libera/##covid-19/ Sunday, 2022-10-23

de-factois it this XBB variant?00:01
sKep_~_00:01
de-facto"XBB is a recombinant variant – meaning that it's a combination of two other BA.2 Omicron subvariants (specifically, BA.2.10.1 + BA.2.75)."00:02
de-factohttps://www.who.int/activities/tracking-SARS-CoV-2-variants00:03
de-facto"Recombinant of BA.2.10.1 and BA.2.75 sublineages, i.e. BJ1 and BM.1.1.1, with a breakpoint in S1" with "BA.2+ S:V83A, S:Y144-, S:H146Q, S:Q183E, S:V213E, S:G252V, S:G339H, S:R346T, S:L368I, S:V445P, S:G446S, S:N460K, S:F486S, S:F490S"00:04
de-factoyeah i mean we will have to see, lots of new variants and recombinations will happen, question is which of them will dominate the others00:05
de-factosurely something immuno-evasive hence with growth advantage under the given circumstances (such as most prevalent type of immunity from vaccinations and previous waves)00:06
sKep_bloody rothchilds00:06
de-factoits not really clear which on those new variants will turn out to be the ancestor of future variants, its all a question of natural selection00:07
sKep_I am waiting for the Siberia's variant00:07
de-factowhy specifically Siberia?00:08
sKep_wait and watch00:08
de-factoarent people there living quite separated, e.g. with not a lot of traveling?00:08
de-factoid expect the next variant to come from a highly interconnected area with lots of susceptible having contacts, so areas with the most "processing power" in terms of trial and error for new mutants that can try to spread under given most common circumstances00:09
sKep_indeed00:10
de-factothe more "bruteforce" the higher the probability for finding a new variant (by natural selection)00:10
BrainstormNew from Reddit (test): nCoV: New Boston virus | 22OCT22 → https://old.reddit.com/r/nCoV/comments/yb03dd/new_boston_virus_22oct22/00:17
LjL%print https://twitter.com/yunlong_cao/status/157339124782137344001:57
BrainstormLjL, It says: Yunlong Richard Cao on Twitter: "As expected, BQ.1.1 escapes Evusheld and bebtelovimab, making all clinically available antibody drugs ineffective. BQ.1.1 and BA.2.75.2 both displayed sufficient hACE2 binding capability. (3/4) https://t.co/DTiyHsJfJP" / Twitter01:57
BrainstormUpdates for Guatemala: +687 cases, +3 deaths since a day ago02:00
BrainstormNew from ##covid-19 Zotero group: Imprinted SARS-CoV-2 humoral immunity induces convergent Omicron RBD evolution: Type Preprint Author Yunlong Cao Author Fanchong Jian Author Jing Wang Author Yuanling Yu Author Weiliang Song Author Ayijiang Yisimayi Author Jing Wang Author Ran An Author Na Zhang Author Yao Wang [... want %more?] → https://www.zotero.org/groups/covid_links/items/6MW9ZFEB02:08
BrainstormUpdates for South Korea: +26256 cases, +16 deaths since 23 hours ago03:09
BrainstormNew from r/COVID19: COVID19: Prevalence and clinical implications of persistent or exertional cardiopulmonary symptoms following SARS-CoV-2 infection in 3597 collegiate athletes: a study from the Outcomes Registry for Cardiac Conditions in Athletes (ORCCA) → https://old.reddit.com/r/COVID19/comments/yb6i33/prevalence_and_clinical_implications_of/05:15
BrainstormNew from r/COVID19: COVID19: Prevalence of Positive Rapid Antigen Tests After 7-Day Isolation Following SARS-CoV-2 Infection in College Athletes During Omicron Variant Predominance → https://old.reddit.com/r/COVID19/comments/yb6mwb/prevalence_of_positive_rapid_antigen_tests_after/05:24
BrainstormUpdates for Germany: +1 cases since a day ago06:03
