| LjL | uh before i was mainly attributing this to forged tests, but maybe India just needs to get better tests | 00:07 |
|---|---|---|
| Brainstorm | New from NPR: Pfizer Seeks Full FDA Approval For COVID-19 Vaccine: The agency's approval of the Pfizer-BioNTech vaccine — shown to be 95% effective — would go beyond the speedier and less rigorous emergency use authorization currently granted to the vaccine. → https://is.gd/rcpnCE | 00:07 |
| * de-facto keeps his mouth shut | 00:10 | |
| Brainstorm | New from The Indian Express: World: UK authorities label version of Indian Covid variant as concerning → https://is.gd/ouQPVy | 00:49 |
| Brainstorm | New from COVID19 Vaccine Tracker: Shannon McKearnan: AnGes: AG0301-COVID19 → https://is.gd/HrYyfo | 01:21 |
| Brainstorm | Updates for Guatemala: +1257 cases (now 233696), +18 deaths (now 7695) since 22 hours ago — Germany: +9017 cases (now 3.5 million) since 21 hours ago | 01:33 |
| Brainstorm | Updates for Curacao: +6 cases (now 12228) since 23 hours ago | 02:11 |
| Brainstorm | Updates for Colombia: +17525 cases (now 3.0 million), +453 deaths (now 76867) since a day ago — Ukraine: +5773 cases (now 2.1 million), +286 deaths (now 46582) since 22 hours ago — Netherlands: +5447 cases (now 1.6 million), +16 deaths (now 17407) since 22 hours ago — Bahrain: +1706 cases (now 186403), +4 deaths (now 674) since a day ago | 02:36 |
| Brainstorm | New from r/WorldNews: worldnews: COVID is killing 120 people an hour in India, and it could stay "really grim" for months → https://is.gd/YCgdJ7 | 02:52 |
| Brainstorm | Updates for Paraguay: +2693 cases (now 294233), +91 deaths (now 6974) since 23 hours ago — Egypt: +1125 cases (now 235140), +65 deaths (now 13779) since a day ago — Panama: +398 cases (now 366762), +3 deaths (now 6258) since a day ago — Anguilla: +4 cases (now 99) since 5 days ago | 03:38 |
| Brainstorm | New from r/WorldNews: worldnews: India's Covid crisis delivers a blow to brand Modi → https://is.gd/IM5uyd | 04:26 |
| LjL | <CoronaBot> /r/coronavirus: The virus is an airborne threat, the C.D.C. acknowledges. (1058 votes) | 04:30 |
| LjL | <CoronaBot> https://www.nytimes.com/2021/05/07/health/coronavirus-airborne-threat.html | https://redd.it/n77lk1 | 04:30 |
| LjL | wow, seriously? | 04:30 |
| LjL | shocking | 04:30 |
| Brainstorm | New from The Indian Express: World: Britain free of coronavirus by August, says outgoing vaccine task force chief: Report → https://is.gd/lRNtlm | 04:36 |
| Brainstorm | Updates for France: +19772 cases (now 5.8 million), +243 deaths (now 106119) since 20 hours ago — Germany: +11544 cases (now 3.5 million) since 22 hours ago — Netherlands: +5616 cases (now 1.6 million), +16 deaths (now 17413) since 20 hours ago — United Kingdom: +1869 cases (now 4.4 million), +11 deaths (now 127724) since 20 hours ago | 04:40 |
| iphony | LjL: seems like they are saying 6 feet distance may not be enough | 05:03 |
| LjL | of course it's not enough | 05:05 |
| LjL | this was known by anyone with even a semblance of a clue for months | 05:05 |
| ryouma | quite early on this was reported | 05:06 |
| ryouma | but it became a sort of anchor/meme | 05:07 |
| ryouma | the desire for certainty outweighing dtrt is really common among humans | 05:08 |
| Brainstorm | Updates for South Korea: +701 cases (now 126745), +5 deaths (now 1865) since a day ago | 05:30 |
| Brainstorm | New from The Indian Express (Health): Health: Long COVID: The impact of coronavirus on humans → https://is.gd/bdb1nn | 05:48 |
| iphony | so how far is enough? | 05:51 |
| iphony | well afaik 6' has been the CDC guideline , so | 05:51 |
| Brainstorm | Updates for Belgium: +3723 cases (now 1.0 million), +39 deaths (now 24483) since 23 hours ago | 06:07 |
| ryouma | cdc does not always have credibility | 06:15 |
| ryouma | it was a rule from the 1800s. some new research and speculation has been done. | 06:17 |
| iphony | sure | 06:17 |
