libera/##covid-19/ Thursday, 2022-08-25

BrainstormUpdates for Marshall Is.: +2613 cases since a day ago00:03
BrainstormNew from Reddit (test): CoronaVirus_2019_nCoV: Moderna Completes Application To U.S. Food And Drug Administration For Emergency Use Authorization Of Omicron-Targeting Bivalent Covid-19 Booster Vaccine, mRNA-1273.222 → https://old.reddit.com/r/CoronaVirus_2019_nCoV/comments/wwwhvo/moderna_completes_application_to_us_food_and_drug/00:18
BrainstormNew from ##covid-19 Zotero group: Regular asymptomatic testing paused in additional settings: Type Web Page URL https://www.gov.uk/government/news/regular-asymptomatic-testing-paused-in-additional-settings Accessed 2022-08-24 22:53:55 Language en Abstract Regular asymptomatic testing for Covid will be paused in all [... want %more?] → https://www.zotero.org/groups/covid_links/items/SVW8PZBC00:56
BrainstormUpdates for United States: +120953 cases, +449 deaths since 23 hours ago — Brazil: +18277 cases, +136 deaths since 22 hours ago01:05
BrainstormNew from Ars Technica: Science: Dr. Oz emailed Trump admin. to push notoriously useless COVID treatment → https://arstechnica.com/?p=187599901:24
BrainstormNew from COVID on Twitter: Michael Lin, MD PhD   (@michaelzlin): Correction: Bourla has a PhD in biotech. So he would know what he's talking about, except as a CEO he won't and probably can't present any data other than those that make Pfizer look good → https://twitter.com/michaelzlin/status/156258410312743731201:43
LjL<Brainstorm> New from Ars Technica: Science: Dr. Oz emailed Trump admin. to push notoriously useless COVID treatment → https://arstechnica.com/?p=187599902:06
BrainstormUpdates for Canada: +3776 cases, +82 deaths since 23 hours ago02:07
BrainstormUpdates for Norway: +153 cases since 23 hours ago — United Kingdom: +351 deaths since 6 hours ago03:03
BrainstormNew from Reddit (test): CoronaVirus_2019_nCoV: COVID has evolved to make you sicker quicker, new study finds → https://old.reddit.com/r/CoronaVirus_2019_nCoV/comments/wx0rly/covid_has_evolved_to_make_you_sicker_quicker_new/04:06
BrainstormUpdates for Thailand: +2002 cases, +29 deaths since 23 hours ago05:02
BrainstormNew from COVID on Twitter: Michael Lin, MD PhD   (@michaelzlin): Correction: Bourla has a PhD in biotech. So he should understand what he's talking about, except as a CEO he won't and probably can't present any data other than those that make Pfizer look good → https://twitter.com/michaelzlin/status/156263986307716300805:21
BrainstormNew from COVID on Twitter: Michael Lin, MD PhD   (@michaelzlin): In 40-64yo, hospitalizations due to Covid-19 were 15.2 per 100k person-days with Paxlovid vs 15.8 cases without (ratio 0.74; 95% CI, 0.35 to 1.58). The ratio for death due to Covid-19 was 1.32 (95% CI, 0.16 to 10.75).So no benefit for [... want %more?] → https://twitter.com/michaelzlin/status/156264261387791155205:30
BrainstormNew from COVID on Twitter: Michael Lin, MD PhD   (@michaelzlin): So how did we get into this situation where everybody is popping Paxlovid like aspirin and rebounding like Bill Russell? Because of Test to Treat, aka Unnecessary Gift to Pfizer pic.twitter.com/L6F5d56Ait → https://twitter.com/michaelzlin/status/156264400884470169605:40
BrainstormUpdates for Germany: +49201 cases, +116 deaths since a day ago — Antigua and Barb.: +54 cases, +1 deaths since 6 days ago06:10
BrainstormNew from BBC Health: (news): Tory leadership: Rishi Sunak criticises government Covid response → https://www.bbc.co.uk/news/uk-politics-6266453706:36
BrainstormUpdates for Tokyo, Japan: +25444 cases, +22 deaths since 23 hours ago — Aichi, Japan: +18199 cases, +27 deaths since 23 hours ago — Hyogo, Japan: +11450 cases, +12 deaths since 23 hours ago — Saitama, Japan: +10912 cases, +19 deaths since 23 hours ago08:02
BrainstormNew from EMA: What's new: Document: Spikevax (previously COVID-19 Vaccine Moderna)-H-C-PSUSA-00010897-202112: EPAR - Scientific conclusions and grounds for the variation to the terms of the marketing authorisation → https://www.ema.europa.eu/documents/scientific-conclusion/spikevax-previously-covid-19-vaccine-moderna-h-c-psusa-00010897-202112-epar-scientific-conclusions_en.pdf09:08
