libera/##covid-19/ Wednesday, 2022-09-14

BrainstormUpdates for India: +5188 cases since 23 hours ago — Guatemala: +1359 cases, +5 deaths since 23 hours ago — Bahrain: +318 cases, +3387 tests since 23 hours ago00:02
BrainstormNew from r/Coronavirus: Coronavirus: San Antonio Metro Health offering $100 H-E-B gift cards for all Covid vaccinations/boosters → https://old.reddit.com/r/Coronavirus/comments/xdjxnu/san_antonio_metro_health_offering_100_heb_gift/00:35
BrainstormNew from Reddit (test): nCoV: There's a new Covid variant spreading called omicron BA.4.6 | 13SEP22 → https://old.reddit.com/r/nCoV/comments/xdl6vn/theres_a_new_covid_variant_spreading_called/00:55
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): The toll of #LongCovid in Europe healthdata.org/news-release/w… @IHME_UW @WHO_Europe pic.twitter.com/8Qhci5xAyg → https://twitter.com/EricTopol/status/156982512057493504001:14
BrainstormNew from Contagion Live: CDC: US is Country With Circulating Vaccine-Derived Polio: The declaration not only puts the country on a list of countries circulating the viruses, but  it also means polio continues to be transmitted in Rockland County, NY, and surrounding areas. → https://www.contagionlive.com/view/cdc-us-is-country-with-circulating-vaccine-derived-polio01:42
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): Taiwan had over 47,000 new cases today and currently has the highest case per capita rate worldwide.That isn't high in absolute terms compared to its major wave but would be good to see new sequencing data@OurWorldInData and covariants.org pic.twitter.com/xRKLtT44nB → https://twitter.com/EricTopol/status/156983512838140723201:51
BrainstormNew from COVID on Twitter: Bloom Lab (@jbloom_lab): Caveat is obviously these results are all in mice.Nonetheless, it's interesting study that addresses  important questions, and seems to suggest current BA.5 bivalent booster is good choice & would probably be better than current vaccine as primary series too (if [... want %more?] → https://twitter.com/jbloom_lab/status/156983776130960179302:01
BrainstormNew from COVID on Twitter: Bloom Lab (@jbloom_lab): Minor note for aficionados: Fig 1 shows better monovalent titers against BA.1 / BA.5 relative to Wuhan-Hu-1 in lentiviral (using 293T-ACE2 cells) but not VSV pseudotype (using Vero-E6 cells).I wonder if this has to do with target cell ACE2 expression? twitter.com/jbloom_lab/sta… → https://twitter.com/jbloom_lab/status/156983776298730291202:10
BrainstormNew from Science Daily: Current vaccine approach not enough to eradicate measles: Current vaccination strategies are unlikely to eliminate measles, according to a new study. The paper explores the feasibility of eliminating measles and rubella using predominant vaccination strategies in 93 countries with the [... want %more?] → https://www.sciencedaily.com/releases/2022/09/220913201638.htm02:48
BrainstormUpdates for Canada: +3471 cases since 22 hours ago03:02
BrainstormNew from COVID on Twitter: Bloom Lab (@jbloom_lab): Actually, ignore this last Tweet. It's more likely difference between Wuhan-Hu-1 + D614G versus just D614G. → https://twitter.com/jbloom_lab/status/156985674740967014403:16
BrainstormNew from COVID on Twitter: Michael Lin, MD PhD   (@michaelzlin): The US has used the Salk-style inactivated polio vaccine (IPV) since 2000 for safety. Ironically its lower efficacy against transmission, combined with low vax rates in some places, is now allowing poliovirus vax strain brought in from abroad to [... want %more?] → https://twitter.com/michaelzlin/status/156986088906656973003:35
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): The Moderna bivalent BA.1 booster vaccine had similar results as the bivalent BA.5 vaccine vs. BA.5 in the mouse model for induced level of neutralizing antibody, reduced viral load and inflammatory response in the lungbiorxiv.org/content/10.110… pic.twitter.com/4nAKk5HuvS → https://twitter.com/EricTopol/status/156987027547871232104:14
BrainstormUpdates for Thailand: +1321 cases, +14 deaths since 23 hours ago — Germany: +51299 cases, +100 deaths since 23 hours ago05:07
BrainstormNew from COVID on Twitter: Tulio de Oliveira (@Tuliodna): Found a Nature piece, 25 Feb 2020 on our team was one of the firstto respond to the pandemic & develop genomics systems by 2 Feb 2020. Fun to go back in time. Lots of Interesting info on the early story of the pandemic response. nature.com/nature-index/n… → https://twitter.com/Tuliodna/status/156988828597109145705:30
