libera/##covid-19/ Wednesday, 2021-01-13

python476hi again LjL00:03
python476happy to know you're here in flesh and soul00:03
LjLpython476, no guarantees about the soul00:07
BrainstormNew from StatNews: U.S. plan to expand access to Covid-19 vaccine likely sets up new debacles: HHS Secretary Alex Azar's new instructions put about half of the adult population of the country at the front of the Covid-19 vaccine line. But the math doesn't work. → https://is.gd/fkMZrb00:12
LjLpython476, when do you reckon you'll get your shot, 2030-2040?00:13
de-factohttps://covidvax.org/ Germany 70% vaccinated with second dose in ... 00:15
de-facto...March 202700:15
de-factoLOL this is... :(00:15
de-factobut hey the world needs 10 years, so why am i complaining :/00:16
de-factook to be fair, speed did not ramp up yet but still its WAY too slow00:16
de-factolike orders of magnitude 00:17
de-factoCumulative COVID-19 vaccinations per 100 people00:23
de-factoIsrael: 22.20; United Arab Emirates: 12.90; Bahrain: 5.75; Northern Ireland: 5.25; England: 4.40; United Kingdom: 4.19; Scotland: 3.27; Wales: 2.90; United States: 2.82; Denmark: 2.02; Iceland: 1.43; Italy: 1.31; Slovenia: 1.08; Spain: 1.04;00:23
de-factoCanada: 0.95; Lithuania: 0.92; Estonia: 0.90; Germany: 0.82; Hungary: 0.81; Sweden: 0.78; Romania: 0.73; Croatia: 0.73; Ireland: 0.71; Portugal: 0.69; Cyprus: 0.69; Poland: 0.68; China: 0.63; Austria: 0.59; Slovakia: 0.58; Russia: 0.55; Greece: 0.54; Saudi Arabia: 0.51;00:23
de-factoLatvia: 0.44; Norway: 0.39; World: 0.37; Oman: 0.36; Finland: 0.32; Malta: 0.32; Luxembourg: 0.31; France: 0.29; Netherlands: 0.26; Argentina: 0.24; Bulgaria: 0.20; Costa Rica: 0.19; Czechia: 0.19; Serbia: 0.14; Mexico: 0.07; Belgium: 0.07; Chile: 0.06; Kuwait: 0.06; Guinea: 0.00;00:23
LjLthis is going to look like a big "win" for Brexit00:24
LjLeven if it's not really thanks to Brexit that they did it, doesn't really matter00:24
LjLpeople will correlate and causate00:24
BrainstormNew from Ars Technica: Science: Trump admin. adopts Biden’s vaccine plan, threatens to punish slow states → https://is.gd/s1L5sh00:24
python476LjL: I managed to get through the first waves, I don't even worry about when I'll have a shot00:37
python476plus I'm in the "let's wait and see how the vaccines perform" sad group00:37
python476how is it on your side of the alps ?00:37
python476brb, emacs pebcak failure 00:38
python476so00:48
LjLso fyi00:50
LjLour government is likely falling apart00:50
LjLso expect a gloriously fascist Italy next time00:51
LjLpython476, i think the vaccines perform fine unless it's astrazeneca, so i'd rather be on the pfizer train while it's around (but i won't be, and realistically neither will my parents)00:53
python476it's honestly challenging to follow what's going on in the world..00:54
python476I had no idea italy govt was crackig00:54
python476*ng00:54
LjLi'm not sure they all know, either00:55
LjLthey may find out in parliament00:55
de-factodamn that does not sound good at all01:00
BrainstormNew from Emma Hodcroft: @firefoxx66: R to @firefoxx66: To learn more about the new variant that was found in sequences from Japan (484K+501Y) earlier in the thread, be sure to check out this great post from @nmrfaria & @CaddeProject. This is a variant circulating in Manaus, [... want %more?] → https://is.gd/h7dNDj01:01
LjLde-facto, if you thought 2020 sucked...01:04
BrainstormUpdates for United Kingdom: +40972 cases (now 3.2 million), +1175 deaths (now 83203) since 17 hours ago01:05
CoronaBot04/r/covid19: COVID-19 reinfection in the presence of neutralizing antibodies (80 votes) | https://academic.oup.com/nsr/advance-article/doi/10.1093/nsr/nwab006/6081102 | https://redd.it/kvzr2p01:07
LjLagain about this though  New from r/WorldNews: worldnews: CoronaVac’s Overall Efficacy in Brazil Measured at 50.4% → https://is.gd/PtwNlV01:07
LjLi mean sure, at first the agencies didn't know what sort of efficacy a vaccine might have, so they set 50% as a bare minimum threshold01:08
LjLbut surely if herd immunity is around 70% then a vaccine that prevents 50% isn't exactly stellar?01:08
LjL(also 50.4% come on, it could have been 49.8% if they just massaged the numbers a little differently)01:09
python476on that note I have to go01:10
python476or ill be late for charity again01:10
python476see ljl01:10
python476take care01:10
LjLaw01:11
python476and take over italy if needs be01:11
python476the world needs more ljls01:11
python476:p01:11
LjL'night01:11
