libera/##covid-19/ Tuesday, 2022-10-25

BrainstormUpdates for South Africa: +693 cases since 3 days ago00:04
BrainstormNew from Reddit (test): CoronaVirus_2019_nCoV: Epidemic of Brain Fog? Long COVID’s Effects Worry Experts: “I'm very worried that we have an epidemic of neurologic dysfunction coming down the pike,” says Pamela Davis, MD, PhD, a research professor at Case [... want %more?] → https://old.reddit.com/r/CoronaVirus_2019_nCoV/comments/yco1db/epidemic_of_brain_fog_long_covids_effects_worry/00:08
BrainstormNew from The Lancet (Online): [Viewpoint] After 2 years of the COVID-19 pandemic, translating One Health into action is urgent: The world is coping with the health, societal, and economic consequences of more than 2 years of the COVID-19 pandemic. Emerging diseases caused by new pathogens, [... want %more?] → https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(22)01840-2/fulltext00:37
LjLI read this thread, and it positively made me dumber. I'm just one person but n=1 is a valuable sample, duh https://twitter.com/mildanalyst/status/158459658518253158401:17
BrainstormNew from r/COVID19: COVID19: Antibody responses to Omicron BA.4/BA.5 bivalent mRNA vaccine booster shot → https://old.reddit.com/r/COVID19/comments/ycp6kv/antibody_responses_to_omicron_ba4ba5_bivalent/01:43
LjLAt ~3-5 weeks post booster shot, individuals who received a fourth vaccine dose with a bivalent mRNA vaccine targeting BA.4/BA.5 had similar neutralizing antibody titers as those receiving a fourth monovalent mRNA vaccine against all SARS-CoV-2 variants tested, including BA.4/BA.5. Those who received a fourth monovalent vaccine dose had a slightly higher neutralizing antibody titers than those who received the bivalent vaccine against three related sarbecoviruses:01:49
LjLSARS-CoV, GD-Pangolin, and WIV1. When given as a fourth dose, a bivalent mRNA vaccine targeting Omicron BA.4/BA.5 and an ancestral SARS-CoV-2 strain did not induce superior neutralizing antibody responses in humans, at the time period tested, compared to the original monovalent vaccine formulation.01:49
LjL↑ de-facto01:49
LjL>:01:49
* LjL mad01:49
LjLthis is worse than the BA.1 booster01:49
LjLthe hell i'm taking a "oh don't worry all our vaccines are tested equally" vaccine next time01:50
LjL(words from the uninformed nurse/doctor who gave me the fourth shot when i inquired about its lack of human trialling)01:50
xxwhy would a nurse/doctor know the specifics about the vaccine they are administering?01:51
xxit's not on the leaflet01:51
xxthis is the sort of stuff one has to specifically look up01:51
LjLwell, there was nothing to look up until now01:55
LjLthere were no public data to be found about the BA.4/5 booster01:56
xxthat doesn't stop the nurse/doctor from making something up to appease a patient that looks uneasy01:57
xxthey are permitted to lie01:57
LjLso much for no original antigenic sin, also02:01
LjL"All cohorts exhibited the highest serum virus-neutralization titers6602:01
LjL(ID50 ) against the ancestral D614G strain (Figure 1A)."02:01
LjLso it works LESS well on the original strain and NOT ANY BETTER on the strain it's targeted for02:01
LjLworst news of the... month?02:01
LjL"These findings may be indicative of7702:02
LjLimmunological imprinting5, although follow-up studies are needed to determine if the antibody7802:02
LjLresponses will deviate in time, including the impact of a second bivalent booster."02:02
BrainstormUpdates for Bulgaria: +1145 cases, +19 deaths since 21 hours ago — Bahrain: +453 cases, +4305 tests since a day ago02:08
BrainstormNew from ##covid-19 Zotero group: Antibody responses to Omicron BA.4/BA.5 bivalent mRNA vaccine booster shot: Type Preprint Author Qian Wang Author Anthony Bowen Author Riccardo Valdez Author Carmen Gherasim Author Aubree Gordon Author Liu Lihong Author David D. Ho URL [... want %more?] → https://www.zotero.org/groups/covid_links/items/QC3XL7YD02:12
de-factoLjL did you look at the graphs at the last page of tgat PDF?02:21
de-factoImho the bivalent looks equivalent or maybe even a tiny but better for some newer variants, though not really significantly02:23