BrainstormNew from This Week In Virology: TWiV 948: Breathless with David Quammen: David Quammen returns to TWiV to discuss how he wrote his new book ‘Breathless’, a story about the science and the scientists behind the race to understand the pandemic coronavirus SARS-CoV-2. → https://www.microbe.tv/twiv/twiv-948/06:12
BrainstormUpdates for Metropolitana, Chile: +2527 cases, +7 deaths since 23 hours ago — Selangor, Malaysia: +1147 cases, +1 deaths since 23 hours ago — Valparaiso, Chile: +540 cases, +4 deaths since 23 hours ago — Araucania, Chile: +402 cases, +2 deaths since 23 hours ago08:08
BrainstormNew from r/Coronavirus: Daily Discussion Thread | October 23, 2022: Please refer to our Wiki for more information on COVID-19 and our sub. You can find answers to frequently asked questions in our FAQ , where there is valuable information such as our: → https://old.reddit.com/r/Coronavirus/comments/ybaq3f/daily_discussion_thread_october_23_2022/09:10
de-factohttps://www.eurekalert.org/news-releases/96791612:23
de-facto%title12:23
Brainstormde-facto: From www.eurekalert.org: New Omicron subvariant largely evades neutral | EurekAlert!12:23
BrainstormNew from r/COVID19: COVID19: SARS-CoV-2 infected cells sprout actin-rich filopodia that facilitate viral invasion → https://old.reddit.com/r/COVID19/comments/ybcein/sarscov2_infected_cells_sprout_actinrich/12:26
BrainstormNew from PubMed: A systematic review and meta-analysis of the epidemiological characteristics of COVID-19 in children: CONCLUSIONS: The pediatric clinical picture of COVID-19 is not simply a classic respiratory infection, but unusual presentations have been reported. Given the high incidence of household transmission and atypical [... want %more?] → https://pubmed.ncbi.nlm.nih.gov/36273121/13:04
BrainstormUpdates for China: +6508 cases, +4 deaths since 22 hours ago — UAE: +312 cases since 19 hours ago13:06
BrainstormUpdates for Japan: +30873 cases, +44 deaths since 23 hours ago14:02
de-factohttps://www.cnn.com/2022/10/21/health/virginia-high-school-flu-absences-stafford-county/index.html14:24
de-facto%title14:24
Brainstormde-facto: From www.cnn.com: Stafford County, Virginia: Nearly half the students at a Virginia high school are absent with flu-like symptoms, district says | CNN14:24
de-factoHmm whats the pathogen?14:24
BrainstormNew from Reddit (test): Global COVID Cases For 23OCT22: Summary As Of: 23OCT @ 12:18 GMT Countries 228 + 2 Cases 632,787,161 Deaths 6,582,512 Recovered 611,617,944 Active Cases 14,586,705 Countries reporting new cases: 34 Countries reporting new deaths: 17 Countries reporting increased Active [... want %more?] → https://old.reddit.com/r/nCoV/comments/ybggeg/global_covid_cases_for_23oct22/14:37
BrainstormNew from r/Coronavirus: Coronavirus: A ‘Tripledemic’? Flu and Other Infections Return as Covid Cases Rise → https://old.reddit.com/r/Coronavirus/comments/ybglr8/a_tripledemic_flu_and_other_infections_return_as/14:47
BrainstormNew from r/Coronavirus: Coronavirus: Among Seniors, a Declining Interest in Boosters → https://old.reddit.com/r/Coronavirus/comments/ybh04q/among_seniors_a_declining_interest_in_boosters/15:05
BrainstormNew from r/COVID19: COVID19: Development of forecast models for COVID-19 hospital admissions using anonymized and aggregated mobile network data → https://old.reddit.com/r/COVID19/comments/ybhpui/development_of_forecast_models_for_covid19/15:33
BrainstormNew from Contagion Live: Investigational RSV Vaccine for Seniors Demonstrates Efficacy and Safety: During a late breaking session at ID Week, an investigator presented data on the GSK vaccine that is in development. → https://www.contagionlive.com/view/investigational-rsv-vaccine-for-seniors-demonstrates-efficacy-and-safety17:07