BrainstormNew from NPR: CDC Requires COVID-19 Test From Air Passengers Entering the U.S.: Starting Jan. 26, airlines will only allow people to board if they  provide documentation that they tested negative in the preceding three days or have recovered from the disease. → https://is.gd/gN5lv901:13
BrainstormUpdates for Togo: +67 cases (now 4045) since a day ago — France: +6778 cases (now 2.8 million) since 23 hours ago — Canada: +6605 cases (now 675006), +115 deaths (now 17201) since 23 hours ago — Switzerland: +49 deaths (now 8470) since 9 hours ago01:24
rahmend[m]Yelp lets you report restaurants that aren't following COVID-19 rules (engadget.com)01:24
CoronaBot04/r/covid19: The chronic neuropsychiatric sequelae of COVID‐19: The need for a prospective study of viral impact on brain functioning (80 votes) | https://alz-journals.onlinelibrary.wiley.com/doi/10.1002/alz.12255 | https://redd.it/kuyy1o01:31
BrainstormNew from Ars Technica: Tech: Razer’s N95: Voice boost, active ventilators, LED lights in mask prototype → https://is.gd/64vqcq01:50
LjLlol01:53
DocScrutinizer05maybe I should really start designing my silly very special variant of protective gear against virus01:59
BrainstormNew from BBC Health: (news): Covid: Many NHS staff 'traumatised' by first wave of virus, study shows → https://is.gd/swSDWM02:03
LjLugh02:08
LjLthe above government communication states how the money (from the EU? not sure, anyway, lots of money, 210 billion) is going to be used for "recovery"02:09
LjLin particular look at this graph http://www.governo.it/sites/new.governo.it/files/immagini_content/img.png02:09
LjLthe highest bar is about ecology and "green revolution", and i'm kind of okay with that one, i guess02:09
LjLsecond one "digitalization and blah blah" i'm already not so okay, especially considering that, yes, it says "culture", but there is a separate (and much lower) "Education and research" section02:10
LjLbut the LAST one is "Health"02:10
LjLare they literally kidding me?02:10
BrainstormUpdates for Germany: +14402 cases (now 2.0 million), +1106 deaths (now 43203) since 13 hours ago02:57
P1gassuLjL, will they be able to determine if the vaccines prevent asymptomatic spread ? if so when03:05
LjLP1gassu, when enough people have been vaccinated for the effect of that to be observable03:06
LjLi don't think there is an ethical way to do it otherwise03:07
LjLyou can check it on animals, but nothing guarantees it'll be the same in humans03:07
LjLor you could be the UK and run human challenge studies, i suppose03:07
LjLwhich i find quite unethical, but i am no nation's prime minister03:07
P1gassuLjL, so at some point, there might be contact tracing back to a person who was vaccinated, vs. there being studies03:08
LjLP1gassu, something like that could happen, but unless you get several such instances, it'll still be hard to attribute with certainty... i think it's more likely they will look at the epidemic dynamics, and determine whether it's more compatible with lingering asymptomatic spread, or actual herd immunity03:10
LjLde-facto, DocScrutinizer05: uhm... a good point? https://old.reddit.com/r/worldnews/comments/kw62kl/scientists_fear_the_escape_mutant_in_coronavirus/gj2hs8m/?context=303:14
BrainstormNew from r/WorldNews: worldnews: Scientists fear the 'escape mutant' in coronavirus variant from South Africa → https://is.gd/KOvoAa03:15
de-factoaaw gawd i HATE websites that autoplay video on visit03:16
LjLde-facto, you can block it on Firefox!03:17
de-facto.title https://virological.org/t/spike-e484k-mutation-in-the-first-sars-cov-2-reinfection-case-confirmed-in-brazil-2020/58403:18
Brainstormde-facto: From virological.org: Spike E484K mutation in the first SARS-CoV-2 reinfection case confirmed in Brazil, 2020 - nCoV-2019 Genomic Epidemiology - Virological03:18
LjLanyway i was referring to the particular highlighted comment as a potentially good point, not the article :P03:18
de-factooh lol for redit links i always click on the article and never read the comments, i should change that!03:19
de-factohmm do the timelines for spread of E484K and CoronaVac phase III trial data overlap?03:20
LjL%vax coronavac brazil03:21
BrainstormLjL, no such vaccine found. Try checking https://covidvax.org 03:21
LjL%vax coronavac brasil03:21
BrainstormLjL, no such vaccine found. Try checking https://covidvax.org 03:21
LjLbooooring03:21
LjL%vax coronavac03:21
BrainstormLjL, no such vaccine found. Try checking https://covidvax.org 03:21
LjLis it working at all03:21
LjL%vax moderna03:21
BrainstormLjL, mRNA-1273 LNPencapsulated mRNA is a RNA-based vaccine developed in USA by Moderna + NIAID + Lonza + Catalent Inc. + BIOQUAL, which began its distribution on date January 2021 with  participants → https://covidvax.org/covid19-vaccine/Moderna03:21