| ryouma | one question is whether even 40ft is enough at least indoors. idk if that has been resolved. | 06:18 |
| iphony | but I believe this reference was being used for how many children could be in a classroom, there was even a push to make it 3 feet instead, not sure what ended up being allowed where | 06:18 |
| ryouma | yeah dunno | 06:18 |
| ryouma | oh maybe i am making an even bigger fool of myself having logged in after some relevant paper factoid was posted | 06:19 |
| iphony | am sure its distance+time, but few weeks back they were saying 2/3 is enough outdoors now, mask, 6' and outdoors | 06:19 |
| ryouma | what are singles doing about dating rituals and practices these days? | 06:20 |
| iphony | imo they should have made a push to give people rubber wristbands showing vaccination to promote it, somehow they are pretending it's protected health information like HIV status | 06:21 |
| ryouma | they give uot stickers that say you voted | 06:23 |
| Brainstorm | New from r/WorldNews: worldnews: China ‘probed WEAPONISING coronaviruses five years before Covid outbreak & predicted WW3 fought with bio-weapons’ → https://is.gd/faLhGj | 06:29 |
| ryouma | what is the theory of bioweapons? that they are not transmissible? that you attack the whole rest of the world but vaccinate your country? that borders are closed? | 06:39 |
| ryouma | i don't get it | 06:40 |
| the-wes | combine it with the "escaped from a lab" narrative | 07:12 |
| the-wes | they were in the process of engineering it so that it would only affect white people, but it got out early and now everyone has a vaccine | 07:13 |
| the-wes | so they have to start over | 07:13 |
| Brainstorm | Updates for Tamil Nadu, India: +26465 cases (now 1.3 million), +197 deaths (now 15171) since 20 hours ago — West Bengal, India: +19216 cases (now 954282), +112 deaths (now 12076) since 20 hours ago — Odisha, India: +12238 cases (now 512400), +19 deaths (now 2140) since 20 hours ago — Uttarakhand, India: +9642 cases (now 229993), +137 deaths (now 3430) since 20 hours ago | 07:34 |
| CoronaBot | /r/covid19: Fatal COVID-19 outcomes are associated with an antibody response targeting epitopes shared with endemic coronaviruses (84 votes) | https://www.medrxiv.org/content/10.1101/2021.05.04.21256571v1 | https://redd.it/n7ehjz | 07:37 |
| finely[m] | <LjL "this was known by anyone with ev"> Seems like the consensus now is most spread is from larger droplets, but there is a lesser risk of finer aerosols that can hang in the air much longer. | 08:17 |
| finely[m] | <the-wes "they were in the process of engi"> How exactly would 'they' do that when 'white' people is a social construct with no basis in biology? | 08:21 |
| Brainstorm | New from r/Coronavirus: Daily Discussion Thread | May 08, 2021: Please refer to our Wiki for more information on COVID-19 and our sub. You can find answers to frequently asked questions in our FAQ , where there is valuable information such as our: → https://is.gd/kzCvKg | 09:05 |
| Brainstorm | Updates for Kyrgyzstan: +416 cases (now 98079), +6 deaths (now 1649) since a day ago — Germany: +160 deaths (now 84668) since 22 hours ago | 09:38 |
| spybert | finely[m]: the "white people as a social construct" thing doesn't fly in biology. A bit of data mining on the human genome will quickly give you a cluster of genes identifying the group in question. It is indeed possible to create a bioweapon to attack such a group. However, the covid-19 virus does not appear to be anything like that. | 09:48 |
| * kreyren uploaded an image: (193KiB) < https://matrix.org/_matrix/media/r0/download/matrix.org/oHTeoWGowKwmQSbSrImadFCK/Tusky_Share_Media_20210508_095827.png > | 09:58 | |
| kreyren | thoughs? | 09:58 |
| Brainstorm | Updates for Lithuania: +1522 cases (now 256906), +5 deaths (now 4024) since 23 hours ago | 10:03 |
| spybert | kreyren: Anti-vaxxer nonsense | 10:04 |
| kreyren | <spybert "KREYREN: Anti-vaxxer nonsense"> seems like it, but the clams seems to be factual e.g. why J&J had their supply shut down recently | 10:09 |
