libera/##covid-19/ Thursday, 2022-04-21

-Bridgestorm- 🏠 Linog! Lindol! Earthquake! 6.0 Mww tremor, registered by US, occurred 22 minutes ago (21:57:46 UTC), during daytime, Manay, Philippines (6.98, 126.95), ↓51 km likely felt 270 km away (in Manay, Caraga, Mati, Tarragona…) by 256800 people (service.iris.edu)00:20
BrainstormNew from Reddit (test): nCoV: Herd immunity against virus at 50% | 20APR22 → https://old.reddit.com/r/nCoV/comments/u8890u/herd_immunity_against_virus_at_50_20apr22/00:31
BrainstormNew from WebMD: 30% of COVID Patients in Study Developed ‘Long COVID’: People with a history of hospitalization, diabetes, and higher body mass index were most likely to develop long COVID, researchers said.  The kind of insurance the patients had also seemed to be a [... want %more?] → https://www.webmd.com/lung/news/20220420/30-percent-of-covid-patients-in-study-developed-long-covid00:41
BrainstormUpdates for Brazil: +32699 cases, +18 deaths since 22 hours ago — Trinidad and Tobago: +405 cases, +1 deaths since a day ago01:01
BrainstormNew from BBC Health: Covid: Woman caught virus twice within record 20 days: Spanish researchers say it's the shortest-known gap between two coronavirus infections. → https://www.bbc.co.uk/news/health-6116152901:58
BrainstormUpdates for Germany: +117377 cases, +361 deaths since 20 hours ago — Canada: +10365 cases, +106 deaths since 22 hours ago02:04
BrainstormNew from COVID on Twitter: Lawrence Gostin (@LawrenceGostin): CDC's power to prevent interstate spread of #SARSCoV2 is as basic as you can get. CDC used a far less restrictive alternative by only requiring masking. CDC has the undoubted power to quarantine to prevent interstate spread. Surely it could chose a [... want %more?] → https://twitter.com/LawrenceGostin/status/151693007501440204802:27
as83n54kdh02:28
BrainstormNew from COVID on Twitter: Dan Diamond (@ddiamond): Public health experts like @LawrenceGostin had exhorted Biden admin to appeal, saying the Florida judge’s ruling was flawed + CDC needed to ensure it had authority for future crises.But the court battles ahead could backfire on White House, having lost on covid [... want %more?] → https://twitter.com/ddiamond/status/151694199163189248102:56
BrainstormUpdates for Samoa: +485 cases, +5850 tests since a day ago03:01
BrainstormNew from COVID on Twitter: Michael Lin, MD PhD   (@michaelzlin): This has implications for test-and-treat too. Perhaps not ideal to give Paxlovid on-the-spot with a (+) test on day 1 of symptoms. Might work better to tell patients to come back for a Paxlovid prescription if their symptoms don't improve by day 3 [... want %more?] → https://twitter.com/michaelzlin/status/151694493688879923203:06
BrainstormNew from Reddit (test): nCoV: Health worker infected with Covid twice in 20 days after catching both Delta and Omicron | 20APR22 → https://old.reddit.com/r/nCoV/comments/u8bshn/health_worker_infected_with_covid_twice_in_20/03:25
BrainstormNew from COVID on Twitter: Michael Lin, MD PhD   (@michaelzlin): If a patent application for the idea hadn't already been submitted as of today, that allows anyone to test the idea with any combination of vaccines and drugs without worrying that one company will be granted a monopoly on the approach with their [... want %more?] → https://twitter.com/michaelzlin/status/151695393184213402203:45
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): The US BA.2 wave: Although still < 14,000, Covid hospitalizations are now on the upswing for multiple days with > 400 more added today pic.twitter.com/omCmgVVBLV → https://twitter.com/EricTopol/status/151695710479536128103:54