LjLsinovac is coronavac, right?03:22
de-factoLjL, btw that raises an interesting question: do they have samples for all their phase III trial participants in the vaccination arm that got infections? id guess they do, so why not sequence those?03:22
de-factoyep03:22
LjLit says phase 3 in brazil started July 2 202003:22
LjLthat probably predates any known occurrence of E484K? but let's check03:22
de-factoid think it was first recognized in SA03:23
LjLyes, afaik03:23
LjLde-facto, uhm, on Nextstrain, E484K is mostly found since October, but there are a couple rare occurrences in September03:24
de-factoi they could provide full sequences for all infections in vax trials maybe they could find some statistics about variants, e.g. compared to the placebo arm, where there significantly more of several variants in the verum arm?03:24
LjLbut not in Brazil03:24
de-factoyeah i think it only very recently spilled over to Brazil from SA, but i might be wrong03:25
LjLnot *very*03:26
LjLfirst Brazilian spotting is in early October03:26
LjLhttps://nextstrain.org/ncov/south-america?c=gt-S_484&s=Brazil/RJ-00541/202003:27
LjLthe phase 3 trial in Brazil is still recruiting, if i am to believe clinicaltrials.gov03:28
de-facto[m]Ok so prob not too much overlap with end of phase3 trials data taking?03:28
LjLso it's perhaps not too unlikely that it could have been affected by this mutation?03:28
de-facto[m]Oh really03:28
de-facto[m]If its that ptevalent yet?03:29
LjLhttps://clinicaltrials.gov/ct2/show/NCT0445659503:29
LjLi don't know if it's very prevalent, i think the article said it was, but it's just an article, also let me reread03:29
de-facto[m]how widespread is it in the study areas, how likely prevalent enough to occur with significance in the results?03:30
de-facto[m]Thats why id like to see sequences for infections in studies03:30
LjLhttps://www.medrxiv.org/content/10.1101/2020.12.23.20248598v1.full03:31
LjLthey had 180 samples here03:31
LjLout of those, "Cluster 1 was composed of 38 samples, predominantly from B.1.1.28 lineage, detected after early October"03:31
de-facto[m]Maybe there is bias for such variants if they could evade immunity like from the link from virological03:31
LjLand in those, "In addition to these five variants, we also found the substitution G23012A (E484K) in S protein across 36 out of the 38 samples in this group."03:31
LjLso that would make it a 20% prevalence03:32
LjLde-facto[m], well i guess it's in the best interest of companies making vaccines to sequence people who got the virus despite receiving the vaccine... so... hopefully they'll do it? it should be a great boost to their ability to continue making effective vaccines in the future03:35
de-facto[m]i very much hope so, this really has to be monitored now especially for  selection of variants in vaccinated infections vs unvaccinated infections in same area and time03:38
de-facto[m]Because if there is selection it means a new variant has to be included in a vaccine update03:39
CoronaBot04/r/covid19: Intranasal ChAdOx1 nCoV-19/AZD1222 vaccination reduces shedding of SARS-CoV-2 D614G in rhesus macaques (80 votes) | https://www.biorxiv.org/content/10.1101/2021.01.09.426058v1 | https://redd.it/kvp7bc03:44
de-factoLjL, so if you get offered an injection of AZD1222 ask if you can sniff it instead? :D04:02
LjL:D04:02
LjLseriously, though, i don't know if i'd want AZ... i've been pondering that without really being sure of what i'd do. i want to see more data that is not, de facto, cherry-picked post-factum ;)04:04
LjLbut at the same time, the side effect profile seems okay, so i wouldn't risk much by getting it, i guess04:05
LjLexcept... what if i get offered something else, like Pfizer, later? or even, what if people in general are offered something else, but if you already got AZ, you don't qualify?04:05
LjLwe don't know the side effects profile of mixing two different vaccines04:05
LjLand you were very much against doing that for the 1st and 2nd dose so you probably understand that there are many unknowns about that04:06
de-factoi cant really oppose to any of those statements04:07
de-factoyeah i think we should go with evidence based science, that does not mean that all those considerations discussed would not work, but i want them to be proven to work prior to wide scale deployment 04:08
de-factoi think right now i would not really decline a vaccine that is approved and offered to be given with that approved scheme04:09
de-factoi have not really seen data that would make me think it would be a bad idea to take vaccine XYZ04:10