LjLde-facto, yes, i did02:28
LjLimo it doesn't look even remotely statistically significantly better02:28
LjLTopol is already on it too02:29
LjL%print https://twitter.com/EricTopol/status/158464741965211648102:29
BrainstormLjL, It says: Eric Topol on Twitter: "New on the bivalent BA.5 vaccine booster immune response in people No better neutralizing antibody response to BA.5 than the original vaccine (WT) https://t.co/QT5emKLFXz https://t.co/GKiknxFnT2" / Twitter02:29
LjL%print https://twitter.com/EricTopol/status/158465063870493491202:29
BrainstormLjL, It says: Eric Topol on Twitter: ""The findings may be indicative of immunological imprinting" Bottom line: Until more data are available, regard the bivalent booster as equivalent to a booster which augments and broadens immunity, without specific anti-BA.5 properties." / Twitter02:29
LjLoriginal antigenic sin is BAD news02:29
LjLfor any future boosters02:29
LjLI like how they've all changed the terminology from "original antigenic sin" (which they had dismissed" to "immunological imprinting", so it doesn't sound like it's the same thing02:30
LjLbleh02:30
de-factoDid they write about the time fir forth dose after third?02:30
de-factoThe shorter that contraction time the more sin id guesd02:33
de-factoAlso "Individuals who received four monovalent mRNA doses were older (mean age 55.3) than those 63 who received a bivalent booster (mean age 36.4)"02:40
LjLde-facto, because older people were prioritized for a booster but the variant-specific one wasn't there yet02:53
LjLsame as what happened to my parents02:53
LjLso you can probably assume that the people who got the bivalent waited more02:53
de-factohmm not sure, id assume their whole shedule is delayed02:55
de-factoYet sera were taken with similar delay02:55
de-factoso only difference is mean age, yet i wonder about contraction time02:56
de-factoextremes would be few weeks after 3rd to boost with 4th, that probably would just increase level without changing spectrum of antigenic breath, compared to lets say almost a year contraction time02:59
de-factoQuestion being if long contraction time would allow for more plasticity of the immune response in terms of ability to change the antigenic spectrum according to the novelty in the bivalent shots03:01
de-factoWould that not be the way one could expect the immune system to have evolved with natural selection under natural speed for antigenic drift of a pathogen in circulation of a population?03:05
LjLsorry i'm not following, i'm just very disappointed and disheartened now03:07
de-factoIf exposure times happen with short delay the estimated antigenic drift would not nearly be as far as for a longer delay between exposure times03:08
de-factoHence in the former case the immune response most likely would be successful without much plasticity, so neutralizing with almost the same spectrum03:09
BrainstormUpdates for Norway: +126 cases since 23 hours ago — Canada: +608 cases, +4 deaths since 8 hours ago03:10
de-factoIn the long delay case though, with long contraction time, the immune response would have to adapt to the large antigenic drift that the pathogen most likely did achieve in that long delay time since last seen by the immune system03:12
de-factowhat do you think about that conjecture LjL?03:12
LjLas i said i'd rather withdraw from the conversation for now as i'm depleted03:13
de-factoI think contraction time is relevant for imprinting due to the points above03:18
de-factoMaybe ideal contraction time could be a year due to seasonality of many respiratory pathogen, who knows03:35
BrainstormNew from r/Science: science: People who reported experiencing side effects to the Pfizer/BioNTech and Moderna Covid-19 vaccines such as fever, chills or muscle pain tended to have a greater antibody response following vaccination → https://old.reddit.com/r/science/comments/ycsuby/people_who_reported_experiencing_side_effects_to/04:24
BrainstormUpdates for Germany: +115534 cases, +273 deaths since a day ago — South Korea: +43714 cases, +17 deaths since a day ago — New Zealand: +16343 cases since 20 hours ago05:02