BrainstormUpdates for Australia: +51610 cases, +33 deaths since 22 hours ago — United Kingdom: +27321 cases since 22 hours ago04:03
BrainstormNew from COVID on Twitter: Josiah 'So Mild' Grindrod (@JT_Grindrod): Lmao for @DrLeanaWen there is literally no bottom. twitter.com/MarkedByCovid/… → https://twitter.com/JT_Grindrod/status/151696631063416422904:33
BrainstormUpdates for Barbados: +674 cases, +1878 tests since a day ago05:06
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): Denmark nationwide data on vaccine effectiveness (VE) vs Omicron and previous variantsmedrxiv.org/content/10.110…The 3rd shot achieved VE of ~50% vs Omicron infections and high protection vs Omicron hospitalization out to 4 months, especially in people age 60+ [... want %more?] → https://twitter.com/EricTopol/status/151697862943076352005:21
de-facto%title https://www.bbc.com/news/health-6116152905:38
Brainstormde-facto: From www.bbc.com: Covid: Woman caught virus twice within record 20 days - BBC News05:38
BrainstormUpdates for Thailand: +21931 cases, +129 deaths since a day ago — New Zealand: +14775 cases, +18 deaths since 22 hours ago — Germany: +119926 cases since 12 hours ago — Canada: +13433 cases since 13 hours ago06:02
BrainstormNew from This Week In Virology: TWiV 891: LLOV in the time of Ebola: Elke, Adam, and Gabor join TWiV to discuss their work on Lloviu virus, a filovirus, including recovery of infectious virus from a DNA copy of the genome and from Schreiber’s bats in Hungary. → https://www.microbe.tv/twiv/twiv-891/06:09
BrainstormNew from COVID on Twitter: Sofonias K Tessema (@sofoniaskt): A continent wide collaboration on SARS-COV-2 sequencing. Thank you @houzhou @EduanWilkinson and everyone who contributed to this work. @AfricaPGI twitter.com/houzhou/status… → https://twitter.com/sofoniaskt/status/151699076473105612807:56
BrainstormUpdates for Sao Paulo, Brazil: +14445 cases, +109 deaths since 2 days ago — Lombardy, Italy: +14065 cases, +24 deaths since 23 hours ago — Campania, Italy: +12275 cases, +18 deaths since 23 hours ago — Lazio, Italy: +10681 cases, +14 deaths since 23 hours ago08:01
BrainstormNew from COVID on Twitter: Michael Lin, MD PhD   (@michaelzlin): HBV is one virus where you can vaccinate after exposure or inoculation. This is done to accelerate the emergence of immunity in cases where one gets exposed by needleprick to HBV+ blood. HBV starts slow in stealth mode; we can consider [... want %more?] → https://twitter.com/michaelzlin/status/151701934210109030408:05
BrainstormNew from r/Coronavirus: Daily Discussion Thread | April 21, 2022: Please refer to our Wiki for more information on COVID-19 and our sub. You can find answers to frequently asked questions in our FAQ , where there is valuable information such as our: → https://old.reddit.com/r/Coronavirus/comments/u8hjrr/daily_discussion_thread_april_21_2022/09:02
BrainstormNew from COVID on Twitter: Michael Lin, MD PhD   (@michaelzlin): Always nice when other scientists use our tools, in this case the Fucci4 fluorescent reporter of 4 cell cycle phases. From a different pre-pandemic scientific life! twitter.com/GloerichLab/st… → https://twitter.com/michaelzlin/status/151703980084640563209:22
BrainstormUpdates for Taiwan: +3057 cases since a day ago10:00
-Bridgestorm- ⭕ Sismo! Earthquake! 6.8 Mi tremor, registered by AT,PT, occurred 17 minutes ago (07:42:51 UTC), during a gibbous moon night, Masachapa, Nicaragua (11.5, -87.0), ↓10 km likely felt 460 km away (in León, Jinotepe…) by 211600 people (service.iris.edu)10:01
BrainstormNew from COVID on Twitter: Tom Peacock (@PeacockFlu): Delighted to have been a (very tiny!) part of this super interesting work about how some SARS-CoV-2 variants can express novel proteins through altering their RNA sequences! Great thread by @DavidLVBauer below! twitter.com/DavidLVBauer/s… → https://twitter.com/PeacockFlu/status/151705232075594957210:10