BrainstormNew from EMA: Human medicine assessment reports: (news): Human medicines European public assessment report (EPAR): Spikevax (previously COVID-19 Vaccine Moderna), elasomeran,COVID-19 mRNA vaccine (nucleoside-modified), COVID-19 virus infection, Date of authorisation: 06/01/2021, Revision: 27, Status: Authorised → https://www.ema.europa.eu/en/medicines/human/EPAR/spikevax09:46
BrainstormUpdates for Taiwan: +27227 cases, +37 deaths, +57257 tests since 23 hours ago10:07
BrainstormNew from COVID on Twitter: Marc Veldhoen (@Marc_Veld): There is evidence that having two infections, one with a pre-Omicron variant followed by one with an Omicron subvariant, elicits stronger protection against future Omicron-subvariant reinfection than having had only one infection with an Omicron subvariant. → https://twitter.com/Marc_Veld/status/156271399797539225610:14
BrainstormNew from StatNews: A pandemic push for data sharing could pay off for pregnancy research: Covid-19 pushed researchers to make use of real-world data. In pregnancy research, that could pay dividends far beyond the pandemic. → https://www.statnews.com/2022/08/25/pregnancy-data-maternal-health-research/10:42
BrainstormNew from COVID on Twitter: Marc Veldhoen (@Marc_Veld): IgG antibodies to SARS-CoV-2 in asymptomatic blood donors at two-time points in KarachiGreat work from @Zahra_Hasan20 and the team! Congrats!journals.plos.org/plosone/articl… → https://twitter.com/Marc_Veld/status/156272891397706137811:21
BrainstormNew from COVID on Twitter: Tom Wenseleers (@TWenseleers): @Tuliodna @tomtom_m @SACEMAdirector Maybe by including additional covariates that reflect that in the mortality model, e.g. waiting times at emergency care, etc? Method above should in large part deal with this, since any excess that doesn't correlate [... want %more?] → https://twitter.com/TWenseleers/status/156273631506165350411:50
BrainstormUpdates for Russia: +43919 cases, +71 deaths since 23 hours ago — Afghanistan: +382 cases, +2 deaths, +1820 tests since 23 hours ago11:59
BrainstormNew from Reddit (test): 25/08/22 - ZOE COVID-19 Study Update: 1,634,686 people are currently predicted to have symptomatic COVID-19 in the UK, down by 24,370. Yesterday was 1,659,056 (-1%) and last Thursday was 1,869,335 (-13%). → https://old.reddit.com/r/CoronavirusUK/comments/wxa13a/250822_zoe_covid19_study_update/12:28
BrainstormNew from BBC Health: Covid booster: Who will get another jab this autumn?: Over-50s can have another Covid booster, and younger people who are at higher risk and NHS staff. → https://www.bbc.co.uk/news/health-5504563912:37
BrainstormNew from COVID on Twitter: Marc Veldhoen (@Marc_Veld): But; No evidence of benefit was found in younger adults 40-65.109,254 patients met the eligibility criteria, of whom 3902 (4%) received nirmatrelvir during the study period; during the Omicron wave. pic.twitter.com/7SyrQ3u26j → https://twitter.com/Marc_Veld/status/156275237260219596812:46
BrainstormNew from COVID on Twitter: Marc Veldhoen (@Marc_Veld): Another confirmation: During a wave of SARS-CoV-2 omicron BA.2, initiation of novel oral antiviral treatments in hospitalised patients not requiring oxygen therapy on admission showed substantial clinical benefit. pic.twitter.com/KfRm5Eglku → https://twitter.com/Marc_Veld/status/156275487108578099212:56
BrainstormNew from Reddit (test): nCoV: Global COVID Cases For 25AUG22 → https://old.reddit.com/r/nCoV/comments/wxbke8/global_covid_cases_for_25aug22/13:24
BrainstormNew from COVID on Twitter: Gunhild Alvik Nyborg (@GANyborg): Today, in 2 hours (4 pm Central European Time/10 am Eastern Time) Twitter Spaces event where you can hear @drclairetaylor and @Sunny_Rae1 in dialogue on the clinicians' perspective of #LongCovid. Tune in! twitter.com/TheWHN/status/… → https://twitter.com/GANyborg/status/156277193982726554014:04
BrainstormNew from Reddit (test): nCoV: Counties with highest COVID-19 infection rates in Missouri | 25AUG22 → https://old.reddit.com/r/nCoV/comments/wxd9cx/counties_with_highest_covid19_infection_rates_in/14:44
BrainstormUpdates for Indonesia: +5214 cases, +19 deaths, +99226 tests since a day ago — UAE: +593 cases, +236071 tests since a day ago15:06
BrainstormNew from StatNews: Pharma: STAT+: Pharmalittle: House report shows Trump sought to pressure FDA on Covid response; Pfizer Covid pill provides little benefit to younger adults → https://www.statnews.com/pharmalot/2022/08/25/trump-covid-pfizer-fda-novartis-vaccines-monkeypox/15:24