BrainstormUpdates for Portugal: +7637 cases, +75 deaths since 6 days ago07:01
BrainstormUpdates for North Rhine-Westphalia, Germany: +29932 cases, +50 deaths since 2 days ago — New York, United States: +6642 cases, +34 deaths since a day ago — Schleswig-Holstein, Germany: +4272 cases, +7 deaths since 2 days ago — New Jersey, United States: +4101 cases, +2 deaths since a day ago08:03
BrainstormNew from r/Coronavirus: Daily Discussion Thread | October 25, 2022: Please refer to our Wiki for more information on COVID-19 and our sub. You can find answers to frequently asked questions in our FAQ , where there is valuable information such as our: → https://old.reddit.com/r/Coronavirus/comments/ycy9y7/daily_discussion_thread_october_25_2022/09:03
BrainstormNew from r/COVID19: COVID19: Prone positioning, a simple technique of turning people from the back onto the stomach, can help beat respiratory distress. → https://old.reddit.com/r/COVID19/comments/ycycc4/prone_positioning_a_simple_technique_of_turning/09:12
BrainstormUpdates for Taiwan: +39152 cases, +42 deaths, +58556 tests since 23 hours ago10:08
BrainstormNew from StatNews: Opinion: Covid-19 is an inverse equity story, not a racial equity success story: It is worth celebrating the tenacity of community champions who fought for equitable access to vaccines by Black and Hispanic people. But fixing injustice requires fundamental [... want %more?] → https://www.statnews.com/2022/10/25/covid-19-inverse-equity-story-not-racial-equity-success-story/10:47
BrainstormNew from StatNews: Got questions about the timing of flu and Covid vaccines? Here’s what experts say: With the third Covid winter approaching amid an early flu season, experts agree that the best time to get vaccinated is now, before these viral ripples [... want %more?] → https://www.statnews.com/2022/10/25/got-questions-about-the-timing-of-flu-and-covid-vaccines-heres-what-experts-say/10:57
BrainstormUpdates for Lithuania: +824 cases, +5 deaths since 17 hours ago11:04
BrainstormNew from NPR Science: Omicron keeps finding new evolutionary tricks to outsmart our immunity: SARS-CoV-2 is evolving "rapidly," spawning one new variant after another. But omicron continues to dominate, raising new questions about how evolution of the virus is headed. → https://www.npr.org/sections/health-shots/2022/10/25/1129196088/covid-new-omicron-variants-immunity11:07
BrainstormNew from ProPublica: Greg Abbott’s Executive Power Play: by Perla Trevizo and Marilyn W. Thompson ProPublica is a nonprofit newsroom that investigates abuses of power. Sign up to receive our biggest stories as soon as they’re published. This article is co-published with The Texas Tribune, a nonprofit, [... want %more?] → https://www.propublica.org/article/greg-abbotts-executive-power-play12:43
BrainstormNew from PubMed: Performance Comparison Between Fourier-Transform Infrared Spectroscopy-based IR Biotyper and Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry for Strain Diversity: CONCLUSIONS: IR Biotyper is useful for diversity analysis with improved discriminatory power over MALDI-TOF MS in comparison [... want %more?] → https://pubmed.ncbi.nlm.nih.gov/36281511/13:02
BrainstormUpdates for Japan: +47706 cases, +38 deaths since 23 hours ago — China: +6310 cases, +10 deaths since 23 hours ago — Slovenia: +2108 cases since 23 hours ago13:08
BrainstormNew from r/Science: science: Merck pays Moderna $250m for personalized cancer vaccine → https://old.reddit.com/r/science/comments/yd18ln/merck_pays_moderna_250m_for_personalized_cancer/13:31
BrainstormUpdates for Indonesia: +3008 cases, +21 deaths, +69498 tests since a day ago14:10
BrainstormNew from r/Science: science: Regular physical activity may boost effectiveness of COVID-19 jab. Risk of hospital admission among fully vaccinated healthcare workers was reduced by 60% in the group who engaged in low levels of physical activity, and by 72% and 86% in the [... want %more?] → https://old.reddit.com/r/science/comments/yd1rf9/regular_physical_activity_may_boost_effectiveness/14:18
BrainstormNew from Reddit (test): nCoV: Global COVID Cases For 25OCT22 → https://old.reddit.com/r/nCoV/comments/yd3j5u/global_covid_cases_for_25oct22/14:28