BrainstormNew from r/COVID19: COVID19: Covid-19 Vaccine Effectiveness against the Omicron (B.1.1.529) Variant → https://old.reddit.com/r/COVID19/comments/u8ixt2/covid19_vaccine_effectiveness_against_the_omicron/10:59
BrainstormNew from ProPublica: Look Up Nursing Home Staff COVID-19 Vaccination Rates: by Ruth Talbot ProPublica is a nonprofit newsroom that investigates abuses of power. Sign up to receive our biggest stories as soon as they’re published. On Thursday, ProPublica added staff COVID-19 vaccination data to [... want %more?] → https://www.propublica.org/nerds/nursing-home-vaccination-rates-covid#131708911:48
BrainstormNew from COVID on Twitter: Tom Wenseleers (@TWenseleers): The pace at which BA.4 & BA.5 take over from BA.2 is about the same as that at which BA.2 took over from BA.1. But with the difference that unlike BA.2, BA.4 & 5 likely have some immune escape & will therefore cause a wave of reinfections. Severity to be [... want %more?] → https://twitter.com/TWenseleers/status/151707953302700851211:58
BrainstormUpdates for Finland: +50889 cases, +121 deaths, +53163 tests since 6 days ago — Israel: +4043 cases since 23 hours ago12:00
BrainstormNew from COVID on Twitter: Tom Wenseleers (@TWenseleers): Plenty of scope for random founder effects this time around: the logistic growth advantage of BA.4 & BA.5 over BA.2 is both 0.11 per day [0.08-0.13] 95% CLs, similar to the advantage of Delta over Alpha. No idea which of those two will conquer the world [... want %more?] → https://twitter.com/TWenseleers/status/151708083474603212812:08
BrainstormNew from BBC Health: (news): NHS Wales and Covid: A&E departments under 'relentless pressure' → https://www.bbc.co.uk/news/uk-wales-6116930312:47
BrainstormNew from r/COVID19: COVID19: The evolving SARS-CoV-2 epidemic in Africa: Insights from rapidly expanding genomic surveillance. → https://old.reddit.com/r/COVID19/comments/u8l5p1/the_evolving_sarscov2_epidemic_in_africa_insights/13:56
BrainstormNew from COVID on Twitter: Derek Thompson (@DKThomp): Great airplane-mask-COVID thread. TLDR:1. Planes have high-quality ventilation tech.2. Very few outbreaks attributable to planes.3. But ventilation is off during de/boarding. 4. Masks during boarding and planes turning on vents early would let maskless flight [... want %more?] → https://twitter.com/DKThomp/status/151710662073567232114:05
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): The BA.2 wave in the United States is soon morphing to the BA2.12.1 wave, a derivative variant with even more fitness and transmission advantage twitter.com/JPWeiland/stat… → https://twitter.com/EricTopol/status/151711366925080576114:15
BrainstormNew from EMA: Human medicine assessment reports: (news): Human medicines European public assessment report (EPAR): Pregabalin Pfizer, pregabalin, Anxiety Disorders;Epilepsy, Date of authorisation: 10/04/2014, Revision: 27, Status: Authorised → https://www.ema.europa.eu/en/medicines/human/EPAR/pregabalin-pfizer14:46
LjL%tr Si riconferma l’impossibilità di determinare con precisione l’entità del calo epidemico: per la terza settimana consecutiva la diminuzione dei casi individuati replica in modo quasi integrale la diminuzione dei test eseguiti.15:09
BrainstormLjL, Italian to English: The impossibility of accurately determining the extent of the epidemic decline is reconfirmed: 99.99 for the third consecutive week the decrease in cases identified almost completely replicates the decrease in tests performed. (Google: 18%) [... want %more?]15:09