sKepde-facto: y017:25
de-facto%title https://covariants.org/variants/22E.Omicron17:35
Brainstormde-facto: From covariants.org: CoVariants: 22E (Omicron)17:35
de-facto%title https://www.biorxiv.org/content/10.1101/2022.09.15.507787v317:36
Brainstormde-facto: From www.biorxiv.org: Imprinted SARS-CoV-2 humoral immunity induces convergent Omicron RBD evolution | bioRxiv17:36
sKep%cases india17:37
BrainstormsKep: India has had 44.6 million confirmed cases (3.3% of all people) and 528961 deaths (1.2% of cases; 1 in 2572 people) as of 9 hours ago. 899.6 million tests were done (0.7 per capita, 5.0% positive). 857.8 million were vaccinated (63.1%). +836 cases, +4 deaths since 8 hours ago. See https://www.mygov.in/covid-19 or https://www.covid19india.org/17:38
BrainstormNew from Reddit (test): CoronavirusUK: Effectiveness of Monovalent mRNA Vaccines Against COVID-19–Associated Hospitalization Among Immunocompetent Adults During BA.1/BA.2 and BA.4/BA.5 Predominant Periods of SARS-CoV-2 Omicron Variant in the United States → https://old.reddit.com/r/CoronavirusUK/comments/ybljx4/effectiveness_of_monovalent_mrna_vaccines_against/18:12
sKepi dont think so covid is a terror for future18:14
sKepdrink whiskey and live your life18:14
BrainstormUpdates for Chile: +6228 cases, +14 deaths since a day ago — Italy: +25553 cases, +52 deaths, +161787 tests since a day ago19:07
BrainstormNew from r/COVID19: COVID19: Do open data impact citizens’ behavior? Assessing face mask panic buying behaviors during the Covid-19 pandemic → https://old.reddit.com/r/COVID19/comments/ybmc15/do_open_data_impact_citizens_behavior_assessing/19:27
BrainstormNew from Contagion Live: Treating Expecting Mothers with Sotrovimab for COVID-19: Late breaking data was reported utilizing the monoclonal antibody during the era of when Omicron variant was the predominant strain and demonstrated good outcomes and tolerability. → https://www.contagionlive.com/view/treating-expecting-mothers-with-sotrovimab-for-covid-1920:05
ublxI'm used to NPR being GDPR-walled but this one isn't for some reason: https://www.npr.org/2022/10/21/1130371456/remote-work-opened-some-doors-to-workers-with-disabilities-but-others-remain-shu21:33
ublx"Researchers collected online responses from supervisors working in companies with at least 15 employees from May 11 through June 25 ... Among nearly 3,800 supervisors surveyed ... Forty percent of respondents said they had supervised someone with lasting physical or mental challenges associated with COVID-19."21:33
LjL%print https://twitter.com/EricTopol/status/158424439775907840221:43
BrainstormLjL, It says: Eric Topol on Twitter: "It's not a good sign when 3 shots and a breakthrough (BA.1) infection (lower panel) doesn't elicit neutralizing antibodies to some of the new variants (BQ.1.1, XBB, BA.2.75.2)" / Twitter21:43
LjLublx, you can't see the elephant in the room if your visual cortex is damaged21:43
BrainstormNew from Reddit (test): CoronaVirus_2019_nCoV: COVID-19 chaos: Presidential efforts fail as doctors are left trapped → https://old.reddit.com/r/CoronaVirus_2019_nCoV/comments/ybqyij/covid19_chaos_presidential_efforts_fail_as/21:48
BrainstormUpdates for Canada: +582 cases, +2 deaths since 23 hours ago23:04
ulu%cases germany23:10
Brainstormulu: Germany has had 35.2 million confirmed cases (42.3% of all people) and 152482 deaths (0.4% of cases; 1 in 545 people) as of 17 hours ago. 131.3 million tests were done (1.6 per capita, 26.8% positive). 61.8 million were vaccinated (74.3%). +1 cases since a day ago. See https://corona.rki.de/23:10

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