| Brainstorm | Updates for India: +2587 cases since 23 hours ago | 00:07 |
|---|---|---|
| Brainstorm | New from The Lancet (Online): [Department of Error] Department of Error: WHO Solidarity Trial Consortium. Remdesivir and three other drugs for hospitalised patients with COVID-19: final results of the WHO Solidarity randomised trial and updated meta-analyses. Lancet 2022; 399: [... want %more?] → https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(22)01993-6/fulltext | 00:32 |
| LjL | uh, full text not actually available | 00:40 |
| LjL | is the COVID emergency "over" to the point we go back to paywalls for papers? | 00:40 |
| Brainstorm | New from COVID on Twitter: Scott Gottlieb, MD (@ScottGottliebMD): “Combined, the two new strains make up the largest proportion of infections in the New York and New Jersey region. Around 20% of infections there are already from BQ.1 or BQ.1.1, CDC estimates.” Level 5 and 6 variants now total about 10% of [... want %more?] → https://twitter.com/ScottGottliebMD/status/1581056521089138688 | 01:00 |
| Brainstorm | Updates for Guatemala: +1026 cases, +2 deaths since 18 hours ago | 02:05 |
| Brainstorm | Updates for Brazil: +6318 cases, +42 deaths since 2 hours ago | 03:07 |
| Brainstorm | Updates for Germany: +91508 cases, +160 deaths since 23 hours ago — Eq. Guinea: +35 cases since 2 days ago | 04:59 |
| Brainstorm | New from Reddit (test): CoronaVirus_2019_nCoV: Distressing Study On Long COVID-19 Reveals Just How Enduring It Can Be → https://old.reddit.com/r/CoronaVirus_2019_nCoV/comments/y4c65d/distressing_study_on_long_covid19_reveals_just/ | 05:08 |
| Brainstorm | New from Reddit (test): CoronaVirus_2019_nCoV: "Pretty troublesome": New COVID variant BQ.1 now makes up 1 in 10 cases nationwide, CDC estimates → https://old.reddit.com/r/CoronaVirus_2019_nCoV/comments/y4cjzu/pretty_troublesome_new_covid_variant_bq1_now/ | 05:18 |
| Brainstorm | New from This Week In Virology: TWiV 945: Clinical update with Dr. Daniel Griffin: In his weekly clinical update Dr. Griffin discusses a healthcare-associated infection with Monkeypox virus, air and surface sampling for monkeypox virus in a UK hospital, misrepresentation and nonadherence regarding COVID19 public health [... want %more?] → https://www.microbe.tv/twiv/twiv-945/ | 06:15 |
| Brainstorm | New from COVID on Twitter: Tulio de Oliveira (@Tuliodna): As we finish a week of training in Senegal, 5 of our team go to Berlin to attend the World Health Summit, followed by a collaborative visit to Oxford, U.K. We are really working hard to build global collaboration to save lives & prevent epidemics. [... want %more?] → https://twitter.com/Tuliodna/status/1581139400024416256 | 06:34 |
| Brainstorm | Updates for Andalusia, Spain: +2335 cases, +29 deaths since 7 days ago — Zuid-Holland, Netherlands: +2285 cases, +6 deaths since 3 days ago — Castile y Leon, Spain: +2141 cases, +5 deaths since 7 days ago — Metropolitana, Chile: +2081 cases, +9 deaths since 23 hours ago | 08:06 |
| Brainstorm | New from r/Coronavirus: Daily Discussion Thread | October 15, 2022: Please refer to our Wiki for more information on COVID-19 and our sub. You can find answers to frequently asked questions in our FAQ , where there is valuable information such as our: → https://old.reddit.com/r/Coronavirus/comments/y4h1g5/daily_discussion_thread_october_15_2022/ | 09:05 |
| Brainstorm | New from Politico: EU prosecutor’s office opens investigation into COVID vaccine purchases: The EPPO didn't specify who was being investigated, or which of the EU's vaccine contracts are under scrutiny. → https://www.politico.eu/article/ursula-von-der-leyen-pfizer-eu-prosecutors-office-opens-investigation-into-covid-vaccine-purchases/ | 10:39 |
| Brainstorm | New from COVID on Twitter: Marc Veldhoen (@Marc_Veld): Severe COVID-19 outcomes after full vaccination of primary schedule and initial boosters: pooled analysis of national prospective cohort studies of 30 million individuals in England, Northern Ireland, Scotland, and Wales thelancet.com/journals/lance… → https://twitter.com/Marc_Veld/status/1581223233273368577 | 12:04 |
| Brainstorm | New from COVID on Twitter: Tulio de Oliveira (@Tuliodna): A global health summit in Berlin and the director of AfricaCDC who is a keynote speaker is not allowed to enter Europe in spite of having a valid visa. In this thread he also comment that the opposite was true with vaccines and diagnostics that could not leave [... want %more?] → https://twitter.com/Tuliodna/status/1581233517366607874 | 12:51 |