de-factosure there are some differences, but right now imho time is the factor that makes the most difference04:10
de-factoso if i had the choice between right now AZ1222 or BNT162b2 in the summer id go with AD122204:11
BrainstormUpdates for Barbados: +84 cases (now 968) since a day ago — St. Vin. and Gren.: +31 cases (now 284) since 16 hours ago — Monaco: +22 cases (now 1092), +3 deaths (now 7) since a day ago — New Zealand: +6 cases (now 2228) since 2 days ago04:11
de-factoif i could wish for anything id like it wish for CureVac to show good trial results and to get that then04:11
de-factobut they just started with phase III afaik, so it will take quite some time04:12
de-factoimho the most important thing is to significantly ramp up production rates, we need orders of magnitude more vaccination rates04:12
de-factounrelated sidenote04:22
de-facto./title https://investors.biontech.de/news-releases/news-release-details/statement-voluntary-covid-19-vaccination-biontech-employees-and04:22
de-facto.title04:22
Brainstormde-facto: From www.medrxiv.org: Genomic characterization of a novel SARS-CoV-2 lineage from Rio de Janeiro, Brazil | medRxiv04:22
de-factountil now it was illegal for BioNTech employees to get vaccination just because they produce it04:23
de-factonow they found a way to offer it to their employees04:23
de-facto"To maintain the integrity of our supply chain, including the development, production, approval, supply and distribution of the vaccine, BioNTech has decided to offer a voluntary COVID-19 vaccination to its employees in Germany. In addition, the Company will make the vaccine available to suppliers and distribution partners in Germany and Austria who are actively and directly involved in the production and distribution process."04:23
de-factosystem relevant jobs... :)04:23
BrainstormNew from r/WorldNews: worldnews: U.S. Will Require Negative COVID-19 Results from All Incoming Travelers → https://is.gd/kvZzfQ04:28
de-factohow about quarantine or make airtravel completely illegal?04:29
de-factooh wait that would make the spread of new variants all over the world nearly impossible, we cant have that, can we?04:31
BrainstormNew from The Indian Express: World: Indonesia president launches Covid-19 inoculation drive with Chinese vaccine → https://is.gd/S7jl8c05:05
BrainstormNew from NPR: Stay-At-Home Order Lifted for Sacramento Region In California: Over 90% of Californians are still subject to the order, which went into effect in December. → https://is.gd/UmXVaE05:28
BrainstormNew from The Indian Express: World: New Brazil data shows disappointing 50.4% efficacy for China’s CoronaVac vaccine → https://is.gd/rUn94E05:53
CoronaBot04/r/coronavirus: The House has approved fines for members who don’t comply with a mask-wearing mandate (10714 votes) | https://www.theguardian.com/us-news/live/2021/jan/12/donald-trump-impeachment-insurrection-capitol-joe-biden-coronavirus-covid-live-updates?page=with:block-5ffe57e08f0853a2a9aaa6e8#block-5ffe57e08f0853a2a9aaa6e8 | https://redd.it/kw6uz106:03
BrainstormNew from EurekAlert!: Families' remote learning experience during lockdown more positive than widely believed: The remote learning experience of parents who had their children at home in Spring 2020, as schools across the US closed during the United States' COVID-19 lockdown, was more positive than widely believed. → https://is.gd/JITXT106:29
BrainstormNew from r/WorldNews: worldnews: Sinovac: Brazil results show Chinese vaccine 50.4% effective → https://is.gd/gpPSky06:41
zutt%cases sweden06:41
Brainstormzutt: In Sweden, there have been 506866 confirmed cases (4.9% of the population) and 9667 deaths (1.9% of cases) as of 15 hours ago. 4.7 million tests were performed (10.7% positive). See https://offloop.net/covid19/?default=Sweden for time series data.06:41
zutt10k deaths milestone coming up soon..06:42
BrainstormNew from r/WorldNews: worldnews: New Zealand jobs market bounces back - employment rate already back to near pre-pandemic levels → https://is.gd/WfeiaU06:53
BrainstormNew from BBC Health: (news): Covid: Many NHS staff 'traumatised' by first wave of virus, study shows → https://is.gd/swSDWM07:18
CoronaBot04/r/covid19: EMA receives application for conditional marketing authorisation of COVID-19 Vaccine AstraZeneca (80 votes) | https://www.ema.europa.eu/en/news/ema-receives-application-conditional-marketing-authorisation-covid-19-vaccine-astrazeneca | https://redd.it/kvnu4s07:22