LjLI like this site because it says the obvious things15:09
LjLSeems like a low bar but isn't15:09
LjL%tr Per questo motivo reiteriamo l’invito a utilizzare il più possibile le mascherine Ffp2, anche all’aperto se in presenza di altre persone: sono l’unico strumento che si affianca al vaccino nel proteggerci dall’infezione (contro tutte le varianti note) e non trova alcuna spiegazione la rinuncia a utilizzarlo.15:11
BrainstormLjL, Italian to English: For this reason we reiterate the invitation to use the Ffp2 masks as much as possible, even outdoors if in the presence of other people: they are the only tool that supports the vaccine in protecting us from infection (against all known variants) and the renunciation of using it finds no explanation. (Google: 18%) [... want %more?]15:11
BrainstormNew from StatNews: Pharma: STAT+: U.S. spending on pharmaceuticals jumped 12% in 2021, fueled by costs of Covid-19 vaccines and therapies → https://www.statnews.com/pharmalot/2022/04/21/covid19-vaccine-insulin-prescriptions-biosimilar-generics/15:15
BrainstormNew from Politico: Boris Johnson caves and allows Partygate scandal probe: Move comes amid anger in Johnson’s own ranks at being asked to defend lockdown breach. → https://www.politico.eu/article/boris-johnson-caves-to-allow-partygate-probe/15:34
BrainstormNew from Il Sole 24 Ore: (translated) From Bei 15 million to Irbm for research on infectious and rare diseases: The goal is to help ensure a more resilient global response against future epidemics, by producing second generation vaccines and treatments not only for [... want %more?] → https://www.ilsole24ore.com/art/dalla-bei-15-milioni-irbm-la-ricerca-malattie-infettive-e-rare-AEl4OTTB16:04
BrainstormUpdates for Belarus: +695 cases, +3 deaths, +13549 tests since a day ago — Canada: +12910 cases, +85 deaths since 20 hours ago16:04
BrainstormNew from Reddit (test): Covid2019: A puzzling phenomenon: Patients report a rebound of COVID-19 symptoms after taking the antiviral Paxlovid - The Boston Globe → https://old.reddit.com/r/Covid2019/comments/u8ofnx/a_puzzling_phenomenon_patients_report_a_rebound/16:14
BrainstormNew from COVID on Twitter: Scott Gottlieb, MD (@ScottGottliebMD): Many parents are waiting a long time - especially those with children who have pre-existing health conditions - to offer them the additional protections that safe and effective vaccines could provide. We must work together to help advance timely [... want %more?] → https://twitter.com/ScottGottliebMD/status/151714687683064217616:34
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): Good graphic for how Omicron (and its various BA. family lineages) gets into cells, which differs from prior variants. A nice explainer for its hyper-contagiousnessscientificamerican.com/article/omicro… @sciam by @Scudellari and @FalconieriV pic.twitter.com/terCf2x0p3 → https://twitter.com/EricTopol/status/151714926070524314216:44
BrainstormNew from ClinicalTrials.gov: (news): Computer Cognitive Training for Post-acute COVID-19 Syndrome → https://clinicaltrials.gov/ct2/show/NCT0533874917:14
BrainstormNew from ClinicalTrials.gov: (news): Pilot Trial on Immunosuppression Modulation to Increase SARS-CoV-2 Vaccine Response in Kidney Transplant Recipients → https://clinicaltrials.gov/ct2/show/NCT0533817717:24
BrainstormUpdates for Germany: +139849 cases, +260 deaths since 15 hours ago18:03
BrainstormNew from ClinicalTrials.gov: (news): TekiTrust Tests to Determine the Level of SARS-COV-2/COVID-19 Neutralizing Antibodies in the Blood → https://clinicaltrials.gov/ct2/show/NCT0533876218:04
