libera/##covid-19/ Tuesday, 2022-08-02

BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): Characterization of the BA.2.75 variantbiorxiv.org/content/10.110…—not more immune evasive than BA.5—modest resistance to bebtelovimab —higher receptor binding affinity (w/ 2 novel mutations) than other Omicron subvariants—unclear if it can compete [... want %more?] → https://twitter.com/EricTopol/status/155422341156761190500:02
BrainstormUpdates for Netherlands: +7327 cases, +5 deaths since 3 days ago — France: +80062 cases, +196 deaths since 3 days ago — Canada: +962 cases since 23 hours ago00:08
BrainstormNew from COVID on Twitter: Leana Wen, M.D. (@DrLeanaWen): The more cases of monkeypox, the harder it is to contain. The initial problem was lack of testing. If every case was identified, contacts could be traced and vaccinated to stop chains of transmission. Now, we have to vaccinate a much larger group—all those [... want %more?] → https://twitter.com/DrLeanaWen/status/155422598166099558500:11
BrainstormNew from COVID on Twitter: Tom Wenseleers (@TWenseleers): @EricTopol Should BA.2.75 not be treated at least on a par with BA.5 anyway? → https://twitter.com/TWenseleers/status/155422827762729779500:21
BrainstormNew from Novavax: (news): Novavax Statement on U.S. Vaccinations with the Novavax COVID-19 Vaccine, Adjuvanted Underway → https://ir.novavax.com/Novavax-Statement-on-U-S-Vaccinations-with-the-Novavax-COVID-19-Vaccine,-Adjuvanted-Underway00:30
BrainstormNew from COVID on Twitter: Tom Wenseleers (@TWenseleers): PS Here also Muller plot of lineage frequencies in India (raw GISAID data). BA.2.75 definitely outcompeting both regular BA.2 and BA.5 there... pic.twitter.com/3o7DjccWDc → https://twitter.com/TWenseleers/status/155423827215451750400:58
BrainstormUpdates for Algeria: +92 cases since a day ago01:05
BrainstormUpdates for Bulgaria: +3089 cases, +27 deaths, +12106 tests since 2 days ago — Syria: +78 cases since 3 days ago02:10
BrainstormNew from Reddit (test): It finally got me: . 2 and a half years I've avoided it. Dad tested positive yesterday and he's full of cold symptoms. → https://old.reddit.com/r/CoronavirusUK/comments/wdvq1p/it_finally_got_me/02:41
LjL%print https://arstechnica.com/science/2022/08/ny-county-with-polio-has-pitiful-60-vaccination-rate-1000s-may-be-infected/02:55
BrainstormLjL, It says: NY county with polio has pitiful 60% vaccination rate; 1,000s may be infected | Ars Technica02:55
LjLwhat the fuck02:55
LjLde-facto, pwr22 ↑↑ have you seen?03:10
pwr22Oof Israeli polio vaccine turned pathogen again?03:15
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): The "immunity wall" of a population to Covid outcomes is a function of many factors that include demographics, prior infections, and vaccinations. How does this concept help explain inter-country differences?erictopol.substack.com/p/immunity-wal… pic.twitter.com/K6KP6aWX7P → https://twitter.com/EricTopol/status/155427457091117465603:19
LjLpwr22, no, seems like people not getting vaccinated03:21
LjLalthough yeah the attenuated vaccine sporadically turns pathogen again03:21
pwr22It says it's derived from the oral vaccine which is only used in Israel though03:22
pwr22And now spreading around internationally03:23
LjLwhere does it say it's only used in israel?03:24
LjLall of the developing world uses the attenuated vaccine03:24
LjL<pwr22> And now spreading around internationally ← i'd say let's not blame a perfectly good attenuated vaccine that has nearly eradicated it worldwide (or israel) for a demented county in NY having a 60% vaccination rate because they're dumb anti-vax03:25
pwr22The bit about oral vaccine03:28
pwr22Lack of vaccination is definitely letting it run wild though03:29
pwr22"To be clear, vaccine-derived poliovirus strains evolve from oral polio vaccines (OPV), which are no longer used in the US or the UK. (Isreal uses both IPV and OPV.) The oral polio vaccines use weakened viruses that, if able to spread from person to person amid poor sanitation and low vaccination rates, can mutate to regain disease-causing capabilities. It's unclear where and how this VDPV2 originated and spread."03:30
LjLthat definitely doesn't say it's *only* used in Israel03:30
LjLand i know it's used pretty much anywhere the inactivated vaccine is "impractical" to deploy03:31