| kreyren | wasnt able to verify moderna though | 10:10 |
| kreyren | as their vaccine passed 3rd clinical trials? | 10:11 |
| Brainstorm | New from r/WorldNews: worldnews: India's COVID surge claims 'a genuine giant in the field of infectious diseases' → https://is.gd/xceSnY | 10:17 |
| oxek | spybert: haven't you heard that critical race theory goes above biology? | 10:24 |
| Brainstorm | New from r/WorldNews: worldnews: Israel sends additional COVID-19 aid to India to combat severe outbreak → https://is.gd/suECeS | 10:27 |
| Brainstorm | Updates for Saint Lucia: +47 cases (now 4654) since a day ago — Puerto Rico: +12 deaths (now 2367) since 17 hours ago — Cayman Is.: +3 cases (now 548) since 3 days ago | 10:40 |
| finely[m] | <spybert "finely: the "white people as a s"> "Humans are not divided biologically into distinct continental types or racial genetic clusters. Instead, the Western concept of race must be understood as a classification system that emerged from, and in support of, European colonialism, oppression, and discrimination. It thus does not have its roots in biological reality, but in policies of discrimination." | 10:45 |
| highersource[m] | https://rense.com/general96/vaxxed-persons.php | 10:46 |
| spybert | finely[m]: That's funny. A not very useful postmodern take on things. You can't protect minority groups from racial discrimination if you refuse to acknowledge that race exists :-( | 10:49 |
| finely[m] | <spybert "KREYREN: Anti-vaxxer nonsense"> Its possible everything in that poster is factual (though the last bit is a lie of ommision). Conspiracy theories spread quickly when they have a kernel of truth. There are very well reasoned and researched criticisms of how pharmaceutical companies operate - see Ben Goldacres book. | 10:55 |
| finely[m] | <spybert "finely: That's funny. A not ver"> Not post modern. Just plain science. Every geneticist on Earth who is not a racist arsehole agrees there is no such thing as race. Define whiteness genetic terms. | 10:59 |
| finely[m] | The doco series "Exterminate all the brutes" is a fantastic exploration of genicide and colonialism btw. | 11:01 |
| finely[m] | * Not post modern. Just plain science. Every geneticist on Earth who is not a racist arsehole agrees there is no such thing as race. Define whiteness in genetic terms. | 11:01 |
| spybert | You can't reason away racism by claiming there is no such thing as race. You merely turn a blind eye to racism by doing so. | 11:05 |
| finely[m] | I guess it is time again to remind everyone that Russia uses troll farms to spread disinformation about vaccines, amongst other topics. Some new reports China is starting to get into that game as well | 11:09 |
| humpelstilzchen[ | I wonder if anyone ever gets a proof about these russian troll farms that were able to change outcome of elections | 11:12 |
| finely[m] | The doco "agents of chaos" answers those questions. | 11:17 |
| finely[m] | It seem they used to operate to exacerbate divisions in democracies, but have recently started to directly attack elections with the help of hacking units of the GRU. | 11:18 |
| humpelstilzchen[ | HBO? srsly? | 11:23 |
| finely[m] | Or read the government reports the doco is based on. | 11:23 |
| finely[m] | Or the person who went undercover in one | 11:25 |
| finely[m] | https://www.npr.org/sections/parallels/2018/03/15/594062887/some-russians-see-u-s-investigation-into-russian-election-meddling-as-a-soap-ope | 11:25 |
| Brainstorm | Updates for Fiji: +7 cases (now 136) since a day ago — Dominica: +1 cases (now 175) since 5 days ago | 11:30 |
| Brainstorm | New from Reddit (test): CoronavirusUK: By the end of March, 85% of Gibraltar's adult population had been fully vaccinated against Covid-19. Gibraltar has not seen an active Covid infection among it's residents for 3 weeks → https://is.gd/boxT8G | 11:49 |