BrainstormNew from ClinicalTrials.gov: (news): Humoral and Cellular Immunity in First-cycle SARS-CoV-2 Vaccinated COVID-19 Patients → https://clinicaltrials.gov/ct2/show/NCT0533873618:13
BrainstormNew from COVID on Twitter: Prof. Akiko Iwasaki (@VirusesImmunity): Very excited to work with @kindred_health and @hmkyale on @YaleMed LISTEN study to better understand the phenotypes and underlying pathogenesis of #longCOVID. Please join us and work with us on this important endeavor together at [... want %more?] → https://twitter.com/VirusesImmunity/status/151717498291218842318:23
BrainstormNew from ProPublica: Conditions at Mississippi’s Most Notorious Prison Violate the Constitution, DOJ Says: by Jerry Mitchell , Mississippi Center for Investigative Reporting This article was produced by the Mississippi Center for Investigative [... want %more?] → https://www.propublica.org/article/conditions-at-mississippis-most-notorious-prison-violate-the-constitution-doj-says#131720918:43
BrainstormUpdates for Canada: +16378 cases, +100 deaths since 23 hours ago19:06
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): Uptick due to BA.2 and BA.2.12.1 as seen via log-plots with acknowledgment of gross under-reporting. BA.2.12.1 will out-compete, become dominant in the next few weeks pic.twitter.com/8Ra1cMps4r → https://twitter.com/EricTopol/status/151718876601994854419:12
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): Mutation map of the BA family subvariants: BA.2.12.1 in the US; BA.4 and BA.5 in South Africa and other countries, that are outcompeting BA.2 and leading to new case increases. There are some key differences outbreak.info twitter.com/EricTopol/stat… pic.twitter.com/cNLqcQ1zZT → https://twitter.com/EricTopol/status/151718994729953280119:22
BrainstormNew from WebMD: Is the Opioid Crisis Masking Real Rates of Suicides?: Experts were optimistic at first, pointing to a number of potential drivers for the 3% drop in suicides nationally. But many believe the opioid epidemic is masking many deaths that in truth were suicides. → https://www.webmd.com/mental-health/addiction/news/20220421/is-the-opioid-crisis-masking-real-rates-of-suicide19:41
BrainstormUpdates for Japan: +43693 cases, +52 deaths since 12 hours ago — United Kingdom: +19719 cases, +646 deaths since 21 hours ago20:02
BrainstormNew from COVID on Twitter: Marc Veldhoen (@Marc_Veld): How China’s Sinovac compares with BioNTech’s mRNA vaccineSinovac is not as powerful as BioNTech; however, a 3rd dose is equally powerful; unfortunately, the vaccination rate is not high.  economist.com/graphic-detail… → https://twitter.com/Marc_Veld/status/151720269282902835520:11
BrainstormNew from COVID on Twitter: Marc Veldhoen (@Marc_Veld): Vaccine effectiveness against SARS-CoV-2 infection and COVID-19-related hospitalization with the Alpha, Delta and Omicron SARS-CoV-2 variants.3rd dose; 50% protection against infection; after 4 months; high protection against disease and death.medrxiv.org/content/10.110… → https://twitter.com/Marc_Veld/status/151720444825005671320:21
BrainstormNew from COVID on Twitter: Adam Cancryn (@adamcancryn): @AmyDashTV @pfizer @ScottGottliebMD @US_FDA @moderna_tx Amy, I reported and wrote the article discussed here — your assertions are 100% wrong and actively misinforming parents. The article very specifically details what factors FDA is actually considering in [... want %more?] → https://twitter.com/adamcancryn/status/151720729176173363420:40
BrainstormNew from CIDRAP: News Scan for Apr 21, 2022: Omicron on heels Delta infection Fewer Australian antibiotics during COVID Hepatitis in UK kids A million malaria vaccinations → https://www.cidrap.umn.edu/news-perspective/2022/04/news-scan-apr-21-202221:00