pwr22It has been detected in UK, US and Israel. It's derived from a vaccine used only in Israel among these. So... Smoking gun inference 😛03:31
pwr22In any case, it's pretty concerning it's in at least 3 countries03:32
LjLpwr22, that's pretty much like saying that the presence of a BSL4 lab in Wuhan and then COVID in the same Wuhan is smoking gun inference it's a lab leak03:35
LjLso i'm glad you agree that it's a lab leak!03:35
pwr22I don't think it's quite the same as that 🤣03:56
BrainstormUpdates for Canada: +29 cases since 3 hours ago04:03
BrainstormUpdates for South Korea: +111700 cases, +16 deaths since a day ago06:02
BrainstormNew from r/Science: science: Breastfeeding mothers produce antibodies to “Covid-19” that are able to neutralize the virus → https://old.reddit.com/r/science/comments/we1fus/breastfeeding_mothers_produce_antibodies_to/06:26
BrainstormUpdates for Germany: +102698 cases, +171 deaths since 22 hours ago07:04
BrainstormUpdates for Texas, United States: +28699 cases, +77 deaths since 2 days ago — New York, United States: +15965 cases, +52 deaths since 23 hours ago — Kanagawa, Japan: +14407 cases, +5 deaths since 23 hours ago — Virginia, United States: +7424 cases, +20 deaths since 2 days ago08:00
BrainstormNew from r/Science: science: Life expectancy drops for Native Americans due to COVID-19. The pandemic reduced Native American life expectancy at birth from the already low 72 years in 2019 to about 67 years in 2020 and about 65 years in 2021 for both sexes combined. → https://old.reddit.com/r/science/comments/we3e6d/life_expectancy_drops_for_native_americans_due_to/08:36
BrainstormNew from r/Coronavirus: Daily Discussion Thread | August 02, 2022: Please refer to our Wiki for more information on COVID-19 and our sub. You can find answers to frequently asked questions in our FAQ , where there is valuable information such as our: → https://old.reddit.com/r/Coronavirus/comments/we4s7g/daily_discussion_thread_august_02_2022/09:04
BrainstormNew from EMA: What's new: Medicine: Human medicines European public assessment report (EPAR): Fluad Tetra, influenza vaccine (surface antigen, inactivated, adjuvanted), Influenza, Human, Date of authorisation: 20/05/2020, Revision: 4, Status: Authorised → https://www.ema.europa.eu/en/medicines/human/EPAR/fluad-tetra09:41
BrainstormNew from COVID on Twitter: (translated) Marc Veldhoen (@Marc_Veld): Gert-Jan thinks he is funny; he makes us all laugh. Gert-Jan shows that he does not know that an immune response gains strength with multiple stimulations, 3x vaccinations provide very good protection against disease, infection is something else, and [... want %more?] → https://twitter.com/Marc_Veld/status/155437770662789120010:09
BrainstormUpdates for Czechia: +3446 cases, +23 deaths, +13007 tests since a day ago — Laos: +104 cases since a day ago10:11
BrainstormNew from r/COVID19: COVID19: Prevalence of peripheral neuropathy and myopathy in patients post-COVID-19 infection → https://old.reddit.com/r/COVID19/comments/we63ei/prevalence_of_peripheral_neuropathy_and_myopathy/10:47
BrainstormNew from Reddit (test): Covid2019: Covid Patients Should Take An Antiviral Even If They Don't Have Severe Symptoms, Study Finds → https://old.reddit.com/r/Covid2019/comments/we6jsn/covid_patients_should_take_an_antiviral_even_if/10:57
BrainstormUpdates for San Luis Potosi, Mexico: +2626 cases, +7 deaths since 3 days ago — Puebla, Mexico: +2117 cases, +8 deaths since 3 days ago — Chihuahua, Mexico: +1823 cases, +8 deaths since 3 days ago — Oaxaca, Mexico: +1464 cases, +7 deaths since 3 days ago11:01
BrainstormUpdates for Poland: +5645 cases, +22 deaths since 23 hours ago12:03
BrainstormNew from BMJ: “Downgrade your mask before entering”—a dangerous NHS policy at a critical public health ȷuncture: In May 2022, the UK Health Security Agency changed its guidance to make masking in healthcare settings a provider decision dependent on local risk assessment and prevalence.1 Local masking policies vary [... want %more?] → http://www.bmj.com/content/378/bmj.o1929.short12:13
