| Brainstorm | Updates for Germany: +46 deaths since 23 hours ago | 00:01 |
|---|---|---|
| LjL | Vietnam, Korea etc are scary | 00:01 |
| LjL | %cases Vietnam | 00:01 |
| Brainstorm | LjL: Vietnam has had 4.4 million confirmed cases (4.6% of all people) and 40813 deaths (0.9% of cases; 1 in 2357 people) as of 56 minutes ago. 80.1 million tests were done (0.8 per capita, 5.5% positive). 77.9 million were vaccinated (80.9%). +202180 cases, +87 deaths, +261466 tests since a day ago. See https://offloop.net/covid19/?default=Vietnam&legacy=no | 00:01 |
| Brainstorm | New from r/COVID19: COVID19: The neuroinvasiveness, neurotropism, and neurovirulence of SARS-CoV-2 → https://old.reddit.com/r/COVID19/comments/t8asrz/the_neuroinvasiveness_neurotropism_and/ | 00:02 |
| Tuvix | My understanding for some of the drivers there is the older population is highly vulnerable due to poor vaccination in that age-group in particular. | 00:09 |
| Tuvix | The US has seen similar results of the 65+ population driving a large part of the deaths, although that also hides some rather interesting sub-analysis on the younger ages during waves where there can be "less death" overall, but harder-hit younger age groups, such as Delta taking more lives at its peak while the older groups saw improvement (vs. Alpha) | 00:11 |
| Tuvix | This also points out why it's so crucial not just to vaccinate, but ensure the at-risk are getting accurate messaging and healthcare support to get information to them on the facts. | 00:11 |
| Brainstorm | Updates for Hong Kong: +31008 cases, +233 deaths since a day ago — Cook Is.: +15 cases, +192 tests (7.8% positive) since 23 hours ago | 01:04 |
| Brainstorm | New from r/COVID19: COVID19: Treatment with Ivermectin Is Associated with Decreased Mortality in COVID-19 Patients: Analysis of a National Federated Database → https://old.reddit.com/r/COVID19/comments/t8d886/treatment_with_ivermectin_is_associated_with/ | 02:03 |
| Tuvix | Yet another nonsense report that isn't blinded or placebo-controlled by a poster with a history of utter crap and intentionally inflamatory remarks. The study also seems to intentionally not control for severity of disease. | 02:16 |
| Tuvix | Really bad "study" since they're comparing people who had to meet an already high bar to be qualified to receive and then have enough supply of remdesivir to a larger population, so it's not just a bogus study, but seems to be outright dishonest and short on any real details of the math involved. (and a repost of an earlierl post about it.) | 02:18 |
| Tuvix | SOmoene | 02:18 |
| Tuvix | Erm, someone must really want to sell more of the snake oil. | 02:18 |
| Tuvix | "Further double-blinded placebo-controlled RCTs with large samples are required for definite conclusions." <- yup, no shit. | 02:18 |
| Tuvix | To translate, that says "We waved our hands and with enough cherry-picking of data we reached a conclusion which is not only suprising, but we admit is almost surely wrong but we'll publish it anyway!" | 02:19 |
| xx | I don't get why they don't just let everyone who wants have ivermectin | 02:25 |
| xx | is so cheap and would shut them up | 02:25 |
| Tuvix | You honestly don't get that? You've hung out here enough to user your head a bit more than that I'd have figured. | 02:27 |
| Tuvix | 1. Doctors don't perscribe drugs with side-effects that don't actually work. | 02:27 |
| Tuvix | 2. Supply is needed against diseases that this drug *actually* works for. | 02:27 |
| Tuvix | 3. This would be a so-called "off-label" use, which has significant legal and ethical challenges, which have already been discussed at-length elsewhere I'd strongly encourage you to look up since you are, in your own words, not getting why this framework exists today. | 02:29 |
| xx | ivermectin has no real side effects, it's one of the most well known drugs tested on literal tens of millions of people in africa. I'd use it just to shut someone up. | 02:32 |
| xx | doctors already use aspirin and paracetamol the same way, just to shut up a patient | 02:32 |
| xx | and both of those drugs have more dangerous side effects than ivermectin | 02:32 |
| Tuvix | A perscription and guidance around OTC use are very different. | 02:33 |
| xx | and yeah, I'd be perfectly fine giving ivermectin to say 1M corona patients and then pointing out "See? It does nothing. Now shut up." | 02:33 |
| xx | we could have had peace for 2 years | 02:33 |
| Tuvix | That's not how this would work, since the same people who you're trying to show it doesn't work already have the evidence it doesn't work and refuse to believe it. | 02:34 |
| Tuvix | They won't bleieve it if "you" gave them the drug and "showed" them it doesn't work. Everyone who doesn't die now points to it having saved them. Same way religion works. "I prayed to my diety and I was saved; religion works!" | 02:34 |
| Tuvix | Now, I have nothing against religion, but that logic is not scientifically sound at all. | 02:34 |