BrainstormNew preprint: Convergence of Comorbidity and COVID-19 Infection to Fatality: An Investigation Based on Concurrent Health Status Evaluation among the Elderly Population in Kerala by Sindhu Joseph et al, made available as preprint on 2021-01-12 at https://medrxiv.org/cgi/content/short/2021.01.06.20249030 [... want %more?]07:23
BrainstormUpdates for Sicily, Italy: +1913 cases (now 111555), +40 deaths (now 2805) since 23 hours ago — Wyoming, United States: +677 cases (now 48072), +33 deaths (now 522) since 23 hours ago — Unknown, Belgium: +126 cases (now 11273) since 23 hours ago — France: +14787 cases (now 2.8 million) since 23 hours ago07:23
BrainstormUpdates for Belgium: +2099 cases (now 667322), +72 deaths (now 20194) since a day ago07:54
BrainstormNew from The Indian Express (Health): Lifestyle: The next 20 days of ICU care will decide baby Musab’s fate against a deadly disease → https://is.gd/MyrZKO08:06
BrainstormNew from r/WorldNews: worldnews: Sweden Finally Tightens Covid Measures After Being Slammed by Virus → https://is.gd/sOMvFq08:54
BrainstormNew from r/Coronavirus: Daily Discussion Thread | January 13, 2021: The WHO pages contain up-to-date and global information. Please refer to our Wiki for additional information. → https://is.gd/v9wL6r09:06
BrainstormNew from The Indian Express: World: Africa secures close to 300 million Covid vaccine doses: report → https://is.gd/lEgyc109:18
BrainstormNew from Medical Xpress: As pandemic worsens, most US states resist restrictions: As the U.S. goes through the most lethal phase of the coronavirus outbreak yet, governors and local officials in hard-hit parts of the country are showing little willingness to impose any new restrictions on businesses to stop the spread. → https://is.gd/2pvAul10:19
BrainstormNew from Medical Xpress: US will require all arriving passengers to get COVID-19 test: Anyone flying to the U.S. will soon need to show proof of a negative test for COVID-19, health officials announced Tuesday. → https://is.gd/PS9gGx10:31
BrainstormNew from Medical Xpress: US COVID-19 deaths hit daily record as China rushes to contain outbreaks: The United States has endured its worst day of the pandemic, with three Americans dying every minute, as China took decisive steps on Wednesday to stamp out a tiny coronavirus outbreak. → https://is.gd/ljMGlt10:43
BrainstormUpdates for Indonesia: +11278 cases (now 858043), +306 deaths (now 24951) since a day ago10:48
BrainstormNew from NPR: India Prepares For Massive Vaccine Drive, But Some Fear It's Moving Too Quickly: Scientists, public health experts and opposition politicians have raised questions about one of the two vaccines the country of 1.4 billion people has authorized for emergency use against COVID-19. → https://is.gd/qMBNoK10:55
BrainstormNew from Medical Xpress: How Ireland became 'most infectious' coronavirus country: In the midst of a third wave of coronavirus infections, Ireland now holds the unhappy title of the nation with the highest transmission rate in the world. → https://is.gd/MuxkQW11:07
DocScrutinizer05>><LjL> de-facto, DocScrutinizer05: uhm... a good point? https://old.reddit.com/r/worldnews/comments/kw62kl/scientists_fear_the_escape_mutant_in_coronavirus/gj2hs8m/?context=3<<  yeah :-(11:26
BrainstormUpdates for Falkland Is.: +3 cases (now 32) since 12 days ago11:38
BrainstormNew from BBC Health: Sinovac: Brazil results show Chinese vaccine 50.4% effective: Latest results show Sinovac's Covid-19 vaccine is less effective in Brazil than previously suggested. → https://is.gd/VgEAvk11:44
BrainstormNew from BMJ: David Oliver: Could we do better on hospital acquired covid-19 in a future wave?: Hospitals are currently in the eye of a covid-19 storm, driven by a rapid rise in community infection rates and more new emergency cases presenting daily. But before the current surge there were... → https://is.gd/eo3nOQ12:08
BrainstormNew from New Scientist: Is the UK right to delay the second dose of the covid-19 vaccines?: To vaccinate more people quickly, the UK is making people wait up to three months for a booster shot rather than the few weeks tested in trials. Here's what the evidence says about the situation → https://is.gd/cWxcRU12:56
DocScrutinizer05de-facto: numbers are about to "stabilize" regarding "CI" it seems13:04
BrainstormNew from The Indian Express: World: China vaccine’s low efficacy due to high-risk group, says Sinovac CEO → https://is.gd/6UnyXW13:09
BrainstormUpdates for Zambia: +2406 cases (now 31100), +31 deaths (now 509) since 23 hours ago13:30
BrainstormNew from r/WorldNews: worldnews: Pakistani police officer escorting polio vaccine team shot dead → https://is.gd/Xdf6PG13:33