BrainstormUpdates for South Africa: +4406 cases, +65 deaths, +27875 tests since 21 hours ago — Italy: +75995 cases, +166 deaths, +446180 tests since a day ago21:05
BrainstormNew from CIDRAP: AstraZeneca's Evusheld slashes risk of symptomatic COVID-19 up to 83%: Mary Van Beusekom | News Writer | CIDRAP News Apr 21, 2022 Over 73% of participants were at elevated risk of infection owing to risk factors. → https://www.cidrap.umn.edu/news-perspective/2022/04/astrazenecas-evusheld-slashes-risk-symptomatic-covid-19-8321:58
BrainstormUpdates for France: +104007 cases, +185 deaths since 23 hours ago22:01
BrainstormNew from StatNews: Listen: An ominous biotech deal, vaccines for kids, & ‘breakthrough’ devices: On the latest episode of The Readout LOUD: Can biotech buyouts be bad news? Why can't Novavax meet a deadline? And what does "breakthrough" actually mean? Listen now: → https://www.statnews.com/2022/04/21/an-ominous-biotech-deal-vaccines-for-kids-breakthrough-devices/22:08
TurboTechGood afternoon gents.22:35
BrainstormNew from ##covid-19 Zotero group: Myocardial Injury Pattern at MRI in COVID-19                     Vaccine–associated Myocarditis: Type Journal Article Author Matteo Fronza Author Paaladinesh Thavendiranathan Author Victor Chan Author Gauri                             Rani Karur Author Jacob                         [... want %more?] → https://www.zotero.org/groups/covid_links/items/5S7PKZIB22:37
BrainstormNew from COVID on Twitter: Dr Emma Hodcroft (@firefoxx66): We unfortunately don't have fancy zoom-plotting in CoVariants.org (let us know if you'd like to help implement!), but you can fake-zoom-in by de-selecting the variants with the largest peaks (usually Omicron).See how the view changes with & without [... want %more?] → https://twitter.com/firefoxx66/status/151724513642565222722:56
TurboTechquiet room what happened?22:59
LjLwars23:00
LjLand covid fatigue23:00
TurboTechI wish I could claim Covid fatigue23:00
LjL##coronavirus has a bit more activity right at this time23:01
dTalmakes a change23:02
BrainstormNew from CIDRAP: Global COVID cases drop as pandemic disrupts routine US kids' vaccines: Lisa Schnirring | News Editor | CIDRAP News Apr 21, 2022 This school year 35,000 more US kids were not protected against common diseases. → https://www.cidrap.umn.edu/news-perspective/2022/04/global-covid-cases-drop-pandemic-disrupts-routine-us-kids-vaccines23:16
TurboTechNew Data23:26
BrainstormNew from COVID on Twitter: Tom Wenseleers (@TWenseleers): @firefoxx66 @OurWorldInData @MoiraZuber @ivan_aksamentov Nice one! Could be worth using daily infections as estimated by IHME as well (also available at OWID). You can roughly map cases to infections using glm(Lag(infections_IHME, shift=7) ~ log(CASES) + [... want %more?] → https://twitter.com/TWenseleers/status/151725425439800115223:36
TurboTechForgot how to post a link23:36
BrainstormNew from COVID on Twitter: Tom Wenseleers (@TWenseleers): @firefoxx66 @OurWorldInData @MoiraZuber @ivan_aksamentov or slightly more accurately using glm(Lag(infections_IHME, shift=7) ~ log(CASES) + ns(POSITIVITY_RATIO, df=2) : ns(GROWTH_IN_POSITIVITY_RATIO, df=2), family=poisson, data=XX) or ~ log(CASES_SMOOTHED) [... want %more?] → https://twitter.com/TWenseleers/status/151725549456979968823:46
BrainstormNew from COVID on Twitter: Florian Krammer (@florian_krammer): First of many papers from an effort led by @fred_hirsch, Adolfo García-Sastre, @acmoorephd and colleagues to track SARS-CoV-2 immunity in lung cancer patients. Lung cancer patients were especially hard hit by COVID-19.sciencedirect.com/science/articl… → https://twitter.com/florian_krammer/status/151726011784624128423:55

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