| LjL | xx, we were arguing against some guy here who was claiming ivermectin worked (though without naming it) because his two family members only had a mild case of COVID after using it prophylactically | 02:35 |
| LjL | if you are dealing with people who think THAT's proof of efficacy | 02:35 |
| LjL | it really doesn't matter how many millions of people you shove it into | 02:35 |
| LjL | they'll just believe what they want anyway | 02:35 |
| xx | shove it into everyone, eradicate human parasites, I see that as a win | 02:36 |
| LjL | i see what you did there with "human parasites" | 02:36 |
| xx | heh I see that now | 02:36 |
| Brainstorm | New from r/Science: science: Genetic study reveals causal link between blood type and COVID severity → https://old.reddit.com/r/science/comments/t8dkz2/genetic_study_reveals_causal_link_between_blood/ | 02:51 |
| LjL | again? | 02:52 |
| LjL | wasn't the link debunked in the first place? | 02:52 |
| Brainstorm | New from COVID on Twitter: Eric Topol (@EricTopol): "The pandemic isn’t over, but that doesn’t mean it should stop all of us from living—especially those who have done the most important thing to protect themselves and others."— @Craig_A_Spencer @TheAtlantic theatlantic.com/ideas/archive/… → https://twitter.com/EricTopol/status/1500657280492052485 | 03:29 |
| Brainstorm | New from r/COVID19: COVID19: A Randomized Trial of Sitagliptin and Spironolactone With Combination Therapy in Hospitalized Adults With COVID-19 → https://old.reddit.com/r/COVID19/comments/t8f3xl/a_randomized_trial_of_sitagliptin_and/ | 03:48 |
| Brainstorm | Updates for New Zealand: +17550 cases, +4752 tests (369.3% positive) since 23 hours ago | 04:04 |
| Brainstorm | New from COVID on Twitter: Spencer Cox (@SpencerJCox): Utah has the 3rd lowest rate of death from Covid. When adjusted for age we have the 7th lowest rate. bioinformaticscro.com/blog/states-ra… twitter.com/jbarro/status/… → https://twitter.com/SpencerJCox/status/1500683726920962051 | 05:14 |
| Brainstorm | Updates for Germany: +64634 cases since 16 hours ago | 06:09 |
| Brainstorm | New from r/Coronavirus: Coronavirus: ‘People were okay with leaving us behind’: COVID harder on those with disabilities, experts say → https://old.reddit.com/r/Coronavirus/comments/t8gyoz/people_were_okay_with_leaving_us_behind_covid/ | 06:20 |
| Brainstorm | New from COVID on Twitter: Scott Gottlieb, MD (@ScottGottliebMD): The average number of people per 100,000 Americans that are being newly admitted to a hospital with Covid-19 each day, at 2.5, is at the lowest level since last July, driven by far fewer relative admissions among younger age groups. Data @nytimes [... want %more?] → https://twitter.com/ScottGottliebMD/status/1500703942958845957 | 06:30 |
| Brainstorm | Updates for Sverdlovsk, Russia: +4776 cases, +8 deaths since 23 hours ago — Western Australia, Australia: +4568 cases, +1 deaths since a day ago — Bashkortostan, Russia: +3198 cases, +17 deaths since 23 hours ago — Saratov, Russia: +2574 cases, +7 deaths since 23 hours ago | 06:59 |
| minth | I think people have a strong "personal experience bias" by default | 07:29 |
| minth | they have no reason to trust information given to them by others and no way to evaluate how reliable such information is | 07:31 |
| ublx | the power of such a bias might shift in proportion to the degree of trust that exists in the community/society in question. is trust as a culture disappearing from the world? | 07:36 |
| minth | I don't think so, but some very powerful people actively undermine it | 07:42 |
| minth | CIA, FSB, WHO ... | 07:43 |
| minth | 07:43 | |
| Brainstorm | New from Science-Based Medicine: It rises again! Bleach as an “early treatment” alternative to vaccines and a cure for COVID-19: Bleach...it had to be...bleach. Again. This time around, it's being used to treat COVID-19, because of course it is. [... want %more?] → https://sciencebasedmedicine.org/it-rises-again-bleach-as-an-early-treatment-alternative-to-vaccines-and-a-cure-for-covid-19/ | 09:01 |
| Brainstorm | New from r/COVID19: COVID19: City wide observational study in Brazil using Ivermectin as a prophylactic shows a 70% reduction in mortality rates (Campbell video in comments). "It's almost as though they are willingly withholding information" → https://old.reddit.com/r/COVID19/comments/t8kko8/city_wide_observational_study_in_brazil_using/ | 09:30 |
| Brainstorm | New from r/COVID19: COVID19: Post-Acute Sequelae and Adaptive Immune Responses in People Living With HIV Recovering From SARS-Cov-2 Infection → https://old.reddit.com/r/COVID19/comments/t8l00k/postacute_sequelae_and_adaptive_immune_responses/ | 09:59 |
| Brainstorm | New from EMA: Human medicine assessment reports: (news): Human medicines European public assessment report (EPAR): Spikevax (previously COVID-19 Vaccine Moderna), elasomeran,COVID-19 mRNA vaccine (nucleoside-modified), COVID-19 virus infection, Date of authorisation: 06/01/2021, Revision: 19, Status: Authorised → https://www.ema.europa.eu/en/medicines/human/EPAR/spikevax | 10:27 |