| Brainstorm | Updates for Hong Kong: +5424 cases, +7 deaths since 23 hours ago | 13:05 |
| Brainstorm | New from r/COVID19: COVID19: 'Breathless' investigates the origins of COVID-19 and other pandemic science. → https://old.reddit.com/r/COVID19/comments/y4laa9/breathless_investigates_the_origins_of_covid19/ | 13:19 |
| Brainstorm | New from Reddit (test): nCoV: Global COVID Cases For 15OCT22 → https://old.reddit.com/r/nCoV/comments/y4lop3/global_covid_cases_for_15oct22/ | 13:38 |
| Brainstorm | Updates for Japan: +28709 cases, +67 deaths since 2 hours ago — China: +5785 cases, +7 deaths since 20 hours ago — Nepal: +45 cases since a day ago — Malta: +22 cases, +496 tests since a day ago | 14:07 |
| Brainstorm | New from r/COVID19: COVID19: Optic nerve sheath diameter is associated with outcome in severe Covid-19 → https://old.reddit.com/r/COVID19/comments/y4nrb5/optic_nerve_sheath_diameter_is_associated_with/ | 15:23 |
| de-facto | https://www.thetimes.co.uk/article/chemists-to-prescribe-antibiotics-under-coffey-health-plan-gjvfnb6q5 | 15:41 |
| de-facto | what could possibly go wrong with giving antibiotics to everyone who asks for it, without consulting a MD? | 15:41 |
| de-facto | oh wait there was something... | 15:42 |
| spybert | They do have to consult the pharmacist, so it's not that bad. | 16:02 |
| spybert | In the US you have a lot of people ordering veterinary antibiotics online because medical care is so ridiculously expensive. | 16:04 |
| de-facto | the pharmacist does not have the knowledge to give them proper advise if their medical condition (and variant of microorganism) is suitable for treatment with antibiotics. also its the pharmacist that profits from selling | 16:05 |
| de-facto | antibiotics simply should not be available for people unaware of their exact medical condition | 16:05 |
| spybert | Why would you even need something like that in the UK anyway? Don't they have national health insurance | 16:06 |
| de-facto | otherwise people will just go for cheap options and take them into the blue, the more the better, maybe they are lucky and some of them still work | 16:06 |
| spybert | At least, in the US case, pharmacists could inform the patients that certain antibiotics are unsuitable for children, etc. | 16:07 |
| de-facto | when people are not feeling well, they should not just be able to go to a pharmacist and ask for the same antibiotic that their aunt told them helped her back when she had a headache | 16:07 |
| de-facto | lol well its about massively increasing the missuse of antibiotics, raising the natural selection bias of many (potentially even non-harmful) microorganisms to build resistent variants. microorganisms exchange gene material in nature, so eventually most of the pathogenic ones will have gained resistance | 16:09 |
| spybert | The pharmacist would provide a sanity check for cases like that, better than nothing. | 16:09 |
| de-facto | already the speed for new fully resistant microorganisms exceeds the speed of new antibiotics getting discovered, let alone developed (not much money in there anyhow) so giving them out basically freely to everyone asking a pharmacist will significantly increase that problem | 16:10 |
| de-facto | i doubt the pharmacist will do anything but sell those | 16:10 |
| de-facto | if its not him selling it, its the one next door | 16:10 |
| spybert | Well, in the US case you could limit which antibiotics the pharmacist could sell without prescription. In the UK, why would something like that even be needed? | 16:13 |
| de-facto | i am not sure, it does not make any sense to me entirely | 16:14 |
| de-facto | all i am sure about is that we urgently need to significantly *decrease* the usage of antibiotics if we want to have some available that still work in the near future | 16:16 |
| de-facto | this approach sounds like the opposite to me though | 16:16 |
| spybert | Most of the problem relates to factory farming, not human use | 16:16 |
| spybert | Why make things tough on the poor when agribusiness feweds tons of antibiotics to reduce feed requirements for farm animals? | 16:17 |
| de-facto | not sure about that, many hospitals already fight with an epidemic of multiresistant microorganisms, this only will make it worse (e.g. spreading them in schools and working places) | 16:18 |
| de-facto | but sure, antibiotics in farming also are a problem | 16:18 |
| spybert | But look where the resistant organisms usually originate. Farm animals | 16:18 |