BrainstormNew from EMA: Human medicine assessment reports: (news): Human medicines European public assessment report (EPAR): COVID-19 Vaccine (inactivated, adjuvanted) Valneva, COVID-19 vaccine (inactivated, adjuvanted, adsorbed), COVID-19 virus infection, Date of authorisation: [... want %more?] → https://www.ema.europa.eu/en/medicines/human/EPAR/covid-19-vaccine-inactivated-adjuvanted-valneva12:22
BrainstormUpdates for Romania: +11696 cases, +38 deaths since 22 hours ago — Estonia: +4659 cases, +8 deaths, +30536 tests since 6 days ago13:06
BrainstormUpdates for Slovenia: +2676 cases, +2 deaths since 23 hours ago — Afghanistan: +190 cases, +972 tests since a day ago14:08
BrainstormNew from Reddit (test): nCoV: Global COVID Cases For 02AUG22 → https://old.reddit.com/r/nCoV/comments/wea1y2/global_covid_cases_for_02aug22/14:14
BrainstormNew from COVID19 Vaccine Tracker: valerie: Adimmune Corporation: AdimrSC-2f → https://covid19.trackvaccines.org/vaccines/63/14:24
BrainstormNew from r/COVID19: COVID19: SARS-CoV-2-specific CD4+ and CD8+ T cell responses can originate from cross-reactive CMV-specific T cells → https://old.reddit.com/r/COVID19/comments/weafoi/sarscov2specific_cd4_and_cd8_t_cell_responses_can/14:34
BrainstormNew from Reddit (test): CoronaVirus_2019_nCoV: Vaccination cuts risk for myocardial infarction, stroke after COVID-19 → https://old.reddit.com/r/CoronaVirus_2019_nCoV/comments/weaoqg/vaccination_cuts_risk_for_myocardial_infarction/14:43
BrainstormNew from Reddit (test): CoronaVirus_2019_nCoV: A Live Recombinant Newcastle Disease Virus-vectored COVID-19 Vaccine Phase 1 Study. - Full Text View - ClinicalTrials.gov → https://old.reddit.com/r/CoronaVirus_2019_nCoV/comments/weatyj/a_live_recombinant_newcastle_disease/14:53
BrainstormUpdates for Iran: +9350 cases, +74 deaths since a day ago — Vietnam: +2017 cases, +1 deaths since a day ago — Bosnia and Herz.: +641 cases, +6 deaths, +1663 tests since a day ago15:10
BrainstormNew from COVID on Twitter: Josiah Grindrod is doing personal risk assessment (@JT_Grindrod): 2nd pandemic in a row where we ignore other nations to blaze our own trail and shit goes horribly wrong. China gave us the blueprint to beat SARS-COV-2, we ignored it, now there's millions dead and disabled.Our public [... want %more?] → https://twitter.com/JT_Grindrod/status/155445346089605529815:11
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): Cardiovascular disease after Covid, a new @Nature feature nature.com/articles/d4158… by @saimamaysidik pic.twitter.com/zHUAN20oB0 → https://twitter.com/EricTopol/status/155446183120839884915:50
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): The first study to use microneedle patch blood collection of antibodies to #SARSCoV2 (via remote, site-less, home collection) shows higher levels induced for 3 shots of Moderna (N=378) vs Pfizer (N=476) vaccines for all variants including Omicron [... want %more?] → https://twitter.com/EricTopol/status/155446579519095603515:59
BrainstormUpdates for Azerbaijan: +531 cases, +4 deaths since 23 hours ago16:00
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): This is the sad state-of-the science for #LongCovid drug treatments. A *41 patient* trial press release vs truthFailed primary endpointendpts.com/exclusive-in-p… @endptsPress release businesswire.com/news/home/2022… pic.twitter.com/qJ1gToDYv2 → https://twitter.com/EricTopol/status/155446855270677299616:09
BrainstormUpdates for Montenegro: +1053 cases, +1 deaths, +2659 tests since a day ago17:06
BrainstormNew from ClinicalTrials.gov: (news): Immunological Safety and Effectiveness of the First Booster Dose of mRNA Vaccines in Kidney Transplant Recipients. → https://clinicaltrials.gov/ct2/show/NCT0548372517:09
BrainstormNew from ClinicalTrials.gov: (news): Digital Health Intervention Based on Artificial Intelligence to Support the Personalized Recovery of Long COVID Patients Affected by Fatigue (AIDA) → https://clinicaltrials.gov/ct2/show/NCT0548382917:18
BrainstormNew from ClinicalTrials.gov: (news): Genomics, Environmental Factors and Social Determinants of Cardiovascular Disease in African-Americans Study (GENE-FORECAST): Prospective COVID-19 Natural History Study → https://clinicaltrials.gov/ct2/show/NCT0548488217:38
BrainstormNew from ClinicalTrials.gov: (news): Clinical Study of F61 Injection in Healthy Chinese Subjects → https://clinicaltrials.gov/ct2/show/NCT0548350417:57