| Brainstorm | New from StatNews: Doctors, companies push to keep looser, pandemic-era rules for prescribing opioid addiction treatment via telemedicine: It got a lot easier for patients with opioid addiction to get their medication [... want %more?] → https://www.statnews.com/2022/03/07/doctors-companies-push-to-keep-looser-pandemic-era-rules-for-prescribing-opioid-addiction-treatment-via-telemedicine/ | 10:57 |
| Brainstorm | New from StatNews: Public health experts sketch a roadmap to get from the Covid pandemic to the ‘next normal’: A new report charts a path for the transition out of the pandemic, one that outlines both how the country can deal with the challenge of endemic Covid and how… → https://www.statnews.com/2022/03/07/experts-sketch-roadmap-to-get-from-covid-pandemic-to-next-normal/ | 11:07 |
| Brainstorm | New from r/Coronavirus: Coronavirus: Lithuania cancels decision to donate Covid-19 vaccines to Bangladesh after the country abstained from UN vote on Russia → https://old.reddit.com/r/Coronavirus/comments/t8m3fz/lithuania_cancels_decision_to_donate_covid19/ | 12:07 |
| xx | ^ wtf | 12:08 |
| zutt | not very surprising | 12:10 |
| xx | why can't pro-ukraine countries accept that some countries just want to stay away from all this and remain neutral? | 12:15 |
| xx | and punish *all* humans by withholding vaccines | 12:15 |
| xx | thus making new variants of concern more likely | 12:15 |
| ublx | i read that one of (estonia|latvia|lithuania) had a pronounced right wingism problem while the other two did not, but i neglected to write down which one it was | 12:16 |
| ublx | i'm regretting not making note of that now | 12:17 |
| xx | I just treat all 3 as 1 | 12:17 |
| zutt | xx: being neutral is being pro-russian in current world politics | 12:17 |
| xx | zutt: and I am not happy about that | 12:17 |
| xx | polarizing society, giving only 2 options, never leads to anything good | 12:18 |
| xx | especially not to remaining calm, not letting emotions dictate actions, and assessing things objectively | 12:18 |
| zutt | :) | 12:18 |
| ecks | i guess they will donate the vaccines somewhere else instead | 12:19 |
| xx | same with vaccines, everyone was either blindly pro or blindly against, and no actual discussion was possible | 12:19 |
| zutt | you can tell that to the almost million Ukrainians who have had to flee their country, and the hundreds casualties from the russian bombings | 12:19 |
| zutt | and the civilians who got shot at during the two ceasefires in the last 2 days | 12:20 |
| xx | what about the civilians who now don't get the shot in bangladesh? | 12:20 |
| xx | bangladesh has nothing to do with this conflict, and doesn't want to have anything to do with it, and must be punished for that by withholding lifesaving medicine? | 12:21 |
| zutt | it's unfortunate that they don't get support from a western country that is next door to the modern day cold war areas.. | 12:23 |
| ublx | that sentiment would seem possibly to be germane if the opportunity cost of donating the vaccines were not near zero | 12:34 |
| zutt | yeah | 12:36 |
| zutt | lithuania is taking over 30k refugees (number might be outdated), it's not going to be cheap | 12:36 |
| ublx | hmm. "On 7 January 2022 44.9% of the adult Ukrainians had undergone a full course of vaccination." | 12:39 |
| ublx | opportunity cost not so near zero | 12:39 |
| zutt | thats surprisingly low number | 12:40 |
| xx | not really, lots did not want sputnik because it's russian and lots did not want the others because they were "american" | 12:42 |
| zutt | would make sense yeah, and since they don't belong to EU, they haven't been able to snatch up as many doses of the German vaccine yet | 12:43 |
| zutt | bangladesh has had over 213 million vaccinations (according to WHO) | 12:43 |
| zutt | so they have much higher coverage than Ukraine currently | 12:43 |
| ublx | about the same, possibly | 12:45 |
| ublx | population of bangladesh - 161 million | 12:45 |
| ublx | 213/3 = 71 million full courses, ~44% of population | 12:46 |
| zutt | 2 doses is a full course | 12:46 |
| zutt | third and fourth are additional boosters | 12:47 |
| ublx | depends on the vaccine. it's three where i am. 2+1 booster | 12:47 |
| zutt | 52.07% complete vaccination, 75.6% have received at least one dose | 12:49 |
| zutt | Ukraine is sitting firmyl at ~35.5% for one dose, and ~35.5% for complete | 12:49 |
| ublx | further factors are the living conditions of unvaccinated people in bangladesh compared to what accommodations refugees can find, and the expected notion that refugees are those who have sufficient wealth to afford travel, and the expedient reach of heathcare services | 12:51 |
| ublx | if Lithuania had just said "the calculus of vaccine benefit for a refugee situation is complex" we'd have one less ugly thing to be aware of | 12:52 |