BrainstormNew from EMA: What's new: Medicine: Human medicines European public assessment report (EPAR): Spikevax (previously COVID-19 Vaccine Moderna), elasomeran,COVID-19 mRNA vaccine (nucleoside-modified), COVID-19 virus infection, Date of authorisation: 06/01/2021, Revision: 27, Status: Authorised → https://www.ema.europa.eu/en/medicines/human/EPAR/spikevax15:54
BrainstormUpdates for Hong Kong: +8579 cases, +9 deaths since a day ago — China: +4407 cases since 2 months ago — United Kingdom: +4971 deaths since 20 hours ago16:08
BrainstormNew from r/COVID19: COVID19: Replicating RNA platform enables rapid response to the SARS-CoV-2 Omicron variant and elicits enhanced protection in naïve hamsters compared to ancestral vaccine → https://old.reddit.com/r/COVID19/comments/wxffsm/replicating_rna_platform_enables_rapid_response/16:24
BrainstormNew from ClinicalTrials.gov: (news): Prospective Monitoring of BNT162b2 Second Vaccination Booster Effects in Health Care Workers (HCW) → https://clinicaltrials.gov/ct2/show/NCT0551645917:02
BrainstormNew from ClinicalTrials.gov: (news): Evaluation of Molecular Point-of-care Xpert  Xpress SARS-CoV-2 Detection Implementation in Resource-limited Settings → https://clinicaltrials.gov/ct2/show/NCT0551488617:12
BrainstormNew from ClinicalTrials.gov: (news): Resilience Intervention for Health Professionals COVID-19 → https://clinicaltrials.gov/ct2/show/NCT0551517217:32
BrainstormNew from ClinicalTrials.gov: (news): The COVID-19 Pandemic Process Increase Latex Glove Use and Latex Allergy Complaints in Hospital Nurses? Survey Study → https://clinicaltrials.gov/ct2/show/NCT0551527617:42
BrainstormNew from ClinicalTrials.gov: (news): Study to Assess Efficacy and Safety of Treamid for Patients With Reduced Exercise Tolerance After COVID-19 → https://clinicaltrials.gov/ct2/show/NCT0551655018:02
BrainstormUpdates for Italy: +23435 cases, +84 deaths since 22 hours ago — Canada: +3670 cases, +52 deaths since 19 hours ago18:07
BrainstormNew from ClinicalTrials.gov: (news): Phase 2a Trial to Evaluate Safety and Immunogenicity of COVID-19 Vaccine Strategies in HIV-infected/Uninfected Adults. → https://clinicaltrials.gov/ct2/show/NCT0551504218:12
BrainstormNew from BMJ: Covid-19: Asymptomatic testing is “paused” in England’s hospitals and care homes: Regular asymptomatic testing for covid-19 in hospitals, care homes, and hospices in England will be “paused” from 31 August, the Department of Health and Social Care has said.Testing will also be halted in prisons and [... want %more?] → http://www.bmj.com/content/378/bmj.o2099.short18:32
BrainstormNew from Reddit (test): CoronaVirus_2019_nCoV: BA.5 COVID Boosters Are Coming Soon → https://old.reddit.com/r/CoronaVirus_2019_nCoV/comments/wxiw0q/ba5_covid_boosters_are_coming_soon/18:41
BrainstormNew from CIDRAP: Study shows outsized COVID impact on community hospitals: Chris Dall | News Reporter | CIDRAP News Aug 25, 2022 Central line-associated bloodstream infections, ventilator-associated events, and C difficile infections all increased. → https://www.cidrap.umn.edu/news-perspective/2022/08/study-shows-outsized-covid-impact-community-hospitals18:51
BrainstormNew from Reddit (test): nCoV: Pandemic response in Mayotte: How approaches need to be adapted to local community needs | 25AUG22 → https://old.reddit.com/r/nCoV/comments/wxjf4r/pandemic_response_in_mayotte_how_approaches_need/19:01
BrainstormNew from COVID on Twitter: (translated) Marc Veldhoen (@Marc_Veld): One of the most important ways to reduce the risk of LC is to get all the recommended vaccines. The vaccine not only reduces the risk of contracting Covid-19, but it also reduces the chance of LC through improved immunity. → https://twitter.com/Marc_Veld/status/156284707434937959019:10
BrainstormNew from COVID on Twitter: Tulio de Oliveira (@Tuliodna): This kind of results make our team really proud! We worked with Egyptian scientists to help them to do their own paper and analysis! SARS-CoV-2 Genetic Diversity and Lineage Dynamics in Egypt during the First 18 Months of the Pandemic mdpi.com/1795678 #mdpiviruses → https://twitter.com/Tuliodna/status/156285054361758515319:20