BrainstormNew from ClinicalTrials.gov: (news): Antibodies and Immunity After Vaccination of Recovered Patients With COVID-19 and Long COVID-19 Symptoms → https://clinicaltrials.gov/ct2/show/NCT0548470018:25
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): How to reduce chance of a Covid hospitalization by 78% across all ages 18+?Get a booster.New @CDCgov datacovid.cdc.gov/covid-data-tra… pic.twitter.com/jYM9Q7MJMR → https://twitter.com/EricTopol/status/155450315482527744018:35
BrainstormNew from r/Coronavirus: Coronavirus: Heart disease after COVID: what the data say → https://old.reddit.com/r/Coronavirus/comments/weg755/heart_disease_after_covid_what_the_data_say/18:53
BrainstormNew from Contagion Live: Pandemic Prompts CDC to Strengthen Antibiotic Stewardship and Infection Prevention Programs: Finding that the COVID-19 pandemic disrupted best antibiotic practices, the CDC announced further efforts to curb [... want %more?] → https://www.contagionlive.com/view/pandemic-prompts-cdc-to-strengthen-antibiotic-stewardship-and-infection-prevention-programs19:12
BrainstormNew from WebMD: Haven't Had COVID Yet? Wanna Bet?: A mounting pile of scientific evidence suggests millions of Americans have been infected with the virus without ever even knowing it because they didn’t have symptoms or had mild cases they mistook for a cold or allergies. → https://www.webmd.com/lung/news/20220802/havent-had-covid-yet-wanna-bet20:00
BrainstormUpdates for Italy: +65099 cases, +190 deaths, +354431 tests since a day ago20:08
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): Coenzyme Q10 for #LongCovid?A randomized,  placebo-controlled, crossover design trial in 120 people did not demonstrate any benefitpapers.ssrn.com/sol3/papers.cf… pic.twitter.com/r5EfVsk87E → https://twitter.com/EricTopol/status/155453584856925388820:38
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): In the US, BA.5 now accounts for ~86% of new casescovid.cdc.gov/covid-data-tra…The only other variant increasing (a low level) is BA.4.6. Its mutation map (spike below) does not appear to be concerning cf BA.4/5 outbreak.info pic.twitter.com/AiAX8bgiPs → https://twitter.com/EricTopol/status/155455350611930726421:53
BrainstormUpdates for Serbia: +6936 cases, +10 deaths, +18856 tests since a day ago — Malaysia: +4204 cases, +8 deaths, +35674 tests since a day ago — Israel: +3702 cases, +8 deaths since a day ago — Spain: +13209 cases since 4 days ago22:01
BrainstormNew from Virology.ws: Trial By Error: A Few Things I’ve Read (or Heard) Lately About ME/CFS and Long Covid: By David Tuller, DrPH Here are a few things I’ve recently read (or listened to). FreakonomicsMD podcast The Freakonomics brand is well-known in [... want %more?] → https://www.virology.ws/2022/08/02/trial-by-error-a-few-things-ive-read-or-heard-lately-about-me-cfs-and-long-covid/22:03
BrainstormNew from CIDRAP: Survey: A third of US kids had excessive screen time amid COVID: Mary Van Beusekom | News Writer | CIDRAP News Aug 02, 2022 A total of 33% of young kids and 39% of those 11 to 17 had high Problematic Media Use Measure scores. → https://www.cidrap.umn.edu/news-perspective/2022/08/survey-third-us-kids-had-excessive-screen-time-amid-covid22:12
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): The fatality rate during Australia's BA.5 wave may be starting to decline, but no sign of that yet for Japan. Both countries contained the virus well for the first 2 years of the pandemicWhy do countries respond so differently to the same [... want %more?] → https://twitter.com/EricTopol/status/155456085859162112022:22
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): A clinical correlation for the above finding: impact of Moderna or Pfizer booster shots (after 2 shots Pfizer or Astra-Zeneca) to reduce infections and hospitalizations twitter.com/EricTopol/stat… → https://twitter.com/EricTopol/status/155456865934280704122:50
BrainstormNew from COVID on Twitter: Marc Veldhoen (@Marc_Veld): CAF08 adjuvant enables single dose protection against respiratory syncytial virus infection in murine newbornsProgress with a RSV vaccine. Strong protection with one shot in newborn mice.nature.com/articles/s4146… → https://twitter.com/Marc_Veld/status/155457564129044480223:19

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