BrainstormNew from COVID on Twitter: Michael Lin, MD PhD   (@michaelzlin): Interesting parallels between polio and SARSCoV2, with respect to how the herd immunity threshold depends on exposure risk, which is influenced by both the environment and vaccines themselvestypefully.com/famulare_mike/… → https://twitter.com/michaelzlin/status/156991209280704102606:55
BrainstormUpdates for South Korea: +93904 cases, +60 deaths since a day ago — Switzerland: +13816 cases since 13 hours ago — Laos: +93 cases since 21 hours ago06:59
BrainstormUpdates for Nauru: +4608 cases, +1 deaths since 5 months ago — Osaka, Japan: +9617 cases, +19 deaths since 23 hours ago — Bavaria, Germany: +9047 cases, +16 deaths since 23 hours ago — Aichi, Japan: +8757 cases, +13 deaths since 23 hours ago08:01
BrainstormNew from Reddit (test): CoronaVirus_2019_nCoV: Boston Children’s researchers find antibody effective against all known COVID variants in lab tests → https://old.reddit.com/r/CoronaVirus_2019_nCoV/comments/xduj2f/boston_childrens_researchers_find_antibody/08:39
BrainstormNew from COVID on Twitter: Marc Veldhoen (@Marc_Veld): Bivalent SARS-CoV-2 mRNA vaccines increase breadth of neutralization and protect against the BA.5 Omicron variantBevallen vaccine gives broader neutralising antibodies used as primary and also as booster, protects against BA.5 (mice). biorxiv.org/content/10.110… → https://twitter.com/Marc_Veld/status/156994137702203392008:58
BrainstormNew from r/Coronavirus: Daily Discussion Thread | September 14, 2022: Please refer to our Wiki for more information on COVID-19 and our sub. You can find answers to frequently asked questions in our FAQ , where there is valuable information such as our: → https://old.reddit.com/r/Coronavirus/comments/xdv03y/daily_discussion_thread_september_14_2022/09:08
BrainstormNew from EMA: Human medicine assessment reports: (news): Human medicines European public assessment report (EPAR): Spikevax (previously COVID-19 Vaccine Moderna), elasomeran,imelasomeran and elasomeran,COVID-19 mRNA vaccine (nucleoside-modified), COVID-19 virus infection, Date of authorisation: 06/01/2021, [... want %more?] → https://www.ema.europa.eu/en/medicines/human/EPAR/spikevax09:36
BrainstormUpdates for Taiwan: +49660 cases, +37 deaths, +70687 tests since 23 hours ago10:05
BrainstormNew from StatNews: Complexity of Covid vaccine program leads to concerns about potential for error: The rollout of the Covid-19 vaccination program has reached new heights of complexity with the start of the bivalent booster program, leading to concerns [... want %more?] → https://www.statnews.com/2022/09/14/complexity-of-covid-vaccine-program-leads-to-concerns-about-potential-for-error/10:52
BrainstormNew from StatNews: Opinion: A challenge trial can streamline testing of hepatitis C vaccines: With a cure for #hepatitisC in hand, now is the time to use challenge trials to test new vaccines to prevent this debilitating and even deadly disease. → https://www.statnews.com/2022/09/14/a-challenge-trial-can-streamline-testing-of-hepatitis-c-vaccines/11:02
BrainstormNew from ProPublica: For Helping Voters Who Can’t Read, She’s Been Criminally Charged — Twice. That Hasn’t Stopped Her.: by Mauricio Rodríguez Pons , Aliyya Swaby and Annie Waldman Sign up for ProPublica’s User’s Guide to Democracy , a series of personalized emails that help you [... want %more?] → https://www.propublica.org/article/voting-rights-video-georgia-literacy#143360911:11
BrainstormNew from Reddit (test): CoronavirusUK: Are You A COVID "Super-Dodger?" Then Scientists Want To Hear From You → https://old.reddit.com/r/CoronavirusUK/comments/xdxbmk/are_you_a_covid_superdodger_then_scientists_want/11:30
BrainstormNew from ProPublica: State Investigation Reveals Racial Disparities in Student Discipline and Police Involvement: by Jodi S. Cohen , ProPublica, and Jennifer Smith Richards ,  Chicago Tribune ProPublica is a nonprofit newsroom that [... want %more?] → https://www.propublica.org/article/state-investigation-reveals-racial-disparities-in-student-discipline-and-police-involvement#143424612:08
BrainstormUpdates for Russia: +51735 cases, +98 deaths since a day ago12:10
BrainstormNew from COVID on Twitter: Jeffrey Barrett (@jcbarret): Awesome thread from Charlotte. I was just thinking “I really need to read something about this vaccine derived polio infection, because I know nothing”. Five tweets later and I am no longer in the dark.   twitter.com/drcj_houldcrof… → https://twitter.com/jcbarret/status/156999423696293888512:27