| zutt | according to google, avg deaths per day from covid is ~7 in Bangladesh currently | 12:56 |
| zutt | while aproximately ~300 civilians are dying every day in Ukraine (not counting in the soldiers from either side) | 12:56 |
| zutt | numbers may be wildly inaccurate ^ | 12:57 |
| zutt | and does not included the wounded at all ^ | 12:57 |
| ublx | actually the headline says "Lithuania ... after ... abstention" | 12:58 |
| ublx | it does not say "because" of abstention | 12:58 |
| zutt | good point | 12:59 |
| ublx | lrt.lt is the Lithuanian public broadcaster | 12:59 |
| ublx | the headline is their own rendition in english | 13:00 |
| ublx | the linked article offers no humanitarian interpretation other than the one implied | 13:00 |
| Brainstorm | Updates for Finland: +22369 cases, +184 deaths, +23663 tests (94.5% positive) since 2 days ago | 13:09 |
| Brainstorm | New from PubMed: How to continue COVID-19 vaccine clinical trials? The ethics of vaccine research in a time of pandemic: Between December 2020 and March 2021, the US Food and Drug Administration and the European Medicines Agency issued Emergency Use Authorizations and Conditional Marketing Authorizations for the distribution of the [... want %more?] → https://pubmed.ncbi.nlm.nih.gov/35250387/ | 13:33 |
| Brainstorm | Updates for Brunei: +4185 cases, +4 deaths since a day ago — Germany: +64671 cases since 23 hours ago | 13:59 |
| Brainstorm | New from r/COVID19: Weekly Scientific Discussion Thread - March 07, 2022: This weekly thread is for scientific discussion pertaining to COVID-19. Please post questions about the science of this virus and disease here to collect them for others and clear up post space for [... want %more?] → https://old.reddit.com/r/COVID19/comments/t8oohu/weekly_scientific_discussion_thread_march_07_2022/ | 14:02 |
| Brainstorm | New from BioNTech: Statement on Humanitarian Aid in Ukraine: Ugur Sahin, CEO and Co-Founder of BioNTech: “We at BioNTech are closely following the tragic situation in Ukraine and our thoughts are with everyone affected. As a company with employees from 60 countries, we [... want %more?] → https://investors.biontech.de/news-releases/news-release-details/statement-humanitarian-aid-ukraine | 14:41 |
| Brainstorm | Updates for Vanuatu: +23 cases since 9 days ago | 15:02 |
| Brainstorm | New from Reddit (test): nCoV: Global COVID Cases For 07MAR22 → https://old.reddit.com/r/nCoV/comments/t8pvul/global_covid_cases_for_07mar22/ | 15:10 |
| Brainstorm | New from StatNews: Pharma: STAT+: Pharmalittle: White House bid for Covid drug funding hurt by transparency issue; Bluebird Bio runs short of cash → https://www.statnews.com/pharmalot/2022/03/07/covid19-vaccine-cancer-bluebird-viiv-hiv-jnj-slaoui/ | 15:40 |
| Brainstorm | New from COVID on Twitter: Tulio de Oliveira (@Tuliodna): Below Tweet from 25 Dec highlighting that China would find it difficult to implement a Zero COVID policy with Omicron. Today China’s premier, Li Keqiang, said cities should not impose drastic measures to outbreaks but should respond in a “scientific & [... want %more?] → https://twitter.com/Tuliodna/status/1500846654378942468 | 15:59 |
| Brainstorm | Updates for Tonga: +104 cases since a day ago — Canada: +1309 cases, +13 deaths since 21 hours ago | 16:04 |
| Brainstorm | New from StatNews: Health: ‘We’re all in this together’: As long Covid studies continue, researchers cast a wider net → https://www.statnews.com/2022/03/07/long-covid-studies-continue-researchers-cast-wider-net/ | 16:09 |
| Brainstorm | New from COVID on Twitter: Loren Adler (@LorenAdler): As the declared Public Health Emergency nears its end, legislation will be needed to keep COVID-19 testing free at the point of care. twitter.com/LorenAdler/sta… → https://twitter.com/LorenAdler/status/1500851429430472705 | 16:28 |
| * FrauDoktor[m] uploaded an image: (134KiB) < https://libera.ems.host/_matrix/media/r0/download/matrix.org/NFhbuEpRlmEldfwPbNNLnsaj/-6138736450993238002_121.jpg > | 17:03 | |
| FrauDoktor[m] | Essen liegt an der Ruhr 🏰🏭🌊,... (full message at https://libera.ems.host/_matrix/media/r0/download/libera.chat/993534bc4243dde4b9e076c7d9f0edccb78af72e) | 17:03 |
| Brainstorm | New from ClinicalTrials.gov: (translated) (news): Myocarditis After SARS-CoV 2-Vaccination → https://clinicaltrials.gov/ct2/show/NCT05268458 | 17:07 |
| Brainstorm | New from ClinicalTrials.gov: (news): Vitamin D Nasal Drops in Post COVID Parosmia → https://clinicaltrials.gov/ct2/show/NCT05269017 | 17:57 |
| de-facto | %tr den Pieks und Schmerz den braucht man nicht, so wird die Impfung ein Gedicht, Nur bei Frau Doktor | 18:02 |
| Brainstorm | de-facto, German to English: you don't need the prick and pain, so the vaccination becomes a poem, only with a doctor (Google: 18%) — the pieks and pain you don't need, so the vaccination becomes a dense, only with women doctor (LibreTranslate: 11%) | 18:02 |
| Brainstorm | Updates for Germany: +78708 cases since 23 hours ago | 18:03 |