| Brainstorm | New from Medical Xpress: In fight against COVID variants some firms target T cell jabs: Getting COVID vaccines into the arms of the world's population is an international priority—but will today's jabs stay effective against virus variants that are spreading across the globe? → https://is.gd/iU7i8d | 12:10 |
| spybert | finely[m]: When one considers that Trumps election victory cost us over 500,000 dead, some retaliation might be in order for Russian meddling in our internal affairs. There are plenty of means available to do so. | 12:25 |
| Brainstorm | New from r/WorldNews: worldnews: EU seals deal with Pfizer-BioNTech for potential 1.8 billion COVID-19 doses in its biggest vaccine contract so far. → https://is.gd/mva3Hf | 12:30 |
| Brainstorm | Updates for Malaysia: +4519 cases (now 436944), +25 deaths (now 1657) since 23 hours ago | 12:32 |
| Brainstorm | New from Medical Xpress: EU seals deal for up to 1.8 bn extra BioNTech/Pfizer doses: The EU has concluded a deal with BioNTech/Pfizer for up to 1.8 billion extra doses of its COVID-19 vaccine, European Commission chief Ursula von der Leyen said on Saturday. → https://is.gd/nl3d3O | 12:41 |
| oxek | spybert: I don't see how trump winning has anything to do with people being incapable of washing their hands, wearing eye protection, wearing mouth+nose protection, not gathering, ... | 12:47 |
| oxek | seems like a failure in the individual rather than blaming it on some politician | 12:47 |
| spybert | oxek: A good leader would have persuaded them to do the right thing, rather than the opposite. | 12:48 |
| oxek | I prefer personal responsibility in all things rather than shifting the blame | 12:48 |
| spybert | oxek: You're republican? | 12:49 |
| oxek | definitely not | 12:49 |
| spybert | The problem with things like pandemics is that it requires group cooperation to combat it. Wearing a mask protects others, not you. | 12:50 |
| spybert | Unless of course it's a real N95 mask. | 12:51 |
| spybert | That's why China and Japan had so much more success in controlling the virus. | 12:53 |
| Brainstorm | New from Gazzetta Ufficiale italiana: MINISTERO DELLA SALUTE - ORDINANZA 7 maggio 2021: Ulteriori misure urgenti in materia di contenimento e gestionedell'emergenza epidemiologica da COVID-19 nelle Regioni Basilicata,Calabria e Puglia. (21A02832) → https://is.gd/KYzXML | 13:01 |
| oxek | I don't really see group cooperation in an environment where everyone is living only for themselves | 13:05 |
| Brainstorm | Updates for Myanmar: +30 cases (now 142934) since 8 hours ago | 13:10 |
| Brainstorm | New from Politico: Aid and development: EU pushes back on Biden plan to waive coronavirus vaccine patents → https://is.gd/0olYGQ | 13:22 |
| Brainstorm | New from The Indian Express: World: First case of Indian variant of Covid-19 detected in Sri Lanka → https://is.gd/6MvOuJ | 13:32 |
| de-facto[m] | .title https://mobile.twitter.com/vonderleyen/status/1390967173460463619 | 13:52 |
| Brainstorm | de-facto[m]: From mobile.twitter.com: error parsing title ('NoneType' object has no attribute 'string') | 13:52 |
| de-facto[m] | "Happy to announce that @EU_Commission has just approved a contract for guaranteed 900 million doses (+900 million options) with @BioNTech_Group @Pfizer for 2021-2023. " | 13:54 |
| de-facto[m] | "Other contracts and other vaccine technologies will follow." | 13:55 |
| Brainstorm | Updates for Bangladesh: +1285 cases (now 772127), +45 deaths (now 11878) since a day ago | 13:59 |
| Brainstorm | New from Reddit (test): nCoV: India's Covid crisis delivers a blow to brand Modi | 08MAY21 → https://is.gd/20ONtG | 14:03 |
| Brainstorm | New from Reddit (test): Capri è covid free: submitted by /u/pausacaffenotizie to r/CoronaVirus_ITALIA → https://is.gd/7PyAbq | 14:14 |
| finely[m] | <spybert "finely: When one considers that "> The countries that have really suffered are the ones with extreme right leaders who undermined the public health efforts. | 14:16 |