| de-facto | plus using them will have an impact on the gastro-intestinal tract, killing parts of the microbiome, which is a significant part of the immune system capabilities (iirc something like 80% of immune system resources rely on an intact microbiome) | 16:19 |
| de-facto | so having killed and unbalanced the microbiome also will make hosts more vulnerable to viral infections etc | 16:20 |
| ublx | the times article notes the difference between the scottish and english case. from scotland myself, i hadn't realised that england doesn't have prescribing pharmacists | 16:25 |
| ublx | in scotland, wandering into a pharmacy, it seems you might have a fifty fifty chance of the pharmacist you see actually being a prescribing pharmacist. if a prescribing pharmacist is not on the premises, you won't be able to get anything not rated over-the-counter without a prescription | 16:26 |
| ublx | and just because the prescribing pharmacist can give you a wide range of prescriptions, doesn't mean they will | 16:27 |
| ublx | from the article, though, "said that she has previously handed out her own supplies of the medicines to friends and family who were feeling unwell." seems fairly outrageous. one wonders why she has personal supplies of antibiotics at all, never mind a sufficient quantity to pass a full course to other people | 16:31 |
| Brainstorm | New from r/COVID19: COVID19: Identifying pre-existing conditions and multimorbidity patterns associated with in-hospital mortality in patients with COVID-19 → https://old.reddit.com/r/COVID19/comments/y4pqhq/identifying_preexisting_conditions_and/ | 16:49 |
| Brainstorm | New from COVID on Twitter: Eric Topol (@EricTopol): "There are now 95 nasal vaccines under development around the world.... 6 have reached the final Phase 3 in clinical trials." None of those late trials are in the US. India and China already have approved nasal/inhaled vaccinespolitico.com/news/2022/10/1… [... want %more?] → https://twitter.com/EricTopol/status/1581304253003354113 | 17:27 |
| Brainstorm | New from COVID on Twitter: (translated) Marc Veldhoen (@Marc_Veld): Jan makes rarity a big thing. Because who knows... This is nonsense and speculation.Diversity? Yes.... 8 billion people. Where would it come from? No, not the vaccine Jan. pic.twitter.com/fZoyaDackI → https://twitter.com/Marc_Veld/status/1581323621024206848 | 18:44 |
| Brainstorm | Updates for Italy: +38968 cases, +73 deaths, +215672 tests since 23 hours ago — Sri Lanka: +19 cases, +1 deaths since a day ago | 18:59 |
| Brainstorm | New from BBC Health: BioNTech: Could Covid vaccine technology crack cancer?: BioNTech's mRNA cancer trials started long before the pandemic, and have shown some early encouraging signals. → https://www.bbc.co.uk/news/health-63247997 | 19:12 |
| Brainstorm | New from COVID on Twitter: Eric Topol (@EricTopol): The government's suppression of truth, how Dr. Wenliang was treated even before he got Covid, and important discrepancies are noted pic.twitter.com/q6uu7RioQ1 → https://twitter.com/EricTopol/status/1581332927895416832 | 19:22 |
| LjL | Brainstorm will go down for a while because I need to change RAM sticks around again, hopefully last time | 20:15 |
| Brainstorm | New from r/Coronavirus: Coronavirus: The CDC says the BQ.1 and BQ.1.1 variants are on the rise in the U.S. while the still-dominant BA.5 subvariant was 67.9% of total cases last week, down from 90% in August. → https://old.reddit.com/r/Coronavirus/comments/y4u1v2/the_cdc_says_the_bq1_and_bq11_variants_are_on_the/ | 20:19 |
| xx | I somehow totally missed that there's BQ.1.1 out there | 20:21 |
| Brainstorm | New from Reddit (test): CoronaVirus_2019_nCoV: Going long: The ravages of long COVID are coming into focus → https://old.reddit.com/r/CoronaVirus_2019_nCoV/comments/y4wrh2/going_long_the_ravages_of_long_covid_are_coming/ | 21:52 |
| Brainstorm | New from Reddit (test): CoronaVirus_2019_nCoV: BQ.1.1 is among the most immune-evasive COVID variants yet. It’s coming in hot in the U.S. → https://old.reddit.com/r/CoronaVirus_2019_nCoV/comments/y4wy0e/bq11_is_among_the_most_immuneevasive_covid/ | 22:02 |
| Brainstorm | New from Reddit (test): CoronaVirus_2019_nCoV: Broadly Neutralizing Monoclonal Antibodies For Covid-19 Treatment, Prevention, And Vaccine Design → https://old.reddit.com/r/CoronaVirus_2019_nCoV/comments/y4xc35/broadly_neutralizing_monoclonal_antibodies_for/ | 22:11 |
| Brainstorm | Updates for Canada: +1023 cases, +8 deaths since a day ago | 23:09 |
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