| de-facto | FrauDoktor[m] do you think it is helpful to have a vaccination preventing 4 of 5 hospitalizations for COVID infection? | 18:05 |
| pwr22 | Frau Doktor™️ 👩⚕️: as this is an international room please can you keep the discussion in English? | 18:10 |
| pwr22 | Also joining a room then immediately soliciting people elsewhere for dubious purposes isn't really ok and makes you seem like a spam bot so I'm going to remove those messages | 18:11 |
| Brainstorm | New from COVID on Twitter: Eric Topol (@EricTopol): The epidemic of Covid complacencyerictopol.substack.com/p/the-epidemic…Isn’t it great? The pandemic is over. We don’t need masks. The virus is contained. Forget about vaccines since they don’t work. The vulnerable are protected. Future variants will be [... want %more?] → https://twitter.com/EricTopol/status/1500881354749136896 | 18:16 |
| LjL | Lolwut | 18:41 |
| oerheks | LjL, ys, eric topol | 18:42 |
| LjL | Wasn't talking about that... | 18:43 |
| lastshell | epidemic is over ? | 18:44 |
| lastshell | what about new crazy varians ? | 18:45 |
| LjL | Groan | 18:45 |
| LjL | People really do need to use gigantic sarcasm tags don't they | 18:45 |
| Brainstorm | New from r/COVID19: COVID19: SARS-CoV-2 is associated with changes in brain structure in UK Biobank → https://old.reddit.com/r/COVID19/comments/t8us09/sarscov2_is_associated_with_changes_in_brain/ | 18:45 |
| xx | hmm, so even topol admits its over? | 18:46 |
| xx | nice | 18:46 |
| LjL | Jesus Christ no | 18:46 |
| xx | :p | 18:46 |
| LjL | %slap xx | 18:46 |
| * Brainstorm roundhouse kicks xx | 18:46 | |
| xx | heh | 18:46 |
| LjL | Like literally *sigh*...ma | 18:47 |
| xx | %search iodine | 18:49 |
| Brainstorm | xx, 83000000.0 hits: https://en.wikipedia.org/wiki/Iodine (Iodine) | 18:49 |
| xx | well that's not what I wanted | 18:49 |
| LjL-Matrix | Aufnichtwiedersehen Frau Doktor! | 19:00 |
| xx | to not see you again miss doctor? | 19:01 |
| LjL | Ja | 19:01 |
| xx | ich bin ein Kartoffel, ja | 19:01 |
| LjL | Mit beinen und halb ein Hirne | 19:02 |
| xx | wonder what the longest german word is that contains coronavirus | 19:02 |
| bin | wie ist katoffel en Englische? | 19:02 |
| de-facto | Die Kartoffel ist weiblich | 19:02 |
| xx | das Mädchen ist weiblich | 19:03 |
| LjL | Anticoronavirusimpfungshesitation | 19:03 |
| xx | Gegencoronavirusimpfungshesitation | 19:03 |
| LjL | Gegege | 19:03 |
| LjL | xx: das Mädchen is actually neuter tho | 19:04 |
| LjL | But I guess ttj | 19:04 |
| xx | LjL: every Mädchen should be neutered, you're right | 19:04 |
| de-facto | bin potato | 19:04 |
| darsie | *chen is neutral. | 19:06 |
| lastshell | I'm not German but looks like people is happy because covid is over | 19:06 |
| xx | /!\ COVID IS OVER /!\ | 19:07 |
| lastshell | this is an awesome feeling to be honenest | 19:08 |
| * xx puts on the mask and walks out into the nuclear wasteland in search of food, with fond memories of the pandemic | 19:08 | |
| Tuvix | The continued death toll is awesome, lastshell? Have you actually read the post Topol made? | 19:08 |
| lastshell | :( | 19:08 |
| Tuvix | I think you've read a sarcastic, tonge-in-cheek title and assumed it was the entire article. | 19:09 |
| lastshell | oh no | 19:09 |
| LjL | xx: you're lucky Brainstorm is not opped | 19:09 |
| Tuvix | If this is the case, perhaps you should read his full page; it's worth reading. | 19:09 |
| xx | LjL: heh, is that on autokick list? | 19:09 |
| LjL | Yep | 19:09 |
| lastshell | but is getting better right ? | 19:09 |
| xx | guess I'm not the first one to say such nonsense then | 19:10 |
| LjL | xx: with covid, you might be | 19:10 |
| xx | anyway, it's not over, but people once more behave as if it were | 19:10 |
| xx | so what's to be done? | 19:10 |
| lastshell | is like ignore the virus so the virus will ignore us a approach ? | 19:11 |
| Tuvix | lastshell: Depends a bit on where you are. In the US the numbers are improving, but only becuase we're coming off a really bad peak. Latest numbers from Saturday's rolling average of death put the US at a *higher* rate of daily death than the pandemic average. | 19:11 |
| Tuvix | So, in terms of death, "getting better" is relative because we're doing worse than average over the entier pandemic if you consider lives lost to be a metric worth considering, as I do. | 19:11 |
| xx | Tuvix: in these parts, and surrounding parts (eastern europe), covid receives zero news coverage now | 19:11 |
| lastshell | why the CDC is relaxing measures ? | 19:11 |
| bin | de-facto: ty | 19:11 |
| bin | vocab is never my strong suit but i recognized it from duolingo xD | 19:12 |
| Tuvix | Relaxing measures is complicated, becuase it's a factor of political, social feeling, and science. Sadly, the first 2 often win out over the latter ones. However, restrictions that people were already ignoring largely aren't effective either, so there's not a lot of point to continuing rules that aren't effective either. | 19:13 |
