.110… → https://twitter.com/michaelzlin/status/155860229454277427302:02
BrainstormNew from COVID on Twitter: Michael Lin, MD PhD   (@michaelzlin): Now was pretty sure I had COVID-19. Luckily I was home alone at the time. And since leaving the meeting, indeed because there were known positives there, I had only met other people when outdoors and in my N95 to minimize any transmission risk. → https://twitter.com/michaelzlin/status/155860675610786611202:12
BrainstormNew from COVID on Twitter: (translated) Marc Veldhoen (@Marc_Veld): If you think SC2 is not a problem but vaccination is, then you are assuming that the overwhelming majority of relevant experts, with knowledge, all data and methods, are wrong. Remember that without that knowledge it is very likely that you are wrong. → https://twitter.com/Marc_Veld/status/155860871025931059302:21
BrainstormNew from COVID on Twitter: Michael Lin, MD PhD   (@michaelzlin): But I was fortunate, and my vaccine-stimulated immune system had no trouble clearing SARSCoV2 on its own. Now I don't have to worry about rebound extending my infectious period, something that happens in >50% of cases with Paxlovid. And I should have [... want %more?] → https://twitter.com/michaelzlin/status/155861271496814182702:41
BrainstormUpdates for Jamaica: +183 cases, +2 deaths, +1147 tests since 23 hours ago03:01
BrainstormNew from COVID on Twitter: Rick Bright (@RickABright): When Will the Pandemic End? Great question.An excellent discussion in @nytimes @nytopinion w/ @JenniferNuzzo @VirusesImmunity @PepperMarion A few excerpts, mashups & extrapolations below. /1nytimes.com/2022/08/12/opi… → https://twitter.com/RickABright/status/155861445706406297803:18
ptcopHello04:01
BrainstormNew from This Week In Virology: TWiV 927: Merchlinsky vs monkeypox: Michael Merchlinsky joins TWiV to discuss the development of two smallpox antiviral drugs and two smallpox vaccines and their uses during the monkeypox outbreak. → https://www.microbe.tv/twiv/twiv-927/06:14
BrainstormUpdates for Florida, United States: +70536 cases, +3 deaths since 23 hours ago — Mexico City, Mexico: +9007 cases, +32 deaths since 3 days ago — Kagoshima, Japan: +3967 cases, +9 deaths since 23 hours ago — Gifu, Japan: +3855 cases, +3 deaths since 23 hours ago08:07
BrainstormNew from COVID on Twitter: Michael Lin, MD PhD   (@michaelzlin): Hearing Canada and UK allow throat swabs for antigen testing. Just another way FDA somehow sees the science differently from otherstwitter.com/US_FDA/status/… → https://twitter.com/michaelzlin/status/155870683029281587208:53
BrainstormNew from r/Coronavirus: Daily Discussion Thread | August 14, 2022: Please refer to our Wiki for more information on COVID-19 and our sub. You can find answers to frequently asked questions in our FAQ , where there is valuable information such as our: → https://old.reddit.com/r/Coronavirus/comments/wnzyd7/daily_discussion_thread_august_14_2022/09:02
BrainstormNew from Science-Based Medicine: Advice for the “Urgency of Normal” Team: Reasonable people won't believe things are normal until you stop talking about COVID. The post  first appeared on Science-Based Medicine . → https://sciencebasedmedicine.org/advice-for-the-urgency-of-normal-team/09:11
BrainstormUpdates for Taiwan: +21074 cases, +22 deaths, +41937 tests since 23 hours ago10:05
BrainstormNew from COVID on Twitter: Tom Wenseleers (@TWenseleers): Unlike what had long been assumed, the vaccine strain used to vaccinate against smallpox was not derived from cowpox. Where the strain came from we still don't know - it's never been found in the wild. That would no longer fly today. Yet, this is how we [... want %more?] → https://twitter.com/TWenseleers/status/155873264439695769810:35
BrainstormNew from COVID on Twitter: Tom Wenseleers (@TWenseleers): Anyone seen an attenuated virus Covid vaccine yet? Looked so easy though... And in the meantime practically everyone was exposed to the non-attenuated wild type virus. Pretty sure that was less safe. ncbi.nlm.nih.gov/pmc/articles/P… → https://twitter.com/TWenseleers/status/155875386180393779411:59
BrainstormNew from Reddit (test): 14/08/22 - ZOE COVID-19 Study Update: 2,089,367 people are currently predicted to have symptomatic COVID-19 in the UK, down by 67,244. Yesterday was 2,156,611 (-3%) and last Sunday was 2,741,470 (-24%). → https://old.reddit.com/r/CoronavirusUK/comments/wo2ral/140822_zoe_covid19_study_update/12:08
BrainstormUpdates for Russia: +28982 cases, +54 deaths since a day ago — Qatar: +748 cases since 21 hours ago13:06
BrainstormUpdates for UAE: +822 cases, +217065 tests since 23 hours ago14:02
BrainstormNew from Reddit (test): nCoV: Global COVID Cases For 14AUG22 → https://old.reddit.com/r/nCoV/comments/wo5kyr/global_covid_cases_for_14aug22/14:47
BrainstormNew from r/COVID19: COVID19: Interferon-alpha or -beta facilitates SARS-CoV-2 pulmonary vascular infection by inducing ACE2 → https://old.reddit.com/r/COVID19/comments/wo6eke/interferonalpha_or_beta_facilitates_sarscov2/15:34
BrainstormUpdates for Marshall Is.: +569 cases since a day ago17:08
BrainstormNew from r/COVID19: COVID19: The mechanism underlying extrapulmonary complications of the coronavirus disease 2019 and its therapeutic implication → https://old.reddit.com/r/COVID19/comments/wo8okk/the_mechanism_underlying_extrapulmonary/17:18