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): The rate of asymptomatics for current infectious disease of interestPolio ~70%cdc.gov/vaccines/pubs/….Covid ~30%acpjournals.org/doi/10.7326/m2…Monkeypox ?% (cases documented)acpjournals.org/doi/10.7326/M2… → https://twitter.com/EricTopol/status/156285883735429939519:49
ublx%title https://www.cnbc.com/2022/08/20/omicron-specific-booster-shots-are-weeks-away-eligibility-guide.html19:56
Brainstormublx: From www.cnbc.com: Omicron-specific booster shots are weeks away: Eligibility guide19:56
ublx^ "... if you're unvaccinated, you won't be eligible for the updated formula until you complete a primary series with the existing Covid vaccines."19:56
BrainstormUpdates for Chile: +9249 cases, +67 deaths, +81447 tests since a day ago19:59
BrainstormNew from COVID on Twitter: Tulio de Oliveira (@Tuliodna): We got over 100 African and Latin America that spend time in our lab in the last 2 years. Having so many amazing scientists inspire our people to work hard to respond to the pandemic. → https://twitter.com/Tuliodna/status/156286095806983782419:59
LjLublx, bit mean, but20:01
ublxmoot?20:01
LjLif there is more demand than offer, then fuck the unvaccinated20:01
LjLif there is more offer than demand, then give it to them20:01
ublxam seeing someone making the comment that boosters use about 20% of the material of full original shot, and supposing that if the update formula is designed to apply likewise, it may not function well on its own20:03
LjLraw material is not the only factor20:04
LjLthe updated formula, afaik, is going to be used as a bivalent vaccine20:05
LjLi.e. there will be some of the original too20:05
BrainstormNew from The Atlantic: America’s Fall Booster Plan Has a Fatal Paradox: America’s first-ever reformulated COVID-19 vaccines are coming, very ahead of schedule, and in some ways, the timing couldn’t be better. Pfizer’s version of the shot, which combines the original recipe [... want %more?] → https://www.theatlantic.com/health/archive/2022/08/omicron-booster-vaccine-only-plan/671233/20:50
BrainstormUpdates for United Kingdom: +12233 deaths since 22 hours ago — Mali: +15 cases, +818 tests since 22 hours ago21:01
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): If you look at the spike mutation map for BA.5 and compare it to Alpha, the first major variant, it's striking how well vaccines have held up vs severe disease, and not surprising why it has been harder to suppress infections and [... want %more?] → https://twitter.com/EricTopol/status/156287804326519603221:10
BrainstormNew from StatNews: Fauci’s non-retirement, grading biotech VCs, & a bellwether IPO: Are we getting Covid-19 boosters wrong? Which venture capitalists are missing their marks? And what's Anthony Fauci's legacy? All that and more on the new episode of "The Readout LOUD"… → https://www.statnews.com/2022/08/25/podcast-fauci-steps-down-grading-biotech-vcs-bellwether-ipo/21:30
BrainstormUpdates for Georgia: +12595 cases since 7 days ago — France: +19893 cases, +44 deaths since 23 hours ago22:03
BrainstormNew from CIDRAP: Paxlovid, molnupiravir benefit older COVID-19 patients, 2 studies show: Mary Van Beusekom | News Writer | CIDRAP News Aug 25, 2022 The drugs reduced disease progression, hospitalization, and death in seniors. → https://www.cidrap.umn.edu/news-perspective/2022/08/paxlovid-molnupiravir-benefit-older-covid-19-patients-2-studies-show22:10
BrainstormNew from r/COVID19: COVID19: COVID-19 induces CNS cytokine expression and loss of hippocampal neurogenesis → https://old.reddit.com/r/COVID19/comments/wxoavt/covid19_induces_cns_cytokine_expression_and_loss/22:20
BrainstormNew from COVID on Twitter: Steve Miller (@SteveMillerOC): BrutalBut if the analogy is to PPP loan forgiveness, for which businesses were required to maintain employment levels and pay during lockdown,Why aren’t we imposing requirements on students who seek loan forgiveness? twitter.com/whitehouse/sta… → https://twitter.com/SteveMillerOC/status/156291912080635494423:49
BrainstormNew from COVID on Twitter: Nick Felker,       (@HandNF): "It’s actually striking that in 2 months from the June 28th FDA meeting, there is a BA.5 vaccine booster made at scale. That is finally in keeping with all the excitement about the plasticity of the mRNA vaccine platform" -@EricTopolerictopol.substack.com/p/the-imminent… → https://twitter.com/HandNF/status/156292055566959411223:59

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