| Tuvix | Most of the "restrictions" in the US were only guidance anyway. Nothing the CDC did was ever mandatory unless a state or local government made it so, at least as far as citizen action went. Around me, even isolation after testing positive was the "guidance" and not required or enforced. | 19:14 |
| Brainstorm | New from COVID on Twitter: Prof. Akiko Iwasaki (@VirusesImmunity): After over two years of COVID pandemic, we need a vision for how to navigate the #NextNormal. Honored to contribute to this roadmap led by @ZekeEmanuel with many colleagues - including @hmkyale @ktkadakia @PutrinoLab on #LongCOVID, with [... want %more?] → https://twitter.com/VirusesImmunity/status/1500895502266626048 | 19:14 |
| lastshell | I'm the few that still wears masks indoors going to the super market | 19:15 |
| lastshell | people think im weirdo | 19:15 |
| Tuvix | As far as why the CDC is doing that, it's also complicated; many states were also moving that direction, and the CDC risks even fewer people following guidance if they're seen by most of the public as being too far behind public desires here. | 19:15 |
| Tuvix | The CDC's updated guidnace basically reclassifies all counties by different standards of severity, but my big problem (and many others who worry about new VoCs or another summer-surge like Delta) is that the "new" metrics the CDC is using are largely reactive. | 19:16 |
| Tuvix | To move a county to higher-risk categories, measures like hospital use are given more priority. These *are* good data-points, but they're reactive, which means after disease is already a big problem, some weeks later hospital cases rise. | 19:17 |
| lastshell | so is like now we are ok to having covid becasue we are more worried about nuclear war ? | 19:17 |
| Tuvix | It's a bit like suggesting that if you crash your car you should then make sure your seatbelt is on. | 19:17 |
| lastshell | where i am is a red state | 19:17 |
| lastshell | very few people use masks | 19:17 |
| Tuvix | The Russian-inspired war is certainly a big part of the reason COVID is no longer getting as much news coverage, yes. Combine that with metrics that are generally improving and wishful thinking that we won't see another wave (we already saw the original, then Alpha, the Delta in summer which we never recovered from in the US, then Omicron.) | 19:18 |
| lastshell | Tuvix how feasible is to have a new "Delta" (similar variant) wave this summer ? | 19:18 |
| xx | is Sigma really going to be something of concern? | 19:19 |
| Tuvix | I don't see anything preventing that from happening again. The emergence of the VoC was what drove that, but lower vaccination rates in the US (vs. other places) made our impact from Delta worse than it otherwise would have been. | 19:19 |
| Tuvix | You can see that the US was poorly poised here if you compare virtually any other modern country to the US and see the impact of Delta other places far lower. It wasn't "good" in places like Canada or most of Europe either, but it was "a lot less bad" | 19:20 |
| lastshell | damn I was going to schedule a buffet for birthyday party but I guess I will hold for now | 19:20 |
| Tuvix | So, sure, nothing stops another summer wave. Presumably a VoC would need to emerge, or immunity wanes enough for re-infection of the prevailing varient. | 19:20 |
| Tuvix | I mean, indoor gatherings can be made safer depending on how you approach them, and at the moment Omicron is still the prevailing varient, although BA.2 has some immune-escape compared to the original Omicron strain. | 19:21 |
| lastshell | if Im younger than 40 and had omicron and had the 3 jabs im ok to no worry to much ? | 19:21 |
| Tuvix | BA.1 confers *some* protection against BA.2, but less than against another BA.1. | 19:21 |
| Tuvix | As far as your personal risk, you have fairly low risk of severe complications assuming no co-morbidities. Long-covid seems to be a larger unknown, since its effects are less consistent and its underlying causes still not yet well-understood | 19:22 |
| lastshell | yeah, I found when I workout very hard my blod pressure stay high | 19:22 |
| Tuvix | Just remember that the vaccines don't have all that great effectiveness against catching COVID, but have very good protection aginst severe disease and do offer some reduction in long-covid or at least the severity of its symptoms based on current studies. | 19:23 |
| lastshell | I found regular ligth walking helps me to reduce the blood pressure | 19:24 |
| lastshell | not sure if that long covid or Im doing bad workouts | 19:24 |
| Tuvix | Being active is something almost any doctor will tell you to do as soon as you feel able after recovering from most illnesses; the body doesn't do well stuck in bed or on the couch. | 19:25 |
| lastshell | yeah | 19:25 |
| Tuvix | One of the first things patients out of surgery are encouraged to do after they begin to recover is walk around, even if it's just down the hall a ways and back to bed. | 19:25 |