BrainstormNew from Medical Xpress: Disneyland to be mass COVID-19 vaccination site: Disneyland will become the first mass COVID-19 vaccination site in Orange County, California, officials announced Monday. → https://is.gd/xVdxkW13:45
BrainstormNew from BMJ: Covid-19: Many ICU staff in England report symptoms of PTSD, severe depression, or anxiety, study reports: Nearly half of intensive care unit (ICU) and anaesthetic staff surveyed for a study reported symptoms consistent with a probable diagnosis of post-traumatic stress disorder (PTSD), severe depression,... → https://is.gd/weNQZ913:57
ubLIX[m]#bang14:31
ubLIX[m]sry. keybinding fail14:31
BrainstormUpdates for Germany: +17778 cases (now 2.0 million) since 22 hours ago — Switzerland: +50 cases (now 487407) since 22 hours ago14:32
BrainstormNew from Medical Xpress: The dirty life and times of SARS-CoV-2: It took the coronavirus for scientists to finally question the standard ethics of the placebo controlled study. Even the top mainstream science journals, like Nature, have now at long last finally admitted that no one should be putting their elderly parents, children or essential [... want %more?] → https://is.gd/y8QAvz14:33
BrainstormNew from r/WorldNews: worldnews: Covid: Large trial of new treatment begins in UK → https://is.gd/RZYmIe14:58
BrainstormNew from r/WorldNews: worldnews: China's Covid-19 vaccine is 50% effective, lower than the 78% originally touted, Brazil results show → https://is.gd/6OW4Qm15:10
DocScrutinizer05LjL: ^^^ 15:16
DocScrutinizer05whatever the root cause, the result is depressing15:17
BrainstormNew from StatNews: STAT+: Pharmalittle: J&J Covid-19 vaccine production is behind schedule; Slaoui resigns from Operation Warp Speed: J&J expects to release results from its Covid-19 vaccine trial in as little as two weeks, but unanticipated manufacturing delays will prevent the vaccine from getting out the door and… → https://is.gd/OYTJ1C15:35
CoronaBot04/r/covid19: Synairgen announces commencement of dosing in its international Phase III study of inhaled interferon beta in hospitalised COVID-19 patients (83 votes) | https://www.synairgen.com/wp-content/uploads/2021/01/210113-Synairgen-SG018-First-dosing-final-1.pdf | https://redd.it/kwctwu15:49
BrainstormNew from r/WorldNews: worldnews: Hackers leak stolen Pfizer COVID-19 vaccine data online → https://is.gd/GWxzCz15:58
BrainstormNew from r/WorldNews: worldnews: Ohio researchers say they've identified two new Covid strains likely originating in the U.S. → https://is.gd/wz7TVN16:35
BrainstormUpdates for Portugal: +10556 cases (now 507108), +156 deaths (now 8236) since 22 hours ago16:35
de-factoRKI COVID-19 Germany 2021-01-13: Weekly Incidence 155.0/100k, Infections +19600 (1953426 total), Fatalities +1060 (42637 total), COVID@ICU 5162 (incl 2972 on ventilator)16:46
BrainstormNew from Virological.org: Tracking the international spread of SARS-CoV-2 lineages B.1.1.7 and B.1.351/501Y-V2:  Áine O’Toole, MSc 1,$, *, Verity Hill, MSc 1 *, Oliver G. Pybus, DPhil 2 , Alexander Watts, PhD 3,4 , Isaac I. Bogoch, MD 5,6 , Kamran Khan MD, MPH 3,4,5 , Jane P. Messina, PhD 7 , The COVID-19 Genomics UK (COG-UK) consortium 8 , Network [... want %more?] → https://is.gd/FVb9TA16:47
de-facto.title https://imgur.com/a/vP0Xfm9 https://i.imgur.com/lx84CjT.png source: https://www.intensivregister.de/#/aktuelle-lage/zeitreihen16:56
Brainstormde-facto: From imgur.com: COVID-19 Germany: Occupied ICU beds and their daily change - Album on Imgur16:56
BrainstormNew from r/WorldNews: worldnews: Chinese COVID-19 vaccine far less effective than initially claimed in Brazil, sparking concerns → https://is.gd/158Oks17:00
BrainstormNew from ClinicalTrials.gov: (news): Antiseptic Mouth Rinses to Reduce Salivary Viral Load in COVID-19 Patients → https://is.gd/qbC0ZM17:13
BrainstormNew from ClinicalTrials.gov: (news): Phase 2 Trial to Evaluate Safety and Efficacy of CYTO-205 in Mild COVID-19 → https://is.gd/xTrkRr17:25
BrainstormUpdates for Sudan: +1378 cases (now 24694), +52 deaths (now 1520) since 22 days ago17:25
BrainstormUpdates for United Kingdom: +31063 cases (now 3.2 million), +937 deaths (now 83772) since 22 hours ago17:44
BrainstormNew from ClinicalTrials.gov: (news): Antiseptic Mouth Rinses to Reduce Salivary Viral Load in COVID-19 Patients → https://is.gd/qbC0ZM17:50
BrainstormNew from Medical Xpress: Spanish judge orders elderly woman to get virus jab: A Spanish judge has ordered a resident of a retirement home to be vaccinated against the new coronavirus despite her daughter's objections, according to a court ruling made public Wednesday. → https://is.gd/SAlsbG18:02