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): The @uscensusbureau data for #LongCovidSelf-reported, without controls, or pre-Covid baseline symptoms like the new Netherlands study (12% prevalence) thelancet.com/journals/lance…But, no matter how you look at it, it's affecting a substantial number of people [... want %more?] → https://twitter.com/EricTopol/status/155884729365404876818:14
BrainstormNew from r/COVID19: COVID19: Mediators of Obesity Do Not Influence SARS-CoV-2 Infection or Activation of Primary Human Lung Microvascular Endothelial Cells In Vitro → https://old.reddit.com/r/COVID19/comments/woac1a/mediators_of_obesity_do_not_influence_sarscov2/18:33
BrainstormNew from WebMD: Four Cruise Lines to Drop COVID Vaccination Requirements: Four major cruise lines are dropping their COVID-19 vaccination requirements for some sailings next month, according to USA Today. → https://www.webmd.com/lung/news/20220814/four-cruise-lines-to-drop-covid-vaccination-requirements18:43
BrainstormUpdates for Italy: +19455 cases, +78 deaths since 23 hours ago19:01
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): The rise of BA.2.75 has been studied very carefully by @TWenseleers and its trajectory may vary considerably between countries. Or we could see a co-dominance pattern, something that hasn't occurred yet /9 pic.twitter.com/myYGLCDDGg → https://twitter.com/EricTopol/status/155886844822607052819:40
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): This week a new post-Covid brain MRI study was published, without baseline images and not as large as the best study to date by @uk_biobank I've compared them herepnas.org/doi/full/10.10… @PNASNews nature.com/articles/s4158… @nature pic.twitter.com/5zXZ0csnLV → https://twitter.com/EricTopol/status/155888382164207616020:37
LjL<Brainstorm> New from WebMD: Four Cruise Lines to Drop COVID Vaccination Requirements: Four major cruise lines are dropping their COVID-19 vaccination requirements for some sailings next month, according to USA Today. → https://www.webmd.com/lung/news/20220814/four-cruise-lines-to-drop-covid-vaccination-requirements20:41
LjL:|20:41
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): For the multitude of people who think mild cases of Covid are totally meaningless, these results would beg to differ. Yes, it's a short-term effect so far and may be partially reversed over time. Yes, likely to be less w/ current variants and vaccination. But denial [... want %more?] → https://twitter.com/EricTopol/status/155889125160413593721:06
Hethan[m]100% DISCRETE AND GUARANTEED TO ALL STATES... (full message at https://libera.ems.host/_matrix/media/r0/download/libera.chat/b6908089c934580f89a830b1e76d870605f0d128)21:50
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): The formidable challenge of BA.5 doesn't detract from the outstanding containment of the virus and high adoption of vaccines in these countries, with a 6-11 fold reduction of cumulative mortality per capita compared with the United States@OurWorldInData pic.twitter.com/00wQpIlJ3T → https://twitter.com/EricTopol/status/155890181843589939221:53
BrainstormNew from r/COVID19: COVID19: Human pulmonary artery endothelial cells upregulate ACE2 expression in response to iron-regulatory elements: Potential implications for SARS-CoV-2 infection → https://old.reddit.com/r/COVID19/comments/wof3db/human_pulmonary_artery_endothelial_cells/22:02
BrainstormNew from Reddit (test): nCoV: Why have so many African leaders died of COVID-19? | Twenty-four (24) Heads of State & Ministerial (cabinet) level deaths worldwide. Seventeen (17) of them happened in Africa (as of 04AUG2021)| 17MAY21 → https://old.reddit.com/r/nCoV/comments/wofmwj/why_have_so_many_african_leaders_died_of_covid19/22:21
BrainstormNew from COVID on Twitter: Michael Lin, MD PhD   (@michaelzlin): Thus the COVID+ group is enriched for patients who believe they have COVID-related neurological problems compared to all COVID patients, plus this was pre-vaccine, plus they're not blinded. This is fine as long as we don't generalize findings to all [... want %more?] → https://twitter.com/michaelzlin/status/155892482998562406423:17
BrainstormNew from COVID on Twitter: Michael Lin, MD PhD   (@michaelzlin): The COVID+ group is also enriched for other psych Dx. There may be some self-selection going on where those with conditions and COVID+ are more likely to volunteer, but those prev conditions and no COVID are less likely (maybe thinking they don't [... want %more?] → https://twitter.com/michaelzlin/status/155892716456465612923:26
BrainstormNew from COVID on Twitter: Michael Lin, MD PhD   (@michaelzlin): Indeed 62/81 = 77% of COVID+ subjects had anosmia; this is much higher than the 20% reported in 2021 and the 5% reported in 2022.Why is unclear. Did the study ad mention anosmia? Ad not shown; would be nice if all human volunteer studies showed [... want %more?] → https://twitter.com/michaelzlin/status/155893079413496627223:45
BrainstormNew from COVID on Twitter: Michael Lin, MD PhD   (@michaelzlin): The other major finding is in the postmortem tissue SARSCoV2 is found mostly in astrocytes, and that infection alters the expression of proteins involved in energy metabolism. This would be consistent with the idea of metabolic demands making the left [... want %more?] → https://twitter.com/michaelzlin/status/155893427756730368023:54

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