| Tuvix | (obviously that depends on the surgery, but this is a general statement; someone at risk of harm if they move are kept in bed longer, but the body pays a price for that.) | 19:26 |
| lastshell | yeah mom got some surgery last years and doctor encourage to walk afer the surgery | 19:27 |
| lastshell | I rememebr that | 19:27 |
| Tuvix | If you noticed a change in your own physical response, only a doctor could evaluate your own symptoms though. What, if any, symptoms recovered COVID patients have and for how long varies quite a lot. | 19:27 |
| lastshell | I want todo a blood test | 19:28 |
| lastshell | someone suggested the other day to donate blood after recover from covid | 19:29 |
| lastshell | to reduce viscosity | 19:29 |
| xx | donating blood in general is a good idea if you're found eligible | 19:34 |
| Brainstorm | New from COVID on Twitter: Eric Topol (@EricTopol): A 1-year prospective, multi-center study of #LongCovid moderate-severe symptoms in adults, teens, and children with controls: persistence in adults and in teen girls, not in children less than age 14papers.ssrn.com/sol3/papers.cf… pic.twitter.com/Gf0g4GuiKL → https://twitter.com/EricTopol/status/1500903215319060481 | 19:44 |
| Brainstorm | New from COVID on Twitter: Michael Lin, MD PhD (@michaelzlin): The problem is a simple one: In HK, "at the start of this year, just 25% of people age 80 or over had been vaccinated." That's amazingly bad.In NZ, it's >90%.The reason was widespread word-of-mouth fears about vaccine side effects among the [... want %more?] → https://twitter.com/michaelzlin/status/1500906805492207619 | 19:54 |
| Brainstorm | Updates for United Kingdom: +126196 cases, +139 deaths since 2 days ago — Italy: +22662 cases, +130 deaths, +188274 tests (12.0% positive) since a day ago | 20:02 |
| Brainstorm | New from COVID on Twitter: Michael Lin, MD PhD (@michaelzlin): A last thing to appreciate is that although Omicron is less lethal than Delta, it's not discernably different from the original strain. (That's across all ages; not clear how it breaks down by age.) So the high death rates for unvaxxed is not [... want %more?] → https://twitter.com/michaelzlin/status/1500908889188962308 | 20:04 |
| Brainstorm | New from Reddit (test): Covid2019: These US counties still have 'high' Covid-19 levels as their states lift mask mandates, CNN analysis shows - there are still about 472 counties nationwide where mask-wearing is recommended → https://old.reddit.com/r/Covid2019/comments/t8wvij/these_us_counties_still_have_high_covid19_levels/ | 20:24 |
| Brainstorm | New from Contagion Live: Pivotal Trial Data Supports Viral Vector Vaccine against SARS-CoV-2: Final analysis of phase 3, placebo-controlled trial confirms efficacy and safety of single-dose adenoviral vector vaccine against COVID-19. → https://www.contagionlive.com/view/pivotal-trial-data-supports-viral-vector-vaccine-against-sars-cov-2 | 21:02 |
| Brainstorm | New from r/COVID19: COVID19: Combination of antiviral drugs inhibits SARS-CoV-2 polymerase and exonuclease and demonstrates COVID-19 therapeutic potential in viral cell culture → https://old.reddit.com/r/COVID19/comments/t8y42j/combination_of_antiviral_drugs_inhibits_sarscov2/ | 21:11 |
| Brainstorm | New from COVID on Twitter: (translated) Commissioner Dave A. Chokshi, MD (@NYCHealthCommr): !Since our COVID-19 vaccination campaign began, we estimate 48,000 lives have been saved — and an immense amount of suffering avoided — due to vaccines.More on the study: on.nyc.gov/3sE6R6S pic.twitter.com/e2Mxt5v7dB → https://twitter.com/NYCHealthCommr/status/1500931942493077511 | 21:45 |
| Brainstorm | New from COVID on Twitter: Eric Topol (@EricTopol): Good review of findings/explainer @NYTScience nytimes.com/2022/03/07/hea… by @PamBelluck One thing missed is the influence of the viral strain. Since Omicron induced far less loss of smell, any hit to brain was likely markedly reduced or null. Tropism to organs [... want %more?] → https://twitter.com/EricTopol/status/1500938042613194752 | 22:04 |
| Brainstorm | Updates for Spain: +35997 cases, +143 deaths since 3 days ago — Canada: +2935 cases, +25 deaths since 23 hours ago — United Kingdom: +401 cases, +1 deaths since 2 hours ago | 22:08 |
| Brainstorm | New from COVID on Twitter: Scott Gottlieb, MD (@ScottGottliebMD): New York Times: “Covid May Cause Changes in the Brain, New Study Finds - Brain scans before and after infection showed more loss of gray matter and tissue damage, mostly in areas related to smell, in people who had Covid than in those who did [... want %more?] → https://twitter.com/ScottGottliebMD/status/1500940042394550275 | 22:14 |
| Brainstorm | New from CIDRAP: COVID deaths vary by race, community, social factors: Mary Van Beusekom | News Writer | CIDRAP News Mar 07, 2022 Social determinants of health tied to COVID-19 death rates vary by race and community type, a new study finds. → https://www.cidrap.umn.edu/news-perspective/2022/03/covid-deaths-vary-race-community-social-factors | 22:24 |