BrainstormUpdates for Netherlands: +5714 cases (now 891328), +132 deaths (now 12678) since 20 hours ago18:09
BrainstormNew from Medical Xpress: Five hurdles in the global COVID-19 vaccine rollout: The unprecedented push to inoculate the world's population against COVID-19 has got off to a sluggish start, triggering a storm of criticism. → https://is.gd/SV5dnj18:15
LjLMatteo Renzi here is making the press conference that may make our government collapse right now18:18
xrogaanhu ho18:30
xrogaanLjL: let us know what happens.18:31
BrainstormNew from Medical Xpress: Scientists developing COVID-19 vaccine nasal spray: Lancaster University researchers have successfully engineered a COVID-19 vaccine which can be administered through the nose. → https://is.gd/W0Typq18:40
BrainstormUpdates for Cuba: +550 cases (now 16044), +3 deaths (now 158) since a day ago — Canada: +4732 cases (now 678791), +127 deaths (now 17299) since 23 hours ago — Isle of Man: +8 cases (now 414) since a day ago — Malawi: +373 cases (now 9400), +19 deaths (now 254) since a day ago18:46
LjLxrogaan: so far... The press conference is over, but I'm not really sure. He basically ruled out creating a new majority with the right wing (but I wouldn't necessarily believe him on that) but didn't rule our anything else, and he didn't really answer any of the questions on whether it's even thinkable to still have Conte as the PM19:10
LjLI assume the answer is "no" and if he accepts to stay in the same majority he'll want his head at least, but I dunno19:10
BrainstormNew from Medical Xpress: Is it OK to exercise when you're sick?: If you are sick and plan to exercise this cold and flu season, experts say to use your head—and recognize the body's warnings signs. → https://is.gd/fHcj2819:16
de-facto.title https://imgur.com/a/hm3YoWI https://i.imgur.com/JsJBwO0.png source: https://www.intensivregister.de/#/aktuelle-lage/zeitreihen19:35
Brainstormde-facto: From imgur.com: COVID-19 Germany: Occupied ICU beds and their relative daily change - Album on Imgur19:35
de-factoDocScrutinizer05, made a graph with relative daily change of occupied ICU beds 19:35
de-factoi.e. change of COVID-19 occupied ICU beds in Germany (difference to previous day) per total occupied COVID-19 ICU beds today19:37
de-factoDaily decline by ~1% now, for the first wave it went up to daily ~5% decline in occupied ICU beds19:39
BrainstormNew from ScienceMag: [Research Articles] Heightened resistance to host type 1 interferons characterizes HIV-1 at transmission and after antiretroviral therapy interruption: Type 1 interferons (IFN-I) are potent innate antiviral effectors that constrain HIV-1 transmission. However, harnessing these cytokines for HIV-1 cure strategies has been hampered [... want %more?] → https://is.gd/Se5L2020:17
BrainstormNew from Gazzetta Ufficiale italiana: MINISTERO DELLO SVILUPPO ECONOMICO - DECRETO 11 dicembre 2020: Liquidazione  coatta  amministrativa  della  «O.P.  Moderna  societa'agricola cooperativa a mutualita'  prevalente»,  in  Campogalliano  enomina del commissario liquidatore. (21A00030) → https://is.gd/7TSWQW20:30
BrainstormUpdates for Spain: +38869 cases (now 2.2 million), +195 deaths (now 52878) since a day ago — Italy: +15773 cases (now 2.3 million), +507 deaths (now 80326) since a day ago — France: +18113 cases (now 2.8 million), +571 deaths (now 68924) since 23 hours ago — Germany: +17565 cases (now 2.0 million), +977 deaths (now 43414) since 23 hours ago20:50
LjLlooks like Spain is the next one to keep an eye on, western Europe-wise http://offloop.net/covid19/?default=United%20Kingdom;France;Italy;Spain&byPopulation=yes&cumulative=no&smooth=yes20:55
de-factowow why are case numbers raising again that steep in Spain?21:09
de-factoanother mutant or import?21:10
CoronaBot04/r/covid19: Review of the Emerging Evidence Demonstrating the Efficacy of Ivermectin in the Prophylaxis and Treatment of COVID-19 (82 votes) | https://www.frontiersin.org/articles/10.3389/fphar.2021.643369/abstract | https://redd.it/kwhm9421:15
BrainstormNew from Medical Xpress: WHO says around 28 mn vaccine doses injected so far: The World Health Organization said Wednesday that about 28 million vaccine doses have been administered so far in the fight against the COVID-19 pandemic—largely in the wealthiest countries. → https://is.gd/OFX4ol21:19
LjLSo Sinovac has 50.4% efficacy in Brazil, 91% in Turkey, and 65% in Indonesia21:22
LjLMight as well be a random number generator21:22
LjLde-facto: I don't know21:22