BrainstormUpdates for Romania: +692 cases, +3 deaths since 21 hours ago — Malta: +28 cases since 23 hours ago15:00
BrainstormNew from r/COVID19: COVID19: Imprinted antibody responses against SARS-CoV-2 Omicron sublineages → https://old.reddit.com/r/COVID19/comments/yd3xow/imprinted_antibody_responses_against_sarscov2/15:07
BrainstormNew from Il Sole 24 Ore: (translated) Goodbye to the Covid bulletin, split experts: away immediately, no remains for transparency: Among the first measures that the new Minister of Health Orazio Schillaci should take on Covid is to modify the bulletin that [... want %more?] → https://www.ilsole24ore.com/art/addio-bollettino-covid-esperti-spaccati-via-subito-no-resti-trasparenza-AEzUdUBC15:36
LjL:(15:44
LjLsure, let's do like the UK, they're smart15:46
ublxhey i just had bivalent moderna half an hour ago and the administering nurse had heard of bq.1!15:52
ublxshe hadn't heard of the results you foregrounded last night, though15:53
BrainstormNew from ##covid-19 Zotero group: (translated) Goodbye to the Covid bulletin? split experts: away immediately, no remains for transparency: Type Web Page Author Marzio Bartoloni URL https://www.ilsole24ore.com/art/addio-bollettino-covid-esperti-spaccati-via-subito-no-reste-trasparenza-AEzUdUBC Date 2022-10-25T13: 29: [... want %more?] → https://www.zotero.org/groups/covid_links/items/CLR88YFE15:56
LjLublx, BA.1 or BA.515:57
LjLi was pretty pissed last night15:58
LjLand frustrated for other reasons. couldn't sleep well.15:58
ublxmoderna bivalent spikevax (UK licenced), the BA component of which (according to this pamphlet) is directed at BA.1.1.52916:04
LjLO.o16:07
LjLspecific16:07
LjLanyway, probably better off than with BA.5 apparently16:07
ublxyay for NHS using up old stock?16:07
LjLwhat does that teach us about using vaccines not tested on humans AND not even really tested on mice seriously?16:07
BrainstormUpdates for Hong Kong: +5221 cases, +10 deaths since a day ago16:08
ublxfrom: https://www.gov.uk/government/news/first-bivalent-covid-19-booster-vaccine-approved-by-uk-medicines-regulator16:11
ublx"The MHRA’s decision (granting licence approval) is based on data from a clinical trial which showed that a  booster with the  bivalent  Moderna vaccine triggers a strong immune response against both Omicron (BA.1) and the original 2020 strain. In an exploratory analysis the bivalent vaccine was also found to generate a good immune response against the Omicron sub-variants BA.4 and BA.5."16:11
LjLyeah, i don't even... it works better on BA.4/5 than the thing made for it16:12
ublxwonder if that page's maintainers read biorxiv posts16:12
LjLi kinda just hope that study was all flawed and they'll say naaaah we were wrong nevermind it works fine16:12
LjLbut anyway, next vaccine, i want something we know ANYTHING about16:13
LjLeven just antibody levels, but AT LEAST THAT16:13
ublxwell16:19
ublxrecency of vaccine seems like a big deal, apart from individual vaccine performance16:21
ublxfrom: https://erictopol.substack.com/p/a-booster-is-your-best-shot-now16:21
ublxhttps://substackcdn.com/image/fetch/w_1456,c_limit,f_webp,q_auto:good,fl_progressive:steep/https%3A%2F%2Fbucketeer-e05bbc84-baa3-437e-9518-adb32be77984.s3.amazonaws.com%2Fpublic%2Fimages%2Fe4dab4c1-d9bb-42eb-ab9b-0bdaf87a1e1a_2446x1866.jpeg16:21
LjLsure16:23
LjLbut then whatever, i could have gotten the BA.116:23
LjLi thought i was trading "unknown effects on humans" with "most likely better action against BA.5"16:23
LjLinstead i just got injected something only tested on mice, and turns out, it sucks16:23
LjLgood fucking idea, not16:23
ublxsure iirc from last night it went about the same for BA5 and not great for ancestral strains16:24
ublxbut how high are the odds of encountering older strains16:25
ublxbeing as each new strain seems to achieve its foothold by out competing its predecessor16:26
ublxso idk, being preprint and early attempt at analysis, handwave to ~ about the same16:27