| Brainstorm | Updates for Belarus: +1369 cases (now 367674), +10 deaths (now 2622) since 21 hours ago | 14:37 |
| Brainstorm | New from The Indian Express (Health): Destination of the week: Greece to reopen museums next week, ahead of tourism → https://is.gd/SwKdDd | 14:55 |
| Brainstorm | New from The Indian Express: World: UK finalises post-lockdown traffic light travel system; 12 countries on ‘green list’ → https://is.gd/ycD8r4 | 15:16 |
| Brainstorm | New from Politico: Coronavirus: Pope backs coronavirus vaccine patent waivers → https://is.gd/ohcmjg | 15:26 |
| Brainstorm | Updates for Nepal: +8287 cases (now 385890), +53 deaths (now 3632) since a day ago | 15:39 |
| Brainstorm | New from r/WorldNews: worldnews: Key Covid-19 indicators began surging in February, and yet governments in India failed to act → https://is.gd/qTBM1E | 15:47 |
| Brainstorm | New from r/WorldNews: worldnews: China was preparing for a Third World War with biological weapons - including coronavirus - SIX years ago → https://old.reddit.com/r/worldnews/comments/n7pgkv/china_was_preparing_for_a_third_world_war_with/ | 15:57 |
| CoronaBot | /r/coronavirus: The virus is an airborne threat, the C.D.C. acknowledges. (10001 votes) | https://www.nytimes.com/2021/05/07/health/coronavirus-airborne-threat.html | https://redd.it/n77lk1 | 15:58 |
| Brainstorm | New from NPR: Ramping Up Its COVID Response, EU Will Buy Up To 1.8B Doses Of Pfizer Vaccine: The agreement provides a significant boost to the European Union's goal of getting 70% of adults vaccinated. Currently, around a quarter of the bloc's population is vaccinated. → https://is.gd/am8375 | 16:18 |
| Brainstorm | Updates for Portugal: +406 cases (now 839258), +2 deaths (now 16991) since 22 hours ago — Vietnam: +93 cases (now 3230) since 23 hours ago — Switzerland: +2 deaths (now 10704) since 19 hours ago | 16:41 |
| Brainstorm | Updates for Germany: +168 deaths (now 84711) since 23 hours ago | 17:06 |
| LjL | Brainstorm: New from Reddit (test): Capri è covid free: submitted by /u/pausacaffenotizie to r/CoronaVirus_ITALIA → https://is.gd/7PyAbq | 17:27 |
| LjL | So they did it anyway. Government said not to, but they did it anyway | 17:27 |
| LjL | Touristic islands = tourist money = vaccinate first | 17:28 |
| LjL | Disgusting | 17:28 |
| Brainstorm | New from r/WorldNews: worldnews: Pope Francis backs vaccine patents waiver to enable 'universal access to vaccines' → https://is.gd/L849J9 | 17:32 |
| Brainstorm | New from Reddit (test): Saturday 08 May 2021 Update: submitted by /u/HippolasCage to r/CoronavirusUK → https://is.gd/Yalnxr | 17:42 |
| Brainstorm | Updates for Canada: +7035 cases (now 1.3 million), +40 deaths (now 24538) since 21 hours ago | 18:08 |
| Brainstorm | New from r/WorldNews: worldnews: Drink Cow Urine To Stop Coronavirus Spread, BJP MLA Urges All; Demonstrates On Camera → https://is.gd/ZXnJBj | 19:05 |
| Brainstorm | New from r/WorldNews: worldnews: Covid-sparked fungal infection assuming epidemic proportions | India News → https://is.gd/4pJgDN | 19:25 |
| Brainstorm | Updates for Italy: +10174 cases (now 4.1 million), +224 deaths (now 122694) since a day ago — Timor-Leste: +146 cases (now 3111) since a day ago | 19:35 |
| CoronaBot | /r/covid19: Discovery of naturally occurring inhibitors against SARS-CoV-2 3CLpro from Ginkgo biloba leaves via large-scale screening (80 votes) | https://www.sciencedirect.com/science/article/pii/S0367326X21000848 | https://redd.it/n7mc2k | 19:42 |
| de-facto | yuta, ^^ | 19:48 |
| yuta | yes de-facto :) | 19:49 |
| de-facto | isnt Ginkgo quite popular in Japan? :D | 19:49 |
| de-facto | because of what CoronaBot just posted there | 19:50 |
| de-facto | .title https://www.sciencedirect.com/science/article/pii/S0367326X21000848 | 19:50 |
| Brainstorm | de-facto: From www.sciencedirect.com: Discovery of naturally occurring inhibitors against SARS-CoV-2 3CLpro from Ginkgo biloba leaves via large-scale screening - ScienceDirect | 19:50 |