| Tuvix | .title https://www.nejm.org/doi/full/10.1056/NEJMp2119682 | 22:44 |
| Brainstorm | Tuvix: From www.nejm.org: Challenges in Inferring Intrinsic Severity of the SARS-CoV-2 Omicron Variant | NEJM | 22:44 |
| Tuvix | "… omicron was about 75% as likely as delta to cause hospitalization in an unvaccinated person with no history of SARS-CoV-2 infection […] This meaningful but fairly small difference implies that omicron, alpha, and wild-type SARS-CoV-2 have similar intrinsic severity." | 22:44 |
| Tuvix | "Although the reduced [case fatality rate] seen in the early weeks of [SA]'s omicron-variant wave is better than the alternative, much of the observed difference relates to increased immunity among the people being infected." | 22:44 |
| Timvde | That's pretty much what I expected tbh | 22:45 |
| Tuvix | This hints that any country could become the next Hong Kong in terms of renewed outbreak if there's significant immune-escape in a population with enough having little-to-no prior immunity. | 22:46 |
| Timvde | Question: a friend of mine read something about blood type being correlated with severity (with A being more susceptible than O). Last I heard was 1.5 years ago that it probably wasn't true. Are there any new updates regarding that? | 22:47 |
| Tuvix | I'm only aware of one study offhand, but it was very limited on conclusions and merely hinted that it could be a factor, but didn't draw direct conclusions. | 22:52 |
| Tuvix | .title https://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1010042 | 22:52 |
| Brainstorm | Tuvix: From journals.plos.org: Proteome-wide Mendelian randomization identifies causal links between blood proteins and severe COVID-19 | 22:52 |
| Tuvix | "However, the pre- cise blood group associated with the increased risk for hospitalization as a result of COVID-19 cannot be determined from our results, as the probe for the blood marker measures both the A and B isoform of the protein while not showing a signal for O." | 22:53 |
| LjL | A new thing about that was posted yesterday | 22:54 |
| LjL | Mainly outlining a supposed mechanism I think, in vitro stuff | 22:54 |
| LjL | Can't grep logs right now but it's positively in the logs of yesterday or today | 22:54 |
| Timvde | I found this in the backlog, let's see: https://old.reddit.com/r/science/comments/t8dkz2/genetic_study_reveals_causal_link_between_blood/ | 22:55 |
| Tuvix | The "new study" they cite is the same as the one I linked; that study came out on the 3rd of this month, just a few days ago. | 22:56 |
| Tuvix | "Nevertheless, it is more likely that A, B, or the combination of A and B is associated with higher risk for hospitalization. […] All evi- dence taken together suggests that blood group A is the more likely candidate for follow-up studies." | 22:57 |
| Tuvix | So, I'm reading from that basically there could be some link, but their results don't directly point to it and indicate the need to study the relationship further. | 22:57 |
| Tuvix | I don't quite grasp what the "proxy" they refer to means though: | 23:00 |
| Tuvix | "we selected genetic variants, single nucleotide polymorphisms (SNPs), that were strongly associated with actual blood protein levels in 5,504 genome-wide analyses of single proteins …" | 23:00 |
| Tuvix | "Using these genetic loci as proxies for protein levels, we performed an analysis using Mendelian randomization, a method that enables tests of putative causal associations of these blood proteins with the development of severe COVID-19." | 23:00 |
| Tuvix | Later, | 23:01 |
| Tuvix | "We needed to take this analytical step as GWAS of blood pro- teins with more statistical power are not available at this time." | 23:01 |
| Brainstorm | New from CIDRAP: Health groups press for more wildlife SARS-CoV-2 tracking: Lisa Schnirring | News Editor | CIDRAP News Mar 07, 2022 Concerns are growing that continued spread could create COVID-19 virus reservoirs in animals. → https://www.cidrap.umn.edu/news-perspective/2022/03/health-groups-press-more-wildlife-sars-cov-2-tracking | 23:03 |
| Brainstorm | Updates for Germany: +115969 cases since 23 hours ago | 23:10 |
| Brainstorm | New from CIDRAP: Experts map out 'new normal' as US enters third pandemic year: Stephanie Soucheray | News Reporter | CIDRAP News Mar 07, 2022 The roadmap advises against school closings, lobbies for more tests, and details when restrictions should lift. → https://www.cidrap.umn.edu/news-perspective/2022/03/experts-map-out-new-normal-us-enters-third-pandemic-year | 23:13 |
| Brainstorm | New from COVID on Twitter: Eric Topol (@EricTopol): "Developing high-quality scientific evidenceon PASC [@LongCovid] presents a unique challenge due to the evolving circumstances of SARS-CoV-2 and the pandemic itself. Such work will indeed be a long haul." acpjournals.org/doi/10.7326/M2…@LaurenWisk @JoannElmoreMD [... want %more?] → https://twitter.com/EricTopol/status/1500959375472529410 | 23:22 |
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