BrainstormNew from Reddit (test): nCoV: The SARS-CoV-2 spike protein subunit S1 induces COVID-19-like acute lung injury in Κ18-hACE2 transgenic mice and barrier dysfunction in human endothelial cells | 21APR22 → https://old.reddit.com/r/nCoV/comments/yd6vwk/the_sarscov2_spike_protein_subunit_s1_induces/17:04
-Bridgestorm- 🌑 Lindol! Earthquake! 5.9 Mb tremor, registered by GEOFON,alomax, with 120 reports, 20 early, occurred 11 minutes ago (14:59:02 UTC), during a new moon night, Luzon, Philippines (17.41, 120.89) ± 67 km, ↓11 km likely felt 330 km away by 100 people (Twitter)17:10
BrainstormUpdates for Montenegro: +89 cases, +895 tests since a day ago17:11
BrainstormNew from Reddit (test): nCoV: COVID-19 and the surge in Decidual Cast Shedding | 21APR22 → https://old.reddit.com/r/nCoV/comments/yd71g2/covid19_and_the_surge_in_decidual_cast_shedding/17:13
-Bridgestorm- ⭕ Lindol! Earthquake! 6.5 Mww tremor, registered by PT, occurred 23 minutes ago (14:59:01 UTC), during a new moon night, San Juan, Philippines (17.69, 120.81), ↓15 km likely felt 380 km away (in Bangued, La Paz, Lagangilang, San Juan, Dolores, Bucay…) by 1.7 million people (service.iris.edu)17:22
BrainstormNew from EMA: Human medicine assessment reports: (news): Human medicines European public assessment report (EPAR): RoActemra, tocilizumab, Arthritis, Rheumatoid;Arthritis, Juvenile Rheumatoid;Cytokine Release Syndrome;Giant Cell Arteritis;COVID-19 virus infection, Date of authorisation: 15/01/2009, Revision: 40, [... want %more?] → https://www.ema.europa.eu/en/medicines/human/EPAR/roactemra17:51
LjL-Matrixublx: yeah you're right ultimately it's going to be about as good as any other, except it wasn't even tested on people, so if I grow a third hand... But no really side effects are not very likely, I'm just angry at how the whole thing was done pretty much ultimately as a cash cow for Pfizer without being useful, and very bad practices such as utter lack of even a bare minimum of human trial. Safety takes time to assess but antibodies would18:05
LjL-Matrixhave been easy. But no, first jab me, then tell me it's no good18:05
LjL-MatrixHad I had this information I'd have gotten the BA.1, also considering dome BA.1 subvariants are now rearing their ugly heads18:06
LjL-MatrixPlus, ultimately, we can't keep being jabbed every four months, even worse if variant specific stuff doesn't work because of antigenic sin, and meanwhile this study that says (not without ample criticism) that risks get exponentially worse with each reinfection18:07
LjL-MatrixI just wasn't very happy to learn all this18:07
LjL-MatrixI think this virus has given me enough bad news, and it could show the decency of stopping18:08
LjL-MatrixBut then again, that's me being arrogant and self centered as usual because I didn't get it, my immediate family didn't get it except my sister who seems fine, and I live a life (sigh) that makes getting it not very likely18:08
LjL-MatrixCompare: my Alps friend whose 62 year old dad died of it while in the Alps, in one of the worst provinces in 2020 back when you couldn't see your dying or dead relatives at all18:09
BrainstormNew from r/Coronavirus: Coronavirus: A Virginia high school will stay open while hundreds of students call out sick with flu-like symptoms → https://old.reddit.com/r/Coronavirus/comments/yd8425/a_virginia_high_school_will_stay_open_while/18:20
xxstop animal testing, start consentual paid human testing instead18:21
LjL-MatrixAnimal testing that's most useful (in general, vaccines aside) is the type where you eventually open up the animal and see what their tissues are like, which you can't do with humans except in autopsies which have serious limitations18:22
xxit's possible to do with humans too, if the pay is good for example18:24
xxalternatively, at the very least it would prompt research into alternative methods of obtaining results that don't require invasive stuff like that18:25
BrainstormUpdates for Italy: +48713 cases, +120 deaths, +297268 tests since 23 hours ago19:03