| Brainstorm | New from r/WorldNews: worldnews: Covid: Macron calls on US to drop vaccine export bans → https://is.gd/Et6w8X | 19:56 |
| de-facto | question is can those concentrations they mention there be reached in vivo when eating Ginkgo Biloba? | 20:03 |
| yuta | de-facto: hold on | 20:04 |
| yuta | de-facto: his is not yet a topic of discussion in Japan. There is a tea of Ginkgo biloba. | 20:06 |
| yuta | de-facto: This is not yet a topic of discussion in Japan. There is a tea of Ginkgo biloba. | 20:06 |
| Brainstorm | New from r/WorldNews: worldnews: Besides COVID-19, India is also fighting with vulture journalists, who are spreading more panic and despair than pandemic → https://is.gd/Q7VJuO | 20:06 |
| yuta | de-facto: good infomation , thanks. | 20:06 |
| de-facto | i just have seen the title there, i do not know if it works in people, but it certainly is interesting | 20:09 |
| LjL | synthetic peptide vaccines https://www.news-medical.net/amp/news/20201203/Novel-e2809cmultitopee2809d-vaccine-shows-promise-in-the-fight-against-COVID-19.aspx | 20:09 |
| Brainstorm | New from Politico: Borders: Von der Leyen: Green passes to boost tourism ‘on track’ for June → https://is.gd/sL2I5f | 20:16 |
| de-facto | interesting LjL | 20:20 |
| de-facto | .title https://www.biorxiv.org/content/10.1101/2020.11.30.399154v1 that seems to be their paper | 20:21 |
| Brainstorm | de-facto, the URL could not be loaded | 20:21 |
| de-facto | "A Novel SARS-CoV-2 Multitope Protein/Peptide Vaccine Candidate is Highly Immunogenic and Prevents Lung Infection in an Adeno Associated Virus Human Angiotensin-Converting Enzyme 2 (AAV hACE2) Mouse Model" | 20:21 |
| LjL | i just don't know whether the logistics of this kind of thing would be any easier than mRNA | 20:22 |
| LjL | ultimately i think whatever scales best wins (if it works) | 20:22 |
| de-facto | soon we will have normal fridge stable mRNA | 20:23 |
| de-facto | i like the multitope approach, probably makes evasion much harder when SARS-CoV-2 is attacked from multiple directions at the same time | 20:29 |
| Brainstorm | Updates for Bolivia: +1963 cases (now 316153), +31 deaths (now 13182) since a day ago | 20:37 |
| de-facto | .title https://covid19.trackvaccines.org/vaccines/43/ LjL, i think its this one there | 20:38 |
| Brainstorm | de-facto: From covid19.trackvaccines.org: COVAXX: UB-612 – COVID19 Vaccine Tracker | 20:38 |
| CoronaBot | /r/coronavirus: Pfizer/BioNTech seeks full FDA approval for its Covid-19 vaccine (10002 votes) | https://www.cnn.com/2021/05/07/health/pfizer-biontech-fda-approval-bla-vaccine/index.html | https://redd.it/n6vpx6 | 20:48 |
| LjL | de-facto, oh wow and it's already in phase 3? although a small phase 3 | 20:49 |
| Arsanerit | When will we get the Curevac vaccine? | 20:51 |
| LjL | Arsanerit, their phase 3 is still not done so i dunno | 20:53 |
| Arsanerit | Why is it taking so much longer than with other (m)RNA vaccines? | 20:54 |
| LjL | the phase 3 only started in october | 20:56 |
| Arsanerit | And aren't some widely used vaccines also still officially in phase 3, but with pre-authorisation / emergency approval? | 20:56 |
| LjL | i assume it's a fair bit smaller than Pfizer | 20:56 |
| LjL | Arsanerit, yes but usually some phase 3 data are available. technically the phase 3's don't end for like a couple of years | 20:56 |
| Arsanerit | True, it's as if BioNTech would have gone completely alone and not teaming up with Pfizer...? | 20:57 |
| LjL | i don't know about their respective size, but perhaps | 20:58 |
| LjL | anyway they're in rolling evaluation with the EMA since february https://www.curevac.com/en/2021/02/12/curevac-initiates-rolling-submission-with-european-medicines-agency-for-covid-19-vaccine-candidate-cvncov/ | 20:58 |
| Arsanerit | Ok. | 20:59 |
| Brainstorm | Updates for India: +4098 deaths (now 238270) since 23 hours ago — France: +148 deaths (now 106219) since 23 hours ago | 21:02 |