BrainstormNew from Medical Xpress: Turkey approves China's Sinovac jab: Turkey on Thursday approved the emergency use of a coronavirus jab developed by China's Sinovac, paving the way for a national vaccination drive that will start with healthcare workers. → https://is.gd/vZ3KHQ21:31
BrainstormNew from Medical Xpress: COVID-19 vaccine creates incentive to improve our health: While we wait for our turn to get vaccinated against SARS-CoV-2, we could—and probably should—use the time to make sure we bring our healthiest emotional and physical selves to the treatment, a new review of previous research suggests. → https://is.gd/8mlfm321:44
whytekSpain's got nothing on Ireland.22:07
whytekhttp://offloop.net/covid19/?default=France;Italy;Spain;Ireland&byPopulation=yes&cumulative=no&smooth=yes22:07
whytekBut you notice a very short lived spike. (maybe)22:08
whytekI have no clue what the reporting quality is like for Ireland22:08
BrainstormNew from r/WorldNews: worldnews: Brazil's Bolsonaro sabotaged anti-COVID-19 efforts, says Human Rights Watch → https://is.gd/1XuaNj22:08
whytekBut here's some Irish journo with a wierd mix of catholic self-whipping, or is it sympathy seeking, or is it some weird gloating? https://www.irishtimes.com/news/health/covid-19-how-did-ireland-fall-from-grace-to-its-current-worst-in-world-statistics-1.445660122:10
BrainstormUpdates for Netherlands: +5719 cases (now 891353) since 20 hours ago22:11
whytekSeems to be blaming a combination of people behaving badly (well the irish are notoriously bad at being sick, but it's also a total nanny state)22:13
whytekand.. the new variant22:13
whytekNothing about schools.22:13
whytekAt least it seems they are leaving the schools closed for the moment.22:17
whytekI had never heard of an asparamancer :) https://www.msn.com/en-ie/news/uknews/asparamancer-predicts-when-schools-will-re-open-and-more-about-what-s-to-come-in-2021/ar-BB1cIgCQ22:18
whytek"The world’s only asparamancer — someone who predicts the future through the power of asparagus — has said Irish schools won’t be back until after Easter."22:19
whytekthe power of asparagus...22:19
whytekwell22:19
whytekwho am I to deny that.22:19
BrainstormNew from r/WorldNews: worldnews: Brazil Confirms The Circulation Of A New 'Amazon Rain Forest' Variant Of The Coronavirus → https://is.gd/3FmH1n22:21
BrainstormNew from Medical Xpress: US, UK Covid-19 deaths hit daily records as vaccinations get underway: The United States and Britain endured their worst day of the pandemic as countries around the world tightened virus restrictions on Wednesday and mass vaccination campaigns got under way. → https://is.gd/iVXnoi22:46
BrainstormNew from WebMD: 'Microbiomes' Might Influence COVID-19 Severity: Imbalances in the microbiome may cause continued inflammatory symptoms, often called "long-haul" COVID, the researchers added. → https://is.gd/gFfHMm22:58
BrainstormNew from StatNews: Data fuel debate over whether J&J’s one-dose Covid vaccine will measure up: Johnson & Johnson published updated early data on its Covid-19 vaccine, showing that it provided participants in a clinical trial with at least some immunity after one dose. The question… → https://is.gd/OahkQ723:10
thunorcovid has been blown way out of proportion23:15
AimHerePick the worst terrorist attack in <your country here>'s history. More people than that died today due to Covid1923:17
thunorwho cares23:22
thunormore people die of loads of stuff23:23
thunorsomeone bumped their head today and died23:23
thunorlets all file pavements down23:23
AimHereIf you're just going to say 'who cares' at huge death tolls, that's up to you23:23
LjLif you don't care, get out, it's not your channel23:23
thunorwell i'm here to support covid23:23
thunorlike those people who come round to collect money "for cancer" someone said once23:24
thunorhumans are shit and deserve some pain and misery sometimes23:24
LjLthis definitely isn't a place to "support covid" in the way you mean23:25
LjLyou are quieted, feel free to listen to what is said if you want but you won't be able to speak23:25
BrainstormNew from WebMD: COVID Vaccinations Slowest in Hardest Hit States: The U.S. government’s race to beat back the pandemic with vaccines — dubbed Operation Warp Speed -- has faltered in its last phase: Getting badly needed doses to the public. → https://is.gd/I8C0dt23:35
de-factomost countries have excess mortality due to something that happened 2020, and very hard work has been invested to prevent a worse outcome, hence that excess mortality only is the hint of what would have happened if worse outcome would not have been prevented by all what was done to prevent it23:39

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