BrainstormNew from Contagion Live: “It’s Potentially Game-Changing”: Hepatitis B Vaccination Protects People Living With HIV: A late-breaking IDWeek 2022 study found high seroprotection was achieved among people living with HIV after receiving 3 doses of a [... want %more?] → https://www.contagionlive.com/view/-it-s-potentially-game-changing-hepatitis-b-vaccination-protects-people-living-with-hiv19:07
LjL<xx> it's possible to do with humans too, if the pay is good for example ← i'm late so i won't, but that's a kick or a temporary ban next time. just no.19:41
xxhmm? Paid medical testing is a thing already19:42
LjLnot being cut open and presumably dead19:42
LjLwhen you weren't otherwise going to die19:42
LjLit definitely isn't19:42
xxtissue samples are taken as part of many clinical trials19:42
xxe.g. lung tissue biopsies (from live subjects) was done as part of covid trials19:43
LjLthat's different from what i said is being done with animals19:43
LjLit's objectively easier to find things if you have a dead body that you can just cut open and check around19:44
xxthen I misunderstood what you wrote19:44
LjLjust doing that with humans *if that entails killing them* is way off limits19:44
xxyeah that wasn't clear from what you wrote19:44
BrainstormNew from r/COVID19: COVID19: Evaluating and mitigating the potential indirect effect of COVID-19 on control programmes for seven neglected tropical diseases: a modelling study → https://old.reddit.com/r/COVID19/comments/ydb16e/evaluating_and_mitigating_the_potential_indirect/20:26
BrainstormNew from Reddit (test): CoronaVirus_2019_nCoV: Got COVID? Your symptoms may depend on your vaccination status: "I don't think it's really possible, from patients' initial symptoms, to distinguish COVID from what we long called 'influenza-like illnesses.'" That means [... want %more?] → https://old.reddit.com/r/CoronaVirus_2019_nCoV/comments/ydc1h1/got_covid_your_symptoms_may_depend_on_your/20:35
BrainstormNew from Reddit (test): CoronaVirus_2019_nCoV: Some coronaviruses kill, while others cause a common cold. We are getting closer to knowing why → https://old.reddit.com/r/CoronaVirus_2019_nCoV/comments/ydccgj/some_coronaviruses_kill_while_others_cause_a/20:45
BrainstormNew from CIDRAP: COVID-19 Scan for Oct 25, 2022: Urban vs rural COVID deaths Physical activity and COVID vaccine → https://www.cidrap.umn.edu/news-perspective/2022/10/covid-19-scan-oct-25-202221:04
BrainstormNew from CIDRAP: COVID hospital patients at higher risk of cardiac events, data suggest: Mary Van Beusekom | News Writer | CIDRAP News Oct 25, 2022 COVID patients discharged from the hospital were at about 21 times the risk of heart failure and 17 times the [... want %more?] → https://www.cidrap.umn.edu/news-perspective/2022/10/covid-hospital-patients-higher-risk-cardiac-events-data-suggest21:14
BrainstormNew from CIDRAP: White House announces more steps to battle fall COVID-19 activity: Lisa Schnirring | News Editor | CIDRAP News Oct 25, 2022 "If we really want to put COVID behind us, we have to keep the fight together," President Biden says. → https://www.cidrap.umn.edu/news-perspective/2022/10/white-house-announces-more-steps-battle-fall-covid-19-activity21:42
BrainstormNew from Johnson&Johnson: Innovation: U.S. FDA Approves TECVAYLI  (teclistamab-cqyv), the First Bispecific T-cell Engager Antibody for the Treatment of Patients with Relapsed or Refractory [... want %more?] → https://www.jnj.com/u-s-fda-approves-tecvayli-teclistamab-cqyv-the-first-bispecific-t-cell-engager-antibody-for-the-treatment-of-patients-with-relapsed-or-refractory-multiple-myeloma22:02
BrainstormUpdates for Albania: +40 cases since 21 hours ago — Morocco: +35 cases, +1 deaths since a day ago — Sri Lanka: +12 cases since a day ago22:09
BrainstormUpdates for Serbia: +1215 cases, +6 deaths, +13174 tests since 23 hours ago22:59
BrainstormNew from WebMD: Is It Flu, RSV or COVID? Experts Fear the ‘Tripledemic’: Will cases of RSV, COVID-19, and influenza rise together? Public health officials urge precautions, while noting that the flu and RSV viruses are simply playing catchup after lockdowns and social distancing. → https://www.webmd.com/cold-and-flu/news/20221025/is-it-flu-rsv-or-covid-experts-fear-the-tripledemic23:18

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