| Brainstorm | New from r/WorldNews: worldnews: 2015 research paper by Chinese scientists reveals nefarious plans to weaponise the SARS Coronavirus. → https://is.gd/renjN1 | 21:18 |
| -RSSBot[LjLmatrix- Recent Commits to links:master: Remove duplicate study on infection in animals ( https://github.com/ljl-covid/links/commit/2ee56e5f59341125b58f7a82a8219dd550d01822 ) | 21:28 | |
| Brainstorm | New from https://covid19.specops.network : Remove duplicate study on infection in animals: Removing the preprint, published study is in the Epidemiology section → https://is.gd/nALOyd | 21:28 |
| CoronaBot | /r/covid19: BNT162b2 mRNA Covid-19 vaccine does not impair sperm parameters (86 votes) | https://www.medrxiv.org/content/10.1101/2021.04.30.21255690v1 | https://redd.it/n7qx6s | 21:48 |
| de-facto | Arsanerit, https://www.reuters.com/business/healthcare-pharmaceuticals/curevac-says-well-track-request-vaccine-approval-planned-2021-05-05/ maybe June or July? | 21:54 |
| de-facto | "For the trial read-out expected later this month, CureVac will publish details on its primary goal of preventing COVID-19 across all virus variants." | 21:55 |
| de-facto | "All infections in the trial will undergo genetic sequencing of any variant, offering a unique picture of the variations of the pathogen in Europe and Latin America." | 21:56 |
| de-facto | so that might be quite interesting, i am looking very much forward to that | 21:56 |
| Arsanerit | Ok! | 21:58 |
| de-facto | so i hope its only a question of weeks, we will see | 22:02 |
| de-facto | the cool thing might be that it will be stable at fridge temp for 3 months or such | 22:08 |
| de-facto | that might make all the logistics much easier | 22:08 |
| de-facto | and CureVac only needs 12µg mRNA per dose, for comparison BioNTech would need 30µg mRNA (2.5-fold more production capacity required) and ModeRNA even 100µg mRNA (8.3-fold more production capacity required) | 22:11 |
| LjL | de-facto: how likely is it that for example Moderna would work anyway even with 1/10 the dose? | 22:22 |
| Brainstorm | Updates for Uganda: +84 cases (now 42308) since a day ago | 22:29 |
| de-facto | LjL, i am not sure, all of them encode the same version of the spike-glycoprotein (so far no variants), but they have different codon optimizations and they have different prefix and postfix code | 22:30 |
| de-facto | the prefix and postfix code determines something like the translation frequency and also how many times it can be translated to proteins until it gets trashed | 22:30 |
| de-facto | so it might very well be that those differences may reflect that "translation" efficiency and result roughly in the same amount of s-protein, but that is my speculation on it | 22:31 |
| de-facto | also it might be that they employed different metrics or goals in their phase 1/2 dose escalation studies | 22:32 |
| de-facto | LjL, i guess one could search that dose escalation and determination study for mRNA-1273 they probably have 1/10th dose in there | 22:33 |
| Brainstorm | New from Medical Xpress: Merkel urges US to export COVID vaccines: German Chancellor Angela Merkel on Saturday urged the United States to export coronavirus vaccines made on its soil, as she rejected a patent waiver call from Washington for the jabs. → https://is.gd/w2Ajmc | 23:12 |
| de-facto | .title https://www.nejm.org/doi/full/10.1056/nejmoa2022483 | 23:57 |
| Brainstorm | de-facto: From www.nejm.org: An mRNA Vaccine against SARS-CoV-2 — Preliminary Report | NEJM | 23:57 |
| de-facto | Neutralization responses: "The lowest responses were in the 25-μg dose group, with a geometric mean ID50 of 112.3 (95% CI, 71.2 to 177.1) at day 43; the higher responses in the 100-μg and 250-μg groups were similar in magnitude (geometric mean ID50, 343.8 [95% CI, 261.2 to 452.7] and 332.2 [95% CI, 266.3 to 414.5], respectively, at day 43)." | 23:59 |
| de-facto | so i guess they went for saturation while limiting reactogenicity | 23:59 |
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