BrainstormNew from EMA: What's new: Orphan: Orphan designation: Radio-iodinated (131I) anti-CD45 murine monoclonal antibody, Treatment in haematopoietic stem cell transplantation, 14/10/2016, Positive → https://www.ema.europa.eu/en/medicines/human/orphan-designations/eu-3-16-176012:36
BrainstormUpdates for UAE: +402 cases, +244532 tests since 21 hours ago12:59
BrainstormNew from r/COVID19: COVID19: Why it took so long to recognize airborne transmission of the coronavirus, and how to do better next time → https://old.reddit.com/r/COVID19/comments/xdyy1n/why_it_took_so_long_to_recognize_airborne/13:05
BrainstormNew from Science-Based Medicine: A New Malaria Vaccine: A second anti-malarial vaccine in just two years could be a game-changer for this deadly disease. The post  first appeared on Science-Based Medicine . → https://sciencebasedmedicine.org/a-new-malaria-vaccine/13:52
BrainstormNew from COVID on Twitter: Scott Gottlieb, MD (@ScottGottliebMD): Flu causes up to 710,000 hospitalizations; 52,000 deaths in U.S. each year. Continued drug, vaccine innovation is important to public health. “First Phase 3 efficacy study using an mRNA-based flu vaccine; will enroll 25,000 U.S. adults 18 years [... want %more?] → https://twitter.com/ScottGottliebMD/status/157002317888946995414:21
BrainstormNew from EMA: What's new: Event: EMA regular press briefing on COVID-19 and monkeypox, Online, 14:00 - 14:30 Amsterdam time (CEST), from 20/09/2022 to 20/09/2022 → https://www.ema.europa.eu/en/events/ema-regular-press-briefing-covid-19-monkeypox-014:42
BrainstormNew from r/Coronavirus: Coronavirus: ‘We are only beginning to know what it is’: Why doctors struggle to identify treatments for long COVID → https://old.reddit.com/r/Coronavirus/comments/xe13km/we_are_only_beginning_to_know_what_it_is_why/14:51
BrainstormUpdates for Indonesia: +2799 cases, +21 deaths, +74527 tests since 22 hours ago15:04
BrainstormNew from StatNews: Pharma: STAT+: Pharmalittle: Pharma pursues the ‘dream’ of online prescribing; EC chief under fire over Pfizer vaccine contract → https://www.statnews.com/pharmalot/2022/09/14/covid19-vaccine-pfizer-abortion-novartis-fda-hepatitis-prescribing/15:30
BrainstormUpdates for China: +8577 cases since 23 hours ago — Croatia: +1021 cases, +4 deaths, +4037 tests since 23 hours ago16:06
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): Extensive characterization of the BA.5 variant's features of enhanced immune escape, ability to spread, and pathogenicity cell.com/cell/fulltext/… New @CellCellPress by @SystemsVirology pic.twitter.com/UydMgy7Tmj → https://twitter.com/EricTopol/status/157005060755334758616:08
BrainstormNew from r/COVID19: COVID19: Dedicated team to ambulatory care for patients with COVID-19 requiring oxygen: Low rate of hospital readmission → https://old.reddit.com/r/COVID19/comments/xe34m8/dedicated_team_to_ambulatory_care_for_patients/16:19
BrainstormNew from Reddit (test): nCoV: Under COVID lockdown, Xinjiang residents complain of hunger | 14SEP22 → https://old.reddit.com/r/nCoV/comments/xe3m4q/under_covid_lockdown_xinjiang_residents_complain/16:38
BrainstormNew from EMA: What's new: General: COVID-19 vaccines: key facts → https://www.ema.europa.eu/en/human-regulatory/overview/public-health-threats/coronavirus-disease-covid-19/treatments-vaccines/vaccines-covid-19/covid-19-vaccines-key-facts16:48
BrainstormUpdates for Azerbaijan: +371 cases, +9 deaths since a day ago17:08
BrainstormNew from ClinicalTrials.gov: (news): Improving Mental Health Among the LGBTQ+ Community → https://clinicaltrials.gov/ct2/show/NCT0554006717:27
BrainstormNew from LitCovid: (news): Effect of SARS-CoV-2 Infection and Infection Severity on Longer-Term Glycemic Control and Weight in People With Type 2 Diabetes. → https://www.ncbi.nlm.nih.gov/research/coronavirus/publication/3609866017:46
BrainstormNew from LitCovid: (news): Phytochemicals of Cocculus hirsutus deciphered SARS-CoV-2 inhibition by targeting main proteases in molecular docking, simulation, and pharmacological analyses. → https://www.ncbi.nlm.nih.gov/research/coronavirus/publication/3609918218:05
BrainstormUpdates for Myanmar: +384 cases, +1 deaths since a day ago18:11
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): Good to see Covid optimism @WHO @DrTedros reuters.com/business/healt…But world deaths are currently 34% higher than the nadir reached in June (~20% are in the US).And the virus's evolutionary arc is incomplete pic.twitter.com/gzG3sCl0mw → https://twitter.com/EricTopol/status/157008316787237273618:15
BrainstormNew from COVID19 Vaccine Tracker: valerie: Altimmune Inc: AdCOVID → https://covid19.trackvaccines.org/vaccines/75/18:25
BrainstormNew from COVID19 Vaccine Tracker: valerie: AIM Vaccine: LVRNA009 → https://covid19.trackvaccines.org/vaccines/189/18:35
BrainstormNew from r/COVID19: COVID19: Invasive Pneumococcal Disease diminish during the onset of COVID-19 in Japan between 2019 and 2022 → https://old.reddit.com/r/COVID19/comments/xe7bec/invasive_pneumococcal_disease_diminish_during_the/19:13
BrainstormNew from r/Coronavirus: Coronavirus: WHO: COVID End 'In Sight,' Deaths at Lowest Since March 2020 → https://old.reddit.com/r/Coronavirus/comments/xe7x1b/who_covid_end_in_sight_deaths_at_lowest_since/20:02
BrainstormUpdates for Japan: +100229 cases, +184 deaths since 23 hours ago — Italy: +18849 cases, +69 deaths, +171457 tests since a day ago20:03
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): Think outside the spikeA vaccine directed against the spike and nucleocapsid proteins has broad, potent immune response vs Omicron in 2 different experimental modelsscience.org/doi/10.1126/sc… @ScienceTM → https://twitter.com/EricTopol/status/157011111715813376420:12
BrainstormNew from CIDRAP: News Scan for Sep 14, 2022: COVID boosters, antibodies in nursing homes US polio status Avian flu in US, Belize → https://www.cidrap.umn.edu/news-perspective/2022/09/news-scan-sep-14-202220:59
BrainstormNew from CIDRAP: Possible 69% higher risk of Alzheimer's for older COVID survivors: Mary Van Beusekom | News Writer | CIDRAP News Sep 14, 2022 Older COVID-19 survivors may be at a 69% higher risk of developing Alzheimer's within 1 year. → https://www.cidrap.umn.edu/news-perspective/2022/09/possible-69-higher-risk-alzheimers-older-covid-survivors21:38
BrainstormUpdates for Malaysia: +2431 cases, +5 deaths since a day ago — France: +29526 cases, +18 deaths since 23 hours ago22:07
BrainstormNew from ScienceNews: Poliovirus is spreading in New York. Here’s what you need to know: With signs of poliovirus spreading in a handful of counties in New York, unvaccinated people could be at risk of paralytic polio. → https://www.sciencenews.org/article/polio-cdc-spread-new-york-vaccine-virus22:07
BrainstormUpdates for India: +5559 cases since 23 hours ago23:03
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): Important @NEJM report on the protection rendered by high mucosal IgA vs Omicron, whether or not prior Covid, with 65% reduction of breakthrough infections, effect not related to high levels of IgG antibodies nejm.org/doi/full/10.10… pic.twitter.com/edivcDErVF → https://twitter.com/EricTopol/status/157015595899486208323:05
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): The impact of mucosal IgA was also seen for reduced viral replication. "These findings suggest that wild-type #SARSCoV2 spike-specific mucosal IgA is protective against omicron infection." → https://twitter.com/EricTopol/status/157015695169435238423:15
BrainstormNew from COVID on Twitter: Florian Krammer (@florian_krammer): This is a very important paper by the Thålin lab showing an association between mucosal IgA and protection from (Omicron) infection. I'll likely do a longer tweetorial about this on the weekend. twitter.com/NEJM/status/15… → https://twitter.com/florian_krammer/status/157016000264350925123:24
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): This is the 1st study to measure mucosal IgA (and IgG) in a large number of people and relate that to Omicron infections (which have not been reduced well by vaccines)It's yet another strong signal that getting our mucosal IgA level up high (yes, nasal vaccines) [... want %more?] → https://twitter.com/EricTopol/status/157016298944948224123:34
BrainstormNew from COVID on Twitter: Eric Topol (@EricTopol): Vaccine effectiveness vs BA.5 wave hospitalization in South Africa @Discovery_SA nejm.org/doi/full/10.10…It was 70% vs BA.1 severe disease with 2 doses.New report compares vs BA.1/2, 2 or 3 dosesTable and conclusion below pic.twitter.com/VdX1UakuUw → https://twitter.com/EricTopol/status/157016547799296000123:43

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